Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Adhikary, 2005, Transcriptional regulation and transformation by Myc proteins, Nat. Rev. Mol. Cell Biol., 6, 635, 10.1038/nrm1703 Avilion, 2003, Multipotent cell lineages in early mouse development depend on SOX2 function, Genes Dev., 17, 126, 10.1101/gad.224503 Baudino, 2002, c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression, Genes Dev., 16, 2530, 10.1101/gad.1024602 Boyer, 2005, Core transcriptional regulatory circuitry in human embryonic stem cells, Cell, 122, 947, 10.1016/j.cell.2005.08.020 Bromberg, 1999, Stat3 as an oncogene, Cell, 98, 295, 10.1016/S0092-8674(00)81959-5 Burdon, 1999, Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells, Dev. Biol., 210, 30, 10.1006/dbio.1999.9265 Cartwright, 2005, LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism, Development, 132, 885, 10.1242/dev.01670 Cawley, 2004, Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs, Cell, 116, 499, 10.1016/S0092-8674(04)00127-8 Chambers, 2003, Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells, Cell, 113, 643, 10.1016/S0092-8674(03)00392-1 Chang, 2000, The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals, Mol. Cell. Biol., 20, 4309, 10.1128/MCB.20.12.4309-4319.2000 Cheng, 1998, Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation, Cell, 95, 793, 10.1016/S0092-8674(00)81702-X Cowan, 2005, Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells, Science, 309, 1369, 10.1126/science.1116447 Do, 2004, Nuclei of embryonic stem cells reprogram somatic cells, Stem Cells, 22, 941, 10.1634/stemcells.22-6-941 Domashenko, 1997, Expression of myc-family, myc-interacting, and myc-target genes during preimplantation mouse development, Mol. Reprod. Dev., 47, 57, 10.1002/(SICI)1098-2795(199705)47:1<57::AID-MRD8>3.0.CO;2-P Dyce, 2004, Stem cells with multilineage potential derived from porcine skin, Biochem. Biophys. Res. Commun., 316, 651, 10.1016/j.bbrc.2004.02.093 Evans, 1981, Establishment in culture of pluripotential cells from mouse embryos, Nature, 292, 154, 10.1038/292154a0 Fernandez, 2003, Genomic targets of the human c-Myc protein, Genes Dev., 17, 1115, 10.1101/gad.1067003 Katz, 2002, The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon, Development, 129, 2619, 10.1242/dev.129.11.2619 Kielman, 2002, Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling, Nat. Genet., 32, 594, 10.1038/ng1045 Li, 2005, Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4, Blood, 105, 635, 10.1182/blood-2004-07-2681 Lin, 2004, p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression, Nat. Cell Biol., 7, 165, 10.1038/ncb1211 Loh, 2006, The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells, Nat. Genet., 38, 431, 10.1038/ng1760 Martin, 1981, Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells, Proc. Natl. Acad. Sci. USA, 78, 7634, 10.1073/pnas.78.12.7634 Maruyama, 2005, Differential roles for sox15 and sox2 in transcriptional control in mouse embryonic stem cells, J. Biol. Chem., 280, 24371, 10.1074/jbc.M501423200 Matsuda, 1999, STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells, EMBO J., 18, 4261, 10.1093/emboj/18.15.4261 McMahon, 1998, The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins, Cell, 94, 363, 10.1016/S0092-8674(00)81479-8 Meiner, 1996, Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals, Proc. Natl. Acad. Sci. USA, 93, 14041, 10.1073/pnas.93.24.14041 Mitsui, 2003, The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells, Cell, 113, 631, 10.1016/S0092-8674(03)00393-3 Miyamoto, 2004, The adaptor protein Nck1 mediates endothelin A receptor-regulated cell migration through the Cdc42-dependent c-Jun N-terminal kinase pathway, J. Biol. Chem., 279, 34336, 10.1074/jbc.M402767200 Morita, 2000, Plat-E: an efficient and stable system for transient packaging of retroviruses, Gene Ther., 7, 1063, 10.1038/sj.gt.3301206 Nichols, 1998, Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4, Cell, 95, 379, 10.1016/S0092-8674(00)81769-9 Niwa, 1991, Efficient selection for high-expression transfectants with a novel eukaryotic vector, Gene, 108, 193, 10.1016/0378-1119(91)90434-D Niwa, 1998, Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3, Genes Dev., 12, 2048, 10.1101/gad.12.13.2048 Niwa, 2000, Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells, Nat. Genet., 24, 372, 10.1038/74199 Rowland, 2005, The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene, Nat. Cell Biol., 7, 1074, 10.1038/ncb1314 Sadot, 2002, Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells, J. Cell Sci., 115, 2771, 10.1242/jcs.115.13.2771 Sato, 2004, Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor, Nat. Med., 10, 55, 10.1038/nm979 Seoane, 2002, Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage, Nature, 419, 729, 10.1038/nature01119 Tada, 2001, Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells, Curr. Biol., 11, 1553, 10.1016/S0960-9822(01)00459-6 Takahashi, 2003, Role of ERas in promoting tumour-like properties in mouse embryonic stem cells, Nature, 423, 541, 10.1038/nature01646 Thomson, 1998, Embryonic stem cell lines derived from human blastocysts, Science, 282, 1145, 10.1126/science.282.5391.1145 Tokuzawa, 2003, Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development, Mol. Cell. Biol., 23, 2699, 10.1128/MCB.23.8.2699-2708.2003 Toma, 2001, Isolation of multipotent adult stem cells from the dermis of mammalian skin, Nat. Cell Biol., 3, 778, 10.1038/ncb0901-778 Toma, 2005, Isolation and characterization of multipotent skin-derived precursors from human skin, Stem Cells, 23, 727, 10.1634/stemcells.2004-0134 Vervoorts, 2003, Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP, EMBO Rep., 4, 484, 10.1038/sj.embor.embor821 Wilmut, 1997, Viable offspring derived from fetal and adult mammalian cells, Nature, 385, 810, 10.1038/385810a0 Yao, 2004, Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications, Mol. Ther., 10, 27, 10.1016/j.ymthe.2004.04.007 Yuan, 1995, Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3, Genes Dev., 9, 2635, 10.1101/gad.9.21.2635 Zhang, 2000, The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter, J. Biol. Chem., 275, 18391, 10.1074/jbc.C000062200 Zindy, 1998, Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization, Genes Dev., 12, 2424, 10.1101/gad.12.15.2424