Development and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation of diastereoisomers without use of a chiral column

The Journal of Steroid Biochemistry and Molecular Biology - Tập 172 - Trang 231-239 - 2017
Mohammad Alyamani1,2, Zhenfei Li1, Sunil K. Upadhyay3, David J. Anderson2, Richard J. Auchus3, Nima Sharifi1,4,5,2
1Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States
2Department of Chemistry, Cleveland State University, Cleveland, OH, United States
3Division of Endocrinology and Metabolism, Department of Internal Medicine and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, United States
4Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, United States
5Department of Hematology and Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, United States

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The Journal of Steroid Biochemistry and Molecular Biology

Tập 172

231-239

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