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This study investigated the seroprevalence of HBV and HCV in southern Taiwan. Screening programs were performed from September 1999 to August 2005 for community‐based surveillance of liver disease. A total of 28,797 adults from southern Taiwan, including Kaohsiung City (\u003Cjats:italic>n\u003C\u002Fjats:italic> = 14,036), Kaohsiung County (\u003Cjats:italic>n\u003C\u002Fjats:italic> = 7,713), and Pingtung County (\u003Cjats:italic>n\u003C\u002Fjats:italic> = 7,048) were participated. The mean age was 50.3 ± 14.6 years (range, 20‐97 years), with 41.0% were men. Hepatitis B surface antigen (HBsAg), antibody to HCV (anti‐HCV), and liver function tests were performed. Among the 28,797 adults, the prevalence of HBsAg(+) was 15.1% and that for anti‐HCV(+) was 8.6%. The seroprevalence of HBsAg in Kaohsiung County was 18.2%, which was higher than in Kaohsiung City (14.7%, \u003Cjats:italic>p\u003C\u002Fjats:italic> < 0.001) or Pingtung County (12.5%, \u003Cjats:italic>p\u003C\u002Fjats:italic> < 0.001). The seroprevalence of anti‐HCV in Kaohsiung County was 17.2%, which was higher than in the other regions (Kaohsiung City = 5.8%, \u003Cjats:italic>p\u003C\u002Fjats:italic> < 0.001; Pingtung County = 4.6%, \u003Cjats:italic>p\u003C\u002Fjats:italic> < 0.001). The prevalence of dual HBsAg and anti‐HCV was 1.1% (323 patients). Tzukuan Township in Kaohsiung County was endemic for HBsAg (19.1%, 1,026\u002F5,375 patients), anti‐HCV (22.4%, 1,203\u002F5,375 patients), and dual HBsAg\u002Fanti‐HCV (3.6%, 191\u002F5,375 patients). Subjects with anti‐HCV(+) were older and had higher alanine transaminase levels than their HBsAg(+) counterparts (\u003Cjats:italic>p\u003C\u002Fjats:italic> < 0.001 and \u003Cjats:italic>p\u003C\u002Fjats:italic> < 0.001, respectively). The current study shows the epidemiological characteristics of HBV and HCV infections among adults in southern Taiwan. Viral hepatitis infections remain widely endemic in this region.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>","\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Virus viêm gan B (HBV) và virus viêm gan C (HCV) là những nguyên nhân chính gây ra bệnh gan tại Đài Loan và có ảnh hưởng lớn đến sức khỏe của đất nước này. Nghiên cứu này đã điều tra tỷ lệ huyết thanh của HBV và HCV tại Đài Nam. Các chương trình sàng lọc đã được thực hiện từ tháng 9 năm 1999 đến tháng 8 năm 2005 nhằm giám sát bệnh gan dựa trên cộng đồng. Tổng cộng có 28.797 người lớn từ Đài Nam tham gia, bao gồm Thành phố Cao Hùng (n = 14.036), Huyện Cao Hùng (n = 7.713) và Huyện Bình Đông (n = 7.048). Tuổi trung bình là 50,3 ± 14,6 năm (khoảng 20–97 năm), trong đó 41,0% là nam giới. Các xét nghiệm kháng nguyên bề mặt viêm gan B (HBsAg), kháng thể HCV (anti-HCV) và xét nghiệm chức năng gan đã được thực hiện. Trong số 28.797 người lớn, tỷ lệ HBsAg(+) là 15,1% và tỷ lệ anti-HCV(+) là 8,6%. Tỷ lệ huyết thanh của HBsAg ở Huyện Cao Hùng là 18,2%, cao hơn so với Thành phố Cao Hùng (14,7%, p \u003C 0,001) hoặc Huyện Bình Đông (12,5%, p \u003C 0,001). Tỷ lệ huyết thanh của anti-HCV ở Huyện Cao Hùng là 17,2%, cao hơn so với các khu vực khác (Thành phố Cao Hùng = 5,8%, p \u003C 0,001; Huyện Bình Đông = 4,6%, p \u003C 0,001). Tỷ lệ đồng nhiễm HBsAg và anti-HCV là 1,1% (323 bệnh nhân). Thị trấn Tzukuan ở Huyện Cao Hùng có tỷ lệ nhiễm HBsAg cao (19,1%, 1.026\u002F5.375 bệnh nhân), anti-HCV (22,4%, 1.203\u002F5.375 bệnh nhân) và đồng nhiễm HBsAg\u002Fanti-HCV (3,6%, 191\u002F5.375 bệnh nhân). Các đối tượng có anti-HCV(+) có tuổi cao hơn và có mức alanine transaminase cao hơn so với những người có HBsAg(+) (p \u003C 0,001 và p \u003C 0,001 tương ứng). Nghiên cứu hiện tại cho thấy những đặc điểm dịch tễ học của nhiễm HBV và HCV ở người lớn tại Đài Nam. Nhiễm viêm gan virus vẫn còn phổ biến tại khu vực này.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":112,"VI":113},"Viral Hepatitis Infections in Southern Taiwan: A Multicenter Community‐based Study","Nhiễm Virus Viêm Gan ở Đài Nam: Nghiên Cứu Dựa Trên Cộng Đồng Đa Trung Tâm",{"VOID":115},"20837342",{"VOID":117},"10.1016\u002Fs1607-551x(10)70073-5","PUBLICATION","VERIFIED","2024-09-19T02:31:29.129+00:00","Auto 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46\n10.1016\u002FS0015-0282(16)58320-4\n10.1016\u002Fj.fertnstert.2014.01.029\n10.1055\u002Fs-2007-970048\n10.1016\u002Fj.fertnstert.2013.06.013\n10.1016\u002Fj.fertnstert.2010.10.014\nCohen A., 2014, Methotrexate success rates in progressing ectopic pregnancies: a reappraisal, Am J Obstet Gynecol, 211, 128, 10.1016\u002Fj.ajog.2014.03.043\n10.1016\u002Fj.ijgo.2011.09.023\n10.1016\u002FS0020-7292(99)00114-9\n10.1002\u002Fuog.9\n10.1007\u002Fs00404-014-3593-x\n10.1016\u002Fj.fertnstert.2006.10.007\n10.1016\u002Fj.fertnstert.2008.07.1775\n10.1016\u002Fj.ejogrb.2014.05.033\n10.1016\u002FS0301-2115(01)00480-8\n10.1016\u002Fj.fertnstert.2006.11.138\nUstunyurt E., 2013, Role of initial and day‐4 human chorionic gonadotropin levels in predicting the outcome of single‐dose methotrexate treatment in women with tubal EP, Gynecol Obstet, 288, 1149\nCelik E., 2013, Assessment of early decline in the percentage of β‐hCG values between days 0 and 4 after methotrexate therapy in ectopic pregnancy for the prediction of treatment success, J Turk Ger Gynecol Assoc, 14, 125, 10.5152\u002Fjtgga.2013.50133\n10.1016\u002Fj.fertnstert.2014.08.019\n10.1111\u002Fajo.12257",{"EN":642},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Our aim was to evaluate the relationship between the success of methotrexate treatment and β‐hCG levels in progressive tubal ectopic pregnancies. We defined a retrospective cohort of 394 progressive tubal ectopic pregnancy patients treated with methotrexate. A single‐dose methotrexate protocol using 50 mg\u002Fm\u003Cjats:sup>2\u003C\u002Fjats:sup> was administered to patients with progressive tubal ectopic pregnancy. Surgery was performed in patients who exhibited signs of acute abdomen due to tubal rupture. Of 394 patients that received methotrexate treatment, 335 (84.6%) responded to medical treatment, while the remaining 59 (15.36%) underwent surgery due to treatment failure. β‐hCG levels in the failure group were significantly higher as compared with the success group at Day 1, Day 4, and Day 7 (2116 ± 3157 vs. 4178 ± 3422, 2062 ± 3551 vs. 4935 ± 4103, and 1532 ± 3007 vs. 3900 ± 4783, respectively). The receiver operating characteristics curve for β‐hCG levels at Day 1 was 0.738, with a cutoff value of 1418 mIU\u002FmL, while sensitivity and specificity values reached the optimum for treatment success (83.1% and 59.4%, respectively). Medical treatment with methotrexate achieved an 85.02% success rate for the treatment of progressive tubal ectopic pregnancy, while success rates for medical treatment decreased significantly when initial β‐hCG levels were >1418 mIU\u002FmL.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":644},"Methotrexate treatment in progressive tubal ectopic pregnancies and hCG‐related clinicosurgical implications",{"VOID":646},"10.1016\u002Fj.kjms.2016.05.004","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X16300705",[649,665,677,689,701,713,728,740],{"id":650,"sortIndex":39,"researcher":18,"roles":651,"affiliations":653,"properties":662},"9b94f384-20ed-48b6-a92d-34dc8d67026c",[652],"AUTHOR",[654],{"id":18,"sortIndex":19,"affiliation":655,"properties":18},{"id":656,"createTime":657,"updateTime":657,"relativeEntities":658,"slug":18,"properties":659,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"9fc5083f-85c9-4559-8a9d-fd427ea26c58","2023-12-11T13:29:22.890+00:00",[],{"title":660},{"VI":661},"Department of Obstetrics and Gynecology, Tepecik Education and Research Hospital, Gaziler Street, Izmir, Turkey",{"title":663},{"VI":664},"Cüneyt E. 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Ekin",{"url":647,"publisher":753,"properties":775},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":754,"slug":10,"properties":755,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":758,"manageAffiliations":759,"indexDatabases":760,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":756,"title":757},{"VOID":13},{"EN":15},[],[],[761,768],{"id":73,"indexDatabase":762,"url":86,"indexYears":87,"academicFieldIds":767,"indexDatabaseRanking":90},{"id":75,"createTime":76,"updateTime":77,"relativeEntities":763,"label":764,"description":765,"key":83,"publicationTags":766,"standard":18},[],{"EN":80,"VI":80},{"EN":80,"VI":82},[85],[89],{"id":54,"indexDatabase":769,"url":69,"indexYears":18,"academicFieldIds":774,"indexDatabaseRanking":18},{"id":56,"createTime":57,"updateTime":58,"relativeEntities":770,"label":771,"description":772,"key":65,"publicationTags":773,"standard":18},[],{"EN":61,"VI":61},{"VI":63,"EN":64},[67,68],[71],{"volume":776,"pages":778},{"VOID":777},"32",{"VOID":779},"317-322","2016-06-01",2016,{"id":783,"createTime":784,"updateTime":785,"relativeEntities":786,"slug":787,"properties":788,"entityType":118,"verifyStatus":119,"verifyTime":785,"verifyNote":121,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":797,"fullTextUrl":18,"authors":798,"publicationType":495,"publisherRelationship":862,"citationCount":18,"citationInfo":18,"publishDate":890,"publishYear":891,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":631},"ac85d973-6f5d-4c25-950a-8cf451e64695","2024-01-10T08:16:51.995+00:00","2025-01-03T23:55:14.711+00:00",[],"Expression-of-Epidermal-Growth-Factor-Receptor-in-Human-Middle-Ear-Cholesteatoma",{"references":789,"abstract":791,"title":793,"doi":795},{"VOID":790},"10.3109\u002F00016488109138508\n10.1038\u002F311414a0\n10.1016\u002F0014-4827(85)90098-9\n10.1007\u002FBF00426583\nErgun S, 1996, Expression of transforming growth factor‐alpha and epidermal growth factor receptor in middle ear cholesteatoma, Am J Otol, 17, 393\n10.1016\u002F0196-0709(93)90044-8\n10.1111\u002F1523-1747.ep12264708\n10.1111\u002Fj.1600-0560.1992.tb01561.x\nUno Y, 1994, Localization of epidermal growth factor receptor (EGFR) in human cholesteatoma — immunohistochemical studies, Otol Jpn, 4, 78\n10.1288\u002F00005537-199303000-00015\nBujia J, 1996, Epidermal growth factor receptor (EGF‐R) in human middle ear cholesteatoma: an analysis of protein production and gene expression, Am J Otol, 17, 203\n10.1111\u002F1523-1747.ep12259731\n10.1001\u002Farchotol.124.3.261\n10.1007\u002Fs004050100315\n10.1080\u002F00016489950181756\nRodeck U, 1997, EGF‐R dependent regulation of keratinocyte survival, J Cell Sci, 110, 113, 10.1242\u002Fjcs.110.2.113\n10.3109\u002F00016489409126081\nShieh TJ, 1999, Evaluation of proliferative activity in middle ear cholesteatoma using proliferating cell nuclear antigen, Kaohsiung J Med Sci, 15, 468\n10.1016\u002FS0194-5998(96)70287-5\nAlbino AP, 1998, Cholesteatoma: a molecular and cellular puzzle, Am J Otol, 19, 7",{"EN":792},"\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Middle ear cholesteatoma is destructive to auditory ossicles and temporal bone, and treatment usually includes surgical removal of all epithelial content in the tympanomastoid cavity. Epidermal growth factor receptor (EGFR) is a 170 kd to 180 kd transmembrane glycoprotein and its distribution density is related to the ability of the keratinocytes to differentiate and their state of differentiation. We used the avidinbiotin complex technique and EGFR monoclonal antibody to evaluate the expression of EGFR in 29 cases of cholesteatoma and 34 samples of normal postauricular skin. Of patients with cholesteatoma, 79% (23 cases) had EGFR‐positive cells in the basal layer, 66% (19 cases) in the parabasal layer, and 62% (18 cases) in the upper layer of the epithelial tissue. Among patients with normal postauricular skin, 85% (29 cases) had EGFR‐positive cells in the basal layer, 79% (27 cases) in the parabasal layer, and 79% (27 cases) in the upper layer of the epithelial tissue. No statistical difference in EGFR expression between each layer of cholesteatoma and postauricular skin was noted. However, there was an intensity gradient of positive EGFR immunoreactivity from the basal to the higher layers in cholesteatoma. Our results showed that the distribution of EGFR in middle ear cholesteatoma is not deranged, but is similar to that in normal skin tissue.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":794},"Expression of Epidermal Growth Factor Receptor in Human Middle Ear Cholesteatoma",{"VOID":796},"10.1016\u002Fs1607-551x(09)70497-8","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X09704978",[799,814,826,838,850],{"id":800,"sortIndex":165,"researcher":18,"roles":801,"affiliations":802,"properties":811},"26b22df5-988b-4321-8a03-4294ec8bfc0e",[652],[803],{"id":18,"sortIndex":19,"affiliation":804,"properties":18},{"id":805,"createTime":806,"updateTime":806,"relativeEntities":807,"slug":18,"properties":808,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"7ae7f09f-df61-457f-836a-47102ec5e92b","2024-01-10T08:16:52.062+00:00",[],{"title":809},{"VI":810},"Department of Otolaryngology, Kaohsiung Medical University, Kaohsiung, Taiwan",{"title":812},{"VI":813},"Ka-Wo Lee",{"id":815,"sortIndex":313,"researcher":18,"roles":816,"affiliations":817,"properties":823},"e2981fe8-0ddf-4b34-8b1b-7bc14f9597ac",[652],[818],{"id":18,"sortIndex":19,"affiliation":819,"properties":18},{"id":805,"createTime":806,"updateTime":806,"relativeEntities":820,"slug":18,"properties":821,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":822},{"VI":810},{"title":824},{"VI":825},"Wen-Rei Kuo",{"id":827,"sortIndex":135,"researcher":18,"roles":828,"affiliations":829,"properties":835},"09edb03d-bf5f-4eee-8b3a-9b2ebdb10bed",[652],[830],{"id":18,"sortIndex":19,"affiliation":831,"properties":18},{"id":805,"createTime":806,"updateTime":806,"relativeEntities":832,"slug":18,"properties":833,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":834},{"VI":810},{"title":836},{"VI":837},"Kuen-Yao Ho",{"id":839,"sortIndex":243,"researcher":18,"roles":840,"affiliations":841,"properties":847},"69d6ac59-e6b5-4560-963d-22ce5cd61f47",[652],[842],{"id":18,"sortIndex":19,"affiliation":843,"properties":18},{"id":805,"createTime":806,"updateTime":806,"relativeEntities":844,"slug":18,"properties":845,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":846},{"VI":810},{"title":848},{"VI":849},"Ling-Feng Wang",{"id":851,"sortIndex":19,"researcher":18,"roles":852,"affiliations":853,"properties":859},"4f34eab2-8337-43aa-a9af-560711d6cd19",[652],[854],{"id":18,"sortIndex":19,"affiliation":855,"properties":18},{"id":805,"createTime":806,"updateTime":806,"relativeEntities":856,"slug":18,"properties":857,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":858},{"VI":810},{"title":860},{"VI":861},"Ying-Che Hsu",{"url":797,"publisher":863,"properties":885},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":864,"slug":10,"properties":865,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":868,"manageAffiliations":869,"indexDatabases":870,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":866,"title":867},{"VOID":13},{"EN":15},[],[],[871,878],{"id":73,"indexDatabase":872,"url":86,"indexYears":87,"academicFieldIds":877,"indexDatabaseRanking":90},{"id":75,"createTime":76,"updateTime":77,"relativeEntities":873,"label":874,"description":875,"key":83,"publicationTags":876,"standard":18},[],{"EN":80,"VI":80},{"EN":80,"VI":82},[85],[89],{"id":54,"indexDatabase":879,"url":69,"indexYears":18,"academicFieldIds":884,"indexDatabaseRanking":18},{"id":56,"createTime":57,"updateTime":58,"relativeEntities":880,"label":881,"description":882,"key":65,"publicationTags":883,"standard":18},[],{"EN":61,"VI":61},{"VI":63,"EN":64},[67,68],[71],{"volume":886,"pages":888},{"VOID":887},"19",{"VOID":889},"497-501","2003-10-01",2003,{"id":893,"createTime":894,"updateTime":895,"relativeEntities":896,"slug":897,"properties":898,"entityType":118,"verifyStatus":119,"verifyTime":895,"verifyNote":121,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":907,"fullTextUrl":18,"authors":908,"publicationType":495,"publisherRelationship":948,"citationCount":18,"citationInfo":18,"publishDate":975,"publishYear":891,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":631},"1b388e86-622b-4da5-9165-a850f97f83ac","2024-02-02T08:52:58.228+00:00","2024-12-28T23:54:28.534+00:00",[],"Intramuscular-Metastasis-of-Cutaneous-Squamous-Cell-Carcinoma-A-Case-Report",{"references":899,"abstract":901,"title":903,"doi":905},{"VOID":900},"10.1056\u002FNEJM200103293441306\n10.1016\u002F0190-9622(92)70144-5\n10.1002\u002F1097-0142(19850901)56:5\u003C1099::AID-CNCR2820560524>3.0.CO;2-R\n10.1016\u002F0007-1226(91)90104-R\nKim CJ, 2001, Metastatic soft tissue squamous cell carcinoma, Am Surg, 67, 111, 10.1177\u002F000313480106700202\n10.1001\u002Farchderm.1952.01530290003001\n10.1016\u002F0190-9622(92)70074-P\n10.1016\u002FS0046-8177(97)90195-7\nSchwickert G, 1995, Correlation of high lactate levels in human cervical cancer with incidence of metastasis, Cancer Res, 55, 4757\n10.1002\u002Fcncr.10362\nTei K, 2002, Role of cell adhesion molecules in tumor angiogenesis induced by cotransplantation of cancer and endothelial cells to nude rats, Cancer Res, 62, 6289\n10.1002\u002F(SICI)1097-0029(19970815)38:4\u003C343::AID-JEMT2>3.0.CO;2-K\nKransdorf MJ, 1993, Imaging of soft tissue tumors, Radiol Clin North Am, 31, 359, 10.1016\u002FS0033-8389(22)02862-7\n10.1001\u002Fjama.1989.03430150065027\n10.1002\u002F(SICI)1097-0215(19990209)80:4\u003C511::AID-IJC5>3.0.CO;2-P",{"EN":902},"\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Cutaneous squamous cell carcinoma (SCC) is a common cancer. Although most patients with primary cutaneous SCC have an excellent prognosis, for those with metastatic disease, the long‐term prognosis is poor. The most common sites of metastasis are regional lymph nodes, lung, liver, brain, skin, and bone. However, metastatic soft tissue SCC from cutaneous lesions is extremely rare, with only two reported cases. We report a case in which the patient had a primary SCC lesion on his left palm in 1986. A second primary SCC on his left forearm was confirmed in 2001, with subsequent metastasis to the proximal muscles and bone invasion in spite of the initial wide excision.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":904},"Intramuscular Metastasis of Cutaneous Squamous Cell Carcinoma: A Case Report",{"VOID":906},"10.1016\u002Fs1607-551x(09)70470-x","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X0970470X",[909,924,936],{"id":910,"sortIndex":19,"researcher":18,"roles":911,"affiliations":912,"properties":921},"03c47cbb-52df-47ce-883a-59f1e2534548",[652],[913],{"id":18,"sortIndex":19,"affiliation":914,"properties":18},{"id":915,"createTime":916,"updateTime":916,"relativeEntities":917,"slug":18,"properties":918,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"e22c8a93-df14-4bf3-9052-1a7956c64db4","2024-02-02T08:52:58.464+00:00",[],{"title":919},{"VI":920},"Division of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Medical University, Kaohsiung, Taiwan",{"title":922},{"VI":923},"Yu-Li Yang",{"id":925,"sortIndex":135,"researcher":18,"roles":926,"affiliations":927,"properties":933},"8a8771d8-e6d3-43b9-89e4-a0f6ce67fad3",[652],[928],{"id":18,"sortIndex":19,"affiliation":929,"properties":18},{"id":915,"createTime":916,"updateTime":916,"relativeEntities":930,"slug":18,"properties":931,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":932},{"VI":920},{"title":934},{"VI":935},"Chung-Sheng Lai",{"id":937,"sortIndex":165,"researcher":18,"roles":938,"affiliations":939,"properties":945},"9bbb300e-407b-4efe-8c7e-1c1a009abd22",[652],[940],{"id":18,"sortIndex":19,"affiliation":941,"properties":18},{"id":915,"createTime":916,"updateTime":916,"relativeEntities":942,"slug":18,"properties":943,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":944},{"VI":920},{"title":946},{"VI":947},"Sin-Daw Lin",{"url":907,"publisher":949,"properties":971},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":950,"slug":10,"properties":951,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":954,"manageAffiliations":955,"indexDatabases":956,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":952,"title":953},{"VOID":13},{"EN":15},[],[],[957,964],{"id":73,"indexDatabase":958,"url":86,"indexYears":87,"academicFieldIds":963,"indexDatabaseRanking":90},{"id":75,"createTime":76,"updateTime":77,"relativeEntities":959,"label":960,"description":961,"key":83,"publicationTags":962,"standard":18},[],{"EN":80,"VI":80},{"EN":80,"VI":82},[85],[89],{"id":54,"indexDatabase":965,"url":69,"indexYears":18,"academicFieldIds":970,"indexDatabaseRanking":18},{"id":56,"createTime":57,"updateTime":58,"relativeEntities":966,"label":967,"description":968,"key":65,"publicationTags":969,"standard":18},[],{"EN":61,"VI":61},{"VI":63,"EN":64},[67,68],[71],{"volume":972,"pages":973},{"VOID":887},{"VOID":974},"188-191","2003-04-01",{"id":977,"createTime":978,"updateTime":979,"relativeEntities":980,"slug":981,"properties":982,"entityType":118,"verifyStatus":119,"verifyTime":979,"verifyNote":121,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":991,"fullTextUrl":18,"authors":992,"publicationType":495,"publisherRelationship":1100,"citationCount":18,"citationInfo":18,"publishDate":1128,"publishYear":1129,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":631},"f5f6f7a2-52ce-4a81-83ee-8abbc1a2ece2","2024-01-28T20:51:55.651+00:00","2024-12-06T23:54:14.313+00:00",[],"Bilateral-simultaneous-facial-palsy-following-scrub-typhus-meningitis-A-case-report-and-literature-review",{"references":983,"abstract":985,"title":987,"doi":989},{"VOID":984},"Kelly D.J., 2009, Scrub typhus: the geographic distribution of phenotypic and genotypic variants of Orientia tsutsugamushi, Clin Infect Dis, 48, S203, 10.1086\u002F596576\n10.1016\u002FS1286-4579(00)01352-6\nLee Y.S., 2006, Epidemiology of scrub typhus in eastern Taiwan, 2000‐2004, Jpn J Infect Dis, 59, 235\n10.1016\u002FS1607-551X(08)70103-7\n10.2310\u002F7070.0124\n10.1111\u002Fj.1525-1497.2006.00466.x\n10.1016\u002FS0001-6519(09)71234-8\nSilva A.A., 2009, Bilateral facial palsy associated with leptospirosis, Braz J Infect Dis, 13, 319, 10.1590\u002FS1413-86702009000400017\nLee C.H., 2007, Coinfection with leptospirosis and scrub typhus in Taiwanese patients, Am J Trop Med Hyg, 77, 525, 10.4269\u002Fajtmh.2007.77.525\n10.1080\u002F00365540310016853\n10.1136\u002Fadc.85.1.54\n10.1080\u002F00365540701266755\n10.1007\u002Fs11845-008-0226-z\nNoad K.B., 1953, The neurological features of Tsutsugamushi fever, with special reference to deafness, Brain, 76, 113, 10.1093\u002Fbrain\u002F76.1.113\n10.1086\u002F498747\nTing K.S., 1992, Brachial plexus neuropathy associated with scrub typhus: report of a case, J Formos Med Assoc, 91, 110\nKim D.E., 2000, Scrub typhus encephalomyelitis with prominent focal neurologic signs, Arch Neurol, 57, 1770, 10.1001\u002Farchneur.57.12.1770\nLee K.L., 2008, Acute transverse myelitis associated with scrub typhus: case report and a review of literatures, Diagn Microbiol Infect Dis, 60, 237, 10.1016\u002Fj.diagmicrobio.2007.09.015\n10.1093\u002Fclinids\u002F24.3.436\n10.3949\u002Fccjm.72.5.398\n10.1016\u002Fj.jemermed.2009.08.016\nTsai C.C., 2010, Levofloxacin versus tetracycline antibiotics for the treatment of scrub typhus, Int J Infect Dis, 14, e62, 10.1016\u002Fj.ijid.2009.03.012",{"EN":986},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Scrub typhus is widely distributed across the Asia‐Pacific region, Taiwan included. The clinical manifestations and complications of scrub typhus vary and the illness ranges in severity from mild to fatal. The etiology of facial nerve palsy varies and infectious agents have been associated with this condition. \u003Cjats:italic>Rickettsiae\u003C\u002Fjats:italic> species have, however, rarely been reported as the causative agents. We report the case of a 49‐year‐old man who had fever, malaise, headache, oligouria and tea‐colored urine. Bilateral pneumonitis, acute renal failure, acalculous cholecystitis and aseptic meningitis were diagnosed after a series of examinations. The patient recovered after doxycycline treatment but he developed bilateral facial palsy during the convalescent phase, which improved after the administration of a steroid. The diagnosis of infection with \u003Cjats:italic>Orientia tsutsugamushi\u003C\u002Fjats:italic> was confirmed by the Taiwan Center of Disease Control and the tests for \u003Cjats:italic>Leptospira\u003C\u002Fjats:italic>, \u003Cjats:italic>Rickettsia typhi\u003C\u002Fjats:italic> and \u003Cjats:italic>Coxiella burnetii\u003C\u002Fjats:italic> were all negative. This case indicates that scrub typhus needs to be included in the differential diagnoses of cases of bilateral and simultaneous facial nerve palsy, particularly in areas where the disease is endemic.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":988},"Bilateral simultaneous facial palsy following scrub typhus meningitis: A case report and literature review",{"VOID":990},"10.1016\u002Fj.kjms.2011.10.003","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X11002269",[993,1021,1050,1062,1081],{"id":994,"sortIndex":243,"researcher":18,"roles":995,"affiliations":996,"properties":1018},"bbe5e04e-d1dc-4ff8-bf95-555d6c17ebc8",[652],[997,1009],{"id":998,"sortIndex":135,"affiliation":999,"properties":1008},"f8049753-9985-4578-a00e-431bc04a5e48",{"id":1000,"createTime":1001,"updateTime":1002,"relativeEntities":1003,"slug":1004,"properties":1005,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"b318e48c-913e-48c0-8433-68a24b0ffa30","2023-12-14T11:55:42.777+00:00","2024-12-27T02:15:15.937+00:00",[],"Graduate-Institute-of-Medicine-College-of-Medicine-Kaohsiung-Medical-University-Kaohsiung-Taiwan",{"title":1006},{"VI":1007},"Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan",{},{"id":18,"sortIndex":19,"affiliation":1010,"properties":18},{"id":1011,"createTime":1012,"updateTime":1012,"relativeEntities":1013,"slug":1014,"properties":1015,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"654e9f89-ced3-4eff-8eee-f451517515e2","2024-04-17T16:30:14.771+00:00",[],"Division-of-Infectious-Diseases-Department-of-Internal-Medicine-Kaohsiung-Medical-University-Hospital-Kaohsiung-Medical-University-Kaohsiung-Taiwan",{"title":1016},{"EN":1017},"Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan",{"title":1019},{"VI":1020},"Po-Liang Lu",{"id":1022,"sortIndex":313,"researcher":18,"roles":1023,"affiliations":1024,"properties":1047},"c08f1cde-beb0-4f3d-86e3-f7da00e9093d",[652],[1025,1035,1042],{"id":1026,"sortIndex":165,"affiliation":1027,"properties":1034},"0a270b23-6434-4e81-8868-faf3501cc548",{"id":1028,"createTime":1029,"updateTime":1029,"relativeEntities":1030,"slug":18,"properties":1031,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"43108115-043e-4f17-822d-0837d92a63f4","2024-02-10T22:27:05.992+00:00",[],{"title":1032},{"VI":1033},"Tropical Medicine Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan",{},{"id":1036,"sortIndex":135,"affiliation":1037,"properties":1041},"4fd7d30c-d0a1-451e-9b20-8dbb7e530440",{"id":1000,"createTime":1001,"updateTime":1002,"relativeEntities":1038,"slug":1004,"properties":1039,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":1040},{"VI":1007},{},{"id":18,"sortIndex":19,"affiliation":1043,"properties":18},{"id":1011,"createTime":1012,"updateTime":1012,"relativeEntities":1044,"slug":1014,"properties":1045,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":1046},{"EN":1017},{"title":1048},{"VI":1049},"Yen-Hsu 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Chen",{"url":991,"publisher":1101,"properties":1123},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1102,"slug":10,"properties":1103,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1106,"manageAffiliations":1107,"indexDatabases":1108,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":1104,"title":1105},{"VOID":13},{"EN":15},[],[],[1109,1116],{"id":73,"indexDatabase":1110,"url":86,"indexYears":87,"academicFieldIds":1115,"indexDatabaseRanking":90},{"id":75,"createTime":76,"updateTime":77,"relativeEntities":1111,"label":1112,"description":1113,"key":83,"publicationTags":1114,"standard":18},[],{"EN":80,"VI":80},{"EN":80,"VI":82},[85],[89],{"id":54,"indexDatabase":1117,"url":69,"indexYears":18,"academicFieldIds":1122,"indexDatabaseRanking":18},{"id":56,"createTime":57,"updateTime":58,"relativeEntities":1118,"label":1119,"description":1120,"key":65,"publicationTags":1121,"standard":18},[],{"EN":61,"VI":61},{"VI":63,"EN":64},[67,68],[71],{"volume":1124,"pages":1126},{"VOID":1125},"27",{"VOID":1127},"573-576","2011-12-01",2011,{"id":1131,"createTime":1132,"updateTime":1133,"relativeEntities":1134,"slug":1135,"properties":1136,"entityType":118,"verifyStatus":119,"verifyTime":1133,"verifyNote":121,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1145,"fullTextUrl":18,"authors":1146,"publicationType":495,"publisherRelationship":1219,"citationCount":18,"citationInfo":18,"publishDate":1247,"publishYear":1248,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":631},"58af1a40-374b-47bc-af38-1e3bb6f4253d","2023-12-27T19:04:59.946+00:00","2025-02-16T23:51:38.728+00:00",[],"Acceleration-of-skin-wound-healing-by-low-dose-indirect-ionizing-radiation-in-male-rats",{"references":1137,"abstract":1139,"title":1141,"doi":1143},{"VOID":1138},"Enoch S., 2008, Basic science of wound healing, Surgery, 26, 31\n10.1016\u002Fj.jss.2008.04.023\nMacKay D., 2003, Nutritional support for wound healing, Altern Med Rev, 8, 359\n10.1016\u002Fj.mehy.2010.07.012\n10.12968\u002Fjowc.2013.22.8.407\n10.1111\u002Fj.1582-4934.2009.00887.x\nKloth L.C., 1996, Promotion of wound healing with electrical stimulation, Adv Wound Care, 9, 42\n10.1016\u002F0041-624X(90)90082-Y\n10.1111\u002Fj.1365-2133.1994.tb13098.x\n10.1007\u002Fs00402-008-0634-6\n10.1590\u002FS0103-64402007000300006\nChen M., 2014, Low‐dose X‐ray irradiation promotes osteoblast proliferation, differentiation and fracture healing, PLoS One, 9\n10.1080\u002F08916930902831738\nLuckey T.D., 2004, Low‐dose irradiation therapy, Radiat Prot Manag, 21, 21\n10.1667\u002FRR1980.1\n10.1016\u002Fj.toxlet.2009.11.011\n10.1016\u002Fj.jphotobiol.2004.08.012\nGál P., 2006, Early changes in the tensile strength and morphology of primary sutured skin wounds in rats, Folia Biol (Praha), 52, 109\nToporcer T., 2006, Mechanical properties of skin wounds after Atropa belladonna application in rats, J Metals, Mater Miner., 16, 25\n10.1089\u002Fwound.2013.0473\nHeydari Nasrabadi M., 2011, Study of cutaneous wound healing in rats treated with Lactobacillus plantarum on days 1, 3, 7, 14 and 21, Afr J Pharm Pharmacol, 5, 2395, 10.5897\u002FAJPP11.568\n10.1177\u002F0022034509359125\nWilliams P.L., 1995, Grays anatomy\nVala I.S., 2010, Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis, PLoS One, 5\nSonveaux P., 2003, Irradiation‐induced angiogenesis through the up‐regulation of the nitric oxide pathway implications for tumor radiotherapy, Cancer Res, 63, 1012\n10.1038\u002Fonc.2013.70\n10.1097\u002FBCR.0B013E318093E44C\n10.1089\u002Fwound.2014.0559\n10.1016\u002Fj.cellimm.2007.02.009\n10.12968\u002Fjowc.2009.18.8.43636\n10.3109\u002F09553002.2013.752595\nDoss M., 2014, Low dose radiation adaptive protection to control neurodegenerative diseases, Dose‐Response, 12, 277, 10.2203\u002Fdose-response.13-030.Doss\n10.1118\u002F1.4881095\n10.2203\u002Fdose-response.06-108.Liu",{"EN":1140},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>A recent hypothesis has revealed that low‐dose irradiation (LDI) with ionizing radiation might have a promoting effect on fracture healing. The aim of this study was to investigate the influence of direct (electron beam) and indirect (gamma‐ray) low‐dose ionizing irradiations on the wound healing process in male rats. In 72 male rats, a full‐thickness wound was incised. The animals were randomly assigned to three groups, each with 24 rats. The first two groups were named IG–I and IG–II and respectively exposed to electron and gamma‐radiations (75 cGy) immediately after the surgical procedure. The third group was considered as the control (CG) and remained untreated. Skin biopsies from the subgroups were collected on days 3, 7, 15, and 21 after the operation and evaluated using histological and biomechanical methods. Data were analyzed by one‐way ANOVA, followed by Tukey's post hoc test using SPSS 20 software. Histological studies of tissues showed that the mean number of fibroblasts, macrophages, blood vessel sections, and neutrophils on the third and seventh days after the surgery in the gamma‐treated group was higher than that in both other groups. In contrast, on day 21, the mean number of mentioned cells in the gamma‐treated group was lower than in the other two groups. In addition, the mean maximum stress value was significantly greater in the gamma‐treated group. Results of this study showed that gamma‐ray irradiation is effective in the acceleration of wound healing.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":1142},"Acceleration of skin wound healing by low‐dose indirect ionizing radiation in male rats",{"VOID":1144},"10.1016\u002Fj.kjms.2017.05.013","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X16303308",[1147,1162,1177,1192,1204],{"id":1148,"sortIndex":135,"researcher":18,"roles":1149,"affiliations":1150,"properties":1159},"da8d36c9-798b-42b0-b7da-e660baa20d96",[652],[1151],{"id":18,"sortIndex":19,"affiliation":1152,"properties":18},{"id":1153,"createTime":1154,"updateTime":1154,"relativeEntities":1155,"slug":18,"properties":1156,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"7d2d789e-4d7d-46df-a1b8-8d8f351d3ef6","2023-12-27T19:04:59.975+00:00",[],{"title":1157},{"VI":1158},"Neurophysiology Research Center, Department of Anatomy, Urmia University of Medical Sciences, Urmia, Iran",{"title":1160},{"VI":1161},"Gholam Hossein Farjah",{"id":1163,"sortIndex":313,"researcher":18,"roles":1164,"affiliations":1165,"properties":1174},"31e4b8f5-9679-4d76-9174-7611f186bbfb",[652],[1166],{"id":18,"sortIndex":19,"affiliation":1167,"properties":18},{"id":1168,"createTime":1169,"updateTime":1169,"relativeEntities":1170,"slug":18,"properties":1171,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"0d73f8d3-3ca6-4c6f-bbb9-e875189df4e5","2023-12-27T19:05:00.074+00:00",[],{"title":1172},{"VI":1173},"Neurophysiology Research Center, Department of Physiology, Urmia University of Medical Sciences, Urmia, Iran",{"title":1175},{"VI":1176},"Behnam Heshmatian",{"id":1178,"sortIndex":243,"researcher":18,"roles":1179,"affiliations":1180,"properties":1189},"a95a0852-f396-4960-846f-d1d0bb1ebba4",[652],[1181],{"id":18,"sortIndex":19,"affiliation":1182,"properties":18},{"id":1183,"createTime":1184,"updateTime":1184,"relativeEntities":1185,"slug":18,"properties":1186,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"fa5ce6e3-1816-43db-9c85-fd83ac403e8d","2023-12-27T19:05:00.049+00:00",[],{"title":1187},{"VI":1188},"Department of Medical Imaging, Urmia University of Medical Sciences, Urmia, Iran",{"title":1190},{"VI":1191},"Hajar Zanjani",{"id":1193,"sortIndex":165,"researcher":18,"roles":1194,"affiliations":1195,"properties":1201},"e0cdbdce-2299-4fea-bbda-47635a9cf2da",[652],[1196],{"id":18,"sortIndex":19,"affiliation":1197,"properties":18},{"id":1183,"createTime":1184,"updateTime":1184,"relativeEntities":1198,"slug":18,"properties":1199,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},[],{"title":1200},{"VI":1188},{"title":1202},{"VI":1203},"Behnam Ghadimi",{"id":1205,"sortIndex":19,"researcher":18,"roles":1206,"affiliations":1207,"properties":1216},"8eec7362-ee1a-42d6-a9fc-3df13bafb7c2",[652],[1208],{"id":18,"sortIndex":19,"affiliation":1209,"properties":18},{"id":1210,"createTime":1211,"updateTime":1211,"relativeEntities":1212,"slug":18,"properties":1213,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"2f49401f-0eb5-4460-935f-977a94b25e1b","2023-12-27T19:04:59.962+00:00",[],{"title":1214},{"VI":1215},"Solid Tumor Research Center, Department of Medical Physics and Imaging, Urmia University of Medical Sciences, Urmia, Iran",{"title":1217},{"VI":1218},"Nasrollah Jabbari",{"url":1145,"publisher":1220,"properties":1242},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1221,"slug":10,"properties":1222,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1225,"manageAffiliations":1226,"indexDatabases":1227,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":1223,"title":1224},{"VOID":13},{"EN":15},[],[],[1228,1235],{"id":73,"indexDatabase":1229,"url":86,"indexYears":87,"academicFieldIds":1234,"indexDatabaseRanking":90},{"id":75,"createTime":76,"updateTime":77,"relativeEntities":1230,"label":1231,"description":1232,"key":83,"publicationTags":1233,"standard":18},[],{"EN":80,"VI":80},{"EN":80,"VI":82},[85],[89],{"id":54,"indexDatabase":1236,"url":69,"indexYears":18,"academicFieldIds":1241,"indexDatabaseRanking":18},{"id":56,"createTime":57,"updateTime":58,"relativeEntities":1237,"label":1238,"description":1239,"key":65,"publicationTags":1240,"standard":18},[],{"EN":61,"VI":61},{"VI":63,"EN":64},[67,68],[71],{"volume":1243,"pages":1245},{"VOID":1244},"33",{"VOID":1246},"385-393","2017-08-01",2017,{"id":1250,"createTime":1251,"updateTime":1252,"relativeEntities":1253,"slug":1254,"properties":1255,"entityType":118,"verifyStatus":119,"verifyTime":1252,"verifyNote":121,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1264,"fullTextUrl":18,"authors":1265,"publicationType":495,"publisherRelationship":1388,"citationCount":18,"citationInfo":18,"publishDate":1416,"publishYear":1417,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":631},"b32069e6-fb0c-4026-975d-ace073839551","2024-01-11T16:10:53.450+00:00","2025-01-07T23:51:38.511+00:00",[],"PGBR-extract-ameliorates-TNF-%CE%B1-induced-insulin-resistance-in-hepatocytes",{"references":1256,"abstract":1258,"title":1260,"doi":1262},{"VOID":1257},"10.1111\u002Fj.1463-1326.2010.01328.x\n10.1038\u002Foby.2003.39\n10.1007\u002Fs12350-011-9362-3\n10.1016\u002Fj.mce.2016.11.010\n10.1002\u002Fjsfa.7600\n10.2337\u002Fdb08-1361\n10.1271\u002Fbbb.68.444\n10.1039\u002FC4FO01194E\n10.3164\u002Fjcbn.14-50\n10.3164\u002Fjcbn.15-117\n10.1155\u002F2016\u002F4801418\n10.3389\u002Ffphar.2014.00230\n10.4049\u002Fjimmunol.1401149\n10.1021\u002Fjf200651c\n10.1016\u002Fj.jnutbio.2013.09.001\n10.2337\u002Fdb07-0763\n10.3390\u002Fnu5020455\n10.1016\u002Fj.jep.2006.10.015\n10.1111\u002Fj.2040-1124.2012.00208.x\n10.1371\u002Fjournal.pone.0127388\n10.3892\u002Fmmr.2013.1714\n10.4239\u002Fwjd.v5.i5.697\n10.3390\u002Fnu7085292\n10.1016\u002Fj.peptides.2013.05.010\n10.1016\u002Fj.bbadis.2013.05.017\n10.3892\u002Fijmm.2012.1158\n10.1038\u002Fcddis.2013.228\n10.1210\u002Fme.16.4.873\n10.1210\u002Fen.2006-1441\nRemacle‐Bonnet M.M., 2000, Insulin‐like growth factor‐I protects colon cancer cells from death factor‐induced apoptosis by potentiating tumor necrosis factor alpha‐induced mitogen‐activated protein kinase and nuclear factor kappaB signaling pathways, Cancer Res, 60, 2007\nIto Y., 2013, GABA type B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance, and hypothalamic inflammation in male mice on a high‐fat diet, J Neurosci, 33, 17166, 10.1523\u002FJNEUROSCI.0897-13.2013",{"EN":1259},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Pre‐germinated brown rice (PGBR) could ameliorate metabolic syndrome, however, not much research estimates the effect of PGBR extract on insulin resistance. The aim of this study is to examine the effects of PGBR extract in TNF‐α induced insulin resistance. HepG2 cells, hepatocytes, were cultured in DMEM medium and added with 5 μM insulin or with insulin and 30 ng\u002Fml TNF‐α or with insulin, TNF‐α and PGBR extract (50, 100, 300 μg\u002Fml). The glucose levels of the medium were decreased by insulin, demonstrating insulin promoted glucose uptake into cell. However, TNF‐α inhibited glucose uptake into cells treated with insulin. Moreover, insulin increased the protein expressions of AMP‐activated protein kinase (AMPK), insulin receptor substrate‐1 (IRS‐1), phosphatidylinositol‐3‐kinase‐α (PI3K‐α), serine\u002Fthreonine kinase PI3K‐linked protein kinase B (Akt\u002FPKB), glucose transporter‐2 (GLUT‐2), glucokinase (GCK), peroxisome proliferator activated receptor‐α (PPAR‐α) and PPAR‐γ. TNF‐α activated p65 and MAPKs (JNK1\u002F2 and ERK1\u002F2) which worsened the expressions of AMPK, IRS‐1, PI3K‐α, Akt\u002FPKB, GLUT‐2, GCK, glycogen synthase kinase‐3 (GSK‐3), PPAR‐α and PPAR‐γ. Once this relationship was established, we added PGBR extract to cell with insulin and TNF‐α. We found glucose levels of medium were lowered and that the protein expressions of AMPK, IRS‐1, PI3K‐α, Akt\u002FPKB, GLUT‐2, GCK, GSK‐3, PPAR‐α, PPAR‐γ and p65, JNK1\u002F2 were also recovered. In conclusion, this study found that TNF‐α inhibited insulin stimulated glucose uptake and aggravated related proteins expressions, suggesting that it might cause insulin resistance. PGBR extract was found to ameliorate this TNF‐α induced insulin resistance, suggesting that it might be used in the future to help control insulin resistance.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":1261},"PGBR extract ameliorates TNF‐α induced insulin resistance in hepatocytes",{"VOID":1263},"10.1016\u002Fj.kjms.2017.08.009","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X17303078",[1266,1283,1298,1315,1342,1359,1376],{"id":1267,"sortIndex":243,"researcher":18,"roles":1268,"affiliations":1269,"properties":1280},"7e7984be-5f50-41e9-9b2d-ae3f301b8ad4",[652],[1270],{"id":18,"sortIndex":19,"affiliation":1271,"properties":18},{"id":1272,"createTime":1273,"updateTime":1274,"relativeEntities":1275,"slug":1276,"properties":1277,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"0362fa2e-cd9a-4a69-88fc-c33b3ce26451","2023-12-11T17:34:12.255+00:00","2025-06-11T16:43:43.002+00:00",[],"Department-of-Food-Science-and-Nutrition-Meiho-University-Pingtung-Taiwan",{"title":1278},{"VI":1279},"Department of Food Science and Nutrition, Meiho University, Pingtung, Taiwan",{"title":1281},{"VI":1282},"Hui-Li Lin",{"id":1284,"sortIndex":165,"researcher":18,"roles":1285,"affiliations":1286,"properties":1295},"67677c51-3996-4b92-ab4a-f8f0cb66d072",[652],[1287],{"id":18,"sortIndex":19,"affiliation":1288,"properties":18},{"id":1289,"createTime":1290,"updateTime":1290,"relativeEntities":1291,"slug":18,"properties":1292,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"9a425a6f-cbd1-43e2-8f22-13dc49ffb007","2024-01-11T16:08:13.094+00:00",[],{"title":1293},{"VI":1294},"Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan",{"title":1296},{"VI":1297},"Jin-Bor 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Taiwan",{"id":1330,"sortIndex":135,"affiliation":1331,"properties":1338},"3eaf2a4f-648e-4557-b0a7-2112e1dfb3ce",{"id":1332,"createTime":1333,"updateTime":1333,"relativeEntities":1334,"slug":18,"properties":1335,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"1f5017dc-6769-4ffe-a3c9-8dbe2058ba8c","2023-12-30T01:13:38.066+00:00",[],{"title":1336},{"VI":1337},"Institute of Biotechnology, National Cheng Kung University, Tainan, Taiwan",{},{"title":1340},{"VI":1341},"Shyh-Yu 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N.P., 2014, Principles for developing animal models of military PTSD, Eur J Psychotraumatol, 14, 5\n10.1016\u002Fj.neuropharm.2011.07.004\n10.1016\u002Fj.psyneuen.2012.02.007\n10.1196\u002Fannals.1314.014\n10.1016\u002Fj.euroneuro.2008.04.009\n10.1080\u002F10253890701768613\nZeller W., 1998, Refinement of blood sampling from sublingual vein of rats, Lab Anim, 32, 69, 10.1258\u002F002367798780599910\n10.1523\u002FJNEUROSCI.0736-05.2005\n10.1086\u002F508828\n10.1016\u002Fj.encep.2011.12.003\nDucrocq F., 2001, Post‐traumatic stress, post‐traumatic depression and major depressive episode: literature, Encephale, 27, 159\n10.1037\u002Ffam0000163\n10.1007\u002Fs11064-011-0660-6\nHarvey B.H., 2004, Stress‐restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus, Psychopharmacology (Berl), 175, 494\n10.1016\u002FS0006-8993(03)03033-6\n10.1111\u002Fj.1600-0447.2006.00801.x\n10.1097\u002F00004583-200108000-00013\n10.1097\u002F01.psy.0000188566.35902.e7\n10.1016\u002Fj.biopsych.2003.11.018\n10.1016\u002Fj.jpsychires.2010.11.016\n10.1016\u002FS0079-6123(07)67011-3\n10.1016\u002Fj.neuroscience.2007.05.041",{"EN":1428},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>This study was conducted to explore the effects of specific psychosocial paradigm on predator animal posttraumatic stress model and to test the hypothesis that psychosocially stressed rats would exibit abnormal levels of cortisol and a larger suppression of cortisol levels after the application of dexamethasone. Animals were divided in two groups: experimental and control groups. The experimental group was exposed to two types of stressors: acute immobilization stress, and combined predator stress and daily social stress with application of dexamethasone. Blood sampling was performed at three different times. We found statistically significant results after analyzing the differences between cortisol levels in different times of blood sampling in the group of animals exposed to stress with dexamethasone application. Statistical significance was found when we compared the experimental group with the control group in terms of elevated cortisol levels during blood sampling after stress paradigm exposition. Many significant disruptions in the functioning of the hypothalamic–pituitary–adrenal axis were observed, such as decrease in basal cortisol levels and enhanced dexamethasone‐induced inhibition of cortisol levels. These findings are important because their impact can translate to human individuals with posttraumatic stress disorder, which is the most important role of every animal model in research.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":1430},"Glucocorticoid levels after exposure to predator odor and chronic psychosocial stress with dexamethasone application in rats",{"VOID":1432},"10.1016\u002Fj.kjms.2016.04.011","2025-01-15T23:47:37.417+00:00","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X16300328",[1436,1453,1465,1480,1495,1507,1522],{"id":1437,"sortIndex":39,"researcher":18,"roles":1438,"affiliations":1439,"properties":1450},"96694e89-d0fd-4a6b-90b2-ac5d5076a4ee",[652],[1440],{"id":18,"sortIndex":19,"affiliation":1441,"properties":18},{"id":1442,"createTime":1443,"updateTime":1444,"relativeEntities":1445,"slug":1446,"properties":1447,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"056814d8-f104-4fbf-bbdb-4fe589bc9b3e","2023-12-06T07:15:55.017+00:00","2025-06-11T18:35:01.911+00:00",[],"Institute-of-Anatomy-Medical-Faculty-University-of-Belgrade-Belgrade-Serbia",{"title":1448},{"VI":1449},"Institute of Anatomy, Medical Faculty, University of Belgrade, Belgrade, Serbia",{"title":1451},{"VI":1452},"Branislav 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Petricevic",{"id":1523,"sortIndex":50,"researcher":18,"roles":1524,"affiliations":1525,"properties":1534},"f1df7b81-9e61-49e4-88e6-50de113fdf52",[652],[1526],{"id":18,"sortIndex":19,"affiliation":1527,"properties":18},{"id":1528,"createTime":1529,"updateTime":1529,"relativeEntities":1530,"slug":18,"properties":1531,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"aa0547f1-5604-45cc-a4d8-b4b7a6f58127","2023-12-06T07:15:55.005+00:00",[],{"title":1532},{"VI":1533},"Orthopaedic Clinic, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia",{"title":1535},{"VI":1536},"Branislav Starcevic",{"url":1434,"publisher":1538,"properties":1560},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1539,"slug":10,"properties":1540,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1543,"manageAffiliations":1544,"indexDatabases":1545,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":1541,"title":1542},{"VOID":13},{"EN":15},[],[],[1546,1553],{"id":73,"indexDatabase":1547,"url":86,"indexYears":87,"academicFieldIds":1552,"indexDatabaseRanking":90},{"id":75,"createTime":76,"updateTime":77,"relativeEntities":1548,"label":1549,"description":1550,"key":83,"publicationTags":1551,"standard":18},[],{"EN":80,"VI":80},{"EN":80,"VI":82},[85],[89],{"id":54,"indexDatabase":1554,"url":69,"indexYears":18,"academicFieldIds":1559,"indexDatabaseRanking":18},{"id":56,"createTime":57,"updateTime":58,"relativeEntities":1555,"label":1556,"description":1557,"key":65,"publicationTags":1558,"standard":18},[],{"EN":61,"VI":61},{"VI":63,"EN":64},[67,68],[71],{"volume":1561,"pages":1562},{"VOID":777},{"VOID":1563},"235-240","2016-05-01",{"id":1566,"createTime":1567,"updateTime":1568,"relativeEntities":1569,"slug":1570,"properties":1571,"entityType":118,"verifyStatus":119,"verifyTime":1568,"verifyNote":121,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"primaryUrl":1580,"fullTextUrl":18,"authors":1581,"publicationType":495,"publisherRelationship":1651,"citationCount":18,"citationInfo":18,"publishDate":1679,"publishYear":1680,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":631},"446e472b-5c36-4b8e-b370-6328600ebaac","2023-12-06T12:04:49.798+00:00","2025-02-23T23:45:49.511+00:00",[],"Midterm-renal-functions-following-acute-renal-infarction",{"references":1572,"abstract":1574,"title":1576,"doi":1578},{"VOID":1573},"Domanovits H., 1999, Acute renal infarction: Clinical characteristics of 17 patients, Medicine, 78, 368, 10.1097\u002F00005792-199911000-00004\nYun E.J., 2005, Urological emergencies: a practical guide, 171, 10.1385\u002F1-59259-886-2:171\n10.1016\u002Fj.ajem.2006.06.010\n10.7326\u002F0003-4819-89-4-477\n10.1097\u002F01.md.0000141097.08000.99\n10.1016\u002FS0720-048X(01)00476-4\n10.7326\u002F0003-4819-130-6-199903160-00002\nGasparini M., 1992, Renal artery embolism: clinical features and therapeutic options, J Urol, 147, 567, 10.1016\u002FS0022-5347(17)37308-1\n10.2215\u002FCJN.05570612\nKorzets Z., 2002, The clinical spectrum of acute renal infarction, Isr Med Assoc J, 4, 781\n10.1016\u002FS0016-5085(00)70183-1\n10.1148\u002Fradiology.199.3.8637978\nBraun D.R., 1995, Idiopathic renal infarction, Urology, 45, 142, 10.1016\u002FS0090-4295(95)97594-2\nMoyer J.D., 1973, Conservative management of renal artery embolus, J Urol, 109, 138, 10.1016\u002FS0022-5347(17)60373-2\n10.3109\u002F0886022X.2014.947514",{"EN":1575},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>The aim of this study was to explore clinical features of renal infarction (RI) that may have a role in diagnosis and treatment in our patient cohort and provide data on midterm renal functions. Medical records of patients with diagnosis of acute RI, established by contrast enhanced computed tomography (CT) and at least 1 year follow‐up data, who were hospitalized in our clinic between 1998 and 2012 were retrospectively reviewed; including descriptive data, clinical signs and symptoms, etiologic factors, laboratory findings, and prescribed treatments. Patients with solitary infarct were treated with acetylsalicylic acid (ASA) only, whereas patients with atrial fibrillation (AF) or multiple or global infarct were treated with anticoagulants. Estimated Glomerular Filtration Rate (eGFR) referring to renal functions was determined by the Modification of Diet in Renal Disease (MDRD) formula. Twenty‐seven renal units of 23 patients with acute RI were identified. The mean age was 59.7 ± 15.7 years. Fourteen patients (60.8%) with RI had atrial fibrillation (AF) as an etiologic factor of which four had concomitant mesenteric ischemia at diagnosis. At presentation, 20 patients (86.9%) had elevated serum lactate dehydrogenase (LDH), 18 patients (78.2%) had leukocytosis, and 16 patients (69.5%) had microscopic hematuria. Two patients with concomitant mesenteric ischemia and AF passed away during follow up. Mean eGFR was 70.8 ± 23.2 mL\u002Fmin\u002F1.73 m\u003Cjats:sup>2\u003C\u002Fjats:sup> at admission and increased to 82.3 ± 23.4 mL\u002Fmin\u002F1.73 m\u003Cjats:sup>2\u003C\u002Fjats:sup> at 1 year follow up. RI should be considered in patients with persistent flank or abdominal pain, particularly if they are at high risk of thromboembolism. Antiplatelet and\u002For anticoagulant drugs are both effective treatment options according to the amplitude of the infarct for preserving kidney functions.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":1577},"Midterm renal functions following acute renal infarction",{"VOID":1579},"10.1016\u002Fj.kjms.2015.07.005","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1607551X15001692",[1582,1597,1612,1624,1636],{"id":1583,"sortIndex":313,"researcher":18,"roles":1584,"affiliations":1585,"properties":1594},"b11d6db9-f3ce-450e-a11e-adeea87c4274",[652],[1586],{"id":18,"sortIndex":19,"affiliation":1587,"properties":18},{"id":1588,"createTime":1589,"updateTime":1589,"relativeEntities":1590,"slug":18,"properties":1591,"entityType":38,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19},"2b4e861b-4892-4142-bf2b-7bfa30236bd2","2023-12-06T12:04:49.834+00:00",[],{"title":1592},{"VI":1593},"Department 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RB, 2001, Cancer: Principles and Practice of Oncology, 1028\nMacciarini P, 2004, Uncommon primary mediastinal tumours, Lancet Oncol, 5, 107, 10.1016\u002FS1470-2045(04)01385-3\n10.1200\u002FJCO.2002.07.062\n10.1002\u002Fcncr.10738\n10.1002\u002Fcncr.11068\n10.1148\u002Frg.242035082\n10.1016\u002F0002-9343(62)90167-5\n10.1002\u002F1097-0142(19900401)65:7\u003C1641::AID-CNCR2820650731>3.0.CO;2-U\n10.1002\u002F(SICI)1097-0142(20000301)88:5\u003C1051::AID-CNCR15>3.0.CO;2-R\n10.1002\u002F1097-0142(20010401)91:7\u003C1394::AID-CNCR1144>3.0.CO;2-Y\n10.1093\u002Fjjco\u002Fhyh062\nPectasides D, 1999, Platinum‐ based chemotherapy of primary extragonadal germ cell tumours: The Hellenic Cooperative Oncology Group experience, Oncology, 57, 1, 10.1159\u002F000011993\n10.1038\u002Fsj.bmt.1704704\n10.1093\u002Fannonc\u002Fmdi017\nMostofi FK, 1977, International Histological Classification of Tumors, 137\nYaui H, 1999, Thoracic and cardiovascular surgery in Japan during 1997. Annual report by the Japanese Association for Thoracic Surgery, Jpn J Thorac Cardiovasc Surg, 47, 236\n10.1016\u002FS0022-5223(19)39090-7\n10.1016\u002FS0022-5223(19)38852-X\n10.1002\u002F1097-0142(19930915)72:6\u003C1894::AID-CNCR2820720617>3.0.CO;2-6\nMoran CA, 1997, Primary germ cell tumours of the mediastinum. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging, Cancer, 15, 681\n10.1378\u002Fchest.99.2.472\n10.1016\u002FS0959-8049(97)10021-1\n10.1002\u002F1097-0142(19940401)73:7\u003C1971::AID-CNCR2820730731>3.0.CO;2-A",{"EN":1691},"\u003Cjats:sec>\u003Cjats:label \u002F>\u003Cjats:p>Primary mediastinal germ‐cell tumors (GCTs) without gonadal involvement are rare and can be divided into benign mature teratoma and malignant seminoma or nonseminoma. We describe our experience of malignant mediastinal GCTs and compare the presentations and outcome with those of benign teratomas. Four malignant GCTs (1 seminoma, 1 choriocarcinoma, and 2 yolk‐sac tumors) have been treated in our hospital. All patients were men with obvious symptoms before diagnosis. The patient with seminoma was treated with surgery and radiation, while those with nonseminoma tumors were treated with chemotherapy and\u002For surgery. Two patients died, one with extended pulmonary metastasis and the other with relapsed disease and high levels of tumor markers. Compared with the nine cases of benign teratomas, the four malignant GCTs showed overwhelming male dominance, advanced symptoms at presentation, and poor outcome. These cases highlight the important role of disease staging and tumor‐marker levels in malignant GCTs, and suggest that new treatment strategies for malignant GCTs await further investigation.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":1693},"Poor Outcomes in Patients with Primary Malignant Mediastinal Germ‐cell 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