Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer

International Journal of Biological Macromolecules - Tập 122 - Trang 338-347 - 2019
Bhuvaneshwar Vaidya1, Vineela Parvathaneni2, Nishant S. Kulkarni2, Snehal K. Shukla2, Jenna K. Damon3, Apoorva Sarode4, Dipti Kanabar2, Jerome V. Garcia3, Samir Mitragotri4, Aaron Muth2, Vivek Gupta1,2
1School of Pharmacy, Keck Graduate Institute, Claremont, CA 91711, United States of America
2College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, United States of America
3Department of Biology, University of La Verne, La Verne, CA 91750, United States of America
4John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, United States of America

Tài liệu tham khảo

Torre, 2016, Lung cancer statistics, Adv. Exp. Med. Biol., 893, 1, 10.1007/978-3-319-24223-1_1 Cataldo, 2011, Treatment of non-small-cell lung cancer with erlotinib or gefitinib, N. Engl. J. Med., 364, 947, 10.1056/NEJMct0807960 Mandal, 2016, Development and in vitro evaluation of core-shell type lipid-polymer hybrid nanoparticles for the delivery of erlotinib in non-small cell lung cancer, Eur. J. Pharm. Sci., 81, 162, 10.1016/j.ejps.2015.10.021 Shien, 2014, Drug resistance to EGFR tyrosine kinase inhibitors for non-small cell lung cancer, Acta Med. Okayama, 68, 191 Ramasamy, 2017, Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review, J. Control. Release, 258, 226, 10.1016/j.jconrel.2017.04.043 Anselmo, 2013, Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells, ACS Nano, 7, 11129, 10.1021/nn404853z Ramasamy, 2017, Engineering of cell microenvironment-responsive polypeptide nanovehicle co-encapsulating a synergistic combination of small molecules for effective chemotherapy in solid tumors, Acta Biomater., 48, 131, 10.1016/j.actbio.2016.10.034 Ramasamy, 2014, Layer-by-layer assembly of liposomal nanoparticles with PEGylated polyelectrolytes enhances systemic delivery of multiple anticancer drugs, Acta Biomater., 10, 5116, 10.1016/j.actbio.2014.08.021 Kaur, 2013, p300/CBP dependent hyperacetylation of histone potentiates anticancer activity of gefitinib nanoparticles, Biochim. Biophys. Acta, 1833, 1028, 10.1016/j.bbamcr.2013.01.029 Marslin, 2009, Poly(d,l-lactic-co-glycolic acid) nanoencapsulation reduces erlotinib-induced subacute toxicity in rat, J. Biomed. Nanotechnol., 5, 464, 10.1166/jbn.2009.1075 Noorani, 2017, Erlotinib-loaded albumin nanoparticles: a novel injectable form of erlotinib and its in vivo efficacy against pancreatic adenocarcinoma ASPC-1 and PANC-1 cell lines, Int. J. Pharm., 531, 299, 10.1016/j.ijpharm.2017.08.102 Barghi, 2014, Synthesis, characterization and in vitro anti-tumoral evaluation of erlotinib-PCEC nanoparticles, Asian Pac. J. Cancer Prev., 15, 10281, 10.7314/APJCP.2014.15.23.10281 Vrignaud, 2012, Design, optimization and in vitro evaluation of reverse micelle-loaded lipid nanocarriers containing erlotinib hydrochloride, Int. J. Pharm., 436, 194, 10.1016/j.ijpharm.2012.06.026 Fathi, 2017, Folate-conjugated thermosensitive O-maleoyl modified chitosan micellar nanoparticles for targeted delivery of erlotinib, Carbohydr. Polym., 172, 130, 10.1016/j.carbpol.2017.05.007 Xu, 2017, Novel therapeutic modalities and drug delivery - erlotinib liposomes modified with galactosylated lipid: in vitro and in vivo investigations, Artif. Cells Nanomed. Biotechnol., 1, 10.1080/21691401.2017.1396222 Morton, 2014, A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways, Sci. Signal., 7, ra44, 10.1126/scisignal.2005261 Kim, 2017, PEGylated polypeptide lipid nanocapsules to enhance the anticancer efficacy of erlotinib in non-small cell lung cancer, Colloids Surf. B: Biointerfaces, 150, 393, 10.1016/j.colsurfb.2016.11.002 Lam, 2014, Adsorption and desorption of tyrosine kinase inhibitor erlotinib on gold nanoparticles, J. Colloid Interface Sci., 425, 96, 10.1016/j.jcis.2014.03.032 Fathi, 2018, Thermo-sensitive chitosan copolymer-gold hybrid nanoparticles as a nanocarrier for delivery of erlotinib, Int. J. Biol. Macromol., 106, 266, 10.1016/j.ijbiomac.2017.08.020 Gao, 2012, Preparation, characterization and pharmacokinetic studies of tacrolimus-dimethyl-beta-cyclodextrin inclusion complex-loaded albumin nanoparticles, Int. J. Pharm., 427, 410, 10.1016/j.ijpharm.2012.01.054 Onnainty, 2016, Permeability profiles and intestinal toxicity assessment of hydrochlorothiazide and its inclusion complex with beta-cyclodextrin loaded into chitosan nanoparticles, Mol. Pharm., 13, 3736, 10.1021/acs.molpharmaceut.6b00532 Sajeesh, 2006, Cyclodextrin-insulin complex encapsulated polymethacrylic acid based nanoparticles for oral insulin delivery, Int. J. Pharm., 325, 147, 10.1016/j.ijpharm.2006.06.019 Tang, 2017, Dimethyl-beta-cyclodextrin/salazosulfapyridine inclusion complex-loaded chitosan nanoparticles for sustained release, Carbohydr. Polym., 156, 215, 10.1016/j.carbpol.2016.09.038 Gupta, 2011, PLGA microparticles encapsulating prostaglandin E1-hydroxypropyl-beta-cyclodextrin (PGE1-HPbetaCD) complex for the treatment of pulmonary arterial hypertension (PAH), Pharm. Res., 28, 1733, 10.1007/s11095-011-0409-6 Swarnakar, 2013, Effect of co-administration of CoQ10-loaded nanoparticles on the efficacy and cardiotoxicity of doxorubicin-loaded nanoparticles, RSC Adv., 3, 14671, 10.1039/c3ra41107a Preet, 2012, Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity, Int. J. Cancer, 130, 1660, 10.1002/ijc.26158 Baek, 2016, Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time, Onco. Targets Ther., 9, 7207, 10.2147/OTT.S112566 Mohapatra, 2016, Spectral mapping of 3D multi-cellular tumor spheroids: time-resolved confocal microscopy, Phys. Chem. Chem. Phys., 18, 18381, 10.1039/C6CP02748B Devasari, 2015, Inclusion complex of erlotinib with sulfobutyl ether-beta-cyclodextrin: preparation, characterization, in silico, in vitro and in vivo evaluation, Carbohydr. Polym., 134, 547, 10.1016/j.carbpol.2015.08.012 Franken, 2006, Clonogenic assay of cells in vitro, Nat. Protoc., 1, 2315, 10.1038/nprot.2006.339 Heydt, 2018, Novel approaches against epidermal growth factor receptor tyrosine kinase inhibitor resistance, Oncotarget, 9, 15418, 10.18632/oncotarget.24624 Anichini, 2018, The non-small cell lung cancer immune landscape: emerging complexity, prognostic relevance and prospective significance in the context of immunotherapy, Cancer Immunol. Immunother., 67, 1011, 10.1007/s00262-018-2147-7 Riccardi, 2006, Analysis of apoptosis by propidium iodide staining and flow cytometry, Nat. Protoc., 1, 1458, 10.1038/nprot.2006.238 Boulares, 1999, Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells, J. Biol. Chem., 274, 22932, 10.1074/jbc.274.33.22932 Liu, 2017, Role of autophagy and apoptosis in non-small-cell lung cancer, Int. J. Mol. Sci., 18, 10.3390/ijms18020367 Huang, 2015, Nanoparticles modulate autophagic effect in a dispersity-dependent manner, Sci. Rep., 5 Wei, 2017, New findings of silica nanoparticles induced ER autophagy in human colon cancer cell, Sci. Rep., 7 Wang, 2017, Silica nanoparticles induce autophagy dysfunction via lysosomal impairment and inhibition of autophagosome degradation in hepatocytes, Int. J. Nanomedicine, 12, 809, 10.2147/IJN.S123596 Han, 2011, EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells, PLoS One, 6, 10.1371/journal.pone.0018691 Goodman, 2008, 3-D tissue culture systems for the evaluation and optimization of nanoparticle-based drug carriers, Bioconjug. Chem., 19, 1951, 10.1021/bc800233a Wang, 2013, Doxorubicin delivery to 3D multicellular spheroids and tumors based on boronic acid-rich chitosan nanoparticles, Biomaterials, 34, 4667, 10.1016/j.biomaterials.2013.03.008 Sims, 2017, Distribution of PLGA-modified nanoparticles in 3D cell culture models of hypo-vascularized tumor tissue, J. Nanobiotechnol., 15, 67, 10.1186/s12951-017-0298-x