1,2,3-Triazole tethered β-lactam-Chalcone bifunctional hybrids: Synthesis and anticancer evaluation

European Journal of Medicinal Chemistry - Tập 47 - Trang 594-600 - 2012
Pardeep Singh1, Raghu Raj1, Vipan Kumar1, Mohinder P. Mahajan2,1, Preet Mohinder Singh Bedi3, Tandeep Kaur4, Ajit Kumar Saxena4
1Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, India
2Apeejay Stya Research Foundation, Gurgaon, India
3Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, 143005, India
4Cancer Pharmacology Division, Indian Institute of Integrative Medicine, Jammu 180001, J & K, India

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Fadeyi, 2008, Bioorg. Med. Chem. Lett., 18, 4172, 10.1016/j.bmcl.2008.05.078

Rostom, 2006, Bioorg. Med. Chem., 14, 6475, 10.1016/j.bmc.2006.06.020

Chari, 1998, Adv. Drug Deliv. Rev., 31, 89, 10.1016/S0169-409X(97)00095-1

Sawyers, 2004, Nature, 432, 294, 10.1038/nature03095

Petrelli, 2008, Curr. Med. Chem., 15, 422, 10.2174/092986708783503212

Overington, 2006, Nat. Rev. Drug Discov., 5, 993, 10.1038/nrd2199

Szuromi, 2004, Science, 303, 1795, 10.1126/science.303.5665.1795

Bode, 2009, Nat. Rev. Cancer, 9, 508, 10.1038/nrc2646

Zhan, 2009, Curr. Pharm. Des., 15, 1893, 10.2174/138161209788453266

Morphy, 2005, J. Med. Chem., 48, 6523, 10.1021/jm058225d

Hopkins, 2008, Nat. Chem. Biol., 4, 682, 10.1038/nchembio.118

Viegas, 2007, Curr. Med. Chem., 14, 1829, 10.2174/092986707781058805

Walsh, 2009, Curr. Pharm. Des, 15, 2970, 10.2174/138161209789058183

Biot, 2006, Infect. Disord. Drug Targets, 6, 173, 10.2174/187152606784112155

Tietze, 2003, Angew. Chem. Int. Ed., 42, 3996, 10.1002/anie.200200553

Lee, 2007, Biochem. Pharmacol., 74, 870, 10.1016/j.bcp.2007.06.034

Nielsen, 2004, Bioorg. Med. Chem., 12, 3047, 10.1016/j.bmc.2004.03.071

Nielsen, 2005, J. Med. Chem., 48, 2667, 10.1021/jm049424k

Liu, 2005, Eur. Chem. Biodivers., 2, 1656, 10.1002/cbdv.200590135

Go, 2005, Curr. Med. Chem., 12, 483, 10.2174/0929867053363153

Edwards, 1990, J. Med. Chem., 33, 1948, 10.1021/jm00169a021

Ducki, 1998, Bioorg. Med. Chem. Lett., 8, 1051, 10.1016/S0960-894X(98)00162-0

Liu, 2001, J. Med. Chem., 44, 4443, 10.1021/jm0101747

Mishra, 2008, J. Med. Chem., 43, 1530

Domínguez, 2005, J. Med. Chem., 48, 3654, 10.1021/jm058208o

Domínguez, 2001, Eur. J. Med. Chem., 36, 555, 10.1016/S0223-5234(01)01245-4

Larsen, 2005, Bioorg. Med. Chem. Lett, 15, 4858, 10.1016/j.bmcl.2005.07.012

Go, 2004, Antimicrob. Agents Chemother., 48, 3241, 10.1128/AAC.48.9.3241-3245.2004

Lin, 2002, Bioorg. Med. Chem., 10, 2795, 10.1016/S0968-0896(02)00094-9

Friis-Moller, 2002, Planta Med., 68, 416, 10.1055/s-2002-32087

Chiaradia, 2008, Bioorg. Med. Chem. Lett., 18, 6227, 10.1016/j.bmcl.2008.09.105

Nowakowska, 2007, Eur. J. Med. Chem., 42, 125, 10.1016/j.ejmech.2006.09.019

Pettit, 2005, J. Med. Chem., 48, 4087, 10.1021/jm0205797

Kamal, 2011, Eur. J. Med. Chem., 1

Srinivasan, 2011, Bioorg. Med. Chem. Lett., 21, 555, 10.1016/j.bmcl.2010.10.063

Buckle, 1982, J. Chem. Soc., Perkin Trans., 1, 627, 10.1039/p19820000627

Buckle, 1983, J. Med. Chem., 26, 251, 10.1021/jm00356a025

Buckle, 1986, J. Med. Chem., 29, 2262, 10.1021/jm00161a022

Genin, 2000, J. Med. Chem., 43, 953, 10.1021/jm990373e

Nilkanth, 2009, Bioorg. Med. Chem. Lett., 19, 759, 10.1016/j.bmcl.2008.12.026

Alvarez, 1994, J. Med. Chem., 37, 4185, 10.1021/jm00050a015

Kelley, 1995, J. Med. Chem., 38, 4131, 10.1021/jm00020a030

Biagi, 1990, Farmacognosia, 45, 1181

Biagi, 1986, Farmacognosia, 41, 597

Micetich, 1987, J. Med. Chem., 30, 1469, 10.1021/jm00391a032

Kamal, 2008, Bioorg. Med. Chem. Lett., 18, 1468, 10.1016/j.bmcl.2007.12.063

Wang, 2010, Bioorg. Med. Chem. Lett., 20, 5979, 10.1016/j.bmcl.2010.08.093

He, 2010, J. Med. Chem., 53, 1347, 10.1021/jm901667k

Kolb, 2003, Drug Discov. Today, 8, 1128, 10.1016/S1359-6446(03)02933-7

Banik, 2010, Eur. J. Med. Chem., 45, 846, 10.1016/j.ejmech.2009.11.024

Banik, 2005, Bioorg. Med. Chem., 13, 3611, 10.1016/j.bmc.2005.03.044

O’Boyle, 2010, J. Med. Chem., 53, 8569, 10.1021/jm101115u

Carr, 2010, Eur. J. Med. Chem., 45, 5752, 10.1016/j.ejmech.2010.09.033

Singh, 2011, Bioorg. Med. Chem. Lett., 21, 4561, 10.1016/j.bmcl.2011.05.119

Singh, 2011, Bioorg. Med. Chem. Lett., 21, 3017, 10.1016/j.bmcl.2011.03.043

Raj, 2011, Eur. J. Org.Chem., 14, 2697, 10.1002/ejoc.201100130

Singh, 2011, Tetrahedron Lett., 52, 5060, 10.1016/j.tetlet.2011.07.089

Hans, 2010, Bioorg. Med. Chem. Lett., 20, 942, 10.1016/j.bmcl.2009.12.062

Monks, 1991, J. Natl. Cancer Inst., 83, 757, 10.1093/jnci/83.11.757

Skehan, 1990, J. Natl. Cancer Inst., 82, 1107, 10.1093/jnci/82.13.1107

Ferrara, 2002, Proteins: Struct., Funct., Bioinf., 46, 24, 10.1002/prot.10001

Ertl, 2000, J. Med. Chem., 43, 3714, 10.1021/jm000942e