The formalin test: scoring properties of the first and second phases of the pain response in rats

Abbott, 1986, The stress of a novel environment reduces formalin pain: possible role of serotonin, Eur. J. Pharmacol., 126, 141, 10.1016/0014-2999(86)90750-8 Abbott, 1986, A dose-ratio study of mu and kappa agonists in formalin and thermal pain, Life Sci., 39, 2017, 10.1016/0024-3205(86)90325-5 Abbott, 1988, Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin test, Eur. J. Pharmacol., 152, 93, 10.1016/0014-2999(88)90839-4 Abbott, 1988, Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats, Life Sci., 43, 1685, 10.1016/0024-3205(88)90479-1 Abbott, 1988, Effect of 5-hydroxytryptamine precursors on morphine analgesia in the formalin test, Pharmacol. Biochem. Behav., 31, 855, 10.1016/0091-3057(88)90395-4 Ader, 1968, Effects of early experiences on emotional and physiological reactivity in the rat, J. Comp. Physiol. Psychol., 66, 264, 10.1037/h0026344 Ayhan, 1973, Behavioural and pharmacological studies on morphine-induced excitation of rats. Possible relation to brain catecholamines, Psychopharmacologia, 29, 317, 10.1007/BF00429279 Babbini, 1972, Time-dose relationships for locomotor activity effects of morphine after acute or repeated treatment, Br. J. Pharmacol., 46, 213, 10.1111/j.1476-5381.1972.tb06866.x Bennett, 1988, A peripheral mononeuropathy in the rat that produces disorders of pain sensation like those seen in man, Pain, 33, 87, 10.1016/0304-3959(88)90209-6 Coderre, 1993, The formalin test: a validation of the weighted-scores method of behavioural pain rating, Pain, 54, 43, 10.1016/0304-3959(93)90098-A Dickenson, 1987, Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: different responses to an intrathecal opiate administered pre- or post-formalin, Pain, 30, 339, 10.1016/0304-3959(87)90023-6 Dubuisson, 1977, The formalin test: a quantitative study of the analgesic effects of morphine, meperidine and brain-stem stimulation in rats and cats, Pain, 4, 161, 10.1016/0304-3959(77)90130-0 Dundee, 1960, Alterations in response to somatic pain associated with anaesthesia. II. The effect of thiopentone and pentobarbitone, Br. J. Anaesth., 32, 407, 10.1093/bja/32.9.407 Dunn, 1979, Intracerebral adrenocorticotropic hormone mediates novelty-induced grooming in the rat, Science, 203, 281, 10.1126/science.216073 Fanselow, 1984, Shock-induced analgesia on the formalin test: effects of shock severity, naloxone, hypophysectomy and associative variables, Behav. Neurosci., 98, 79, 10.1037/0735-7044.98.1.79 Fanselow, 1982, Conditioned fear-induced opiate analgesia on the formalin test: evidence for two aversive motivational systems, Learn. Motivat., 13, 200, 10.1016/0023-9690(82)90021-2 Forrest, 1977, Dextroamphetamine with morphine for the treatment of postoperative pain, N. Engl. J. Med., 296, 712, 10.1056/NEJM197703312961303 Franklin, 1989, Techniques for assessing the effects of drugs on nociceptive responses, 145 Franklin, 1993, Pentobarbital, diazepam and ethanol abolish the inter-phase diminution of pain in the formalin test: evidence for pain modulation by GABAA receptors, Pharmacol. Biochem. Behav., 46, 661, 10.1016/0091-3057(93)90558-B Gracely, 1983, Placebo and naloxone can alter post-surgical pain by separate mechanisms, Nature, 306, 264, 10.1038/306264a0 Green, 1979, Naloxone and haloperidol reduce grooming occurring as an after-effect of novelty, Behav. Neurol. Biol., 27, 546, 10.1016/S0163-1047(79)92208-8 Guy, 1992, The behavioral response to formalin in preweanling rats, Pain, 51, 81, 10.1016/0304-3959(92)90012-Z Harris, J.A. and Westbrook, R.F., Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment, Psychopharmacology, in press. Hole, 1993, The tail-flick and formalin tests in rodents: changes in skin temperature as confounding factor, Pain, 53, 247, 10.1016/0304-3959(93)90220-J Hunskaar, 1987, The formalin test in mice: dissociation between inflammatory and non-inflammatory pain, Pain, 30, 103, 10.1016/0304-3959(87)90088-1 Iida, 1974, Relationship between the morphine-induced spontaneous locomotor activity and the concentration of morphine in brain or in plasma of rats (Report 2), Jpn. J. Pharmacol., 24, 88, 10.1016/S0021-5198(19)32271-1 Jaffe, 1990, Opioid agonists and antagonists, 485 Levine, 1986, Method of administration determines the effect of naloxone on pain, Brain Res., 365, 377, 10.1016/0006-8993(86)91653-7 Lin, 1989, Cocaine: evidence for supraspinal, dopamine-mediated, non-opiate analgesia, Brain Res., 479, 306, 10.1016/0006-8993(89)91633-8 Matthies, 1992, Formalin pain is expressed in decerebrate rats but not attenuated by morphine, Pain, 51, 199, 10.1016/0304-3959(92)90261-9 Morgan, 1990, 6-hydroxydopamine lesions of the ventral tegmentum abolish d-amphetamine and morphine analgesia in the formalin test but not in the tail flick test, Brain Res., 519, 144, 10.1016/0006-8993(90)90072-J Morgan, 1991, Dopamine receptor subtypes and formalin test analgesia, Pharmacol. Biochem. Behav., 40, 317, 10.1016/0091-3057(91)90560-O Murray, 1988, Methodological refinements to the mouse paw formalin test, an animal model of tonic pain, J. Pharmacol. Methods, 20, 175, 10.1016/0160-5402(88)90078-2 Neoh, 1992, Does site of injection play any important role in the formalin pain test, Chin. J. Pain, 2, 51 Neoh, 1992, Evaluation of lifting or biting as the indicator for nociceptive behavior response in formalin pain test, Chin. J. Pain, 2, 43 North, 1978, Naloxone reversal of morphine analgesia but failure to alter reactivity to pain in the formalin test, Life Sci., 22, 295, 10.1016/0024-3205(78)90136-4 Rall, 1990, Hypnotics and sedatives: ethanol, 345 Randrup, 1966, Role of catecholamines in the amphetamine excitatory response, Nature, 211, 540, 10.1038/211540a0 Rodríguez Echandía, 1983, Effect of serotonergic and catecholaminergic antagonists on mild stress-induced excessive grooming in the rat, Behav. Neurosci., 97, 1022, 10.1037/0735-7044.97.6.1022 Rosland, 1990, The formalin test in mice: effect of formalin concentration, Pain, 42, 235, 10.1016/0304-3959(90)91167-H Schmidt, 1979, Heat, cold and inflammation, Zeit. Rheumatol., 38, 391 Skaburskis, 1980, Amphetamine-Induced Analgesia in the Formalin Test: Antagonism by Pimozide, a Dopamine Blocker Sulser, 1968, The relative role of storage and synthesis of brain norepinepherine in the psychomotor stimulation evoked by amphetamine or by desipramine and tetrabenazine, Psychopharmacologia, 12, 322, 10.1007/BF00401410 Sutton, 1982, Corticotropin releasing factor produces behavioural activation in rats, Nature, 297, 331, 10.1038/297331a0 Tjølsen, 1991, Lesions of bulbo-spinal serotonergic or noradrenergic pathways reduce nociception as measured by the formalin test, Acta Physiol. Scand., 142, 229, 10.1111/j.1748-1716.1991.tb09151.x Tjølsen, 1992, The formalin test: an evaluation of the method, Pain, 51, 5, 10.1016/0304-3959(92)90003-T Wheeler-Aceto, 1991, Standardization of the rat paw formalin test for the evaluation of analgesics, Psychopharmacology, 104, 35, 10.1007/BF02244551 Willer, 1981, Stress-induced analgesia in humans: endogenous opioids and naloxone-reversible depression of pain reflexes, Science, 212, 689, 10.1126/science.6261330 Woolf, 1991, Common patterns of plasticity contributing to nociceptive sensitization in mammals and aplysia, TINS, 14, 74 Zimmerman, 1983, Ethical guidelines for investigation of experimental pain in conscious animals, Pain, 6, 109, 10.1016/0304-3959(83)90201-4