β-catenin interacts with and inhibits NF-κB in human colon and breast cancer

Cancer Cell - Tập 2 - Trang 323-334 - 2002
Jiong Deng1, Stephanie A Miller1, Hong-Ying Wang1, Weiya Xia2, Yong Wen1, Binhua P Zhou1, Yan Li3, Shiaw-Yih Lin1, Mien-Chie Hung1
1Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
2Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030 USA
3Department of Molecular and Cellular Oncology, The University of Texas, M. D. Anderson Cancer Center, Houston, TX 77030, USA

Tài liệu tham khảo

Baeuerle, 1988, Iκb, Science, 242, 540, 10.1126/science.3140380 Behrens, 1998, Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β, Science, 280, 596, 10.1126/science.280.5363.596 Ben-Ze'ev, 1998, Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer, Curr. Opin. Cell Biol., 10, 629, 10.1016/S0955-0674(98)80039-2 Bours, 2000, Nuclear factor-κB, cancer, and apoptosis, Biochem. Pharmacol., 60, 1085, 10.1016/S0006-2952(00)00391-9 Butler, 1998, Down-regulation of Fas gene expression in colon cancer is not a result of allelic loss or gene rearrangement, Br. J. Cancer, 77, 1454, 10.1038/bjc.1998.239 Chan, 1999, Activation-dependent transcriptional regulation of the human Fas promoter requires NF-κB p50-p65 recruitment, Mol. Cell. Biol., 19, 2098, 10.1128/MCB.19.3.2098 Chen, 2001, Wnt-1 signaling inhibits apoptosis by activating β-catenin/T cell factor-mediated transcription, J. Cell Biol., 152, 87, 10.1083/jcb.152.1.87 Cheng, 2001, Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells, Oncogene, 20, 7334, 10.1038/sj.onc.1204928 Crawford, 1999, The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors, Oncogene, 18, 2883, 10.1038/sj.onc.1202627 Damalas, 2001, Deregulated β-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation, EMBO J., 20, 4912, 10.1093/emboj/20.17.4912 Eischen, 2001, Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis, Mol. Cell. Biol., 21, 7653, 10.1128/MCB.21.22.7653-7662.2001 Gapuzan, 2002, Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-κB have a malignantly transformed phenotype, Oncogene, 21, 2484, 10.1038/sj.onc.1205333 Gerritsen, 1997, CREB-binding protein/p300 are transcriptional coactivators of p65, Proc. Natl. Acad. Sci. USA, 94, 2927, 10.1073/pnas.94.7.2927 Ghosh, 1998, NF-κB and Rel proteins, Annu. Rev. Immunol., 16, 225, 10.1146/annurev.immunol.16.1.225 Gilmore, 1996, Rel/NF-κB/IκB proteins and cancer, Oncogene, 13, 1367 Gumbiner, 1995, Signal transduction of β-catenin, Curr. Opin. Cell Biol., 7, 634, 10.1016/0955-0674(95)80104-9 He, 1998, Identification of c-MYC as a target of the APC pathway, Science, 281, 1509, 10.1126/science.281.5382.1509 Hecht, 2000, The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates, EMBO J., 19, 1839, 10.1093/emboj/19.8.1839 Hoeflich, 2000, Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation, Nature, 406, 86, 10.1038/35017574 Hsu, 1995, Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis, Oncogene, 11, 175 Hunt, 1997, Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53, Cancer Res., 57, 4722 Kikuchi, 1999, Roles of Axin in the Wnt signalling pathway, Cell. Signal., 11, 777, 10.1016/S0898-6568(99)00054-6 Kim, 2000, Overexpression of β-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators, Mol. Biol. Cell, 11, 3509, 10.1091/mbc.11.10.3509 Kinzler, 1996, Lessons from hereditary colorectal cancer, Cell, 87, 159, 10.1016/S0092-8674(00)81333-1 Korinek, 1997, Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC−/− colon carcinoma, Science, 275, 1784, 10.1126/science.275.5307.1784 Lin, 2000, β-catenin, a novel prognostic marker for breast cancer, Proc. Natl. Acad. Sci. USA, 97, 4262, 10.1073/pnas.060025397 Liu, 1996, Dissection of TNF receptor 1 effector functions, Cell, 87, 565, 10.1016/S0092-8674(00)81375-6 Macleod, 1999, pRb and E2f-1 in mouse development and tumorigenesis, Curr. Opin. Genet. Dev., 9, 31, 10.1016/S0959-437X(99)80005-7 Miyagishi, 2000, Regulation of Lef-mediated transcription and p53-dependent pathway by associating β-catenin with CBP/p300, J. Biol. Chem., 275, 35170, 10.1074/jbc.C000258200 Morin, 1997, Activation of β-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC, Science, 275, 1787, 10.1126/science.275.5307.1787 O'Connell, 2000, Altered mechanisms of apoptosis in colon cancer, Ann. N Y Acad. Sci., 910, 178, 10.1111/j.1749-6632.2000.tb06708.x Orford, 1997, Serine phosphorylation-regulated ubiquitination and degradation of β-catenin, J. Biol. Chem., 272, 24735, 10.1074/jbc.272.40.24735 Ouaaz, 1999, A critical role for the RelA subunit of nuclear factor κB in regulation of multiple immune-response genes and in Fas-induced cell death, J. Exp. Med., 189, 999, 10.1084/jem.189.6.999 Perkins, 1997, Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator, Science, 275, 523, 10.1126/science.275.5299.523 Polakis, 1999, The oncogenic activation of β-catenin, Curr. Opin. Genet. Dev., 9, 15, 10.1016/S0959-437X(99)80003-3 Polakis, 2000, Wnt signaling and cancer, Genes Dev., 14, 1837, 10.1101/gad.14.15.1837 Romagnolo, 1999, Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated β-catenin, Cancer Res., 59, 3875 Ryan, 2000, Role of NF-κB in p53-mediated programmed cell death, Nature, 404, 892, 10.1038/35009130 Sasaki, 2000, Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ, Nature, 406, 897, 10.1038/35022585 Schmid, 2000, Dynamics of NFκB and IκBα studied with green fluorescent protein (GFP) fusion proteins. Investigation of GFP-p65 binding to DNa by fluorescence resonance energy transfer, J. Biol. Chem., 275, 17035, 10.1074/jbc.M000291200 Sun, 2000, Regulation of β-catenin transformation by the p300 transcriptional coactivator, Proc. Natl. Acad. Sci. USA, 97, 12613, 10.1073/pnas.220158597 Tetsu, 1999, β-catenin regulates expression of cyclin D1 in colon carcinoma cells, Nature, 398, 422, 10.1038/18884 Trent, 1996, Ras signaling in tumor necrosis factor-induced apoptosis, EMBO J., 15, 4497, 10.1002/j.1460-2075.1996.tb00827.x von Reyher, 1998, Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis, Cancer Res., 58, 526 Wang, 1996, TNF- and cancer therapy-induced apoptosis, Science, 274, 784, 10.1126/science.274.5288.784 Wang, 1998, NF-κB antiapoptosis, Science, 281, 1680, 10.1126/science.281.5383.1680 Wang, 1999, The nuclear factor-κB RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells, Clin. Cancer Res., 5, 119 Willert, 1998, β-catenin, Curr. Opin. Genet. Dev., 8, 95, 10.1016/S0959-437X(98)80068-3 Wong, 1998, Effects of forced expression of an NH2-terminal truncated β-catenin on mouse intestinal epithelial homeostasis, J. Cell Biol., 141, 765, 10.1083/jcb.141.3.765 Yang, 2002, Linking β-catenin to androgen-signaling pathway, J. Biol. Chem., 277, 11336, 10.1074/jbc.M111962200 Zheng, 2001, NF-κB RelA (p65) is essential for TNF-α-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death, J. Immunol., 166, 4949, 10.4049/jimmunol.166.8.4949 Zhou, 2000, HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-κB pathway, J. Biol. Chem., 275, 8027, 10.1074/jbc.275.11.8027