Exercise-Induced Cardiac Remodeling

Henschen, 1899, Skidlauf und Skidwettlauf. Eine medizinische Sportstudie, Mitt Med Klin Upsala, 2 Darling, 1899, The effects of training. A study of the Harvard University crews, Boston Med Surg J, CXLI:229, 10.1056/NEJM189909071411001 Roskamm, 1961, Relations between heart size and physical efficiency in male and female athletes in comparison with normal male and female subjects, Arch Kreislaufforsch, 35, 67, 10.1007/BF02119723 Reindell, 1960, The heart and blood circulation in athletes, Med Welt, 31, 1557 Bulychev, 1965, Roentgenological and instrumental examination of the heart in athletes, Klin Med, 43, 108 Rowell, 1986 Jose, 1970, The normal range and determinants of the intrinsic heart rate in man, Cardiovasc Res, 4, 160, 10.1093/cvr/4.2.160 Uusitalo, 1998, Exhaustive endurance training for 6-9 weeks did not induce changes in intrinsic heart rate and cardiac autonomic modulation in female athletes, Int J Sports Med, 19, 532, 10.1055/s-2007-971956 Maron, 2005, Introduction: eligibility recommendations for competitive athletes with cardiovascular abnormalities—general considerations, J Am Coll Cardiol, 45, 1318, 10.1016/j.jacc.2005.02.006 Roeske, 1976, Noninvasive evaluation of ventricular hypertrophy in professional athletes, Circulation, 53, 286, 10.1161/01.CIR.53.2.286 Pelliccia, 1999, Physiologic left ventricular cavity dilatation in elite athletes, Ann Intern Med, 130, 23, 10.7326/0003-4819-130-1-199901050-00005 Pelliccia, 1991, The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes, N Engl J Med, 324, 295, 10.1056/NEJM199101313240504 Sharma, 2002, Physiologic limits of left ventricular hypertrophy in elite junior athletes: relevance to differential diagnosis of athlete's heart and hypertrophic cardiomyopathy, J Am Coll Cardiol, 40, 1431, 10.1016/S0735-1097(02)02270-2 Baggish, 2010, Differences in cardiac parameters among elite rowers and subelite rowers, Med Sci Sports Exerc, 42, 1215, 10.1249/MSS.0b013e3181c81604 Morganroth, 1975, Comparative left ventricular dimensions in trained athletes, Ann Intern Med, 82, 521, 10.7326/0003-4819-82-4-521 Fisman, 2002, Effect of intensive resistance training on isotonic exercise Doppler indexes of left ventricular systolic function, Am J Cardiol, 89, 887, 10.1016/S0002-9149(02)02210-5 Roy, 1988, Endurance vs. strength training: comparison of cardiac structures using normal predicted values, J Appl Physiol, 64, 2552, 10.1152/jappl.1988.64.6.2552 Pluim, 2000, The athlete's heart. A meta-analysis of cardiac structure and function, Circulation, 101, 336, 10.1161/01.CIR.101.3.336 Baggish, 2008, Training-specific changes in cardiac structure and function: a prospective and longitudinal assessment of competitive athletes, J Appl Physiol, 104, 1121, 10.1152/japplphysiol.01170.2007 Spence, 2011, A prospective randomised longitudinal MRI study of left ventricular adaptation to endurance and resistance exercise training in humans, J Physiol, 589, 5443, 10.1113/jphysiol.2011.217125 Fagard, 1984, Cardiac structure and function in cyclists and runners. Comparative echocardiographic study, Br Heart J, 52, 124, 10.1136/hrt.52.2.124 Bar-Shlomo, 1982, Left ventricular function in trained and untrained healthy subjects, Circulation, 65, 484, 10.1161/01.CIR.65.3.484 Bekaert, 1981, Non-invasive evaluation of cardiac function in professional cyclists, Br Heart J, 45, 213, 10.1136/hrt.45.2.213 Douglas, 1986, Left ventricular structure and function by echocardiography in ultraendurance athletes, Am J Cardiol, 58, 805, 10.1016/0002-9149(86)90358-9 Gilbert, 1977, Echocardiographic study of cardiac dimensions and function in the endurance-trained athlete, Am J Cardiol, 40, 528, 10.1016/0002-9149(77)90067-4 Abergel, 2004, Serial left ventricular adaptations in world-class professional cyclists: implications for disease screening and follow-up, J Am Coll Cardiol, 44, 144, 10.1016/j.jacc.2004.02.057 Richand, 2007, An ultrasound speckle tracking (two-dimensional strain) analysis of myocardial deformation in professional soccer players compared with healthy subjects and hypertrophic cardiomyopathy, Am J Cardiol, 100, 128, 10.1016/j.amjcard.2007.02.063 Cardim, 2003, Doppler tissue imaging: regional myocardial function in hypertrophic cardiomyopathy and in athlete's heart, J Am Soc Echocardiogr, 16, 223, 10.1067/mje.2003.13 Baggish, 2008, The impact of endurance exercise training on left ventricular systolic mechanics, Am J Physiol, 295, H1109 Weiner, 2010, The impact of endurance exercise training on left ventricular torsion, JACC Cardiovasc Imaging, 3, 1001, 10.1016/j.jcmg.2010.08.003 Naylor, 2005, Reduced ventricular flow propagation velocity in elite athletes is augmented with the resumption of exercise training, J Physiol, 563, 957, 10.1113/jphysiol.2004.078360 Caso, 2000, Pulsed Doppler tissue imaging in endurance athletes: relation between left ventricular preload and myocardial regional diastolic function, Am J Cardiol, 85, 1131, 10.1016/S0002-9149(00)00709-8 Tumuklu, 2007, Alterations in left ventricular structure and diastolic function in professional football players: assessment by tissue Doppler imaging and left ventricular flow propagation velocity, Echocardiography, 24, 140, 10.1111/j.1540-8175.2007.00367.x Prasad, 2007, The effects of aging and physical activity on Doppler measures of diastolic function, Am J Cardiol, 99, 1629, 10.1016/j.amjcard.2007.01.050 D'Andrea, 2010, Left ventricular myocardial velocities and deformation indexes in top-level athletes, J Am Soc Echocardiogr, 23, 1281, 10.1016/j.echo.2010.09.020 Hauser, 1985, Symmetric cardiac enlargement in highly trained endurance athletes: a two-dimensional echocardiographic study, Am Heart J, 109, 1038, 10.1016/0002-8703(85)90247-9 Henriksen, 1996, Echocardiographic right and left ventricular measurements in male elite endurance athletes, Eur Heart J, 17, 1121, 10.1093/oxfordjournals.eurheartj.a015009 Scharhag, 2002, Athlete's heart: right and left ventricular mass and function in male endurance athletes and untrained individuals determined by magnetic resonance imaging, J Am Coll Cardiol, 40, 1856, 10.1016/S0735-1097(02)02478-6 D'Andrea, 2011, Range of right heart measurements in top-level athletes: the training impact, Int J Cardiol, 10.1016/j.ijcard.2011.06.058 Kim, 2011, Significance of electrocardiographic right bundle branch block in trained athletes, Am J Cardiol, 107, 1083, 10.1016/j.amjcard.2010.11.037 Scharf, 2010, Cardiac magnetic resonance assessment of left and right ventricular morphologic and functional adaptations in professional soccer players, Am Heart J, 159, 911, 10.1016/j.ahj.2010.02.027 Hoglund, 1986, Enlarged left atrial dimension in former endurance athletes: an echocardiographic study, Int J Sports Med, 7, 133, 10.1055/s-2008-1025750 Pelliccia, 2005, Prevalence and clinical significance of left atrial remodeling in competitive athletes, J Am Coll Cardiol, 46, 690, 10.1016/j.jacc.2005.04.052 D'Andrea, 2010, Left atrial volume index in highly trained athletes, Am Heart J, 159, 1155, 10.1016/j.ahj.2010.03.036 Hoogsteen, 2003, Left atrial and ventricular dimensions in highly trained cyclists, Int J Cardiovasc Imaging, 19, 211, 10.1023/A:1023684430671 Wilhelm, 2011, Atrial remodeling, autonomic tone, and lifetime training hours in nonelite athletes, Am J Cardiol, 108, 580, 10.1016/j.amjcard.2011.03.086 Pelliccia, 2006, The genetics of left ventricular remodeling in competitive athletes, J Cardiovasc Med (Hagerstown), 7, 267, 10.2459/01.JCM.0000219319.20128.aa Pelliccia, 1996, Athlete's heart in women. Echocardiographic characterization of highly trained elite female athletes, JAMA, 276, 211, 10.1001/jama.1996.03540030045030 George, 1995, Electrocardiographic and echocardiographic characteristics of female athletes, Med Sci Sports Exerc, 27, 1362, 10.1249/00005768-199510000-00003 Sun, 2007, The upper limit of physiological cardiac hypertrophy in elite male and female athletes in China, Eur J Appl Physiol, 101, 457, 10.1007/s00421-007-0517-5 Whyte, 2004, Left ventricular morphology and function in female athletes: a meta-analysis, Int J Sports Med, 25, 380, 10.1055/s-2004-817827 Haykowsky, 1998, Effects of combined endurance and strength training on left ventricular morphology in male and female rowers, Can J Cardiol, 14, 387 Rowland, 2010, Influence of sex on the “Athlete's Heart” in trained cyclists, J Sci Med Sport, 13, 475, 10.1016/j.jsams.2009.10.488 Basavarajaiah, 2008, Ethnic differences in left ventricular remodeling in highly-trained athletes relevance to differentiating physiologic left ventricular hypertrophy from hypertrophic cardiomyopathy, J Am Coll Cardiol, 51, 2256, 10.1016/j.jacc.2007.12.061 Rawlins, 2010, Ethnic differences in physiological cardiac adaptation to intense physical exercise in highly trained female athletes, Circulation, 121, 1078, 10.1161/CIRCULATIONAHA.109.917211 Montgomery, 1997, Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training, Circulation, 96, 741, 10.1161/01.CIR.96.3.741 Karjalainen, 1999, Angiotensinogen gene M235T polymorphism predicts left ventricular hypertrophy in endurance athletes, J Am Coll Cardiol, 34, 494, 10.1016/S0735-1097(99)00199-0 Baggish, 2009, Impact of family hypertension history on exercise-induced cardiac remodeling, Am J Cardiol, 104, 101, 10.1016/j.amjcard.2009.02.052 Heineke, 2006, Regulation of cardiac hypertrophy by intracellular signalling pathways, Nat Rev Mol Cell Biol, 7, 589, 10.1038/nrm1983 Brancaccio, 2003, Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload, Nat Med, 9, 68, 10.1038/nm805 Heineke, 2005, Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc, Proc Natl Acad Sci U S A, 102, 1655, 10.1073/pnas.0405488102 Zou, 2004, Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II, Nat Cell Biol, 6, 499, 10.1038/ncb1137 Moritz, 1902, Uber orthodiagraphische Untersuchungen am Herzen, Med Wochenschr, 49 La Gerche, 2011, Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes, Eur Heart J, 10.1093/eurheartj/ehr397 Harper, 2009, Exercise-induced right ventricular dysplasia/cardiomyopathy–an emerging condition distinct from arrhythmogenic right ventricular dysplasia/cardiomyopathy, Heart Lung Circ, 18, 233, 10.1016/j.hlc.2008.01.005 Pelliccia, 2010, Long-term clinical consequences of intense, uninterrupted endurance training in olympic athletes, J Am Coll Cardiol, 55, 1619, 10.1016/j.jacc.2009.10.068 Sarna, 1993, Increased life expectancy of world class male athletes, Med Sci Sports Exerc, 25, 237, 10.1249/00005768-199302000-00013 Karvonen, 1974, Longevity of endurance skiers, Med Sci Sports, 6, 49 Taioli, 2007, All causes of mortality in male professional soccer players, Eur J Public Health, 17, 600, 10.1093/eurpub/ckm035 Waterbor, 1988, The mortality experience of major-league baseball players, N Engl J Med, 318, 1278, 10.1056/NEJM198805123181917 Blair, 1989, Physical fitness and all-cause mortality. A prospective study of healthy men and women, JAMA, 262, 2395, 10.1001/jama.1989.03430170057028 Williams, 2001, Physical fitness and activity as separate heart disease risk factors: a meta-analysis, Med Sci Sports Exerc, 33, 754, 10.1097/00005768-200105000-00012