Effects of gender and gonadectomy on responses to chronic benzodiazepine receptor agonist exposure in rats

Backstrom, 1976, Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle, Acta Neurol. Scand., 54, 321, 10.1111/j.1600-0404.1976.tb04363.x Browne, 1973, Benzodiazepines in the treatment of epilepsy. A review, Epilepsia, 14, 277, 10.1111/j.1528-1157.1973.tb03965.x Canonaco, 1989, Differential modulation of [3H]flunitrazepam binding in female rat brain by sex steroid hormones, Eur. J. Pharmacol., 170, 95, 10.1016/0014-2999(89)90140-4 Changeux, 1984, Acetylcholine receptor: An allosteric protein, Science, 225, 1335, 10.1126/science.6382611 Ellinwood, 1983, Effects of oral contraceptives on diazepam-induced psychomotor impairment, Clin. Pharmacol. Ther., 35, 360, 10.1038/clpt.1984.44 File, 1985, Tolerance to the behavioral actions of benzodiazepines, Neurosci. Biobehav. Rev., 9, 113, 10.1016/0149-7634(85)90037-5 Gallager, 1984, Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity, Nature, 308, 74, 10.1038/308074a0 Gallager, 1985, Continuous release of diazepam: Electrophysiological, biochemical and behavioral consequences, Brain Res., 342, 26, 10.1016/0006-8993(85)91349-6 Gallager, 1990, Chronic benzodiazepine agonist exposure and its consequences for GABA-benzodiazepine interactions, 91 Gee, 1988, Steroid modulation of the chloride ionophore in rat brain; structure-activity requirements, regional dependence and mechanism of action, J. Pharmacol. Exp. Ther., 246, 803 Gent, 1983, Development of tolerance to the anticonvulsant effects of clobazam, Eur. J. Pharmacol., 94, 155, 10.1016/0014-2999(83)90454-5 Goldberg, 1967, A comparative study of certain pharmacologic responses following acute and chronic administrations of chlordiazepoxide, Life Sci., 6, 481, 10.1016/0024-3205(67)90051-3 Greenblatt, 1978, Dependence, tolerance and addition to benzodiazepines: clinical and pharmacokinetic considerations, Drug Metab. Rev., 8, 13, 10.3109/03602537808993775 Greenblatt, 1980, Oxazepam kinetics: effects of age and sex, J. Pharmacol. Exp. Ther., 215, 86 Haefely, 1983, Neuropharmacology of benzodiazepines: synaptic mechanisms and neural basis of action, 21 Hamon, 1983, Biochemical and functional alterations of GABA receptors during chronic estradiol treatment, Brain Res., 279, 141, 10.1016/0006-8993(83)90172-5 Harrison, 1987, Structure-activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex, J. Pharmacol. Exp. Ther., 241, 346 Kendall, 1981, Imipramine: Effect of ovarian steroids on modifications in serotonin receptor binding, Science, 211, 1183, 10.1126/science.6258229 Lambert, 1989, Steroidal modulation of the GABAA-benzodiazepine receptor complex: an electrophysiological investigation, 139 Lowry, 1951, Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193, 265, 10.1016/S0021-9258(19)52451-6 Maggi, 1985, Role of female gonadal hormones in the CNS: Clinical and experimental aspects, Life Sci., 37, 893, 10.1016/0024-3205(85)90525-9 Majewska, 1986, Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor, Science, 232, 1004, 10.1126/science.2422758 Majewska, 1989, Pregnancy-induced alteration of GABAA receptor sensitivity in maternal brain; an antecedent of post-partum ‘blues’?, Brain Res., 482, 397, 10.1016/0006-8993(89)91208-0 McEwen, 1991, Non-genomic and genomic effects of steroids on neural activity, Trends Pharmacol. Sci., 12, 141, 10.1016/0165-6147(91)90531-V Miller, 1988, Chronic benzodiazepine administration I. Tolerance is associated with benzodiazepine receptor downregulation and decreased γ-aminobutyric acidA receptor function, J. Pharmacol. Exp. Ther., 246, 170 Morrow, 1990, Characterization of steroid interactions with γ-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites, Mol. Pharmacol., 37, 263 Newmark, 1980, Catamenial epilepsy: A review, Epilepsia, 21, 281, 10.1111/j.1528-1157.1980.tb04074.x Ochs, 1981, Diazepam kinetics in relation to age and sex, Pharmacology, 23, 24, 10.1159/000137524 Olsen, 1983, 3H-Bicuculline methochloride binding to low-affinity gamma-amino butyric acid receptor sites, J. Neurochem., 41, 1653, 10.1111/j.1471-4159.1983.tb00877.x O'Connor, 1988, Regional specificity of gamma-aminobutyric acid receptor regulation of estradiol, Neuroendocrinology, 47, 473, 10.1159/000124958 Pericic, 1985, Sex differences in the response of rats to drugs affecting GABAergic transmission, Life Sci., 36, 541, 10.1016/0024-3205(85)90635-6 Rosenberg, 1981, Tolerance during chronic benzodiazepine treatment associated with decreased receptor binding, Eur. J. Pharmacol., 70, 453, 10.1016/0014-2999(81)90356-3 Schiller, 1986, Enhancement of benzodiazepine binding by GABA is reduced rapidly during chronic exposure to flurazepam, Ann. N.Y. Acad. Sci., 463, 221, 10.1111/j.1749-6632.1986.tb21552.x Schumacher, 1989, Regulation of high-affinity GABAA receptors in specific brain regions by ovarian hormones, Neuroendocrinology, 50, 315, 10.1159/000125239 Selye, 1942, Correlations between the chemical structure and pharmacological actions of the steroids, Endocrinology, 30, 437, 10.1210/endo-30-3-437 Simmonds, 1987, Potentiators of responses to activation of γ-aminobutyric acid (GABAA receptors, Neuropharmacology, 26, 923, 10.1016/0028-3908(87)90071-2 Sher, 1983, Depression of benzodiazepine binding and diazepam potentiation of GABA-mediated inhibition after chronic exposure of spinal cord cultures to diazepam, Brain Res., 268, 171, 10.1016/0006-8993(83)90404-3 Smith, 1987, Sex steroid effects on extrahypothalamic CNS. II. Progesterone, alone and in combination with estrogen, modulates cerebellar responses to amino acid neurotransmitters, Brain Res., 422, 52, 10.1016/0006-8993(87)90539-7 Tietz, 1989, Regional GABA/benzodiazepine receptor/chloride channel coupling after acute and chronic benzodiazepine treatment, Eur. J. Pharmacol., 167, 57, 10.1016/0014-2999(89)90747-4 Waterhouse, 1984, Comparison of norepinephrine-and benzodizepine-induced augmentation of Purkinje cell responses to γ-aminobutyric acid (GABA), J. Pharmacol. Exp. Ther., 228, 257 Wilson, 1987, Effects of chronic diazepam exposure on GABA sensitivity and on benzodiazepine potentiation of GABA-mediated responses of substantia nigra pars reticulata neurons of rats, Eur. J. Pharmacol., 136, 333, 10.1016/0014-2999(87)90306-2 Wilson, 1986, Pharmacokinetics of imipramine are affected by age and sex in rats, Life Sci., 38, 711, 10.1016/0024-3205(86)90585-0 Woolley, 1962, The gonad-brain relationship: effects of female sex hormones on electroschock convulsions in the rat, Endocrinology, 70, 196, 10.1210/endo-70-2-196