γH2AX assay in ex vivo irradiated tumour specimens: A novel method to determine tumour radiation sensitivity in patient-derived material

Radiotherapy and Oncology - Tập 116 - Trang 473-479 - 2015
Apostolos Menegakis1,2, Cläre von Neubeck3,4,5, Ala Yaromina6, Howard Thames7, Sandra Hering8, Joerg Hennenlotter9, Marcus Scharpf10, Susan Noell11, Mechthild Krause3,4,5,12, Daniel Zips1,2, Michael Baumann3,4,5,12
1Department of Radiation Oncology, Medical Faculty and University Hospital, Eberhard Karls University, Tübingen, Germany
2German Cancer Research Center (DKFZ), Heidelberg, Germany and German Cancer Consortium (DKTK), Partner Site Tübingen, Germany
3German Cancer Research Center (DKFZ), Heidelberg, Germany, and German Cancer Consortium (DKTK), partner site Dresden, Germany
4Department of Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany
5OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany
6Department of Radiation Oncology (MAASTRO), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, The Netherlands
7Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, USA
8Institute for Legal Medicine, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany
9Department of Urology, Medical Faculty and University Hospital, Eberhard Karls University Tübingen, Germany
10Department of Pathology, Medical Faculty and University Hospital, Eberhard Karls University Tübingen, Germany
11Department of Neurosurgery, Medical Faculty and University Hospital, Eberhard Karls University Tübingen, Germany
12Institute of Radiooncology, Helmholtz-Zentrum Dresden – Rossendorf, Germany

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