Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

Arnoult, 2002, Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli, J. Cell Biol., 159, 923, 10.1083/jcb.200207071 Beckman, 1991, The double-edged role of nitric oxide in brain function and superoxide-mediated injury, J. Dev. Physiol., 15, 53 Beckman, 1993, Pathological implications of nitric oxide, superoxide and peroxynitrite formation, Biochem. Soc. Trans., 21, 330, 10.1042/bst0210330 Benjamin, 1980, ADP-ribosylation in mammalian cell ghosts. Dependence of poly(ADP-ribose) synthesis on strand breakage in DNA, J. Biol. Chem., 255, 10493, 10.1016/S0021-9258(19)70490-6 Borner, 1999, Apoptosis without caspases, Cell Death Differ., 6, 497, 10.1038/sj.cdd.4400525 Bowes, 1998, Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts, Br. J. Pharmacol., 124, 1760, 10.1038/sj.bjp.0702009 Braun, 2001, Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus, J. Infect. Dis., 184, 1300, 10.1086/324013 Braun, 2002, Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis, J. Clin. Invest., 109, 19, 10.1172/JCI12035 Burkart, 1999, Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin, Nat. Med., 5, 314, 10.1038/6535 Castilho, 1998, Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells, J. Neurosci., 18, 10277, 10.1523/JNEUROSCI.18-24-10277.1998 Chiarugi, 2002, Cell biology. PARP-1—a perpetrator of apoptotic cell death, Science, 297, 200, 10.1126/science.1074592 Cosi, 1996, Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse, Brain Res., 735, 343, 10.1016/0006-8993(96)00918-3 Cosi, 1996, Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice, Brain Res., 729, 264 Cosi, 1998, Decreases in mouse brain NAD+ and ATP induced by 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP), Brain Res., 809, 58, 10.1016/S0006-8993(98)00829-4 Cosi, 1994, Poly(ADP-ribose) polymerase, J. Neurosci. Res., 39, 38, 10.1002/jnr.490390106 Cregan, 2002, Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death, J. Cell Biol., 158, 507, 10.1083/jcb.200202130 Daugas, 2000, Apoptosis-inducing factor (AIF), FEBS Lett., 476, 118, 10.1016/S0014-5793(00)01731-2 Daugas, 2000, Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis, FASEB J., 14, 729, 10.1096/fasebj.14.5.729 Davidovic, 2001, Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism, Exp. Cell Res., 268, 7, 10.1006/excr.2001.5263 Dawson, 1993, Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures, J. Neurosci., 13, 2651, 10.1523/JNEUROSCI.13-06-02651.1993 Dawson, 1991, Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures, Proc. Natl. Acad. Sci. USA, 88, 6368, 10.1073/pnas.88.14.6368 Dawson, 1996, Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice, J. Neurosci., 16, 2479, 10.1523/JNEUROSCI.16-08-02479.1996 de Murcia, 1994, Poly(ADP-ribose) polymerase, Trends Biochem. Sci., 19, 172, 10.1016/0968-0004(94)90280-1 de Murcia, 1994, Structure and function of poly(ADP-ribose) polymerase, Mol. Cell. Biochem., 138, 15, 10.1007/BF00928438 Ding, 2001, Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment, Brain Res., 915, 210, 10.1016/S0006-8993(01)02852-9 Ducrocq, 2000, Poly(ADP- ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain, J. Neurochem., 74, 2504, 10.1046/j.1471-4159.2000.0742504.x Dumont, 2000, Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes, Blood, 96, 1030, 10.1182/blood.V96.3.1030 Eliasson, 1997, Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia, Nat. Med., 3, 1089, 10.1038/nm1097-1089 Endres, 1997, Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase, J. Cereb. Blood Flow Metab., 17, 1143, 10.1097/00004647-199711000-00002 Ferri, 2000, Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex, J. Exp. Med., 192, 1081, 10.1084/jem.192.8.1081 Fonfria, 2002, Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress, Eur. J. Neurosci., 16, 2013, 10.1046/j.1460-9568.2002.02269.x Genini, 2000, Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria, Blood, 96, 3537, 10.1182/blood.V96.10.3537 Germain, 1999, Cleavage of utomodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7, J. Biol. Chem., 274, 28379, 10.1074/jbc.274.40.28379 Gobeil, 2001, Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1), Cell Death Differ., 8, 588, 10.1038/sj.cdd.4400851 Goto, 2002, Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery, Stroke, 33, 1101, 10.1161/01.STR.0000014203.65693.1E Granville, 2001, Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis, Am. J. Pathol., 159, 305, 10.1016/S0002-9440(10)61696-3 Ha, 1999, Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion, Proc. Natl. Acad. Sci. USA, 96, 13978, 10.1073/pnas.96.24.13978 Ha, 2000, Poly(ADP-ribose) polymerase-1 in the nervous system, Neurobiol. Dis., 7, 225, 10.1006/nbdi.2000.0324 Halappanavar, 1999, Survival and proliferation of cells expressing caspase-uncleavable poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent, J. Biol. Chem., 274, 37097, 10.1074/jbc.274.52.37097 Heller, 1995, Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells, J. Biol. Chem., 270, 11176, 10.1074/jbc.270.19.11176 Hengartner, 2000, The biochemistry of apoptosis, Nature, 407, 770, 10.1038/35037710 Herceg, 1999, Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis, Mol. Cell. Biol., 19, 5124, 10.1128/MCB.19.7.5124 Hisatomi, 2002, Critical role of photoreceptor apoptosis in functional damage after retinal detachment, Curr. Eye Res., 24, 161, 10.1076/ceyr.24.3.161.8305 Hivert, 1998, Hydrogen peroxide-induced motoneuron apoptosis is prevented by poly ADP ribosyl synthetase inhibitors, Neuroreport, 9, 1835, 10.1097/00001756-199806010-00031 Ientile, 2001, Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina, J. Neurochem., 79, 71, 10.1046/j.1471-4159.2001.00532.x Joza, 2001, Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death, Nature, 410, 549, 10.1038/35069004 Kaminker, 2001, TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression, J. Biol. Chem., 276, 35891, 10.1074/jbc.M105968200 Kaufmann, 1993, Specific proteolytic cleavage of poly(ADP-ribose) polymerase, Cancer Res., 53, 3976 Kerr, 1972, Apoptosis, Br. J. Cancer, 26, 239, 10.1038/bjc.1972.33 Klein, 2002, The harlequin mouse mutation downregulates apoptosis-inducing factor, Nature, 419, 367, 10.1038/nature01034 Kruman, 2000, omocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity, J. Neurosci., 20, 6920, 10.1523/JNEUROSCI.20-18-06920.2000 Kukreja, 1992, The oxygen free radical system, Cardiovasc. Res., 26, 641, 10.1093/cvr/26.7.641 LaPlaca, 2001, Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats, J. Neurotrauma, 18, 369, 10.1089/089771501750170912 Lautier, 1993, Molecular and biochemical features of poly (ADP-ribose) metabolism, Mol. Cell. Biochem., 122, 171, 10.1007/BF01076101 Lazebnik, 1994, Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE, Nature, 371, 346, 10.1038/371346a0 Leist, 2001, Four deaths and a funeral, Nat. Rev. Mol. Cell. Biol., 2, 589, 10.1038/35085008 Leist, 1997, The shape of cell death, Biochem. Biophys. Res. Commun., 236, 1, 10.1006/bbrc.1997.6890 Leist, 1997, Apoptosis in the absence of poly-(ADP-ribose) polymerase, Biochem. Biophys. Res. Commun., 233, 518, 10.1006/bbrc.1997.6491 Li, 2001, Endonuclease G is an apoptotic DNase when released from mitochondria, Nature, 412, 95, 10.1038/35083620 Li, 1997, Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade, Cell, 91, 479, 10.1016/S0092-8674(00)80434-1 Lindahl, 1995, Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks, Trends Biochem. Sci., 20, 405, 10.1016/S0968-0004(00)89089-1 Liptay, 2002, Molecular mechanisms of sulfasalazine-induced T-cell apoptosis, Br. J. Pharmacol., 137, 608, 10.1038/sj.bjp.0704870 Lo, 1998, Inhibition of poly(ADP-ribose) polymerase, Stroke, 29, 830, 10.1161/01.STR.29.4.830 Loeffler, 2001, Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor, FASEB J., 15, 758, 10.1096/fj.00-0388com Lynch, 2002, Excitotoxicity, J. Pharmacol. Exp. Ther., 300, 717, 10.1124/jpet.300.3.717 Makani, 2002, Biochemical and molecular basis of thimerosal-induced apoptosis in T cells, Genes Immun., 3, 270, 10.1038/sj.gene.6363854 Mandir, 2000, NMDA but not non-NMDA excitotoxicity is mediated by poly(ADP-ribose) polymerase, J. Neurosci., 20, 8005, 10.1523/JNEUROSCI.20-21-08005.2000 Mandir, 1999, Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism, Proc. Natl. Acad. Sci. USA, 96, 5774, 10.1073/pnas.96.10.5774 Martinou, 2001, Breaking the mitochondrial barrier, Nat. Rev. Mol. Cell. Biol., 2, 63, 10.1038/35048069 Masutani, 1999, Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes, Proc. Natl. Acad. Sci. USA, 96, 2301, 10.1073/pnas.96.5.2301 Mate, 2002, The crystal structure of the mouse apoptosis-inducing factor AIF, Nat. Struct. Biol., 9, 442, 10.1038/nsb793 McGinnis, 1999, Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates, Biochem. Biophys. Res. Commun., 263, 94, 10.1006/bbrc.1999.1315 Menissier-de Murcia, 1989, Zinc-binding domain of poly(ADP-ribose)polymerase participates in the recognition of single strand breaks on DNA, J. Mol. Biol., 210, 229, 10.1016/0022-2836(89)90302-1 Moroni, 2001, Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia, Cell Death Differ., 8, 921, 10.1038/sj.cdd.4400884 Nagayama, 2000, Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia, J. Neurochem., 74, 1636, 10.1046/j.1471-4159.2000.0741636.x Nicotera, 1998, Intracellular ATP, a switch in the decision between apoptosis and necrosis, Toxicol. Lett., 102-103, 139, 10.1016/S0378-4274(98)00298-7 Ohiro, 2002, A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF), FEBS Lett., 524, 163, 10.1016/S0014-5793(02)03049-1 Oliver, 1998, Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant, J. Biol. Chem., 273, 33533, 10.1074/jbc.273.50.33533 Pardo, 2001, A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis, J. Immunol., 167, 1222, 10.4049/jimmunol.167.3.1222 Parrish, 2001, Mitochondrial endonuclease G is important for apoptosis in C. elegans, Nature, 412, 90, 10.1038/35083608 Perez-Galan, 2002, Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia, Leukemia, 16, 2106, 10.1038/sj.leu.2402650 Pieper, 1999, Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes, Proc. Natl. Acad. Sci. USA, 96, 3059, 10.1073/pnas.96.6.3059 Pieper, 2000, Myocardial postischemic injury is reduced by polyADPripose polymerase-1 gene disruption, Mol. Med., 6, 271, 10.1007/BF03401936 Ramachandran, 2001, In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain, Alcohol Clin. Exp. Res., 25, 862, 10.1111/j.1530-0277.2001.tb02292.x Sattler, 2001, Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death, Mol. Neurobiol., 24, 107, 10.1385/MN:24:1-3:107 Schein, 1967, The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity, Cancer Res., 27, 2324 Schreiber, 2002, Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1, J. Biol. Chem., 277, 23028, 10.1074/jbc.M202390200 Sedarous, 2003, Calpains mediate p53 activation and neuronal death evoked by DNA damage, J. Biol. Chem, 278, 26031, 10.1074/jbc.M302833200 Shall, 2000, Poly(ADP-ribose) polymerase-1, Mutat. Res., 460, 1, 10.1016/S0921-8777(00)00016-1 Smith, 2001, The world according to PARP, Trends Biochem. Sci., 26, 174, 10.1016/S0968-0004(00)01780-1 Smulson, 2000, Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1, Adv. Enzyme Regul., 40, 183, 10.1016/S0065-2571(99)00024-2 Stefanis, 1999, Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons, J. Neurosci., 19, 6235, 10.1523/JNEUROSCI.19-15-06235.1999 Stout, 1998, Glutamate-induced neuron death requires mitochondrial calcium uptake, Nat. Neurosci., 1, 366, 10.1038/1577 Susin, 1999, Molecular characterization of mitochondrial apoptosis-inducing factor, Nature, 397, 441, 10.1038/17135 Szabo, 1998, Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion, Trends Pharmacol. Sci., 19, 287, 10.1016/S0165-6147(98)01193-6 Szabo, 1998, Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase, Proc. Natl. Acad. Sci. USA, 95, 3867, 10.1073/pnas.95.7.3867 Takahashi, 1997, Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats, J. Cereb. Blood Flow Metab., 17, 1137, 10.1097/00004647-199711000-00001 Ullrich, 2001, Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1, Nat. Cell Biol., 3, 1035, 10.1038/ncb1201-1035 van Loo, 2001, Endonuclease G, Cell Death Differ., 8, 1136, 10.1038/sj.cdd.4400944 Virag, 2002, The therapeutic potential of poly(ADP-ribose) polymerase inhibitors, Pharmacol. Rev., 54, 375, 10.1124/pr.54.3.375 Wang, 2003, Apoptosis inducing factor and PARP mediated injury in the MPTP mouse model of Parkinson's disease, in: Parkinson's Disease: The Life Cycle of the Dopamine Neuron Annals, New York Academy of Science, New York, 991, 132, 10.1111/j.1749-6632.2003.tb07471.x Wang, 1996, Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury, J. Biol. Chem., 271, 29223, 10.1074/jbc.271.46.29223 Wang, 2002, Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans, Science, 298, 1587, 10.1126/science.1076194 Wang, 1995, Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease, Genes Dev., 9, 509, 10.1101/gad.9.5.509 Whalen, 1999, Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase, J. Cereb. Blood Flow Metab., 19, 835, 10.1097/00004647-199908000-00002 Whitacre, 1995, Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences, Cancer Res., 55, 3697 Wu, 2002, AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis, J. Biol. Chem., 277, 25617, 10.1074/jbc.M202285200 Wyllie, 1980, Cell death, Int. Rev. Cytol., 68, 251, 10.1016/S0074-7696(08)62312-8 Yamamoto, 1981, Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets, Nature, 294, 284, 10.1038/294284a0 Ye, 2002, DNA binding is required for the apoptogenic action of apoptosis inducing factor, Nat. Struct. Biol., 9, 680, 10.1038/nsb836 Ying, 2001, Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death, Proc. Natl. Acad. Sci. USA, 98, 12227, 10.1073/pnas.211202598 Yu, 2002, Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor, Science, 297, 259, 10.1126/science.1072221 Zhang, 1994, Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity, Science, 263, 687, 10.1126/science.8080500 Zhang, 2002, Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite, J. Neurochem., 82, 181, 10.1046/j.1471-4159.2002.00975.x