10 Coeliac disease research and clinical practice: maintaining momentum into the twenty-first century

Arranz, 1993, Intestinal antibody pattern of coeliac disease: occurrence in patients with normal jejunal biopsy histology, Gastroenterology, 104, 1263, 10.1016/0016-5085(93)90333-8 Arranz, 1994, Intestinal antibodies and intraepithelial lymphocytes in potential coeliac disease Arranz, 1994, Intestinal antibody pattern of coeliac disease: association with γδ T cell receptor expression by intraepithelial lymphocytes, and other indices of potential coeliac disease, Gut, 35, 476, 10.1136/gut.35.4.476 Booth, 1970, Concluding discussion, 244 Catassi, 1994, Coeliac disease in the year 2000: exploring the iceberg, Lancet, 343, 200, 10.1016/S0140-6736(94)90989-X 1989, ii, 777 Fais, 1992, Gliadin induced changes in the expression of MHC-class II antigens by human small intestinal epithelium, 33, 472 Ferguson, 1987, Models of immunologically-driven small intestinal damage, 225 Ferguson, 1971, Quantitation of intraepithelial lymphocytes in human jejunum, Gut, 12, 988, 10.1136/gut.12.12.988 Ferguson, 1977, Technique for microdissection and measurement in biopsies of human small intestine, Journal of Clinical Pathology, 30, 1068, 10.1136/jcp.30.11.1068 Ferguson, 1992, Definitions and diagnostic criteria of latent and potential coeliac disease, 119 Ferguson, 1993, Clinical and pathological spectrum of coeliac disease—active, silent, latent, potential, Gut, 34, 150, 10.1136/gut.34.2.150 Gawkrodger, 1991, Small intestinal function and dietary status in dermatitis herpetiformis, Gut, 32, 377, 10.1136/gut.32.4.377 Halstensen, 1993, Activated T lymphocytes in the celiac lesion: nonproliferative activation (CD25) of CD4+, α/β cells in the lamina propria but proliferation (Ki-67) of α/β and γ/δ cells in the epithelium, European Journal of Immunology, 23, 505, 10.1002/eji.1830230231 Halstensen, 1992, Association of subepithelial deposition of activated complement and immunoglobulin G and M response to gluten in celiac disease, Gastroenterology, 102, 751, 10.1016/0016-5085(92)90155-R Holm, 1992, Intraepithelial γ/δ T-cell receptor lymphocytes and genetic susceptibility to coeliac disease, Lancet, 339, 1500, 10.1016/0140-6736(92)91262-7 Holm, 1994, Immuno-histochemical changes in the jejunum in first-degree relatives of coeliac patients and the coeliac disease marker DQ genes, 35, 55 Howdle, 1981, Gluten sensitivity of small intestinal mucosa in vitro: quantitative assessment of histologic change, Gastroenterology, 80, 442, 10.1016/0016-5085(81)90004-4 Husby, 1995, Oral tolerance in humans. T cell but not B cell tolerance to a soluble protein antigen Lundin, 1993, Gliadin-specific, HLA (α1∗0501, β1∗0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients, Journal of Experimental Medicine, 178, 187, 10.1084/jem.178.1.187 MacDonald, 1976, Hypersensitivity reactions in the small intestine. 2. Effects of allograft rejection on mucosal architecture and lymphoid cell infiltrate, Gut, 17, 81, 10.1136/gut.17.2.81 Mäki, 1990, Normal small bowel biopsy followed by coeliac disease, Archives of Disease in Childhood, 65, 1137, 10.1136/adc.65.10.1137 Marsh, 1992, Gluten, major histocompatibility complex and the small intestine, Gastroenterology, 102, 330, 10.1016/0016-5085(92)91819-P Meuwisse, 1970, Diagnostic criteria in coeliac disease, Acta Paediatrica Scandinavica, 59, 461 Mowat, 1987, The regulation of immune responses to dietary protein antigens, Immunology Today, 8, 193, 10.1016/0167-5699(87)90853-X Mowat, 1982, Intraepithelial lymphocyte count and crypt hyperplasia measure the mucosal component of the graft-versus-host reaction in mouse small intestine, Gastroenterology, 83, 417, 10.1016/S0016-5085(82)80338-7 O'Mahony, 1990, Appraisal of gut lavage in the study of intestinal humoral immunity, Gut, 31, 1341, 10.1136/gut.31.12.1341 O'Mahony, 1990, Similarities in intestinal humoral immunity in dermatitis herpetiformis without enteropathy and in coeliac disease, Lancet, 335, 1487, 10.1016/0140-6736(90)93029-O Savilahti, 1992, Increase of lymphocytes bearing the γ/δ T cell receptor in the jejunum of patients with dermatitis herpetiformis, Gut, 33, 206, 10.1136/gut.33.2.206 Schmitz, 1992, Coeliac disease in childhood, 17 Sollid, 1993, HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis, Gastroenterology, 105, 910, 10.1016/0016-5085(93)90912-V Strobel, 1984, Cellobiose/mannitol sugar permeability test complements biopsy histopathology in clinical investigation of the jejunum, Gut, 25, 1241, 10.1136/gut.25.11.1241 Troncone, 1988, Gliadin presented via the gut induces oral tolerance in mice, Clinical and Experimental Immunology, 72, 284 Troncone, 1991, Anti-gliadin antibodies, Journal of Pediatric Gastroenterology and Nutrition, 12, 150, 10.1097/00005176-199102000-00002 Troncone, 1991, Animal model of gluten induced enteropathy in mice, Gut, 32, 871, 10.1136/gut.32.8.871 Walker-Smith, 1990, Revised criteria for diagnosis of coeliac disease, Archives of Disease in Childhood, 65, 909, 10.1136/adc.65.8.909 Weiner, 1993, Double blind pilot trial of oral tolerisation with myelin antigens in MS, Science, 259, 1321, 10.1126/science.7680493 Weinstein, 1974, Latent celiac sprue, Gastroenterology, 66, 489, 10.1016/S0016-5085(74)80034-X Wright, 1973, Cell kinetics in the flat (avillous) mucosa of the human small intestine, Gut, 20, 701, 10.1136/gut.14.9.701