α-adrenoceptor-mediated positive inotropic effect of phenylephrine in isolated human ventricular myocardium

European Journal of Pharmacology - Tập 99 Số 4 - Trang 345-347 - 1984
Reinhard Brückner1, Wilfried Meyer1, Giuseppe Licata1, Wilhelm Schmitz1, Hasso Scholz1
1Abteilung Allgemeine Pharmakologie, Universitäts-Krankenhaus Eppendorf, Universität Hamburg, Martinistrasse 52, D-2000 Hamburg 20, F.R.G.

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Tài liệu tham khảo

Benfey, 1980, Cardiac α-adrenoceptors, Can. J. Physiol. Pharmacol., 58, 1145, 10.1139/y80-174

Meinertz, 1976, Possible role of cyclic AMP in the relaxation process of mammalian heart: Effects of dibutyryl cyclic AMP and theophylline on potassium contractures in cat papillary muscles, Naunyn Schmiedeb. Arch. Pharmacol., 293, 129, 10.1007/BF00499217

Scholz, 1980, Effects of beta- and alpha-adrenoceptor activators and adrenergic transmitter releasing agents on the mechanical activity of the heart, Vol. 54/I, 651

Scholz, 1983, Pharmacological actions of various inotropic agents, European Heart J., 4, 651

Schümann, 1980, Are there α-adrenoceptors in the mammalian heart?, Trends Pharmacol. Sci., 1, 195, 10.1016/0165-6147(79)90069-5

Schümann, 1978, Demonstration in human atrial preparations of α-adrenoceptors mediating positive inotropic effects, Naunyn-Schmiedeb. Arch. Pharmacol., 302, 333, 10.1007/BF00508304

Shibata, 1980, The regional and species differences on the activation of myocardial alpha-adrenoceptors by phenylephrine and methoxamine, Gen. Pharmacol., 11, 173, 10.1016/0306-3623(80)90057-9

Tsien, 1977, Cyclic AMP and contractile activity in heart, Adv. Cycl. Nucl. Res., 8, 363