17β-Estradiol inhibits HIV-1 by inducing a complex formation between β-catenin and estrogen receptor α on the HIV promoter to suppress HIV transcription

Virology - Tập 443 - Trang 375-383 - 2013
Erika L. Szotek1, Srinivas D. Narasipura1, Lena Al-Harthi1
1Department of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA

Tài liệu tham khảo

Al-Harthi, 2012, Interplay between Wnt/beta-Catenin signaling and HIV: virologic and biologic consequences in the CNS, J. Neuroimmune Pharmacol., 7, 731, 10.1007/s11481-012-9411-y Asin, 2008, Estradiol and progesterone regulate HIV type 1 replication in peripheral blood cells, AIDS Res. Hum. Retroviruses, 24, 701, 10.1089/aid.2007.0108 Bakr, 2006, Higher clearance of hepatitis C virus infection in females compared with males, Gut, 55, 1183, 10.1136/gut.2005.078147 Brussel, 2003, Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus, J. Virol., 77, 10119, 10.1128/JVI.77.18.10119-10124.2003 Cao, 2009, Effects of resin or charcoal treatment on fetal bovine serum and bovine calf serum, Endocr. Res., 34, 101, 10.3109/07435800903204082 Delmas, 1997, Gender difference in CD4+ cell counts persist after HIV-1 infection. SEROCO Study Group, AIDS, 11, 1071 Fahey, 1999, Antigen-presenting cells in the human female reproductive tract: analysis of antigen presentation in pre- and post-menopausal women, Am. J. Reprod. Immunol., 42, 49, 10.1111/j.1600-0897.1999.tb00465.x Fahey, 2002, Effect of menstrual status on antibacterial activity and secretory leukocyte protease inhibitor production by human uterine epithelial cells in culture, J. Infect. Dis., 185, 1606, 10.1086/340512 Fung, 2013, Interferon-epsilon protects the female reproductive tract from viral and bacterial infection, Science, 339, 1088, 10.1126/science.1233321 Gandhi, 2002, Does patient sex affect human immunodeficiency virus levels?, Clin. Infect. Dis., 35, 313, 10.1086/341249 Gillgrass, 2010, Estradiol limits viral replication following intravaginal immunization leading to diminished mucosal IgG response and non-sterile protection against genital herpes challenge, Am. J. Reprod. Immunol., 63, 299, 10.1111/j.1600-0897.2009.00796.x Greenblatt, 2000, Impact of the ovulatory cycle on virologic and immunologic markers in HIV-infected women, J. Infect. Dis., 181, 82, 10.1086/315207 Hanna, 1999, The menstrual cycle and viral load, Beta, 12, 18 Harlow, 1995, Epidemiology of menstruation and its relevance to women's health, Epidemiol. Rev., 17, 265, 10.1093/oxfordjournals.epirev.a036193 Hayashida, 2010, 17beta-estradiol inhibits the production of infectious particles of hepatitis C virus, Microbiol. Immunol., 54, 684, 10.1111/j.1348-0421.2010.00268.x Heffron, 2012, Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study, Lancet Infect. Dis., 12, 19, 10.1016/S1473-3099(11)70247-X Henderson, 2012, Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, beta-Catenin, and SMAR1 to repress HIV transcription, J. Virol., 86, 9495, 10.1128/JVI.00486-12 Hou, 2004, Canonical Wnt signaling is critical to estrogen-mediated uterine growth, Mol. Endocrinol., 18, 3035, 10.1210/me.2004-0259 Huang, 2009, Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling, Nature, 461, 614, 10.1038/nature08356 James, 1992, Acceleration of adenovirus replication and increased virion production by treatment with the steroid hormone 17 beta-estradiol, Microbiol. Immunol., 36, 99, 10.1111/j.1348-0421.1992.tb01646.x Kaushic, 1998, Influence of the estrous cycle on the presence and distribution of immune cells in the rat reproductive tract, Am. J. Reprod. Immunol., 39, 209, 10.1111/j.1600-0897.1998.tb00355.x Kouzmenko, 2004, Wnt/{beta}-Catenin and estrogen signaling converge in vivo 10.1074/jbc.C400331200, J. Biol. Chem., 279, 40255, 10.1074/jbc.C400331200 Kumar, 2008, Active {beta}-catenin signaling is an inhibitory pathway of HIV replication in peripheral blood mononuclear cells, J. Virol., 82, 2813, 10.1128/JVI.02498-07 Lemly, 2009, Race and sex differences in antiretroviral therapy use and mortality among HIV-infected persons in care, J. Infect. Dis., 199, 991, 10.1086/597124 Li, 2011, IFN-{gamma} Mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the {beta}-catenin pathway (DKK1) in a STAT 3-dependent manner, J. Immunol., 186, 6771, 10.4049/jimmunol.1100099 Lu, 2002, The strength of B cell immunity in female rhesus macaques is controlled by CD8+ T cells under the influence of ovarian steroid hormones, Clin. Exp. Immunol., 128, 10, 10.1046/j.1365-2249.2002.01780.x Marino, 2006, Estrogen signaling multiple pathways to impact gene transcription, Curr. Genomics, 7, 497, 10.2174/138920206779315737 Meditz, 2011, Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection, J. Infect. Dis., 203, 442, 10.1093/infdis/jiq085 Meier, 2009, Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1, Nat. Med., 15, 955, 10.1038/nm.2004 Money, 2003, Genital tract and plasma human immunodeficiency virus viral load throughout the menstrual cycle in women who are infected with ovulatory human immunodeficiency virus, Am. J. Obstet. Gynecol., 188, 122, 10.1067/mob.2003.65 Murakami, 2013, Selective estrogen receptor modulators inhibit hepatitis C virus infection at multiple steps of the virus life cycle, Microbes Infect., 15, 45, 10.1016/j.micinf.2012.10.003 Narasipura, 2012, Role of beta-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes, J. Virol., 86, 1911, 10.1128/JVI.06266-11 Quayle, 1998, Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract, Am. J. Pathol., 152, 1247 Reichelderfer, 2000, Effect of menstrual cycle on HIV-1 levels in the peripheral blood and genital tract. WHS 001 Study Team, Aids, 14, 2101, 10.1097/00002030-200009290-00005 Reichelderfer, 2002, The menstrual cycle does not affect human immunodeficiency virus type 1 levels in vaginal secretions, J. Infect. Dis., 186, 726, 10.1086/342051 Rodriguez-Garcia, 2013, Innate and adaptive anti-HIV immune responses in the female reproductive tract, J. Reprod. Immunol., 97, 74, 10.1016/j.jri.2012.10.010 Roehrig, 1979, Effects of 17beta-estradiol on the replication of rubella virus in an estrogen-responsive, continuous cell line, J. Virol., 29, 417, 10.1128/JVI.29.1.417-420.1979 Saba, E., Origoni, M., Taccagni, G., Ferrari, D., Doglioni, C., Nava, A., Lisco, A., Grivel, J. C., Margolis, L., Poli, G., In press. Productive HIV-1 infection of human cervical tissue ex vivo is associated with the secretory phase of the menstrual cycle. Mucosal Immunol, 10.1038/mi.2013.2, [Epub ahead of print]. Shang, 2002, Molecular determinants for the tissue specificity of SERMs, Science, 295, 2465, 10.1126/science.1068537 Sterling, 1999, Sex differences in longitudinal human immunodeficiency virus type 1 RNA levels among seroconverters, J. Infect Dis., 180, 666, 10.1086/314967 Sterling, 2005, Sex-based differences in T lymphocyte responses in HIV-1-seropositive individuals, J. Infect. Dis., 191, 881, 10.1086/427827 Sterling, 2001, Initial plasma HIV-1 RNA levels and progression to AIDS in women and men, N Engl. J. Med., 344, 720, 10.1056/NEJM200103083441003 Vicetti Miguel, 2010, 17-beta estradiol promotion of herpes simplex virus type 1 reactivation is estrogen receptor dependent, J. Virol., 84, 565, 10.1128/JVI.01374-09 Villanueva, 2002, The menstrual cycle does not affect human immunodeficiency virus type 1 levels in vaginal secretions, J. Infect. Dis., 185, 170, 10.1086/338447 Wang, 2012, Estrogen receptor alpha represses transcription of HBV genes via interaction with hepatocyte nuclear factor 4alpha, Gastroenterology, 142, 989, 10.1053/j.gastro.2011.12.045 Weinberg, 2011, Effect of menstrual cycle variation in female sex hormones on cellular immunity and regulation, J. Reprod. Immunol., 89, 70, 10.1016/j.jri.2010.11.009