Craik, 2013, The future of peptide-based drugs, Chem. Biol. Drug Des., 81, 136, 10.1111/cbdd.12055
Vrignaud, 2011, Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles, Biomaterials, 32, 8593, 10.1016/j.biomaterials.2011.07.057
Xu, 2012, A quality by design (QbD) case study on liposomes containing hydrophilic API:II. Screening of critical variables, and establishment of design space at laboratory scale, Int. J. Pharm., 423, 543, 10.1016/j.ijpharm.2011.11.036
Patel, 2011, Colloidal delivery systems in foods: a general comparison with oral drug delivery, LWT-Food Sci. Technol., 44, 1958, 10.1016/j.lwt.2011.04.005
Matsumura, 1986, A new concept for macromolecular therapeutics in cancer chemotherapy; mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS, Cancer Res., 46, 6387
Klibanov, 1990, Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes, FEBS Lett., 268, 235, 10.1016/0014-5793(90)81016-H
Allen, 1991, Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo, Biochim. Biophys. Acta, 1066, 29, 10.1016/0005-2736(91)90246-5
Torchilin, 2005, Recent advances with liposomes as pharmaceutical carriers, Nat. Rev. Drug Discov., 2, 145, 10.1038/nrd1632
Yamamoto, 2007, What are determining factors for stable drug incorporation into polymeric micelle carriers? Consideration on physical and chemical characters of the micelle inner core, J. Control. Release, 123, 11, 10.1016/j.jconrel.2007.07.008
Xu, 2012, Predicting hydrophilic drug encapsulation inside unilamellar liposomes, Int. J. Pharm., 423, 410, 10.1016/j.ijpharm.2011.12.019
Cortesi, 1999, Preparation of liposomes by reverse-phase evaporation using alternative organic solvents, J. Microencapsul., 16, 251, 10.1080/026520499289220
Mayer, 1985, Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles, Biochim. Biophys. Acta, 817, 193, 10.1016/0005-2736(85)90084-7
Haran, 1993, Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases, Biochim. Biophys. Acta, 1151, 201, 10.1016/0005-2736(93)90105-9
Barenholz, 2012, Doxil® — the first FDA-approved nano-drug: lessons learned, J. Control. Release, 160, 117, 10.1016/j.jconrel.2012.03.020
Bibi, 2012, Trigger release liposome systems: local and remote controlled delivery?, J. Microencapsul., 29, 262, 10.3109/02652048.2011.646330
Allen, 2013, Liposomal drug delivery systems: from concept to clinical applications, Adv. Drug Deliv. Rev., 65, 36, 10.1016/j.addr.2012.09.037
Kepczynski, 2008, Which physical and structural factors of liposome carriers control their drug-loading efficiency?, Chem. Phys. Lipids, 155, 7, 10.1016/j.chemphyslip.2008.05.174
Taylor, 1990, Drug entrapment and release from multilamellar and reverse-phase evaporation liposomes, Int. J. Pharm., 58, 49, 10.1016/0378-5173(90)90286-D
Manojlovic, 2008, Membrane interactions of ternary phospholipid/cholesterol bilayers and encapsulation efficiencies of a RIP II protein, Colloids Surf. B: Biointerfaces, 64, 284, 10.1016/j.colsurfb.2008.02.001
Glavas-Dodov, 2005, The effects of lyophilization on the stability of liposomes containing 5-FU, Int. J. Pharm., 291, 79, 10.1016/j.ijpharm.2004.07.045
Di Giulio, 1991, Encapsulation of ampicillin in reverse-phase evaporation liposomes: a direct evaluation by derivative spectrophotometry, Int. J. Pharm., 74, 183, 10.1016/0378-5173(91)90235-G
Zamboni, 2004, Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma, Cancer Chemother. Pharmacol., 53, 329, 10.1007/s00280-003-0719-4
Chaudhury, 2012, Lyophilization of cholesterol-free PEGylated liposomes and its impact on drug loading by passive equilibration, Int. J. Pharm., 430, 167, 10.1016/j.ijpharm.2012.04.036
Gürsoy, 2004, Co-encapsulation of isoniazid and rifampicin in liposomes and characterization of liposomes by derivative spectroscopy, Int. J. Pharm., 271, 115, 10.1016/j.ijpharm.2003.10.033
Han, 2012, Improved oral bioavailability of alendronate via the mucoadhesive liposomal delivery system, Eur. J. Pharm. Sci., 46, 500, 10.1016/j.ejps.2012.04.002
Moghaddam, 2011, The application of monolayer studies in the understanding of liposomal formulations, Int. J. Pharm., 417, 235, 10.1016/j.ijpharm.2011.01.020
Schneider, 1995, Generation of contrast-carrying liposomes of defined size with a new continuous high pressure extrusion method, Int. J. Pharm., 117, 1, 10.1016/0378-5173(94)00245-Z
Belletti, 2011, Novel polymeric/lipidic hybrid systems (PLHs) for effective Cidofovir delivery: preparation, characterization and comparative in vitro study with polymeric particles and liposomes, Int. J. Pharm., 413, 220, 10.1016/j.ijpharm.2011.04.025
Wang, 2013, Preparation and evaluation of lidocaine hydrochloride-loaded TAT-conjugated polymeric liposomes for transdermal delivery, Int. J. Pharm., 441, 748, 10.1016/j.ijpharm.2012.10.019
Villasmil-Sánchez, 2013, Thermal and 31P-NMR studies to elucidate sumatriptan succinate entrapment behavior in phosphatidylcholine/cholesterol liposomes. comparative 31P-NMR analysis on negatively and positively-charged liposomes, Colloids Surf. B: Biointerfaces, 105, 14, 10.1016/j.colsurfb.2012.12.019
Kajiwara, 2007, Long-circulating liposome encapsulated ganciclovir enhances the efficacy of HSV-TK suicide gene therapy, J. Control. Release, 120, 104, 10.1016/j.jconrel.2007.04.011
Ruozi, 2010, Cidofovir-loaded liposomes: an intro-study using BCBL-1 cell line as a model for primary effusion lymphoma, Eur. J. Pharm. Sci., 41, 254, 10.1016/j.ejps.2010.06.012
Bangham, 1965, Diffusion of univalent ions across the lamellae of swollen phospholipids, J. Mol. Biol., 13, 238, 10.1016/S0022-2836(65)80093-6
Szoka, 1978, Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation, Proc. Natl. Acad. Sci. U.S.A., 75, 4194, 10.1073/pnas.75.9.4194
Zadi, 2000, A novel method for high-yield entrapment of solutes into small liposomes, J. Liposome Res., 10, 73, 10.3109/08982100009031096
Castile, 1999, Factors affecting the size distribution of liposomes produced by freeze–thaw extrusion, Int. J. Pharm., 188, 87, 10.1016/S0378-5173(99)00207-0
Chapman, 1990, Factors affecting solute entrapment in POPC vesicles prepared by the freeze–thaw extrusion method, Chem. Phys. Lipids, 55, 73, 10.1016/0009-3084(90)90068-3
Anzai, 1990, Change in intravesicular volume of liposomes by freeze–thaw treatment as studied, Biochim. Biophys. Acta, 1021, 21, 10.1016/0005-2736(90)90378-2
Ueno, 2005, Effect of PEG lipid on fusion and fission of phospholipid vesicles in the process of freeze-thawing, Polymer, 46, 1257, 10.1016/j.polymer.2004.11.050
Hope, 1985, Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential, Biochim. Biophys. Acta, 812, 55, 10.1016/0005-2736(85)90521-8
Agashe, 2010, Improved formulation of liposome-encapsulated hemoglobin with an anionic non-phospholipid, Colloids Surf. B: Biointerfaces, 75, 573, 10.1016/j.colsurfb.2009.09.038
Akbarzadeh, 2013, Lipossome: classification, preparation and applications, Nanoscale Res. Lett., 8, 1, 10.1186/1556-276X-8-102
Vemuri, 1995, Preparation and characterization of liposomes as therapeutic delivery systems: a review, Pharm. Acta Helv., 70, 95, 10.1016/0031-6865(95)00010-7
Elorza, 1993, Characterization of 5-fluorouracil loaded liposomes prepared by reverse-phase evaporation or freezing-thawing extrusion methods: study of drug release, Biochim. Biophys. Acta, 1153, 135, 10.1016/0005-2736(93)90398-J
Zhang, 2012, The use of PEGylated liposomes to prolong the circulation lifetime of salvianolic acid B, Fitoterapia, 83, 678, 10.1016/j.fitote.2012.02.004
Muppidi, 2012, Development and stability studies of novel liposomal vancomycin formulations, ISRN Pharm., 2012, 1
Patil, 2014, Novel methods for liposome preparation, Chem. Phys. Lipids, 177, 8, 10.1016/j.chemphyslip.2013.10.011
Davies, 2012, Formation of liposomes using a 3D flow focusing microfluidic device with spatially patterned wettability by corona discharge, J. Micromech. Microeng., 22, 1, 10.1088/0960-1317/22/5/055003
Shum, 2008, Double emulsion templated monodisperse phospholipid vesicles, Langmuir, 24, 7651, 10.1021/la801833a
Deamer, 1972, The response of fluorescent amines to pH gradients across liposome membranes, Biochim. Biophys. Acta, 274, 323, 10.1016/0005-2736(72)90180-0
Nichols, 1976, Catecholamine uptake and concentration by liposomes maintaining pH gradients, Biochim. Biophys. Acta, 455, 269, 10.1016/0005-2736(76)90169-3
Ishida, 2002, Encapsulation of an antivasospastic drug, fasudil, into liposomes, and in vitro stability of the fasudil-loaded liposomes, Int. J. Pharm., 232, 59, 10.1016/S0378-5173(01)00896-1
Hwang, 1999, Remote loading of diclofenac, insulin and fluorescein isothiocyanate labeled insulin into liposomes by pH and acetate gradient methods, Int. J. Pharm., 179, 85, 10.1016/S0378-5173(98)00392-5
Clerc, 1998, A quantitative model for using acridine organge as a transmembrane pH gradient probe, Anal. Biochem., 259, 104, 10.1006/abio.1998.2639
Li, 1998, Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient, Biochim. Biophys. Acta, 1415, 23, 10.1016/S0005-2736(98)00175-8
Zucker, 2009, Liposome drugs’ loading efficiency: a working model based on loading conditions and drug's physicochemical properties, J. Control. Release, 139, 73, 10.1016/j.jconrel.2009.05.036
Clerc, 1995, Loading of amphipathic weak acids into liposomes in response to transmembrane calcium acetate gradients, Biochim. Biophys. Acta, 1240, 257, 10.1016/0005-2736(95)00214-6
Dos Santos, 2004, pH gradient loading of anthracyclines into cholesterol-free liposomes: enhancing drug loading rates through use of ethanol, Biochim. Biophys. Acta, 1661, 47, 10.1016/j.bbamem.2003.11.016
Fritze, 2006, Remote loading of doxorubicin into liposomes driven by a transmembrane phosphate gradient, Biochim. Biophys. Acta, 1758, 1633, 10.1016/j.bbamem.2006.05.028
Abrahama, 2004, An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes, J. Control. Release, 96, 449, 10.1016/j.jconrel.2004.02.017
Li, 2008, Copper ion-mediated liposomal encapsulation of mitoxantrone: the role of anions in drug loading, retention and release, Eur. J. Pharm. Sci., 34, 333, 10.1016/j.ejps.2008.05.006
Cui, 2009, Ni2+-mediated mitoxantrone encapsulation: Improved efficacy of fast release formulation, Int. J. Pharm., 368, 24, 10.1016/j.ijpharm.2008.09.045
Cern, 2012, Quantitative structure–property relationship modeling of remote liposome loading of drugs, J. Control. Release, 160, 147, 10.1016/j.jconrel.2011.11.029
Wong, 2003, Liposome delivery of ciprofloxacin against intracellular Francisella tularensis infection, J. Control. Release, 92, 265, 10.1016/S0168-3659(03)00358-4
Qiu, 2008, Preparation and in vitro evaluation of liposomal chloroquine diphosphate loaded by a transmembrane pH-gradient method, Int. J. Pharm., 361, 56, 10.1016/j.ijpharm.2008.05.010
Sun, 2012, Loading 3-deazaneplanocin A into pegylated unilamellar liposomes by forming transient phenylboronic acid–drug complex and its pharmacokinetic features in Sprague–Dawley rats, Eur. J. Pharm. Biopharm., 80, 323, 10.1016/j.ejpb.2011.10.014
Hwang, 2011, Fabrication of nano-scale liposomes containing doxorubicin using Shirasu porous glass membrane, Colloids Surf. A: Physicochem. Eng. Aspects, 392, 250, 10.1016/j.colsurfa.2011.09.063
Lee, 1995, Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro, Biochim. Biophys. Acta, 1233, 134, 10.1016/0005-2736(94)00235-H
Han, 2006, In vivo distribution and antitumor activity of heparin-stabilized doxorubicin-loaded liposomes, Int. J. Pharm., 313, 181, 10.1016/j.ijpharm.2006.02.007
Takeuchi, 1999, Prolonged circulation time of doxorubicin-loaded liposomes coated with a modified polyvinyl alcohol after intravenous injection in rats, Eur. J. Pharm. Biopharm., 48, 123, 10.1016/S0939-6411(99)00029-6
Stensrud, 2000, Formulation and characterisation of primaquine loaded liposomes prepared by a pH gradient using experimental design, Int. J. Pharm., 198, 213, 10.1016/S0378-5173(00)00338-0
Kizelsztein, 2009, Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis, J. Neuroimmunol., 213, 20, 10.1016/j.jneuroim.2009.05.019
Zucker, 2012, Characterization of PEGylated nanoliposomes co-remotely loaded with topotecan and vincristine: relating structure and pharmacokinetics to therapeutic efficacy, J. Control. Release, 160, 281, 10.1016/j.jconrel.2011.10.003
Tokudome, 1996, Antitumor activity of vincristine encapsulated in glucuronide-modified long-circulating liposomes in mice bearing Meth A sarcoma, Biochim. Biophys. Acta, 1279, 70, 10.1016/0005-2736(95)00242-1
Maeda, 2000, Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review, J. Control. Release, 65, 271, 10.1016/S0168-3659(99)00248-5
Maeda, 2003, Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications, Int. Immunopharmacol., 3, 319, 10.1016/S1567-5769(02)00271-0
Palmer, 1984, The mechanism of liposome accumulation in infarction, Biochim. Biophys. Acta, 797, 363, 10.1016/0304-4165(84)90258-7
Kelly, 2011, Targeted liposomal drug delivery to monocytes and macrophages, J. Drug Deliv., 2011, 1, 10.1155/2011/727241
Andresen, 2005, Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific drug release, Prog. Lipid Res., 44, 68, 10.1016/j.plipres.2004.12.001
Li, 2013, Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy, J. Control. Release, 168, 142, 10.1016/j.jconrel.2013.03.011
Wu, 2011, Epirubicin-encapsulated long-circulating thermosensitive liposome improves pharmacokinetics and antitumor therapeutic efficacy in animals, J. Liposome Res., 21, 221, 10.3109/08982104.2010.520273
Zhang, 2011, Development and characteristics of temperature-sensitive liposomes for vinorelbine bitartrate, Int. J. Pharm., 414, 56, 10.1016/j.ijpharm.2011.05.013
Ferreira, 2012, Technetium-99m-labeled ceftizoxime loaded long-circulating and pH-sensitive liposomes used to identify osteomyelitis, Bioorg. Med. Chem. Lett., 22, 4605, 10.1016/j.bmcl.2012.05.105
Morilla, 2005, Etanidazole in pH-sensitive liposomes: design, characterization and in vitro/in vivo anti-Trypanosoma cruzi activity, J. Control. Release, 103, 599, 10.1016/j.jconrel.2004.12.012
Torres, 2011, Improved paramagnetic liposomes for MRI visualization of pH triggered release, J. Control Release, 154, 196, 10.1016/j.jconrel.2011.05.017
Huang, 2004, Acoustically active liposomes for drug encapsulation and ultrasound-triggered release, Biochim. Biophys. Acta, 1665, 134, 10.1016/j.bbamem.2004.07.003
Huang, 2008, A method to co-encapsulate gas and drugs in liposomes for ultrasound-controlled drug delivery, Ultrasound. Med. Biol., 34, 1272, 10.1016/j.ultrasmedbio.2008.01.005
Kee, 2008, Synthesis, acoustic stability, and pharmacologic activities of papaverine-loaded echogenic liposomes for ultrasound controlled drug delivery, J. Liposome Res., 18, 263, 10.1080/08982100802354558
Babincová, 2002, AC-magnetic field controlled drug release from magnetoliposomes: design of a method for site-specific chemotherapy, Bioelectrochemistry, 55, 17, 10.1016/S1567-5394(01)00171-2
Nappini, 2010, Magnetoliposomes for controlled drug release in the presence of low-frequency magnetic field, Soft Matter, 6, 154, 10.1039/B915651H
Saiyed, 2010, Magnetic nanoformulation of azidothymidine 5′-triphosphate for targeted delivery across the blood–brain barrier, Int. J. Nanomed., 5, 157
Yavlovich, 2011, A novel class of photo-triggerable liposomes containing DPPC:DC8,9PC as vehicles for delivery of doxorubcin to cells, Biochim. Biophys. Acta, 1808, 117, 10.1016/j.bbamem.2010.07.030
Kulshrestha, 2012, In vitro application of paclitaxel loaded magnetoliposomes for combined chemotherapy and hyperthermia, Colloids Surf. B: Biointerfaces, 96, 1, 10.1016/j.colsurfb.2012.02.029
Yan, 2013, Paclitaxel-liposome–microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers, J. Control. Release, 166, 246, 10.1016/j.jconrel.2012.12.025
Kopechek, 2008, Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes, J. Ultrasound. Med., 27, 1597, 10.7863/jum.2008.27.11.1597
Drummond, 1999, Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors, Pharmacol. Rev., 51, 691
Durazo, 2011, Functionalized nanosystems for targeted mitochondrial delivery, Mithocondrion, 12, 190, 10.1016/j.mito.2011.11.001
Koren, 2012, Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity, J. Control. Release, 160, 264, 10.1016/j.jconrel.2011.12.002
Fang, 2011, The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect, Adv. Drug Deliv. Rev., 63, 136, 10.1016/j.addr.2010.04.009
Maeda, 1992, Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo, Bioconjug. Chem., 3, 351, 10.1021/bc00017a001
Jain, 1999, Transport of molecules, particles and cells in solid tumors, Annu. Rev. Biomed. Eng., 1, 241, 10.1146/annurev.bioeng.1.1.241
Jain, 2001, Delivery of molecular and cellular medicine to solid tumors, Adv. Drug Deliv. Rev., 46, 149, 10.1016/S0169-409X(00)00131-9
Tanaka, 2009, Nanotechnology for breast cancer therapy, Biomed. Microdev., 11, 49, 10.1007/s10544-008-9209-0
Maruyama, 2011, Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects, Adv. Drug Deliv. Rev., 63, 161, 10.1016/j.addr.2010.09.003
Stapleton, 2013, A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors, PLoS ONE, 8, 1, 10.1371/journal.pone.0081157
Li, 2008, Polymer-drug conjugates: recent development in clinical oncology, Adv. Drug Deliv. Rev., 60, 886, 10.1016/j.addr.2007.11.009
Petre, 2007, Liposomal daunorubicin as treatment for Kaposi's Sarcoma, Int. J. Nanomed., 2, 277
Nakamura, 2006, A polymeric micelle MRI contrast agent with changeable relaxivity, J. Control Release, 114, 325, 10.1016/j.jconrel.2006.05.030
Shiraishi, 2009, Preparation and in vivo imaging of PEG-poly(L-lysine)-based polymeric micelle MRI contrast agents, J. Control Release, 136, 14, 10.1016/j.jconrel.2009.01.010
Shiraishi, 2010, Polyion complex micelle MRI contrast agents from poly(ethylene glycol)-b-poly(l-lysine) block copolymers having Gd-DOTA; preparations and their control of T1-relaxivities and blood circulation characteristics, J. Control Release, 148, 160, 10.1016/j.jconrel.2010.08.018
Yokoyama, 2011, Clinical applications of polymeric micelle carrier systems in chemotherapy and image diagnosis of solid tumors, J. Exp. Clin. Med., 3, 151, 10.1016/j.jecm.2011.06.002
Folkman, 1992, Angiogenesis, J. Biol. Chem., 267, 10931, 10.1016/S0021-9258(19)49853-0
Holmgren, 1995, Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression, Nat. Med., 1, 149, 10.1038/nm0295-149
Alves-Rosa, 2000, Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model, Blood, 96, 2834, 10.1182/blood.V96.8.2834
Claassen, 1990, A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage ‘suicide’ technique, J. Immunol. Methods, 134, 153, 10.1016/0022-1759(90)90376-7
Van Rooijen, 1994, Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications, J. Immunol. Methods, 174, 83, 10.1016/0022-1759(94)90012-4
Jordan, 2003, Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model, Blood, 101, 594, 10.1182/blood-2001-11-0061
Summan, 2006, Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study, Am. J. Physiol. Regul. Integr. Comp. Physiol., 290, 1488, 10.1152/ajpregu.00465.2005
Moen, 2009, Liposomal amphotericin B: a review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections, Drugs, 69, 361, 10.2165/00003495-200969030-00010
Bakker-Woudenberg, 1986, Effect of liposome-entrapped ampicillin on survival of Listeria monocytogenes in murine peritoneal macrophages, Antimicrob. Agents Chemother., 30, 295, 10.1128/AAC.30.2.295
Majumdar, 1992, Efficacies of liposome-encapsulated streptomycin and ciprofloxacin against Mycobacterium avium-M. intracellulare complex infections in human peripheral blood monocyte/macrophages, Antimicrob. Agents Chemother., 36, 2808, 10.1128/AAC.36.12.2808
Kende, 1985, Enhanced efficacy of liposome-encapsulated ribavarin against Rift valley fever virus infection in mice, Antimicrob. Agents Chemother., 27, 903, 10.1128/AAC.27.6.903
Alving, 1978, Therapy of leishmaniasis: superior efficacies of liposome-encapsulated drugs, Proc. Natl. Acad. Sci. U.S.A., 75, 2959, 10.1073/pnas.75.6.2959
Koning, 2002, Interference of macrophages with immunotargeting of liposomes, J. Liposome Res., 12, 107, 10.1081/LPR-120004782
Harding, 1997, Immunogenicity and pharmacokinetic attributes of poly(ethylene glycol)-grafted immunoliposomes, Biochim. Biophys. Acta, 1327, 181, 10.1016/S0005-2736(97)00056-4
Barenholz, 2001, Liposome application: problems and prospects, Curr. Opin. Colloid Interface Sci., 6, 66, 10.1016/S1359-0294(00)00090-X
Goren, 2000, Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump, Clin. Cancer Res., 6, 1949
Biswas, 2013, Surface functionalization of doxorubicin-loaded liposomes with octa-arginine for enhanced anticancer activity, Eur. J. Pharm. Biopharm., 84, 517, 10.1016/j.ejpb.2012.12.021
Nagahara, 1998, Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration, Nat. Med., 4, 1449, 10.1038/4042
Vives, 1997, A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus, J. Biol. Chem., 272, 16010, 10.1074/jbc.272.25.16010
Chen, 2012, Targeting B lymphoma with nanoparticles bearing glycan ligands of CD22, Leuk. Lymphoma, 53, 208, 10.3109/10428194.2011.604755
Peer, 2004, Loading Mitomycin C inside long circulating hyaluronan targeted nano-liposomes increases its antitumor activity in three mice tumor models, Int. J. Cancer, 108, 780, 10.1002/ijc.11615
Yan, 2012, LyP-1-conjugated PEGylated liposomes: a carrier system for targeted therapy of lymphatic metastatic tumor, J. Control. Release, 157, 118, 10.1016/j.jconrel.2011.07.034
Pan, 2003, Antitumor activity of folate receptor-targeted liposomal doxorubicin in a KB oral carcinoma murine xenograft model, Pharm. Res., 20, 417, 10.1023/A:1022656105022
Watanabe, 2012, Functional coating of liposomes using a folate–polymer conjugate to target folate receptors, Int. J. Nanomed., 7, 3679
Xiang, 2008, Synthesis and evaluation of a novel ligand for folate-mediated targeting liposomes, Int. J. Pharm., 22, 29, 10.1016/j.ijpharm.2007.12.030
Nishikawa, 2012, Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer, J. Control. Release, 160, 274, 10.1016/j.jconrel.2011.10.010
Xiang, 2011, Chloride channel-mediated brain glioma targeting of chlorotoxin-modified doxorubicine-loaded liposomes, J. Control. Release, 152, 402, 10.1016/j.jconrel.2011.03.014
Wu, 2012, Methylene diphosphonate-conjugated adriamycin liposomes: preparation, characteristics, and targeted therapy for osteosarcomas in vitro and in vivo, Biomed. Microdev., 14, 497, 10.1007/s10544-011-9626-3
Hölig, 2004, Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells, Protein Eng. Des. Sel., 17, 433, 10.1093/protein/gzh055
Grange, 2010, Combined delivery and magnetic resonance imaging of neural cell adhesion molecule-targeted doxorubicin-containing liposomes in experimentally induced Kaposi's sarcoma, Cancer Res., 70, 2180, 10.1158/0008-5472.CAN-09-2821
Cai, 2014, Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy, Biomaterials, 35, 2283, 10.1016/j.biomaterials.2013.11.088
Paoli, 2014, Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes, J. Control. Release, 178, 108, 10.1016/j.jconrel.2014.01.005
Hatakeyama, 2007, Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes, Int. J. Pharm., 342, 194, 10.1016/j.ijpharm.2007.04.037
Park, 2014, Hyaluronic acid derivative-coated nanohybrid liposomes for cancer imaging and drug delivery, J. Control. Release, 174, 98, 10.1016/j.jconrel.2013.11.016
Pan, 2005, In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model, Anticancer Res., 25, 343
Ying, 2010, Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals, J. Control. Release, 141, 183, 10.1016/j.jconrel.2009.09.020
Chono, 2008, Efficient drug targeting to at alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections, J. Control. Release, 127, 50, 10.1016/j.jconrel.2007.12.011
Koning, 2006, Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis, Arthritis Rheum., 54, 1198, 10.1002/art.21719
Garg, 2009, Targeting colon cancer cells using PEGylated liposomes modified with a fibronectin-mimetic peptide, Int. J. Pharm., 366, 201, 10.1016/j.ijpharm.2008.09.016
Harata, 2013, CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome-positive acute lymphoblastic leukemia cells, Blood, 104, 1442, 10.1182/blood-2004-02-0588
Drummond, 2000, Current status of pH-sensitive liposomes in drug delivery, Prog. Lipid Res., 39, 409, 10.1016/S0163-7827(00)00011-4
Deshpande, 2013, Current trends in the use of liposomes for tumor targeting, Nanomedicine (Lond), 8, 10.2217/nnm.13.118
Perche, 2013, Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting, J. Drug Deliv., 2013, 1, 10.1155/2013/705265
Simard, 2009, pH-sensitive immunoliposomes specific to the CD33 cell surface antigen of leukemic cells, Int. J. Pharm., 381, 86, 10.1016/j.ijpharm.2009.05.013
Simões, 2001, On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes, Biochim. Biophys. Acta, 1515, 23, 10.1016/S0005-2736(01)00389-3
Ducat, 2011, Nuclear delivery of a therapeutic peptide by long circulating pH-sensitive liposomes: benefits over classical vesicles, Int. J. Pharm., 420, 319, 10.1016/j.ijpharm.2011.08.034
Litzinger, 1992, Phosphatidylethanolamine liposomes: drug delivery, gene transfer and immunodiagnostic applications, Biochim. Biophys. Acta, 1113, 201, 10.1016/0304-4157(92)90039-D
Obata, 2010, Evaluation of pH-responsive liposomes containing amino acid-based zwitterionic lipids for improving intracellular drug delivery in vitro and in vivo, J. Control. Release, 142, 267, 10.1016/j.jconrel.2009.10.023
A.M. Gomez, Fusogenic anti-PSMA liposomes for antivascular chemotherapy, 54f. Dissertation (Master), Graduate School New Brunswick Rutgers, The State University of New Jersey and The Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, New Brunswick, 2013, https://rucore.libraries.rutgers.edu/rutgers-lib/41774/PDF/1/.
Barros, 2011, Tumor bombesin analog loaded long-circulating and pH-sensitive liposomes as tool for tumor identification, Bioorg. Med. Chem. Lett., 21, 7373, 10.1016/j.bmcl.2011.10.016
Carmo, 2008, Biodistribution study and identification of inflammation sites using 99mTc-labelled stealth pH-sensitive liposomes, Nucl. Med. Commun., 29, 33, 10.1097/MNM.0b013e3282f1bc0d
Banerjee, 2012, Poly(styrene-co-maleic acid)-based pH-sensitive liposomes mediate cytosolic delivery of drugs for enhanced cancer chemotherapy, Int. J. Pharm., 436, 786, 10.1016/j.ijpharm.2012.07.059
Tannock, 1989, Acid pH in tumors and its potential for therpeutic exploitation, Cancer Res., 49, 4373
Van Sluis, 1999, In vivo imaging of extracellular pH using 1H MRSI, Magn. Reson. Med., 41, 743, 10.1002/(SICI)1522-2594(199904)41:4<743::AID-MRM13>3.0.CO;2-Z
Wijesinghe, 2013, pH dependent transfer of nano-pores into membrane of cancer cells to induce apoptosis, Sci. Rep., 3560, 1
Andreev, 2009, Targeting acidic diseased tissue: new technology based on use of the pH (Low) insertion peptide (pHLIP), Chim. Oggi, 27, 34
Reshetnyak, 2008, Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane, Proc. Natl. Acad. Sci. U.S.A., 105, 15340, 10.1073/pnas.0804746105
Andreev, 2007, Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo, Proc. Natl. Acad. Sci. U.S.A., 104, 7893, 10.1073/pnas.0702439104
Hunt, 1997, Spontaneous, pH-dependent membrane insertion of a transbilayer alpha-helix, Biochemistry, 36, 15177, 10.1021/bi970147b
Reshetnyak, 2007, A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers, Biophys. J., 93, 2363, 10.1529/biophysj.107.109967
Yao, 2013, pHLIP®-mediated delivery of PEGylated liposomes to cancer cells, J. Control. Release, 167, 228, 10.1016/j.jconrel.2013.01.037
Karve, 2010, The pH-dependent association with cancer cells of tunable functionalized lipid vesicles with encapsulated doxorubicin for high cell-kill selectivity, Biomaterials, 31, 4409, 10.1016/j.biomaterials.2010.01.064
Kim, 2009, Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice, J. Control. Release, 140, 55, 10.1016/j.jconrel.2009.07.005
Francis, 2001, In vitro evaluation of pHsensitive polymer/niosome complexes, Biomacromolecules, 2, 741, 10.1021/bm010036z
Meyer, 1998, Copolymers of N-isopropylacrylamide can trigger pH sensitivity to stable liposomes, FEBS Lett., 421, 61, 10.1016/S0014-5793(97)01520-2
Pétriat, 2004, Study of molecular interactions between a phospholipidic layer and a pH-sensitive polymer using the Langmuir balance technique, Langmuir, 20, 1393, 10.1021/la035583f
Zignani, 2000, In vitro characterization of a novel polymeric-based pH-sensitive liposome system, Biochim. Biophys. Acta, 1463, 383, 10.1016/S0005-2736(99)00234-5
Liu, 2014, Dynamic disordering of liposomal cocktails and the spatio-temporal favorable release of cargoes to circumvent drug resistance, Biomaterials, 35, 3406, 10.1016/j.biomaterials.2013.12.089
Soares, 2011, Liposomes radiolabeled with 159Gd: in vitro antitumoral activity, biodistribution study and scintigraphic image in Ehrlich tumor bearing mice, Eur. J. Pharm. Sci., 43, 290, 10.1016/j.ejps.2011.05.006
Soares, 2012, Antitumoral activity and toxicity of PEG-coated and PEG-folate-coated pH-sensitive liposomes containing 159Gd-DTPA-BMA in Ehrlich tumor bearing mice, Eur. J. Pharm. Sci., 45, 58, 10.1016/j.ejps.2011.10.018
Yatvin, 1978, Design of liposomes for enhanced local release of drugs by hyperthermia, Science, 202, 1290, 10.1126/science.364652
Weinstein, 1979, Liposomes and local hyperthermia: selective delivery of methotrexate to heated tumors, Science, 204, 188, 10.1126/science.432641
Kong, 2000, Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release, Cancer Res., 60, 6950
Needdham, 2000, A new temperature sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model, Cancer Res., 60, 1197
Ponce, 2007, Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects, J. Natl. Cancer Inst., 99, 53, 10.1093/jnci/djk005
Tagami, 2012, A thermosensitive liposome prepared with a Cu2+ gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy, J. Control. Release, 161, 142, 10.1016/j.jconrel.2012.03.023
Hildebrandt, 2002, The cellular and molecular basis of hyperthermia, Crit. Rev. Oncol. Hematol., 43, 33, 10.1016/S1040-8428(01)00179-2
Kong, 1999, Hyperthermia and liposomes, Int. J. Hyperthermia, 15, 345, 10.1080/026567399285558
Gong, 2001, Improving efficiency of adriamycin crossing blood brain barrier by combination of thermosensitive liposomes and hyperthermia, Biol. Pharm. Bull., 34, 1058, 10.1248/bpb.34.1058
Mills, 2005, Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition, Biochim. Biophys. Acta, 1716, 77, 10.1016/j.bbamem.2005.08.007
De Smet, 2010, Temperature-sensitive liposomes for doxorubicin delivery under MRI guidance, J. Control. Release, 143, 120, 10.1016/j.jconrel.2009.12.002
Li, 2014, A novel two-step mild hyperthermia for advanced liposomal chemotherapy, J. Control. Release, 174, 202, 10.1016/j.jconrel.2013.11.012
www.celsion.com.
Tagami, 2011, Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin, J. Control. Release, 152, 303, 10.1016/j.jconrel.2011.02.009
Tagami, 2011, MRI monitoring of intratumoral drug delivery and prediction of the therapeutic effect with a multifunctional thermosensitive liposome, Biomaterials, 32, 10.1016/j.biomaterials.2011.05.029
Kim, 2014, Temperature-triggered tumor-specific delivery of anticancer agentsby cRGD-conjugated thermosensitive liposomes, Colloids Surf. B: Biointerfaces, 116, 17, 10.1016/j.colsurfb.2013.12.045
Van Elk, 2014, Triggered release of doxorubicin from temperature-sensitive poly(N–(2-hydroxypropyl)-methacrylamide mono/dilactate) grafted liposomes, Biomacromolecules, 1002, 10.1021/bm401904u
Kono, 1999, Thermosensitive polymer-modified liposomes that release contents around physiological temperature, Biochim. Biophys Acta, 1416, 239, 10.1016/S0005-2736(98)00226-0
Kono, 2010, Highly temperature-sensitive liposomes based on a thermosensitive block copolymer for tumor-specific chemotherapy, Biomaterials, 31, 7096, 10.1016/j.biomaterials.2010.05.045
Kono, 2011, Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy, Biomaterials, 32, 1387, 10.1016/j.biomaterials.2010.10.050
Ta, 2010, Thermosensitive liposomes modified with poly (nisopropylacrylamide-co-propylacrylic acid) copolymers for triggered release of doxorubicin, Biomacromolecules, 11, 1915, 10.1021/bm1004993
Alkan-Onyuksel, 1996, Development of inherently echogenic liposomes as an ultrasonic contrast agent, J. Pharm. Sci., 85, 486, 10.1021/js950407f
Huang, 2001, Improving ultrasound reflectivity and stability of echogenic liposomal dispersions for use as targeted ultrasound contrast agents, J. Pharm. Sci., 90, 1917, 10.1002/jps.1142
Buchanan, 2010, Encapsulation of NF-κB decoy oligonucleotides within echogenic liposomes and ultrasound-triggered release, J. Control. Release, 141, 193, 10.1016/j.jconrel.2009.09.017
Newman, 2001, Ultrasound gene therapy: on the road from concept to reality, Echocardiography, 18, 339, 10.1046/j.1540-8175.2001.00339.x
Lin, 2014, Ultrasound sensitive eLiposomes containing doxorubicin for drug targeting therapy, Nanomedicine, 10, 67, 10.1016/j.nano.2013.06.011
Faria, 2013, Synthesis and characterization of magnetoliposomes for MRI contrast enhancement, Int. J. Pharm., 446, 183, 10.1016/j.ijpharm.2013.02.025
Frascione, 2012, Ultrasmall superparamagnetic iron oxide (USPIO)-based liposomes as magnetic resonance imaging probes, Int. J. Nanomed., 7, 2349
Soenen, 2011, MRI assessment of blood outgrowth endothelial cell homing using cationic magnetoliposomes, Biomaterials, 32, 4140, 10.1016/j.biomaterials.2011.02.037
Hamaguchi, 2003, Selective hyperthermia using magnetoliposomes to target cervical lymph node metastasis in a rabbit tongue tumor model, Cancer Sci., 94, 834, 10.1111/j.1349-7006.2003.tb01527.x
Kawai, 2005, Anticancer effect of hyperthermia on prostate cancer mediated by magnetite cationic liposomes and immune-response induction in transplanted syngeneic rats, Prostate, 64, 373, 10.1002/pros.20253
Fattahi, 2011, Magnetoliposomes as multimodal contrast agents for molecular imaging and cancer nanotheragnostics, Nanomedicine, 6, 529, 10.2217/nnm.11.14
Al-Jamal, 2007, Liposome – nanoparticle hybrids for multimodal diagnostic and therapeutic applications, Nanomedicine, 2, 85, 10.2217/17435889.2.1.85
Martina, 2005, Generation of superparamagnetic liposomes revealed as highly efficient MRI contrast agents for in vivo imaging, J. Am. Chem. Soc., 127, 10676, 10.1021/ja0516460
Soenen, 2009, Magnetoliposomes: versatile innovative nanocolloids for use in biothecnology and biomedicine, Nanomedicine, 4, 177, 10.2217/17435889.4.2.177
Soenen, 2009, Stable long-term intracellular labelling with fluorescently tagged cationic magnetoliposomes, Chembiochem, 10, 257, 10.1002/cbic.200800510
Rívièri, 2007, Magnetic targeting of nanometric magnetic fluid loaded liposomes to specific brain intravascular areas: a dynamic imaging study in mice, Radiology, 244, 439, 10.1148/radiol.2442060912
Clares, 2013, Nano-engineering of 5-fluorouracil-loaded magnetoliposomes for combined hyperthermia and chemotherapy against colon cancer, Eur. J. Pharm. Biopharm., 85, 329, 10.1016/j.ejpb.2013.01.028
Gonzales, 2005, Synthesis of magnetoliposomes with monodisperse iron oxide nanocrystal cores for hyperthermia, J. Magn. Magn. Mater., 293, 265, 10.1016/j.jmmm.2005.02.020
Tanaka, 2005, Heat immunotherapy using magnetic nanoparticles and dendritic cells for T-lymphoma, J. Biosci. Bioeng., 100, 112, 10.1263/jbb.100.112
Bonini, 2013, Nanostructures for magnetically triggered release of drugs and biomolecules, Curr. Opin. Colloid Interface Sci., 18, 459, 10.1016/j.cocis.2013.07.007
Qiu, 2013, Controllable release from magnetoliposomes by magnetic stimulation and thermal stimulation, Colloids Surf. B: Biointerfaces, 104, 326, 10.1016/j.colsurfb.2012.11.033
Tai, 2009, Thermosensitive liposomes entrapping iron oxide nanoparticles for controllable drug release, Nanotechnology, 20, 1, 10.1088/0957-4484/20/13/135101
Nahar, 2014, Starch-coated magnetic liposomes as an inhalable carrier for accumulation of fasudil in the pulmonary vasculature, Int. J. Pharm., 464, 185, 10.1016/j.ijpharm.2014.01.007
Bothun, 2011, Multicomponent folate-targeted magnetoliposomes: design, characterization, and cellular uptake, Nanomedicine, 7, 797, 10.1016/j.nano.2011.02.007
Jain, 2003, RGD-encored magnetic liposomes for monocytes/neutrophils-mediated brain targeting, Int. J. Pharm., 261, 43, 10.1016/S0378-5173(03)00269-2
Li, 2011, RGD-targeted paramagnetic liposomes for early detection of tumor: In vitro and in vivo studies, Eur. J. Radiol., 80, 598, 10.1016/j.ejrad.2011.01.051
Pradhan, 2010, Targeted temperature sensitive magnetic liposomes for thermo-chemotherapy, J. Control. Release, 142, 108, 10.1016/j.jconrel.2009.10.002
Menon, 2013, Nanomaterials for photo-based diagnostic and therapeutic applications, Theranostics, 3, 152, 10.7150/thno.5327
Zhu, 2013, Stimulus-responsive nanopreparations for tumor targeting, Integr. Biol. (Camb), 5, 1, 10.1039/C2IB20135F
de Visscher, 2011, Fluorescence localization and kinetics of mTHPC and liposomal formulations of mTHPC in the Window-Chamber Tumor Model, Lasers Surg. Med., 43, 528, 10.1002/lsm.21082
Yavlovich, 2010, Light-sensitive lipid-based nanoparticles for drug delivery: design principles and future considerations for biological applications, Mol. Membr. Biol., 27, 364, 10.3109/09687688.2010.507788
Leung, 2012, Light-activated content release from liposomes, Theranostics, 2, 1020, 10.7150/thno.4847
Wu, 2011, A gold nanoshell with a silica inner shell synthesized using liposome templates for doxorubicin loading and near-infrared photothermal therapy, Int. J. Nanomed., 6, 807
You, 2014, Near-infrared light-sensitive liposomes for the enhanced photothermal tumor treatment by the combination with chemotherapy, Pharm. Res., 31, 554, 10.1007/s11095-013-1180-7
Fan, 2013, Development of liposomal formulations: from concept to clinical investigations, Asian J. Pharm. Sci., 8, 81, 10.1016/j.ajps.2013.07.010
Chang, 2012, Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy, Int. J. Nanomed., 7, 49
Gabizon, 1994, Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes, Cancer Res., 54, 987
Silverman, 2013, Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine, Cancer Chemother. Pharmacol., 71, 555, 10.1007/s00280-012-2042-4
Drummond, 2006, Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy, Cancer Res., 66, 3271, 10.1158/0008-5472.CAN-05-4007
http://clinicaltrials.gov/ct2/show/study/NCT00734682?term=CPT-11+liposomes&rank=8.
http://www.clinicaltrials.gov/ct2/show/study/NCT00364143?term=irinotecan+liposomes&rank=1.
http://www.clinicaltrials.gov/ct2/show/NCT00765973?term.
http://www.exparel.com/pdf/Exparel_Monograph.pdf.
Immordino, 2006, Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential, Int. J. Nanomed., 1, 297
http://www.drugs.com/pro/depocyt.html.
http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bf2b4eaf-5227-42d9-af78 88d921e565f6.
http://www.drugcoverage.org/Myocet/pdf/736865117ACA44C0B454E5CBD9841D79_Product_Monograph_English_-_June_2006.pdf.
https://www.janssenmedicalinformation.com/assets/pdf/products/files/DOXIL/pi/OBI-ENCL-PI-000359.pdf.
Chuang, 2010, Endocytosis of PEGylated agents enhances cancer imaging and anticancer efficacy, Mol. Cancer Ther., 9, 1903, 10.1158/1535-7163.MCT-09-0899
http://www.drugs.com/pro/depodur.html.