β-Catenin Mutations Are Associated with a Subset of Low-Stage Hepatocellular Carcinoma Negative for Hepatitis B Virus and with Favorable Prognosis
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Jou, 1995, Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex, Proc Natl Acad Sci USA, 92, 5067, 10.1073/pnas.92.11.5067
Larabell, 1997, Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in β-catenin that are modulated by the Wnt signaling pathway, J Cell Biol, 136, 1123, 10.1083/jcb.136.5.1123
Funayama, 1995, Embryonic axis induction by the armadillo repeat domain of β-catenin: evidence for intracellular signaling, J Cell Biol, 128, 959, 10.1083/jcb.128.5.959
Yost, 1996, The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3, Genes Dev, 10, 1443, 10.1101/gad.10.12.1443
Morin, 1997, Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC, Science, 275, 1787, 10.1126/science.275.5307.1787
Miller, 1997, Analysis of the signaling activities of localization mutants of β-catenin during axis specification in Xenopus, J Cell Biol, 139, 229, 10.1083/jcb.139.1.229
Behrens, 1996, Functional interaction of β-catenin with the transcription factor LEF-1, Nature, 382, 638, 10.1038/382638a0
Korinek, 1997, Constitutive transcriptional activation by a β-catenin-Tcf complex in APC−/− colon carcinoma, Science, 275, 1784, 10.1126/science.275.5307.1784
Rubinfeld, 1993, Association of the APC gene product with β-catenin, Science, 262, 1731, 10.1126/science.8259518
Su, 1993, Association of the APC tumor suppressor protein with catenins, Science, 262, 1734, 10.1126/science.8259519
Orford, 1997, Serine phosphorylation-regulated ubiquitination and degradation of β-catenin, J Biol Chem, 272, 24735, 10.1074/jbc.272.40.24735
Sparks, 1997, Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer, Cancer Res, 58, 1130
Rubinfeld, 1997, Stabilization of β-catenin by genetic defects in melanoma cell lines, Science, 275, 1790, 10.1126/science.275.5307.1790
Fukuchi, 1998, β-Catenin mutation in carcinoma of the uterine endometrium, Cancer Res, 58, 3526
Voeller, 1998, β-Catenin mutations in human prostate cancer, Cancer Res, 58, 2520
Dashwood, 1998, High frequency of β-catenin (Ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat, Cancer Res, 58, 1127
Takahashi, 1998, β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced at colon tumors, Cancer Res, 58, 42
Chan, 1999, A common human skin tumour is caused by activating mutations in β-catenin, Nat Genet, 21, 410, 10.1038/7747
Samowitz, 1999, β-Catenin mutations are frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas, Cancer Res, 59, 1442
Hsu, 1988, Tumor invasiveness and prognosis in resected hepatocellular carcinoma: clinical and pathogenetic implications, Cancer, 61, 2095, 10.1002/1097-0142(19880515)61:10<2095::AID-CNCR2820611027>3.0.CO;2-H
Hsu, 1993, Expression of p53 gene in 184 unifocal hepatocellular carcinomas: association with tumor growth and invasiveness, Cancer Res, 53, 4691
Hsu, 1994, Mutations of p53 gene in hepatocellular carcinoma (HCC) correlate with tumor progression and patient prognosis: a study of 138 patients with unifocal HCC, Int J Oncol, 4, 1341
de La Coste, 1998, Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas, Proc Natl Acad Sci USA, 95, 8847, 10.1073/pnas.95.15.8847
Miyoshi, 1998, Activation of the β-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3, Cancer Res, 58, 2524
Ogawa, 1999, β-Catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice, Cancer Res, 59, 1830
Hsu, 1991, Clonality and clonal evolution of hepatocellular carcinoma with multiple nodules, Hepatology, 13, 923, 10.1002/hep.1840130520
Peng, 1993, Expression and hypomethylation of alpha-fetoprotein gene in unicentric and multicentric human hepatocellular carcinomas, Hepatology, 17, 35, 10.1002/hep.1840170108
Lee, 1986, Surgical treatment of 109 patients with symptomatic and asymptomatic hepatocellular carcinoma, Surgery, 99, 481
Franco, 1990, Resection of hepatocellular carcinomas: results in 72 European patients with cirrhosis, Gastroenterology, 98, 733, 10.1016/0016-5085(90)90296-D
Peng, 1998, Association of downregulation of cyclin D1 and of overexpression of cyclin E with p53 mutation, high tumor grade and poor prognosis in hepatocellular carcinoma, J Hepatol, 29, 281, 10.1016/S0168-8278(98)80014-7
Nollet, 1996, Genomic organization of the human β-catenin gene (CTNNB1), Genomics, 32, 413, 10.1006/geno.1996.0136
Koch, 1999, Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the β-catenin gene, Cancer Res, 59, 269
Huang, 1999, β-Catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection, Am J Pathol, 155, 1795, 10.1016/S0002-9440(10)65496-X
Tanizaki, 1997, Comparison of clinical features and survival in patients with hepatitis B and C virus-related hepatocellular carcinoma, Jpn J Clin Oncol, 27, 67, 10.1093/jjco/27.2.67
Stroffolini, 1998, Characteristics of hepatocellular carcinoma in Italy, J Hepatol, 29, 944, 10.1016/S0168-8278(98)80122-0
Legoix, 1999, Beta-catenin in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity, Oncogene, 18, 4044, 10.1038/sj.onc.1202800
Tsujiuchi, 1999, Different frequencies and patterns of β-catenin mutations in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient l-amino acid-defined diet in rats, Cancer Res, 59, 3904
Jeng, 2000, Somatic mutations of β-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma, Cancer Lett, 152, 45, 10.1016/S0304-3835(99)00433-4
Peifer, 1994, Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and Zeste-white 3 kinase, Dev Biol, 166, 543, 10.1006/dbio.1994.1336
Palacios, 1998, Mutations in the β-catenin (CTNNB1) in endometrioid ovarian carcinomas, Cancer Res, 58, 1344
Gamallo, 1999, β-Catenin expression pattern in stage I and II ovarian carcinomas: relationship with β-catenin mutations, clinicopathological features, and clinical outcome, Am J Pathol, 155, 527, 10.1016/S0002-9440(10)65148-6
Shibata, 1996, Dominant-negative inhibition of the association between β-catenin and c-erbB-2 by N-terminally deleted β-catenin suppresses the invasion and metastasis of cancer cells, Oncogene, 13, 883