Biophysical Properties of Human Medulloblastoma Cells

The Journal of Membrane Biology - Tập 237 Số 2-3 - Trang 59-69 - 2010
Nola Jean Ernest1, Naomi J. Logsdon1, Michael B. McFerrin2, Harald Sontheimer2, Susan Spiller2
1Department of Pediatrics, University of Alabama School of Medicine, 1719 6th Ave. S., CIRC 252A, Birmingham, AL, 35294, USA
2Civitan International Research Center, University of Alabama School of Medicine, Birmingham, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Adamson DC, Shi Q, Wortham M, Northcott PA, Di C, Duncan CG, Li J, McLendon RE, Bigner DD, Taylor MD, Yan H (2010) OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. Cancer Res 70:181–191

Aller MI, Wisden W (2008) Changes in expression of some two-pore domain potassium channel genes (KCNK) in selected brain regions of developing mice. Neuroscience 151:1154–1172

Bloch M, Ousingsawat J, Simon R, Schraml P, Gasser TC, Mihatsch MJ, Kunzelmann K, Bubendorf L (2007) KCNMA1 gene amplification promotes tumor cell proliferation in human prostate cancer. Oncogene 26:2525–2534

Brickley SG, Aller MI, Sandu C, Veale EL, Alder FG, Sambi H, Mathie A, Wisden W (2007) TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. J Neurosci 27:9329–9340

Cambien B, Rezzonico R, Vitale S, Rouzaire-Dubois B, Dubois JM, Barthel R, Karimdjee BS, Mograbi B, Schmid-Alliana A, Schmid-Antomarchi H (2008) Silencing of hSlo potassium channels in human osteosarcoma cells promotes tumorigenesis. Int J Cancer 123:365–371

Codina C, Kraft R, Pietsch T, Prinz M, Steinhauser C, Cervos-Navarro J, Patt S (2000) Voltage- and gamma-aminobutyric acid–activated membrane currents in the human medulloblastoma cell line MHH-MED-3. Neurosci Lett 287:53–56

Di C, Liao S, Adamson DC, Parrett TJ, Broderick DK, Shi Q, Lengauer C, Cummins JM, Velculescu VE, Fults DW, McLendon RE, Bigner DD, Yan H (2005) Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid. Cancer Res 65:919–924

Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85–100

Han J, Truell J, Gnatenco C, Kim D (2002) Characterization of four types of background potassium channels in rat cerebellar granule neurons. J Physiol 542:431–444

Han X, Wang F, Yao W, Xing H, Weng D, Song X, Chen G, Xi L, Zhu T, Zhou J, Xu G, Wang S, Meng L, Iadecola C, Wang G, Ma D (2007) Heat shock proteins and p53 play a critical role in K+ channel-mediated tumor cell proliferation and apoptosis. Apoptosis 12:1837–1846

Han X, Xi L, Wang H, Huang X, Ma X, Han Z, Wu P, Ma X, Lu Y, Wang G, Zhou J, Ma D (2008) The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells. Biochem Biophys Res Commun 375:205–209

Hatton BA, Villavicencio EH, Tsuchiya KD, Pritchard JI, Ditzler S, Pullar B, Hansen S, Knoblaugh SE, Lee D, Eberhart CG, Hallahan AR, Olson JM (2008) The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread. Cancer Res 68:1768–1776

Hockberger PE, Hsiu-Yu T, Connor JA (1987) Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures. J Neurosci 7:1370–1383

Kunzelmann K (2005) Ion channels and cancer. J Membr Biol 205:159–173

Latour I, Louw DF, Beedle AM, Hamid J, Sutherland GR, Zamponi GW (2004) Expression of T-type calcium channel splice variants in human glioma. Glia 48:112–119

Liu X, Chang Y, Reinhart PH, Sontheimer H, Chang Y (2002) Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. J Neurosci 22:1840–1849

Mathie A, Veale EL (2007) Therapeutic potential of neuronal two-pore domain potassium-channel modulators. Curr Opin Investig Drugs 8:555–562

Mathie A, Clarke CE, Ranatunga KM, Veale EL (2003) What are the roles of the many different types of potassium channel expressed in cerebellar granule cells? Cerebellum 2:11–25

Mu D, Chen L, Zhang X, See LH, Koch CM, Yen C, Tong JJ, Spiegel L, Nguyen KC, Servoss A, Peng Y, Pei L, Marks JR, Lowe S, Hoey T, Jan LY, McCombie WR, Wigler MH, Powers S (2003) Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell 3:297–302

Panner A, Wurster RD (2006) T-type calcium channels and tumor proliferation. Cell Calcium 40:253–259

Pardo LA, Contreras-Jurado C, Zientkowska M, Alves F, Stuhmer W (2005) Role of voltage-gated potassium channels in cancer. J Membr Biol 205:115–124

Patel AJ, Lazdunski M (2004) The 2P-domain K+ channels: role in apoptosis and tumorigenesis. Pflugers Arch 448:261–273

Portzehl H, Caldwell PC, Rueegg JC (1964) The dependence of contraction and relaxation of muscle fibres from the crab Maia squinado on the internal concentration of free calcium ions. Biochim Biophys Acta 79:581–591

Radden E, Behrens M, Pehlemann FW, Schmidtmayer J (1994) A novel method for recording whole-cell and single-channel currents from differentiating cerebellar granule cells in situ. Exp Physiol 7:495–504

Ransom CB, Sontheimer H (2001) BK channels in human glioma cells. J Neurophysiol 85:790–803

Schuller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL (2008) Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell 14:123–134

Sontheimer H (2008) An unexpected role for ion channels in brain tumor metastasis. Exp Biol Med 233:779–791

Sontheimer H, Waxman SG (1993) Expression of voltage-activated ion channels by astrocytes and oligodendrocytes in the hippocampal slice. J Neurophysiol 70:1863–1873

Szabo I, Adams C, Gulbins E (2004) Ion channels and membrane rafts in apoptosis. Pflugers Arch 448:304–312

Wang Z (2004) Roles of K+ channels in regulating tumour cell proliferation and apoptosis. Pflugers Arch 448:274–286

Zhang L, Zou W, Zhou SS, Chen DD (2009) Potassium channels and proliferation and migration of breast cancer cells. Sheng Li Xue Bao 61:15–20

Zhou Q, Kwan HY, Chan HC, Jiang JL, Tam SC, Yao X (2003) Blockage of voltage-gated K+ channels inhibits adhesion and proliferation of hepatocarcinoma cells. Int J Mol Med 11:261–266