+1 Proteins and aging

Vogel, 1998, Possible new cause of Alzheimer’s disease found, Science, 279, 174, 10.1126/science.279.5348.174 van Leeuwen, 1998, Frameshift mutations of β amyloid precursor protein and ubiquitin B in Alzheimer’s and Down patients, Science, 279, 242, 10.1126/science.279.5348.242 van den Hurk, 2001, Novel frameshift mutations near short simple repeats, J. Biol. Chem., 276, 11496, 10.1074/jbc.M011040200 Maquat, 2001, Quality control of mRNA function, Cell, 104, 173, 10.1016/S0092-8674(01)00202-1 van Leeuwen, 1998, Mutations in RNA: a first example of molecular misreading in Alzheimer’s disease, TINS, 21, 331 van Leeuwen, 2000, Molecular misreading in non-neuronal cells, FASEB J., 14, 1595, 10.1096/fj.14.11.1595 van Leeuwen, 1998, The magnocellular neurons of the hypothalamo-neurohypophyseal system display remarkable neuropeptidergic penotypes leading to novel insights in neuronal cell biology, Prog. Brain Res., 119, 115, 10.1016/S0079-6123(08)61565-4 Evans, 1994, Frameshift mutations at two hotspots in vasopressin transcripts in post-mitotic neurons, Proc. Natl. Acad. Sci. U.S.A., 91, 6059, 10.1073/pnas.91.13.6059 van Leeuwen, 2000, Molecular misreading: a new type of transcript mutation expressed during aging, Neurobiol. Aging, 21, 879, 10.1016/S0197-4580(00)00151-2 Fergusson, 2000, Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin B protein, Neurosci. Lett., 279, 69, 10.1016/S0304-3940(99)00917-9 Schwarz, 1999, The ubiquitin–proteasome pathway and pathogenesis of human diseases, Annu. Rev. Med., 50, 57, 10.1146/annurev.med.50.1.57 Lopez-Salon, 2001, The ubiquitin–proteasome cascade is required for mammalian long-term memory formation, Eur. J. Neurosci., 14, 1820, 10.1046/j.0953-816x.2001.01806.x de Vrij, 2001, Mutant ubiquitin expressed in Alzheimer’s disease causes neuronal death, FASEB J., 15, 2680, 10.1096/fj.01-0438com Lam, 2000, Inhibition of the ubiquitin proteasome system in Alzheimer’s disease, PNAS, 97, 9902, 10.1073/pnas.170173897 K. Lindsten, F.M.S. de Vrij, L.G.G.C. Verhoef, D.F. Fischer, F.W. van Leeuwen, E.M. Hol, M.G. Masucci, N.P. Dantuma, J. Cell Biol. 157 (2002) 417–427. Hersberger, 2001, A dinucleotide deletion in amyloid precursor protein (APP) mRNA associated with sporadic Alzheimer’s disease results in efficient secretion of truncated APP isoforms from neuroblastoma cell cultures, J. Neurochem., 76, 1308, 10.1046/j.1471-4159.2001.00122.x L.W. McPhaul, J. Wang, E.M. Hol, M.A.F. Sonnemans, N. Riley, V. Nguyen, Q.X. Yuan, F.W. van Leeuwen, S.W. French, Molecular misreading of the ubiquitin B gene and hepatic Mallory body formation, Gastroenterology, in press.