1H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles

Marine Drugs - Tập 16 Số 10 - Trang 390
Laura Del Coco1, Fabrizio Serena2, Chiara Roberta Girelli1, Federica Angilè1, Laura Magliozzi3, Frederico Almada4, Biagio D’Aniello3, Ernesto Mollo5, Antonio Terlizzi2,6, Francesco Paolo Fanizzi1
1Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali (Di.S.Te.B.A.), Università del Salento, 73100 Lecce, Italy
2Consorzio Interuniversitario per le Scienze del Mare (CoNISMa), 00196 Roma, Italy
3Dipartimento di Biologia, Università Degli Studi di Napoli “Federico II”, 80126, Napoli, Italy
4MARE—Marine and Environmental Sciences Centre, ISPA—Instituto Universitário, 1140-041 Lisbon, Portugal
5Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, 80078, Pozzuoli, Italy
6Department of Biology and Evolution of Marine Organisms, Stazione Zoologica A. Dohrn, 80121 Napoli, Italy

Tóm tắt

The biological invasion of the green algae Caulerpa cylindracea represents a serious scientific and public issue in the Mediterranean Sea, essentially due to strong modifications both to habitat structure and native benthic communities. Although alterations in health status and changes in flesh quality of some marine species (dietary exposed to C. cylindracea) have been observed, no studies on cause-effect relationships have been carried out. Here, for the first time, through a controlled feeding experiment followed by 1H NMR Spectroscopy and multivariate analysis (PCA, OPLS-DA), we showed that caulerpin taken with diet is directly responsible of changes observed in metabolic profile of fish flesh, including alteration of lipid metabolism, in particular with a reduction of ω3 PUFA content. The potential of caulerpin to directly modulate lipid metabolism opens up new questions about causal mechanism triggered by algal metabolite also in view of a possible exploitation in the nutraceutical/medical field.

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Marine Drugs

Tập 16 Số 10

390

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