Hallmarks of cancer: Interactions with the tumor stroma
Tài liệu tham khảo
Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9
Kalluri, 2006, Fibroblasts in cancer, Nat. Rev. Cancer, 6, 392, 10.1038/nrc1877
Ostman, 2009, Cancer-associated fibroblasts and tumor growth–bystanders turning into key players, Curr. Opin. Genet. Dev., 19, 67, 10.1016/j.gde.2009.01.003
Sugimoto, 2006, Identification of fibroblast heterogeneity in the tumor microenvironment, Cancer Biol. Ther., 5, 1640, 10.4161/cbt.5.12.3354
Anderberg, 2009, Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts, Cancer Res., 69, 369, 10.1158/0008-5472.CAN-08-2724
Anderberg, 2009, On the origin of cancer-associated fibroblasts, Cell Cycle, 8, 1461, 10.4161/cc.8.10.8557
Karnoub, 2007, Mesenchymal stem cells within tumour stroma promote breast cancer metastasis, Nature, 449, 557, 10.1038/nature06188
Camps, 1990, Fibroblast-mediated acceleration of human epithelial tumor growth in vivo, Proc. Natl. Acad. Sci. USA, 87, 75, 10.1073/pnas.87.1.75
Morikawa, 2002, Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors, Am. J. Pathol., 160, 985, 10.1016/S0002-9440(10)64920-6
Gaengel, 2009, Endothelial-mural cell signaling in vascular development and angiogenesis, Arterioscler. Thromb. Vasc. Biol., 29, 630, 10.1161/ATVBAHA.107.161521
Abramsson, 2003, Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors, J. Clin. Invest., 112, 1142, 10.1172/JCI200318549
Song, 2005, PDGFRbeta+perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival, Nat. Cell Biol., 7, 870, 10.1038/ncb1288
Bhowmick, 2004, Stromal fibroblasts in cancer initiation and progression, Nature, 432, 332, 10.1038/nature03096
Demehri, 2009, Notch signaling in bulge stem cells is not required for selection of hair follicle fate, Development, 136, 891, 10.1242/dev.030700
Bhowmick, 2004, TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia, Science, 303, 848, 10.1126/science.1090922
Valin, 2009, PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts, PLoS ONE, 4, e4818, 10.1371/journal.pone.0004818
Kiaris, 2005, Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis, Cancer Res., 65, 1627, 10.1158/0008-5472.CAN-04-3791
Hill, 2005, Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis, Cell, 123, 1001, 10.1016/j.cell.2005.09.030
Trimboli, 2009, Pten in stromal fibroblasts suppresses mammary epithelial tumours, Nature, 461, 1084, 10.1038/nature08486
Strnad, 2010, Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes, Histochem. Cell Biol., 133, 201, 10.1007/s00418-009-0661-6
LeBedis, 2002, Peripheral lymph node stromal cells can promote growth and tumorigenicity of breast carcinoma cells through the release of IGF-I and EGF, Int. J. Cancer, 100, 2, 10.1002/ijc.10481
Levental, 2009, Matrix crosslinking forces tumor progression by enhancing integrin signaling, Cell, 139, 891, 10.1016/j.cell.2009.10.027
Thijssen, 2004, Angiogenesis gene expression profiling in xenograft models to study cellular interactions, Exp. Cell Res., 299, 286, 10.1016/j.yexcr.2004.06.014
Fukumura, 1998, Tumor induction of VEGF promoter activity in stromal cells, Cell, 94, 715, 10.1016/S0092-8674(00)81731-6
Amano, 2003, Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth, J. Exp. Med., 197, 221, 10.1084/jem.20021408
Williams, 2000, Host cyclooxygenase-2 modulates carcinoma growth, J. Clin. Invest., 105, 1589, 10.1172/JCI9621
Ikeda, 2004, Host stromal bradykinin B2 receptor signaling facilitates tumor-associated angiogenesis and tumor growth, Cancer Res., 64, 5178, 10.1158/0008-5472.CAN-03-3589
Pietras, 2008, Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting, PLoS Med., 5, e19, 10.1371/journal.pmed.0050019
Augsten, 2009, CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth, Proc. Natl. Acad. Sci. USA, 106, 3414, 10.1073/pnas.0813144106
Orimo, 2005, Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion, Cell, 121, 335, 10.1016/j.cell.2005.02.034
Furuhashi, 2004, Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate, Cancer Res., 64, 2725, 10.1158/0008-5472.CAN-03-1489
Robinson, 2008, The effects of tumor-derived platelet-derived growth factor on vascular morphology and function in vivo revealed by susceptibility MRI, Int. J. Cancer, 122, 1548, 10.1002/ijc.23279
McCarty, 2007, Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content, J. Clin. Invest., 117, 2114, 10.1172/JCI31334
Joyce, 2009, Microenvironmental regulation of metastasis, Nat. Rev. Cancer, 9, 239, 10.1038/nrc2618
Sung, 2008, Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis, Cancer Res., 68, 9996, 10.1158/0008-5472.CAN-08-2492
Xian, 2006, Pericytes limit tumor cell metastasis, J. Clin. Invest., 116, 642, 10.1172/JCI25705
Finak, 2008, Stromal gene expression predicts clinical outcome in breast cancer, Nat. Med., 14, 518, 10.1038/nm1764
Farmer, 2009, A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer, Nat. Med., 15, 68, 10.1038/nm.1908
Crawford, 2009, PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment, Cancer Cell, 15, 21, 10.1016/j.ccr.2008.12.004
Wang, 2009, Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors, Clin. Cancer Res., 15, 6630, 10.1158/1078-0432.CCR-09-1001
Pietras, 2001, Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors, Cancer Res., 61, 2929
Pietras, 2002, Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy, Cancer Res., 62, 5476
Olive, 2009, Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer, Science, 324, 1457, 10.1126/science.1171362
Yauch, 2008, A paracrine requirement for hedgehog signalling in cancer, Nature, 455, 406, 10.1038/nature07275
Santos, 2009, Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice, J. Clin. Invest., 119, 3613, 10.1172/JCI38988
Bergers, 2003, Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors, J. Clin. Invest., 111, 1287, 10.1172/JCI200317929
Erber, 2004, Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms, FASEB J., 18, 338, 10.1096/fj.03-0271fje
Pietras, 2005, A multitargeted, metronomic, and maximum-tolerated dose “chemo-switch” regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer, J. Clin. Oncol., 23, 939, 10.1200/JCO.2005.07.093
Tsujino, 2007, Stromal myofibroblasts predict disease recurrence for colorectal cancer, Clin. Cancer Res., 13, 2082, 10.1158/1078-0432.CCR-06-2191
Paulsson, 2009, Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer, Am. J. Pathol., 175, 334, 10.2353/ajpath.2009.081030
Infante, 2007, Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma, J. Clin. Oncol., 25, 319, 10.1200/JCO.2006.07.8824
Jarvius, 2007, In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method, Mol. Cell. Proteomics, 6, 1500, 10.1074/mcp.M700166-MCP200
R.A. Saito, P. Micke, P. Jönsson, J. Botling, K. Edlund, L. Johansson, P. Carlsson, K. Jirström, K. Miyazono, A. Östman. FoxF1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer, Cancer Res. (in press). doi:10.1158/0008-5472.CAN-09-3644.
Hasumi, 2007, Identification of a subset of pericytes that respond to combination therapy targeting PDGF and VEGF signaling, Int. J. Cancer, 121, 2606, 10.1002/ijc.22999
Bergers, 2008, Modes of resistance to anti-angiogenic therapy, Nat. Rev. Cancer, 8, 592, 10.1038/nrc2442
Crisan, 2008, A perivascular origin for mesenchymal stem cells in multiple human organs, Cell Stem Cell, 3, 301, 10.1016/j.stem.2008.07.003
Paquet-Fifield, 2009, A role for pericytes as microenvironmental regulators of human skin tissue regeneration, J. Clin. Invest., 119, 2795
Pietras, 2008, High levels of HIF-2alpha highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche, J. Pathol., 214, 482, 10.1002/path.2304
Calabrese, 2007, A perivascular niche for brain tumor stem cells, Cancer Cell, 11, 69, 10.1016/j.ccr.2006.11.020
Mantovani, 2008, Cancer-related inflammation, Nature, 454, 436, 10.1038/nature07205
Erez, 2010, Cancer Associated Fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-KB-dependent manner, Cancer Cell, 17, 135, 10.1016/j.ccr.2009.12.041
Boersma, 2008, A stromal gene signature associated with inflammatory breast cancer, Int. J. Cancer, 122, 1324, 10.1002/ijc.23237
Liao, 2009, Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model, PLoS ONE, 4, e7965, 10.1371/journal.pone.0007965
Balsamo, 2009, Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity, Proc. Natl. Acad. Sci. USA, 106, 20847, 10.1073/pnas.0906481106
Grum-Schwensen, 2010, Lung Metastasis Fails in MMTV-PyMT Oncomice Lacking S100A4 Due to a T-Cell Deficiency in Primary Tumors, Cancer Res., 70, 936, 10.1158/0008-5472.CAN-09-3220
Hamzah, 2008, Vascular normalization in Rgs5-deficient tumours promotes immune destruction, Nature, 453, 410, 10.1038/nature06868
Kaplan, 2005, VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche, Nature, 438, 820, 10.1038/nature04186
Erler, 2009, Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche, Cancer Cell, 15, 35, 10.1016/j.ccr.2008.11.012
McAllister, 2008, Systemic endocrine instigation of indolent tumor growth requires osteopontin, Cell, 133, 994, 10.1016/j.cell.2008.04.045
Wadlow, 2009, Systems-level modeling of cancer-fibroblast interaction, PLoS ONE, 4, e6888, 10.1371/journal.pone.0006888
Abe, 2008, Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2, Proc. Natl. Acad. Sci. USA, 105, 4838, 10.1073/pnas.0712216105
Ponten, 2008, The Human Protein Atlas–a tool for pathology, J. Pathol., 216, 387, 10.1002/path.2440