Clostridium welchiifood poisoning

Cambridge University Press (CUP) - Tập 51 Số 1 - Trang 75-101 - 1953
Betty C. Hobbs1, Muriel E. Smith1, C. L. Oakley1, G. Harriet Warrack1, J. C. Cruickshank1
1The Food Hygiene Laboratory, Central Public Health Laboratory (Medical Research Council), Colindale, The Wellcome Research Laboratories (Biological Division), Beckenham, Kent, and The London School of Hygiene and Tropical Medicine

Tóm tắt

1. Outbreaks of mild food poisoning have been investigated in which heat-resistantCl. welchiiappeared to be the causative organism. The outbreaks were characterized by colic and diarrhoea without vomiting, commencing 8–20 hr. after ingestion of the contaminated food.2. The strains ofCl. welchiiconcerned are only feebly toxigenic, and apart from the heat-resistance of their spores, and some colonial characters, fit well intoCl. welchiiType A. The toxin production and the serology of the strains is uniform within an outbreak.3. Mild food poisoning similar to that seen in natural epidemics has been produced in volunteers by ingestion of cultures of heat-resistantCl. welchiiisolated from contaminated meat.4. Infection is almost invariably due to meat which has been boiled, steamed, braised, stewed or insufficiently roasted, allowed to cool slowly, and eaten the next day, either cold or reheated.5. Outbreaks of this kind should be prevented by cooking meat immediately before consumption; or, if this is impossible, by cooling the cooked meat rapidly and keeping it refrigerated until it is required for use.

Từ khóa


Tài liệu tham khảo

Hain, 1949, Brit. med. J., 1, 271

Wilsdon, 1932, 3rd Rep. Inst. Animal Path., Camb., 46

Mcclung, 1945, J. Bact., 50, 229, 10.1128/JB.50.2.229-231.1945

10.1093/infdis/48.5.468

Moore, 1948, Mon. Bull. Minist. Hlth Lab. Serv., 7, 136

Wilsdon, 1931, 2nd Rep. Inst. Animal Path., Camb., 53

Hauge, 1950, Nord. hyg. Tidskr., 31, 189

Bower, 1938, J. Immunol., 34, 185, 10.4049/jimmunol.34.3.185

Duncan, 1944, Mon. Bull. Minist. Hlth Lab. Serv., 3, 61

Simonds, 1915, Monogr. Rockefeller Inst., 5

10.1016/S0140-6736(01)78944-1

10.2307/4586416

10.1002/path.1700370107

10.1017/S002217240002800X

Klein, 1895, Zbl. Bakt. (1. Abt. Orig.), 18, 737

Knox, 1943, Med. Offr, 69, 21

Rodella, 1910, Wien. klin. Wschr., 23, 1683

Moore, 1948, Mon. Bull. Minist. Hlth Lab. Serv., 7, 241

Wild, 1898, Zbl. Bakt. (1. Abt. Orig.), 23, 913

10.1136/bmj.1.4597.267

10.1136/bmj.1.4607.724

10.1017/S0022172400015527

10.1002/path.1700570111

Dunham, 1897, Bull. Johns Hopk. Hosp., 8, 68

Von Hibler, 1906, Zbl. Bakt. (1. Abt. Ref.), 37, 545