Development and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation of diastereoisomers without use of a chiral column

Mohammad Alyamani1,2, Zhenfei Li1, Sunil K. Upadhyay3, David J. Anderson2, Richard J. Auchus3, Nima Sharifi1,4,5,2
1Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States
2Department of Chemistry, Cleveland State University, Cleveland, OH, United States
3Division of Endocrinology and Metabolism, Department of Internal Medicine and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, United States
4Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, United States
5Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, United States

Tài liệu tham khảo

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