Effects of DNA methylation on DNA-binding proteins and gene expression

Current Opinion in Genetics & Development - Tập 3 - Trang 226-231 - 1993
Peri H. Tate1, Adrian P. Bird1
1Institute of Cell and Molecular Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JR. Scotland

Tài liệu tham khảo

Li, 1992, Targeted Mutation of the DNA Methyltransferase Gene Results in Embryonic Lethality, Cell, 69, 915, 10.1016/0092-8674(92)90611-F Kafri, 1992, Developmental Pattern of Gene-specific DNA Methylation in the Mouse Embryo and Germ Line, Genes Dev, 6, 705, 10.1101/gad.6.5.705 Monk, 1987, Temporal and Regional Changes in DNA Methylation in the Embryonic, Extraembryonic and Germ Cell Lineages during Mouse Embryo Development, Development, 99, 371, 10.1242/dev.99.3.371 Pfeifer, 1990, In Vivo Footprint and Methylation Analysis by PCR-aided Genomic Sequencing: Comparison of Active and Inactive X Chro mosomal DNA at the CpG Island and Promoter of Human PGK-1, Genes Dev, 4, 1277, 10.1101/gad.4.8.1277 Wolf, 1984, Methylation of the Hypoxanthine Phosphoribosyltmnsferase Locus on the Human X Chromosome: Implications for X chromosome Inactivation, 81, 2806 Riggs, 1992, X-chromosome Inactivation and Cell Memory, Trends Genet, 8, 169, 10.1016/0168-9525(92)90219-T Hadchouel, 1987, Maternal Inhibition of Hepatitis B Surface Antigen Gene Expression in Transgenc Mice Correlates with de novo Methylation, Nature, 329, 454, 10.1038/329454a0 Swain, 1987, Parental Legacy Determines Methylation and Expression of an Autosomal Transgene: A Molecular Mechanism for Parental Imprinting, Cell, 50, 719, 10.1016/0092-8674(87)90330-8 Sasaki, 1992, Parental Imprinting: Potentially Active Chromatin of the Repressed Maternal Allele of the Mouse Insulin-like Growth Factor II Igf2 ) Gene, Genes Dev, 6, 1843, 10.1101/gad.6.10.1843 Cedar, 1988, DNA Methylation and Gene Activity, Cell, 53, 3, 10.1016/0092-8674(88)90479-5 Opdecamp, 1992, Methylation of an Alpha-foetoprotein Gene Intragenic Site Modulates Gene Activity, Nucleic Acids Res, 20, 171, 10.1093/nar/20.2.171 Jansson, 1992, Methylation of Discrete Sites Within the Enhancer Region Regulates the Activity of the Epstein-Barr Virus BamHI W Promoter in Burkitt Lymphoma Lines, J Virol, 66, 62, 10.1128/JVI.66.1.62-69.1992 Guenette, 1992, DNA Methylation Inhibits Transcription of Procollagen Alpha2 I) Promoters, Biochem J, 283, 699, 10.1042/bj2830699 Nyce, 1991, Gene Silencing in Mammalian Cells by Direct Incorporation of Electroporated 5-Methyl-2′-Deoxycytidine 5′-Triphosphate, Somat Cell Mol Genet, 17, 543, 10.1007/BF01233619 Holliday, 1991, Gene Silencing in Mammalian Cells by Uptake of 5-Methyl Deoxycytidine-5′-Triphosphate, Somat Cell Mol Genet, 17, 537, 10.1007/BF01233618 Pfeifer, 1990, Polymerase Chain Reaction-aided Genomic Sequencing of an X Chromosome-linked CpG Island: Methylation Pat terns Suggest Clonal Inheritance, CpG Site Autonomy, and an Explanation of Activity State Stability, 87, 8252 Saluz, 1986, Genomic Sequencing Reveals a Positive Correlation Between the Kinetics of Strand-Specific DNA Demethylation of the Overlapping Estradiol/Glucocorticoid-receptor Binding Sites and the Rate of Avian Vitellogenin mRNA Synthesis, 83, 7167 Frommer, 1992, A Genomic Sequencing Protocol that Yields a Positive Display of 5-methylcytosine Residues in Individual DNA Strands, 89, 1827 Renbaum, 1990, Cloning, Characterisation, and Expression in Escherichia coli of the Gene Coding for the CpG DNA Methylase from Spiroplasma sp. Strain MQ1 M.Sssl), Nucleic Acids Res, 18, 1145, 10.1093/nar/18.5.1145 Weih, 1991, Analysis of CpG Methylation and Genomic Footprinting at the Tyrosine Aminotransferase gene: DNA Methylation Alone is not Sufficient to Prevent Protein Binding in Vivo, EMBO J, 10, 2559, 10.1002/j.1460-2075.1991.tb07796.x Hengst-Zhang, 1992, Methylation Inhibits the Interaction of DNA Binding Proteins with a Potential c-abl Intron Regulatory Element, Biocbem Biophys Res Comm, 186, 1515, 10.1016/S0006-291X(05)81578-5 Van Wijnen, 1992, Overlapping and CpG Methylation-sensitive Protein-DNA Interactions at the Histone H4 Transcriptional Cell Cy cle Domain: Distinctions Between Two Human H4 Gene Promoters, Mol Cell Biol, 12, 3273, 10.1128/MCB.12.7.3273 Lamb, 1991, CpG Methylation of an Endogenous Retroviral Enhancer Inhibits Transcription Factor Binding and Activity, Gene Expr, 1, 186 Larsen, 1992, CpG Islands as Gene Markers in the Human Genome, Genomcs, 13, 1 Boyes, 1991, DNA Methylation Inhibits Transcription Indirectly Via a Methyl-CpG Binding Protein, Cell, 64, 1123, 10.1016/0092-8674(91)90267-3 Boyes, 1992, Repression of Genes by DNA Methylation Depends on CpG Density and Promoter Strength: Evidence for Involvement of a Methyl-CpG Binding Protein, EMBO J, 11, 327, 10.1002/j.1460-2075.1992.tb05055.x Lewis, 1992, Purification, Sequence, and Cellular Localization of a Novel Chromosomal Protein that Binds to Methylated DNA, Cell, 69, 905, 10.1016/0092-8674(92)90610-O Meehan, 1992, Characterization of MeCP2, a Vertebrate DNA Binding Protein with Affinity for Methylated DNA, Nucleic Acids Res, 20, 5085, 10.1093/nar/20.19.5085 Bird, 1992, The Essentials of DNA Methylation, Cell, 70, 5, 10.1016/0092-8674(92)90526-I Hsieh, 1992, CpG Methylated Minichromosomes Become Inaccessible for V D)J Recombination After Undergoing Replication, EMBO J, 11, 315, 10.1002/j.1460-2075.1992.tb05054.x Supakar, 1988, Methylated DNA-binding Protein is Present in Various Mammalian Cell Types, Nucleic Acids Res, 16, 8029, 10.1093/nar/16.16.8029 Pawlak, 1991, An Avian 40 KDa Nucleoprotein Binds Preferentially to a Promoter Sequence Containing One Single Pair of Methylated CpG, Nucleic Acicds Res, 19, 1029, 10.1093/nar/19.5.1029 Jost, 1991, Estradiol Down Regulates the Binding Activity of an Avian Vitellogenin Gene Repressor MDBP-2) and Triggers a Gradual Demethylation of the mCpG Pair of its DNA Binding Site, Nucleic Acids Res, 19, 5771, 10.1093/nar/19.20.5771 Jost, 1992, The Repressor MDBP-2 is a Member of the Histone H 1 Family that Binds Preferentially in Vitro and in Vivo to Methylated Nonspecific DNA Sequences, 89, 9499 Higurashi, 1992, The Combination of DNA Methylation and H1 Histone Binding Inhibits the Action of a Restriction Nuclease on Plasmid DNA, J Biol Gem, 266, 8619 Ball, 1983, 5-Methylcytosine is Localized in Nucleosomes that Contain Historic HI, 80, 5490 Murray, 1987, Site Specific Demethylation in the Promoter of Human Gamma-Globin Gene Does Not Alleviate Methylation Mediated Suppression, EMBO J, 6, 2329, 10.1002/j.1460-2075.1987.tb02508.x Klages, 1992, The Involvement of Demethylation in the Myeloid-specific Function of the Mouse M Lysozyme Gene Downstream Enhancer, Nucleic Acid; Res, 20, 1925, 10.1093/nar/20.8.1925 Choi, 1991, DNA Hypomethylation and Germ Cell specific Expression of Testis-specific H2B Histone Gene, J Biol Chem, 266, 20504, 10.1016/S0021-9258(18)54953-X Comb, 1990, CpG Methylation Inhibits Proenkephalin Gene Expression and Binding of the Transcription Factor AP-2, Nucleic Acids Res, 18, 3975, 10.1093/nar/18.13.3975 Prendergast, 1991, Association of Myn, the Murine Homolog of max, with c-myc Stimulates Methylation-sensitive DNA Binding and ras Cotransformation, Cell, 65, 395, 10.1016/0092-8674(91)90457-A Iguchi-Ariga, 1989, CpG Methylation of the CAMP-responsive Enhancer/Promoter Sequence TGAC-GTCA Abolishes Specific Factor Binding as Well as Transcriptional Activation, Genes Dev, 3, 612, 10.1101/gad.3.5.612 Faizon, 1991, Binding of the Transcription Factor EBP80 Mediates the Methylation Response of an Intracisternal A-Particle Long Terminal Repeat Promoter, Mol Cell Blol, 11, 117, 10.1128/MCB.11.1.117 Kovesdi, 1987, Role of an Adenovirus E2 Promoter Binding Factor in EIA-Mediated Coordinate Gene Control, 84, 2180 Inamdar, 1991, CpG Methylation Inhibits Binding of Several Sequence-specific DNA-binding Proteins from Pea, Wheat, Soybean and Cauliflower, Plant Mol Biol, 17, 111, 10.1007/BF00036811 Watt, 1988, Cytosine Methylation Prevents Binding to DNA of a HeLa Cell Transcription Factor Required for Optimal Expression of the Adenovirus Major Late Promoter, Genes Dev, 2, 1136, 10.1101/gad.2.9.1136 Bednarik, 1991, DNA CpG Methylation Inhibits Binding of NF-kappa B Proteins to the HIV-1 Long Terminal Repeat Cognate DNA Motifs, N Biol, 3, 969 Ben-Hattar, 1989, Cytosine Methylation in CTF and Spl Recognition Sites of an HSV tk Promoter: Effects on Transcription in Vivo and on Factor Binding in Vitro, Nucleic Acids Res, 17, 10179, 10.1093/nar/17.24.10179 Ehrlich, 1992, A Broad Bean cDNA Clone Encoding a DNA-Binding Protein Resembling Mammalian CREB in its Sequence Specificity and DNA Methylation Sensitivity, Gene, 117, 169, 10.1016/0378-1119(92)90726-6 Holler, 1988, Sp1 Transcription Factor Binds DNA and Activates Transcription Even When the Binding Site is CpG Methylated, Genes Dev, 2, 1127, 10.1101/gad.2.9.1127 Harrington, 1988, Cytosine Methylation Does Not Affect Binding of Transcription Factor Spl, 85, 2066 Lee, 1992, Isolation and Characterization of Nuclear Proteins that Bind to T Cell Receptor V Beta Decamer Motif, J Immunol, 148, 1906, 10.4049/jimmunol.148.6.1906 Meehan, 1989, Identification of a Mammalian Protein that Binds Specifically to DNA Containing Methylated CpGs, Cell, 58, 499, 10.1016/0092-8674(89)90430-3 Zhang, 1989, A Plant DNAbinding Protein that Recognizes 5-Methylcytosine Residues, Mol Cell Biol, 9, 1351, 10.1128/MCB.9.3.1351 Ehrlich, 1990, Highly Repeated Sites in the Apolipoprotein a) Gene Recognized by Methylated DNABinding Protein, a Sequence-Specific DNA-Binding Protein, Mol Cell Biol, 10, 4957, 10.1128/MCB.10.9.4957