6 Von Willebrand factor and platelet function

Aarts, 1983, Red blood cell size is important for adherence of blood platelets to artery subendothelium, Blood, 62, 214, 10.1182/blood.V62.1.214.214 Aarts, 1984, Red blood cell deformability influences platelets-vessel wall interaction in flowing blood, Blood, 64, 1228, 10.1182/blood.V64.6.1228.1228 Assouline, 1988, The human gene for von Willebrand factor: identification of repetitive Alu sequences 5′ to the transcription initiation site, Biochemical and Biophysical Research Communications, 153, 1159, 10.1016/S0006-291X(88)81349-4 Bahnak, 1988, Carrier detection in severe (Type III) von Willebrand disease using two intragenic restriction fragment length polymorphisms, Thrombosis and Haemostasis, 60, 178, 10.1055/s-0038-1647025 Bahnak, 1989, Expression of von Willebrand factor in porcine vessels: heterogeneity at the level of von Willebrand factor mRNA, Journal of Cellular Physiology, 138, 305, 10.1002/jcp.1041380212 Batlle, 1986, The heterogeneity of type IIA von Willebrand's disease: studies with protease inhibitors, Blood, 68, 1207, 10.1182/blood.V68.6.1207.1207 Batlle, 1986, Von Willebrand disease type IIC with different abnormalities of von Willebrand factor in the same sibship, American Journal of Hematology, 21, 177, 10.1002/ajh.2830210207 Batlle, 1986, Multimeric pattern discrepancy between platelet and plasma von Willebrand factor in type IIC von Willebrand disease, American Journal of Hematology, 22, 87, 10.1002/ajh.2830220113 Baumgartner, 1976, Adhesion and aggregation: morphologic demonstration, quantitation in vivo and in vitro, 23 Berkowitz, 1987, Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin, Journal of Clinical Investigation, 79, 524, 10.1172/JCI112843 Berliner, 1986, A relatively high frequency of severe (type III) von Willebrand's disease in Israel, British Journal of Haematology, 62, 535, 10.1111/j.1365-2141.1986.tb02966.x Bernardi, 1987, Two Taq 1 RFLPs in the human von Willebrand factor gene, Nucleic Acids Research, 15, 1347, 10.1093/nar/15.3.1347 Bernardi, 1988, Von Willebrand disease investigated by two novel RFLPs, British Journal of Haematology, 68, 243, 10.1111/j.1365-2141.1988.tb06196.x Bloom, 1987, Inherited disorders of blood coagulation, 393 Bockenstedt, 1986, Structural basis of von Willebrand factor binding to platelet glycoprotein Ib and collagen. Effects of disulfide reduction and limited proteolysis of polymeric von Willebrand factor, Journal of Clinical Investigation, 77, 743, 10.1172/JCI112369 Bolhuis, 1981, Binding of factor VIII-von Willebrand factor to human arterial subendothelium precedes increased platelet adhesion and enhances platelet spreading, Journal of Laboratory and Clinical Medicine, 97, 568 Bonthron, 1986, Structure of pre-pro-von Willebrand factor and its expression in heterologous cells, Nature, 324, 270, 10.1038/324270a0 Bonthron, 1988, The human von Willebrand factor gene: structure of the 5′ region, European Journal of Biochemistry, 171, 51, 10.1111/j.1432-1033.1988.tb13757.x Bosma, 1988, Human plasminogen activator inhibitor-1 gene, Journal of Biological Chemistry, 263, 9129, 10.1016/S0021-9258(19)76517-X Bowie, 1986, Transplantation of normal bone marrow into a pig with severe von Willebrand's disease, Journal of Clinical Investigation, 78, 26, 10.1172/JCI112560 Chopek, 1986, Human von Willebrand factor: a multivalent protein composed of identical subunits, Biochemistry, 25, 3146, 10.1021/bi00359a012 Ciavarella, 1985, High-resolution analysis of von Willebrand factor multimeric composition defines a new variant of type I von Willebrand disease with aberrant structure but presence of all size multimers (type IC), Blood, 66, 1423, 10.1182/blood.V66.6.1423.1423 Coller, 1983, Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor, Blood, 61, 99, 10.1182/blood.V61.1.99.99 Collins, 1987, Molecular cloning of the human gene for von Willebrand factor and identification of the transcription initiation site, 84, 4393 Collins, 1987, Identification of a functional promoter for the human von Willebrand factor gene, Blood, 70, 385a Cooper, 1987, Nucleotide sequence of the mouse α1-acid glycoprotein gene 1, Biochemistry, 26, 5244, 10.1021/bi00391a006 Counts, 1978, Disulfide bonds and the quaternary structure of factor VIII/von Willebrand factor, Journal of Clinical Investigation, 62, 702, 10.1172/JCI109178 Cramer, 1985, Excentric localization of von Willebrand factor in an internal structure of platelet α-granule resembling that of Weibel-Palade bodies, Blood, 66, 710, 10.1182/blood.V66.3.710.710 de Groot, 1984, Thrombin-induced release of von Willebrand factor from endothelial cells is mediated by phospholipid methylation, Journal of Biological Chemistry, 259, 13329, 10.1016/S0021-9258(18)90698-8 de Groot, 1987, Perturbation of human endothelial cells by thrombin or PMA changes the reactivity of their extracellular matrix towards platelets, Journal of Cell Biology, 104, 697, 10.1083/jcb.104.3.697 de Groot, 1987, Interleukin-1 inhibits the synthesis of von Willebrand factor in endothelial cells which results in a decreased reactivity of their matrix towards platelets, Arteriosclerosis, 7, 605, 10.1161/01.ATV.7.6.605 de Groot, 1988, Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagen, Journal of Clinical Investigation, 82, 65, 10.1172/JCI113602 de Marco, 1985, Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation, Journal of Clinical Investigation, 75, 1198, 10.1172/JCI111816 de Marco, 1986, Von Willebrand factor interaction with the glycoprotein IIb/IIIa complex. Its role in platelet function as demonstrated in patients with congenital afibrinogenemia, Journal of Clinical Investigation, 77, 1272, 10.1172/JCI112430 Donner, 1987, Type IIB von Willebrand's disease with probable autosomal recessive inheritance and presenting as thrombocytopenia in infancy, British Journal of Haematology, 66, 349, 10.1111/j.1365-2141.1987.tb06922.x Fass, 1978, Porcine Willebrand factor: a population of multimers, Journal of Laboratory and Clinical Medicine, 91, 307 Fauvel, 1983, Interaction of blood platelets with a microfibrillar extract from adult bovine aorta. Requirement for von Willebrand factor, 80, 551 Fay, 1986, Propolypeptide of von Willebrand factor circulates in blood and is identical to von Willebrand antigen II, Sciences, 232, 995, 10.1126/science.3486471 Federici, 1986, Heterogeneity in type IIB von Willebrand disease: two unrelated cases with no family history and mild abnormalities of ristocetin-induced interaction between von Willebrand factor and platelets, American Journal of Hematology, 23, 381, 10.1002/ajh.2830230410 Federici, 1988, Adhesive properties of the carbohydrate-modified von Willebrand factor (CHO-vWF), Blood, 71, 947, 10.1182/blood.V71.4.947.947 Foster, 1987, A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor, Journal of Biological Chemistry, 262, 8443, 10.1016/S0021-9258(18)47430-3 Fowler, 1985, Substructure of human von Willebrand factor, Journal of Clinical Investigation, 76, 1491, 10.1172/JCI112129 Fressinaud, 1987, Platelet von Willebrand factor: evidence for its involvement in platelet adhesion to collagen, Blood, 70, 1214, 10.1182/blood.V70.4.1214.1214 Fressinaud, 1988, Von Willebrand factor-mediated platelet adhesion to collagen involves platelet membrane glycoprotein IIb/IIIa as well as glycoprotein Ib, Journal of Laboratory and Clinical Medicine, 112, 58 Fressinaud, 1988, Synthetic RGDS-containing peptides of von Willebrand factor inhibit platelet adhesion to collagen, Thrombosis and Haemostasis Fretto, 1986, Substructure of human von Willebrand factor: proteolysis by V8 and characterization of two functional domains, Journal of Biological Chemistry, 261, 15679, 10.1016/S0021-9258(18)66771-7 Fujimoto, 1982, Adenosine diphosphate induces binding of von Willebrand factor to human platelets, Nature, 297, 154, 10.1038/297154a0 Fujimoto, 1982, Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets, Journal of Clinical Investigation, 69, 1212, 10.1172/JCI110560 Fujimura, 1986, Von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib, Journal of Biological Chemistry, 261, 381, 10.1016/S0021-9258(17)42483-5 Fujimura, 1987, A heparin-binding domain of human von Willebrand factor. Characterization and localization to a tryptic fragment extending from amino acid residue VAL-449 to LYS-728, Journal of Biological Chemistry, 262, 1734, 10.1016/S0021-9258(19)75700-7 Fuster, 1978, Resistance to arteriosclerosis in pigs with von Willebrand's disease. Spontaneous and high cholesterol diet-induced arteriosclerosis, Journal of Clinical Investigation, 61, 722, 10.1172/JCI108985 Giddings, 1986, Von Willebrand factor—physiology, 142 Giddings, 1983, Differential localisation and synthesis of porcine factor VIII related antigen (VIIIR: AG) in vascular endothelium and in endothelial cells in culture, Thrombosis Research, 29, 299, 10.1016/0049-3848(83)90042-7 Gill, 1987, The effect of ABO blood group on the diagnosis of von Willebrand disease, Blood, 69, 1691, 10.1182/blood.V69.6.1691.1691 Ginsburg, 1985, Human von Willebrand factor (vWF) isolation of complementary DNA (cDNA) clones and chromosomal localization, Science, 228, 1401, 10.1126/science.3874428 Girma, 1986, Limited proteolysis of human von Willebrand factor by Staphylococcus aureus V-8 protease: isolation and partial characterization of a platelet-binding domain, Biochemistry, 25, 3156, 10.1021/bi00359a013 Girma, 1986, Mapping of distinct von Willebrand factor domains interacting with platelet GPIb and GPIIb/IIIa and with collagen using monoclonal antibodies, Blood, 67, 1356, 10.1182/blood.V67.5.1356.1356 Gralnick, 1985, In vitro correction of the abnormal multimeric structure of von Willebrand factor in type IIa von Willebrand's disease, 82, 5968 Gralnick, 1985, von Willebrand's disease with spontaneous platelet aggregation induced by an abnormal plasma von Willebrand factor, Journal of Clinical Investigation, 76, 1522, 10.1172/JCI112132 Gralnick, 1986, DDAVP in type IIa von Willebrand's disease, Blood, 67, 465, 10.1182/blood.V67.2.465.465 Gralnick, 1987, A variant of type II von Willebrand's disease with an abnormal triplet structure and discordant effects of protease inhibitors on plasma and platelet von Willebrand factor structure, American Journal of Hematology, 24, 259, 10.1002/ajh.2830240305 Griggs, 1981, Susceptibility to atherosclerosis in aortas and coronary arteries of swine with von Willebrand's disease, American Journal of Pathology, 102, 137 Hamer, 1987, Factor VIII binds to von Willebrand factor via its Mr-80 000 light chain, European Journal of Biochemistry, 166, 37, 10.1111/j.1432-1033.1987.tb13480.x Hamer, 1987, The effect of thrombin on the complex between factor VIII and von Willebrand factor, European Journal of Biochemistry, 167, 253, 10.1111/j.1432-1033.1987.tb13331.x Hamilton, 1985, Effects of plasmin on von Willebrand factor multimers: degradation in vitro and stimulation of release in vivo, Journal of Clinical Investigation, 76, 261, 10.1172/JCI111956 Haverstick, 1985, Inhibition of platelet adhesion to fibronectin, fibrinogen and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin, Blood, 66, 946, 10.1182/blood.V66.4.946.946 Hill, 1985, Investigation of a kindred with a new autosomal dominantly inherited variant type von Willebrand's disease (possible type IID), Journal of Clinical Pathology, 38, 665, 10.1136/jcp.38.6.665 Holmberg, 1983, Platelet aggregation induced by 1-desamino-8-d-arginine vasopressin (DDAVP) in type IIB von Willebrand's disease, New England Journal of Medicine, 309, 816, 10.1056/NEJM198310063091402 Holmberg, 1986, Von Willebrand's disease characterized by increased ristocetin sensitivity and the presence of all von Willebrand factor multimers in plasma, Blood, 68, 668, 10.1182/blood.V68.3.668.668 Hormia, 1983, Factor VIII-related antigen. A pericellular matrix component of cultured human endothelial cells, Experimental Cell Research, 149, 483, 10.1016/0014-4827(83)90360-9 Houdijk, 1985, Role of factor VIII-von Willebrand factor and fibronectin in the interaction of platelets in flowing blood with monomeric and fibrillar human collagen types I and III, Journal of Clinical Investigation, 75, 531, 10.1172/JCI111729 Houdijk, 1986, Subendothelial proteins and platelet adhesion. Von Willebrand factor and fibronectin, not thrombospondin, are involved in platelet adhesion to extracellular matrix of human vascular endothelial cells, Arteriosclerosis, 6, 24, 10.1161/01.ATV.6.1.24 Houdijk, 1986, Comparison of tryptic fragments of von Willebrand factor involved in binding to thrombin-activated platelets with fragments involved in ristocetin-induced binding and binding to collagen, Thrombosis and Haemostasis, 56, 391, 10.1055/s-0038-1661689 Howard, 1982, Variant von Willebrand's disease type B-revisited, Blood, 60, 1420, 10.1182/blood.V60.6.1420.1420 Hoyer, 1980, Factor VIII-related protein circulates in normal human plasma as high molecular weight multimers, Blood, 55, 1056, 10.1182/blood.V55.6.1056.1056 Hoyer, 1983, Von Willebrand factor multimer patterns in von Willebrand's disease, British Journal of Haematology, 55, 493, 10.1111/j.1365-2141.1983.tb02165.x Iannuzzi, 1987, Rsa1 RFLP in the human von Willebrand factor gene, Nucleic Acids Research, 15, 5909, 10.1093/nar/15.14.5909 Ingram, 1974, Four cases of acquired von Willebrand's syndrome, Blood, 21, 189 Jaffe, 1974, Synthesis of von Willebrand factor by cultured human endothelial cells, 71, 1906 Jorieux, 1987, Evidence that NH2-terminal but not COOH-terminal moiety of plasma von Willebrand factor binds to factor VIII, Thrombosis Research, 48, 205, 10.1016/0049-3848(87)90417-8 Kalafatis, 1987, Localization of a collagen-interactive domain of human von Willebrand factor between amino acid residue Gly 911 and Glu 1365, Blood, 70, 1577, 10.1182/blood.V70.5.1577.1577 Kinoshita, 1984, A new variant of dominant type II von Willebrand's disease with aberrant multimeric pattern of factor VIII-related antigen (type IID), Blood, 63, 1369, 10.1182/blood.V63.6.1369.1369 Koedam, 1988, Inactivation of human factor VIII by activated protein C. Cofactor activity of proteins and protective effect of von Willebrand factor, Journal of Clinical Investigation, 82, 1236, 10.1172/JCI113721 Konkle, 1987, Sac1 RFLP in the human von Willebrand factor gene, Nucleic Acids Research, 15, 6766, 10.1093/nar/15.16.6766 Koutts, 1978, Active release of human platelet factor VIII-related antigen by adenosine diphosphate, collagen and thrombin, Journal of Clinical Investigation, 62, 1255, 10.1172/JCI109246 Kozak, 1986, Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes, Cell, 44, 283, 10.1016/0092-8674(86)90762-2 Kunicki, 1988, The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complex, Journal of Biological Chemistry, 263, 4516, 10.1016/S0021-9258(18)68811-8 LaDuca, 1986, Platelet-collagen interaction: inhibition by ristocetin and enhancement by von Willebrand factor-platelet binding, Blood, 68, 927, 10.1182/blood.V68.4.927.927 LaDuca, 1987, Platelet-collagen adhesion enhances platelet aggregation induced by binding of vWF to platelets, American Journal of Physiology, 253, 1208 Lam, 1987, Evidence that arginyl-glycyl-aspartate peptides and fibrinogen γ chain peptides share a common binding site on platelets, Journal of Biological Chemistry, 262, 947, 10.1016/S0021-9258(19)75730-5 Lavergne, 1987, A second Xba1 polymorphic site within the human von Willebrand factor (vWF) gene, Nucleic Acids Research, 15, 9099, 10.1093/nar/15.21.9099 Lavergne, 1988, A Taq I polymorphism in the 5′ region of the von Willebrand factor (vWF) gene, Nucleic Acids Research, 16, 2742, 10.1093/nar/16.6.2742 Lawrence, 1987, Asialo-von Willebrand factor inhibits platelet adherence to human arterial subendothelium: discrepancy between ristocetin cofactor activity and primary hemostatic function, Blood, 70, 1084, 10.1182/blood.V70.4.1084.1084 Legaz, 1973, Isolation and characterization of human factor VIII (antihemophilic factor), Journal of Biological Chemistry, 248, 3946, 10.1016/S0021-9258(19)43824-6 Levine, 1982, Thrombin-mediated release of factor VIII antigen from human umbilical vein endothelial cells in culture, Blood, 60, 531, 10.1182/blood.V60.2.531.531 Loesberg, 1983, The effect of calcium on the secretion of factor VIII-related antigen by cultured human endothelial cells, Biochimica et Biophysica Acta, 763, 160, 10.1016/0167-4889(83)90039-3 Lynch, 1983, Biosynthesis of the subunits of factor VIIIR by bovine aortic endothelial cells, 80, 2738 McCarroll, 1984, The effect of DDAVP on plasma levels of von Willebrand Antigen II in normal individuals and patients with von Willebrand's disease, Blood, 63, 532, 10.1182/blood.V63.3.532.532 McCarroll, 1985, Endothelial cell synthesis of von Willebrand antigen II, von Willebrand factor and von Willebrand factor/von Willebrand antigen II complex, Journal of Clinical Investigation, 75, 1089, 10.1172/JCI111802 Madaras, 1978, Isolation and insolubilisation of human factor VIII by affinity chromatography, Haemostasis, 7, 321 Mancuso, 1987, Molecular cloning and structure of the human gene for von Willebrand factor, Blood, 70, 391a Mannucci, 1976, Precipitating antibodies in von Willebrand's disease, Nature, 262, 141, 10.1038/262141a0 Mannucci, 1977, 1-deamino-8-d-arginine vasopressin: a new pharmacological approach to management of haemophilia and von Willebrand's disease, Lancet, i, 869, 10.1016/S0140-6736(77)91197-7 Mannucci, 1983, A variant of von Willebrand's disease characterized by recessive inheritance and missing triplet structure of von Willebrand factor multimers, Blood, 62, 1000, 10.1182/blood.V62.5.1000.1000 Mannucci, 1984, Atherosclerosis and von Willebrand factor. I. 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A new plasma and platelet antigen deficient in severe von Willebrand's disease, Journal of Clinical Investigation, 61, 1498, 10.1172/JCI109070 Montgomery, 1986, Hereditary persistence of circulating pro von Willebrand factor (pro-vWf), Circulation, 74, 406 Morton, 1983, The interaction between collagens and factor VIII/von Willebrand factor: investigation of the structural requirements for interaction, Thrombosis Research, 32, 545, 10.1016/0049-3848(83)90056-7 Myerowitz, 1987, A deletion involving Alu sequences in the β-hexosaminidase α-chain gene of French Canadians with Tay-Sachs disease, Journal of Biological Chemistry, 262, 15396, 10.1016/S0021-9258(18)47738-1 Nachman, 1977, Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes, Journal of Clinical Investigation, 60, 914, 10.1172/JCI108846 Ngo, 1988, Homozygous and heterozygous deletions of the von Willebrand factor gene in patients and carriers of severe von Willebrand disease, 85, 2753 Nieuwenhuis, 1985, Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia, Nature, 318, 470, 10.1038/318470a0 Nieuwenhuis, 1986, Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading, Blood, 68, 692, 10.1182/blood.V68.3.692.692 Nishino, 1986, A polymorphism of the human von Willebrand factor (vWf) gene with GamHI, Nucleic Acids Research, 14, 4697, 10.1093/nar/14.11.4697 Nurden, 1983, Molecular defects of platelets in Bernard-Soulier syndrome, Blood Cells, 9, 333 O'Connell, 1987, A primary genetic linkage map for human chromosome 12, Genomics, 1, 93, 10.1016/0888-7543(87)90110-8 Ohmori, 1982, Electron microscopy of human factor VIII/von Willebrand glycoprotein: effect of reducing reagents on structure and function, Journal of Cell Biology, 95, 632, 10.1083/jcb.95.2.632 Pareti, 1986, Isolation and characterization of a collagen binding domain in human von Willebrand factor, Journal of Biological Chemistry, 261, 15310, 10.1016/S0021-9258(18)66869-3 Pareti, 1987, Isolation and characterization of two domains of human von Willebrand factor that interact with fibrillar collagen types I and III, Journal of Biological Chemistry, 262, 13835, 10.1016/S0021-9258(19)76501-6 Parker, 1986, Identification of platelet glycoprotein IIb/IIIa as the major binding site for released platelet-von Willebrand factor, Blood, 68, 732, 10.1182/blood.V68.3.732.732 Perlino, 1987, The human α1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes, Embo Journal, 6, 2767, 10.1002/j.1460-2075.1987.tb02571.x Perret, 1979, Studies on factor VIII-related protein. 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