The epidemiology of venous thromboembolism

Journal of Thrombosis and Thrombolysis - Tập 41 - Trang 3-14 - 2016
John A. Heit1, Frederick A. Spencer2, Richard H. White3
1Division of Cardiovascular Diseases (JAH), Mayo Clinic, Hematology Research-Stabile 660, Rochester, USA
2Division of Cardiology (FAS), McMaster University, Hamilton, USA
3Division of General Internal Medicine (RHW), University of California, Davis, Sacramento, USA

Tóm tắt

Venous thromboembolism (VTE) is categorized by the U.S. Surgeon General as a major public health problem. VTE is relatively common and associated with reduced survival and substantial health-care costs, and recurs frequently. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE risk factors, including increasing patient age and obesity, hospitalization for surgery or acute illness, nursing-home confinement, active cancer, trauma or fracture, immobility or leg paresis, superficial vein thrombosis, and, in women, pregnancy and puerperium, oral contraception, and hormone therapy. Although independent VTE risk factors and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence of VTE seems to be relatively constant, or even increasing.

Tài liệu tham khảo

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