Schistosome infectivity in the snail, Biomphalaria glabrata, is partially dependent on the expression of Grctm6, a Guadeloupe Resistance Complex protein.

2012, Schistosomiasis: population requiring preventive chemotherapy and number of people treated in 2010, Wkly Epidemiol Rec, 87, 37

2016, Schistosomiasis: number of people treated worldwide in 2014, Wkly Epidemiol Rec, 91, 53

EJ Pearce, 2002, The immunobiology of schistosomiasis, Nat Rev Immunol, 2, 499, 10.1038/nri843

MC Martins, 2014, Usnic acid potassium salt: an alternative for the control of Biomphalaria glabrata (Say, 1818), PLoS One, 9, e111102, 10.1371/journal.pone.0111102

WR Jobin, 1970, Control of schistosomiasis in Guayama and Arroyo, Puerto Rico, Bull World Health Organ, 42, 151

CT Guimaraes, 2001, Possible competitive displacement of planorbids by Melanoides tuberculata in Minas Gerais, Brazil, Mem Inst Oswaldo Cruz, 96

MA Prentice, 1983, Displacement of Biomphalaria glabrata by the snail Thiara granifera in field habitats in St. Lucia, West Indies, Ann Trop Med Parasitol, 77, 51, 10.1080/00034983.1983.11811672

JP Pointier, 2001, Invading freshwater snails and biological control in Martinique Island, French West Indies, Mem Inst Oswaldo Cruz, 96, 67, 10.1590/S0074-02762001000900009

JP Pointier, 2000, Biological control of the snail hosts of schistosomiasis in areas of low transmission: the example of the Caribbean area, Acta Trop, 77, 53, 10.1016/S0001-706X(00)00123-6

JF Nguma, 1982, Elimination of Biomphalaria pfeifferi, Bulinus tropicus and Lymnaea natalensis by the ampullarid snail, Marisa cornuarietis, in a man-made dam in northern Tanzania, Acta Trop, 39, 85

SM Calumpang, 1995, Environmental impact of two molluscicides: niclosamide and metaldehyde in a rice paddy ecosystem, Bull Environ Contam Toxicol, 55, 494, 10.1007/BF00196027

SH Sokolow, 2016, Global Assessment of Schistosomiasis Control Over the Past Century Shows Targeting the Snail Intermediate Host Works Best, PLoS Negl Trop Dis, 10, e0004794, 10.1371/journal.pntd.0004794

JA Tennessen, 2015, Hyperdiverse gene cluster in snail host conveys resistance to human schistosome parasites, PLoS Genet, 11, e1005067, 10.1371/journal.pgen.1005067

PC Hanington, 2010, Role for a somatically diversified lectin in resistance of an invertebrate to parasite infection, Proc Natl Acad Sci U S A, 107, 21087, 10.1073/pnas.1011242107

EA Pila, 2016, Endogenous growth factor stimulation of hemocyte proliferation induces resistance to Schistosoma mansoni challenge in the snail host, Proc Natl Acad Sci U S A, 113, 5305, 10.1073/pnas.1521239113

JA Tennessen, 2015, Genome-Wide Scan and Test of Candidate Genes in the Snail Biomphalaria glabrata Reveal New Locus Influencing Resistance to Schistosoma mansoni, PLoS Negl Trop Dis, 9, e0004077, 10.1371/journal.pntd.0004077

CP Goodall, 2006, Biomphalaria glabrata cytosolic copper/zinc superoxide dismutase (SOD1) gene: association of SOD1 alleles with resistance/susceptibility to Schistosoma mansoni, Mol Biochem Parasitol, 147, 207, 10.1016/j.molbiopara.2006.02.009

A Theron, 2014, Multi-parasite host susceptibility and multi-host parasite infectivity: a new approach of the Biomphalaria glabrata/Schistosoma mansoni compatibility polymorphism, Infect Genet Evol, 26, 80, 10.1016/j.meegid.2014.04.025

PC Hanington, 2012, A somatically diversified defense factor, FREP3, is a determinant of snail resistance to schistosome infection, PLoS Negl Trop Dis, 6, e1591, 10.1371/journal.pntd.0001591

EA Pila, 2016, A Novel Toll-Like Receptor (TLR) Influences Compatibility between the Gastropod Biomphalaria glabrata, and the Digenean Trematode Schistosoma mansoni, PLoS Pathog, 12, e1005513, 10.1371/journal.ppat.1005513

ER Allan, 2012, Direct effects of triiodothyronine on production of anterior pituitary hormones and gonadal steroids in goldfish, Mol Reprod Dev, 79, 592, 10.1002/mrd.22066

ER Allan, 2014, NADPH oxidase modifies patterns of MHC class II-restricted epitopic repertoires through redox control of antigen processing, J Immunol, 192, 4989, 10.4049/jimmunol.1302896

ER Allan, 2015, Redundancy between Cysteine Cathepsins in Murine Experimental Autoimmune Encephalomyelitis, PLoS One, 10, e0128945, 10.1371/journal.pone.0128945

T Lehr, 2010, N-Glycosylation patterns of hemolymph glycoproteins from Biomphalaria glabrata strains expressing different susceptibility to Schistosoma mansoni infection, Exp Parasitol, 126, 592, 10.1016/j.exppara.2010.06.031

Y Jiang, 2006, In vivo and in vitro knockdown of FREP2 gene expression in the snail Biomphalaria glabrata using RNA interference, Dev Comp Immunol, 30, 855, 10.1016/j.dci.2005.12.004

M Mourao Mde, 2009, Role of the endogenous antioxidant system in the protection of Schistosoma mansoni primary sporocysts against exogenous oxidative stress, PLoS Negl Trop Dis, 3, e550, 10.1371/journal.pntd.0000550

M Knight, 2011, Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata, PLoS Negl Trop Dis, 5, e1212, 10.1371/journal.pntd.0001212

S Bais, 2015, Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni, PLoS Negl Trop Dis, 9, e0004295, 10.1371/journal.pntd.0004295

A Guidi, 2015, Application of RNAi to Genomic Drug Target Validation in Schistosomes, PLoS Negl Trop Dis, 9, e0003801, 10.1371/journal.pntd.0003801

J Hagen, 2014, Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo, Nat Commun, 5, 5375, 10.1038/ncomms6375

CL Valentim, 2013, Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites, Science, 342, 1385, 10.1126/science.1243106

R Bhardwaj, 2011, Using RNA interference in Schistosoma mansoni, Methods Mol Biol, 764, 223, 10.1007/978-1-61779-188-8_15

S Stefanic, 2010, RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening, PLoS Negl Trop Dis, 4, e850, 10.1371/journal.pntd.0000850

G Rinaldi, 2009, RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs, Mol Biochem Parasitol, 167, 118, 10.1016/j.molbiopara.2009.05.002

ME Morales, 2008, RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade, Mol Biochem Parasitol, 157, 160, 10.1016/j.molbiopara.2007.10.009

P Geldhof, 2007, RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects, Parasitology, 134, 609, 10.1017/S0031182006002071

KW Moremen, 2012, Vertebrate protein glycosylation: diversity, synthesis and function, Nat Rev Mol Cell Biol, 13, 448, 10.1038/nrm3383

K Futosi, 2013, Neutrophil cell surface receptors and their intracellular signal transduction pathways, Int Immunopharmacol, 17, 638, 10.1016/j.intimp.2013.06.034

W Le Clec'h, 2016, Characterization of hemolymph phenoloxidase activity in two Biomphalaria snail species and impact of Schistosoma mansoni infection, Parasit Vectors, 9, 32, 10.1186/s13071-016-1319-6

C Coustau, 2015, Advances in gastropod immunity from the study of the interaction between the snail Biomphalaria glabrata and its parasites: A review of research progress over the last decade, Fish Shellfish Immunol, 46, 5, 10.1016/j.fsi.2015.01.036

RC Bender, 2005, Respiratory burst of Biomphalaria glabrata hemocytes: Schistosoma mansoni-resistant snails produce more extracellular H2O2 than susceptible snails, J Parasitol, 91, 275, 10.1645/GE-415R

KJ Perry, 2015, CRISPR/Cas9-mediated genome modification in the mollusc, Crepidula fornicata, Genesis, 53, 237, 10.1002/dvg.22843

A Hammond, 2016, A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae, Nat Biotechnol, 34, 78, 10.1038/nbt.3439

S Reardon, 2016, Welcome to the CRISPR zoo, Nature, 531, 160, 10.1038/531160a

KM Esvelt, 2014, Concerning RNA-guided gene drives for the alteration of wild populations, Elife, e03401, 10.7554/eLife.03401