Meeting report for the 1st skin microbiota workshop, boulder, CO October 15-16 2012

Standards in Genomic Sciences - Tập 9 - Trang 1-7 - 2014
Jack A Gilbert1, Madeleine Ball2, Paul Blainey3, Martin J Blaser4, Brendan JM Bohannan5, Ashley Bateman5, John Bunge6, Maria Gloria Dominguez-Bello7,8, Slava Epstein9, Noah Fierer10, Dirk Gevers11, Tracy Grikscheit12, Leila J Hamdan13, James Harvey14, Curtis Huttenhower15, Benjamin Kirkup16,17, Heidi H Kong18, Christian Lauber19, Katherine P Lemon20,21, Susan V Lynch22, Lance Martin23, Charlene Mello24, Joseph Palma24, Roy Parker25,26, Joseph Petrosino27, Julia A Segre28, Leslie Vosshall29, Rui Yi30, Rob Knight25,26
1Argonne National Laboratory, Argonne, IL, and Department of Ecology and Evolution, University of Chicago, Chicago, USA
2Department of Genetics, Harvard Medical School, Boston, USA
3Broad Institute and MIT Department of Biological Engineering, Cambridge, USA
4Department of Medicine, NYU Langone Medical Center, and New York Harbor VA Medical Center, New York, USA
5Institute of Ecology and Evolution, University of Oregon, Eugene, USA
6Department of Statistical Science, Cornell University, Ithaca, USA
7Department of Medicine, New York University, New York, USA
8Department of Biology, University of Puerto Rico, Puerto Rico, USA
9Department of Biology, Northeastern University, Boston, USA
10Department of Ecology and Evolutionary Biology and CIRES, University of Colorado at Boulder, Boulder, USA
11The Broad Institute of MIT and Harvard, Cambridge, USA
12Division of Pediatric Surgery, Keck School of Medicine, USC, Saban Research Institute, Children’s Hospital Los Angeles, Los Angeles, USA
13George Mason University, Manassas, USA
14US Army Research Office, Research Triangle Park, USA
15Department of Biostatistics, Harvard School of Public Health, Boston, USA
16Department of Wound Infections, Walter Reed Army Institute of Research, Silver Spring, USA
17Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, USA
18National Cancer Institute, National Institutes of Health, Dermatology Branch, Center for Cancer Research, Bethesda, USA
19CIRES, University of Colorado at Boulder, Boulder, USA
20Department of Microbiology, The Forsyth Institute, Cambridge, USA
21Division of Infectious Diseases, Boston Children’s Hospital, Boston, USA
22Department of Medicine, Division of Gastroenterology, University of California San Francisco, San Francisco, USA
23Department of Bioengineering, Program in Epithelial Biology, Stanford University School of Medicine and Stanford University, Stanford, USA
24US Natick Soldier Center, Natick, USA
25Howard Hughes Medical Institute, Boulder, USA
26Department of Chemistry & Biochemistry, and BioFrontiers Institute, University of Colorado at Boulder, Boulder, USA
27Department of Molecular Virology and Microbiology, Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, USA
28National Human Genome Research Institute, NIH, Bethesda, USA
29Howard Hughes Medical Institute, The Rockefeller University, New York, USA
30Department of Molecular, Cellular & Developmental Biology, University of Colorado, Boulder, USA

Tóm tắt

This report details the outcome of the 1st Skin Microbiota Workshop, Boulder, CO, held on October 15th-16th 2012. The workshop was arranged to bring Department of Defense personnel together with experts in microbial ecology, human skin physiology and anatomy, and computational techniques for interrogating the microbiome to define research frontiers at the intersection of these important areas. The workshop outlined a series of questions and created several working groups to address those questions, specifically to promote interdisciplinary activity and potential future collaboration. The US Army provided generous grant support and the meeting was organized and hosted by the University of Colorado at Boulder. A primary forward vision of the meeting was the importance of understanding skin microbial communities to improve the health and stealth of US Army warfighters.

Tài liệu tham khảo

Segre JA: Epidermal barrier formation and recovery in skin disorders. J Clin Invest 2006, 116: 1150–1158. 10.1172/JCI28521 Grice EA, Segre JA: The skin microbiome. Nat Rev Microbiol 2011, 9: 244–253. 10.1038/nrmicro2537 Grice EA, Kong HH, Renaud G, Young AC, Bouffard GG, Blakesley RW, Wolfsberg TG, Turner ML, Segre JA, NISC comparative sequencing program: A diversity profile of the human skin microbiota. Genome Res 2008, 18: 1043–1050. 10.1101/gr.075549.107 Grice EA, Kong HH, Conlan S, Deming CB, Davis J, Young AC, Bouffard GG, Blakesley RW, Murray PR, Green ED, Turner ML, Segre JA, NISC Comparative Sequencing Program: Topographical and temporal diversity of the human skin microbiome. Science 2009, 324: 1190–1192. 10.1126/science.1171700 Costello EK, Lauber CL, Hamady M, Fierer N, Gordon JI, Knight R: Bacterial community variation in human body habitats across space and time. Science 2009, 326: 1694–1697. 10.1126/science.1177486 Egert M, Schmidt I, Höhne H-M, Lachnit T, Schmitz RA, Breves R: rRNA-based profiling of bacteria in the axilla of healthy males suggests right-left asymmetry in bacterial activity. FEMS Microbiol Ecol 2011, 77: 146–153. 10.1111/j.1574-6941.2011.01097.x Fierer N, Lauber CL, Zhou N, McDonald D, Costello EK, Knight R: Forensic identification using skin bacterial communities. Proc Natl Acad Sci U S A 2010, 107: 6477–6481. 10.1073/pnas.1000162107 Caporaso JG, Lauber CL, Costello EK, Berg-Lyons D, Gonzalez A, Stombaugh J, Knights D, Gajer P, Ravel J, Fierer N, Gordon JI, Knight R: Moving pictures of the human microbiome. Genome Biol 2011, 12: R50. 10.1186/gb-2011-12-5-r50 Leyden JJ, McGinley KJ, Hölzle E, Labows JN, Kligman AM: The microbiology of the human axilla and its relationship to axillary odor. J Invest Dermatol 1981, 77: 413–416. 10.1111/1523-1747.ep12494624 Natsch A, Derrer S, Flachsmann F, Schmid J: A broad diversity of volatile carboxylic acids, released by a bacterial aminoacylase from axilla secretions, as candidate molecules for the determination of human-body odor type. Chem Biodivers 2006, 3: 1–20. 10.1002/cbdv.200690015 Troccaz M, Borchard G, Vuilleumier C, Raviot-Derrien S, Niclass Y, Beccucci S, Starkenmann C: Gender-specific differences between the concentrations of nonvolatile (R)/(S)-3-methyl-3-sulfanylhexan-1-Ol and (R)/(S)-3-hydroxy-3-methyl-hexanoic acid odor precursors in axillary secretions. Chem Senses 2009, 34: 203–210. Barzantny H, Schröder J, Strotmeier J, Fredrich E, Brune I, Tauch A: The transcriptional regulatory network of Corynebacterium jeikeium K411 and its interaction with metabolic routes contributing to human body odor formation. J Biotechnol 2012, 159: 235–248. 10.1016/j.jbiotec.2012.01.021 Verhulst NO, Beijleveld H, Knols BG, Takken W, Schraa G, Bouwmeester HJ, Smallegange RC: Cultured skin microbiota attracts malaria mosquitoes. Malar J 2009, 8: 302. 10.1186/1475-2875-8-302 Verhulst NO, Takken W, Dicke M, Schraa G, Smallegange RC: Chemical ecology of interactions between human skin microbiota and mosquitoes. FEMS Microbiol Ecol 2010, 74: 1–9. 10.1111/j.1574-6941.2010.00908.x Verhulst NO, Andriessen R, Groenhagen U, Bukovinszkiné Kiss G, Schulz S, Takken W, van Loon JJA, Schraa G, Smallegange RC: Differential attraction of malaria mosquitoes to volatile blends produced by human skin bacteria. PloS One 2010, 5: e15829. 10.1371/journal.pone.0015829 Verhulst NO, Qiu YT, Beijleveld H, Maliepaard C, Knights D, Schulz S, Berg-Lyons D, Lauber CL, Verduijn W, Haasnoot GW, Mumm R, Bouwmeester HJ, Claas FHJ, Dicke M, van Loon JJA, Takken W, Knight R, Smallegange RC: Composition of human skin microbiota affects attractiveness to malaria mosquitoes. PloS One 2011, 6: e28991. 10.1371/journal.pone.0028991 Kong HH: Skin microbiome: genomics-based insights into the diversity and role of skin microbes. Trends Mol Med 2011, 17: 320–328. 10.1016/j.molmed.2011.01.013 Evans CA, Smith WM, Johnston EA, Giblett ER: Bacterial flora of the normal human skin. J Invest Dermatol 1950, 15: 305–324. 10.1038/jid.1950.45 Shehadeh NH, Kligman AM: The effect of topical antibacterial agents on the bacterial flora of the axilla. J Invest Dermatol 1963, 40: 61–71. Leyden JJ, McGinley KJ, Mills OH, Kligman AM: Age-related changes in the resident bacterial flora of the human face. J Invest Dermatol 1975, 65: 379–381. 10.1111/1523-1747.ep12607630 Huttenhower C, Gevers D, Knight R, Abubucker S, Badger JH, Chinwalla AT, Creasy HH, Earl AM, FitzGerald MG, Fulton RS, Giglio MG, Hallsworth-Pepin K, Lobos EA, Madupu R, Magrini V, Martin JC, Mitreva M, Muzny DM, Sodergren EJ, Versalovic J, Wollam AM, Worley KC, Wortman JR, Young SK, Zeng Q, Aagaard KM, Abolude OO, Allen-Vercoe E, Alm EJ, Alvarado L, et al.: Structure, function and diversity of the healthy human microbiome. Nature 2012, 486: 207–214. 10.1038/nature11234 Dominguez-Bello MG, Costello EK, Contreras M, Magris M, Hidalgo G, Fierer N, Knight R: Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci U S A 2010, 107: 11971–11975. 10.1073/pnas.1002601107 Oh J, Conlan S, Polley EC, Segre JA, Kong HH: Shifts in human skin and nares microbiota of healthy children and adults. Genome Med 2012, 4: 77. 10.1186/gm378 Blaser MJ, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Estrada I, Gao Z, Clemente JC, Costello EK, Knight R: Distinct cutaneous bacterial assemblages in a sampling of South American Amerindians and US residents. ISME J 2013, 7: 85–95. 10.1038/ismej.2012.81 Yilmaz P, Kottmann R, Field D, Knight R, Cole JR, Amaral-Zettler L, Gilbert JA, Karsch-Mizrachi I, Johnston A, Cochrane G, Vaughan R, Hunter C, Park J, Morrison N, Rocca-Serra P, Sterk P, Arumugam M, Bailey M, Baumgartner L, Birren BW, Blaser MJ, Bonazzi V, Booth T, Bork P, Bushman FD, Buttigieg PL, Chain PSG, Charlson E, Costello EK, Huot-Creasy H, et al.: Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications. Nat Biotechnol 2011, 29: 415–420. 10.1038/nbt.1823 Gilbert JA, Meyer F, Jansson J, Gordon J, Pace N, Tiedje J, Ley R, Fierer N, Field D, Kyrpides N, Glöckner F-O, Klenk H-P, Wommack KE, Glass E, Docherty K, Gallery R, Stevens R, Knight R: The earth microbiome project: meeting report of the “1 EMP meeting on sample selection and acquisition” at Argonne National Laboratory October 6 2010. Stand Genomic Sci 2010, 3: 249–253. 10.4056/aigs.1443528
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Standards in Genomic Sciences

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