4D flow MRI
Tóm tắt
Traditionally, magnetic resonance imaging (MRI) of flow using phase contrast (PC) methods is accomplished using methods that resolve single‐directional flow in two spatial dimensions (2D) of an individual slice. More recently, three‐dimensional (3D) spatial encoding combined with three‐directional velocity‐encoded phase contrast MRI (here termed 4D flow MRI) has drawn increased attention. 4D flow MRI offers the ability to measure and to visualize the temporal evolution of complex blood flow patterns within an acquired 3D volume. Various methodological improvements permit the acquisition of 4D flow MRI data encompassing individual vascular structures and entire vascular territories such as the heart, the adjacent aorta, the carotid arteries, abdominal, or peripheral vessels within reasonable scan times. To subsequently analyze the flow data by quantitative means and visualization of complex, three‐directional blood flow patterns, various tools have been proposed. This review intends to introduce currently used 4D flow MRI methods, including Cartesian and radial data acquisition, approaches for accelerated data acquisition, cardiac gating, and respiration control. Based on these developments, an overview is provided over the potential this new imaging technique has in different parts of the body from the head to the peripheral arteries. J. Magn. Reson. Imaging 2012;36:1015–1036. © 2012 Wiley Periodicals, Inc.
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Tài liệu tham khảo
Hahn EL, 1960, Detection of sea water motion by nuclear precession, J Geophys Res, 65
Pelc NJ, 1991, Phase contrast cine magnetic resonance imaging, Magn Reson Q, 7, 229
Firmin DN, 1993, Rapid 7‐dimensional imaging of pulsatile flow, Comput Cardiol IEEE Comput Soc Lond, 14, 353
Gu T, 2005, PC VIPR: a high‐speed 3D phase‐contrast method for flow quantification and high‐resolution angiography, AJNR Am J Neuroradiol, 26, 743
Turk AS, 2007, Physiologic and anatomic assessment of a canine carotid artery stenosis model utilizing phase contrast with vastly undersampled isotropic projection imaging, AJNR Am J Neuroradiol, 28, 111
BleyTA JohnsonKM WiebenO et al.Non‐invasive assessment of transstenotic pressure gradients utilizing 3D phase contrast MRA: validation against endovascular pressure measurements in a porcine study. In: Proc 17th Annual Meeting ISMRM Honolulu;2009:425.
Nakano S, 1999, Pharmacologically stimulated portal flow measurement by magnetic resonance imaging for assessment of liver function, Radiat Med, 17, 21
NettEJ FrydrychowiczA JohnsonKM SchraubenE FrancoisCJ WiebenO.Accelerated dual Venc phase contrast VIPR in healthy volunteers. In: Proc 19th Annual Meeting ISMRM Montreal;2011:1222.
Wetzel S, 2007, In vivo assessment and visualization of intracranial arterial hemodynamics with flow‐sensitized 4D MR imaging at 3T, AJNR Am J Neuroradiol, 28, 433