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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":487,"VI":488},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":490},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[494],{"id":495,"createTime":28,"updateTime":28,"relativeEntities":496,"slug":28,"properties":497,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":507,"parentIds":508,"statistic":28},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":498,"address":501,"country":504,"abbreviation":505},{"EN":499,"VI":500},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":502,"VI":503},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":15},{"VOID":506},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":32,"impactFactorByYear":512,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":514,"totalPublicationByYear":515,"totalCitation":520,"totalCitationByYear":521,"totalCitationPerPublication":108,"totalCitationPerPublicationByYear":523,"hindexLast5Year":45,"hindex":45},{"2022":513,"2023":111,"2024":106},0.01,1556,{"2020":47,"2021":516,"2022":517,"2023":518,"2024":519,"2025":122},57,306,801,358,161,{"2021":146,"2022":280,"2023":522},99,{"2021":524,"2022":318,"2023":104},0.23,{"impactFactor":28,"impactFactorByYear":28,"i10Index":123,"i10IndexLast5Year":123,"totalPublication":526,"totalPublicationByYear":527,"totalCitation":526,"totalCitationByYear":528,"totalCitationPerPublication":40,"totalCitationPerPublicationByYear":531,"hindexLast5Year":49,"hindex":49},476,{"0":205,"2019":123,"2021":139,"2022":459,"2023":451,"2024":357,"2025":49,"2026":48},{"2021":42,"2022":123,"2023":161,"2024":529,"2025":360,"2026":530},136,83,{"2021":105,"2022":513,"2023":532,"2024":127,"2025":533,"2026":534},0.62,25.43,13.83,{"id":536,"createTime":537,"updateTime":382,"relativeEntities":538,"slug":539,"properties":540,"entityType":25,"verifyStatus":26,"verifyTime":28,"verifyNote":28,"languages":552,"translateLanguages":28,"viewCount":133,"subjectFields":553,"manageAffiliations":554,"indexDatabases":555,"url":556,"thumbnailPath":557,"statistic":558,"gsStatistic":594,"type":55,"analyzePriority":28},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":541,"issn":542,"title":544,"introduce":547,"gsId":550},{"VOID":15},{"VOID":543},"25252445",{"EN":545,"VI":546},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":548,"VI":549},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. 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The point of view of the journal is that infection and allograft rejection (or graft-versus-host disease) are closely intertwined, and that advances in one area will have immediate consequences on the other. The interaction of the transplant recipient with potential microbial invaders, the impact of immunosuppressive strategies on this interaction, and the effects of cytokines, growth factors, and chemokines liberated during the course of infections, rejection, or graft-versus-host disease are central to the interests and mission of this journal. Transplant Infectious Disease is aimed at disseminating the latest information relevant to the infectious disease complications of transplantation to clinicians and scientists involved in bone marrow, kidney, liver, heart, lung, intestinal, and pancreatic transplantation. The infectious disease consequences and concerns regarding innovative transplant strategies, from novel immunosuppressive agents to xenotransplantation, are very much a concern of this journal. In addition, this journal feels a particular responsibility to inform primary care practitioners in the community, who increasingly are sharing the responsibility for the care of these patients, of the special considerations regarding the prevention and treatment of infection in transplant recipients. 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Từ ngày 1\u002F1\u002F99 đến 31\u002F12\u002F02, 600 bệnh nhân nhận ghép thận và 102 bệnh nhân nhận ghép tụy-khách đã được ghép. Ba mươi chín (5,5%) trong số những bệnh nhân này đã bị CDC dựa trên các phát hiện lâm sàng và xét nghiệm. Trong số 39 bệnh nhân này, có 35 bệnh nhân thông tin sẵn có để xem xét. CDC phát triển vào khoảng thời gian trung bình 30 ngày sau khi ghép, và các bệnh nhân trải qua ghép tụy-khách có tỷ lệ mắc CDC cao hơn một chút so với những người nhận ghép thận đơn thuần (7,8% so với 4,5%, \u003Cjats:italic>P\u003C\u002Fjats:italic>&gt;0,05). Tất cả ngoại trừ một bệnh nhân đều có triệu chứng tiêu chảy. Hai mươi bốn bệnh nhân (64,9%) được chẩn đoán trong bệnh viện, và CDC xảy ra trong lần nhập viện đầu tiên ở 14 bệnh nhân (40%). Phác đồ điều trị sử dụng metronidazole đường uống (M) cho 33 bệnh nhân (94%) và M+vancomycin đường uống (M+V) cho 2 bệnh nhân. Tám bệnh nhân có CDC tái phát, xảy ra vào khoảng thời gian trung bình 30 ngày (phạm vi 15–314) sau lần đầu tiên. Hai bệnh nhân (5,7%) phát triển CDC cấp tính, biểu hiện với megacolon độc, và đã trải qua phẫu thuật cắt đại tràng. Một trong số họ đã tử vong; bệnh nhân còn lại sống sót sau khi cắt đại tràng. CDC nên được xem xét như một chẩn đoán ở bệnh nhân ghép tạng có tiền sử tiêu chảy sau khi sử dụng kháng sinh, và nên được điều trị kịp thời trước khi nhiễm trùng trở nên phức tạp.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> Limited data exist about \u003Cjats:italic>Clostridium difficile\u003C\u002Fjats:italic> colitis (CDC) in solid organ transplant patients. Between 1\u002F1\u002F99 and 12\u002F31\u002F02, 600 kidney and 102 pancreas–kidney allograft recipients were transplanted. Thirty‐nine (5.5%) of these patients had CDC on the basis of clinical and laboratory findings. Of these 39 patients, 35 have information available for review. CDC developed at a median of 30 days after transplantation, and the patients undergoing pancreas–kidney transplantation had a slightly higher incidence of CDC than recipients of kidney alone (7.8% vs. 4.5%, \u003Cjats:italic>P\u003C\u002Fjats:italic>&gt;0.05). All but one patient presented with diarrhea. Twenty‐four patients (64.9%) were diagnosed in the hospital, and CDC occurred during first hospitalization in 14 patients (40%). Treatment was with oral metronidazole (M) in 33 patients (94%) and M+oral vancomycin (M+V) in 2 patients. Eight patients had recurrent CDC, which occurred at a median of 30 days (range 15–314) after the first episode. Two patients (5.7%) developed fulminant CDC, presented with toxic megacolon, and underwent colectomy. One of them died; the other patient survived after colectomy. 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41",{},{"id":28,"text":1226,"url":28,"identifiers":1227},"10.1016\u002FS0022-3476(05)83393-1",{"doi":1226},false,{"id":1230,"createTime":1231,"updateTime":1232,"relativeEntities":1233,"slug":1234,"properties":1235,"entityType":975,"verifyStatus":26,"verifyTime":1252,"verifyNote":976,"languages":1253,"translateLanguages":1254,"viewCount":32,"primaryUrl":1255,"fullTextUrl":28,"authors":1256,"publicationType":1132,"publisherRelationship":1337,"citationCount":209,"citationInfo":1387,"publishDate":1390,"publishYear":1388,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":1391,"openAccess":28,"references":1392,"isForceReanalyzing":1228},"bfb81df2-3016-4f29-a446-140699ec7eb1","2024-10-07T07:35:35.355+00:00","2025-01-12T06:36:30.276+00:00",[],"The-role-of-antiviral-and-immunoglobulin-therapy-in-the-prevention-of-Epstein-Barr-virus-infection-and-post-transplant-lymphoproliferative-disease-following-solid-organ-transplantation",{"mag":1236,"keywords":1238,"openalex":1240,"abstract":1242,"title":1245,"pm":1248,"doi":1250},{"VOID":1237},"1967573121",{"VI":1239},"nhiễm virus Epstein–Barr, bệnh lý lympho bạch huyết hậu ghép, liệu pháp kháng virus, liệu pháp miễn dịch, phòng ngừa bệnh",{"VOID":1241},"W1967573121",{"VI":1243,"EN":1244},"\u003Cjats:p>\u003Cjats:bold>Tóm tắt:\u003C\u002Fjats:bold> Sự nhận thức về tầm quan trọng của nhiễm virus Epstein–Barr (EBV), bao gồm cả bệnh lympho bạch huyết hậu ghép tạng liên quan đến EBV (PTLD), đã dẫn đến một trọng tâm mới về việc phòng ngừa vấn đề này. Bài báo này xem xét cơ sở khoa học phía sau, cũng như kinh nghiệm lâm sàng với việc sử dụng liệu pháp hóa dự phòng (sử dụng acyclovir hoặc ganciclovir) và liệu pháp miễn dịch dự phòng (sử dụng immunoglobulin tĩnh mạch) trong việc phòng ngừa EBV\u002FPTLD. Trong khi một số trung tâm đã giới thiệu việc sử dụng một hoặc cả hai tác nhân này như là liệu pháp dự phòng chuẩn chống lại sự phát triển của biến chứng này, dữ liệu đã công bố ủng hộ các quy trình này hiện tại vẫn còn thiếu. Cần phải có các thử nghiệm lâm sàng được thiết kế tốt để đánh giá vai trò tiềm năng của cả hai tác nhân kháng virus và immunoglobulin trong việc phòng ngừa EBV\u002FPTLD ở những bệnh nhân ghép tạng.","\u003Cjats:p>\u003Cjats:bold>Abstract:\u003C\u002Fjats:bold> The recognition of the importance of Epstein–Barr virus (EBV) infection, including EBV‐associated post‐transplant lymphoproliferative disease (PTLD), has led to a new focus on the prevention of this problem. This paper reviews the scientific rationale behind, and clinical experience with, the use of chemoprophylaxis (using acyclovir or ganciclovir) and immunoprophylaxis (using intravenous immunoglobulin) in the prevention of EBV\u002FPTLD. While some centers have already introduced the use of one or both of these agents as standard prophylaxis against the development of this complication, published data in support of these protocols are currently lacking. Well designed clinical trials are necessary to evaluate the potential role of both antiviral and immunoglobulin agents in the prevention of EBV\u002FPTLD in organ transplant recipients.\u003C\u002Fjats:p>",{"EN":1246,"VI":1247},"The role of antiviral and immunoglobulin therapy in the prevention of Epstein–Barr virus infection and post‐transplant lymphoproliferative disease following solid organ transplantation","Vai trò của liệu pháp kháng virus và miễn dịch trong việc phòng ngừa nhiễm virus Epstein–Barr và bệnh lý lympho bạch huyết sau ghép tạng",{"VOID":1249},"11395975",{"VOID":1251},"10.1034\u002Fj.1399-3062.2001.003002097.x","2024-10-07T07:35:35.354+00:00",[31],[30],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1034\u002Fj.1399-3062.2001.003002097.x",[1257,1284,1301,1318],{"id":1258,"sortIndex":32,"researcher":28,"roles":1259,"affiliations":1260,"properties":1277,"displayName":1281,"givenName":28,"familyName":28},"1b2606b3-546e-435c-885c-785378c8fe1b",[],[1261,1269],{"id":1262,"sortIndex":32,"affiliation":1263,"properties":28},"09d9ad76-7f7d-4b05-8242-52a5c480f63f",{"id":1262,"createTime":28,"updateTime":28,"relativeEntities":1264,"slug":28,"properties":1265,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1268,"statistic":28},[],{"title":1266},{"VI":1267},"‡Department of Pediatrics and",[],{"id":1270,"sortIndex":40,"affiliation":1271,"properties":28},"7777d108-1692-4742-b1a8-4449313734bb",{"id":1270,"createTime":28,"updateTime":28,"relativeEntities":1272,"slug":28,"properties":1273,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1276,"statistic":28},[],{"title":1274},{"EN":1275},"Department of Surgery, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA",[],{"orcid":1278,"title":1280,"openalex":1282},{"VOID":1279},"https:\u002F\u002Forcid.org\u002F0000-0002-6011-2894",{"EN":1281},"Michael Green",{"VOID":1283},"A5100628988",{"id":1285,"sortIndex":40,"researcher":28,"roles":1286,"affiliations":1287,"properties":1294,"displayName":1298,"givenName":28,"familyName":28},"f7aa7388-50d1-4fae-b40d-2be690b7bf98",[],[1288],{"id":1270,"sortIndex":32,"affiliation":1289,"properties":28},{"id":1270,"createTime":28,"updateTime":28,"relativeEntities":1290,"slug":28,"properties":1291,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1293,"statistic":28},[],{"title":1292},{"EN":1275},[],{"orcid":1295,"title":1297,"openalex":1299},{"VOID":1296},"https:\u002F\u002Forcid.org\u002F0000-0003-3065-8674",{"EN":1298},"Jorgé Reyes",{"VOID":1300},"A5057154255",{"id":1302,"sortIndex":123,"researcher":28,"roles":1303,"affiliations":1304,"properties":1311,"displayName":1315,"givenName":28,"familyName":28},"40b889bd-aeba-43db-89d8-3cf093d75bbb",[],[1305],{"id":1262,"sortIndex":32,"affiliation":1306,"properties":28},{"id":1262,"createTime":28,"updateTime":28,"relativeEntities":1307,"slug":28,"properties":1308,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1310,"statistic":28},[],{"title":1309},{"VI":1267},[],{"orcid":1312,"title":1314,"openalex":1316},{"VOID":1313},"https:\u002F\u002Forcid.org\u002F0000-0003-4865-5666",{"EN":1315},"Steven A. Webber",{"VOID":1317},"A5054641853",{"id":1319,"sortIndex":42,"researcher":28,"roles":1320,"affiliations":1321,"properties":1330,"displayName":1334,"givenName":28,"familyName":28},"e0fe37c0-c424-4961-a6ee-c45d5fbfe99f",[],[1322],{"id":1323,"sortIndex":32,"affiliation":1324,"properties":28},"2ecfee14-cd41-401c-9065-327441a877a8",{"id":1323,"createTime":28,"updateTime":28,"relativeEntities":1325,"slug":28,"properties":1326,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1329,"statistic":28},[],{"title":1327},{"VI":1328},"Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania USA",[],{"orcid":1331,"title":1333,"openalex":1335},{"VOID":1332},"https:\u002F\u002Forcid.org\u002F0000-0001-7281-903X",{"EN":1334},"David Rowe",{"VOID":1336},"A5064635209",{"url":28,"publisher":1338,"properties":1380},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1339,"slug":872,"properties":1340,"entityType":25,"verifyStatus":884,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1345,"manageAffiliations":1354,"indexDatabases":1365,"url":945,"thumbnailPath":28,"statistic":28,"gsStatistic":28,"type":28,"analyzePriority":28},[],{"country":1341,"eissn":1342,"issn":1343,"title":1344},{"VOID":875},{"VOID":877},{"VOID":879},{"EN":881},[1346,1350],{"id":887,"createTime":28,"updateTime":28,"relativeEntities":1347,"label":1348,"description":1349,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":890},{},{"id":893,"createTime":28,"updateTime":28,"relativeEntities":1351,"label":1352,"description":1353,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":896},{},[1355,1360],{"id":900,"createTime":28,"updateTime":28,"relativeEntities":1356,"slug":28,"properties":1357,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1359,"statistic":28},[],{"title":1358},{"EN":904},[],{"id":907,"createTime":28,"updateTime":28,"relativeEntities":1361,"slug":28,"properties":1362,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1364,"statistic":28},[],{"title":1363},{"EN":911},[],[1366,1373],{"id":915,"indexDatabase":1367,"url":927,"indexYears":28,"academicFieldIds":1372,"indexDatabaseRanking":28},{"id":917,"createTime":28,"updateTime":28,"relativeEntities":1368,"label":1369,"description":1370,"key":924,"publicationTags":1371,"standard":28},[],{"EN":920,"VI":920},{"EN":922,"VI":923},[926,813],[929,930,931],{"id":933,"indexDatabase":1374,"url":939,"indexYears":940,"academicFieldIds":1379,"indexDatabaseRanking":944},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":1375,"label":1376,"description":1377,"key":781,"publicationTags":1378,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],[942,943],{"issue":1381,"pages":1383,"volume":1385},{"VOID":1382},"2",{"VOID":1384},"97-103",{"VOID":1386},"3",{"total":209,"publishYear":1388,"statisticByYear":1389},2001,{"2012":123,"2013":123,"2014":123,"2015":42,"2016":42,"2017":42,"2018":123,"2020":40,"2021":42,"2022":40},"2001-06-01",[944,926],[1393,1396,1399,1402,1406,1410,1413,1416,1419,1423,1426,1429,1433,1437,1440,1443,1446,1449,1452,1455,1458,1461,1464,1467,1470,1473,1476,1479,1482,1485],{"id":28,"text":1394,"url":28,"identifiers":1395},"10.1097\u002F00007890-199911270-00015",{"doi":1394},{"id":28,"text":1397,"url":28,"identifiers":1398},"10.1034\u002Fj.1399-3046.1999.00066.x",{"doi":1397},{"id":28,"text":1400,"url":28,"identifiers":1401},"10.1007\u002Fs002810050046",{"doi":1400},{"id":28,"text":1403,"url":28,"identifiers":1404},"Lin JC, 1984, Prolonged inhibitory effect of 9‐(1,3‐dihydroxy‐2‐propoxymethyl)guanine against replication of Epstein–Barr virus., J Virol, 50, 50, 10.1128\u002Fjvi.50.1.50-55.1984",{"doi":1405},"10.1128\u002Fjvi.50.1.50-55.1984",{"id":28,"text":1407,"url":28,"identifiers":1408},"Knowles DM, 1995, Correlative morphologic and molecular genetic analysis demonstrates three distinct categories of posttransplantation lymphoproliferative disorders., Blood, 85, 552, 10.1182\u002Fblood.V85.2.552.552",{"doi":1409},"10.1182\u002Fblood.V85.2.552.552",{"id":28,"text":1411,"url":28,"identifiers":1412},"10.1007\u002Fs002810050042",{"doi":1411},{"id":28,"text":1414,"url":28,"identifiers":1415},"10.1056\u002FNEJM198204153061506",{"doi":1414},{"id":28,"text":1417,"url":28,"identifiers":1418},"10.1097\u002F00007890-199608150-00012",{"doi":1417},{"id":28,"text":1420,"url":28,"identifiers":1421},"Riddler SA, 1994, Increased levels of circulating Epstein–Barr virus‐infected lymphocytes and decreased EBV nuclear antigen antibody responses are associated with the development of posttransplant lymphoproliferative disease in solid‐organ transplant recipients., Blood, 84, 972, 10.1182\u002Fblood.V84.3.972.972",{"doi":1422},"10.1182\u002Fblood.V84.3.972.972",{"id":28,"text":1424,"url":28,"identifiers":1425},"10.1097\u002F00007890-199509270-00005",{"doi":1424},{"id":28,"text":1427,"url":28,"identifiers":1428},"10.1111\u002Fj.1365-2141.1995.tb08904.x",{"doi":1427},{"id":28,"text":1430,"url":28,"identifiers":1431},"Rowe DT, 1997, Use of quantitative competitive PCR to measure Epstein–Barr virus genome load in peripheral blood of pediatric transplant recipients with lymphoproliferative disorders., J Clin Microbiol, 35, 1612, 10.1128\u002Fjcm.35.6.1612-1615.1997",{"doi":1432},"10.1128\u002Fjcm.35.6.1612-1615.1997",{"id":28,"text":1434,"url":28,"identifiers":1435},"Savoie A, 1994, Direct correlation between the load of Epstein–Barr virus‐infected lymphocytes in the peripheral blood of pediatric transplant patients and risk of lymphoproliferative disease., Blood, 83, 2715, 10.1182\u002Fblood.V83.9.2715.2715",{"doi":1436},"10.1182\u002Fblood.V83.9.2715.2715",{"id":28,"text":1438,"url":28,"identifiers":1439},"10.1084\u002Fjem.190.4.567",{"doi":1438},{"id":28,"text":1441,"url":28,"identifiers":1442},"10.1086\u002F315828",{"doi":1441},{"id":28,"text":1444,"url":28,"identifiers":1445},"Boyle TJ, 1992, Human B‐cell lymphoma in severe combined immunodeficient mice after active infection with Epstein–Barr virus., Surgery, 112, 378",{},{"id":28,"text":1447,"url":28,"identifiers":1448},"10.1097\u002F00007890-199812270-00006",{"doi":1447},{"id":28,"text":1450,"url":28,"identifiers":1451},"10.1097\u002F00007890-199709270-00010",{"doi":1450},{"id":28,"text":1453,"url":28,"identifiers":1454},"Davis CL, 1995, Antiviral prophylaxis and the Epstein–Barr virus‐related post‐transplant lymphoproliferative disorder., Clin Transplant, 9, 53",{},{"id":28,"text":1456,"url":28,"identifiers":1457},"10.1056\u002FNEJM199104113241509",{"doi":1456},{"id":28,"text":1459,"url":28,"identifiers":1460},"10.1086\u002F514142",{"doi":1459},{"id":28,"text":1462,"url":28,"identifiers":1463},"10.1093\u002Fclinids\u002F20.5.1346",{"doi":1462},{"id":28,"text":1465,"url":28,"identifiers":1466},"10.1086\u002F516139",{"doi":1465},{"id":28,"text":1468,"url":28,"identifiers":1469},"10.1097\u002F00007890-199501150-00024",{"doi":1468},{"id":28,"text":1471,"url":28,"identifiers":1472},"10.3109\u002F10428199409051672",{"doi":1471},{"id":28,"text":1474,"url":28,"identifiers":1475},"10.1002\u002F(sici)1097-0215(19970516)71:4\u003C624::aid-ijc19>3.0.co;2-b",{"doi":1474},{"id":28,"text":1477,"url":28,"identifiers":1478},"Nadal D, 1997, Human immunoglobulin preparations suppress the occurrence of Epstein–Barr virus‐associated lymphoproliferation., Exp Hematol, 25, 223",{},{"id":28,"text":1480,"url":28,"identifiers":1481},"10.1097\u002F00075200-199909000-00018",{"doi":1480},{"id":28,"text":1483,"url":28,"identifiers":1484},"10.1097\u002F00007890-200008270-00010",{"doi":1483},{"id":28,"text":1486,"url":28,"identifiers":1487},"10.1016\u002FS0140-6736(95)91150-2",{"doi":1486},{"id":1489,"createTime":1490,"updateTime":1491,"relativeEntities":1492,"slug":1493,"properties":1494,"entityType":975,"verifyStatus":26,"verifyTime":1490,"verifyNote":976,"languages":1510,"translateLanguages":1511,"viewCount":32,"primaryUrl":1512,"fullTextUrl":28,"authors":1513,"publicationType":1132,"publisherRelationship":1639,"citationCount":353,"citationInfo":1688,"publishDate":1691,"publishYear":1689,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":1692,"openAccess":28,"references":1693,"isForceReanalyzing":1228},"6d48ed77-df77-447c-826c-b57cb5bea075","2024-09-28T16:29:07.135+00:00","2025-01-12T06:37:27.894+00:00",[],"A-prospective-cross-sectional-study-of-BK-virus-infection-in-non-renal-solid-organ-transplant-recipients-with-chronic-renal-dysfunction",{"mag":1495,"keywords":1497,"openalex":1498,"abstract":1500,"title":1503,"pm":1506,"doi":1508},{"VOID":1496},"2128142915",{"VI":960},{"VOID":1499},"W2128142915",{"VI":1501,"EN":1502},"\u003Cjats:p>\u003Cjats:bold>Tóm tắt: Bối cảnh: \u003C\u002Fjats:bold> Nhiễm polyomavirus (chủ yếu là virus BK [BKV]) là nguyên nhân quan trọng gây ra rối loạn chức năng thận mãn tính ở người nhận ghép thận, nhưng ảnh hưởng của nó đến rối loạn chức năng thận mãn tính ở người nhận ghép tạng rắn không phải thận (NRSOT) vẫn chưa được khám phá đầy đủ.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Phương pháp: \u003C\u002Fjats:bold> Chúng tôi đã thực hiện một nghiên cứu cắt ngang tiềm năng đối với những người nhận ghép NRSOT liên tiếp có rối loạn chức năng thận mãn tính không rõ nguyên nhân kéo dài ít nhất 3 tháng. Hồ sơ y tế đã được xem xét và phương pháp phản ứng chuỗi polymerase đã được sử dụng để khuếch đại các trình tự đặc hiệu của BKV từ mẫu huyết thanh và nước tiểu. Các mối liên hệ tiềm năng giữa các biến số nhân khẩu học và ghép tạng khác nhau với nhiễm BKV đã được đánh giá.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Kết quả: \u003C\u002Fjats:bold> Ba mươi bốn người nhận ghép NRSOT liên tiếp (23 phổi, 8 gan, 2 tim, 1 tim-phổi) có rối loạn chức năng thận mãn tính đã được tuyển chọn với thời gian trung bình là 3,5 năm (dao động từ 0,3-12,5 năm) sau khi ghép. Năm trong số 34 bệnh nhân (15%) có BKV viruria (dao động từ 1040-1.8 × 10\u003Cjats:sup>6\u003C\u002Fjats:sup> copies\u002FmL), nhưng không có ai có BKV viremia. BK viruria có liên quan đến việc sử dụng mycophenolate mofetil (5 trong số 19 [26%] so với 0 trong số 15, \u003Cjats:italic>P\u003C\u002Fjats:italic>=0.03) và có tiền sử bệnh cytomegalovirus (3 trong số 4 [75%] so với 2 trong số 30 [7%], \u003Cjats:italic>P\u003C\u002Fjats:italic>&lt;0.01). Tuy nhiên, độ thanh thải creatinine ước lượng trung bình tương tự ở những bệnh nhân có hoặc không có BKV viruria (49 so với 47 mL\u002Fphút).\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Kết luận: \u003C\u002Fjats:bold> BKV viruria có mặt trong một tỷ lệ bệnh nhân NRSOT có rối loạn chức năng thận mãn tính không rõ nguyên nhân khác. Khả năng nhiễm BKV có thể góp phần vào rối loạn chức năng thận mãn tính trong bối cảnh này cần được nghiên cứu thêm.","\u003Cjats:p>\u003Cjats:bold>Abstract: Background: \u003C\u002Fjats:bold> Polyomavirus (primarily BK virus [BKV]) infection is an important cause of chronic renal dysfunction in renal transplant recipients, but its possible contribution to chronic renal dysfunction in non‐renal solid organ transplant (NRSOT) recipients has not been fully explored.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Methods: \u003C\u002Fjats:bold> We performed a prospective, cross‐sectional study of consecutive NRSOT recipients with unexplained chronic renal dysfunction of at least a 3 months duration. Medical records were reviewed, and polymerase chain reaction was used to amplify BKV‐specific sequences from serum and urine samples. The potential associations between various demographic and transplant variables and BKV infection were assessed.\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Results: \u003C\u002Fjats:bold> Thirty‐four consecutive NRSOT recipients (23 lung, 8 liver, 2 heart, 1 heart–lung) with chronic renal dysfunction were enrolled at a median of 3.5 years (range 0.3–12.5 years) post transplantation. Five of the 34 (15%) patients had BKV viruria (range 1040–1.8 × 10\u003Cjats:sup>6\u003C\u002Fjats:sup> copies\u002FmL), but none had BKV viremia. BK viruria was associated with mycophenolate mofetil use (5 of 19 [26%] vs. 0 of 15, \u003Cjats:italic>P\u003C\u002Fjats:italic>=0.03) and a history of cytomegalovirus disease (3 of 4 [75%] vs. 2 of 30 [7%], \u003Cjats:italic>P\u003C\u002Fjats:italic>&lt;0.01). However, the mean estimated creatinine clearance was similar in patients with or without BKV viruria (49 vs. 47 mL\u002Fmin).\u003C\u002Fjats:p>\u003Cjats:p>\u003Cjats:bold>Conclusions: \u003C\u002Fjats:bold> BKV viruria was present in a proportion of NRSOT patients with otherwise unexplained chronic renal dysfunction. The possibility that BKV infection might contribute to chronic renal dysfunction in this setting warrants further investigation.\u003C\u002Fjats:p>",{"EN":1504,"VI":1505},"A prospective cross‐sectional study of BK virus infection in non‐renal solid organ transplant recipients with chronic renal dysfunction","Nghiên cứu cắt ngang tiềm năng về nhiễm virus BK ở những người nhận ghép tạng rắn không phải thận mắc suy thận mãn tính",{"VOID":1507},"16734633",{"VOID":1509},"10.1111\u002Fj.1399-3062.2006.00155.x",[31],[30],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1399-3062.2006.00155.x",[1514,1531,1548,1567,1586,1603,1620],{"id":1515,"sortIndex":32,"researcher":28,"roles":1516,"affiliations":1517,"properties":1526,"displayName":1528,"givenName":28,"familyName":28},"9c4ba17c-84c1-49e2-a5c7-d0198aea51c8",[],[1518],{"id":1519,"sortIndex":32,"affiliation":1520,"properties":28},"ae874e6c-dfd9-42eb-825c-00c183c5f4a2",{"id":1519,"createTime":28,"updateTime":28,"relativeEntities":1521,"slug":28,"properties":1522,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1525,"statistic":28},[],{"title":1523},{"EN":1524},"Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, Philadelphia, Pennsylvania, USA",[],{"title":1527,"openalex":1529},{"EN":1528},"Todd D. 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E, 2001, BK virus in solid organ transplant recipients, an emerging syndrome, 72, 1587",{},{"id":28,"text":1752,"url":28,"identifiers":1753},"10.1111\u002Fj.1600-6143.2005.00742.x",{"doi":1752},{"id":28,"text":1755,"url":28,"identifiers":1756},"Puliyanda D, 2003, Heart and liver transplant recipients are at a low risk for polyoma virus BK viremia and nephropathy [abstract], Am J Transplant, 3, 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Chúng tôi đã xác định được 14 trường hợp bệnh Legionnaires xảy ra ở 2946 bệnh nhân ghép tạng rắn trong khoảng thời gian từ 1985 đến 2007. Hầu hết các trường hợp là rải rác và có nguồn gốc từ cộng đồng. Việc giới thiệu gần đây xét nghiệm kháng nguyên trong nước tiểu đã thúc đẩy quá trình chẩn đoán và cho phép thiết lập kịp thời liệu pháp phù hợp. Tỷ lệ tử vong tổng thể trong loạt nghiên cứu của chúng tôi là 14,3%. \u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> We identified 14 cases of Legionnaires' disease occurring in 2946 solid organ transplant recipients from 1985 to 2007. Most cases were sporadic and community acquired. The recent introduction of the urinary antigen test has accelerated diagnosis and allows prompt institution of adequate therapy. 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bào gốc đồng loại, miễn dịch tế bào, bệnh ghép chống chủ, nhiễm trùng lao",{"VOID":2055},"W1984093768",{"VI":2057,"EN":2058},"\u003Cjats:p>\u003Cjats:bold>Tóm tắt: \u003C\u002Fjats:bold> Bệnh nhân ghép tế bào gốc đồng loại (ASCT) có hệ thống miễn dịch tế bào bị suy giảm nghiêm trọng do phác đồ điều trị chuẩn bị, liệu pháp ức chế miễn dịch và bệnh ghép chống chủ (GVHD). Do đó, họ dễ bị nhiễm trùng do vi khuẩn, virus và nấm. Nhiễm trùng do vi khuẩn lao cũng có thể xảy ra ở những bệnh nhân này, mặc dù tỷ lệ không cao, ngay cả ở những quốc gia có tỷ lệ lao (TB) phổ biến. Chúng tôi mô tả bốn bệnh nhân từ bệnh viện của chúng tôi đã phát triển nhiễm trùng lao phổi trong giai đoạn hậu ghép trong khoảng thời gian 3 năm. Trong thời gian đó, tổng cộng 127 bệnh nhân đã trải qua ASCT, tỷ lệ mắc lao là 2.3%. Chẩn đoán trước ghép là bệnh bạch cầu cấp dòng tủy ở ba bệnh nhân và bệnh bạch cầu mãn dòng tủy ở một trường hợp. Cả bốn bệnh nhân đều được điều trị bằng sự kết hợp của cyclosporine và corticosteroids cho GVHD cấp tính và\u002Fhoặc mãn tính. Ba trong số bốn bệnh nhân sinh ra ngoài Australia, mỗi người từ một khu vực có tỷ lệ lao lưu hành. Hai bệnh nhân đã qua đời trong vòng 2 tuần kể từ khi bắt đầu liệu pháp chống lao, bệnh nhân thứ ba còn sống và khỏe mạnh, và bệnh nhân thứ tư qua đời do suy đa tạng và nhiễm trùng huyết sau 4 tháng trong bệnh viện. Cần phải có chỉ số nghi ngờ cao hơn về sự phơi nhiễm và nhiễm lao trước đó trong đánh giá bệnh nhân ASCT, đặc biệt là những người sinh ra từ những khu vực có tỷ lệ lao phổ biến hoặc lưu hành.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> Allogeneic stem cell transplant (ASCT) recipients have severely impaired cell‐mediated immunity as a result of their conditioning regimen, immunosuppressive therapy, and graft‐versus‐host disease (GVHD). Accordingly, they are susceptible to bacterial, viral, and fungal infections. Mycobacterial infections can also occur in these patients, although the incidence is not high, even in countries where tuberculosis (TB) is common. We describe four patients from our hospital who developed pulmonary T tuberculous infection in the post‐transplant period over a 3‐year period. During that time a total of 127 patients have undergone an ASCT, representing an incidence of TB of 2.3%. The pretransplant diagnosis was acute myeloid leukemia in three patients and chronic myeloid leukemia in one case. All four patients were treated with a combination of cyclosporine and corticosteroids for acute and\u002For chronic GVHD. Three of the four patients were born outside Australia, each from an area where TB is endemic. Two patients died within 2 weeks of the commencement of antituberculous therapy, the third is alive and well, and the fourth died of multi‐organ failure and sepsis after 4 months in hospital. 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Centers for Disease Control and Prevention, 46, 1",{},{"id":2256,"createTime":2257,"updateTime":2258,"relativeEntities":2259,"slug":2260,"properties":2261,"entityType":975,"verifyStatus":26,"verifyTime":2257,"verifyNote":976,"languages":2276,"translateLanguages":2277,"viewCount":32,"primaryUrl":2278,"fullTextUrl":28,"authors":2279,"publicationType":1132,"publisherRelationship":2445,"citationCount":130,"citationInfo":2492,"publishDate":2495,"publishYear":2493,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":2496,"openAccess":28,"references":2497,"isForceReanalyzing":1228},"8da4ad3d-1267-4a4a-b700-e70009769271","2024-10-05T08:02:50.247+00:00","2025-01-12T06:40:17.469+00:00",[],"Clinical-characteristics-of-COVID-19-in-solid-organ-transplant-recipients-following-COVID-19-vaccination-A-multicenter-case-series",{"openalex":2262,"abstract":2264,"title":2267,"keywords":2270,"pm":2272,"doi":2274},{"VOID":2263},"W4200232522",{"VI":2265,"EN":2266},"\u003Cjats:sec>\u003Cjats:title>Đặt vấn đề\u003C\u002Fjats:title>\u003Cjats:p>Các bệnh nhân nhận ghép tạng rắn (SOTR) có phản ứng miễn dịch dịch thể đối với vaccine COVID-19 bị suy giảm và tỷ lệ nhiễm COVID-19 breakthrough vaccine cao hơn so với dân số nói chung. Thông tin về mức độ nghiêm trọng của bệnh COVID-19 ở SOTR với nhiễm COVID-19 breakthrough vaccine còn hạn chế.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Phương pháp\u003C\u002Fjats:title>\u003Cjats:p>Giữa ngày 4 tháng 7 năm 2021 và ngày 21 tháng 6 năm 2021, chúng tôi đã yêu cầu báo cáo ca thông qua danh sách gửi thư của Mạng Lưới Nhiễm Khuẩn Mới (EIN) về nhiễm SARS-CoV-2 sau tiêm vaccine COVID-19 ở SOTR. Thu thập dữ liệu trực tuyến bao gồm thông tin nhân khẩu học của bệnh nhân, thời gian tiêm vaccine COVID-19 và dữ liệu lâm sàng liên quan đến COVID-19. Chúng tôi đã thực hiện phân tích mô tả các yếu tố của bệnh nhân và đánh giá các biến liên quan đến bệnh nghiêm trọng hoặc cần nhập viện.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Kết quả\u003C\u002Fjats:title>\u003Cjats:p>Đã thu thập 66 ca nhiễm SARS-CoV-2 sau khi tiêm vaccine ở SOTR. COVID-19 xảy ra sau liều vaccine thứ hai ở 52 (78,8%) ca, trong đó 43 (82,7%) xảy ra ≥14 ngày sau tiêm vaccine. Có sáu ca tử vong, ba ca xảy ra ở những người đã tiêm đầy đủ (7,0%, \u003Cjats:italic>n\u003C\u002Fjats:italic> = 3\u002F43). Không có sự khác biệt về tỷ lệ bệnh nhân hồi phục sau COVID-19 (70,7% so với 72,2%, \u003Cjats:italic>p\u003C\u002Fjats:italic> = 0.90) giữa những người đã tiêm đầy đủ và một phần. Chúng tôi không phát hiện sự khác biệt nào trong việc nhập viện (60,5% so với 55,6%, \u003Cjats:italic>p\u003C\u002Fjats:italic> = 0.72) hoặc bệnh nghiêm trọng (20,9% so với 33,3%, \u003Cjats:italic>p\u003C\u002Fjats:italic> = 0.30) giữa những người đã tiêm đầy đủ và một phần.","\u003Cjats:sec>\u003Cjats:title>Background\u003C\u002Fjats:title>\u003Cjats:p>Solid organ transplant recipients (SOTR) have diminished humoral immune responses to COVID‐19 vaccination and higher rates of COVID‐19 vaccine breakthrough infection than the general population. Little is known about COVID‐19 disease severity in SOTR with COVID‐19 vaccine breakthrough infections.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods\u003C\u002Fjats:title>\u003Cjats:p>Between 4\u002F7\u002F21 and 6\u002F21\u002F21, we requested case reports via the Emerging Infections Network (EIN) listserv of SARS‐CoV‐2 infection following COVID‐19 vaccination in SOTR. Online data collection included patient demographics, dates of COVID‐19 vaccine administration, and clinical data related to COVID‐19. We performed a descriptive analysis of patient factors and evaluated variables contributing to critical disease or need for hospitalization.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>Sixty‐six cases of SARS‐CoV‐2 infection after vaccination in SOTR were collected. COVID‐19 occurred after the second vaccine dose in 52 (78.8%) cases, of which 43 (82.7%) occurred ≥14 days post‐vaccination. There were six deaths, three occurring in fully vaccinated individuals (7.0%, \u003Cjats:italic>n\u003C\u002Fjats:italic> = 3\u002F43). There was no difference in the percentage of patients who recovered from COVID‐19 (70.7% vs. 72.2%, \u003Cjats:italic>p\u003C\u002Fjats:italic> = .90) among fully and partially vaccinated individuals. We did not identify any differences in hospitalization (60.5% vs. 55.6%, \u003Cjats:italic>p\u003C\u002Fjats:italic> = .72) or critical disease (20.9% vs. 33.3%, \u003Cjats:italic>p\u003C\u002Fjats:italic> = .30) among those who were fully versus partially vaccinated.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>SOTR vaccinated against COVID‐19 can still develop severe, and even critical, COVID‐19 disease. Two doses of mRNA COVID‐19 vaccine may be insufficient to protect against severe disease and mortality in SOTR. Future studies to define correlates of protection in SOTR are needed.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":2268,"VI":2269},"Clinical characteristics of COVID‐19 in solid organ transplant recipients following COVID‐19 vaccination: A multicenter case series","Đặc điểm lâm sàng của COVID-19 ở người nhận ghép tạng rắn sau khi tiêm vaccine COVID-19: Một loạt ca đa trung tâm",{"VI":2271},"COVID-19, vaccine, ghép tạng rắn, phản ứng miễn dịch",{"VOID":2273},"34905269",{"VOID":2275},"10.1111\u002Ftid.13774",[31],[30],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Ftid.13774",[2280,2299,2318,2337,2354,2371,2390,2409,2426],{"id":2281,"sortIndex":32,"researcher":28,"roles":2282,"affiliations":2283,"properties":2292,"displayName":2296,"givenName":28,"familyName":28},"27e0337d-5f41-4bb4-8a79-f83ade96daea",[],[2284],{"id":2285,"sortIndex":32,"affiliation":2286,"properties":28},"0434be95-e736-45ee-a6ad-cb20c520f104",{"id":2285,"createTime":28,"updateTime":28,"relativeEntities":2287,"slug":28,"properties":2288,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2291,"statistic":28},[],{"title":2289},{"EN":2290},"Institute of Human Virology, Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, Maryland, USA",[],{"orcid":2293,"title":2295,"openalex":2297},{"VOID":2294},"https:\u002F\u002Forcid.org\u002F0000-0002-5116-0042",{"EN":2296},"Kapil Saharia",{"VOID":2298},"A5004218416",{"id":2300,"sortIndex":40,"researcher":28,"roles":2301,"affiliations":2302,"properties":2311,"displayName":2315,"givenName":28,"familyName":28},"8452e80c-2c19-4376-83ea-6f209bd635ad",[],[2303],{"id":2304,"sortIndex":32,"affiliation":2305,"properties":28},"aee822bc-ccd2-440b-8f0f-54ea5a92c544",{"id":2304,"createTime":28,"updateTime":28,"relativeEntities":2306,"slug":28,"properties":2307,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2310,"statistic":28},[],{"title":2308},{"EN":2309},"Department of Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA",[],{"orcid":2312,"title":2314,"openalex":2316},{"VOID":2313},"https:\u002F\u002Forcid.org\u002F0000-0002-7761-1163",{"EN":2315},"Shweta Anjan",{"VOID":2317},"A5041410897",{"id":2319,"sortIndex":123,"researcher":28,"roles":2320,"affiliations":2321,"properties":2330,"displayName":2334,"givenName":28,"familyName":28},"0d6f7f82-6f4b-452b-bd54-f326f9cc5c1a",[],[2322],{"id":2323,"sortIndex":32,"affiliation":2324,"properties":28},"299eda46-37e1-45eb-a399-341229c9ccc4",{"id":2323,"createTime":28,"updateTime":28,"relativeEntities":2325,"slug":28,"properties":2326,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2329,"statistic":28},[],{"title":2327},{"EN":2328},"Department of Medicine, Division of Infectious Diseases, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA",[],{"orcid":2331,"title":2333,"openalex":2335},{"VOID":2332},"https:\u002F\u002Forcid.org\u002F0000-0001-8629-3622",{"EN":2334},"Judy A. 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Transplant",{},{"id":28,"text":2559,"url":28,"identifiers":2560},"Tenforde MW, 2021, Effectiveness of SARS‐CoV‐2 mRNA vaccines for preventing COVID‐19 hospitalization in the United States, Clin Infect Dis",{},{"id":28,"text":2562,"url":28,"identifiers":2563},"10.1016\u002FS0140-6736(21)01358-1",{"doi":2562},{"id":28,"text":2565,"url":28,"identifiers":2566},"10.1056\u002FNEJMoa2108891",{"doi":2565},{"id":28,"text":2568,"url":28,"identifiers":2569},"10.1056\u002FNEJMc2108861",{"doi":2568},{"id":28,"text":2571,"url":28,"identifiers":2572},"10.1056\u002FNEJMc2111462",{"doi":2571},{"id":28,"text":2574,"url":28,"identifiers":2575},"10.7326\u002FL21-0282",{"doi":2574},{"id":28,"text":2577,"url":28,"identifiers":2578},"10.1016\u002FS1473-3099(20)30483-7",{"doi":2577},{"id":28,"text":2580,"url":28,"identifiers":2581},"COVID‐19 Treatment Guidelines Panel. Coronavirus disease 2019 (COVID‐19) treatment guidelines.National Institutes of Health. Accessed September 25 2021.https:\u002F\u002Fwww.covid19treatmentguidelines.nih.gov\u002F",{},{"id":2583,"createTime":2584,"updateTime":2585,"relativeEntities":2586,"slug":2587,"properties":2588,"entityType":975,"verifyStatus":26,"verifyTime":2584,"verifyNote":976,"languages":2604,"translateLanguages":2605,"viewCount":32,"primaryUrl":2606,"fullTextUrl":28,"authors":2607,"publicationType":1132,"publisherRelationship":2659,"citationCount":129,"citationInfo":2708,"publishDate":2711,"publishYear":2709,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":2712,"openAccess":28,"references":2713,"isForceReanalyzing":1228},"1c49e0cf-fa7f-40c6-a108-ffe8301dbbf1","2024-10-10T07:01:25.440+00:00","2025-01-12T06:41:14.351+00:00",[],"The-potential-role-of-lactoferrin-and-derivatives-in-the-management-of-infectious-and-inflammatory-complications-of-hematology-patients-receiving-a-hematopoietic-stem-cell-transplantation",{"mag":2589,"keywords":2591,"openalex":2592,"abstract":2594,"title":2597,"pm":2600,"doi":2602},{"VOID":2590},"2101792952",{"VI":960},{"VOID":2593},"W2101792952",{"VI":2595,"EN":2596},"\u003Cjats:p>\u003Cjats:bold>Tóm tắt: \u003C\u002Fjats:bold> Lactoferrin ở người là một protein phòng thủ tự nhiên thuộc hệ miễn dịch bẩm sinh, có mặt trong nhiều dịch cơ thể và tiết ra, cũng như trong các hạt thứ cấp của bạch cầu trung tính đa hình. Lactoferrin và các dẫn xuất của nó có chức năng pleiotropic bao gồm hoạt động kháng khuẩn rộng, hoạt động chống khối u, điều hòa sự tăng trưởng và biệt hóa của tế bào, cũng như điều chỉnh phản ứng viêm, miễn dịch thể dịch và tế bào. Đó là lý do vì sao nhiều nghiên cứu đã chú trọng đến hoạt tính trị liệu tiềm năng của các phân tử này trong nhiều môi trường lâm sàng khác nhau, đặc biệt liên quan đến các bệnh truyền nhiễm và tình trạng viêm không kiểm soát. Ở những bệnh nhân mắc bệnh ác tính huyết học được điều trị bằng ghép tế bào gốc tạo máu (HSCT), tỷ lệ morbid và tử vong do nhiễm trùng và viêm không kiểm soát vẫn cao, mặc dù đã có nhiều tiến bộ trong chăm sóc hỗ trợ. Những biến chứng đe dọa đến tính mạng này là kết quả của thiệt hại do chế độ điều trị gây ra đối với hàng rào niêm mạc, cũng như hệ thống miễn dịch bẩm sinh và thích ứng, miễn dịch thể dịch và tế bào. Những biến chứng này yêu cầu phải tiếp tục khám phá các phương thức điều trị mới. Mức lactoferrin toàn thân và có thể cả tại chỗ giảm sau khi ghép tế bào gốc tạo máu. Do đó, việc sử dụng lactoferrin, hoặc các dẫn xuất peptide ngắn giữ lại nhóm N-terminal cationic mà thiết yếu cho hoạt động kháng khuẩn và chống viêm, có thể chứng minh là lớp tác nhân đa năng hứa hẹn cho việc quản lý các biến chứng phát sinh từ HSCT.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> Human lactoferrin is a natural defense protein belonging to the innate immune system present in several body fluids and secretions, as well as in the secondary granules of polymorphonuclear neutrophils. Lactoferrin and its derivatives have pleiotropic functions including broad‐spectrum anti‐microbial activity, anti‐tumor activity, regulation of cell growth and differentiation, and modulation of inflammatory as well as humoral and cellular immune responses. This is the reason why much research has addressed the potential therapeutic activity of these molecules in different clinical settings, especially regarding infectious diseases and uncontrolled inflammatory conditions. In patients with hematological malignancies treated with a hematopoietic stem cell transplantation (HSCT), morbidity and mortality due to infections and uncontrolled inflammation remains high, despite many advances in supportive care. These life‐threatening complications are a result of the damage caused by the conditioning regimens to the mucosal barrier, and the innate and adaptive, humoral, and cellular immune defenses. These complications necessitate the continued exploration of new treatment modalities. Systemic and probably local levels of lactoferrin are decreased following HSCT. Therefore, the use of lactoferrin, or short peptide derivatives that retain the cationic N‐terminal moiety that is essential for the anti‐microbial and anti‐inflammatory activity, may prove to be a promising versatile class of agents for managing the complications that arise from HSCT.\u003C\u002Fjats:p>",{"EN":2598,"VI":2599},"The potential role of lactoferrin and derivatives in the management of infectious and inflammatory complications of hematology patients receiving a hematopoietic stem cell transplantation","Vai trò tiềm năng của lactoferrin và các dẫn xuất trong việc quản lý các biến chứng nhiễm trùng và viêm ở bệnh nhân huyết học nhận ghép tế bào gốc tạo máu",{"VOID":2601},"17605731",{"VOID":2603},"10.1111\u002Fj.1399-3062.2007.00260.x",[31],[30],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1399-3062.2007.00260.x",[2608,2627,2642],{"id":2609,"sortIndex":32,"researcher":28,"roles":2610,"affiliations":2611,"properties":2620,"displayName":2624,"givenName":28,"familyName":28},"caac1f5e-28bc-444f-bb84-fd39d81401c0",[],[2612],{"id":2613,"sortIndex":32,"affiliation":2614,"properties":28},"9cabb9f4-4002-411b-8dc9-a262acc6b79e",{"id":2613,"createTime":28,"updateTime":28,"relativeEntities":2615,"slug":28,"properties":2616,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2619,"statistic":28},[],{"title":2617},{"VI":2618},"Department of Hematology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands",[],{"orcid":2621,"title":2623,"openalex":2625},{"VOID":2622},"https:\u002F\u002Forcid.org\u002F0000-0002-7002-9701",{"EN":2624},"Walter J. 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GH, 1999, Neutralization of endotoxin in vitro and in vivo by a human lactoferrin‐derived peptide, Infect Immunol, 67, 1353, 10.1128\u002FIAI.67.3.1353-1358.1999",{"doi":2936},"10.1128\u002FIAI.67.3.1353-1358.1999",{"id":28,"text":2938,"url":28,"identifiers":2939},"Lupetti A, 2003, 99mTc‐antimicrobial peptides, promising candidates for infection imaging, 47, 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lao, bệnh bạch cầu cấp myelogenous, ghép tế bào gốc, bệnh nhân suy giảm miễn dịch",{"VOID":2958},"W2119074141",{"VI":2960,"EN":2961},"\u003Cjats:p>\u003Cjats:bold>Tóm tắt: \u003C\u002Fjats:bold> Chúng tôi báo cáo trường hợp của một phụ nữ Nhật Bản 43 tuổi mắc bệnh bạch cầu cấp myelogenous, người đã trải qua 2 lần ghép tế bào gốc dây rốn không liên quan (UCBT), dẫn đến bệnh lao (TB) lan tỏa dẫn đến tử vong. Bệnh nhân không đạt được tình trạng thuyên giảm mặc dù đã tiến hành hóa trị liệu tích cực, và sau đó đã thực hiện UCBT với một chế độ điều trị chuẩn. Tuy nhiên, việc cấy ghép không thành công. Năm mươi ngày sau lần UCBT đầu tiên, bệnh nhân đã trải qua lần UCBT thứ hai với một chế độ điều trị giảm cường độ. Cô đã phát triển một phản ứng miễn dịch trước cấy ghép, phản ứng tốt với prednisolon, và việc cấy ghép đã được ghi nhận. Tuy nhiên, 50 ngày sau UCBT thứ hai, bệnh nhân xuất hiện sốt cao và phát triển viêm phổi mặc dù đã điều trị kháng sinh và kháng nấm. Sau đó, \u003Cjats:italic>Mycobacterium tuberculosis\u003C\u002Fjats:italic> được phát hiện trong các mẫu nuôi cấy máu và các mẫu rửa phế quản phế nang, cho thấy bệnh lao lan tỏa. Mặc dù đã điều trị lao, cô đã tử vong vào ngày 85. TB nên luôn được coi là một chẩn đoán có thể trong quá trình điều trị cho những bệnh nhân suy giảm miễn dịch có sốt.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> Here we report the case of a 43‐year‐old Japanese woman with acute myelogenous leukemia who underwent 2 unrelated cord blood transplantations (UCBT), terminating in fatal disseminated tuberculosis (TB). The patient did not achieve remission despite intensive chemotherapy, and subsequently underwent UCBT with a standard conditioning regimen. However, engraftment was not achieved. Fifty days after the first UCBT, the patient underwent a second UCBT with a reduced‐intensity conditioning regimen. She developed a pre‐engraftment immune reaction, which responded well to prednisolone, and engraftment was documented. However, 50 days after the second UCBT, the patient presented with high fever and developed pneumonia despite antibiotic and antifungal treatments. Thereafter, \u003Cjats:italic>Mycobacterium tuberculosis\u003C\u002Fjats:italic> was detected in blood cultures and specimens of bronchoalveolar lavage, thus indicating disseminated TB. Despite anti‐tuberculous treatment, she died on day 85. TB should always be considered as a possible diagnosis when treating febrile immunocompromised patients.\u003C\u002Fjats:p>",{"EN":2963,"VI":2964},"Disseminated tuberculosis following second unrelated cord blood transplantation for acute myelogenous leukemia","Bệnh lao lan tỏa sau khi ghép tế bào gốc không liên quan lần thứ hai cho bệnh bạch cầu cấp 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Chúng tôi mô tả một trường hợp bệnh lao kháng đa thuốc ở một bệnh nhân nhận ghép tủy xương đồng loại với phản ứng tốt đối với liệu pháp điều trị hàng thứ hai.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> Multidrug‐resistant tuberculosis (TB) is an increasing problem worldwide, however only three cases have been previously described in transplant recipients, especially involving lung and heart transplant. We describe a case of multidrug‐resistant TB in an allogenic bone marrow transplant recipient with good response to second‐line therapy.\u003C\u002Fjats:p>",{"EN":3298,"VI":3299},"Multidrug‐resistant tuberculosis in bone marrow transplant recipient","Bệnh lao kháng đa thuốc ở người nhận ghép tủy xương",{"VOID":3301},"15984950",{"VOID":3303},"10.1111\u002Fj.1399-3062.2005.00083.x",[31],[30],"https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fj.1399-3062.2005.00083.x",[3308,3327,3342,3357,3376,3393,3410,3429],{"id":3309,"sortIndex":32,"researcher":28,"roles":3310,"affiliations":3311,"properties":3320,"displayName":3324,"givenName":28,"familyName":28},"7f0aa1dd-cc98-425d-866f-1c7a771e4ae7",[],[3312],{"id":3313,"sortIndex":32,"affiliation":3314,"properties":28},"813c6481-aaaf-44e0-b6b0-4fcd71ffa346",{"id":3313,"createTime":28,"updateTime":28,"relativeEntities":3315,"slug":28,"properties":3316,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3319,"statistic":28},[],{"title":3317},{"EN":3318},"Department of Infectious Diseases, Sanatorio Mitre, Buenos Aires, Argentina",[],{"orcid":3321,"title":3323,"openalex":3325},{"VOID":3322},"https:\u002F\u002Forcid.org\u002F0000-0002-5241-2758",{"EN":3324},"Javier Bermejo",{"VOID":3326},"A5087490208",{"id":3328,"sortIndex":40,"researcher":28,"roles":3329,"affiliations":3330,"properties":3337,"displayName":3339,"givenName":28,"familyName":28},"8a4b6b78-3671-4742-abd1-276723288b9e",[],[3331],{"id":3313,"sortIndex":32,"affiliation":3332,"properties":28},{"id":3313,"createTime":28,"updateTime":28,"relativeEntities":3333,"slug":28,"properties":3334,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3336,"statistic":28},[],{"title":3335},{"EN":3318},[],{"title":3338,"openalex":3340},{"EN":3339},"AG Lescano",{"VOID":3341},"A5048250750",{"id":3343,"sortIndex":123,"researcher":28,"roles":3344,"affiliations":3345,"properties":3352,"displayName":3354,"givenName":28,"familyName":28},"e0fb3e99-7ef6-4559-b360-490cb64b12c3",[],[3346],{"id":3313,"sortIndex":32,"affiliation":3347,"properties":28},{"id":3313,"createTime":28,"updateTime":28,"relativeEntities":3348,"slug":28,"properties":3349,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3351,"statistic":28},[],{"title":3350},{"EN":3318},[],{"title":3353,"openalex":3355},{"EN":3354},"Claudia Salgueira",{"VOID":3356},"A5048079435",{"id":3358,"sortIndex":42,"researcher":28,"roles":3359,"affiliations":3360,"properties":3369,"displayName":3373,"givenName":28,"familyName":28},"0465da8b-8c69-4aa5-9eef-bcf4a5deed6b",[],[3361],{"id":3362,"sortIndex":32,"affiliation":3363,"properties":28},"986f7db4-e1a9-4f7f-87b0-1ef3430fbd0a",{"id":3362,"createTime":28,"updateTime":28,"relativeEntities":3364,"slug":28,"properties":3365,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3368,"statistic":28},[],{"title":3366},{"EN":3367},"Department of Microbiology, Sanatorio Mitre, Buenos Aires, Argentina",[],{"orcid":3370,"title":3372,"openalex":3374},{"VOID":3371},"https:\u002F\u002Forcid.org\u002F0000-0003-3571-2211",{"EN":3373},"Angela Di Martino",{"VOID":3375},"A5053741257",{"id":3377,"sortIndex":45,"researcher":28,"roles":3378,"affiliations":3379,"properties":3386,"displayName":3390,"givenName":28,"familyName":28},"c138c78e-9d6c-47b3-96ce-ff9fbd93a164",[],[3380],{"id":3313,"sortIndex":32,"affiliation":3381,"properties":28},{"id":3313,"createTime":28,"updateTime":28,"relativeEntities":3382,"slug":28,"properties":3383,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":3385,"statistic":28},[],{"title":3384},{"EN":3318},[],{"orcid":3387,"title":3389,"openalex":3391},{"VOID":3388},"https:\u002F\u002Forcid.org\u002F0000-0001-7814-2306",{"EN":3390},"Victoria K. 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V, 1997, Mycobacterial infections following bone marrow transplantation, a 20 year retrospective review, 19, 467",{},{"id":28,"text":3514,"url":28,"identifiers":3515},"10.3201\u002Feid0908.020474",{"doi":3514},{"id":28,"text":3517,"url":28,"identifiers":3518},"10.1086\u002F514084",{"doi":3517},{"id":28,"text":3520,"url":28,"identifiers":3521},"Aita J, 1996, Hospital transmission of multidrug‐resistant Mycobacterium tuberculosis in Rosario, Argentina, Medicina (B Aires), 56, 48",{},{"id":28,"text":3523,"url":28,"identifiers":3524},"Di Perri G, 1998, Fatal primary multidrug‐resistant tuberculosis in a heart transplant recipient, Transpl Int, 11, 305, 10.1007\u002Fs001470050147",{"doi":3525},"10.1007\u002Fs001470050147",{"id":28,"text":3527,"url":28,"identifiers":3528},"10.1016\u002FS1053-2498(02)01189-0",{"doi":3527},{"id":28,"text":3530,"url":28,"identifiers":3531},"Shitrit D, 2004, Multidrug resistant tuberculosis following lung transplantation, treatment with pulmonary resection, 59, 79",{},{"id":3533,"createTime":3534,"updateTime":3535,"relativeEntities":3536,"slug":3537,"properties":3538,"entityType":975,"verifyStatus":26,"verifyTime":3534,"verifyNote":976,"languages":3554,"translateLanguages":3555,"viewCount":32,"primaryUrl":3556,"fullTextUrl":28,"authors":3557,"publicationType":1132,"publisherRelationship":3627,"citationCount":126,"citationInfo":3676,"publishDate":3679,"publishYear":3677,"citationAnalyzeStatus":884,"lastCitationAnalyze":28,"indexDatabases":3680,"openAccess":28,"references":3681,"isForceReanalyzing":1228},"08fbfcde-239e-4ded-8a5d-42437646be8c","2025-01-07T20:20:58.935+00:00","2025-01-12T06:44:02.319+00:00",[],"-i-Pasteurella-multocida-i-septic-shock-following-liver-transplantation-treated-with-drotrecogin-alfa-activated-",{"mag":3539,"keywords":3541,"openalex":3542,"abstract":3544,"title":3547,"pm":3550,"doi":3552},{"VOID":3540},"2069064753",{"VI":960},{"VOID":3543},"W2069064753",{"VI":3545,"EN":3546},"\u003Cjats:p>\u003Cjats:bold>Tóm tắt: \u003C\u002Fjats:bold> Sốc nhiễm trùng nặng và việc tiến triển đến sốc nhiễm trùng trong người nhận ghép tạng có liên quan đến tỷ lệ tử vong cao. Chúng tôi mô tả một trường hợp sốc nhiễm trùng cấp tính ở một bệnh nhân ghép gan do \u003Cjats:italic>Pasteurella multocida\u003C\u002Fjats:italic>, một loại coccobacillus gram âm thường gặp ở mèo và chó nuôi trong nhà. \u003Cjats:italic>P. multocida\u003C\u002Fjats:italic> là nguyên nhân hiếm gặp gây nhiễm khuẩn huyết và chưa được ghi nhận là nguyên nhân gây sốc nhiễm trùng sau khi ghép gan. Ngoài việc điều trị tiêu chuẩn, bệnh nhân đã được quản lý bằng drotrecogin alfa (kích hoạt), một loại thuốc có cơ sở bằng chứng cho thấy cải thiện đáng kể kết quả ở bệnh nhân sốc nhiễm trùng nặng trong quần thể không được ghép tạng. Các yếu tố nguy cơ đã biết, diễn biến lâm sàng, và kết quả của nhiễm trùng nặng liên quan đến \u003Cjats:italic>P. multocida\u003C\u002Fjats:italic> cũng được xem xét một cách ngắn gọn. Trường hợp này minh họa cho nhu cầu mà người nhận ghép tạng và các nhà cung cấp dịch vụ y tế của họ phải cân nhắc cẩn thận về nguy cơ nhiễm trùng nặng liên quan đến tiếp xúc với động vật nuôi trong nhà.\u003C\u002Fjats:p>","\u003Cjats:p>\u003Cjats:bold>Abstract: \u003C\u002Fjats:bold> Severe sepsis and progression to septic shock in solid organ transplant recipients is associated with a high mortality. We describe a fulminant case of septic shock in a liver transplant recipient caused by \u003Cjats:italic>Pasteurella multocida\u003C\u002Fjats:italic>, a gram‐negative coccobacillus most commonly associated with domestic cats and dogs. \u003Cjats:italic>P. multocida\u003C\u002Fjats:italic> is a rare cause of bacteremia and has not been reported as a cause of septic shock following liver transplantation. In addition to standard therapy, the patient was managed with drotrecogin alfa (activated) recombinant activated protein C (APC), an evidence‐based agent that has been shown to significantly improve outcome in severe sepsis in the non‐transplant population. The known risk factors, clinical course, and outcomes of severe infection associated with \u003Cjats:italic>P. multocida\u003C\u002Fjats:italic> are also briefly reviewed. 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