2019 EACTS Expert Consensus on long-term mechanical circulatory support

European Journal of Cardio-thoracic Surgery - Tập 56 Số 2 - Trang 230-270 - 2019
Evgenij Potapov1,2, Christiaan F J Antonides3, María G. Crespo‐Leiro4, Alain Combes5,6, Gloria Färber7, Margaret M. Hannan8, Marian Kukucka9, Nicolaas de Jonge10, Antonio Loforte11, Lars H. Lund12, Paul Mohaçsi13, Michiel Morshuis14, Ivan Netuka15, Mustafa Özbaran16, Federico Pappalardo17, Anna Mara Scandroglio18, Martin Schweiger19, Steven Tsui20, Daniel Zimpfer21, Finn Gustafsson22
1DZHK (German Centre for Cardiovascular Research), partner site, Berlin, Germany
2Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Germany
3Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands
4Complexo Hospitalario Universitario A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), CIBERCV, UDC, La Coruña, Spain
5Service de Médecine Intensive-Réanimation, Institut de Cardiologie, APHP Hôpital Pitié–Salpêtrière, Paris, France
6Sorbonne Université, INSERM, Institute of Cardiometabolism and Nutrition, Paris, France
7Department of Cardiothoracic Surgery, Jena University Hospital, Friedrich-Schiller-University of Jena, Jena, Germany
8Department of Medical Microbiology, University College of Dublin, Dublin, Ireland
9Department of Anaesthesiology, German Heart Center Berlin, Berlin, Germany
10Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands
11Department of Cardiothoracic, S. Orsola Hospital, Transplantation and Vascular Surgery, University of Bologna, Bologna, Italy
12Department of Medicine Karolinska Institute, Heart and Vascular Theme, Karolinska University Hospital, Solna, Sweden
13Department of Cardiovascular Surgery Swiss Cardiovascular Center, Inselspital, Bern University Hospital, Bern, Switzerland
14Clinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Germany
15Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic
16Department of Cardiovascular Surgery, Ege University, Izmir, Turkey
17Advanced Heart Failure and Mechanical Circulatory Support Program, Cardiac Intensive Care, San Raffaele Hospital, Vita Salute University, Milan, Italy
18Department of Anesthesia and Intensive Care, San Raffaele Hospital, Vita Salute University, Milan, Italy
19Department of Congenital Pediatric Surgery, Zurich Children's Hospital, Zurich, Switzerland
20Royal Papworth Hospital, Cambridge, United Kingdom
21Department of Surgery, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
22Department of Cardiology, Rigshospitalet, Copenhagen, Denmark

Tóm tắt

Abstract

Long-term mechanical circulatory support (LT-MCS) is an important treatment modality for patients with severe heart failure. Different devices are available, and many—sometimes contradictory—observations regarding patient selection, surgical techniques, perioperative management and follow-up have been published. With the growing expertise in this field, the European Association for Cardio-Thoracic Surgery (EACTS) recognized a need for a structured multidisciplinary consensus about the approach to patients with LT-MCS. However, the evidence published so far is insufficient to allow for generation of meaningful guidelines complying with EACTS requirements. Instead, the EACTS presents an expert opinion in the LT-MCS field. This expert opinion addresses patient evaluation and preoperative optimization as well as management of cardiac and non-cardiac comorbidities. Further, extensive operative implantation techniques are summarized and evaluated by leading experts, depending on both patient characteristics and device selection. The faculty recognized that postoperative management is multidisciplinary and includes aspects of intensive care unit stay, rehabilitation, ambulatory care, myocardial recovery and end-of-life care and mirrored this fact in this paper. Additionally, the opinions of experts on diagnosis and management of adverse events including bleeding, cerebrovascular accidents and device malfunction are presented. In this expert consensus, the evidence for the complete management from patient selection to end-of-life care is carefully reviewed with the aim of guiding clinicians in optimizing management of patients considered for or supported by an LT-MCS device.

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