Cryptococcusinteractions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen

Cellular Microbiology - Tập 15 Số 3 - Trang 403-411 - 2013
Simon A. Johnston1, Robin C. May2
1MRC Centre for Developmental and Biomedical Genetics Department of Biomedical Sciences University of Sheffield Sheffield S10 2TN UK
2Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK

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Alanio, 2011, Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans, MBio, 2, 4, 10.1128/mBio.00158-11

Alvarez, 2006, Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages, Curr Biol, 16, 2161, 10.1016/j.cub.2006.09.061

Alvarez, 2007, Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages, BMC Immunol, 8, 16, 10.1186/1471-2172-8-16

Arora, 2011, Effect of cytokine interplay on macrophage polarization during chronic pulmonary infection with Cryptococcus neoformans, Infect Immun, 79, 1915, 10.1128/IAI.01270-10

Artavanis-Tsakonas, 2006, Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification, Proc Natl Acad Sci USA, 103, 15945, 10.1073/pnas.0607528103

Bain, 2012, Non-lytic expulsion/exocytosis of Candida albicans from macrophages, Fungal Genet Biol, 49, 677, 10.1016/j.fgb.2012.01.008

Ben-Abdallah, 2012, Fungal-induced cell cycle impairment, chromosome instability and apoptosis via differential activation of NF-kappaB, PLoS Pathog, 8, e1002555, 10.1371/journal.ppat.1002555

Blackstock, 1997, Secretion of the C3 component of complement by peritoneal cells cultured with encapsulated Cryptococcus neoformans, Infect Immun, 65, 4114, 10.1128/IAI.65.10.4114-4121.1997

Bose, 2003, A yeast under cover: the capsule of Cryptococcus neoformans, Eukaryot Cell, 2, 655, 10.1128/EC.2.4.655-663.2003

Brown, 2007, Cryptococcus neoformans, a fungus under stress, Curr Opin Microbiol, 10, 320, 10.1016/j.mib.2007.05.014

Byrnes, 2010, Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States, PLoS Pathog, 6, e1000850, 10.1371/journal.ppat.1000850

Byrnes, 2011, A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients, PLoS Pathog, 7, e1002205, 10.1371/journal.ppat.1002205

Carnell, 2011, Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis, J Cell Biol, 193, 831, 10.1083/jcb.201009119

Casadevall, 2012, Amoeba provide insight into the origin of virulence in pathogenic fungi, Adv Exp Med Biol, 710, 1, 10.1007/978-1-4419-5638-5_1

Charlier, 2009, Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans, Infect Immun, 77, 120, 10.1128/IAI.01065-08

Chaturvedi, 2011, Cryptococcus gattii: a resurgent fungal pathogen, Trends Microbiol, 19, 564, 10.1016/j.tim.2011.07.010

Chayakulkeeree, 2011, SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans, Mol Microbiol, 80, 1088, 10.1111/j.1365-2958.2011.07632.x

Chun, 2011, A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans, Cell Host Microbe, 9, 243, 10.1016/j.chom.2011.02.003

Clarke, 2002, Dynamics of the vacuolar H(+)-ATPase in the contractile vacuole complex and the endosomal pathway of Dictyostelium cells, J Cell Sci, 115, 2893, 10.1242/jcs.115.14.2893

Crabtree, 2012, Titan cell production enhances the virulence of Cryptococcus neoformans, Infect Immun, 80, 3776, 10.1128/IAI.00507-12

Cross, 1995, Ingestion of acapsular Cryptococcus neoformans occurs via mannose and beta-glucan receptors, resulting in cytokine production and increased phagocytosis of the encapsulated form, Infect Immun, 63, 2604, 10.1128/IAI.63.7.2604-2611.1995

Davies, 1982, Opsonic requirements for the uptake of Cryptococcus neoformans by human polymorphonuclear leukocytes and monocytes, J Infect Dis, 145, 870, 10.1093/infdis/145.6.870

Deretic, 2012, Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors, Curr Opin Immunol, 24, 21, 10.1016/j.coi.2011.10.006

Diamond, 1973, Growth of Cryptococcus neoformans within human macrophages in vitro, Infect Immun, 7, 231, 10.1128/IAI.7.2.231-236.1973

Doering, 2009, How sweet it is! Cell wall biogenesis and polysaccharide capsule formation in Cryptococcus neoformans, Annu Rev Microbiol, 63, 223, 10.1146/annurev.micro.62.081307.162753

Doering, 1999, Melanin as a potential cryptococcal defence against microbicidal proteins, Med Mycol, 37, 175, 10.1080/j.1365-280X.1999.00218.x

Dromer, 2011, Cryptococcus: From Human Pathogen to Model Yeast, 465, 10.1128/9781555816858.ch34

Dromer, 2011, Cryptococcus: From Human Pathogen to Model Yeast, 431, 10.1128/9781555816858.ch31

Eisenman, 2007, Cryptococcus neoformans laccase catalyses melanin synthesis from both D- and L-DOPA, Microbiology, 153, 3954, 10.1099/mic.0.2007/011049-0

Fairn, 2012, How nascent phagosomes mature to become phagolysosomes, Trends Immunol, 33, 397, 10.1016/j.it.2012.03.003

Frases, 2009, The elastic properties of the Cryptococcus neoformans capsule, Biophys J, 97, 937, 10.1016/j.bpj.2009.04.043

Geunes-Boyer, 2009, Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival, Infect Immun, 77, 2783, 10.1128/IAI.00088-09

Geunes-Boyer, 2012, Surfactant protein D facilitates Cryptococcus neoformans infection, Infect Immun, 80, 2444, 10.1128/IAI.05613-11

Goldman, 2000, Persistent Cryptococcus neoformans pulmonary infection in the rat is associated with intracellular parasitism, decreased inducible nitric oxide synthase expression, and altered antibody responsiveness to cryptococcal polysaccharide, Infect Immun, 68, 832, 10.1128/IAI.68.2.832-838.2000

Goldman, 2001, Serologic evidence for Cryptococcus neoformans infection in early childhood, Pediatrics, 107, E66, 10.1542/peds.107.5.e66

Heung, 2004, The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans, J Biol Chem, 279, 21144, 10.1074/jbc.M312995200

Huynh, 2007, Fusion, fission, and secretion during phagocytosis, Physiology (Bethesda), 22, 366, 10.1152/physiol.00028.2007

Hybiske, 2007, Mechanisms of host cell exit by the intracellular bacterium Chlamydia, Proc Natl Acad Sci USA, 104, 11430, 10.1073/pnas.0703218104

Johnston, 2010, The human fungal pathogen Cryptococcus neoformans escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation, PLoS Pathog, 6, e1001041, 10.1371/journal.ppat.1001041

Kozel, 1977, Non-encapsulated variant of Cryptococcus neoformans. II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide, Infect Immun, 16, 99, 10.1128/IAI.16.1.99-106.1977

Levitz, 1991, Binding of Cryptococcus neoformans by human cultured macrophages. Requirements for multiple complement receptors and actin, J Clin Invest, 87, 528, 10.1172/JCI115027

Levitz, 1991, Killing of Cryptococcus neoformans by human peripheral blood mononuclear cells stimulated in culture, J Infect Dis, 163, 1108, 10.1093/infdis/163.5.1108

Levitz, 1999, Cryptococcus neoformans resides in an acidic phagolysosome of human macrophages, Infect Immun, 67, 885, 10.1128/IAI.67.2.885-890.1999

Liu, 2008, Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans, Cell, 135, 174, 10.1016/j.cell.2008.07.046

Ma, 2006, Expulsion of live pathogenic yeast by macrophages, Curr Biol, 16, 2156, 10.1016/j.cub.2006.09.032

Ma, 2007, Direct cell-to-cell spread of a pathogenic yeast, BMC Immunol, 8, 15, 10.1186/1471-2172-8-15

Ma, 2009, The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation, Proc Natl Acad Sci USA, 106, 12980, 10.1073/pnas.0902963106

McQuiston, 2010, Role of host sphingosine kinase 1 in the lung response against Cryptococcosis, Infect Immun, 78, 2342, 10.1128/IAI.01140-09

Mukherjee, 1996, J774 murine macrophage-like cell interactions with Cryptococcus neoformans in the presence and absence of opsonins, J Infect Dis, 173, 1222, 10.1093/infdis/173.5.1222

Nakamura, 2007, Dectin-1 is not required for the host defense to Cryptococcus neoformans, Microbiol Immunol, 51, 1115, 10.1111/j.1348-0421.2007.tb04007.x

Nicola, 2011, Nonlytic exocytosis of Cryptococcus neoformans from macrophages occurs in vivo and is influenced by phagosomal pH, MBio, 2, 4, 10.1128/mBio.00167-11

Nicola, 2012, Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans, Infect Immun, 80, 3065, 10.1128/IAI.00358-12

Nordenfelt, 2011, Phagosome dynamics during phagocytosis by neutrophils, J Leukoc Biol, 90, 271, 10.1189/jlb.0810457

Noverr, 2003, Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production, Infect Immun, 71, 1538, 10.1128/IAI.71.3.1538-1547.2003

Okagaki, 2012, Titan cells confer protection from phagocytosis in Cryptococcus neoformans infections, Eukaryot Cell, 11, 820, 10.1128/EC.00121-12

Okagaki, 2010, Cryptococcal cell morphology affects host cell interactions and pathogenicity, PLoS Pathog, 6, e1000953, 10.1371/journal.ppat.1000953

Okagaki, 2011, Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli, Eukaryot Cell, 10, 1306, 10.1128/EC.05179-11

Onfelt, 2004, Cutting edge: membrane nanotubes connect immune cells, J Immunol, 173, 1511, 10.4049/jimmunol.173.3.1511

Park, 2009, Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS, AIDS, 23, 525, 10.1097/QAD.0b013e328322ffac

Qin, 2011, Functional analysis of host factors that mediate the intracellular lifestyle of Cryptococcus neoformans, PLoS Pathog, 7, e1002078, 10.1371/journal.ppat.1002078

Schaechter, 1957, Study on the growth of Rickettsiae. II. Morphologic observations of living Rickettsiae in tissue culture cells, Virology, 3, 160, 10.1016/0042-6822(57)90030-2

Shao, 2005, A dual role for TGF-beta1 in the control and persistence of fungal pneumonia, J Immunol, 175, 6757, 10.4049/jimmunol.175.10.6757

Shapiro, 2002, Immunoglobulin G monoclonal antibodies to Cryptococcus neoformans protect mice deficient in complement component C3, Infect Immun, 70, 2598, 10.1128/IAI.70.5.2598-2604.2002

Shea, 2006, The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system, Infect Immun, 74, 5977, 10.1128/IAI.00768-06

Siddiqui, 2005, IFN-gamma at the site of infection determines rate of clearance of infection in cryptococcal meningitis, J Immunol, 174, 1746, 10.4049/jimmunol.174.3.1746

Spira, 1996, Generation of biologically active anti-Cryptococcus neoformans IgG, IgE and IgA isotype switch variant antibodies by acridine orange mutagenesis, Clin Exp Immunol, 105, 436, 10.1046/j.1365-2249.1996.d01-786.x

Stano, 2009, App1: an antiphagocytic protein that binds to complement receptors 3 and 2, J Immunol, 182, 84, 10.4049/jimmunol.182.1.84

Steenbergen, 2003, The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans, Microbes Infect, 5, 667, 10.1016/S1286-4579(03)00092-3

Taborda, 2002, CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans, Immunity, 16, 791, 10.1016/S1074-7613(02)00328-X

Tucker, 2002, Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm, Proc Natl Acad Sci USA, 99, 3165, 10.1073/pnas.052702799

Velagapudi, 2009, Spores as infectious propagules of Cryptococcus neoformans, Infect Immun, 77, 4345, 10.1128/IAI.00542-09

Voelz, 2009, Cytokine signaling regulates the outcome of intracellular macrophage parasitism by Cryptococcus neoformans, Infect Immun, 77, 3450, 10.1128/IAI.00297-09

Voelz, 2010, Automated analysis of cryptococcal macrophage parasitism using GFP-tagged cryptococci, PLoS ONE, 5, e15968, 10.1371/journal.pone.0015968

West, 2011, TLR signalling augments macrophage bactericidal activity through mitochondrial ROS, Nature, 472, 476, 10.1038/nature09973

Wozniak, 2008, Cryptococcus neoformans enters the endolysosomal pathway of dendritic cells and is killed by lysosomal components, Infect Immun, 76, 4764, 10.1128/IAI.00660-08

Zaragoza, 2003, The efficacy of complement-mediated phagocytosis of Cryptococcus neoformans is dependent on the location of C3 in the polysaccharide capsule and involves both direct and indirect C3-mediated interactions, Eur J Immunol, 33, 1957, 10.1002/eji.200323848

Zaragoza, 2008, Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival, Cell Microbiol, 10, 2043, 10.1111/j.1462-5822.2008.01186.x

Zaragoza, 2010, Fungal cell gigantism during mammalian infection, PLoS Pathog, 6, e1000945, 10.1371/journal.ppat.1000945