Obesity reduces the drug survival of second line biological drugs following a first TNF-α inhibitor in rheumatoid arthritis patients

Iannone, 2010, Obesity and inflammation--targets for OA therapy, Curr Drug Targets, 11, 586, 10.2174/138945010791011857 Bhole, 2012, Differences in body mass index among individuals with PsA, psoriasis, RA and the general population, Rheumatology (Oxford), 51, 552, 10.1093/rheumatology/ker349 Crowson, 2013, Contribution of obesity to the rise in incidence of rheumatoid arthritis, Arthritis Care Res (Hoboken), 65, 71, 10.1002/acr.21660 Ajeganova, 2013, Association of obesity with worse disease severity in rheumatoid arthritis as well as with comorbidities: a long-term follow-up from disease onset, Arthritis Care Res (Hoboken), 65, 78, 10.1002/acr.21710 Gremese, 2013, Obesity and reduction of the response rate to anti-tumor necrosis factor α in rheumatoid arthritis: an approach to a personalized medicine, Arthritis Care Res (Hoboken), 65, 94, 10.1002/acr.21768 Choe, 2014, Lack association of body mass index with disease activity composites of rheumatoid arthritis in Korean population: cross-sectional observation, Clin Rheumatol, 33, 485, 10.1007/s10067-013-2427-8 Velpula, 2011, Low body mass index is adversely associated with radiographic joint damage in Indian patients with early rheumatoid arthritis, J Rheumatol, 38, 434, 10.3899/jrheum.100535 Westhoff, 2007, Radiographic joint damage in early rheumatoid arthritis is highly dependent on body mass index, Arthritis Rheum, 56, 3575, 10.1002/art.23033 van der Helm-van Mil, 2008, A high body mass index has a protective effect on the amount of joint destruction in small joints in early rheumatoid arthritis, Ann Rheum Dis, 67, 769, 10.1136/ard.2007.078832 Baker, 2014, Greater body mass independently predicts less radiographic progression on X-ray and MRI over 1–2 years, Ann Rheum Dis, 73, 1923, 10.1136/annrheumdis-2014-205544 Rho, 2009, Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis, Arthritis Rheum, 60, 1906, 10.1002/art.24626 Giles, 2009, Adiponectin is a mediator of the inverse association of adiposity with radiographic damage in rheumatoid arthritis, Arthritis Rheum, 61, 1248, 10.1002/art.24789 Klaasen, 2011, Body mass index and clinical response to infliximab in rheumatoid arthritis, Arthritis Rheum, 63, 359, 10.1002/art.30136 Sandberg, 2014, Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis, Ann Rheum Dis, 73, 2029, 10.1136/annrheumdis-2013-205094 Ellerby, 2014, Obesity and comorbidity are independently associated with a failure to achieve remission in patients with established rheumatoid arthritis, Ann Rheum Dis, 73, e74, 10.1136/annrheumdis-2014-206254 Arnett, 1988, The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis, Arthritis Rheum, 31, 315, 10.1002/art.1780310302 Jacobsson, 2011, New remission criteria for RA: “modern times” in rheumatology--not a silent film, rather a 3D movie, Ann Rheum Dis, 70, 401, 10.1136/ard.2010.145607 Ottaviani, 2012, Body mass index influences the response to infliximab in ankylosing spondylitis, Arthritis Res Ther, 14, R115, 10.1186/ar3841 di Minno, 2013, Obesity and the prediction of minimal disease activity: a prospective study in psoriatic arthritis, Arthritis Care Res (Hoboken), 65, 141, 10.1002/acr.21711 Iannone, 2013, Body mass does not affect the remission of psoriatic arthritis patients on anti-TNF-α therapy, Scand J Rheumatol, 42, 41, 10.3109/03009742.2012.715186 Rodrigues, 2014, A1.1 Obesity is a risk factor for worse treatment response in rheumatoid arthritis patients- results from reuma.pt, Ann Rheum Dis, 73, A1, 10.1136/annrheumdis-2013-205124.1 Heimans, 2013, Association of high body mass index with decreased treatment response to combination therapy in recent-onset rheumatoid arthritis patients, Arthritis Care Res (Hoboken), 65, 1235, 10.1002/acr.21978 Iannone, 2012, Longterm retention of tumor necrosis factor-α inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors, J Rheumatol, 39, 1179, 10.3899/jrheum.111125