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Samples were stored under different conditions (room temperature, 4°C, or 37–38°C) and were analyzed approximately 0.5 to one h, 3.5–4 h, 7–7.5 h, and 28–29 h after collection.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>In\u003Cjats:styled-content style=\"fixed-case\">EDTA\u003C\u002Fjats:styled-content>blood samples from male minipigs stored at room temperature, there was a progressive thrombocyte decrease over time up to −71% after 29 h, caused by in vitro aggregation. In females, no consistent change was seen up to 7.5 h, but there was a decrease up to −47% after 29 h. Thrombocyte count was most stable during storage at 4°C. No consistent marked decrease in thrombocyte counts was seen for citrated blood at room temperature, although such a decrease was present in a few individual animals.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>Study results provide evidence for an anticoagulant‐dependent pseudothrombocytopenia in minipigs progressing over time and depending on the storage temperature of the blood sample. It is therefore recommended to perform thrombocyte counts as soon as possible after blood collection, and in case of low counts, investigate for the presence of artifactual platelet clumping.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>","\u003Cjats:sec>\u003Cjats:title>Đặt vấn đề\u003C\u002Fjats:title>\u003Cjats:p>Đã quan sát thấy sự giảm rõ rệt số lượng tiểu cầu giữa các lần đo sau của cùng một mẫu máu \u003Cjats:styled-content style=\"fixed-case\">EDTA\u003C\u002Fjats:styled-content> ở nhiều con lợn minipig, nhưng ít thông tin có sẵn giải thích cho hiện tượng này.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Mục tiêu\u003C\u002Fjats:title>\u003Cjats:p>Mục tiêu là đánh giá tác động của một số biến số tiền phân tích đến số lượng tiểu cầu ở lợn minipig, nhằm nâng cao hiểu biết về sự giảm tiểu cầu in vitro quan sát được.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Vật liệu và phương pháp\u003C\u002Fjats:title>\u003Cjats:p>Mẫu máu huyết học từ lợn minipig Göttingen đực và cái được thu thập bằng cách sử dụng \u003Cjats:styled-content style=\"fixed-case\">EDTA\u003C\u002Fjats:styled-content> hoặc citrate làm chất chống đông. Các mẫu được bảo quản dưới các điều kiện khác nhau (nhiệt độ phòng, 4°C hoặc 37–38°C) và được phân tích khoảng 0,5 đến một giờ, 3,5–4 giờ, 7–7,5 giờ và 28–29 giờ sau khi thu thập.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Kết quả\u003C\u002Fjats:title>\u003Cjats:p>Trong các mẫu máu \u003Cjats:styled-content style=\"fixed-case\">EDTA\u003C\u002Fjats:styled-content> từ lợn minipig đực được bảo quản ở nhiệt độ phòng, có sự giảm tiểu cầu tiến triển theo thời gian lên đến -71% sau 29 giờ, do sự kết tụ tiểu cầu in vitro. Ở lợn cái, không có sự thay đổi nhất quán nào được thấy cho đến 7,5 giờ, nhưng có sự giảm lên đến -47% sau 29 giờ. Số lượng tiểu cầu ổn định nhất trong quá trình bảo quản ở 4°C. 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Available at:http:\u002F\u002Fminipigs.dk\u002Ffileadmin\u002Ffiler\u002FEducation_package_New\u002FHandling_Dosing_Training.pdf. Accessed April 25 2017.",{},{"id":24,"text":337,"url":24,"identifiers":338},"10.1111\u002Fj.1939-1676.2007.tb03067.x",{"doi":337},{"id":24,"text":340,"url":24,"identifiers":341},"Asma A, 2015, Ethylenediaminetetraacetic acid (EDTA) induced pseudothrombocytopenia determination of agregation kinetic and temperature optimum (a case report) [abstract], Clin Chem Lab Med, 53, S868",{},{"id":24,"text":343,"url":24,"identifiers":344},"10.1159\u002F000437220",{"doi":343},{"id":24,"text":346,"url":24,"identifiers":347},"10.1111\u002Fvcp.12059",{"doi":346},false,{"id":350,"createTime":351,"updateTime":352,"relativeEntities":353,"slug":354,"properties":355,"entityType":150,"verifyStatus":151,"verifyTime":351,"verifyNote":152,"syncStatus":23,"languages":372,"translateLanguages":373,"viewCount":25,"primaryUrl":374,"fullTextUrl":24,"authors":375,"publicationType":258,"publisherRelationship":414,"citationCount":115,"citationInfo":452,"publishDate":454,"publishYear":455,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":456,"isForceReanalyzing":348},"e3650270-5047-4e70-89c4-79bf44408fe7","2024-09-18T04:05:59.935+00:00","2025-02-13T22:56:29.581+00:00",[],"Automated-Blood-Cell-Counting-Systems-A-Comparison-of-the-Coulter-S-Plus-IV-Ortho-ELT-8-DS-Ortho-ELT-8-WS-Technicon-H-1-and-Sysmex-E-5-000",{"mag":356,"keywords":358,"openalex":360,"abstract":362,"title":365,"pm":368,"doi":370},{"VOID":357},"1977069670",{"VI":359},"",{"VOID":361},"W1977069670",{"EN":363,"VI":364},"\u003Cjats:title>Summary\u003C\u002Fjats:title>\u003Cjats:p>Four automated blood cell counting systems were evaluated at the Michigan State University Veterinary Clinical Center (VCC) for their suitability for analyzing various animals' blood in a university teaching hospital laboratory. The instruments were compared to a Coulter Model S‐Senior (Coulter Electronics) which had been used for 8 years, and was to be replaced. The instruments were a Coulter Model S‐Plus IV, an Ortho ELT‐8\u002Fds (Ortho Diagnostics Systems), a Technicon H‐1 (Technicon Instruments), and a Sysmex E‐5,000 (Toa Medical Electronics). Additionally, an Ortho ELT‐8\u002Fws at a private laboratory (Cenvet) was compared to the Coulter S—Senior at the VCC.\u003C\u002Fjats:p>\u003Cjats:p>Based on these evaluations, only the Sysmex E‐5,000 was considered unacceptable for the VCC laboratory. Certain advantages and disadvantages of the instruments are described in this article. The comparisons a‐mong instruments were not as consistent or repetitive as expected for a controlled experiment but did provide information likely useful to others considering using or purchasing an automated blood cell counting system for a veterinary laboratory.\u003C\u002Fjats:p>","\u003Cjats:title>Tóm tắt\u003C\u002Fjats:title>\u003Cjats:p>Bốn hệ thống đếm tế bào máu tự động đã được đánh giá tại Trung tâm lâm sàng thú y (VCC) thuộc Đại học Bang Michigan để xác định khả năng phân tích máu của nhiều loại động vật trong phòng thí nghiệm của một bệnh viện giảng dạy thuộc đại học. Các máy móc đã được so sánh với máy Coulter Model S‐Senior (Coulter Electronics), đã được sử dụng trong 8 năm và sẽ được thay thế. Các máy bao gồm: Coulter Model S‐Plus IV, Ortho ELT‐8\u002Fds (Hệ thống Chẩn đoán Ortho), Technicon H‐1 (Thiết bị Technicon), và Sysmex E‐5,000 (Điện tử Y tế Toa). Ngoài ra, một máy Ortho ELT‐8\u002Fws tại một phòng thí nghiệm tư nhân (Cenvet) cũng được so sánh với Coulter S—Senior tại VCC.\u003C\u002Fjats:p>\u003Cjats:p>Dựa trên những đánh giá này, chỉ có Sysmex E‐5,000 được coi là không phù hợp cho phòng thí nghiệm VCC. Một số ưu điểm và nhược điểm của các máy móc được mô tả trong bài viết này. Việc so sánh giữa các máy không nhất quán hoặc lặp lại như dự kiến trong một thí nghiệm có kiểm soát, nhưng vẫn cung cấp thông tin có thể hữu ích cho những người khác đang xem xét việc sử dụng hoặc mua hệ thống đếm tế bào máu tự động cho phòng thí nghiệm thú y.",{"EN":366,"VI":367},"Automated Blood Cell Counting Systems: A Comparison of the Coulter S‐Plus IV, Ortho ELT‐8\u002FDS, Ortho ELT‐8\u002FWS, Technicon H‐1, and Sysmex E‐5,000","Hệ thống đếm tế bào máu tự động: So sánh Coulter S‐Plus IV, Ortho ELT‐8\u002FDS, Ortho ELT‐8\u002FWS, Technicon H‐1 và Sysmex E‐5,000",{"VOID":369},"15162336",{"VOID":371},"10.1111\u002Fj.1939-165x.1988.tb00490.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.1988.tb00490.x",[376,395],{"id":377,"sortIndex":111,"researcher":24,"roles":378,"affiliations":379,"properties":390},"bb5e339c-fbb6-43a1-afd1-8fb490b60adb",[],[380],{"id":381,"sortIndex":25,"affiliation":382,"properties":24},"d9e2a6a8-c39d-402a-8695-2b312af0c9ed",{"id":383,"createTime":384,"updateTime":384,"relativeEntities":385,"slug":386,"properties":387,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"3046adf8-d7e5-4c69-b038-9898773a1dd8","2024-09-18T04:05:59.962+00:00",[],"Cenvet-1676-First-Avenue-New-York-New-York-10128",{"title":388},{"EN":389},"Cenvet 1676 First Avenue New York, New York 10128",{"openalex":391,"title":393},{"VOID":392},"A5005134322",{"EN":394},"Robert J. Wilkins",{"id":396,"sortIndex":25,"researcher":24,"roles":397,"affiliations":398,"properties":409},"42f3d4af-3ca1-401e-acf9-22cf458da5b1",[],[399],{"id":400,"sortIndex":25,"affiliation":401,"properties":24},"e371864f-c924-4141-993d-0e0e1754860b",{"id":402,"createTime":403,"updateTime":403,"relativeEntities":404,"slug":405,"properties":406,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"0fdfe7bc-881a-483e-ba6b-31aac38b41c2","2024-09-18T04:05:59.951+00:00",[],"Veterinary-Clinical-Center-Michigan-State-University-East-Lansing-Michigan-48824-1316",{"title":407},{"EN":408},"Veterinary Clinical Center Michigan State University East Lansing, Michigan 48824‐1316",{"openalex":410,"title":412},{"VOID":411},"A5079876277",{"EN":413},"Harold W. Tvedtend",{"url":24,"publisher":415,"properties":445},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":416,"slug":10,"properties":417,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":423,"manageAffiliations":424,"indexDatabases":425,"url":105,"thumbnailPath":24,"statistic":440,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":418,"issn":419,"introduce":420,"eissn":421,"title":422},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[426,433],{"id":67,"indexDatabase":427,"url":80,"indexYears":81,"academicFieldIds":432,"indexDatabaseRanking":85},{"id":69,"createTime":70,"updateTime":71,"relativeEntities":428,"label":429,"description":430,"key":77,"publicationTags":431,"standard":24},[],{"EN":74,"VI":74},{"EN":74,"VI":76},[79],[83,84],{"id":87,"indexDatabase":434,"url":102,"indexYears":24,"academicFieldIds":439,"indexDatabaseRanking":24},{"id":89,"createTime":90,"updateTime":91,"relativeEntities":435,"label":436,"description":437,"key":98,"publicationTags":438,"standard":24},[],{"EN":94,"VI":94},{"VI":96,"EN":97},[100,101],[104],{"impactFactor":25,"impactFactorByYear":441,"i10Index":109,"i10IndexLast5Year":25,"totalPublication":53,"totalPublicationByYear":442,"totalCitation":112,"totalCitationByYear":443,"totalCitationPerPublication":121,"totalCitationPerPublicationByYear":444,"hindexLast5Year":109,"hindex":109},{"2012":108,"2019":108},{"1983":111,"1988":111,"1993":111,"1996":111,"2000":111,"2008":111,"2010":111,"2017":111},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"volume":446,"pages":448,"issue":450},{"VOID":447},"17",{"VOID":449},"47-54",{"VOID":451},"2",{"total":115,"publishYear":24,"statisticByYear":453},{"2020":111},"1988-06-01",1988,[457,460,463,466,469,472,475,478,481],{"id":24,"text":458,"url":24,"identifiers":459},"10.1111\u002Fj.1939-165X.1983.tb00611.x",{"doi":458},{"id":24,"text":461,"url":24,"identifiers":462},"10.1093\u002Flabmed\u002F16.4.228",{"doi":461},{"id":24,"text":464,"url":24,"identifiers":465},"Wardlaw S, 1985, An INstrument for White Blood Cell Subclassification, Amer Clin Prod Rev, 2, 21",{},{"id":24,"text":467,"url":24,"identifiers":468},"10.1093\u002Flabmed\u002F17.5.271",{"doi":467},{"id":24,"text":470,"url":24,"identifiers":471},"Alpert NL, 1985, Blood Cell Counters with Three Populations, Diff Clin Instr Sys, 6, 1",{},{"id":24,"text":473,"url":24,"identifiers":474},"10.1093\u002Flabmed\u002F17.1.17",{"doi":473},{"id":24,"text":476,"url":24,"identifiers":477},"WeiserMG:Personal Communication.",{},{"id":24,"text":479,"url":24,"identifiers":480},"Jain NC, 1986, Schalm's Veterinary Hematology",{},{"id":24,"text":482,"url":24,"identifiers":483},"EasleyJR:Personal Communication.",{},{"id":485,"createTime":486,"updateTime":487,"relativeEntities":488,"slug":489,"properties":490,"entityType":150,"verifyStatus":151,"verifyTime":486,"verifyNote":152,"syncStatus":23,"languages":506,"translateLanguages":507,"viewCount":25,"primaryUrl":508,"fullTextUrl":24,"authors":509,"publicationType":258,"publisherRelationship":540,"citationCount":114,"citationInfo":576,"publishDate":578,"publishYear":579,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":580,"isForceReanalyzing":348},"f16614af-5523-4820-9015-1709584c3bb5","2024-09-18T04:06:00.121+00:00","2025-02-13T22:55:31.951+00:00",[],"Comparison-of-Two-Automated-Multi-Channel-Blood-Cell-Counting-Systems-for-Analysis-of-Blood-of-Common-Domestic-Animals",{"mag":491,"keywords":493,"openalex":494,"abstract":496,"title":499,"pm":502,"doi":504},{"VOID":492},"2031709375",{"VI":359},{"VOID":495},"W2031709375",{"EN":497,"VI":498},"\u003Cjats:title>Summary\u003C\u002Fjats:title>\u003Cjats:p>An automated, multi‐channel blood cell counting system (S‐Plus) was compared to a reference counting system using blood samples from 187 animals of four species. The standard red cell bath aperture current of 150 volts (V) was used during analysis of 75% of the samples. At this setting, all samples with a Mean Corpuscular Volume (MCV) greater than 50 fl had accurate erythrocyte counts. As the MCV decreased below 50 fl, the severity of false low erythrocyte counts and false high MCV values increased. The remaining 25% of samples were analyzed with the red cell bath aperture current increased to 200 V. At this setting, only 5% or less of erythrocytes from animals with normal MCV values (>36 fl) were below the erythrocyte threshold. The red cell distribution width values provided by the S‐Plus indicated that equine and bovine erythrocytes have greater anisocytosis than canine and feline erythrocytes. Leukocyte counts were significantly lower on the S‐Plus (p < 0.01). Canine and equine samples most frequently had platelet size distribution within the S‐Plus platelet counting threshold window. Electronic whole blood platelet counting appeared unsatisfactory in cats due to large platelet size and erythrocyte‐platelet size overlap. Small platelet size in cattle indicated that further modifications of the red cell bath aperture current would be required to count and size platelets in this species. Following electronic modifications, this state‐of‐the‐art system appears adaptable to hematologic profiling in most species.\u003C\u002Fjats:p>","\u003Cjats:title>Tóm tắt\u003C\u002Fjats:title>\u003Cjats:p>Hệ thống đếm tế bào máu tự động đa kênh (S‐Plus) đã được so sánh với một hệ thống đếm tham chiếu sử dụng mẫu máu từ 187 động vật thuộc bốn loài. Dòng điện của bể tế bào đỏ tiêu chuẩn là 150 volt (V) đã được sử dụng trong quá trình phân tích 75% số mẫu. Tại chế độ này, tất cả các mẫu có Thể tích Hồng cầu Trung bình (MCV) lớn hơn 50 fl đều cho kết quả đếm hồng cầu chính xác. Khi MCV giảm xuống dưới 50 fl, độ nghiêm trọng của các kết quả đếm hồng cầu giả thấp và giá trị MCV giả cao tăng lên. 25% mẫu còn lại được phân tích với dòng điện bể tế bào đỏ tăng lên 200 V. Tại chế độ này, chỉ có 5% hoặc ít hơn số hồng cầu từ động vật có giá trị MCV bình thường (>36 fl) nằm dưới ngưỡng hồng cầu. Giá trị chiều rộng phân bố tế bào đỏ do S‐Plus cung cấp cho thấy hồng cầu của ngựa và bò có độ biệt lập tế bào cao hơn so với hồng cầu của chó và mèo. Kết quả đếm bạch cầu trên S‐Plus thấp hơn đáng kể (p \u003C 0.01). Mẫu của chó và ngựa thường xuyên có sự phân bố kích thước tiểu cầu nằm trong ngưỡng đếm tiểu cầu của S‐Plus. Việc đếm tiểu cầu toàn bộ máu điện tử dường như không hiệu quả ở mèo do kích thước tiểu cầu lớn và sự chồng lấn về kích thước giữa hồng cầu và tiểu cầu. Kích thước tiểu cầu nhỏ ở bò cho thấy cần có những điều chỉnh thêm về dòng điện bể tế bào đỏ để đếm và xác định kích thước tiểu cầu ở loài này. Sau những điều chỉnh điện tử, hệ thống tiên tiến này dường như có thể thích ứng với phân tích huyết học ở hầu hết các loài.",{"EN":500,"VI":501},"Comparison of Two Automated Multi‐Channel Blood Cell Counting Systems for Analysis of Blood of Common Domestic Animals","So sánh Hai Hệ Thống Đếm Tế Bào Máu Tự Động Đa Kênh Trong Phân Tích Máu của Những Động Vật Nuôi Thông Thường",{"VOID":503},"15311397",{"VOID":505},"10.1111\u002Fj.1939-165x.1983.tb00611.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.1983.tb00611.x",[510],{"id":511,"sortIndex":25,"researcher":24,"roles":512,"affiliations":513,"properties":535},"f04a4258-5ca7-4c24-b926-1b846cb1c899",[],[514,525],{"id":515,"sortIndex":25,"affiliation":516,"properties":24},"3fd3bcfc-00dc-4f3d-96ce-a327c21f3c16",{"id":517,"createTime":518,"updateTime":519,"relativeEntities":520,"slug":521,"properties":522,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"0a2f371f-2fdb-4899-aba6-99168d9b9bf2","2024-09-18T04:06:00.134+00:00","2025-06-11T23:06:05.361+00:00",[],"Department-of-Pathology-College-of-Veterinary-Medicine-Colorado-State-University-Ft-Collins-Colorado-80523",{"title":523},{"EN":524},"Department of Pathology College of Veterinary Medicine Colorado State University Ft. Collins, Colorado 80523",{"id":526,"sortIndex":111,"affiliation":527,"properties":24},"976aab4a-9412-4a3a-9ff2-6d28f25bc1e2",{"id":528,"createTime":529,"updateTime":529,"relativeEntities":530,"slug":531,"properties":532,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"4f04da83-a7e6-4aba-be5e-94a865695d87","2024-09-18T04:06:00.138+00:00",[],"Department-of-Veterinary-Pathobiology-College-of-Veterinary-Medicine-The-Ohio-State-University-Columbus-Ohio-43210",{"title":533},{"EN":534},"Department of Veterinary Pathobiology College of Veterinary Medicine The Ohio State University Columbus, Ohio 43210",{"openalex":536,"title":538},{"VOID":537},"A5056012463",{"EN":539},"M. G. Weiser",{"url":24,"publisher":541,"properties":571},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":542,"slug":10,"properties":543,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":549,"manageAffiliations":550,"indexDatabases":551,"url":105,"thumbnailPath":24,"statistic":566,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":544,"issn":545,"introduce":546,"eissn":547,"title":548},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[552,559],{"id":67,"indexDatabase":553,"url":80,"indexYears":81,"academicFieldIds":558,"indexDatabaseRanking":85},{"id":69,"createTime":70,"updateTime":71,"relativeEntities":554,"label":555,"description":556,"key":77,"publicationTags":557,"standard":24},[],{"EN":74,"VI":74},{"EN":74,"VI":76},[79],[83,84],{"id":87,"indexDatabase":560,"url":102,"indexYears":24,"academicFieldIds":565,"indexDatabaseRanking":24},{"id":89,"createTime":90,"updateTime":91,"relativeEntities":561,"label":562,"description":563,"key":98,"publicationTags":564,"standard":24},[],{"EN":94,"VI":94},{"VI":96,"EN":97},[100,101],[104],{"impactFactor":25,"impactFactorByYear":567,"i10Index":109,"i10IndexLast5Year":25,"totalPublication":53,"totalPublicationByYear":568,"totalCitation":112,"totalCitationByYear":569,"totalCitationPerPublication":121,"totalCitationPerPublicationByYear":570,"hindexLast5Year":109,"hindex":109},{"2012":108,"2019":108},{"1983":111,"1988":111,"1993":111,"1996":111,"2000":111,"2008":111,"2010":111,"2017":111},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"volume":572,"pages":573,"issue":575},{"VOID":125},{"VOID":574},"25-32",{"VOID":451},{"total":114,"publishYear":24,"statisticByYear":577},{"2022":111},"1983-04-01",1983,[581,584,587,590,593,596,599,602,605,608,611,614],{"id":24,"text":582,"url":24,"identifiers":583},"Koepke JA, 1982, Innovations in Hematology Instrumentation, Laboratory Perspectives, 1, 2",{},{"id":24,"text":585,"url":24,"identifiers":586},"10.1093\u002Fajcp\u002F52.6.679",{"doi":585},{"id":24,"text":588,"url":24,"identifiers":589},"10.1136\u002Fjcp.23.1.68",{"doi":588},{"id":24,"text":591,"url":24,"identifiers":592},"10.1093\u002Fajcp\u002F74.2.157",{"doi":591},{"id":24,"text":594,"url":24,"identifiers":595},"Weiser MG, 1982, Erythrocyte Volume Distribution in Clinically Normal Dogs, Cats, Horses and Dairy Cows, Am J Vet Res, 43, 163",{},{"id":24,"text":597,"url":24,"identifiers":598},"10.1177\u002F030098588302000405",{"doi":597},{"id":24,"text":600,"url":24,"identifiers":601},"10.1177\u002F030098588302000101",{"doi":600},{"id":24,"text":603,"url":24,"identifiers":604},"10.7326\u002F0003-4819-89-2-200",{"doi":603},{"id":24,"text":606,"url":24,"identifiers":607},"10.1056\u002FNEJM197203092861001",{"doi":606},{"id":24,"text":609,"url":24,"identifiers":610},"10.1093\u002Fajcp\u002F68.4.449",{"doi":609},{"id":24,"text":612,"url":24,"identifiers":613},"10.1093\u002Fajcp\u002F76.5.685",{"doi":612},{"id":24,"text":615,"url":24,"identifiers":616},"10.1203\u002F00006450-198002000-00013",{"doi":615},{"id":618,"createTime":619,"updateTime":620,"relativeEntities":621,"slug":622,"properties":623,"entityType":150,"verifyStatus":23,"verifyTime":619,"verifyNote":639,"syncStatus":23,"languages":640,"translateLanguages":641,"viewCount":25,"primaryUrl":642,"fullTextUrl":24,"authors":643,"publicationType":258,"publisherRelationship":716,"citationCount":119,"citationInfo":753,"publishDate":755,"publishYear":756,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":757,"isForceReanalyzing":348},"fe3584ca-eb1c-4d80-a279-2b8c5469c5e5","2024-09-21T03:54:34.089+00:00","2025-02-13T22:54:32.831+00:00",[],"Extranodal-%CE%B3%CE%B4-T-cell-lymphoma-in-a-dog-with-leishmaniasis",{"mag":624,"keywords":626,"openalex":627,"abstract":629,"title":632,"pm":635,"doi":637},{"VOID":625},"2014670846",{"VI":359},{"VOID":628},"W2014670846",{"EN":630,"VI":631},"\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> An 8‐year‐old intact male mongrel dog with alopecia and weight loss was referred to the Veterinary Faculty of Naples. The dog had pale mucous membranes, enlarged prescapular lymph nodes, and splenomegaly. Laboratory abnormalities included anemia, thrombocytopenia, and hyperglobulinemia. Bone marrow aspirate smears contained numerous \u003Cjats:italic>Leishmania\u003C\u002Fjats:italic> amastigotes and an immunofluorescent antibody titer was strongly positive (1:1280) for leishmaniasis. The dog was treated with a combination of meglumine antimoniate and allopurinol for 60 days and showed clinical improvement. Two months after the end of treatment the dog was again referred because of relapse of leishmaniasis and the presence of a firm subcutaneous mass on the medial right thigh. Based on cytologic examination of fine needle aspirates of the mass, a diagnosis of large‐cell lymphoma was made. Flow cytometry of tumor cells revealed γδ‐T‐cell lymphoma with a CD5+, CD3+, TCRγδ+, CD4−, CD8−, CD45RA+ immunophenotype. Using nested PCR, amastigotes were not detected in the neoplastic tissue. An association between leishmaniasis and hematopoietic tumors has been described rarely. γδ‐T cells may be involved in the host response to this parasite, and prolonged antigenic stimulation and chronic immunosuppression (typical of leishmaniasis) play a crucial role in the etiopathogenesis of T‐cell lymphoma.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Tóm tắt: \u003C\u002Fjats:bold> Một con chó đực hỗn hợp 8 tuổi không bị thiến, mắc chứng rụng lông và giảm cân đã được giới thiệu đến Khoa Thú y của Naples. Con chó có niêm mạc nhợt nhạt, hạch bạch huyết trước vai to lên và lách phì đại. Các bất thường trong xét nghiệm máu bao gồm thiếu máu, giảm tiểu cầu và tăng globulin huyết. Mẫu tủy xương cho thấy có nhiều thể amastigote của \u003Cjats:italic>Leishmania\u003C\u002Fjats:italic> và mức kháng thể huỳnh quang miễn dịch rất cao (1:1280) đối với bệnh leishmaniasis. Con chó đã được điều trị bằng sự kết hợp của meglumine antimoniate và allopurinol trong 60 ngày và đã cho thấy sự cải thiện lâm sàng. Hai tháng sau khi kết thúc điều trị, con chó lại được giới thiệu do tái phát bệnh leishmaniasis và sự hiện diện của một khối u dưới da chắc chắn ở đùi trong bên phải. Dựa trên kiểm tra tế bào học của các mẫu tế bào hút bằng kim nhỏ của khối u, một chẩn đoán về lymphôm tế bào lớn đã được đưa ra. Phân tích dòng tế bào khối u cho thấy lymphôm tế bào γδ với kiểu hình miễn dịch CD5+, CD3+, TCRγδ+, CD4−, CD8−, CD45RA+. Sử dụng PCR tổ hợp, không phát hiện được amastigote trong mô khối u. Mối liên hệ giữa bệnh leishmaniasis và các khối u huyết học đã được mô tả hiếm khi. Tế bào γδ có thể tham gia vào phản ứng của cơ thể đối với ký sinh trùng này, và sự kích thích kháng nguyên kéo dài và tình trạng ức chế miễn dịch mãn tính (đặc trưng của bệnh leishmaniasis) đóng vai trò quyết định trong sinh học bệnh của lymphôm tế bào T.\u003C\u002Fjats:p>",{"EN":633,"VI":634},"Extranodal γδ‐T‐cell lymphoma in a dog with leishmaniasis","U lymphôm tế bào γδ ngoại hạch ở một con chó mắc bệnh leishmaniasis",{"VOID":636},"18761522",{"VOID":638},"10.1111\u002Fj.1939-165x.2008.00048.x","Author affiliation is blank",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.2008.00048.x",[644,655,666,675,696,707],{"id":645,"sortIndex":198,"researcher":24,"roles":646,"affiliations":647,"properties":648},"6719896a-3493-4418-a97e-b074a5ce021a",[],[],{"openalex":649,"orcid":651,"title":653},{"VOID":650},"A5025839671",{"VOID":652},"https:\u002F\u002Forcid.org\u002F0000-0003-0949-6818",{"EN":654},"Luigi Gradoni",{"id":656,"sortIndex":161,"researcher":24,"roles":657,"affiliations":658,"properties":659},"a47b7412-1e00-4ed0-9af4-a5cecfa87d84",[],[],{"openalex":660,"orcid":662,"title":664},{"VOID":661},"A5013867773",{"VOID":663},"https:\u002F\u002Forcid.org\u002F0000-0001-6307-3395",{"EN":665},"Brunella Restucci",{"id":667,"sortIndex":111,"researcher":24,"roles":668,"affiliations":669,"properties":670},"972c355f-b754-4260-aaf8-96e345efecae",[],[],{"openalex":671,"title":673},{"VOID":672},"A5037887749",{"EN":674},"A. Pagano",{"id":676,"sortIndex":25,"researcher":24,"roles":677,"affiliations":678,"properties":689},"120043a1-af07-4e91-98ed-d3199475eddc",[],[679],{"id":680,"sortIndex":25,"affiliation":681,"properties":24},"31f936f5-3e41-457a-bff3-7ca87b7ea37c",{"id":682,"createTime":683,"updateTime":683,"relativeEntities":684,"slug":685,"properties":686,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"96c14711-4472-4049-b496-65547d7f0ae4","2024-09-21T03:54:34.107+00:00",[],"Dipartimento-di-Scienze-Cliniche-Veterinarie-Facolt%C3%A0-di-Medicina-Veterinaria-Universit%C3%A0-di-Napoli-Federico-II-Napoli-Italy-",{"title":687},{"EN":688},"Dipartimento di Scienze Cliniche Veterinarie, Facoltà di Medicina Veterinaria-Università di Napoli Federico II, Napoli, Italy.",{"openalex":690,"orcid":692,"title":694},{"VOID":691},"A5041191271",{"VOID":693},"https:\u002F\u002Forcid.org\u002F0000-0003-0276-5181",{"EN":695},"Valentina Foglia Manzillo",{"id":697,"sortIndex":244,"researcher":24,"roles":698,"affiliations":699,"properties":700},"0ecda501-e8e3-449a-9c5b-50fd1092099b",[],[],{"openalex":701,"orcid":703,"title":705},{"VOID":702},"A5002191079",{"VOID":704},"https:\u002F\u002Forcid.org\u002F0000-0002-2949-5479",{"EN":706},"Gætano Oliva",{"id":708,"sortIndex":108,"researcher":24,"roles":709,"affiliations":710,"properties":711},"22f49971-86f7-4295-bc7c-b86c714f5755",[],[],{"openalex":712,"title":714},{"VOID":713},"A5004242889",{"EN":715},"Roberta Guglielmino",{"url":24,"publisher":717,"properties":747},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":718,"slug":10,"properties":719,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":725,"manageAffiliations":726,"indexDatabases":727,"url":105,"thumbnailPath":24,"statistic":742,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":720,"issn":721,"introduce":722,"eissn":723,"title":724},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[728,735],{"id":67,"indexDatabase":729,"url":80,"indexYears":81,"academicFieldIds":734,"indexDatabaseRanking":85},{"id":69,"createTime":70,"updateTime":71,"relativeEntities":730,"label":731,"description":732,"key":77,"publicationTags":733,"standard":24},[],{"EN":74,"VI":74},{"EN":74,"VI":76},[79],[83,84],{"id":87,"indexDatabase":736,"url":102,"indexYears":24,"academicFieldIds":741,"indexDatabaseRanking":24},{"id":89,"createTime":90,"updateTime":91,"relativeEntities":737,"label":738,"description":739,"key":98,"publicationTags":740,"standard":24},[],{"EN":94,"VI":94},{"VI":96,"EN":97},[100,101],[104],{"impactFactor":25,"impactFactorByYear":743,"i10Index":109,"i10IndexLast5Year":25,"totalPublication":53,"totalPublicationByYear":744,"totalCitation":112,"totalCitationByYear":745,"totalCitationPerPublication":121,"totalCitationPerPublicationByYear":746,"hindexLast5Year":109,"hindex":109},{"2012":108,"2019":108},{"1983":111,"1988":111,"1993":111,"1996":111,"2000":111,"2008":111,"2010":111,"2017":111},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"volume":748,"pages":750,"issue":752},{"VOID":749},"37",{"VOID":751},"298-301",{"VOID":296},{"total":119,"publishYear":24,"statisticByYear":754},{"2012":108,"2013":198,"2014":111,"2015":111,"2016":108,"2017":111,"2018":111,"2019":198,"2020":108,"2021":161,"2022":198,"2024":108},"2008-09-01",2008,[758,761,764,767,770,773,776,779,782,785,788,791,794,797,800,803,806,809,813,816,819,823],{"id":24,"text":759,"url":24,"identifiers":760},"10.1136\u002Fvr.141.21.539",{"doi":759},{"id":24,"text":762,"url":24,"identifiers":763},"Evans DA., 1987, In Vitro Methods for Parasite Cultivation, 52",{},{"id":24,"text":765,"url":24,"identifiers":766},"10.1128\u002FJCM.44.4.1318-1322.2006",{"doi":765},{"id":24,"text":768,"url":24,"identifiers":769},"Lanotte G, 1979, Ecologie des leishmanioses dans le sud de France. Les formes evolutives de la leishmaniose viscerale canine. Ecology of leishmaniases in South France. [The evolutive forms of visceral canine leishmaniasis], Ann Parasitol Hum Comp, 54, 277",{},{"id":24,"text":771,"url":24,"identifiers":772},"10.1111\u002Fj.1365-3024.1991.tb00550.x",{"doi":771},{"id":24,"text":774,"url":24,"identifiers":775},"Berrahal F, 1996, Canine leishmaniasis, identification of asymptomatic carriers by polymerase chain reaction and immunoblotting, 55, 273",{},{"id":24,"text":777,"url":24,"identifiers":778},"MacEwen EG, 1996, Small Animal Clinical Oncology, 451",{},{"id":24,"text":780,"url":24,"identifiers":781},"Moore PF, 2000, Schalm's Veterinary Hematology, 247",{},{"id":24,"text":783,"url":24,"identifiers":784},"10.1016\u002FS0165-2427(99)00051-3",{"doi":783},{"id":24,"text":786,"url":24,"identifiers":787},"10.1354\u002Fvp.37-6-637",{"doi":786},{"id":24,"text":789,"url":24,"identifiers":790},"10.1354\u002Fvp.40-5-556",{"doi":789},{"id":24,"text":792,"url":24,"identifiers":793},"Moore PF, 1998, Advances in Veterinary Dermatology, 77",{},{"id":24,"text":795,"url":24,"identifiers":796},"Moore PF, 1994, Canine cutaneous epitheliotropic lymphoma (mycosis fungoides) is a proliferative disorder of CD8+ T‐cell, Am J Pathol, 144, 421",{},{"id":24,"text":798,"url":24,"identifiers":799},"DeWolf‐Peeters C, 2000, γδ T‐cell lymphoma, a homogeneous entity?, 36, 294",{},{"id":24,"text":801,"url":24,"identifiers":802},"Salhany KE, 1998, Subcutaneous panniculitis‐like‐ T‐cell lymphoma, clinicopathologic, immuno-phenotypic and genotypic analysis of alpha\u002Fbeta and gamma\u002Fdelta subtypes, 22, 881",{},{"id":24,"text":804,"url":24,"identifiers":805},"10.1038\u002F373255a0",{"doi":804},{"id":24,"text":807,"url":24,"identifiers":808},"10.1038\u002F339544a0",{"doi":807},{"id":24,"text":810,"url":24,"identifiers":811},"Russo DM, 1993, Antigen‐reactive γδ T‐cells in human leishmaniasis, J Immunol, 151, 3712, 10.4049\u002Fjimmunol.151.7.3712",{"doi":812},"10.4049\u002Fjimmunol.151.7.3712",{"id":24,"text":814,"url":24,"identifiers":815},"10.1016\u002F0923-2494(91)90007-6",{"doi":814},{"id":24,"text":817,"url":24,"identifiers":818},"10.1016\u002FS0065-308X(04)57001-X",{"doi":817},{"id":24,"text":820,"url":24,"identifiers":821},"Rosat JP, 1995, Expansion of γδ T‐cells in BALB\u002Fc mice infected with leishmania major is dependent upon Th2‐type CD4+ T cells, Infect Immun, 63, 3000, 10.1128\u002Fiai.63.8.3000-3004.1995",{"doi":822},"10.1128\u002Fiai.63.8.3000-3004.1995",{"id":24,"text":824,"url":24,"identifiers":825},"10.1136\u002Fvr.158.20.690",{"doi":824},{"id":827,"createTime":828,"updateTime":829,"relativeEntities":830,"slug":831,"properties":832,"entityType":150,"verifyStatus":151,"verifyTime":828,"verifyNote":152,"syncStatus":23,"languages":848,"translateLanguages":849,"viewCount":25,"primaryUrl":850,"fullTextUrl":24,"authors":851,"publicationType":258,"publisherRelationship":892,"citationCount":117,"citationInfo":930,"publishDate":932,"publishYear":933,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":934,"isForceReanalyzing":348},"b7c95885-29da-41a1-b80c-3ea487bf9d76","2024-09-18T04:06:00.072+00:00","2025-02-13T22:53:36.215+00:00",[],"Automated-Differential-Leukocyte-Count-in-Horses-Cattle-and-Cats-Using-the-Technicon-H-1E-Hematology-System",{"mag":833,"keywords":835,"openalex":836,"abstract":838,"title":841,"pm":844,"doi":846},{"VOID":834},"2121787596",{"VI":359},{"VOID":837},"W2121787596",{"EN":839,"VI":840},"\u003Cjats:p>The differential leukocyte counts performed by an automated hematology analyzer, the Technicon H‐1E Hematology System, and traditional microscopic method (M‐Diff) from blood samples of 129 horses, 40 cattle, and 140 cats were compared. The comparison was repeated after selected subsets of data were created by deleting samples with certain patterns suggesting error with the automated differential cell count (A‐Diff). The two methods had good comparison of results for neutrophils and lymphocytes in all three species. Results for equine monocytes correlated moderately well between the two methods and the correlation improved in the selected data set. Monocyte results did not compare well for the bovine and feline samples. The A‐Diff for feline eosinophils was inaccurate. The A‐Diff may be accurate for bovine and equine eosinophils but too few examples of eosinophilia were present in the sample set to prove this. Basophils were too rarely seen in cattle and horses to validate A‐Diff accuracy, but basophilia identified by the M‐Diff in a cat was not identified by the A‐Diff.\u003C\u002Fjats:p>","\u003Cjats:p>Các thông số bạch cầu phân biệt được thực hiện bằng máy phân tích huyết học tự động, Hệ thống huyết học Technicon H‐1E, và phương pháp kính hiển vi truyền thống (M‐Diff) từ mẫu máu của 129 con ngựa, 40 con gia súc và 140 con mèo đã được so sánh. Sự so sánh đã được thực hiện lại sau khi tạo ra các tập dữ liệu chọn lọc bằng cách xóa các mẫu có những biểu hiện cho thấy có lỗi trong việc đếm tế bào phân biệt tự động (A‐Diff). Hai phương pháp có sự so sánh tốt về kết quả đối với bạch cầu trung tính và lymphocyte ở cả ba loài. Kết quả cho bạch cầu đơn nhân ngựa có sự tương quan vừa đủ giữa hai phương pháp và sự tương quan được cải thiện trong tập dữ liệu chọn lọc. Kết quả của bạch cầu đơn nhân không có sự so sánh tốt đối với mẫu gia súc và mèo. Kết quả A‐Diff đối với bạch cầu ái toan mèo là không chính xác. A‐Diff có thể chính xác đối với bạch cầu ái toan ở gia súc và ngựa nhưng có quá ít mẫu bạch cầu ái toan trong tập mẫu để chứng minh điều này. Bạch cầu bazophil hiếm khi được thấy ở gia súc và ngựa đủ để xác minh độ chính xác của A‐Diff, nhưng bạch cầu bazophil được xác định bởi M‐Diff trong một con mèo đã không được A‐Diff phát hiện.\u003C\u002Fjats:p>",{"EN":842,"VI":843},"Automated Differential Leukocyte Count in Horses, Cattle, and Cats Using the Technicon H‐1E Hematology System","Đếm bạch cầu phân biệt tự động ở ngựa, gia súc và mèo sử dụng Hệ thống huyết học Technicon H‐1E",{"VOID":845},"12660982",{"VOID":847},"10.1111\u002Fj.1939-165x.1996.tb00960.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.1996.tb00960.x",[852,871],{"id":853,"sortIndex":111,"researcher":24,"roles":854,"affiliations":855,"properties":866},"07ba34d2-f067-4f83-9006-609d0ff65a42",[],[856],{"id":857,"sortIndex":25,"affiliation":858,"properties":24},"87f057e4-0d0d-49e4-9e04-17e679d4a9ee",{"id":859,"createTime":860,"updateTime":860,"relativeEntities":861,"slug":862,"properties":863,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"31c42ab5-f4bb-4271-89af-8a75a41fab1d","2024-09-18T04:06:00.097+00:00",[],"Veterinary-Medical-Complex-Michigan-State-University-East-Lansing-Michigan-48824-1314",{"title":864},{"EN":865},"Veterinary Medical Complex, Michigan State University, East Lansing, Michigan 48824-1314",{"openalex":867,"title":869},{"VOID":868},"A5037688143",{"EN":870},"David Korcal",{"id":872,"sortIndex":25,"researcher":24,"roles":873,"affiliations":874,"properties":885},"71433002-d32d-4a31-b833-35798d776324",[],[875],{"id":876,"sortIndex":25,"affiliation":877,"properties":24},"75db8a3f-8552-4cf6-bff9-3ef8660c2037",{"id":878,"createTime":879,"updateTime":879,"relativeEntities":880,"slug":881,"properties":882,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"328f576d-4e45-402f-b339-a13c54e6aa2e","2024-09-18T04:06:00.087+00:00",[],"Veterinary-Medical-Complex-Michigan-State-University-East-Lansing-MI-48824-1314-",{"title":883},{"EN":884},"Veterinary Medical Complex, Michigan State University, East Lansing, MI 48824-1314.",{"openalex":886,"orcid":888,"title":890},{"VOID":887},"A5061051950",{"VOID":889},"https:\u002F\u002Forcid.org\u002F0000-0003-4066-7662",{"EN":891},"Harold Tvedten",{"url":24,"publisher":893,"properties":923},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":894,"slug":10,"properties":895,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":901,"manageAffiliations":902,"indexDatabases":903,"url":105,"thumbnailPath":24,"statistic":918,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":896,"issn":897,"introduce":898,"eissn":899,"title":900},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[904,911],{"id":67,"indexDatabase":905,"url":80,"indexYears":81,"academicFieldIds":910,"indexDatabaseRanking":85},{"id":69,"createTime":70,"updateTime":71,"relativeEntities":906,"label":907,"description":908,"key":77,"publicationTags":909,"standard":24},[],{"EN":74,"VI":74},{"EN":74,"VI":76},[79],[83,84],{"id":87,"indexDatabase":912,"url":102,"indexYears":24,"academicFieldIds":917,"indexDatabaseRanking":24},{"id":89,"createTime":90,"updateTime":91,"relativeEntities":913,"label":914,"description":915,"key":98,"publicationTags":916,"standard":24},[],{"EN":94,"VI":94},{"VI":96,"EN":97},[100,101],[104],{"impactFactor":25,"impactFactorByYear":919,"i10Index":109,"i10IndexLast5Year":25,"totalPublication":53,"totalPublicationByYear":920,"totalCitation":112,"totalCitationByYear":921,"totalCitationPerPublication":121,"totalCitationPerPublicationByYear":922,"hindexLast5Year":109,"hindex":109},{"2012":108,"2019":108},{"1983":111,"1988":111,"1993":111,"1996":111,"2000":111,"2008":111,"2010":111,"2017":111},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"volume":924,"pages":926,"issue":928},{"VOID":925},"25",{"VOID":927},"14-22",{"VOID":929},"1",{"total":117,"publishYear":24,"statisticByYear":931},{"2012":108,"2013":111,"2014":111,"2015":111,"2018":111,"2019":111,"2020":111,"2021":108,"2022":111,"2024":111},"1996-03-01",1996,[935,938,941,944,947,950],{"id":24,"text":936,"url":24,"identifiers":937},"10.1111\u002Fj.1939-165X.1994.tb00686.x",{"doi":936},{"id":24,"text":939,"url":24,"identifiers":940},"10.1093\u002Fajcp\u002F91.5.563",{"doi":939},{"id":24,"text":942,"url":24,"identifiers":943},"Wenz B., 1987, The H*1 Hematology Analyzer. Its Performance Characteristics and Value in the Diagnosis of Infectious Disease, Arch Pathol Lab Med, 111, 521",{},{"id":24,"text":945,"url":24,"identifiers":946},"10.1093\u002Fajcp\u002F95.3.381",{"doi":945},{"id":24,"text":948,"url":24,"identifiers":949},"10.1093\u002Fclinchem\u002F19.1.49",{"doi":948},{"id":24,"text":951,"url":24,"identifiers":952},"10.1093\u002Flabmed\u002F11.6.371",{"doi":951},{"id":954,"createTime":955,"updateTime":956,"relativeEntities":957,"slug":958,"properties":959,"entityType":150,"verifyStatus":151,"verifyTime":955,"verifyNote":152,"syncStatus":23,"languages":975,"translateLanguages":976,"viewCount":25,"primaryUrl":977,"fullTextUrl":24,"authors":978,"publicationType":258,"publisherRelationship":1018,"citationCount":1056,"citationInfo":1057,"publishDate":1059,"publishYear":1060,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1061,"isForceReanalyzing":348},"4436f9e6-f25a-4c8c-8dfe-32dc63d26340","2024-11-25T16:55:58.253+00:00","2025-02-13T22:52:37.387+00:00",[],"Errors-in-basophil-enumeration-with-3-veterinary-hematology-systems-and-observations-on-occurrence-of-basophils-in-dogs",{"mag":960,"keywords":962,"openalex":963,"abstract":965,"title":968,"pm":971,"doi":973},{"VOID":961},"2092607372",{"VI":359},{"VOID":964},"W2092607372",{"EN":966,"VI":967},"\u003Cjats:sec>\u003Cjats:title>Background\u003C\u002Fjats:title>\u003Cjats:p>Most automated hematology analyzers cannot detect canine or feline basophils. However, many veterinary laboratories continue to report basophils as part of the automated 5‐part differential leukocyte count for dogs and cats.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Objectives\u003C\u002Fjats:title>\u003Cjats:p>The study objectives were to evaluate the performance of the \u003Cjats:styled-content style=\"fixed-case\">S\u003C\u002Fjats:styled-content>ysmex \u003Cjats:styled-content style=\"fixed-case\">XT\u003C\u002Fjats:styled-content>‐2000i\u003Cjats:styled-content style=\"fixed-case\">V\u003C\u002Fjats:styled-content>, \u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia 2120, and \u003Cjats:styled-content style=\"fixed-case\">CELL\u003C\u002Fjats:styled-content>‐\u003Cjats:styled-content style=\"fixed-case\">DYN\u003C\u002Fjats:styled-content> 3500 hematology analyzers in detecting basophils using blood from dogs, cats, and rabbits with basophilia and to investigate the concurrence of basophilia and other hematologic changes, sex, and breed in dogs.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods\u003C\u002Fjats:title>\u003Cjats:p>One or more of the 3 hematology analyzers was used to analyze 11 canine blood samples with prominent basophilia (≥ 5%) based on a manual differential count. In addition, samples from 2 cats and 4 rabbits with basophilia were analyzed with the \u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia 2120. Leukocyte cytograms were inspected for the likely location of basophil cell clusters. In a retrospective study of canine patients, reports of hematologic results that included a manual leukocyte differential count were identified using the laboratory information system and examined for the occurrence of basophilia and other hematologic changes, sex, and breed of the dogs.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>Canine basophils were not detected by the \u003Cjats:styled-content style=\"fixed-case\">S\u003C\u002Fjats:styled-content>ysmex \u003Cjats:styled-content style=\"fixed-case\">XT\u003C\u002Fjats:styled-content>‐2000i\u003Cjats:styled-content style=\"fixed-case\">V\u003C\u002Fjats:styled-content> or \u003Cjats:styled-content style=\"fixed-case\">CELL\u003C\u002Fjats:styled-content>‐\u003Cjats:styled-content style=\"fixed-case\">DYN\u003C\u002Fjats:styled-content> 3500 analyzers, and neither canine nor feline basophils were detected by the \u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia 2120. The \u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia was able to detect basophils in rabbits. On the \u003Cjats:styled-content style=\"fixed-case\">S\u003C\u002Fjats:styled-content>ysmex cytogram canine basophils were found slightly above or together with neutrophils. On the \u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia \u003Cjats:styled-content style=\"fixed-case\">P\u003C\u002Fjats:styled-content>erox cytogram canine basophils were located in upper part of the lymphocyte box and in the area of large unstained cells (\u003Cjats:styled-content style=\"fixed-case\">LUC\u003C\u002Fjats:styled-content>). Dogs with marked basophilia often had concurrent eosinophilia, and basophilia may be found more frequently in \u003Cjats:styled-content style=\"fixed-case\">R\u003C\u002Fjats:styled-content>ottweiler dogs than in other breeds. In 5 dogs with marked basophilia and without eosinophilia, marked thrombocytosis and anemia were noted.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>Canine basophils were not detected by these automated hematology analyzers, and careful analysis of instrument graphical displays or increased \u003Cjats:styled-content style=\"fixed-case\">LUC\u003C\u002Fjats:styled-content> (\u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia) may guide the need to examine a blood smear for basophils.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>","\u003Cjats:sec>\u003Cjats:title>Nền tảng\u003C\u002Fjats:title>\u003Cjats:p>Hầu hết các máy phân tích huyết học tự động không thể phát hiện bạch cầu basophil ở chó hoặc mèo. Tuy nhiên, nhiều phòng thí nghiệm thú y vẫn báo cáo bạch cầu basophil như một phần của tổng số bạch cầu phân loại tự động 5 phần cho chó và mèo.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Mục tiêu\u003C\u002Fjats:title>\u003Cjats:p>Mục tiêu của nghiên cứu là đánh giá hiệu suất của máy phân tích huyết học \u003Cjats:styled-content style=\"fixed-case\">S\u003C\u002Fjats:styled-content>ysmex \u003Cjats:styled-content style=\"fixed-case\">XT\u003C\u002Fjats:styled-content>‐2000i\u003Cjats:styled-content style=\"fixed-case\">V\u003C\u002Fjats:styled-content>, \u003Cjats:styled-content style=\"fixed-case\">A\u003C\u002Fjats:styled-content>dvia 2120, và \u003Cjats:styled-content style=\"fixed-case\">CELL\u003C\u002Fjats:styled-content>‐\u003Cjats:styled-content style=\"fixed-case\">DYN\u003C\u002Fjats:styled-content> 3500 trong việc phát hiện bạch cầu basophil sử dụng máu từ chó, mèo và thỏ có basophilia, và điều tra sự đồng thời của basophilia và các thay đổi huyết học khác, giới tính cũng như giống loài ở chó.",{"EN":969,"VI":970},"Errors in basophil enumeration with 3 veterinary hematology systems and observations on occurrence of basophils in dogs","Lỗi trong việc đếm số lượng bạch cầu basophil với 3 hệ thống huyết học thú y và quan sát về sự xuất hiện của bạch cầu basophil ở chó",{"VOID":972},"22092582",{"VOID":974},"10.1111\u002Fj.1939-165x.2011.00353.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.2011.00353.x",[979,997],{"id":980,"sortIndex":111,"researcher":24,"roles":981,"affiliations":982,"properties":993},"d82daa1f-e9ce-4884-ae06-ceca0cbef941",[],[983],{"id":984,"sortIndex":25,"affiliation":985,"properties":24},"e141d6ff-1c6f-4525-9d99-fbe37bf2d589",{"id":986,"createTime":987,"updateTime":987,"relativeEntities":988,"slug":989,"properties":990,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"8ae9b17d-bb3f-4039-8fb5-93ea436fdc1b","2025-12-12T09:20:30.110+00:00",[],"Department-of-Clinical-Sciences-Swedish-University-of-Agricultural-Sciences-Uppsala-Sweden",{"title":991},{"EN":992},"Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden",{"openalex":994,"orcid":995,"title":996},{"VOID":887},{"VOID":889},{"EN":891},{"id":998,"sortIndex":25,"researcher":24,"roles":999,"affiliations":1000,"properties":1011},"3d3d6c75-560a-4e1b-b5b9-270fb75a33a2",[],[1001],{"id":1002,"sortIndex":25,"affiliation":1003,"properties":24},"5e38f8b8-90cc-4326-81e9-2dd9f46af916",{"id":1004,"createTime":1005,"updateTime":1005,"relativeEntities":1006,"slug":1007,"properties":1008,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"799d0730-a0dc-48c0-87ee-a6f2840ccf6d","2024-11-25T16:55:58.265+00:00",[],"Clinical-Pathology-Laboratory-University-Animal-Hospital",{"title":1009},{"EN":1010},"Clinical Pathology Laboratory University Animal Hospital",{"openalex":1012,"orcid":1014,"title":1016},{"VOID":1013},"A5038914843",{"VOID":1015},"https:\u002F\u002Forcid.org\u002F0000-0002-9526-242X",{"EN":1017},"Inger Lilliehöök",{"url":24,"publisher":1019,"properties":1049},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1020,"slug":10,"properties":1021,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1027,"manageAffiliations":1028,"indexDatabases":1029,"url":105,"thumbnailPath":24,"statistic":1044,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1022,"issn":1023,"introduce":1024,"eissn":1025,"title":1026},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[1030,1037],{"id":67,"indexDatabase":1031,"url":80,"indexYears":81,"academicFieldIds":1036,"indexDatabaseRanking":85},{"id":69,"createTime":70,"updateTime":71,"relativeEntities":1032,"label":1033,"description":1034,"key":77,"publicationTags":1035,"standard":24},[],{"EN":74,"VI":74},{"EN":74,"VI":76},[79],[83,84],{"id":87,"indexDatabase":1038,"url":102,"indexYears":24,"academicFieldIds":1043,"indexDatabaseRanking":24},{"id":89,"createTime":90,"updateTime":91,"relativeEntities":1039,"label":1040,"description":1041,"key":98,"publicationTags":1042,"standard":24},[],{"EN":94,"VI":94},{"VI":96,"EN":97},[100,101],[104],{"impactFactor":25,"impactFactorByYear":1045,"i10Index":109,"i10IndexLast5Year":25,"totalPublication":53,"totalPublicationByYear":1046,"totalCitation":112,"totalCitationByYear":1047,"totalCitationPerPublication":121,"totalCitationPerPublicationByYear":1048,"hindexLast5Year":109,"hindex":109},{"2012":108,"2019":108},{"1983":111,"1988":111,"1993":111,"1996":111,"2000":111,"2008":111,"2010":111,"2017":111},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"volume":1050,"pages":1052,"issue":1054},{"VOID":1051},"40",{"VOID":1053},"450-458",{"VOID":1055},"4",48,{"total":1056,"publishYear":24,"statisticByYear":1058},{"2012":198,"2013":244,"2014":161,"2015":161,"2016":111,"2017":53,"2018":198,"2019":108,"2020":111,"2021":244,"2022":161,"2023":198,"2024":198},"2011-12-01",2011,[1062,1065,1068,1071,1074,1077,1080,1083,1086,1089,1092,1095,1098,1101,1103,1106,1109,1112,1115,1118,1121,1124,1127],{"id":24,"text":1063,"url":24,"identifiers":1064},"Schultze AE, 2010, Schalm's Veterinary Hematology, 321",{},{"id":24,"text":1066,"url":24,"identifiers":1067},"MacEwen EG, 1975, Treatment of basophilic leukemia in a dog, J Am Vet Med Assoc., 166, 376",{},{"id":24,"text":1069,"url":24,"identifiers":1070},"10.1111\u002Fj.1939-1676.1997.tb00079.x",{"doi":1069},{"id":24,"text":1072,"url":24,"identifiers":1073},"Favier RP, 2004, Essential thrombocythaemia in two dogs, Tijdschr Diergeneesk., 129, 360",{},{"id":24,"text":1075,"url":24,"identifiers":1076},"10.1292\u002Fjvms.68.1203",{"doi":1075},{"id":24,"text":1078,"url":24,"identifiers":1079},"10.1111\u002Fj.1939-1676.1987.tb01990.x",{"doi":1078},{"id":24,"text":1081,"url":24,"identifiers":1082},"Calvert CA, 1988, Pulmonary and disseminated eosinophilic granulomatosis in dogs, J Am Anim Hosp Assoc., 24, 311",{},{"id":24,"text":1084,"url":24,"identifiers":1085},"10.1111\u002Fj.1748-5827.1991.tb00863.x",{"doi":1084},{"id":24,"text":1087,"url":24,"identifiers":1088},"Glickman LT, 1984, Serological pattern of canine heartworm (Dirofilaria immitis) infection, Am J Vet Res., 45, 1178",{},{"id":24,"text":1090,"url":24,"identifiers":1091},"Rawlings CA, 1980, Eosinophilia and basophilia in Dirofilaria immitis and Dipetalonema reconditum infections, J Am Anim Hosp Assoc., 16, 699",{},{"id":24,"text":1093,"url":24,"identifiers":1094},"10.1024\u002F0036-7281.144.4.174",{"doi":1093},{"id":24,"text":1096,"url":24,"identifiers":1097},"10.1111\u002Fj.1748-5827.2008.00551.x",{"doi":1096},{"id":24,"text":1099,"url":24,"identifiers":1100},"10.1111\u002Fj.1939-165X.2009.00126.x",{"doi":1099},{"id":24,"text":936,"url":24,"identifiers":1102},{"doi":936},{"id":24,"text":1104,"url":24,"identifiers":1105},"10.1111\u002Fj.1939-165X.1996.tb00960.x",{"doi":1104},{"id":24,"text":1107,"url":24,"identifiers":1108},"10.1007\u002Fs00580-006-0602-x",{"doi":1107},{"id":24,"text":1110,"url":24,"identifiers":1111},"Allison RW, 2009, Appearance of granulated cells in blood films stained by automated aqueos versus methanolic Romanowsky methods, Vet Clin Pathol., 31, 99",{},{"id":24,"text":1113,"url":24,"identifiers":1114},"Matsumoto H, 1999, The technology of reagents in the automated hematology analyzer XE‐2100TM – red fluorescence reaction, Sysmex XT‐2000iV J Int., 9, 179",{},{"id":24,"text":1116,"url":24,"identifiers":1117},"Kabata J, 1991, Hematologic values of New Zealand white rabbits determined by automated flow cytometry, Lab Anim Sci., 41, 613",{},{"id":24,"text":1119,"url":24,"identifiers":1120},"10.1111\u002Fj.1748-5827.2000.tb03934.x",{"doi":1119},{"id":24,"text":1122,"url":24,"identifiers":1123},"Swedish Kennel Club. Registration data 2007. Available at:http:\u002F\u002Fwww.hundsport.se\u002Fring_rapport\u002Fskks_reg_statistik_mapp\u002Fpdf_filer_reg-statistik\u002Freg_statistik_2007.pdf. Accessed March 1 2008.",{},{"id":24,"text":1125,"url":24,"identifiers":1126},"10.1111\u002Fj.1939-1676.1989.tb03083.x",{"doi":1125},{"id":24,"text":1128,"url":24,"identifiers":1129},"10.1007\u002Fs00277-004-0877-4",{"doi":1128},{"id":1131,"createTime":1132,"updateTime":1133,"relativeEntities":1134,"slug":1135,"properties":1136,"entityType":150,"verifyStatus":151,"verifyTime":1132,"verifyNote":152,"syncStatus":23,"languages":1152,"translateLanguages":1153,"viewCount":25,"primaryUrl":1154,"fullTextUrl":24,"authors":1155,"publicationType":258,"publisherRelationship":1239,"citationCount":120,"citationInfo":1276,"publishDate":1281,"publishYear":1282,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1283,"isForceReanalyzing":348},"e696b2cf-7fda-4a2a-a1d4-fb4a30bfc7fb","2024-09-22T03:12:00.207+00:00","2025-02-13T22:51:41.192+00:00",[],"Hematologic-and-biochemical-reference-intervals-for-Norwegian-crossbreed-grower-pigs",{"mag":1137,"keywords":1139,"openalex":1140,"abstract":1142,"title":1145,"pm":1148,"doi":1150},{"VOID":1138},"1500728883",{"VI":359},{"VOID":1141},"W1500728883",{"EN":1143,"VI":1144},"\u003Cjats:p>\u003Cjats:bold>Background: \u003C\u002Fjats:bold> Hematologic and biochemical reference intervals depend on many factors, including environment and age. Reference intervals for Norwegian grower pigs are lacking, and previously published reference intervals for similar pigs from other countries are now outdated due to significant changes in management and breeding on the pig farms.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Objectives: \u003C\u002Fjats:bold> The aim of this study was to determine updated reference intervals for hematologic and biochemical analytes in healthy crossbred grower pigs, and to compare the results among 3 different farms.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Methods: \u003C\u002Fjats:bold> Blood samples were collected from 104 clinically healthy pigs of the most common Norwegian crossbreed (Landrace Yorkshire sow × Landrace Duroc boar). The pigs were 12–16 weeks old, weighed 30–50 kg, of both sexes, and lived on 3 farms in eastern Norway. Automated hematologic and biochemical analysis were performed using ADVIA 2120 and ADVIA 1650 analyzers.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Results: \u003C\u002Fjats:bold> Five samples were excluded because of hemolysis (1) or outliers (4). Reference intervals were calculated using parametric or nonparametric methods, depending on data distribution. Mean, median, minimum, and maximum values were tabulated.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Conclusions: \u003C\u002Fjats:bold> The reference intervals calculated in this study will be useful for the diagnosis and monitoring of disease in this widespread crossbreed pig. Compared with previously published reference values, reference intervals for total WBC count, creatine kinase and alanine aminotransferase activities, and albumin, bilirubin, and urea concentrations in this study differed notably.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Nền tảng: \u003C\u002Fjats:bold> Các khoảng tham chiếu huyết học và hóa sinh phụ thuộc vào nhiều yếu tố, bao gồm môi trường và độ tuổi. Các khoảng tham chiếu cho lợn giống lai Norwegian còn thiếu, và các khoảng tham chiếu đã công bố trước đây cho lợn tương tự từ các quốc gia khác hiện đã lỗi thời do những thay đổi đáng kể trong quản lý và chăn nuôi trên các trang trại lợn.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Mục tiêu: \u003C\u002Fjats:bold> Mục đích của nghiên cứu này là xác định các khoảng tham chiếu cập nhật cho các chất phân tích huyết học và hóa sinh ở lợn giống lai khỏe mạnh và so sánh kết quả ở 3 trang trại khác nhau.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Phương pháp: \u003C\u002Fjats:bold> Mẫu máu được thu thập từ 104 con lợn khỏe mạnh về lâm sàng thuộc giống lai phổ biến nhất của Norway (Lợn cái Landrace Yorkshire × Lợn đực Landrace Duroc). Các con lợn có độ tuổi từ 12–16 tuần, trọng lượng từ 30–50 kg, thuộc cả hai giới tính và sống ở 3 trang trại tại miền đông Norway. Phân tích huyết học và hóa sinh tự động được thực hiện bằng cách sử dụng các thiết bị phân tích ADVIA 2120 và ADVIA 1650.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Kết quả: \u003C\u002Fjats:bold> Năm mẫu đã bị loại trừ do hiện tượng tan máu (1) hoặc ngoại lệ (4). Các khoảng tham chiếu được tính toán sử dụng phương pháp tham số hoặc phi tham số, tùy thuộc vào phân phối dữ liệu. Giá trị trung bình, trung vị, giá trị tối thiểu và tối đa đã được lập bảng.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Kết luận: \u003C\u002Fjats:bold> Các khoảng tham chiếu được tính toán trong nghiên cứu này sẽ hữu ích cho việc chẩn đoán và theo dõi bệnh ở giống lợn lai phổ biến này. So với các giá trị tham khảo đã công bố trước đây, các khoảng tham chiếu cho tổng số bạch cầu, hoạt động của creatine kinase và alanine aminotransferase, cùng nồng độ albumin, bilirubin và ure trong nghiên cứu này khác biệt đáng kể.",{"EN":1146,"VI":1147},"Hematologic and biochemical reference intervals for Norwegian crossbreed grower pigs","Khoảng tham chiếu huyết học và hóa sinh cho lợn giống lai Norwegian",{"VOID":1149},"20051064",{"VOID":1151},"10.1111\u002Fj.1939-165x.2009.00199.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.2009.00199.x",[1156,1177,1192,1209,1224],{"id":1157,"sortIndex":198,"researcher":24,"roles":1158,"affiliations":1159,"properties":1170},"a7d21361-0ec4-4641-aafe-20dc06c959c9",[],[1160],{"id":1161,"sortIndex":25,"affiliation":1162,"properties":24},"7c6be357-a96a-40f2-af91-39c3d08bc3fb",{"id":1163,"createTime":1164,"updateTime":1164,"relativeEntities":1165,"slug":1166,"properties":1167,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"2e93828e-2bbc-42a3-8594-43cc4580689c","2024-09-22T03:12:00.229+00:00",[],"Departments-of-1Production-Animal-Sciences-and-2Basic-Sciences-and-Aquatic-Medicine-Norwegian-School-of-Veterinary-Science-Oslo-Norway",{"title":1168},{"EN":1169},"Departments of 1Production Animal Sciences and 2Basic Sciences and Aquatic Medicine, Norwegian School of Veterinary Science, Oslo, Norway",{"openalex":1171,"orcid":1173,"title":1175},{"VOID":1172},"A5043388023",{"VOID":1174},"https:\u002F\u002Forcid.org\u002F0000-0001-7014-8949",{"EN":1176},"S. I. Thoresen",{"id":1178,"sortIndex":161,"researcher":24,"roles":1179,"affiliations":1180,"properties":1187},"3cbf0aa4-f1b8-4a7c-861d-813cfa71d022",[],[1181],{"id":1182,"sortIndex":25,"affiliation":1183,"properties":24},"30f0f921-e689-40bf-84fa-16c4204562c8",{"id":1163,"createTime":1164,"updateTime":1164,"relativeEntities":1184,"slug":1166,"properties":1185,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1186},{"EN":1169},{"openalex":1188,"title":1190},{"VOID":1189},"A5024103678",{"EN":1191},"Tore Framstad",{"id":1193,"sortIndex":25,"researcher":24,"roles":1194,"affiliations":1195,"properties":1202},"66552f87-f271-455a-98ee-c976e1640349",[],[1196],{"id":1197,"sortIndex":25,"affiliation":1198,"properties":24},"64ad13ce-4659-4eab-abc0-b0f17b879f99",{"id":1163,"createTime":1164,"updateTime":1164,"relativeEntities":1199,"slug":1166,"properties":1200,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1201},{"EN":1169},{"openalex":1203,"orcid":1205,"title":1207},{"VOID":1204},"A5080792039",{"VOID":1206},"https:\u002F\u002Forcid.org\u002F0000-0001-5138-775X",{"EN":1208},"Thea Blystad Klem",{"id":1210,"sortIndex":108,"researcher":24,"roles":1211,"affiliations":1212,"properties":1219},"ead54b81-2170-4013-ab2f-7304b9cb69c0",[],[1213],{"id":1214,"sortIndex":25,"affiliation":1215,"properties":24},"ec9790ec-4a17-49d1-be7d-a46e5fb694a5",{"id":1163,"createTime":1164,"updateTime":1164,"relativeEntities":1216,"slug":1166,"properties":1217,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1218},{"EN":1169},{"openalex":1220,"title":1222},{"VOID":1221},"A5006735937",{"EN":1223},"Hanne Morberg",{"id":1225,"sortIndex":111,"researcher":24,"roles":1226,"affiliations":1227,"properties":1234},"66887fac-337d-4d12-987a-51ec7050cb8f",[],[1228],{"id":1229,"sortIndex":25,"affiliation":1230,"properties":24},"e4cf58d4-7197-424c-ab7c-8560f3501a21",{"id":1163,"createTime":1164,"updateTime":1164,"relativeEntities":1231,"slug":1166,"properties":1232,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1233},{"EN":1169},{"openalex":1235,"title":1237},{"VOID":1236},"A5003548304",{"EN":1238},"Elisabeth Bleken",{"url":24,"publisher":1240,"properties":1270},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1241,"slug":10,"properties":1242,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1248,"manageAffiliations":1249,"indexDatabases":1250,"url":105,"thumbnailPath":24,"statistic":1265,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1243,"issn":1244,"introduce":1245,"eissn":1246,"title":1247},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[1251,1258],{"id":67,"indexDatabase":1252,"url":80,"indexYears":81,"academicFieldIds":1257,"indexDatabaseRanking":85},{"id":69,"createTime":70,"updateTime":71,"relativeEntities":1253,"label":1254,"description":1255,"key":77,"publicationTags":1256,"standard":24},[],{"EN":74,"VI":74},{"EN":74,"VI":76},[79],[83,84],{"id":87,"indexDatabase":1259,"url":102,"indexYears":24,"academicFieldIds":1264,"indexDatabaseRanking":24},{"id":89,"createTime":90,"updateTime":91,"relativeEntities":1260,"label":1261,"description":1262,"key":98,"publicationTags":1263,"standard":24},[],{"EN":94,"VI":94},{"VI":96,"EN":97},[100,101],[104],{"impactFactor":25,"impactFactorByYear":1266,"i10Index":109,"i10IndexLast5Year":25,"totalPublication":53,"totalPublicationByYear":1267,"totalCitation":112,"totalCitationByYear":1268,"totalCitationPerPublication":121,"totalCitationPerPublicationByYear":1269,"hindexLast5Year":109,"hindex":109},{"2012":108,"2019":108},{"1983":111,"1988":111,"1993":111,"1996":111,"2000":111,"2008":111,"2010":111,"2017":111},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"1983":114,"1988":115,"1993":116,"1996":117,"2000":118,"2008":119,"2010":120,"2017":63},{"volume":1271,"pages":1273,"issue":1275},{"VOID":1272},"39",{"VOID":1274},"221-226",{"VOID":451},{"total":120,"publishYear":24,"statisticByYear":1277},{"2012":108,"2013":111,"2014":244,"2015":63,"2016":108,"2017":198,"2018":63,"2019":1278,"2020":1278,"2021":1279,"2022":1280,"2023":1278,"2024":53},9,11,13,"2010-06-01",2010,[1284,1287,1290,1293,1296,1299,1303,1306,1309,1312,1315,1318,1321,1324,1327],{"id":24,"text":1285,"url":24,"identifiers":1286},"Dubreuil P, 1997, Biochemistry reference values for Quebeck lactating dairy cows, nursing sows, growing pigs and calves, Can J Vet Res, 61, 235",{},{"id":24,"text":1288,"url":24,"identifiers":1289},"10.1016\u002FS0007-1935(17)36632-0",{"doi":1288},{"id":24,"text":1291,"url":24,"identifiers":1292},"Friendship RM, 1992, Diseases of Swine, 3",{},{"id":24,"text":1294,"url":24,"identifiers":1295},"Dubreuil P, 1990, Effects of experimenters and different blood sampling procedures on blood metabolite values in growing pigs, Can J Vet Res, 54, 379",{},{"id":24,"text":1297,"url":24,"identifiers":1298},"Framstad T, 1991, Biochemical analysis of blood. Reference values for sows, Nor Vet Tidsskr, 103, 807",{},{"id":24,"text":1300,"url":24,"identifiers":1301},"Egeli AK, 1998, Clinical biochemistry, hematology and bodyweight in piglets, Acta Vet Scand, 39, 381, 10.1186\u002FBF03547786",{"doi":1302},"10.1186\u002FBF03547786",{"id":24,"text":1304,"url":24,"identifiers":1305},"Glawishnig E, 1977, Arbeitsverte in der Laboratoriumsdiagnostik beim Schwein [Reference intervals in laboratory diagnostics in pigs], Wien Tieraertzl Monatsschr, 64, 341",{},{"id":24,"text":1307,"url":24,"identifiers":1308},"Friendship RM, 1984, Hematology and biochemistry reference values for Ontario swine, Can J Comp Med, 48, 390",{},{"id":24,"text":1310,"url":24,"identifiers":1311},"Framstad T, 1988, Blood specimen collection in pigs, Nor Vet Tidsskr, 100, 265",{},{"id":24,"text":1313,"url":24,"identifiers":1314},"10.2307\u002F3001634",{"doi":1313},{"id":24,"text":1316,"url":24,"identifiers":1317},"Solberg HE, 1983, The theory of reference values. Part 5, J Clin Chem Clin Biochem, 21, 749",{},{"id":24,"text":1319,"url":24,"identifiers":1320},"10.1016\u002FB978-0-12-370491-7.00001-5",{"doi":1319},{"id":24,"text":1322,"url":24,"identifiers":1323},"Framstad T, 1989, Effect of storage, centrifugation and sodium heparinate on clinical chemical analysis of blood constituents from pigs, Nor Vet Tidsskr, 101, 237",{},{"id":24,"text":1325,"url":24,"identifiers":1326},"Reese DE, 1984, Serum chemical values of gestating and lactating swine, reference values, 45, 978",{},{"id":24,"text":1328,"url":24,"identifiers":1329},"McClellan RO, 1966, Swine in Biomedical Research, 597",{},{"id":1331,"createTime":1332,"updateTime":1333,"relativeEntities":1334,"slug":1335,"properties":1336,"entityType":150,"verifyStatus":151,"verifyTime":1332,"verifyNote":152,"syncStatus":23,"languages":1353,"translateLanguages":1354,"viewCount":25,"primaryUrl":1355,"fullTextUrl":24,"authors":1356,"publicationType":258,"publisherRelationship":1415,"citationCount":118,"citationInfo":1452,"publishDate":1460,"publishYear":1461,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1462,"isForceReanalyzing":348},"1c6478a4-3d3e-48c0-8b73-e34d3a614cbe","2024-09-28T15:01:22.898+00:00","2025-02-13T22:50:44.085+00:00",[],"Hematology-and-Plasma-Chemistry-Reference-Intervals-for-Cultured-Tilapia-i-Oreochromis-i-Hybrid-",{"mag":1337,"keywords":1339,"openalex":1341,"abstract":1343,"title":1346,"pm":1349,"doi":1351},{"VOID":1338},"2145010138",{"VI":1340},"Tilapia, huyết học, hóa học plasma, khoảng tham chiếu, nuôi trồng thủy sản",{"VOID":1342},"W2145010138",{"EN":1344,"VI":1345},"\u003Cjats:p>\u003Cjats:bold>Abstract:\u003C\u002Fjats:bold>Tilapia are a commonly aquacultured fish yet little is known about their normal physiology and response to disease. In this study we determined the results of complete hematologic (n = 40) and plasma biochemical profiles (n = 63) in production tilapia (\u003Cjats:italic>Oreochromis\u003C\u002Fjats:italic>hybrids). The fish were raised in recirculating systems with a high stocking density (120 g\u002FL), and were in the middle of a 15‐month production cycle. Blood was analyzed using standard techniques, and reference intervals were determined using nonparametric methods. Non‐production tilapia (n = 15) from low‐density tanks (4 g\u002FL) also were sampled; the clinical chemistry results were compared to reference intervals from the fish raised in high‐density tanks. Differences were noted in plasma protein, calcium and phosphorus concentrations, such that reference intervals for high‐density production tilapia were not applicable to fish raised under different environmental and management conditions.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Tóm tắt:\u003C\u002Fjats:bold>Cá Tilapia là loài cá thường được nuôi trồng trong ngành thủy sản, tuy nhiên vẫn còn ít thông tin về sinh lý bình thường và phản ứng của chúng đối với bệnh lý. Trong nghiên cứu này, chúng tôi đã xác định kết quả của hồ sơ huyết học hoàn chỉnh (n = 40) và hồ sơ sinh hóa plasma (n = 63) ở cá Tilapia được nuôi trồng (\u003Cjats:italic>Oreochromis\u003C\u002Fjats:italic> lai). Cá được nuôi trong các hệ thống tuần hoàn với mật độ nuôi cao (120 g\u002FL), và đang ở giữa chu trình sản xuất kéo dài 15 tháng. Máu đã được phân tích bằng các kỹ thuật chuẩn, và các khoảng tham chiếu đã được xác định bằng các phương pháp không tham số. Những cá Tilapia không nuôi sản phẩm (n = 15) từ các bể nuôi có mật độ thấp (4 g\u002FL) cũng đã được lấy mẫu; kết quả hóa sinh lâm sàng được so sánh với các khoảng tham chiếu từ cá nuôi ở bể có mật độ cao. Sự khác biệt đã được ghi nhận ở nồng độ protein plasma, canxi và photpho, do đó các khoảng tham chiếu cho cá Tilapia nuôi sản xuất với mật độ cao không áp dụng đối với cá nuôi trong các điều kiện môi trường và quản lý khác nhau.\u003C\u002Fjats:p>",{"EN":1347,"VI":1348},"Hematology and Plasma Chemistry Reference Intervals for Cultured Tilapia (\u003Ci>Oreochromis\u003C\u002Fi>Hybrid)","Tham Chiếu Huyết Học và Hóa Học Plasma cho Cá Nuôi Tilapia (\u003Ci>Oreochromis\u003C\u002Fi> lai)",{"VOID":1350},"12070816",{"VOID":1352},"10.1111\u002Fj.1939-165x.2000.tb00389.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.2000.tb00389.x",[1357,1376,1398],{"id":1358,"sortIndex":111,"researcher":24,"roles":1359,"affiliations":1360,"properties":1371},"67a896ec-e906-47a7-afe2-fe3e05252d65",[],[1361],{"id":1362,"sortIndex":25,"affiliation":1363,"properties":24},"0e5e1217-ea95-494d-ad43-b87a96acebca",{"id":1364,"createTime":1365,"updateTime":1365,"relativeEntities":1366,"slug":1367,"properties":1368,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"35118485-63c7-4d27-bc70-1f5773000778","2024-09-28T15:01:22.929+00:00",[],"Department-of-Biomedical-Sciences-and-Pathobiology-Virginia-Maryland-Regional-College-of-Veterinary-Medicine-Virginia-Polytechnic-Institute-and-State-University-Blacksburg-VA-24061-",{"title":1369},{"EN":1370},"Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061;",{"openalex":1372,"title":1374},{"VOID":1373},"A5037147049",{"EN":1375},"Jenifer L. Cardinale",{"id":1377,"sortIndex":25,"researcher":24,"roles":1378,"affiliations":1379,"properties":1391},"9333a1a3-d542-4b1c-9d21-93ad0f5cab86",[],[1380],{"id":1381,"sortIndex":25,"affiliation":1382,"properties":24},"e0583bea-4294-43bc-8a25-cbefcb10a856",{"id":1383,"createTime":1384,"updateTime":1385,"relativeEntities":1386,"slug":1387,"properties":1388,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"8425b0d7-c167-4248-b4a7-89be7294ed87","2024-01-17T20:28:26.663+00:00","2024-09-28T15:01:22.914+00:00",[],"Department-of-Biomedical-Sciences-and-Pathobiology-Virginia-Maryland-Regional-College-of-Veterinary-Medicine-Virginia-Polytechnic-Institute-and-State-University-Blacksburg-VA-24061-USA",{"title":1389},{"VI":1390},"Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA",{"openalex":1392,"orcid":1394,"title":1396},{"VOID":1393},"A5022610259",{"VOID":1395},"https:\u002F\u002Forcid.org\u002F0000-0002-3961-9201",{"EN":1397},"Terry C. Hrubec",{"id":1399,"sortIndex":108,"researcher":24,"roles":1400,"affiliations":1401,"properties":1408},"ea83e11a-7ea4-4a91-93f1-b0e5c9c37cd7",[],[1402],{"id":1403,"sortIndex":25,"affiliation":1404,"properties":24},"efeed65e-0347-489d-9025-9d7cf8ad2baa",{"id":1364,"createTime":1365,"updateTime":1365,"relativeEntities":1405,"slug":1367,"properties":1406,"entityType":52,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1407},{"EN":1370},{"openalex":1409,"orcid":1411,"title":1413},{"VOID":1410},"A5087290208",{"VOID":1412},"https:\u002F\u002Forcid.org\u002F0000-0003-4104-1899",{"EN":1414},"Stephen A. 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Proposed Guidelines",{},{"id":24,"text":1485,"url":24,"identifiers":1486},"Terao T, 1984, On the biochemical components in the blood of the cultured cichlid fish Tilapia nilotica, Sci Rep Hokkaido Fish Hatchery, 39, 83",{},{"id":24,"text":1488,"url":24,"identifiers":1489},"Haniffa MA, 1989, Hematological effects of textile mill effluent on freshwater fish Oreochromis mossambicus (Trewaves), Ind J Exp Biol, 27, 476",{},{"id":24,"text":1491,"url":24,"identifiers":1492},"10.1007\u002Fs001289900218",{"doi":1491},{"id":24,"text":1494,"url":24,"identifiers":1495},"10.1111\u002Fj.1095-8649.1989.tb03354.x",{"doi":1494},{"id":24,"text":1497,"url":24,"identifiers":1498},"Hrubec TC, 1996, Comparison of hematologic reference intervals between culture system and type of hybrid striped bass, AmJ Vet Res, 57, 618, 10.2460\u002Fajvr.1996.57.05.618",{"doi":1499},"10.2460\u002Fajvr.1996.57.05.618",{"id":24,"text":1501,"url":24,"identifiers":1502},"Hrubec TC, 1996, Blood biochemical reference intervals for sunshine bass (Morone chrysopsX Morone saxatilis) in three culture systems, Am J Vet Res, 57, 624, 10.2460\u002Fajvr.1996.57.05.624",{"doi":1503},"10.2460\u002Fajvr.1996.57.05.624",{"id":24,"text":1505,"url":24,"identifiers":1506},"10.1093\u002Fclinchem\u002F17.4.275",{"doi":1505},{"id":24,"text":1508,"url":24,"identifiers":1509},"10.1111\u002Fj.1939-165X.1998.tb01027.x",{"doi":1508},{"id":24,"text":1511,"url":24,"identifiers":1512},"Hrubec TC, 1997, Effects of temperature on hematologic and serum biochemical profiles of hybrid striped bass (Morone chrysops X Morone saxatilis), Am J Vet Res, 58, 126, 10.2460\u002Fajvr.1997.58.02.126",{"doi":1513},"10.2460\u002Fajvr.1997.58.02.126",{"id":24,"text":1515,"url":24,"identifiers":1516},"Hrubec TC, 1997, Effects of ammonia and nitrate concentration on hematologic and serum biochemical profiles of hybrid striped bass (Morone chrysops X Morone saxatilis), Am J Vet Res, 58, 131, 10.2460\u002Fajvr.1997.58.02.131",{"doi":1517},"10.2460\u002Fajvr.1997.58.02.131",{"id":1519,"createTime":1520,"updateTime":1521,"relativeEntities":1522,"slug":1523,"properties":1524,"entityType":150,"verifyStatus":23,"verifyTime":1520,"verifyNote":639,"syncStatus":23,"languages":1541,"translateLanguages":1542,"viewCount":25,"primaryUrl":1543,"fullTextUrl":24,"authors":1544,"publicationType":258,"publisherRelationship":1624,"citationCount":1661,"citationInfo":1662,"publishDate":1665,"publishYear":1666,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1667,"isForceReanalyzing":348},"52649d16-343d-40cc-8784-9bea8f760ca9","2024-11-26T11:21:39.682+00:00","2024-12-24T16:45:09.714+00:00",[],"Relationship-between-haptoglobin-serum-amyloid-A-and-clinical-status-in-a-survey-of-dairy-herds-during-a-6-month-period",{"mag":1525,"keywords":1527,"openalex":1529,"abstract":1531,"title":1534,"pm":1537,"doi":1539},{"VOID":1526},"2157716759",{"VI":1528},"haptoglobin, amyloid A huyết thanh, bò sữa, pha cấp, quanh sinh, sức khỏe lâm sàng, viêm, chuẩn đoán bệnh",{"VOID":1530},"W2157716759",{"EN":1532,"VI":1533},"\u003Cjats:p> \u003Cjats:bold>Background:\u003C\u002Fjats:bold> Haptoglobin and serum amyloid A are major acute phase proteins in cattle. Dairy cattle often develop pathologic conditions in the peripartum period; acute phase proteins may be useful in their diagnosis. \u003Cjats:bold>Objectives:\u003C\u002Fjats:bold> The purpose of this study was to compare the accuracy of serum haptoglobin (Hp) and serum amyloid A (SAA) concentrations with clinical health status for diagnosing disease during the peripartum period in dairy cattle. \u003Cjats:bold>Methods:\u003C\u002Fjats:bold> Dairy cows from 4 herds were evaluated every 15 days over a 6‐month period. Health status was determined by thorough clinical examination. Haptoglobin and SAA concentrations were measured in serum using validated methods and the results were classifed as positive or negative based on defined cutoff points. Disease prevalence, sensitivity, and specificity were compared using clinical examination as the gold standard. \u003Cjats:bold>Results:\u003C\u002Fjats:bold> A total of 1896 samples from 158 cows were analyzed. Significant increases in mean Hp and SAA concentrations were observed in the week following parturition in both primiparous and multiparous cows, although high interindividual variability was observed. Both Hp and SAA had low sensitivity but higher specificity in determining disease status compared with clinical examination. Increased concentrations of Hp and SAA were found in <10% of samples from clinically healthy cows, except in the week after parturition. \u003Cjats:bold>Conclusions:\u003C\u002Fjats:bold> Haptoglobin and serum amyloid A should be used with caution as markers of inflammation in the week after calving. Poor sensitivity in other postpartum periods could be related to the higher incidence of chronic (vs acute) inflammation. Haptoglobin may be appropriate for routine screening, but further work needs to be done to assess its value as an indicator of herd health. (\u003Cjats:italic>Vet Clin Pathol.\u003C\u002Fjats:italic> 2006;35:000–000)\u003C\u002Fjats:p>","\u003Cjats:p> \u003Cjats:bold>Tổng quan:\u003C\u002Fjats:bold> Haptoglobin và serum amyloid A là các protein pha cấp chính ở bò. Bò sữa thường phát triển các tình trạng bệnh lý trong giai đoạn quanh sinh; các protein pha cấp có thể hữu ích trong chẩn đoán bệnh của chúng. \u003Cjats:bold>Mục tiêu:\u003C\u002Fjats:bold> Mục đích của nghiên cứu này là so sánh độ chính xác của nồng độ haptoglobin huyết thanh (Hp) và amyloid A huyết thanh (SAA) với tình trạng sức khỏe lâm sàng để chẩn đoán bệnh trong giai đoạn quanh sinh ở bò sữa. \u003Cjats:bold>Phương pháp:\u003C\u002Fjats:bold> Bò sữa từ 4 đàn bò đã được đánh giá mỗi 15 ngày trong suốt 6 tháng. Tình trạng sức khỏe được xác định thông qua thăm khám lâm sàng kỹ lưỡng. Nồng độ Haptoglobin và SAA được đo trong huyết thanh bằng các phương pháp đã được kiểm chứng và kết quả được phân loại là dương tính hoặc âm tính dựa trên các ngưỡng cắt đã được xác định. Tỷ lệ mắc bệnh, độ nhạy và độ đặc hiệu đã được so sánh sử dụng thăm khám lâm sàng như tiêu chuẩn vàng. \u003Cjats:bold>Kết quả:\u003C\u002Fjats:bold> Tổng cộng 1896 mẫu từ 158 con bò được phân tích. Sự gia tăng đáng kể nồng độ trung bình Hp và SAA được quan sát thấy trong tuần sau sinh ở cả bò đẻ lứa đầu và bò đẻ nhiều lứa, mặc dù có sự biến đổi cá nhân cao. Cả Hp và SAA đều có độ nhạy thấp nhưng độ đặc hiệu cao hơn trong xác định bệnh so với thăm khám lâm sàng. Nồng độ Hp và SAA tăng cao được tìm thấy trong <10% mẫu từ các con bò khỏe mạnh về mặt lâm sàng, ngoại trừ trong tuần sau sinh. \u003Cjats:bold>Kết luận:\u003C\u002Fjats:bold> Haptoglobin và amyloid A huyết thanh nên được sử dụng cẩn thận như các dấu hiệu của viêm trong tuần sau đẻ. Độ nhạy kém trong các giai đoạn hậu sinh sản khác có thể liên quan đến tỷ lệ viêm mãn tính (so với cấp tính) cao hơn. Haptoglobin có thể phù hợp cho sàng lọc định kỳ, nhưng cần thêm nghiên cứu để đánh giá giá trị của nó như một chỉ số về sức khỏe đàn bò. (\u003Cjats:italic>Vet Clin Pathol.\u003C\u002Fjats:italic> 2006;35:000–000)\u003C\u002Fjats:p>",{"EN":1535,"VI":1536},"Relationship between haptoglobin, serum amyloid A, and clinical status in a survey of dairy herds during a 6‐month period","Mối quan hệ giữa haptoglobin, serum amyloid A và tình trạng lâm sàng trong cuộc khảo sát các đàn bò sữa trong thời gian 6 tháng",{"VOID":1538},"16783711",{"VOID":1540},"10.1111\u002Fj.1939-165x.2006.tb00112.x",[154],[156],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1939-165X.2006.tb00112.x",[1545,1554,1563,1572,1583,1594,1615],{"id":1546,"sortIndex":198,"researcher":24,"roles":1547,"affiliations":1548,"properties":1549},"f3cb8637-f094-438b-a5c2-d4ee69ec3b12",[],[],{"openalex":1550,"title":1552},{"VOID":1551},"A5046633817",{"EN":1553},"Faustin 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20",{},{"id":24,"text":1733,"url":24,"identifiers":1734},"HumbletM‐F.Validation de l'Haptoglobine sérique en tant que marqueur de l'inflammation aiguë dans l'espèce bovine [Validation of serum haptoglobin as an acute phase protein in cattle].PhD Thesis. 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Plasma haptoglobin level in cattle under pathological conditions, Arch Exp Veterinarmed, 30, 193",{},{"id":24,"text":1739,"url":24,"identifiers":1740},"Tietz NW, 1987, Fundamentals of Clinical Chemistry., 202",{},{"id":24,"text":1742,"url":24,"identifiers":1743},"10.1016\u002FS0093-691X(98)00029-6",{"doi":1742},{"id":24,"text":1745,"url":24,"identifiers":1746},"10.1292\u002Fjvms.55.893",{"doi":1745},{"id":24,"text":1748,"url":24,"identifiers":1749},"Skinner JG, 1992, Proceedings of the Vth Congress of the International Society for Animal Clinical Biochemistry,, 133",{},{"id":24,"text":1751,"url":24,"identifiers":1752},"Alsemgeest SPM, 1993, Peripartum acute‐phase protein serum amyloid A concentration in plasma of cows and fetuses, Am J Vet Res, 54, 165",{},{"id":24,"text":1754,"url":24,"identifiers":1755},"10.3168\u002Fjds.S0022-0302(04)73469-4",{"doi":1754},{"id":24,"text":1757,"url":24,"identifiers":1758},"10.1136\u002Fvr.144.16.437",{"doi":1757},{"id":24,"text":1760,"url":24,"identifiers":1761},"10.1136\u002Fvr.142.4.83",{"doi":1760},{"id":24,"text":1763,"url":24,"identifiers":1764},"10.1016\u002FS0093-691X(99)80012-0",{"doi":1763},{"id":24,"text":1766,"url":24,"identifiers":1767},"10.1006\u002Fabio.1996.0136",{"doi":1766},{"id":24,"text":1769,"url":24,"identifiers":1770},"10.1056\u002FNEJM199902113400607",{"doi":1769},{"id":1772,"createTime":1773,"updateTime":1773,"relativeEntities":1774,"slug":1775,"properties":1776,"entityType":150,"verifyStatus":151,"verifyTime":1773,"verifyNote":152,"syncStatus":23,"languages":1790,"translateLanguages":24,"viewCount":25,"primaryUrl":1791,"fullTextUrl":24,"authors":1792,"publicationType":258,"publisherRelationship":1848,"citationCount":1884,"citationInfo":1885,"publishDate":1887,"publishYear":756,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1888,"isForceReanalyzing":348},"63eef09c-e535-4212-94ec-4c48d227ed01","2025-02-08T12:22:44.580+00:00",[],"Evaluation-of-platelet-count-and-its-association-with-plateletcrit-mean-platelet-volume-and-platelet-size-distribution-width-in-a-canine-model-of-endotoxemia",{"mag":1777,"keywords":1779,"openalex":1780,"abstract":1782,"title":1784,"pm":1786,"doi":1788},{"VOID":1778},"2035650256",{},{"VOID":1781},"W2035650256",{"EN":1783},"\u003Cjats:p>\u003Cjats:bold>Background: \u003C\u002Fjats:bold> Platelets are of great importance in the pathogenesis of endotoxemia. Although thrombocytopenia is used as a diagnostic sign of endotoxemia, changes in values for platelet indices (plateletcrit [PCT], mean platelet volume [MPV], and platelet size distribution width [PDW]) in response to endotoxin are still unknown.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Objective: \u003C\u002Fjats:bold> The aim of this study was to evaluate platelet count and its relations with platelet indices in a canine model of endotoxemia.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Methods: \u003C\u002Fjats:bold> Twenty dogs were divided into 2 groups of 10 each, and treated intravenously with \u003Cjats:italic>Escherichia coli\u003C\u002Fjats:italic> endotoxin (1 mg\u002Fkg) or vehicle. Venous blood samples were collected before treatment (0 hour) and 0.5, 1, 2, 4, 6, 8, 12, and 24 hours after treatment. Platelet counts and indices were determined on a CELL‐DYN hematology analyzer.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Results: \u003C\u002Fjats:bold> The platelet count and PCT decreased by a mean of 73% and 93%, respectively (\u003Cjats:italic>P\u003C\u002Fjats:italic><.001), at 0.5 hour, and remained 70% and 85% lower than baseline values (\u003Cjats:italic>P\u003C\u002Fjats:italic><.001) for 24 hours after endotoxin injection. MPV and PDW increased by a mean of 28% and 45%, respectively (\u003Cjats:italic>P\u003C\u002Fjats:italic><.01), at 0.5 hour, and remained increased by 7% and 16% over baseline values for 24 hours (\u003Cjats:italic>P\u003C\u002Fjats:italic><.01–.001). Platelet count correlated positively with PCT (\u003Cjats:italic>P\u003C\u002Fjats:italic><.001), but correlated negatively with MPV (\u003Cjats:italic>P\u003C\u002Fjats:italic><.001) and PDW (\u003Cjats:italic>P\u003C\u002Fjats:italic><.01).\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Conclusions: \u003C\u002Fjats:bold> Changes in platelet count and its association with platelet indices may reflect changes in platelet production and reactivity. Platelet indices have potential value in the diagnosis and monitoring of dogs and humans with endotoxemia.\u003C\u002Fjats:p>",{"EN":1785},"Evaluation of platelet count and its association with plateletcrit, mean platelet volume, and platelet size distribution width in a canine model of 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