4-Hydroxynonenal from pathology to physiology

Albano, 1982, Spin trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions, isolated hepatocytes and in vivo, Biochem. J., 204, 593, 10.1042/bj2040593

Barrera, 1991, Effects of 4-hydroxynonenal, a product of lipid peroxidation, on cell proliferation and ornithine decarboxylase activity, Free Radical Res. Commun., 14, 81, 10.3109/10715769109094120

Barrera, 1996, Effect of 4-Hydroxynonenal on cell cycle progression and expression of differentiation-associated antigens in HL-60 cells, Free Radical Bio. Med., 20, 455, 10.1016/0891-5849(95)02049-7

Barrera, 2000, Cancer Detect. Prevent., 24, 244

Barrera, 2002, 4-Hydroxynonenal affects pRb/E2F pathway in HL-60 human leukemic cells, Biochem. Biophys. Res. Commun., 285, 267, 10.1016/S0006-291X(02)00649-6

Basu-Modak, 1996, Lipid metabolite involvement in the activation of the human heme oxygenase-1 gene, Free Radical Bio. Med., 20, 887, 10.1016/0891-5849(95)02182-5

Benedetti, 1980, Identifı̀cation of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids, Biochim. Biophys. Acta, 620, 281, 10.1016/0005-2760(80)90209-X

Cajone, 1989, The action of 4-hydroxynonenal on heat shock gene expression in cultured hepatoma cells, Free Radical Res. Commun., 7, 189, 10.3109/10715768909087941

Camandola, 1997, Biogenic 4-hydroxynonenal activates transcription factor AP-1 but not NF-kB in cells of the macrophage lineage, BioFactors, 6, 173, 10.1002/biof.5520060211

Camandola, 2000, The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons, J. Neurochem., 74, 159, 10.1046/j.1471-4159.2000.0740159.x

Chiarpotto, 1999, Regulation of rat hepatocyte protein kinase C beta isoenzymes by the lipid peroxidation product 4-hydroxy-2,3-nonenal: a signaling pathway to modulate vesicular transport of glycoproteins, Hepatology, 29, 1565, 10.1002/hep.510290510

Comporti, 1965, Effect of CCl4 in vitro and in vivo on lipid peroxidation of rat liver homogenates and sub-cellular fractions, Enzymologia, XXIX, 185

Curzio, 1982, Neutrophil chemotactic response to aldehydes, Res. Commun. Chem. Pathol. Pharm., 36, 463

Curzio, 1986, Chemotactic activity of the lipid peroxidation product 4-hydroxy-nonenal and homologous hydroxyalkenals, Biol. Chem. Hoppe Seyler’s, 367, 321, 10.1515/bchm3.1986.367.1.321

Dianzani, 1954, Uncoupling of oxidative phosphorylation in mitochondria from fatty livers, Biochim. Biophys. Acta, 14, 514, 10.1016/0006-3002(54)90232-2

Dianzani, 1955, Content and distribution of pyridine nucleotides in fatty livers, Biochim. Biophys. Acta, 17, 391, 10.1016/0006-3002(55)90388-7

Dianzani, 1961, Ricerche sulle proteine mutocondriali, Therapeutikon, I, 5

Dianzani, 1955, The content and distribution of cytochrome c in fatty livers, Biochem. J., 59, 141, 10.1042/bj0590141

Esterbauer, 1982, Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP/Fe2+ in rat liver microsomes, Biochem. J., 208, 129, 10.1042/bj2080129

Fazio, 1992, 4-Hydroxynonenal, a product of cellular lipid peroxidation, which modulates c-myc and globin gene expression in K562 erythroleukemic cells, Cancer Res., 52, 4866

Ghoshal, 1965, Positive evidence of acceleration of lipoperoxidatı́on in rat liver by carbon tetrachloride: in vitro experiments, Life Sci., 4, 152, 10.1016/0024-3205(65)90173-6

Leonarduzzi, 1997, The lipid peroxidation end product 4-hydroxy-2,3-nonenal up-regulates transforming growth factor beta1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis, FASEB J., 11, 851, 10.1096/fasebj.11.11.9285483

Liu, 1998, Gamma-glutamylcysteine synthetase: mRNA stabilization and independent subunit transcription by 4-hydroxy-2-nonenal, Am. J. Physiol., 275, L861

Marra, 1999, Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E, J. Investig. Med., 47, 66

Paradisi, 1985, Effects of 4-hydroxynonenal in adenylate cyclase and 5′-nucleotidase activities in rat liver plasma membranes, Chem. Biol. Interact., 53, 209, 10.1016/S0009-2797(85)80097-1

Parola, 1992, Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis, Hepatology, 16, 1014, 10.1002/hep.1840160426

Parola, 1992, Vitamin E dietary supplementation inhibits transforming growth factor β I gene expression in the rat liver, FEBS, 308, 267, 10.1016/0014-5793(92)81290-3

Parola, 1993, Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen α1(I) gene expression and synthesis in human liver fat-storing cells, Biochem. Biophys. Res. Commun., 194, 1044, 10.1006/bbrc.1993.1927

Parola, 1998, HNE interacts directly with JNK isoforms in human hepatic stellate cells, J. Clin. Invest., 102, 1942, 10.1172/JCI1413

Pizzimenti, 1999, Inhibition of D1, D2, and A-cyclin expression in HL-60 cells by the lipid peroxydation product 4-hydroxynonenal, Free Radical Bio. Med., 26, 1578, 10.1016/S0891-5849(99)00022-2

Poli, 1985, Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP iron in isolated rat hepatocytes and rat liver microsomal suspensions, Biochem. J., 227, 638, 10.1042/bj2270629

Rinaldi, 2000, 4-Hydroxynonenal-induced MEL cell differentiation involves PKC activity translocation, Biochem. Biophys. Res. Commun., 272, 75, 10.1006/bbrc.2000.2691

Robino, 2000, Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor β receptor. Reduced tyrosine phosphorylation and down-stream signaling in hepatic stellate cells, J. Biol. Chem., 275, 40461, 10.1074/jbc.M007694200

Rossi, 1988, Stimulation of 4-hydroxy-2,3-trans-nonenal, a lipid peroxidation production hepatic phospholipase C, J. Tissue React., 10, 323

Ruef, 1998, Induction of rat aortic smooth muscle cell growth by the lipid peroxidation product 4-hydroxy-2-nonenal, Circulation, 97, 1071, 10.1161/01.CIR.97.11.1071

Schauenstein, 1977, vol. 1, 133

Schaur, 1994, The lipid peroxidation product 4-hydroxynonenal is formed by––and is able to attract––rat neutrophils in vivo, Free Radical Res., 20, 365, 10.3109/10715769409145636

Slater, 1966, Necrogenic action of carbon tetrachloride in the rat: a speculative mechanism based on activation, Nature (Lond.), 209, 36, 10.1038/209036a0

Spycher, 1996, 4-Hydroxy-2,3-trans-nonenal induces transcription and expression of aldose reductase, Biochem. Biophys. Res. Commun., 226, 512, 10.1006/bbrc.1996.1386

Tamagno, 2002, Oxidative stress increases expression and activity of BACE in NT(2) neurons, Neurobiol. Dis., 10, 279, 10.1006/nbdi.2002.0515

Zamara, 2002, 4-Hydroxynonenal selectively up-regulates TIMP-1 gene expression in stellate cells, J. Hepatol., 36, 76, 10.1016/S0168-8278(02)80259-8