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Pneumologie 77:269–302. https:\u002F\u002Fdoi.org\u002F10.1055\u002Fa-2017-8971\nDoyle TJ, Dellaripa PF (2017) Lung manifestations in the rheumatic diseases. Chest 152:1283–1295\nFischer A, Strek ME, Cottin V, Dellaripa PF, Bernstein EJ, Brown KK, Danoff SK, Distler O, Hirani N, Jones KD, Khanna D, Lee JS, Lynch DA, Maher TM, Millar AB, Raghu G, Silver RM, Steen VD, Volkmann ER, Mullan RH, O’Dwyer DN, Donnelly SC (2019) Proceedings of the American college of rheumatology\u002Fassociation of physicians of Great Britain and Ireland connective tissue disease-associated interstitial lung disease summit: a multidisciplinary approach to address challenges and opportunities. Arthritis Rheumatol 71:182–195\nWijsenbeek M, Cottin V (2020) Spectrum of fibrotic lung diseases. N Engl J Med 383:958–968\nBehr J, Prasse A, Wirtz H, Koschel D, Pittrow D, Held M, Klotsche J, Andreas S, Claussen M, Grohe C, Wilkens H, Hagmeyer L, Skowasch D, Meyer JF, Kirschner J, Glaser S, Kahn N, Welte T, Neurohr C, Schwaiblmair M, Bahmer T, Oqueka T, Frankenberger M, Kreuter M (2020) Survival and course of lung function in the presence or absence of antifibrotic treatment in patients with idiopathic pulmonary fibrosis: long-term results of the INSIGHTS-IPF registry. Eur Respir J 56:1902279. https:\u002F\u002Fdoi.org\u002F10.1183\u002F13993003.02279-2019\nBlanc PD, Annesi-Maesano I, Balmes JR, Cummings KJ, Fishwick D, Miedinger D, Murgia N, Naidoo RN, Reynolds CJ, Sigsgaard T, Toren K, Vinnikov D, Redlich CA (2019) The occupational burden of nonmalignant respiratory diseases. An official American thoracic society and European respiratory society statement. Am J Respir Crit Care Med 199:1312–1334\nSchegerer A, Loose R, Heuser LJ, Brix G (2019) Diagnostic reference levels for diagnostic and interventional X‑ray procedures in Germany: update and handling. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. Thieme, Stuttgart, S 739–751\nTravis WD, Costabel U, Hansell DM, King TE Jr, Lynch DA, Nicholson AG, Ryerson CJ, Ryu JH, Selman M, Wells AU (2013) An official American thoracic society\u002FEuropean respiratory society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 188:733–748\nLänger F, Stark H, Braubach P, Ackermann M, Hussein K, Teiken K, Maegel L, Kuehnel M, Jonigk D (2018) Injury patterns in interstitial lung diseases. Pathologe 39:262–271\nBehr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geißler K, Gläser S, Handzhhiev S, Jonigk D (2020) S2K-Leitlinie zur Diagnostik der idiopathischen Lungenfibrose. Pneumologie 74:263–293\nFurini F, Carnevale A, Casoni GL, Guerrini G, Cavagna L, Govoni M, Sciré CA (2019) The role of the multidisciplinary evaluation of interstitial lung diseases: systematic literature review of the current evidence and future perspectives. Front Med 6:246\nValeyre D (2011) Towards a better diagnosis of idiopathic pulmonary fibrosis. Eur Respir Rev 20:108–113\nSpagnolo P, Tonelli R, Cocconcelli E, Stefani A, Richeldi L (2012) Idiopathic pulmonary fibrosis: diagnostic pitfalls and therapeutic challenges. Multidiscip Respir Med 7:42\nNathan SD, Shlobin OA, Weir N, Ahmad S, Kaldjob JM, Battle E, Sheridan MJ, du Bois RM (2011) Long-term course and prognosis of idiopathic pulmonary fibrosis in the new millennium. Chest 140:221–229\nFlaherty KR, King TE Jr, Raghu G, Lynch JP III, Colby TV, Travis WD, Gross BH, Kazerooni EA, Toews GB, Long Q (2004) Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis? Am J Respir Crit Care Med 170:904–910\nNicholson A, Addis B, Bharucha H, Clelland C, Corrin B, Gibbs A, Hasleton P, Kerr K, Ibrahim N, Stewart S (2004) Inter-observer variation between pathologists in diffuse parenchymal lung disease. Thorax 59:500–505\nRaghu G, Amatto VC, Behr J, Stowasser S (2015) Comorbidities in idiopathic pulmonary fibrosis patients: a systematic literature review. Eur Respir J 46:1113–1130",{"EN":194},"Die Diagnosestellung interstitieller Lungenerkrankungen (ILD) ist anspruchsvoll und erfordert eine enge Zusammenarbeit verschiedener medizinischer Fachdisziplinen. Wie erfolgt die State-of-the-Art-Diagnostik bei Verdacht auf das Vorliegen einer ILD? 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Data of a German multicenter study; citation_author=M Raulf, M Joest, I Sander; citation_volume=28; citation_publication_date=2019; citation_pages=52-63; citation_doi=10.1007\u002Fs15007-019-1917-7; citation_id=CR23\ncitation_journal_title=Eur Respir J; citation_title=Development and validation of a radiological diagnosis model for hypersensitivity pneumonitis; citation_author=ML Salisbury, BH Gross, A Chugtai; citation_volume=52; citation_publication_date=2018; citation_pages=1800443; citation_doi=10.1183\u002F13993003.00443-2018; citation_id=CR24\ncitation_journal_title=Am J Respir Crit Care Med; citation_title=Diagnosis and treatment of fibrotic hypersensitivity pneumonia: where we stand and where we need to go; citation_author=ML Salisbury, JL Myers, EA Belloli; citation_volume=196; citation_publication_date=2017; citation_pages=690-699; citation_doi=10.1164\u002Frccm.201608-1675PP; citation_id=CR25\ncitation_journal_title=Pneumologie; citation_title=Empfehlungen zur Diagnostik der exogen-allergischen Alveolitis; citation_author=J Sennekamp, D Müller-Wening, M Amthor; citation_volume=61; citation_publication_date=2007; citation_pages=52-56; citation_doi=10.1055\u002Fs-2006-944326; citation_id=CR26\ncitation_journal_title=Am J Respir Crit Care Med; citation_title=New guideline diagnosis of fibrotic hypersensitivity pneumonitis in idiopathic pulmonary fibrosis; citation_author=R Takei, Y Yamano, K Kataoke; citation_volume=204; citation_publication_date=2021; citation_pages=603-605; citation_doi=10.1164\u002Frccm.202102-0407LE; citation_id=CR27\ncitation_journal_title=Ann Am Thorac Soc; citation_title=The amount of avian antigen in household dust predicts the prognosis of chronic bird-related hypersensitivity pneumonitis; citation_author=T Tsutsui, Y Miyazaki, J Kuramochi; citation_volume=12; citation_publication_date=2015; citation_pages=1013-1021; citation_doi=10.1513\u002FAnnalsATS.201412-569OC; citation_id=CR28\ncitation_journal_title=Am J Respir Crit Care Med; citation_title=Hypersensitivity pneumonitis: perspectives in diagnosis and management; citation_author=M Vasakova, F Morell, S Walsh; citation_volume=196; citation_publication_date=2017; citation_pages=680-689; citation_doi=10.1164\u002Frccm.201611-2201PP; citation_id=CR29\ncitation_journal_title=Eur Respir J; citation_title=Predictive value of BAL cell differentials in the diagnosis of interstitial lung disease; citation_author=L Welker, U Jörres, U Costabel; citation_volume=24; citation_publication_date=2004; citation_pages=1000-1006; citation_doi=10.1183\u002F09031936.04.00101303; citation_id=CR30\ncitation_journal_title=J Allergy Clin Immunol; citation_title=Chronic hypersensitivity pneumonitis in Japan: a nationwide epidemiologic survey; citation_author=Y Yoshizawa, Y Ohtani, H Hayakawa; citation_volume=103; citation_publication_date=1999; citation_pages=315-320; citation_doi=10.1016\u002FS0091-6749(99)70507-5; citation_id=CR31",{"DE":390},"In den letzten Jahren wurden 2 internationale Leitlinien für die Diagnostik der exogen-allergischen Alveolitis (EAA) publiziert. Es erfolgt die Bewertung der beiden neuen internationalen EAA-Leitlinien bezüglich Stärken und Schwächen insbesondere im Hinblick auf Praktikabilität im klinischen Alltag und auch unter Berücksichtigung arbeitsmedizinischer Aspekte im Berufskrankheitenverfahren. Es erfolgte eine Analyse der beiden internationalen EAA-Leitlinien und deren Empfehlungen mit anschließender Diskussion. In beiden Leitlinien wurden wichtige diagnostische Fragestellungen nach dem GRADE-System mit entsprechender Graduierung einer Empfehlung (schwach bis stark) beantwortet. Eine in beiden Publikationen empfohlene alleinige Unterteilung der EAA in nichtfibrotischen und fibrotischen Verlauf hat zwar Vorteile für die Prognosebewertung und Therapiewahl, aber dadurch wird nicht adäquat zwischen akuten und chronisch nichtfibrotischen Verläufen unterschieden. Die Differenzierung der EAA-Diagnose in mehrere Konfidenzstufen erscheint insbesondere für die Patientenkommunikation oder auch im Berufskrankheitenrecht problematisch. Die Notwendigkeit einer invasiven Diagnostik mittels BAL (bronchoalveoläre Lavage) bzw. BAL und Lungenbiopsie für die Diagnose einer EAA mit hoher Konfidenz bzw. definitive Diagnose einer EAA ist v. a. bei akuten nichtfibrotischen Verläufen nicht gerechtfertigt. Beide internationale Leitlinien zur Diagnostik der EAA geben einen sehr guten Überblick über die vorhandene Evidenz einzelner diagnostischer Verfahren. Eine an das deutsche Gesundheitssystem angepasste deutsche Leitlinienmodifikation ist notwendig.",{"DE":392},"Neue internationale Diagnoseleitlinien zur Diagnose der exogen-allergischen Alveolitis",{"VOID":394},"10.1007\u002Fs10405-023-00526-9","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs10405-023-00526-9","https:\u002F\u002Flink.springer.com\u002Fcontent\u002Fpdf\u002F10.1007\u002Fs10405-023-00526-9.pdf",[398],{"id":399,"sortIndex":21,"researcher":20,"roles":400,"affiliations":401,"properties":430},"88f980f9-3deb-4df4-bc31-f1b9af2c5e8c",[204],[402,412,420],{"id":403,"sortIndex":94,"affiliation":404,"properties":411},"16f22a53-9c97-4ee0-8483-613b2786801a",{"id":405,"createTime":406,"updateTime":406,"relativeEntities":407,"slug":20,"properties":408,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"d9c8377f-e2eb-4002-acbc-f3ddf9a23dd7","2024-01-28T09:00:58.885+00:00",[],{"title":409},{"VI":410}," Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Dresden, Deutschland",{},{"id":20,"sortIndex":21,"affiliation":413,"properties":20},{"id":414,"createTime":415,"updateTime":415,"relativeEntities":416,"slug":20,"properties":417,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"e64f5d92-e24c-43f5-8362-5c23cb78bed5","2024-01-28T09:00:58.872+00:00",[],{"title":418},{"VI":419},"Abteilung Innere Medizin und Pneumologie, Fachkrankenhaus Coswig, Lungenzentrum, Coswig, Deutschland",{"id":421,"sortIndex":96,"affiliation":422,"properties":429},"2b03a3d9-a546-4975-9d3e-b8993fba6479",{"id":423,"createTime":424,"updateTime":424,"relativeEntities":425,"slug":20,"properties":426,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"9faf9708-b945-4e80-96a7-27d4a9d3c3d0","2024-01-28T09:00:58.878+00:00",[],{"title":427},{"VI":428},"Ostdeutsches Lungenzentrum, Coswig-Dresden, Deutschland",{},{"title":431},{"VI":432},"Koschel, Dirk",{"url":395,"publisher":434,"properties":461},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":435,"slug":10,"properties":436,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":440,"manageAffiliations":441,"indexDatabases":442,"url":91,"thumbnailPath":20,"statistic":456,"gsStatistic":20,"type":99,"analyzePriority":20},[],{"issn":437,"eissn":438,"title":439},{"VOID":13},{"VOID":15},{"EN":17},[],[],[443,450],{"id":55,"indexDatabase":444,"url":70,"indexYears":20,"academicFieldIds":449,"indexDatabaseRanking":20},{"id":57,"createTime":58,"updateTime":59,"relativeEntities":445,"label":446,"description":447,"key":66,"publicationTags":448,"standard":20},[],{"EN":62,"VI":62},{"VI":64,"EN":65},[68,69],[72,73],{"id":75,"indexDatabase":451,"url":88,"indexYears":89,"academicFieldIds":20,"indexDatabaseRanking":90},{"id":77,"createTime":78,"updateTime":79,"relativeEntities":452,"label":453,"description":454,"key":85,"publicationTags":455,"standard":20},[],{"EN":82,"VI":82},{"EN":82,"VI":84},[87],{"impactFactor":21,"impactFactorByYear":457,"i10Index":21,"i10IndexLast5Year":21,"totalPublication":94,"totalPublicationByYear":458,"totalCitation":21,"totalCitationByYear":459,"totalCitationPerPublication":21,"totalCitationPerPublicationByYear":460,"hindexLast5Year":21,"hindex":21},{},{"2022":96,"2023":96},{},{},{"volume":462,"pages":463,"issue":465},{"VOID":375},{"VOID":464},"313-324",{"VOID":466},"6","2023-11-01",{"id":469,"createTime":470,"updateTime":471,"relativeEntities":472,"slug":473,"properties":474,"entityType":118,"verifyStatus":119,"verifyTime":471,"verifyNote":120,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":483,"fullTextUrl":20,"authors":484,"publicationType":143,"publisherRelationship":674,"citationCount":20,"citationInfo":20,"publishDate":705,"publishYear":706,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":20,"isForceReanalyzing":183},"21eac6af-5aea-4ba5-b2d2-67465cff226d","2024-01-19T03:35:31.250+00:00","2025-02-22T22:21:42.524+00:00",[],"R%C3%B6ntgenbefunde-bei-diffusen-parenchymat%C3%B6sen-Lungenerkrankungen",{"references":475,"abstract":477,"title":479,"doi":481},{"VOID":476},"Lynch J III, Weigt S, Fishbein M (2007) Diffuse parenchymal lung disease. 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Radiologe 56(10):866–873\nNachiappan AC et al (2017) Pulmonary tuberculosis: role of radiology in diagnosis and management. Radiographics 37(1):52–72\nElicker BM, Webb WR (2013) Fundamentals of high-resolution lung CT: common findings, common patterns, common diseases, and differential diagnosis. Wolters Kluwer Health, Lippincott Williams & Wilkins, Philadelphia, S 204–206\nVoegeli E (2009) Praktische Thoraxradiologie Bd. 5. Huber, Bern, S 128\nMüller-Mang C et al (2007) Idiopathic interstitial pneumonias: from classification to diagnostic work-up. Radiologe 47(5):384–392\nRaghu G et al (2018) Diagnosis of idiopathic pulmonary fibrosis. An official ATS\u002FERS\u002FJRS\u002FALAT clinical practice guideline. Am J Respir Crit Care Med 198(5):e44–e68\nBaur X, Fischer A, Budnik LT (2015) Spotlight on the diagnosis of extrinsic allergic alveolitis (hypersensitivity pneumonitis). J Occup Med Toxicol 10:15\nMueller-Mang C et al (2007) What every radiologist should know about idiopathic interstitial pneumonias. Radiographics 27(3):595–615\nKatzenstein AL, Fiorelli RF (1994) Nonspecific interstitial pneumonia\u002Ffibrosis. Histologic features and clinical significance. Am J Surg Pathol 18(2):136–147\nJegal Y et al (2005) Physiology is a stronger predictor of survival than pathology in fibrotic interstitial pneumonia. Am J Respir Crit Care Med 171(6):639–644\nBaque-Juston M et al (2014) Organizing pneumonia: What is it? A conceptual approach and pictorial review. Diagn Interv Imaging 95(9):771–777\nReddy TL et al (2012) Pleuroparenchymal fibroelastosis: a spectrum of histopathological and imaging phenotypes. Eur Respir J 40(2):377–385\nGaneshan D et al (2018) Sarcoidosis from head to toe: what the radiologist needs to know. Radiographics 38(4):1180–1200\nScadding JG (1961) Prognosis of intrathoracic sarcoidosis in England. A review of 136 cases after five years’ observation. Br Med J 2(5261):1165–1172\nTazi A (2006) Adult pulmonary Langerhans’ cell histiocytosis. Eur Respir J 27(6):1272–1285\nSchaefer-Prokop C et al (2001) High-resolution CT of diffuse interstitial lung disease: key findings in common disorders. Eur Radiol 11(3):373–392\nCollins J (2008) Chest radiology: the essentials. Wolters Kluwer, Lippincott Williams & Wilkins, Philadelphia",{"EN":478},"Diffuse parenchymatöse Lungenerkrankungen umfassen eine heterogene Krankheitsgruppe des Lungenparenchyms, der Alveolarräume, der Gefäße sowie Atemwege, welche durch diverse Pathomechanismen, wie Entzündung sowie fibrotische Veränderungen, ausgelöst werden können. Da sich die Therapieansätze sowie Prognosen zwischen den Erkrankungen wesentlich unterscheiden, ist die korrekte Diagnosestellung von grundlegender Bedeutung. In der klinischen Routine spielt neben der Anamnese, der Klinik, den Laborbefunden und der Bronchoskopie die Bildgebung eine zentrale Rolle in der Diagnosefindung. Die Diagnose diffuser parenchymatöser Lungenerkrankungen stellt eine enorme Herausforderung sowohl für Kliniker, Radiologen als auch Pathologen dar und sollte daher bevorzugt im multidisziplinären Rahmen erfolgen. Da sich die Patienten häufig mit einer unspezifischen, respiratorischen Symptomatik präsentieren, ist das Thorax-Röntgen die erste bildgebende Methode, welche eingesetzt wird. Bereits hier sind oft die verschiedenen Muster diffuser parenchymatöser Lungenerkrankungen (z. B. Milchglasverdichtungen und Konsolidierungen), deren Verteilung (z. B. kranial-kaudal) sowie zusätzliche Befunde, wie mediastinale Lymphadenopathie, bereits erkennbar. Der bildgebende Referenzstandard und somit integraler Bestandteil bei der Beurteilung einer diffusen parenchymatösen Lungenerkrankung ist jedoch die hochauflösende („high resolution“, HR) Computertomographie (CT) des Thorax. In manchen Fällen ist das Muster der HR-CT pathognomonisch, in anderen jedoch unspezifisch für eine Erkrankung, sodass weitere diagnostische Schritte nötig sind.",{"EN":480},"Röntgenbefunde bei diffusen parenchymatösen Lungenerkrankungen",{"VOID":482},"10.1007\u002Fs10405-024-00541-4","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs10405-024-00541-4",[485,511,540,559,578,598,617,636,655],{"id":486,"sortIndex":487,"researcher":20,"roles":488,"affiliations":489,"properties":508},"4ce28a40-bcdb-4bc5-9dd5-3f9b3d7c3bf7",7,[204],[490,500],{"id":491,"sortIndex":96,"affiliation":492,"properties":499},"ba9700c6-a1ec-4a7f-bcf4-128fb7b8ccb6",{"id":493,"createTime":494,"updateTime":494,"relativeEntities":495,"slug":20,"properties":496,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"4fc715c4-1352-4777-9625-ebe2b59fe24f","2024-02-13T09:35:33.467+00:00",[],{"title":497},{"VI":498},"Universitätsklinik für Radiologie und Nuklearmedizin, Medizinische Universität Wien, Wien, Österreich",{},{"id":20,"sortIndex":21,"affiliation":501,"properties":20},{"id":502,"createTime":503,"updateTime":503,"relativeEntities":504,"slug":20,"properties":505,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"c796a88b-9817-4d01-90d9-846c7784780e","2024-02-11T16:58:19.079+00:00",[],{"title":506},{"VI":507},"Department of Biomedical Imaging and Image-guided Therapy, Medizinische Universität Wien, Wien, Österreich",{"title":509},{"VI":510},"Sebastian Röhrich",{"id":512,"sortIndex":21,"researcher":20,"roles":513,"affiliations":514,"properties":537},"684117c4-dbc2-4e0e-a35a-61f9d0609e7f",[204],[515,525,532],{"id":516,"sortIndex":94,"affiliation":517,"properties":524},"e725aecf-1ff5-4a2e-b81b-febe54e8de01",{"id":518,"createTime":519,"updateTime":519,"relativeEntities":520,"slug":20,"properties":521,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"b88435c4-e70b-4738-a168-a53ae36c9c41","2024-02-11T16:58:19.028+00:00",[],{"title":522},{"VI":523},"Department of Radiology, University of Massachusetts Chan Medical School, Worcester, USA",{},{"id":526,"sortIndex":96,"affiliation":527,"properties":531},"dc8d9097-9ee6-455f-8d87-0d1001a0889d",{"id":493,"createTime":494,"updateTime":494,"relativeEntities":528,"slug":20,"properties":529,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":530},{"VI":498},{},{"id":20,"sortIndex":21,"affiliation":533,"properties":20},{"id":502,"createTime":503,"updateTime":503,"relativeEntities":534,"slug":20,"properties":535,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},[],{"title":536},{"VI":507},{"title":538},{"VI":539},"Daria 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N Engl J Med. https:\u002F\u002Fdoi.org\u002F10.1056\u002FNEJMoa1809697\nAupérin A, Le Péchoux C, Rolland E et al (2010) Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer. J Clin Oncol 28:2181–2190\nBoda-Heggemann J, Knopf AC, Simeonova-Chergou A et al (2016) Deep inspiration breath hold-based radiation therapy: a clinical review. Int J Radiat Oncol Biol Phys 94:478–492\nBradley JD, Hu C, Komaki RR et al (2020) Long-term results of NRG oncology RTOG 0617: standard-versus high-dose chemoradiotherapy with or without cetuximab for unresectable stage III non-small-cell lung cancer. J Clin Oncol 38:706–714\nChang JY, Li H, Zhu XR et al (2014) Clinical implementation of intensity modulated proton therapy for thoracic malignancies. Int J Radiat Oncol Biol Phys 90:809–818\nChun SG, Hu C, Choy H et al (2017) Impact of intensity-modulated radiation therapy technique for locally advanced non-small-cell lung cancer: a secondary analysis of the NRG oncology RTOG 0617 randomized clinical trial. J Clin Oncol 35:56–62\nCrockett CB, Samson P, Chuter R et al (2021) Initial clinical experience of MR-guided radiotherapy for non-small cell lung cancer. Front Oncol 11:617681\nDe Ruysscher D, Faivre-Finn C, Moeller D, Lung Group and the Radiation Oncology Group of the European Organization for Research and Treatment of Cancer (EORTC) et al (2017) European organization for research and treatment of cancer (EORTC) recommendations for planning and delivery of high-dose, high precision radiotherapy for lung cancer. Radiother Oncol 124:1–10\nEaton BR, Pugh SL, Bradley JD et al (2016) Institutional enrollment and survival among NSCLC patients receiving chemoradiation: NRG oncology radiation therapy oncology group (RTOG) 0617. J Natl Cancer Inst 108:djw34. https:\u002F\u002Fdoi.org\u002F10.1093\u002Fjnci\u002Fdjw034\nGkika E, Schimek-Jasch T, Kremp S et al (2021) Impact of radiotherapy protocol adherence in NSCLC patients treated with concurrent chemoradiation: RTQA results of the PET-Plan trial. Radiother Oncol 163:32–38\nGrills IS, Yan D, Martinez AA et al (2003) Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer: a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal irradiation. Int J Radiat Oncol Biol Phys 57:875–890\nGuberina M, Darwiche K, Hautzel H et al (2021) Impact of EBUS-TBNA in addition to [18F]FDG-PET\u002FCT imaging on target volume definition for radiochemotherapy in stage III NSCLC. Eur J Nucl Med Mol Imaging 48:2894–2903\nJabbour SK, Lee KH, Frost N et al (2021) Pembrolizumab plus concurrent chemoradiation therapy in patients with unresectable, locally advanced, stage III non-small cell lung cancer: the phase 2 KEYNOTE-799 nonrandomized trial. JAMA Oncol 7:1–9\nKepka L, Socha J (2015) PET-CT use and the occurrence of elective nodal failure in involved field radiotherapy for non-small cell lung cancer: a systematic review. Radiother Oncol 115:151–156\nLeitlinienprogramm Onkologie (Deutsche Krebsgesellschaft, Deutsche Krebshilfe, AWMF): (2022) Prävention, Diagnostik, Therapie und Nachsorge des Lungenkarzinoms Langversion 2.01. https:\u002F\u002Fwww.leitlinienprogramm-onkologie.de\u002Fleitlinien\u002Flungenkarzinom\u002F;. Zugegriffen: 27. Juli 2022 (AWMF-Registernummer: 020\u002F007OL)\nLi R, Yu L, Lin S et al (2016) Involved field radiotherapy (IFRT) versus elective nodal irradiation (ENI) for locally advanced non-small cell lung cancer: a meta-analysis of incidence of elective nodal failure (ENF). Radiat Oncol 11:124\nLiao Z, Lee JJ, Komaki R et al (2018) Bayesian adaptive randomization trial of passive scattering proton therapy and intensity-modulated photon radiotherapy for locally advanced non-small-cell lung cancer. J Clin Oncol 36:1813–1822\nMao W, Riess J, Kim J et al (2022) Evaluation of auto-contouring and dose distributions for online adaptive radiation therapy of patients with locally advanced lung cancers. Pract Radiat Oncol 12:e329–e338\nMeyers SM, Kisling K, Atwood TF, Ray X (2022) A standardized workflow for respiratory-gated motion management decision-making. J Appl Clin Med Phys. https:\u002F\u002Fdoi.org\u002F10.1002\u002Facm2.13705\nMovsas B, Hu C, Sloan J et al (2016) Quality of life analysis of a radiation dose-escalation study of patients with non-small-cell lung cancer: a secondary analysis of the radiation therapy oncology group 0617 randomized clinical trial. JAMA Oncol 2:359–367\nNational Comprehensive Cancer Network (2022) NCCN clinical practice guidelines in oncology (NCCN guidelines®) for non-small cell lung cancer V.03.2022\nNestle U, De Ruysscher D, Ricardi U et al (2018) ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer. Radiother Oncol 127:1–5\nNestle U, Schimek-Jasch T, Kremp S et al (2020) PET-Plan study group. Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised, controlled trial. Lancet Oncol 21:581–592\nPeters S, Felip E, Dafni U et al (2021) Progression-free and overall survival for concurrent nivolumab with standard concurrent chemoradiotherapy in locally advanced stage IIIA‑B NSCLC: results from the European thoracic oncology platform NICOLAS phase II trial (European thoracic oncology platform 6–14). J Thorac Oncol 16:278–288\nReck M, Hyeong Lee K, Frost N et al (2022) Two-year update from KEYNOTE-799: pembrolizumab plus concurrent chemoradiation therapy (cCRT) for unresectable, locally advanced, stage III NSCLC. J Clin Oncol 40(16):8508–8508\nSculier JP, Lafitte JJ, Berghmans T et al (2018) A phase III randomised study comparing concomitant radiochemotherapy with cisplatin and docetaxel as induction versus consolidation treatment in patients with locally advanced unresectable non-small cell lung cancer. Cancer Treat Res 117:32–37\nSenan S, Brade A, Wang LH et al (2016) PROCLAIM: randomized phase III trial of pemetrexed-cisplatin or etoposide-cisplatin plus thoracic radiation therapy followed by consolidation chemotherapy in locally advanced nonsquamous non-small-cell lung cancer. J Clin Oncol 34:953–962\nSpigel DR, Faivre-Finn C, Gray JE et al (2022) Five-year survival outcomes from the PACIFIC trial: durvalumab after chemoradiotherapy in stage III non-small-cell lung cancer. J Clin Oncol 40:1301–1311\nWen N, Glide-Hurst C, Snyder KC et al (2018) Treatment verification and delivery. In: Cai J, Chang JY, Yin FF (Hrsg) Principles and practice of image-guided radiation therapy of lung cancer. Taylor & Francis Group, Boca Raton\nWu YL, Tsuboi M, He J, ADAURA Investigators et al (2020) Osimertinib in resected EGFR-mutated non-small-cell lung cancer. N Engl J Med 383:1711–1723",{"EN":717},"Beim lokal fortgeschrittenen nichtkleinzelligen Lungenkarzinom (NSCLC) führt die Ergänzung der Strahlentherapie durch eine Chemotherapie und die Konsolidierung mit Durvalumab zu einer signifikanten Steigerung des Überlebens und stellt die gravierendste Innovation der letzten Dekade dar. Ziel war die Analyse neuer Möglichkeiten für die State-of-the-Art-Umsetzung definitiver Radiochemotherapiekonzepte. Dazu erfolgte die Auswertung prospektiver und randomisierter Studien hinsichtlich der Verbesserungen der Behandlungsergebnisse. Der Überlebensvorteil der konsolidierenden Checkpointinhibitortherapie nach kombinierter Radiochemotherapie mit Durvalumab beträgt in einer aktualisierten Analyse der PACIFIC-Studie für das 5‑Jahres-Überleben 43 % (95%-Konfidenzintervall, 95%-KI: 38–47 %) gegenüber 33 % (27–40 %) in der Placebogruppe, die stratifizierte Hazard Ratio für Tod beträgt 0,72 (95%-KI: 0,59–0,89; p = 0,0025). In den Studien zur Dosiseskalation sind erhöhte Nebenwirkungen an Lunge und Ösophagus beobachtet worden, sodass aus der Steigerung der lokalen Effektivität kein unmittelbarer klinischer Nutzen abzuleiten war. Verbesserte Bildgebung vor und während der Therapie und optimierte Möglichkeiten der Dosisapplikation, v. a. mittels intensitätsmodulierter Radiotherapie (IMRT), erlauben die selektive Schonung gesunder Strukturen, was die Fähigkeit zur sicheren Therapieintensivierung auch im Zusammenhang mit neuen immunmodulatorischen Substanzkombinationen erhöht. 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In: D104 mechanical ventilation. American Thoracic Society, S A6240–A6240",{"doi":1062},"10.1164\u002Fajrccm-conference.2011.183.1_MeetingAbstracts.A6240",{"id":20,"text":1064,"url":20,"identifiers":1065},"Storre JH, Matrosovich E, Ekkernkamp E, Walker DJ, Schmoor C, Dreher M, Windisch W (2014) Home mechanical ventilation for COPD: high-intensity versus target volume noninvasive ventilation. Respir Care 59:1389–1397",{"doi":1066},"10.4187\u002Frespcare.02941",{"id":20,"text":1068,"url":20,"identifiers":1069},"Windisch W, Vogel M, Sorichter S, Hennings E, Bremer H, Hamm H, Matthys H, Virchow J Jr (2002) Normocapnia during nIPPV in chronic hypercapnic COPD reduces subsequent spontaneous PaCO2. Respir Med 96:572–579",{"doi":1070},"10.1053\u002Frmed.2002.1326",{"id":20,"text":1072,"url":20,"identifiers":1073},"Murphy PB, Brignall K, Moxham J, Polkey MI, Davidson AC, Hart N (2012) High pressure versus high intensity noninvasive ventilation in stable hypercapnic chronic obstructive pulmonary disease: a randomized crossover trial. Int J Chron Obstruct Pulmon Dis 7:811",{"doi":1074},"10.2147\u002FCOPD.S36151",{"id":20,"text":1076,"url":20,"identifiers":1077},"de Leeuw PW, Dees A (2003) Fluid homeostasis in chronic obstructive lung disease. Eur Respir J Suppl 46:33s–40s",{"doi":1078},"10.1183\u002F09031936.03.00000603a",{"id":20,"text":1080,"url":20,"identifiers":1081},"Lukácsovits J, Carlucci A, Hill N, Ceriana P, Pisani L, Schreiber A, Pierucci P, Losonczy G, Nava S (2012) Physiological changes during low- and high-intensity noninvasive ventilation. Eur Respir J 39:869–875",{"doi":1082},"10.1183\u002F09031936.00056111",{"id":20,"text":1084,"url":20,"identifiers":1085},"Duiverman ML, Maagh P, Magnet FS, Schmoor C, Arellano-Maric MP, Meissner A, Storre JH, Wijkstra PJ, Windisch W, Callegari J (2017) Impact of High-Intensity-NIV on the heart in stable COPD: a randomised cross-over pilot study. Respir Res 18:1–12",{"doi":1086},"10.1186\u002Fs12931-017-0542-9",{"id":1088,"createTime":1089,"updateTime":1090,"relativeEntities":1091,"slug":1092,"properties":1093,"entityType":118,"verifyStatus":119,"verifyTime":1090,"verifyNote":120,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":1103,"fullTextUrl":20,"authors":1104,"publicationType":143,"publisherRelationship":1137,"citationCount":20,"citationInfo":20,"publishDate":1165,"publishYear":706,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":20,"isForceReanalyzing":183},"250b8623-41b7-425e-8bcc-25a19d04c075","2024-04-06T19:08:16.209+00:00","2024-12-19T21:15:12.194+00:00",[],"Pneumologie-out-of-the-box-intersektorale-moderne-Diagnostik-und-Therapie-in-der-Schlafmedizin",{"references":1094,"keywords":1096,"abstract":1097,"title":1099,"doi":1101},{"VOID":1095},"Benjafield AV et al (2019) Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med 7(8):687–698\nMayer G et al (2017) S3-Leitlinie Nicht erholsamer Schlaf\u002FSchlafstörungen, Kapitel Schlafbezogene Atmungsstörungen bei Erwachsenen. Somnologie, Bd. Sonderheft 2\nRichtlinie des G‑BA zu Untersuchungs- und Behandlungsmethoden der vertragsärztlichen Versorgung. https:\u002F\u002Fwww.g-ba.de\u002Fdownloads\u002F62-492-3029\u002FMVV-RL-2022-10-20-iK-2023-01-14.pdf. Zugegriffen: 31. Okt. 2023\nAmerican Academy of Sleep Medicine (AASM): Clinical Resources, Telemedicine. https:\u002F\u002Faasm.org\u002Fclinical-resources\u002Ftelemedicine\u002F. Zugegriffen: 31. Okt. 2023\nMarti-Soler H, Hirotsu C, Marques-Vidal P, Vollenweider P, Waeber G, Preisig M, Tafti M, Tufik SB, Bittencourt L, Tufik S, Haba-Rubio J, Heinzer Marti-Soler RH et al (2016) The NoSAS score for screening of sleep-disordered breathing: a derivation and validation study. Lancet Respir Med 4(9):742–748\nOffizielle STOP-BANG tool. http:\u002F\u002Fwww.stopbang.ca\u002F. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Feur-lex.europa.eu\u002Flegal-content\u002FEN\u002FTXT\u002F?uri=CELEX%3A32017R0745. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Fwww.withings.com\u002Fde\u002Fde\u002Fsleep-analyzer?utm_source=google&utm_medium=cpc&utm_campaign=WIPAID_Google_DE_PMax_Scales&gclid=CjwKCAjw15eqBhBZEiwAbDomEi9CkUMPIJY-bLqbjDx2l8_jOBNJ6PaWJBa9mH-PBUgNukcpWtHHFRoCa5gQAvD_BwE. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Fsleepiz.com\u002Fsolutions\u002F. Zugegriffen: 31. Okt. 2023\nLinz D, Baumert M, Desteghe L, Kadhim K, Vernooy K, Kalman JM, Dobrev D, Arzt M, Sastry M, Crijns HJGM, Schotten U, Cowie MR, McEvoy RD, Heidbuchel H, Hendriks J, Sanders P, Lau DH (2019) Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring. Int J Cardiol Heart Vasc 24:100424\nhttps:\u002F\u002Fwww.bfarm.de\u002FSharedDocs\u002FDownloads\u002FDE\u002FService\u002FBeratungsverfahren\u002FDiGA-Leitfaden.pdf;jsessionid=E57485148174A2245929C91DFD02A6AE.2_cid354?__blob=publicationFile&v=4. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Fdiga.bfarm.de\u002Fde\u002Fverzeichnis\u002F00508. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Fdiga.bfarm.de\u002Fde\u002Fverzeichnis\u002F01772. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Fwww.medizininformatik-initiative.de\u002Fde\u002Fmedizininformatik-initiative-neue-use-cases-gefoerdert. Zugegriffen: 31. Okt. 2023\nLight M, Owens RL, Schmickl CN, Malhotra A (2019) Precision Medicine for Obstructive Sleep Apnea. Sleep Med Clin 14(3):391–398\nPépin JL, Bailly S, Tamisier R (2020) Big Data in sleep apnoea: Opportunities and challenges. Respirology 25(5):486–494\nSchoch OD, Baty F, Niedermann J, Rudiger JJ, Brutsche MH (2014) Baseline predictors of adherence to positive airway pressure therapy for sleep apnea: a 10-year single-center observational cohort study. Respiration 87:121–128\nWeaver TE, Maislin G, Dinges DF et al (2007) Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning. Sleep 30:711–719\nRotenberg BW, Murariu D, Pang KP (2016) Trends in CPAP adherence over twenty years of data collection: a flattened curve. J Otolaryngol 45:43\nPépin JL, Bailly S, Rinder P, Adler D, Szeftel D, Malhotra A, Cistulli PA, Benjafield A, Lavergne F, Josseran A, Tamisier R, Hornus P, On Behalf Of The medXcloud Group (2021) CPAP Therapy Termination Rates by OSA Phenotype: A French Nationwide Database Analysis. J Clin Med 10(5):936\nMalhotra A, Crocker ME, Willes L, Kelly C, Lynch S, Benjafield AV (2018) Patient Engagement Using New Technology to Improve Adherence to Positive Airway Pressure Therapy: A Retrospective Analysis. Chest 153:843–850\nWoehrle H, Arzt M, Graml A et al (2018) Effect of a patient engagement tool on positive airway pressure adherence: analysis of a German healthcare provider database. Sleep Med 41:20–26\nWoehrle H, Ficker JH, Graml A et al (2017) Telemedicine-based proactive patient management during positive airway pressure therapy: Impact on therapy termination rate. Somnologie 21:121–127\nLiu D, Armitstead J, Benjafield A et al (2017) Trajectories of emergent central sleep apnea during CPAP therapy. Chest 152:751–760\nPepin JD, Woehrle H, Liu D et al (2018) Adherence to Positive Airway Therapy After Switching From CPAP to ASV: A Big Data Analysis. J Clin Sleep Med 14:57–63\nhttps:\u002F\u002Finnovationsfonds.g-ba.de\u002Fprojekte\u002Fneue-versorgungsformen\u002Fsleep-well-digital-unterstuetzte-schlafmedizin-entwicklung-optimierter-patientenwege-bei-obstruktiver-schlafapnoe.433. Zugegriffen: 31. Okt. 2023\nSchöbel C, Zentgraf C, Strassburg S et al (2022) SLEEP WELL. Z Pneumol 19:191–200\nhttps:\u002F\u002Feur-lex.europa.eu\u002Flegal-content\u002FDE\u002FTXT\u002F?uri=celex%3A32016R0679. Zugegriffen: 31. Okt. 2023\nhttps:\u002F\u002Fwww.bundesgesundheitsministerium.de\u002Ffileadmin\u002FDateien\u002F3_Downloads\u002FGesetze_und_Verordnungen\u002FGuV\u002FH\u002FRefE_Hybrid-DRG-V.pdf. Zugegriffen: 31. Okt. 2023\nWoehrle H, Schoebel C, Ficker JH et al (2023) PAP telehealth models and long-term therapy termination: a healthcare database analysis. ERJ Open Res\nAbstract DGP-Kongress 2024: Woehrle, Arzt, Schoebel et al. Utilisation of PG and PSG for the diagnosis, therapy initiation and follow-up of positive airway pressure (PAP) treatment of Obstructive Sleep Apnea (OSA) patients; analysis of a German healthcare database\nwww.schlafapnoe-selbsthilfegruppe.de. Zugegriffen: 28. Jan. 2024",{"EN":112},{"EN":1098},"Schlafstörungen weisen eine zunehmende Prävalenz auf. Im Bereich der respiratorischen Schlafmedizin ist die obstruktive Schlafapnoe (OSA) die häufigste organisch bedingte Schlafstörung. Die nächtliche Überdrucktherapie („positive airway pressure [PAP] therapy“) stellt die Standardtherapie dar; die Unterkieferprotrusionsschiene (UKPS) wird seit Kurzem als Zweitlinientherapie seitens der gesetzlichen Krankenversicherung finanziert. Positive Effekte auf Symptomatik und Folgeerkrankungen sind, jedoch nur bei regelmäßiger und langfristiger Therapienutzung, zu erwarten. Aufgrund der steigenden Prävalenzzahlen zeigen sich in der bestehenden intersektoralen Versorgung Schnittstellenprobleme, die zu Fehlversorgungen und langen Wartezeiten im Diagnostik- und Therapiepfad führen. Dies wirkt sich in der Therapienachsorge auch auf die Therapieadhärenz aus. Neuartige Methoden aus dem Bereich E‑ und M‑Health bieten bereits heutzutage smarte Lösungen für aktuell noch unzureichend adressierte Probleme in der Schlafmedizin an. Neue Sensorik und Applikationen für digitale Endgeräte (Apps) eröffnen Möglichkeiten für ein breites Screening auf die Volkserkrankung Schlafapnoe. Cloud-basierte Telemedizinkonzepte können helfen, betroffene Patienten im Rahmen der etablierten Stufendiagnostik frühzeitig und bedarfsgerecht einer schlafmedizinischen Expertise zuzuführen und die interdisziplinäre Kommunikation zu verbessern. Telemonitoring kann zudem genutzt werden, um Patienten mit Therapieproblemen frühzeitig zu identifizieren. So können Therapieabbruchraten reduziert bzw. frühzeitig Patienten für alternative Therapien identifiziert werden. Letztlich werden sich all diese Methoden nur dann durchsetzen und Patienten zugutekommen, wenn sie Schlafmediziner in ihrer alltäglichen Arbeit unterstützen und entlasten sowie sinnvoll in bestehende Versorgungsprozesse und deren Vergütung eingebunden werden.",{"EN":1100},"Pneumologie out of the box – intersektorale moderne Diagnostik und Therapie in der Schlafmedizin",{"VOID":1102},"10.1007\u002Fs10405-024-00547-y","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs10405-024-00547-y",[1105,1121],{"id":1106,"sortIndex":96,"researcher":20,"roles":1107,"affiliations":1108,"properties":1118},"818fcaab-c34c-4187-a07b-3a395c0764a6",[204],[1109],{"id":20,"sortIndex":21,"affiliation":1110,"properties":20},{"id":1111,"createTime":1112,"updateTime":1112,"relativeEntities":1113,"slug":1114,"properties":1115,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"4b63e85c-c229-425b-9920-90473bd651ba","2024-04-06T19:08:16.227+00:00",[],"Lungenzentrum-Ulm-mit-Schlaf-und-Beatmungszentrum-Blaubeuren-Ulm-Deutschland",{"title":1116},{"VI":1117},"Lungenzentrum Ulm mit Schlaf- und Beatmungszentrum Blaubeuren, Ulm, Deutschland",{"title":1119},{"VI":1120},"H. Woehrle",{"id":1122,"sortIndex":21,"researcher":20,"roles":1123,"affiliations":1124,"properties":1134},"311a5736-0753-4323-989c-d63fccc03b17",[204],[1125],{"id":20,"sortIndex":21,"affiliation":1126,"properties":20},{"id":1127,"createTime":1128,"updateTime":1128,"relativeEntities":1129,"slug":1130,"properties":1131,"entityType":49,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21},"71c1048c-b790-43b8-b848-1ae2fcfb4508","2024-04-06T19:08:16.219+00:00",[],"Ruhrlandklinik-Westdeutsches-Lungenzentrum-Zentrum-f%C3%BCr-Schlaf-und-Telemedizin-Universit%C3%A4tsmedizin-Essen-Essen-Deutschland",{"title":1132},{"VI":1133},"Ruhrlandklinik – Westdeutsches Lungenzentrum, Zentrum für Schlaf- und Telemedizin, Universitätsmedizin Essen, Essen, Deutschland",{"title":1135},{"VI":1136},"C. Schöbel",{"url":20,"publisher":1138,"properties":20},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1139,"slug":10,"properties":1140,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1144,"manageAffiliations":1145,"indexDatabases":1146,"url":91,"thumbnailPath":20,"statistic":1160,"gsStatistic":20,"type":99,"analyzePriority":20},[],{"issn":1141,"eissn":1142,"title":1143},{"VOID":13},{"VOID":15},{"EN":17},[],[],[1147,1154],{"id":55,"indexDatabase":1148,"url":70,"indexYears":20,"academicFieldIds":1153,"indexDatabaseRanking":20},{"id":57,"createTime":58,"updateTime":59,"relativeEntities":1149,"label":1150,"description":1151,"key":66,"publicationTags":1152,"standard":20},[],{"EN":62,"VI":62},{"VI":64,"EN":65},[68,69],[72,73],{"id":75,"indexDatabase":1155,"url":88,"indexYears":89,"academicFieldIds":20,"indexDatabaseRanking":90},{"id":77,"createTime":78,"updateTime":79,"relativeEntities":1156,"label":1157,"description":1158,"key":85,"publicationTags":1159,"standard":20},[],{"EN":82,"VI":82},{"EN":82,"VI":84},[87],{"impactFactor":21,"impactFactorByYear":1161,"i10Index":21,"i10IndexLast5Year":21,"totalPublication":94,"totalPublicationByYear":1162,"totalCitation":21,"totalCitationByYear":1163,"totalCitationPerPublication":21,"totalCitationPerPublicationByYear":1164,"hindexLast5Year":21,"hindex":21},{},{"2022":96,"2023":96},{},{},"2024-02-28",{"id":1167,"createTime":1168,"updateTime":1168,"relativeEntities":1169,"slug":20,"properties":1170,"entityType":118,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":1175,"fullTextUrl":20,"authors":1176,"publicationType":143,"publisherRelationship":1177,"citationCount":20,"citationInfo":20,"publishDate":1209,"publishYear":379,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":20,"isForceReanalyzing":183},"4c90d903-2fb9-4788-bc40-81db6a3742a1","2023-12-07T20:50:13.413+00:00",[],{"title":1171,"doi":1173},{"EN":1172},"Mitteilungen des Berufsverbands der Pneumologen in Baden-Württemberg e.V.",{"VOID":1174},"10.1007\u002Fs10405-023-00518-9","https:\u002F\u002Flink.springer.com\u002F10.1007\u002Fs10405-023-00518-9",[],{"url":1175,"publisher":1178,"properties":1205},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1179,"slug":10,"properties":1180,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1184,"manageAffiliations":1185,"indexDatabases":1186,"url":91,"thumbnailPath":20,"statistic":1200,"gsStatistic":20,"type":99,"analyzePriority":20},[],{"issn":1181,"eissn":1182,"title":1183},{"VOID":13},{"VOID":15},{"EN":17},[],[],[1187,1194],{"id":55,"indexDatabase":1188,"url":70,"indexYears":20,"academicFieldIds":1193,"indexDatabaseRanking":20},{"id":57,"createTime":58,"updateTime":59,"relativeEntities":1189,"label":1190,"description":1191,"key":66,"publicationTags":1192,"standard":20},[],{"EN":62,"VI":62},{"VI":64,"EN":65},[68,69],[72,73],{"id":75,"indexDatabase":1195,"url":88,"indexYears":89,"academicFieldIds":20,"indexDatabaseRanking":90},{"id":77,"createTime":78,"updateTime":79,"relativeEntities":1196,"label":1197,"description":1198,"key":85,"publicationTags":1199,"standard":20},[],{"EN":82,"VI":82},{"EN":82,"VI":84},[87],{"impactFactor":21,"impactFactorByYear":1201,"i10Index":21,"i10IndexLast5Year":21,"totalPublication":94,"totalPublicationByYear":1202,"totalCitation":21,"totalCitationByYear":1203,"totalCitationPerPublication":21,"totalCitationPerPublicationByYear":1204,"hindexLast5Year":21,"hindex":21},{},{"2022":96,"2023":96},{},{},{"volume":1206,"pages":1207},{"VOID":375},{"VOID":1208},"294-296","2023-08-25",{"id":1211,"createTime":1212,"updateTime":1213,"relativeEntities":1214,"slug":1215,"properties":1216,"entityType":118,"verifyStatus":119,"verifyTime":1213,"verifyNote":120,"syncStatus":19,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":1225,"fullTextUrl":20,"authors":1226,"publicationType":143,"publisherRelationship":1314,"citationCount":20,"citationInfo":20,"publishDate":801,"publishYear":379,"citationAnalyzeStatus":19,"lastCitationAnalyze":20,"indexDatabases":20,"openAccess":20,"references":20,"isForceReanalyzing":183},"ecaebdd2-048e-4eb5-870b-321304987946","2024-02-08T13:53:45.910+00:00","2024-12-11T20:47:19.258+00:00",[],"Lungenmetastasen-Onkologische-Bedeutung-und-Therapie",{"references":1217,"abstract":1219,"title":1221,"doi":1223},{"VOID":1218},"Köhler D, Schönhofer B, Voshaar T (2010) Pneumologie. Thieme, Stuttgart, S 241 ISBN 978-3-13-146281‑7.\nSuster S, Moran C (2013) Metastatic tumors to the lung. In: Biopsy interpretation of the Lung. Wolters Kluwer, S 369–401. ISBN 978-0-7817-8467‑2\nSuster S, Moran C (2012) Neoplasms, metastatic. In: Diagnostic pathology, thoracic. Amirsys, S I‑3-2–I-3-33. ISBN 978-1-931884-49‑5\nVliegenthart R, Fouras A, Jacobs C, Papanikolaou N (2022) Innovations in thoracic imaging: CT, radiomics, AI and x‑ray velocimetry. Respirology 27(10):818–833. https:\u002F\u002Fdoi.org\u002F10.1111\u002Fresp.14344\nBrandman S, Ko JP (2011) Pulmonary nodule detection, characterization, and management with multidetector computed tomography. J Thorac Imaging 26(2):90–105\nVogl TJ, Eckert R, Naguib NN, Beeres M, Gruber-Rouh T, Nour-Eldin NA (2016) Thermal ablation of colorectal lung metastases: retrospective comparison among laser-induced thermotherapy, radiofrequency ablation, and microwave ablation. AJR Am J Roentgenol 207(6):1340–1349\nHirsch FW, Sorge I, Vogel-Claussen J, Roth C, Gräfe D, Päts A, Voskrebenzev A, Anders RM (2020) The current status and further prospects for lung magnetic resonance imaging in pediatric radiology. Pediatr Radiol 50(5):734–749\nJurmeister P, Schöler A, Arnold A, Klauschen F, Lenze D, Hummel M, Schweizer L, Bläker H, Pfitzner BM, Mamlouk S, Sers C, Denkert C, Stichel D, Frost N, Horst D, von Laffert M, Capper D (2019) DNA methylation profiling reliably distinguishes pulmonary enteric adenocarcinoma from metastatic colorectal cancer. Mod Pathol 32(6):855–865\nJurmeister P, Vollbrecht C, Behnke A, Frost N, Arnold A, Treue D, Rückert JC, Neudecker J, Schweizer L, Klauschen F, Horst D, Hummel M, Dietel M, von Laffert M (2019) Next generation sequencing of lung adenocarcinoma subtypes with intestinal differentiation reveals distinct molecular signatures associated with histomorphology and therapeutic options. 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J Thorac Dis 9(Suppl 12):S1267–S1272\nMarulli G, Mammana M, Comacchio G, Rea F (2017) Survival and prognostic factors following pulmonary metastasectomy for sarcoma. J Thorac Dis 9(Suppl 12):S1305–S1315\nShiono S (2021) The role of pulmonary metastasectomy for pulmonary metastasis from head and neck cancer. J Thorac Dis 13(4):2643–2648\nGirelli L, Locati L, Galeone C, Scanagatta P, Duranti L, Licitra L, Pastorino U (2017) Lung metastasectomy in adenoid cystic cancer: Is it worth it? Oral Oncol 65:114–118\nKanzaki R, Fukui E, Kanou T, Ose N, Funaki S, Minami M, Shintani Y, Okumura M (2021) Preoperative evaluation and indications for pulmonary metastasectomy. J Thorac Dis 13(4):2590–2602\nSchlachtenberger G, Doerr F, Menghesha H, Lauinger P, Wolber P, Sabashnikov A, Popov AF, Macherey-Meyer S, Bennink G, Klussmann JP, Wahlers T, Hekmat K, Heldwein MB (2022) Patients with pulmonary metastases from head and neck cancer benefit from pulmonary metastasectomy, a systematic review. Medicina 58(8):1000\nPastorino U, Buyse M, Friedel G, Ginsberg RJ, Girard P, Goldstraw P, Johnston M, McCormack P, Pass H, Putnam JB Jr (1997) International registry of lung metastases. Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg 113(1):37–49\nBong CY, Smithers BM, Chua TC (2021) Pulmonary metastasectomy in the era of targeted therapy and immunotherapy. J Thorac Dis 13(4):2618–2627\nHandy JR, Bremner RM, Crocenzi TS, Detterbeck FC, Fernando HC, Fidias PM, Firestone S, Johnstone CA, Lanuti M, Litle VR, Kesler KA, Mitchell JD, Pass HI, Ross HJ, Varghese TK (2019) Expert consensus document on pulmonary metastasectomy. Ann Thorac Surg 107(2):631–649\nGonzalez M, Brunelli A, Szanto Z, Passani S, Falcoz PE (2021) Report from the European society of thoracic surgeons database 2019: current surgical practice and perioperative outcomes of pulmonary metastasectomy. Eur J Cardiothorac Surg 59(5):996–1003\nPanagiotopoulos N, Patrini D, Lawrence D, Scarci M, Mitsos S (2018) Pulmonary metastasectomy and laser-assisted resection. J Thorac Dis 10(Suppl 17):S1930–S1933. https:\u002F\u002Fdoi.org\u002F10.21037\u002Fjtd.2018.05.08\nRusidanmu A, Chin W, Xu J, Wang L, He Z, Lv X, Hu J (2021) Does a thoracoscopic approach provide better outcomes for pulmonary metastases? J Thorac Dis 13(4):2692–2697\nAdebahr S, Hechtner M, Schräder N, Schimek-Jasch T, Kaier K, Duncker-Rohr V, Gkika E, Momm F, Gaertner J, Becker G, Grosu AL, Nestle U (2019) Early impact of pulmonary fractionated stereotactic body radiotherapy on quality of life:benefit for patients with low initial scores (STRIPE trial). J Thorac Oncol 14(3):408–419\nGomez DR, Tang C, Zhang J, Blumenschein GR Jr, Hernandez M, Lee JJ, Ye R, Palma DA, Louie AV, Camidge DR, Doebele RC, Skoulidis F, Gaspar LE, Welsh JW, Gibbons DL, Karam JA, Kavanagh BD, Tsao AS, Sepesi B, Swisher SG, Heymach JV (2019) Local consolidative therapy vs. maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer: long-term results of a multi-institutional, phase II, randomized study. J Clin Oncol 37(18):1558–1565\nHarrow S, Palma DA, Olson R, Gaede S, Louie AV, Haasbeek C, Mulroy L, Lock M, Rodrigues GB, Yaremko BP, Schellenberg D, Ahmad B, Senthi S, Swaminath A, Kopek N, Liu M, Schlijper R, Bauman GS, Laba J, Qu XM, Warner A, Senan S (2022) Stereotactic radiation for the comprehensive treatment of oligometastases (SABR-COMET): extended long-term outcomes. 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J Immunother Cancer 8(1):e491\nOldenburg J, Berney DM, Bokemeyer C, Climent MA, Daugaard G, Gietema JA, De Giorgi U, Haugnes HS, Huddart RA, Leão R, Sohaib A, Gillessen S, Powles T, ESMO Guidelines Committee (2022) Testicular seminoma and non-seminoma: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol 33(4):362–375\nRapoport BL, Shannon VR, Cooksley T, Johnson DB, Anderson L, Blidner AG, Tintinger GR, Anderson R (2021) Pulmonary toxicities associated with the use of immune checkpoint inhibitors: an update from the immuno-oncology subgroup of the neutropenia, infection & myelosuppression study group of the multinational association for supportive care in cancer. 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