Atomic Force Microscopy Studies of Functional and Dysfunctional Pulmonary Surfactant Films. I. Micro- and Nanostructures of Functional Pulmonary Surfactant Films and the Effect of SP-A

Biophysical Journal - Tập 94 - Trang 3549-3564 - 2008
Yi Y. Zuo1,2,3, Eleonora Keating1, Lin Zhao3, Seyed M. Tadayyon1, Ruud A.W. Veldhuizen4, Nils O. Petersen1,2,5, Fred Possmayer2,3
1Department of Chemistry, University of Western Ontario, London, Ontario Canada
2Department of Biochemistry, University of Western Ontario, London, Ontario Canada
3Department of Obstetrics and Gynaecology, University of Western Ontario, London, Ontario, Canada
4Departments of Physiology and Pharmacology and Medicine, University of Western Ontario, London, Ontario, Canada
5National Institute for Nanotechnology, National Research Council Canada, Edmonton, Alberta, Canada

Tài liệu tham khảo

Possmayer, 2004, Physicochemical aspects of pulmonary surfactant, 1014 Rodriguez-Capote, 2001, Surfactant protein interactions with neutral and acidic phospholipid films, Am. J. Physiol. Lung Cell. Mol. Physiol., 281, L231, 10.1152/ajplung.2001.281.1.L231 Takamoto, 2001, Interaction of lung surfactant proteins with anionic phospholipids, Biophys. J., 81, 153, 10.1016/S0006-3495(01)75688-3 Biswas, 2007, Differential effects of lysophosphatidylcholine on the adsorption of phospholipids to an air/water interface, Biophys. J., 92, 493, 10.1529/biophysj.106.089623 Seifert, 2007, Solubility versus electrostatics: what determines lipid/protein interaction in lung surfactant, Biophys. J., 93, 1192, 10.1529/biophysj.107.106765 Zuo, 2007, How does pulmonary surfactant reduce surface tension to very low values?, J. Appl. Physiol., 102, 1733, 10.1152/japplphysiol.00187.2007 Schurch, 1982, Surface tension at low lung volumes: dependence on time and alveolar size, Respir. Physiol., 48, 339, 10.1016/0034-5687(82)90038-X Gaines, 1966 Veldhuizen, 1998, The role of lipids in pulmonary surfactant, Biochim. Biophys. Acta, 1408, 90, 10.1016/S0925-4439(98)00061-1 Postle, 2001, A comparison of the molecular species compositions of mammalian lung surfactant phospholipids, Comp. Biochem. Physiol. A Mol. Integr. Physiol., 129, 65, 10.1016/S1095-6433(01)00306-3 Watkins, 1968, The surface properties of pure phospholipids in relation to those of lung extracts, Biochim. Biophys. Acta, 152, 293, 10.1016/0005-2760(68)90037-4 Clements, 1977, Functions of the alveolar lining, Am. Rev. Respir. Dis., 115, 67 Bangham, 1979, The physical properties of an effective lung surfactant, Biochim. Biophys. Acta, 573, 552, 10.1016/0005-2760(79)90229-7 Discher, 1996, Lateral phase separation in interfacial films of pulmonary surfactant, Biophys. J., 71, 2583, 10.1016/S0006-3495(96)79450-X von Nahmen, 1997, The phase behavior of lipid monolayers containing pulmonary surfactant protein C studied by fluorescence light microscopy, Eur. Biophys. J., 26, 359, 10.1007/s002490050090 Nag, 1998, Phase transitions in films of lung surfactant at the air-water interface, Biophys. J., 74, 2983, 10.1016/S0006-3495(98)78005-1 Lipp, 1997, Fluorescence, polarized fluorescence, and Brewster angle microscopy of palmitic acid and lung surfactant protein B monolayers, Biophys. J., 72, 2783, 10.1016/S0006-3495(97)78921-5 Discher, 1999, Phase separation in monolayers of pulmonary surfactant phospholipids at the air-water interface: composition and structure, Biophys. J., 77, 2051, 10.1016/S0006-3495(99)77046-3 Piknova, 2001, Discrepancy between phase behavior of lung surfactant phospholipids and the classical model of surfactant function, Biophys. J., 81, 2172, 10.1016/S0006-3495(01)75865-1 Amrein, 1997, A scanning force- and fluorescence light microscopy study of the structure and function of a model pulmonary surfactant, Eur. Biophys. J., 26, 349, 10.1007/s002490050089 von Nahmen, 1997, The structure of a model pulmonary surfactant as revealed by scanning force microscopy, Biophys. J., 72, 463, 10.1016/S0006-3495(97)78687-9 Ding, 2001, Effects of lung surfactant proteins, SP-B and SP-C, and palmitic acid on monolayer stability, Biophys. J., 80, 2262, 10.1016/S0006-3495(01)76198-X Bourdos, 2000, Analysis of lung surfactant model systems with time-of-flight secondary ion mass spectrometry, Biophys. J., 79, 357, 10.1016/S0006-3495(00)76297-7 Harbottle, 2003, Molecular organization revealed by time-of-flight secondary ion mass spectrometry of a clinically used extracted pulmonary surfactant, Langmuir, 19, 3698, 10.1021/la026350b Keating, 2007, Effect of cholesterol on the biophysical and physiological properties of a clinical pulmonary surfactant, Biophys. J., 93, 1391, 10.1529/biophysj.106.099762 Grunder, 1999, Structures of surfactant films: a scanning force microscopy study, Eur. Respir. J., 14, 1290, 10.1183/09031936.99.14612909 Kaganer, 1999, Structure and phase transitions in Langmuir monolayers, Rev. Mod. Phys., 71, 779, 10.1103/RevModPhys.71.779 Possmayer, 2001, Surface activity in vitro: role of surfactant proteins, Comp. Biochem. Physiol. A Mol. Integr. Physiol., 129, 209, 10.1016/S1095-6433(01)00317-8 McCormack, 1998, Structure, processing and properties of surfactant protein A, Biochim. Biophys. Acta, 1408, 109, 10.1016/S0925-4439(98)00062-3 Voss, 1988, Macromolecular organization of natural and recombinant lung surfactant protein SP 28–36. Structural homology with the complement factor C1q, J. Mol. Biol., 201, 219, 10.1016/0022-2836(88)90448-2 Casals, 2001, Role of surfactant protein A (SP-A)/lipid interactions for SP-A functions in the lung, Pediatr. Pathol. Mol. Med., 20, 249, 10.1080/15513810109168821 Williams, 1991, Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C, Am. J. Respir. Cell Mol. Biol., 5, 41, 10.1165/ajrcmb/5.1.41 Veldhuizen, 1996, Surfactant-associated protein A is important for maintaining surfactant large-aggregate forms during surface-area cycling, Biochem. J., 313, 835, 10.1042/bj3130835 Chung, 1989, Effect of surfactant-associated protein-A (SP-A) on the activity of lipid extract surfactant, Biochim. Biophys. Acta, 1002, 348, 10.1016/0005-2760(89)90349-4 Schurch, 1992, Pulmonary SP-A enhances adsorption and appears to induce surface sorting of lipid extract surfactant, Am. J. Physiol., 263, L210 Connell, 2006, The atomic force microscope as a tool for studying phase separation in lipid membranes, Mol. Membr. Biol., 23, 17, 10.1080/09687860500501158 Chi, 1993, Domain structures in Langmuir-Blodgett films investigated by atomic force microscopy, Science, 259, 213, 10.1126/science.259.5092.213 Yu, 1983, Bovine pulmonary surfactant: chemical composition and physical properties, Lipids, 18, 522, 10.1007/BF02535391 Yu, 1987, Characterization of the small hydrophobic proteins associated with pulmonary surfactant, Biochim. Biophys. Acta, 921, 437, 10.1016/0005-2760(87)90070-1 Rodriguez-Capote, 2003, Pulmonary surfactant protein-A (SP-A) restores the surface properties of surfactant after oxidation by a mechanism that requires the Cys6 interchain disulfide bond and the phospholipid binding domain, J. Biol. Chem., 278, 20461, 10.1074/jbc.M212697200 Bligh, 1959, A rapid method of total lipid extraction and purification, Can. J. Biochem. Physiol., 37, 911, 10.1139/y59-099 Haagsman, 1989, Studies of the structure of lung surfactant protein SP-A, Am. J. Physiol., 257, L421 Bailey, 2006, Physiological effects of oxidized exogenous surfactant in vivo: effects of high tidal volume and surfactant protein A, Am. J. Physiol. Lung Cell. Mol. Physiol., 291, L703, 10.1152/ajplung.00538.2005 Lowry, 1951, Protein measurement with the Folin reagent, J. Biol. Chem., 193, 265, 10.1016/S0021-9258(19)52451-6 Zasadzinski, 1994, Langmuir-Blodgett films, Science, 263, 1726, 10.1126/science.8134836 Marsh, 1990 Piknova, 2002, Pulmonary surfactant: phase behavior and function, Curr. Opin. Struct. Biol., 12, 487, 10.1016/S0959-440X(02)00352-4 Ruano, 2000, Self-aggregation of surfactant protein A, Biochemistry, 39, 6529, 10.1021/bi000188z Palaniyar, 1998, Surfactant protein A (SP-A) forms a novel supraquaternary structure in the form of fibers, Biochem. Biophys. Res. Commun., 250, 131, 10.1006/bbrc.1998.9284 Ruano, 1998, Differential partitioning of pulmonary surfactant protein SP-A into regions of monolayers of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylcholine/dipalmitoylphosphatidylglycerol, Biophys. J., 74, 1101, 10.1016/S0006-3495(98)77828-2 Worthman, 2000, Pulmonary surfactant protein A interacts with gel-like regions in monolayers of pulmonary surfactant lipid extract, Biophys. J., 79, 2657, 10.1016/S0006-3495(00)76504-0 Krol, 2000, Formation of three-dimensional protein-lipid aggregates in monolayer films induced by surfactant protein B, Biophys. J., 79, 904, 10.1016/S0006-3495(00)76346-6 Hollars, 1998, Submicron structures in I-alpha dipalmitoylphosphatidylcholine monolayers and bilayers probed with confocal, atomic force and near field microscopy, Biophys. J., 75, 342, 10.1016/S0006-3495(98)77518-6 Cruz, 2004, Effect of pulmonary surfactant protein SP-B on the micro- and nanostructure of phospholipid films, Biophys. J., 86, 308, 10.1016/S0006-3495(04)74106-5 Cruz, 2005, Influence of a fluorescent probe on the nanostructure of phospholipid membranes: dipalmitoylphosphatidylcholine interfacial monolayers, Langmuir, 21, 5349, 10.1021/la046759w Perez-Gil, 2002, Molecular interactions in pulmonary surfactant films, Biol. Neonate., 81, 6, 10.1159/000056765 Discher, 1999, Neutral lipids induce critical behavior in interfacial monolayers of pulmonary surfactant, Biochemistry, 38, 374, 10.1021/bi981386h Benvegnu, 1992, Line tension between liquid domains in lipid monolayers, J. Phys. Chem., 96, 6820, 10.1021/j100195a053 Discher, 2002, Effect of neutral lipids on coexisting phases in monolayers of pulmonary surfactant, Biophys. Chem., 101–102, 333, 10.1016/S0301-4622(02)00191-6 McConnell, 1988, Shapes of finite two-dimensional lipid domains, J. Phys. Chem., 92, 4520, 10.1021/j100326a053 McConnell, 1991, Structures and transitions in lipid monolayers at the air-water interface, Annu. Rev. Phys. Chem., 42, 171, 10.1146/annurev.pc.42.100191.001131 McConnell, 1996, Equilibration rates in lipid monolayers, Proc. Natl. Acad. Sci. USA, 93, 15001, 10.1073/pnas.93.26.15001 Klopfer, 1996, Isotherms of dipalmitoylphosphatidylcholine (DPPC) monolayers: Features revealed and features obscured, J. Colloid Interface Sci., 182, 220, 10.1006/jcis.1996.0454 Taneva, 1994, Pulmonary surfactant proteins SP-B and SP-C in spread monolayers at the air-water interface: III. Proteins SP-B plus SP-C with phospholipids in spread monolayers, Biophys. J., 66, 1158, 10.1016/S0006-3495(94)80897-5 Diemel, 2002, Multilayer formation upon compression of surfactant monolayers depends on protein concentration as well as lipid composition. An atomic force microscopy study, J. Biol. Chem., 277, 21179, 10.1074/jbc.M111758200 Nag, 2002, Segregation of saturated chain lipids in pulmonary surfactant films and bilayers, Biophys. J., 82, 2041, 10.1016/S0006-3495(02)75552-5 Wang, 2005, Monolayer-multilayer transitions in a lung surfactant model: IR reflection-absorption spectroscopy and atomic force microscopy, Eur. Biophys. J., 34, 243, 10.1007/s00249-004-0446-8 Keough, 1992, Physical chemistry of pulmonary surfactant in the terminal air spaces, 109 Galla, 1998, The role of pulmonary surfactant protein C during the breathing cycle, Thin Solid Films, 327–329, 632, 10.1016/S0040-6090(98)00728-7 Lipp, 1996, Phase and morphology changes in lipid monolayers induced by SP-B protein and its amino-terminal peptide, Science, 273, 1196, 10.1126/science.273.5279.1196 Zasadzinski, 2001, The physics and physiology of lung surfactants, Curr. Opin. Colloid Interface Sci., 6, 506, 10.1016/S1359-0294(01)00124-8 Kramer, 2000, Distribution of the surfactant-associated protein C within a lung surfactant model film investigated by near-field optical microscopy, Biophys. J., 78, 458, 10.1016/S0006-3495(00)76608-2 Diamant, 2000, Unstable topography of biphasic surfactant monolayers, Europhys. Lett., 52, 171, 10.1209/epl/i2000-00419-1 Diamant, 2001, Topography and instability of monolayers near domain boundaries, Phys. Rev. E Stat. Nonlin. Soft Matter Phys., 63, 061602, 10.1103/PhysRevE.63.061602 Crane, 2001, Rapid compression transforms interfacial monolayers of pulmonary surfactant, Biophys. J., 80, 1863, 10.1016/S0006-3495(01)76156-5 Smith, 2003, Metastability of a supercompressed fluid monolayer, Biophys. J., 85, 3048, 10.1016/S0006-3495(03)74723-7 Marmur, 2004, The Lotus effect: superhydrophobicity and metastability, Langmuir, 20, 3517, 10.1021/la036369u Lau, 2003, Superhydrophobic carbon nanotube forests, Nano Lett., 3, 1701, 10.1021/nl034704t Lee, 2004, Nanostructuring of a polymeric substrate with well-defined nanometer-scale topography and tailored surface wettability, Langmuir, 20, 7665, 10.1021/la049411+ Lipp, 1998, Coexistence of buckled and flat monolayers, Phys. Rev. Lett., 81, 1650, 10.1103/PhysRevLett.81.1650 Yu, 1988, Comparative studies on the biophysical activities of the low-molecular-weight hydrophobic proteins purified from bovine pulmonary surfactant, Biochim. Biophys. Acta, 961, 337, 10.1016/0005-2760(88)90081-1 Baoukina, 2007, The molecular mechanism of monolayer-bilayer transformations of lung surfactant from molecular dynamics simulations, Biophys. J., 93, 3775, 10.1529/biophysj.107.113399 Knebel, 2002, Scanning force microscopy at the air-water interface of an air bubble coated with pulmonary surfactant, Biophys. J., 82, 474, 10.1016/S0006-3495(02)75412-X Venkitaraman, 1990, Enhancement of biophysical activity of lung surfactant extracts and phospholipid-apoprotein mixtures by surfactant protein A, Chem. Phys. Lipids, 56, 185, 10.1016/0009-3084(90)90101-V Korfhagen, 1996, Altered surfactant function and structure in SP-A gene targeted mice, Proc. Natl. Acad. Sci. USA, 93, 9594, 10.1073/pnas.93.18.9594 Crouch, 2001, Surfactant proteins A and D and pulmonary host defense, Annu. Rev. Physiol., 63, 521, 10.1146/annurev.physiol.63.1.521 Sun, 1997, Biophysical and physiological properties of a modified porcine surfactant enriched with surfactant protein A, Eur. Respir. J., 10, 1967, 10.1183/09031936.97.10091967 Yu, 1994, Effect of pulmonary surfactant protein A (SP-A) and calcium on the adsorption of cholesterol and film stability, Biochim. Biophys. Acta, 1211, 350, 10.1016/0005-2760(94)90160-0 Schurch, 1995, The surface-associated surfactant reservoir in the alveolar lining, Biol. Neonate., 67, 61, 10.1159/000244207 Yu, 1996, Effect of pulmonary surfactant protein A and neutral lipid on accretion and organization of dipalmitoylphosphatidylcholine in surface films, J. Lipid Res., 37, 1278, 10.1016/S0022-2275(20)39157-4 Bernardino de la Serna, 2004, Cholesterol rules: direct observation of the coexistence of two fluid phases in native pulmonary surfactant membranes at physiological temperatures, J. Biol. Chem., 279, 40715, 10.1074/jbc.M404648200 Leonenko, 2007, An elevated level of cholesterol impairs self-assembly of pulmonary surfactant into a functional film, Biophys. J., 93, 674, 10.1529/biophysj.107.106310 Schurch, 1978, Direct determination of volume- and time-dependence of alveolar surface tension in excised lungs, Proc. Natl. Acad. Sci. USA, 75, 3417, 10.1073/pnas.75.7.3417 Bachofen, 2001, Alveolar surface forces and lung architecture, Comp. Biochem. Physiol. A Mol. Integr. Physiol., 129, 183, 10.1016/S1095-6433(01)00315-4