Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial

The Lancet - Tập 369 - Trang 208-216 - 2007
Jane Durga1,2, Martin PJ van Boxtel3, Evert G Schouten1, Frans J Kok1, Jelle Jolles3, Martijn B Katan2, Petra Verhoef1,2
1Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, Netherlands
2Wageningen Centre for Food Sciences, Wageningen, Netherlands
3Department of Psychiatry and Neuropsychology, Brain and Behaviour Institute, Maastricht University, Maastricht, Netherlands

Tài liệu tham khảo

van Boxtel, 1998, The relation between morbidity and cognitive performance in a normal aging population, J Gerontol A Biol Sci Med Sci, 53, M147, 10.1093/gerona/53A.2.M147 Lövdén, 2005, Studying individual aging in an international context: typical pathos of age-related, dementia-related, and mortality-related cognitive development in old age, Psych. Aging, 20, 303, 10.1037/0882-7974.20.2.303 Petersen, 1999, Mild cognitive impairment: clinical characterization and outcome, Arch Neurol, 56, 303, 10.1001/archneur.56.3.303 Fillit, 2002, Achieving and maintaining cognitive vitality with aging, Mayo Clin Proc, 77, 681, 10.4065/77.7.681 Calvaresi, 2001, B vitamins, cognition, and aging: a review, J Geronto. B Psychol Sci Soc Sci, 56, 327, 10.1093/geronb/56.6.P327 Mattson, 2003, Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders, Trends Neurosci, 26, 137, 10.1016/S0166-2236(03)00032-8 Morris, 2005, Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons, Arch Neurol, 62, 641, 10.1001/archneur.62.4.641 Malouf, 2003, Folic acid with or without vitamin B12 for cognition and dementia, Cochrane Database Sys Rev, 4, CD004514 Folstein, 1975, “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician, J Psychiatr Res, 12, 189, 10.1016/0022-3956(75)90026-6 Fioravanti, 1997, Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits, Arch Gerontol Geriatr, 26, 1, 10.1016/S0167-4943(97)00028-9 Sommer, 2003, Folic acid supplementation in dementia: a preliminary report, J Geriatr Psychiatry Neurol, 16, 156, 10.1177/0891988703256052 Eussen, 2006, Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial, Am J Clin Nutr, 84, 361, 10.1093/ajcn/84.2.361 McMahon, 2006, A controlled trial of homocysteine lowering and cognitive performance, N Engl J Med, 354, 2764, 10.1056/NEJMoa054025 Stott, 2005, Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease, Am J Clin Nutr, 82, 1320, 10.1093/ajcn/82.6.1320 Bryan, 2002, Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages, J Nutr, 132, 1345, 10.1093/jn/132.6.1345 Toole, 2004, Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial, JAMA, 291, 565, 10.1001/jama.291.5.565 Clarke, 2003, Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia, J Intern Med, 254, 67, 10.1046/j.1365-2796.2003.01154.x Lewerin, 2005, Significant correlations of plasma homocysteine and serum methylmalonic acid with movement and cognitive performance in elderly subjects but no improvement from short-term vitamin therapy: a placebo-controlled randomized study, Am J Clin Nutr, 81, 1155, 10.1093/ajcn/81.5.1155 Obied, 2005, Effect of the B-vitamins on cognitive function in elderly people with mild cognitive dysfunction [abstract], Clin Chem Lab Med, 43, A28 Refsum, 2004, Facts and recommendations about total homocysteine determinations: an expert opinion, Clin Chem, 50, 3, 10.1373/clinchem.2003.021634 Jolles Durga, 2006, Folate and the methylenetetrahydrofolate reductase 677C—>T mutation correlate with cognitive performance, Neurobiol Aging, 27, 334, 10.1016/j.neurobiolaging.2005.01.003 van der Elst, 2005, Rey's verbal learning test: normative data for 1855 healthy participants ages 24–81 years and the influence of age, sex, education, and mode of presentation, J Int Neuropsychol Soc, 11, 290, 10.1017/S1355617705050344 van der Elst, 2006, The Concept Shifting Test: adult noramtuive data, Psychol Assess, 18, 424, 10.1037/1040-3590.18.4.424 van der Elst, 2006, The Stroop Color-word Test: influence of age, sex, and education; and normative data for a large sample across the adult range, Assessment, 13, 62, 10.1177/1073191105283427 van der Elst, 2006, The Letter Digit Substitution Test: normative data for 1858 healthy participants aged 24–81 years from the Maastricht Aging Study: influence of age, education and sex, J Clin Exp Neuropsychol, 28, 998, 10.1080/13803390591004428 van der Elst, 2006, Normative data for the animal, profession and letter M naming verbal fluency tests for Dutch speaking participants and the effets of age, education, and sex, J Int Neuropsych Soc, 12, 80, 10.1017/S1355617706060115 Frosst, 1995, A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase, Nat Genet, 10, 111, 10.1038/ng0595-111 De Bie, 1987 Kalmijn, 2004, Dietary intake of fatty acids and fish in relation to cognitive performance at middle age, Neurology, 62, 275, 10.1212/01.WNL.0000103860.75218.A5 Scarmeas, 2006, Education and rates of cognitive decline in incident Alzheimer's disease, J Neurol Neurosurg Psychiatry, 77, 308, 10.1136/jnnp.2005.072306 Salthouse, 1996, The processing-speed theory of adult age differences in cognition, Psychol Rev, 103, 403, 10.1037/0033-295X.103.3.403 den Heijer, 2003, Homocysteine and brain atrophy on MRI of non-demented elderly, Brain, 126, 170, 10.1093/brain/awg006 Horn, 1967, Age differences in fluid and crystallized intelligence, Acta Psychol, 26, 107, 10.1016/0001-6918(67)90011-X Cooney, 1988, The relationship between prior functioning on cognitive and personality dimensions and subject attrition in longitudinal research, J Gerontol, 43, 12, 10.1093/geronj/43.1.P12 Kaplan, 2001, Dietary protein, carbohydrate, and fat enhance memory performance in the healthy elderly, Am J Clin Nutr, 74, 687, 10.1093/ajcn/74.5.687 Campbell, 1996, How safe are folic acid supplements?, Arch Intern Med, 156, 1638, 10.1001/archinte.1996.00440140058005 Brayne, 1988, Normal ageing, impaired cognitive function, and senile dementia of the Alzheimer's type: a continuum?, Lancet, 331, 1265, 10.1016/S0140-6736(88)92081-8 Morrison, 1997, Life and death of neurons in the aging brain, Science, 278, 412, 10.1126/science.278.5337.412 Visser, 2001, Diagnosis of preclinical Alzheimer's disease in a clinical setting, Int Psychogeriatr, 13, 411, 10.1017/S1041610201007839