Evaluation of Regional Variability and Measurement Reproducibility of Intravoxel Incoherent Motion Diffusion Weighted Imaging Using a Cardiac Stationary Phase Based ECG Trigger Method

BioMed Research International - Tập 2018 - Trang 1-11 - 2018
Zhiming Xiang1, Zhu Ai1, Jianke Liang1, Guijin Li2, Xiaolei Zhu2, Xu Yan3
1Department of Radiology, Guangzhou Panyu Center Hospital, Medical Imaging Institute of Panyu, 8 Fuyu Dong Road, Panyu District, Guangzhou 510080, China
2Siemens Healthcare, MR Scientific Marketing NE Asia, Guangzhou, China
3Siemens Healthcare, MR Collaboration NE Asia, Shanghai, China

Tóm tắt

Purpose. To evaluate the performance of an optimized ECG trigger diffusion weighted imaging (DWI) sequence in liver and its application in liver disease. Materials and Methods. Eighteen healthy volunteers underwent intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) scan of the liver twice in 1.5T MR scanner with signed informed consent approved by local ethic committees. A new method, called cardiac stationary phase based ECG trigger (CaspECG), and FB method were applied. The apparent diffusion coefficient (ADC) and the IVIM parameters, including pure diffusion coefficient (D), perfusion-related diffusion coefficient (D⁎), and perfusion fraction, (PF) were calculated, and then 18 region of interests were drawn on these parameter maps independently by two readers through whole hepatic lobe. The regional variability and reproducibility between two repeated scans were evaluated using interclass correlation coefficients (ICCs) and Bland-Altman plot, respectively, and compared between the CaspECG and FB methods. The signal-to-noise ratio (SNR) of DWI data was also evaluated. Result. Compared to the FB method, the proposed CaspECG method showed significant higher SNRs in DWI data, lower regional variability between left and right hepatic lobes, and higher reproducibility of ADC, PF, D, and D⁎ between repeat scans [left lobe, limit of agreement (LOA) of Bland-Altman plot: 10.1%, 18.3%, 19.8%, and 59.2%; right lobe, LOA: 10.25%, 14.15%, 16.45%, and 39.45%]. D⁎ showed the worst reproducibility in all parameters. Conclusion. The novel CaspECG method outperformed the FB method in compensating the cardiac motion induced artifacts in DWI data and generating more reliable quantitative parameters, with less regional variability and higher repeatability, especially in the left hepatic lobe.

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10.1016/j.ejrad.2011.02.019

10.1007/s00330-015-3835-8

10.1148/radiol.2241011117

10.1148/radiology.201.3.8939209

10.1148/radiology.168.2.3393671

10.1002/jmri.1880010103

10.1148/radiology.161.2.3763909

10.1148/radiology.177.2.2217777

2016, Abdom Radiol (NY), 15, 1

10.2147/OTT.S104770

10.1016/j.mri.2016.05.013

10.1148/radiol.2016142084

10.1148/radiol.2016151570

10.1148/radiol.2015141974

10.1148/radiol.15141350

10.1148/radiol.13131572

10.1002/jmri.23744

10.1097/RCT.0000000000000064

2012, Investigative Radiology, 47, 226, 10.1097/RLI.0b013e3182396410

10.1016/j.ijrobp.2006.11.057

10.1148/radiol.11101659

10.1148/rg.2015140234

10.1148/radiol.2462062166

1986, The Lancet, 1, 307

10.1007/s10334-013-0375-6

10.1148/radiol.14140759

10.1055/s-0042-119452

10.1148/radiol.2203010055

2009, Magma, 22, 319, 10.1007/s10334-009-0183-1

2006, Japanese Journal of Radiology, 24, 438

10.1007/s10334-012-0348-1

10.1148/radiol.10091706

10.1007/s00330-012-2604-1

10.1148/radiol.2493080080

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BioMed Research International

Tập 2018

1-11

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