4 Immunology of inflammatory bowel disease

Adeyemi, 1985, Circulating human leucocyte elastase in patients with inflammatory bowel disease, Gut, 26, 1306, 10.1136/gut.26.12.1306 Allison, 1984, Cyclosporin for Crohn's disease, Lancet, i, 902, 10.1016/S0140-6736(84)91358-8 Bagchi, 1984, Detection and partial characterization of Crohn's disease specific tissue protein recognized in Crohn's disease sera, Clinical and Experimental Immunology, 55, 41 Biemond, 1986, HLA A and B antigens in inflammatory bowel disease, Gut, 26, 934, 10.1136/gut.27.8.934 Boughton-Smith, 1983, Biosynthesis of lipoxygenase and cyclooxygenase products from (14-C) arachidonic acid by human colonic mucosa, Gut, 24, 1176, 10.1136/gut.24.12.1176 Bull, 1979, Isolation and functional characterisation of human intestinal mucosal lymphoid cells, Journal of Clinical Investigation, 59, 966, 10.1172/JCI108719 Campbell, 1976, Immuno-suppression in the treatment of inflammatory bowel disease—II, 24, 249 Das, 1983, Studies of the aetiology of Crohn's disease using nude mice, Gastroenterology, 84, 364, 10.1016/S0016-5085(83)80135-8 Eade, 1980, Discordant HLA haplotype segregation in familial Crohn's disease, Gastroenterology, 79, 271, 10.1016/0016-5085(80)90140-7 Ebert, 1984, T cells in inflammatory bowel disease demonstrate diminished production of and response to interleukin-2, Gastroenterology, 86, 1068 Elmgreen, 1983, Hypercatabolism of complement in Crohn's disease—assessment of circulating C3c, Acta Medica Scandinavica, 214, 403, 10.1111/j.0954-6820.1983.tb08615.x Elmgreen, 1983, Defective release of C5a related chemo attractant activity from complement in Crohn's disease, Gut, 24, 525, 10.1136/gut.24.6.525 Elson, 1980, An evaluation of total parenteral nutrition in the management of inflammatory bowel disease, Digestive Diseases and Sciences, 25, 42, 10.1007/BF01312731 Elson, 1984, Hypogammaglobulinaemia due to abnormal suppressor T-cell activity in Crohn's disease, Gastroenterology, 86, 569, 10.1016/S0016-5085(84)80030-X Elson, 1985, T cell-B cell regulation in the intestinal lamina propria in Crohn's disease, Gastroenterology, 89, 321, 10.1016/0016-5085(85)90332-4 Fiocchi, 1981, Studies on isolated gut mucosal lymphocytes in inflammatory bowel disease, 26, 728 Fiocchi, 1984, Interleukin 2 activity of human intestinal mucosa mononuclear cells, Gastroenterology, 86, 734, 10.1016/S0016-5085(84)80124-9 Fiocchi, 1983, Immunoregulatory function of human intestinal mucosa lymphoid cells: evidence for enhanced suppressor cell activity in inflammatory bowel disease, Gut, 24, 692, 10.1136/gut.24.8.692 Galucci, 1982, The fine structure of human rectal epithelium in acute graft-versus-host disease, American Journal of Surgical Pathology, 6, 293, 10.1097/00000478-198206000-00002 Gibson, 1986, Local immune mechanisms in inflammatory bowel disease and colorectal carcinoma, Gastroenterology, 90, 12, 10.1016/0016-5085(86)90068-5 Ginsburg, 1982, Defective autologous mixed-lymphocyte reaction and suppressor cell generation in patients with inflammatory bowel disease, Gastroenterology, 83, 1, 10.1016/S0016-5085(82)80276-X Goodacre, 1982, Reduced suppressor cell activity in intestinal lymphocytes from patients with Crohn's disease, Gastroenterology, 82, 653, 10.1016/0016-5085(82)90307-9 Gupta, 1984, Cyclosporin in ulcerative colitis, Lancet, ii, 1277, 10.1016/S0140-6736(84)92826-5 Harries, 1984, Influence of nutritional status on immune functions in patients with Crohn's disease, Gut, 25, 465, 10.1136/gut.25.5.465 Heddle, 1979, Serum antibodies to Escherichia coli in subjects with ulcerative colitis, Clinical and Experimental Immunology, 38, 22 Helphingstone, 1979, Antibodies detectable by counter immunoelectrophoresis against bacteroides antigens in serum of patients with inflammatory bowel disease, Journal of Clinical Microbiology, 9, 373, 10.1128/jcm.9.3.373-378.1979 Hodgson, 1983, 86 Hodgson, 1978, Immune-complex mediated colitis in rabbits, Gut, 19, 225, 10.1136/gut.19.3.225 Hodgson, 1978, Decreased suppressor cell activity in inflammatory bowel disease, Clinical and Experimental Immunology, 32, 451 Holdstock, 1981, Increased suppressor cell activity in inflammatory bowel disease, Gut, 22, 1025, 10.1136/gut.22.12.1025 Holdstock, 1982, HLA B8 and granuloma formation in Crohn's disease, Gut, 23, 600, 10.1136/gut.23.7.600 Holdstock, 1982, Functional suppressor T-cell activity in Crohn's disease and the effects of sulphasalazine, Clinical and Experimental Immunology, 48, 619 James, 1986, Phenotypic analysis of lamina propria T-cells, Gastroenterology, 91, 1483, 10.1016/0016-5085(86)90205-2 Jewell, 1985, Immunology of inflammatory bowel disease, Scandinavian Journal of Gastroenterology, 20, 119, 10.3109/00365528509093772 Jewell, 1974, Azathioprine in ulcerative colitis: final report on a controlled therapeutic trial, British Medical Journal, ii, 627, 10.1136/bmj.4.5945.627 Jones, 1985, Crohn's disease: maintenance of remission by diet, Lancet, ii, 177, 10.1016/S0140-6736(85)91497-7 Kagnoff, 1983, Association between Crohn's disease and immunoglobulin heavy chain (Gm) allotypes, Gastroenterology, 85, 1044, 10.1016/S0016-5085(83)80069-9 Kirk, 1982, Controlled trial of azathioprine in chronic ulcerative colitis, British Medical Journal, 284, 1291, 10.1136/bmj.284.6325.1291 Lauritsen, 1984, Effects of sulphasalazine and disodium azodisalicylate on colonic PGE2 concentration determined by equilibrium in vivo dialysis of faeces in patients with ulcerative colitis and healthy controls, Gut, 25, 1271, 10.1136/gut.25.11.1271 Ligumsky, 1981, Enhanced thromboxane A2 and prostacyclin production by rectal mucosa in ulcerative colitis and its inhibition by steroids and sulphasalazine, Gastroenterology, 81, 444, 10.1016/0016-5085(81)90594-1 Logan, 1981, Reduction of gastrointestinal protein loss by elemental diet in Crohn's disease of the small bowel, Gut, 22, 383, 10.1136/gut.22.5.383 MacDermott, 1981, Alterations of IgM, IgG and IgA synthesis and secretion by peripheral blood and intestinal mononuclear cells from patients with ulcerative colitis and Crohn's disease, Gastroenterology, 81, 844, 10.1016/S0016-5085(81)80107-2 Mahida, 1986, Macrophage subpopulations in inflammatory bowel disease, Gut, 27, A1245 Marcussen, 1978, Fluorescent anti-colonic and E. coli antibodies in ulcerative colitis, Scandinavian Journal of Gastroenterology, 13, 277, 10.3109/00365527809179820 Mayberry, 1984, Epidemiological aspects of Crohn's disease: a review of the literature, Gut, 25, 886, 10.1136/gut.25.8.886 Mayberry, 1979, Incidence of Crohn's disease in Cardiff between 1934–1977, Gut, 20, 602, 10.1136/gut.20.7.602 McDonald, 1987, Class II antigen (HLA-DR) expression by intestinal epithelial cells in inflammatory diseases of colon, Journal of Clinical Pathology, 10.1136/jcp.40.3.312 Mee, 1979, Atopy of inflammatory bowel disease, Scandinavian Journal of Gastroenterology, 14, 743, 10.3109/00365527909181947 Mee, 1979, Chronic immune colitis in rabbits, Gut, 20, 1, 10.1136/gut.20.1.1 Monteiro, 1971, Antibacterial antibodies in rectal and colonic mucosa in ulcerative colitis, Lancet, i, 249, 10.1016/S0140-6736(71)90997-4 Nagai, 1981, Detection of colonic antigen(s) in tissues from ulcerative colitis using purified colitis colon tissue bound IgG, Gastroenterology, 81, 463, 10.1016/0016-5085(81)90597-7 O'Donoghue, 1978, Doubleblind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease, Lancet, ii, 955, 10.1016/S0140-6736(78)92524-2 O'Morain, 1984, Elemental diet as primary treatment of acute Crohn's disease: a controlled trial, British Medical Journal, 288, 1859, 10.1136/bmj.288.6434.1859 Otto, 1973, The interepithelial lymphocytes of the intestine: morphological observations and immunological aspects of intestinal enteropathy, Current Topics in Pathology, 57, 81 Pena, 1986, Seropositivity in Dutch Crohn's disease patients against primed nude mice lymph nodes, and the différence with cytotoxic antibodies, Gut, 27, 1426, 10.1136/gut.27.12.1426 Podolsky, 1983, Composition of human colonic mucin, 72, 142 Rhodes, 1985, Histochemical demonstration of desialation and desulphation of normal and inflammatory bowel disease rectal mucus by faecal extracts, Gut, 26, 1312, 10.1136/gut.26.12.1312 Saverymuttu, 1982, Indium111 autologous leucocyte scanning: comparison with radiology for imaging the colon in inflammatory bowel disease, British Medical Journal, 285, 255, 10.1136/bmj.285.6337.255 Saverymuttu, 1982, 111-In-leucocytes, a new method of imaging the colon in inflammatory bowel disease, British Medical Journal, 285, 225, 10.1136/bmj.285.6337.255 Saverymuttu, 1983, Assessment of disease activity in inflammatory bowel disease: a new approach using Indium111 granulocyte scanning, British Medical Journal, 287, 1751, 10.1136/bmj.287.6407.1751 Schrumpf, 1982, HLA antigens and immunoregulatory T-cells in ulcerative colitis associated with hepatobiliary disease, Scandinavian Journal of Gastroenterology, 17, 187, 10.3109/00365528209182038 Scott, 1986, Spontaneous secretion of IgG subclasses by intestinal mononuclear cells: différences between ulcerative colitis, Crohn's disease and controls, Clinical and Experimental Immunology, 66, 209 Selby, 1983, Heterogeneity of HLA-DRpositive histiocytes in human intestinal lamina propria: a combined histochemical and immunohistological analysis, Journal of Clinical Pathology, 36, 379, 10.1136/jcp.36.4.379 Sharon, 1983, Production of leukotrienes by colonic mucosa from patients with inflammatory bowel disease, Gastroenterology, 84, 1306 Shorter, 1969, Further studies of in vitro cytotoxicity of lymphocytes from patients with ulcerative and granulomatous colitis, Gastroenterology, 65, 304, 10.1016/S0016-5085(69)80129-0 Shorter, 1984, Cytotoxicity of mononuclear cells for autologous colonic epithelial cells in colonic diseases, Gastroenterology, 86, 13, 10.1016/0016-5085(84)90584-5 Strickland, 1980, Circulating interféron in active inflammatory bowel disease, Gastroenterology, 78, A1271 Summers, 1979, National co-operative Crohn's disease study: results of drug treatment, Gastroenterology, 77, 847, 10.1016/0016-5085(79)90385-8 Tysk, 1986, Inflammatory bowel disease in monozygotic and dizygotic twins, Scandinavian Journal of Gastroenterology, 21, 2 Victorino, 1982, Spontaneous suppressor cell function in inflammatory bowel disease, Digestive Diseases and Science, 26, 801, 10.1007/BF01309612 Wandell, 1982, Leucocyte function in Crohn's disease, 23, 173 Wandell, 1982, Leucocyte function in ulcerative colitis, 23, 758 Wilders, 1984, Veiled cells in chronic idiopathic inflammatory bowel disease, Clinical and Experimental Immunology, 55, 377 Wright, 1965, A controlled therapeutic trial of various diets in ulcerative colitis, British Medical Journal, ii, 138, 10.1136/bmj.2.5454.138