[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_f5b73086-61b4-4d2e-b46b-1b8ffe84d1ca":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:f5b73086-61b4-4d2e-b46b-1b8ffe84d1ca,\"}":25},{"code":4,"data":5,"meta":18},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":20,"manageAffiliations":21,"indexDatabases":22,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},"f5b73086-61b4-4d2e-b46b-1b8ffe84d1ca","2025-07-10T16:15:33.506+00:00","2026-03-24T09:00:17.763+00:00",[],"T%E1%BA%A1p-ch%C3%AD-Y-h%E1%BB%8Dc-l%C3%A2m-s%C3%A0ng-B%E1%BB%87nh-vi%E1%BB%87n-Trung-%C6%AF%C6%A1ng-Hu%E1%BA%BF",{"issn":12,"title":14},{"VOID":13},"30304733",{"VOID":15},"Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế","PUBLISHER","PENDING",null,0,[],[],[],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome","JOURNAL",{"meta":26,"data":28},{"total":27},"14",[29,132,201,324,432,535,669,774,845,947],{"id":30,"createTime":31,"updateTime":31,"relativeEntities":32,"slug":33,"properties":34,"entityType":47,"verifyStatus":17,"verifyTime":48,"verifyNote":49,"syncStatus":17,"languages":50,"translateLanguages":18,"viewCount":19,"primaryUrl":52,"fullTextUrl":53,"authors":54,"publicationType":78,"publisherRelationship":79,"citationCount":72,"citationInfo":93,"publishDate":96,"publishYear":94,"citationAnalyzeStatus":97,"lastCitationAnalyze":48,"indexDatabases":18,"openAccess":18,"references":98,"isForceReanalyzing":131},"843810cb-c1fe-4829-9481-cfc5cdd81662","2025-07-11T22:08:37.823+00:00",[],"%E1%BB%A8ng-d%E1%BB%A5ng-c%C3%A1c-v%E1%BA%A1t-da-c%C6%A1-c%C3%B3-cu%E1%BB%91ng-trong-t%E1%BA%A1o-h%C3%ACnh-khuy%E1%BA%BFt-h%E1%BB%95ng-sau-ph%E1%BA%ABu-thu%E1%BA%ADt-tri%E1%BB%87t-c%C4%83n-ung-th%C6%B0-bi%E1%BB%83u-m%C3%B4-khoang-mi%E1%BB%87ng-t%E1%BA%A1i-b%E1%BB%87nh-vi%E1%BB%87n-trung-%C6%B0%C6%A1ng-hu%E1%BA%BF",{"keywords":35,"gsPaper":37,"abstract":39,"title":42,"doi":45},{"VI":36},"Từ khóa: Ung thư khoang miệng; vạt cân cơ thái dương; vạt dưới hàm; vạt cơ ngực lớn.",{"VOID":38},"[\"4702794090413709621\"]",{"VI":40,"EN":41},"Mục tiêu: Đánh giá kết quả ứng dụng các vạt da cơ có cuống trong tạo hình khuyết hổng sau phẫu thuật triệt căn và điều trị ung thư biểu mô khoang miệng tại bệnh viện Trung ương HuếĐối tượng, phương pháp: Nghiên cứu mô tả tiến cứu, có can thiệp lâm sàng trên 34 bệnh nhân ung thư biểu mô vảy khoang miệng được phẫu thuật tại Bệnh viện Trung ương Huế từ tháng 03 năm 2020 đến tháng 12 năm 2022.Kết quả: Đã sử dụng 34 vạt da cơ có cuống trong tạo hình khuyết hổng sau phẫu thuật triệt căn ung thư biểu mô khoang miệng. Trong đó Vạt cân thái dương sử dụng cho 3 trường hợp (8,8%). Vạt cân cơ thái dương sử dụng cho 6 trường hợp (17,6%). Vạt da cân cơ dưới hàm sử dụng cho 15 trường hợp (44,1%). Vạt da cân cơ ngực lớn sử dụng cho 10 trường hợp (29,5%). Kết quả nghiên cứu với 88,2% vạt sống tốt, không có biến chứng nặng sau mổ, phục hồi chức năng tốt và tỷ lệ tái phát thấp sau mổ.Kết luận: Sử dụng các vạt da cơ có cuống linh hoạt là lựa chọn phù hợp cho các tổn khuyết trung bình và lớn sau phẫu thuật cùng với tái tạo cơ quan quan trọng nhằm bảo tồn chức năng sống và hình thái của vùng khoang miệng cho bệnh nhân ung thư.Từ khóa: Ung thư khoang miệng; vạt cân cơ thái dương; vạt dưới hàm; vạt cơ ngực lớn\n ","Objective: To evaluate the results of application of pedicled musculocutaneous flaps in defect reconstruction after surgery of oral cancer at Hue Central Hospital.Methods: A prospective, clinical interventional descriptive study on 34 oral squamous cell carcinoma patients operated at Hue Central Hospital from March 2020 to December 2022.Results: 34 pedicled musculocutaneous flaps were used in defect reconstruction after surgery of oral cancer. Four types of flaps were use, in which the temporalis fascia flap was used for 3 cases (8.8%), the temporalis myofascial flap was used for 6 cases (17.6%), the submandibular fascia flap was used for 15 cases (44.1%) and the pectoralis major myocutaneous one was used for 10 cases (29.5%). The results of the study showed that 88,2% of flaps were good. There were no serious complications after surgery. Good function recovery and low recurrence rate were recorded after surgery.Conclusion: Using flexible pedicled musculocutaneous flaps is a suitable choice for moderate and large defects after surgery along with major organ reconstruction to preserve vital function and morphology of the oral cavity for cancer patients.Keywords: Oral cancer; temporalis myofascial flap; submandibular flaps; pectoralis major myocutaneous flaps",{"VI":43,"EN":44},"Ứng dụng các vạt da cơ có cuống trong tạo hình khuyết hổng sau phẫu thuật triệt căn ung thư biểu mô khoang miệng tại bệnh viện trung ương huế","Application of pedicled musculocutaneous flaps in defect reconstruction after surgery of oral cancer at hue central hospital",{"VOID":46},"10.38103\u002Fjcmhch.85.12","PUBLICATION","2025-07-11T22:08:37.822+00:00","Author affiliation is blank",[51],"VI","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F801","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F801\u002F661",[55,63,70],{"id":56,"sortIndex":57,"researcher":18,"roles":58,"affiliations":59,"properties":60},"939bd81d-17b8-47b4-972e-258624e63b0b",2,[],[],{"title":61},{"EN":62},"Trần Nhật Huy",{"id":64,"sortIndex":19,"researcher":18,"roles":65,"affiliations":66,"properties":67},"285d48d0-c547-4fa9-b892-0fcc0d371848",[],[],{"title":68},{"EN":69},"Nguyễn Hồng Lợi",{"id":71,"sortIndex":72,"researcher":18,"roles":73,"affiliations":74,"properties":75},"dc0fd9b5-4080-4061-8fce-903d47f5c7fb",1,[],[],{"title":76},{"EN":77},"Nguyễn Văn Khánh","ARTICLE",{"url":18,"publisher":80,"properties":88},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":81,"slug":10,"properties":82,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":85,"manageAffiliations":86,"indexDatabases":87,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":83,"title":84},{"VOID":13},{"VOID":15},[],[],[],{"pages":89,"issue":91},{"VOID":90},"80 - 88",{"VOID":92},"85",{"total":72,"publishYear":94,"statisticByYear":95},2023,{},"2023-01-01","DONE_ANALYZE_CITATION",[99,101,103,105,107,109,111,113,115,117,119,121,123,125,127,129],{"id":18,"text":100,"url":18,"identifiers":18},"Pfister DG, Spencer S, Adelstein D, Adkins D, Anzai Y, Brizel DM, et al. Head and Neck Cancers, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2020;18(7):873-898.",{"id":18,"text":102,"url":18,"identifiers":18},"Pham DX, Phung AHT, Nguyen HD, Bui TD, Mai LD, Tran BNH, et al. Trends in colorectal cancer incidence in Ho Chi Minh City, Vietnam (1996-2015): Joinpoint regression and age-period-cohort analyses. Cancer Epidemiol. 2022;77102113.",{"id":18,"text":104,"url":18,"identifiers":18},"Pham T, Bui L, Kim G, Hoang D, Tran T, Hoang M. Cancers in Vietnam-Burden and Control Efforts: A Narrative Scoping Review. Cancer Control. 2019;26(1):1073274819863802.",{"id":18,"text":106,"url":18,"identifiers":18},"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics",{"id":18,"text":108,"url":18,"identifiers":18},": GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209-249.",{"id":18,"text":110,"url":18,"identifiers":18},"Brown JS, Rogers SN, McNally DN, Boyle M. A modified classification for the maxillectomy defect. Head Neck. 2000;22(1):17-26.",{"id":18,"text":112,"url":18,"identifiers":18},"Parmar PS , Goldstein DP. The submental island flap in head and neck reconstruction. Curr Opin Otolaryngol Head Neck Surg. 2009;17(4):263-6.",{"id":18,"text":114,"url":18,"identifiers":18},"Jaquet Y, Higgins KM, Enepekides DJ. The temporoparietal fascia flap: a versatile tool in head and neck reconstruction. Curr Opin Otolaryngol Head Neck Surg. 2011;19(4):235-41.",{"id":18,"text":116,"url":18,"identifiers":18},"Tan O, Atik B, Parmaksizoglu D. Soft-tissue augmentation of the middle and lower face using the deepithelialized submental flap. Plast Reconstr Surg. 2007;119(3):873-9.",{"id":18,"text":118,"url":18,"identifiers":18},"Chen WL, Li JS, Yang ZH, Huang ZQ, Wang JU, Zhang B. Two submental island flaps for reconstructing oral and maxillofacial defects following cancer ablation. J Oral Maxillofac Surg. 2008;66(6):1145-56.",{"id":18,"text":120,"url":18,"identifiers":18},"Patel UA, Bayles SW, Hayden RE. The submental flap: A modified technique for resident training. Laryngoscope. 2007;117(1):186-9.",{"id":18,"text":122,"url":18,"identifiers":18},"Milenović A, Virag M, Uglesić V, Aljinović-Ratković N. The pectoralis major flap in head and neck reconstruction: first 500 patients. J Craniomaxillofac Surg. 2006;34(6):340-3.",{"id":18,"text":124,"url":18,"identifiers":18},"Liu M, Liu W, Yang X, Guo H, Peng H. Pectoralis Major Myocutaneous Flap for Head and Neck Defects in the Era of Free Flaps: Harvesting Technique and Indications. Sci Rep. 2017;746256.",{"id":18,"text":126,"url":18,"identifiers":18},"Sơn LV, Phục hồi các tổn khuyết vùng hàm mặt bằng vạt cân- cơ thái dương. 2004, Đại học Y Hà Nội.",{"id":18,"text":128,"url":18,"identifiers":18},"Vermorken JB , Specenier P. Optimal treatment for recurrent\u002Fmetastatic head and neck cancer. Ann Oncol.",{"id":18,"text":130,"url":18,"identifiers":18},";21 Suppl 7vii252-61.",false,{"id":133,"createTime":134,"updateTime":135,"relativeEntities":136,"slug":137,"properties":138,"entityType":47,"verifyStatus":17,"verifyTime":18,"verifyNote":146,"syncStatus":17,"languages":147,"translateLanguages":18,"viewCount":19,"primaryUrl":149,"fullTextUrl":150,"authors":151,"publicationType":78,"publisherRelationship":181,"citationCount":19,"citationInfo":195,"publishDate":198,"publishYear":196,"citationAnalyzeStatus":97,"lastCitationAnalyze":134,"indexDatabases":18,"openAccess":18,"references":199,"isForceReanalyzing":131},"2b32f896-3589-4391-b358-1b6acfff7f09","2025-07-13T16:26:30.098+00:00","2025-07-13T20:13:10.242+00:00",[],"Analysis-of-relapse-childhood-acute-lymphoblastic-leukemia-at-Hue-Cenntral-Hospital-in-Vietnam",{"keywords":139,"gsPaper":140,"abstract":142,"title":144},{},{"VOID":141},"15994929821384192496",{"EN":143},".",{"EN":145},"Analysis of relapse childhood acute lymphoblastic leukemia at Hue Cenntral Hospital in Vietnam","Created by PDF Paper Link 2569735",[148],"EN","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F1056","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F1056\u002F883",[152,160,167,174],{"id":153,"sortIndex":154,"researcher":18,"roles":155,"affiliations":156,"properties":157},"a3ed1f14-46fa-4256-a36d-11f17c703c62",3,[],[],{"title":158},{"EN":159},"Kazuyo Watanabe",{"id":161,"sortIndex":72,"researcher":18,"roles":162,"affiliations":163,"properties":164},"dd6ff4c2-2c72-4376-9e8b-61a8604841d6",[],[],{"title":165},{"EN":166},"Tran Kiem Hao",{"id":168,"sortIndex":19,"researcher":18,"roles":169,"affiliations":170,"properties":171},"4e916e1c-ec30-40b7-9863-17eae2820b3b",[],[],{"title":172},{"EN":173},"Nguyen Thi Kim Hoa",{"id":175,"sortIndex":57,"researcher":18,"roles":176,"affiliations":177,"properties":178},"3c3f862b-58bd-445e-ac49-bb64e2101e4c",[],[],{"title":179},{"EN":180},"Chau Van Ha",{"url":18,"publisher":182,"properties":190},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":183,"slug":10,"properties":184,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":187,"manageAffiliations":188,"indexDatabases":189,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":185,"title":186},{"VOID":13},{"VOID":15},[],[],[],{"pages":191,"issue":193},{"VOID":192},"19-24",{"VOID":194},"51",{"total":19,"publishYear":196,"statisticByYear":197},2018,{},"2018-01-01",[200],{"id":18,"text":143,"url":18,"identifiers":18},{"id":202,"createTime":203,"updateTime":203,"relativeEntities":204,"slug":205,"properties":206,"entityType":47,"verifyStatus":17,"verifyTime":214,"verifyNote":49,"syncStatus":17,"languages":215,"translateLanguages":18,"viewCount":19,"primaryUrl":216,"fullTextUrl":217,"authors":218,"publicationType":78,"publisherRelationship":275,"citationCount":19,"citationInfo":289,"publishDate":292,"publishYear":290,"citationAnalyzeStatus":97,"lastCitationAnalyze":214,"indexDatabases":18,"openAccess":18,"references":293,"isForceReanalyzing":131},"0093c211-86eb-4080-827a-cdbdd6e2240b","2025-07-13T20:03:48.771+00:00",[],"Evaluating-the-effectiveness-of-ketamine-plus-atropin-as-anesthesia-for-intrathecal-chemotherapy-and-bone-marrow-procedure-at-Hue-central-hospital-Vietnam",{"keywords":207,"gsPaper":208,"abstract":210,"title":212},{},{"VOID":209},"[\"13305629006173054573\"]",{"EN":211},"ABSTRACTBackground: Ketamine is a phencyclidine and cyclohexamine derivative. Ketamine and atropine have been increasingly used in recent years as an effective form of deep sedation\u002Fanaesthesia in children in developed countries, but not in developing countries like Vietnam. Objective: This pioneer trial aimed to evaluate the effectiveness of using ketamine plus atropine as anaesthetic agents for paediatric oncology procedures. From this study, we establish a protocol for anaesthesia in paediatric oncology procedures. Methods: A descriptive and prospective study on 223 paediatric patients of both sexes (129 males and 94 females) aged 7.2 months to 15 years (mean age: 4.0 ± 3.4 years) and with body weight between 6.5 to 55 kg (mean weight: 15.3 ± 6.2 kg) was carried out from January 2015 to June 2019. The patients had been diagnosed with acute leukaemia, lymphoma or solid tumor. They underwent intrathecal chemotherapy and bone marrow aspirations or bone marrow biopsy for diagnostic as well as therapeutic purposes. After obtaining informed consent from their parents, the research was performed. Datas were analysed by Medcalc software.Results: The total number of procedures was 810. Bone marrow aspiration was performed 402 times, bone marrow biopsy was done 30 times and intrathecal chemotherapy given 378 times. All procedures were successfully completed. The mean dose of ketamine and atropine used 1.55 ± 0.31 mg\u002Fkg and 0.100 ± 0.029 mg respectively. The recovery time was 9.2 ± 7.3 minutes. Only 0.12% experienced apnoea; 1.2% muscular hypertonicity; 4.3% nystagmus, and hyperactivity; 3.7% hypersalivation, 2.5% hallucination and 5.5% vomiting; none of the patients had laryngospasm or transient rash. All of the patients’ parents were satisfied with the use of anaesthetics. Conclusions: This is a pioneer trial for children in Vietnam. The dose of 1.5 mg\u002Fkg intravenous ketamine and 0.1mg atropine were found to be effective and suitable dose in children requiring deep sedation for painful procedures and produce only minimal side effects. We established a protocol with the above doses and continue to apply this in order to reduce pain, trauma, and complications during the procedures.",{"EN":213},"Evaluating the effectiveness of ketamine plus atropin as anesthesia for intrathecal chemotherapy and bone marrow procedure at Hue central hospital, Vietnam","2025-07-13T20:03:48.770+00:00",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F671","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F671\u002F557",[219,226,232,239,245,251,259,267],{"id":220,"sortIndex":221,"researcher":18,"roles":222,"affiliations":223,"properties":224},"e203667c-90d3-48cd-97ee-c176a02e2dd2",6,[],[],{"title":225},{"EN":159},{"id":227,"sortIndex":154,"researcher":18,"roles":228,"affiliations":229,"properties":230},"caa30305-521f-4dda-b44f-417794150e21",[],[],{"title":231},{"EN":180},{"id":233,"sortIndex":19,"researcher":18,"roles":234,"affiliations":235,"properties":236},"f5e6cdb2-9c3f-4d8c-9151-ebe4925297ab",[],[],{"title":237},{"EN":238},"Pham Nhu Hiep",{"id":240,"sortIndex":72,"researcher":18,"roles":241,"affiliations":242,"properties":243},"0a3f1d26-4f2e-4769-b93d-979df58c5532",[],[],{"title":244},{"EN":166},{"id":246,"sortIndex":57,"researcher":18,"roles":247,"affiliations":248,"properties":249},"57346e54-7474-4c95-8c89-f250d2af4abd",[],[],{"title":250},{"EN":173},{"id":252,"sortIndex":253,"researcher":18,"roles":254,"affiliations":255,"properties":256},"25c06721-5b51-4e26-b135-79fa5eba2083",4,[],[],{"title":257},{"EN":258},"Phan Canh Duy",{"id":260,"sortIndex":261,"researcher":18,"roles":262,"affiliations":263,"properties":264},"0b3b720e-0f25-41cc-b6d8-f3a0a87e5086",7,[],[],{"title":265},{"EN":266},"Bui Ngoc  Lan",{"id":268,"sortIndex":269,"researcher":18,"roles":270,"affiliations":271,"properties":272},"003a4643-f503-466b-b1bb-7f283ca6f7a9",5,[],[],{"title":273},{"EN":274},"Nguyen Huu Son",{"url":18,"publisher":276,"properties":284},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":277,"slug":10,"properties":278,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":281,"manageAffiliations":282,"indexDatabases":283,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":279,"title":280},{"VOID":13},{"VOID":15},[],[],[],{"pages":285,"issue":287},{"VOID":286},"3-7",{"VOID":288},"56",{"total":19,"publishYear":290,"statisticByYear":291},2019,{},"2019-01-01",[294,296,298,300,302,304,306,308,310,312,314,316,318,320,322],{"id":18,"text":295,"url":18,"identifiers":18},"Kidd, L.R., Lyons, S.C., and Lloyd, G. (2016) Paediatric procedural sedation using ketamine in a UK emergency department: a 7 year review",{"id":18,"text":297,"url":18,"identifiers":18},"of practice. Br J Anaesth, 116, 518-23.",{"id":18,"text":299,"url":18,"identifiers":18},"Ng, K.C. Ang, S.Y. (2002) Sedation with ketamine for paediatric procedures in the emergency department-a review of 500 cases. Singapore Med J, 43, 300-4.",{"id":18,"text":301,"url":18,"identifiers":18},"Heinz, P., Geelhoed, G.C., Wee, C., and Pascoe, E.M. (2006) Is atropine needed with ketamine sedation? A prospective, randomised, double",{"id":18,"text":303,"url":18,"identifiers":18},"blind study. Emerg Med J, 23, 206-9.",{"id":18,"text":305,"url":18,"identifiers":18},"Traivaree, C., Jindakam, W., Monsereenusorn, C., Rujkijyanont, P., and Lumkul, R. (2014) The factors of ketamine that affect sedation in children with oncology procedures: parent satisfaction perspective. J Med Assoc Thai, 97 Suppl 2, S19-24.",{"id":18,"text":307,"url":18,"identifiers":18},"Heilbrunn, B.R., Chang, T.P., and Liu, D.R. (2015) A retrospective comparison of ketamine dosing regimens for pediatric procedural sedation. Eur J Emerg Med, 22, 111-6.",{"id":18,"text":309,"url":18,"identifiers":18},"Evans, D., Turnham, L., Barbour, K., Kobe, J., Wilson, L., Vandebeek, C. (2005) Intravenous ketamine sedation for painful oncology procedures. Paediatr Anaesth, 15, 131-8.",{"id":18,"text":311,"url":18,"identifiers":18},"Mason, K.P., Padua, H., Fontaine, P.J., and Zurakowski, D. (2009) Radiologist-supervised ketamine sedation for solid organ biopsies in children and adolescents. AJR Am J Roentgenol, 192, 1261-5.",{"id":18,"text":313,"url":18,"identifiers":18},"Kye, Y.C., Rhee, J.E., Kim, K., Kim, T., Jo, Y.H., Jeong, J.H. (2012) Clinical effects of adjunctive atropine during ketamine sedation in pediatric emergency patients. Am J Emerg Med, 30, 1981-5.",{"id":18,"text":315,"url":18,"identifiers":18},"Slonim, A.D. Ognibene, F.P. (1998) Sedation for pediatric procedures, using ketamine and midazolam, in a primarily adult intensive care unit: a retrospective evaluation. Crit Care Med, 26, 1900-4.",{"id":18,"text":317,"url":18,"identifiers":18},"Brown, L., Christian-Kopp, S., Sherwin, T.S., Khan, A., Barcega, B., Denmark, T.K. (2008) Adjunctive atropine is unnecessary during",{"id":18,"text":319,"url":18,"identifiers":18},"ketamine sedation in children. Acad Emerg Med, 15, 314-8.",{"id":18,"text":321,"url":18,"identifiers":18},"Patterson, A.C., Wadia, S.A., Lorenz, D.J., and Stevenson, M.D. (2017) Changes in blood pressure and heart rate during sedation with ketamine in the pediatric ED. Am J Emerg Med, 35, 322-325.",{"id":18,"text":323,"url":18,"identifiers":18},"Shi, J., Li, A., Wei, Z., Liu, Y., Xing, C., Shi, H. (2018) Ketamine versus ketamine pluses atropine for pediatric sedation: A meta-analysis. Am J Emerg Med, 36, 1280-1286.",{"id":325,"createTime":326,"updateTime":326,"relativeEntities":327,"slug":328,"properties":329,"entityType":47,"verifyStatus":17,"verifyTime":326,"verifyNote":49,"syncStatus":17,"languages":339,"translateLanguages":18,"viewCount":19,"primaryUrl":340,"fullTextUrl":341,"authors":342,"publicationType":78,"publisherRelationship":389,"citationCount":19,"citationInfo":403,"publishDate":406,"publishYear":404,"citationAnalyzeStatus":97,"lastCitationAnalyze":326,"indexDatabases":18,"openAccess":18,"references":407,"isForceReanalyzing":131},"cc5ef0c2-f6e7-45b0-8bbb-9a7c8ba02f15","2025-07-13T19:52:42.779+00:00",[],"Ganglioneuroma-of-mediastinum-and-adrenal-glanda-case-report",{"keywords":330,"gsPaper":331,"abstract":333,"title":335,"doi":337},{},{"VOID":332},"[\"14276970087794383936\"]",{"EN":334},"Introduction: Ganglioneuroma is a rare benign nervous tumor arising from sympathetic ganglion which commonly occurs at posterior mediastinum, retroperitoneum and adrenal gland.Case: We report a 6 year-old boy who presented with abdomial pain. Compute tomography scan and magnetic resonance imaging (MRI) showed one tumor at his right posterior mediastinum area measuring 8.3x6.3x5.3cm, and the other tumor at his right adrenal gland measuring 3.9x3.4x3.2 cm. A biopsy showed ganglioneuroma, and complete resection of both tumors. Post operation biopsy confirm definitive diagnosis as ganglioneuroma. The patient is healthy from surgery.Conclusion: Ganglioneuroma is benign. The treatment is complete surgical resection. Prognosis after surgical resection seems to be so good, without any recurrences or need for adjuvant therapy.",{"EN":336},"Ganglioneuroma of mediastinum and adrenal glanda case report",{"VOID":338},"10.38103\u002Fjcmhch.2020.64.13",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F2122","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F2122\u002F1849",[343,349,356,363,369,375,382],{"id":344,"sortIndex":19,"researcher":18,"roles":345,"affiliations":346,"properties":347},"bded5590-a476-4a58-8181-b5a9c16373dc",[],[],{"title":348},{"EN":173},{"id":350,"sortIndex":269,"researcher":18,"roles":351,"affiliations":352,"properties":353},"d9424645-eaf3-4c0f-af4b-92f22783b5c5",[],[],{"title":354},{"EN":355},"Pham Nguyen Cuong",{"id":357,"sortIndex":154,"researcher":18,"roles":358,"affiliations":359,"properties":360},"90c98322-0e73-46ca-b336-afdbdb822d69",[],[],{"title":361},{"EN":362},"Phan Anh Vu",{"id":364,"sortIndex":253,"researcher":18,"roles":365,"affiliations":366,"properties":367},"702e4a7c-006b-456d-84aa-2fff1bbf00ea",[],[],{"title":368},{"EN":258},{"id":370,"sortIndex":57,"researcher":18,"roles":371,"affiliations":372,"properties":373},"0593146d-442f-4957-ab82-314f0f730e6b",[],[],{"title":374},{"EN":166},{"id":376,"sortIndex":72,"researcher":18,"roles":377,"affiliations":378,"properties":379},"1cb3a491-c95a-4f56-84cf-5920c5df20d7",[],[],{"title":380},{"EN":381},"Bui Binh Bao Son",{"id":383,"sortIndex":221,"researcher":18,"roles":384,"affiliations":385,"properties":386},"9f598ff5-4fb4-4dec-84e7-4ccbb59aa386",[],[],{"title":387},{"EN":388},"Carlos Rodriguez-Galindo",{"url":18,"publisher":390,"properties":398},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":391,"slug":10,"properties":392,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":395,"manageAffiliations":396,"indexDatabases":397,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":393,"title":394},{"VOID":13},{"VOID":15},[],[],[],{"pages":399,"issue":401},{"VOID":400},"87-91",{"VOID":402},"64",{"total":19,"publishYear":404,"statisticByYear":405},2020,{},"2020-01-01",[408,410,412,414,416,418,420,422,424,426,428,430],{"id":18,"text":409,"url":18,"identifiers":18},"Sawaryn T. [Ganglioneuroma of the mediastinum]. Pol Tyg Lek (Wars) 1959;14:867-70",{"id":18,"text":411,"url":18,"identifiers":18},"Hayat J, Ahmed R, Alizai S, Awan MU. Giant ganglioneuroma of the posterior mediastinum. Interact Cardiovasc Thorac Surg 2011;13:344-5",{"id":18,"text":413,"url":18,"identifiers":18},"Kiflu W, Negussie T. Ganglioneuroma of the Neck: A case report. Ethiop Med J 2017;55:69-71",{"id":18,"text":415,"url":18,"identifiers":18},"Geoerger B, Hero B, Harms D, Grebe J, Scheidhauer K, Berthold F. Metabolic activity and clinical features of primary ganglioneuromas. Cancer 2001;91:1905-13",{"id":18,"text":417,"url":18,"identifiers":18},"Lin PC, Lin SH, Chou SH, Chen YW, Chang TT, Wu JR, et al. Ganglioneuroma of posterior mediastinum in a 6-year-old girl: imaging for pediatric intrathoracic incidentaloma. Kaohsiung J Med Sci 2010;26:496-501",{"id":18,"text":419,"url":18,"identifiers":18},"Sucandy I, Akmal YM, Sheldon DG. Ganglioneuroma of the adrenal gland and retroperitoneum: A case report. N Am J Med Sci 2011;3:336-8",{"id":18,"text":421,"url":18,"identifiers":18},"Mylonas KS, Schizas D, Economopoulos KP. Adrenal ganglioneuroma: What you need to know. World J Clin Cases 2017;5:373-377",{"id":18,"text":423,"url":18,"identifiers":18},"Yorita K, Yonei A, Ayabe T, Nakada H, Nakashima K, Fukushima T, et al. Posterior mediastinal ganglioneuroma with peripheral replacement by white and brown adipocytes resulting in diagnostic fallacy from a false-positive 18F-2-fluoro-2-deoxyglucose-positron emission tomography finding: a case report. J Med Case Rep 2014;8:345",{"id":18,"text":425,"url":18,"identifiers":18},"Chang CY, Hsieh YL, Hung GY, Pan CC, Hwang B. Ganglioneuroma presenting as an asymptomatic huge posterior mediastinal and retroperitoneal tumor. J Chin Med Assoc 2003;66:370-4",{"id":18,"text":427,"url":18,"identifiers":18},"Radin R, David CL, Goldfarb H, Francis IR. Adrenal and extra-adrenal retroperitoneal ganglioneuroma: imaging findings in 13 adults. Radiology 1997;202:703-7",{"id":18,"text":429,"url":18,"identifiers":18},"Guan YB, Zhang WD, Zeng QS, Chen GQ, He JX. CT and MRI findings of thoracic ganglioneuroma. Br J Radiol 2012;85:e365-72",{"id":18,"text":431,"url":18,"identifiers":18},"Kizildag B, Alar T, Karatag O, Kosar S, Akman T, Cosar M. A case of posterior mediastinal ganglioneuroma: the importance of preoperative multiplanar radiological imaging. Balkan Med J 2013;30:126-8",{"id":433,"createTime":434,"updateTime":434,"relativeEntities":435,"slug":436,"properties":437,"entityType":47,"verifyStatus":17,"verifyTime":447,"verifyNote":49,"syncStatus":17,"languages":448,"translateLanguages":18,"viewCount":19,"primaryUrl":449,"fullTextUrl":450,"authors":451,"publicationType":78,"publisherRelationship":497,"citationCount":19,"citationInfo":510,"publishDate":406,"publishYear":404,"citationAnalyzeStatus":97,"lastCitationAnalyze":447,"indexDatabases":18,"openAccess":18,"references":512,"isForceReanalyzing":131},"9ef031fe-7c10-4cc7-bb07-4e29061c6393","2025-07-13T19:49:49.851+00:00",[],"-Study-on-clinical-laboratory-features-and-the-result-of-minimal-residual-disease-after-induction-phase-in-childhood-acute-lymphoblastic-leukemia-at-Hue-Central-Hospital-in-Vietnam",{"keywords":438,"gsPaper":439,"abstract":441,"title":443,"doi":445},{},{"VOID":440},"[\"15927677226743405960\"]",{"EN":442},"Background: Acute lymphoblastic leukemia (ALL) is the most common malignant disease in children. Mininal residual disease (MRD) levels after induction phase predict outcome and may select patients for therapy intensification.Objective: To analyse clinical presentations, laboratory features, especially the result of minimal levels in childhood acute lymphoblastic leukemia patientsMethods: It was a prospective study on chilhood acute lymphoblastic leukemia patients who admitted hospital since April, 2018 to May, 2020.Results: There were 38 new patients, in which, 68.4% patients with standard risk, and 31.6% patients with high risk; the ratio of male to female was 2.16:1. The median age was 4.0 years (range: 0.66 to 15). The percentage of B-ALL, T-ALL and combined B and T- ALL were 81.6%, 15.8% and 2.6% respectively. The most common symptoms were anemia (86.8%), fever (76.3%), hepatomegaly (68.4%), splenomegaly (60.5%), enlarged lymph nodes (55.3%). For laboratory features, 26.4% patients had white blood cell (WBC) ≥ 50x109\u002Fl, 76.3% patients had platelet (PLT) < 100x109\u002Fl, 84.6% patients had blood hemoglobin level (Hb) < 10 g\u002Fdl. Lactate dehydrogenase (LDH) and C- reative protein (CRP) increased in most of patients, accounted for 89.5% and 73.7% respectively. After induction, complete remission which based on less than 5% blasts achieved 97.4%. However, MRD after induction phase with threshold ≤ 0.01% accounted for 78.9%. And based on MRD, we adjusted intensive chemotherapy for 4 patients.Conclusion: The most common clinical presentation was anemia, fever, hepatosplenomegaly, bone pain, bleeding. The result of MRD levels is more sensitive and precise to evaluate the responde after induction phase. Therefore, we could adjust intensitive therapy for some patients with high MRD levels to improve the treatment outcome.",{"EN":444}," Study on clinical, laboratory features and the result of minimal residual disease after induction phase in childhood acute lymphoblastic leukemia at Hue Central Hospital in Vietnam",{"VOID":446},"10.38103\u002Fjcmhch.2020.64.3","2025-07-13T19:49:49.850+00:00",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F2120","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F2120\u002F1847",[452,459,465,472,479,485,491],{"id":453,"sortIndex":269,"researcher":18,"roles":454,"affiliations":455,"properties":456},"d1616bcc-f390-4f53-8410-420761007bae",[],[],{"title":457},{"EN":458},"Phan Thi Thuy Hoa",{"id":460,"sortIndex":57,"researcher":18,"roles":461,"affiliations":462,"properties":463},"d16fee15-c8b2-4916-8a39-49486077aa71",[],[],{"title":464},{"EN":166},{"id":466,"sortIndex":72,"researcher":18,"roles":467,"affiliations":468,"properties":469},"9759ba4d-8624-415a-9c59-5db86914ffe8",[],[],{"title":470},{"EN":471},"Phan Hung Viet",{"id":473,"sortIndex":253,"researcher":18,"roles":474,"affiliations":475,"properties":476},"29747bd1-6a1a-42d9-b924-017ed347ec4d",[],[],{"title":477},{"EN":478},"Bui Thi Thu Thanh",{"id":480,"sortIndex":19,"researcher":18,"roles":481,"affiliations":482,"properties":483},"35f1b3bf-e636-4abc-b1fc-b37446da5f05",[],[],{"title":484},{"EN":173},{"id":486,"sortIndex":154,"researcher":18,"roles":487,"affiliations":488,"properties":489},"7052e82e-89f5-44b8-aa67-00fb2ae3b9c6",[],[],{"title":490},{"EN":381},{"id":492,"sortIndex":221,"researcher":18,"roles":493,"affiliations":494,"properties":495},"ddeae8c7-13e2-4197-890f-295139f50212",[],[],{"title":496},{"EN":180},{"url":18,"publisher":498,"properties":506},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":499,"slug":10,"properties":500,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":503,"manageAffiliations":504,"indexDatabases":505,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":501,"title":502},{"VOID":13},{"VOID":15},[],[],[],{"pages":507,"issue":509},{"VOID":508},"26-32",{"VOID":402},{"total":19,"publishYear":404,"statisticByYear":511},{},[513,515,517,519,521,523,525,527,529,531,533],{"id":18,"text":514,"url":18,"identifiers":18},"Fadoo Z, Nisar I, Yousuf F, Lakhani LS, Ashraf S, Imam U, et al. Clinical features and induction outcome of childhood acute lymphoblastic leukemia in a lower\u002Fmiddle income population: A multi-institutional report from Pakistan. Pediatr Blood Cancer 2015;62:1700-8",{"id":18,"text":516,"url":18,"identifiers":18},"Uckun FM, Gaynon PS, Sensel MG, Nachman J, Trigg ME, Steinherz PG, et al. Clinical features and treatment outcome of childhood T-lineage acute lymphoblastic leukemia according to the apparent maturational stage of T-lineage leukemic blasts: a Children’s Cancer Group study. J Clin Oncol 1997;15:2214-21",{"id":18,"text":518,"url":18,"identifiers":18},"Gaynon PS, Desai AA, Bostrom BC, Hutchinson RJ, Lange BJ, Nachman JB, et al. Early response to therapy and outcome in childhood acute lymphoblastic leukemia: a review. Cancer 1997;80:1717-26",{"id":18,"text":520,"url":18,"identifiers":18},"Ravindranath Y. Biology of childhood acute lymphoblastic leukemia (ALL) in low\u002Fmiddle-income countries--A case for using age at diagnosis for defining low-risk all. Pediatr Blood Cancer 2015;62:1687-8",{"id":18,"text":522,"url":18,"identifiers":18},"Howard SC, Pedrosa M, Lins M, Pedrosa A, Pui CH, Ribeiro RC, et al. Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004;291:2471-5",{"id":18,"text":524,"url":18,"identifiers":18},"Al-Sudairy R, Al-Nasser A, Alsultan A, Al Ahmari A, Abosoudah I, Al-Hayek R, et al. Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia in Saudi Arabia: a multi-institutional retrospective national collaborative study. Pediatr Blood Cancer 2014;61:74-80",{"id":18,"text":526,"url":18,"identifiers":18},"Yasmeen N, Ashraf S. Childhood acute lymphoblastic leukaemia; epidemiology and clinicopathological features. J Pak Med Assoc 2009;59:150-3",{"id":18,"text":528,"url":18,"identifiers":18},"Greaves MF, Colman SM, Beard ME, Bradstock K, Cabrera ME, Chen PM, et al. Geographical distribution of acute lymphoblastic leukaemia subtypes: second report of the collaborative group study. Leukemia 1993;7:27-34",{"id":18,"text":530,"url":18,"identifiers":18},"Campana D, Pui CH. Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance. Blood 1995;85:1416-34",{"id":18,"text":532,"url":18,"identifiers":18},"Vora A, Goulden N, Mitchell C, Hancock J, Hough R, Rowntree C, et al. Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. Lancet Oncol 2014;15:809-18",{"id":18,"text":534,"url":18,"identifiers":18},"Yeoh AE, Ariffin H, Chai EL, Kwok CS, Chan YH, Ponnudurai K, et al. Minimal residual disease-guided treatment deintensification for children with acute lymphoblastic leukemia: results from the Malaysia-Singapore acute lymphoblastic leukemia 2003 study. J Clin Oncol 2012;30:2384-92",{"id":536,"createTime":537,"updateTime":537,"relativeEntities":538,"slug":539,"properties":540,"entityType":47,"verifyStatus":17,"verifyTime":548,"verifyNote":49,"syncStatus":17,"languages":549,"translateLanguages":18,"viewCount":19,"primaryUrl":550,"fullTextUrl":551,"authors":552,"publicationType":78,"publisherRelationship":605,"citationCount":19,"citationInfo":618,"publishDate":292,"publishYear":290,"citationAnalyzeStatus":97,"lastCitationAnalyze":548,"indexDatabases":18,"openAccess":18,"references":620,"isForceReanalyzing":131},"9c02af12-5a79-4799-85af-8176389d7428","2025-07-13T16:17:43.194+00:00",[],"Long-term-outcome-of-childhood-acute-myeloid-leukemia-at-Hue-central-hospital",{"keywords":541,"gsPaper":542,"abstract":544,"title":546},{},{"VOID":543},"[\"229575091648168796\"]",{"EN":545},"ABSTRACTBackground: Hue Central Hospital (HCH) plays a key role intreating Acute Myeloid Leukemia (AML) in the central zone of Vietnam which covers geographically vast areas. Before 2010, all the AML patients died, and abandonment rate was more than 50%. The aims of this study are to determine the outcome of newly diagnosed children with AML treated at HCH from 2010 to 2018.Methods: This is a retrospective review of 98 children with AML admitted from January 2010 to December 2018. The diagnosis was confirmed by morphological FAB criteria, cytochemistry and immunophenotype. Patients were treated with using modified AML 7-3 Regimen. Social supports were provided to patients\u002Ffamilies.Results: A total of 98 children with AML were analyzed with median age of 5,6 years ranging from 3 months to 15 years. The male to female ratio was 1,8:1. The overall complete remission (CR) rate on day 21 of induction were 62.2%. 46 patients (46.9%) appeared relapse, in which 27 patients had relapse during the time they recured chemotherapy, 19.4% after finishing chemotherapy. Overall survival (OS) at 8 years were 23.2%. The event-free survival (EFS) at 8 years were 20.2%. Abandonment cases were 4 (4.1%).Conclusion: With less toxic modified protocol, survival rate has been improved and treatment related mortality was minimized though high relapse rate is still an issue. Abandonment has been reduced successfully with holistic strategies such as financial support, managing family group, providing education, early follow-up of patients who missed appointments and free accommodation near hospital for patients\u002Ffamilies.",{"EN":547},"Long-term outcome of childhood acute myeloid leukemia at Hue central hospital","2025-07-13T16:17:43.193+00:00",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F708","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F708\u002F589",[553,559,566,573,579,586,592,598],{"id":554,"sortIndex":253,"researcher":18,"roles":555,"affiliations":556,"properties":557},"22fc543e-349f-4f1d-9258-be729fceaf85",[],[],{"title":558},{"EN":173},{"id":560,"sortIndex":221,"researcher":18,"roles":561,"affiliations":562,"properties":563},"16eecba1-a24e-4093-990a-0d4e264337bf",[],[],{"title":564},{"EN":565},"Truong Thi Kim Yen",{"id":567,"sortIndex":261,"researcher":18,"roles":568,"affiliations":569,"properties":570},"a6ab1c21-c2e3-4638-ba6d-a54809e31c61",[],[],{"title":571},{"EN":572},"Watanabe Kazuyo",{"id":574,"sortIndex":269,"researcher":18,"roles":575,"affiliations":576,"properties":577},"4ae70b35-c566-4b5c-bd22-f18a0aabc446",[],[],{"title":578},{"EN":274},{"id":580,"sortIndex":154,"researcher":18,"roles":581,"affiliations":582,"properties":583},"cb297292-69ec-4ee2-ad08-18343dfb42cc",[],[],{"title":584},{"EN":585},"Phan Huy Thuan",{"id":587,"sortIndex":72,"researcher":18,"roles":588,"affiliations":589,"properties":590},"759ffa9d-0ae1-4499-bb64-61d252c75007",[],[],{"title":591},{"EN":166},{"id":593,"sortIndex":19,"researcher":18,"roles":594,"affiliations":595,"properties":596},"645307f2-1e09-4cbb-a051-6935cb7972ff",[],[],{"title":597},{"EN":180},{"id":599,"sortIndex":57,"researcher":18,"roles":600,"affiliations":601,"properties":602},"48078e1b-70a5-4b6a-b567-579fa7b42bdb",[],[],{"title":603},{"EN":604},"Phan Xuan Mai",{"url":18,"publisher":606,"properties":614},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":607,"slug":10,"properties":608,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":611,"manageAffiliations":612,"indexDatabases":613,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":609,"title":610},{"VOID":13},{"VOID":15},[],[],[],{"pages":615,"issue":617},{"VOID":616},"46-51",{"VOID":288},{"total":19,"publishYear":290,"statisticByYear":619},{},[621,623,625,627,629,631,633,635,637,639,641,643,645,647,649,651,653,655,657,659,661,663,665,667],{"id":18,"text":622,"url":18,"identifiers":18},"Gamis AS, Alonzo TA, Perentesis JP, Meshinchi S, Committee COGAML (2013) Children’s Oncology Group’s 2013 blueprint for research: acute myeloid leukemia. Pediatr Blood Cancer 60: 964-71.",{"id":18,"text":624,"url":18,"identifiers":18},"Horibe K, Saito AM, Takimoto T, Tsuchida M, Manabe A, el al (2013) Incidence and survival rates of hematological malignancies in Japanese children and adolescents (2006-2010): based on registry data from the Japanese Society of Pediatric Hematology. Int J Hematol 98: 74-88.",{"id":18,"text":626,"url":18,"identifiers":18},"Komur M, Erbey F, Bayram I, Tanyeli A (2010) Incidence and prognostic importance of molecular genetic defects in children with acute",{"id":18,"text":628,"url":18,"identifiers":18},"myeloblastic leukemia. Asian Pac J Cancer Prev 11: 1393-5.",{"id":18,"text":630,"url":18,"identifiers":18},"Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, el al (1998) The importance of diagnostic cytogenetics on outcome in AML:",{"id":18,"text":632,"url":18,"identifiers":18},"analysis of 1.612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children’s Leukaemia Working Parties. Blood 92: 2322-33.",{"id":18,"text":634,"url":18,"identifiers":18},"Ter Bals E, Kaspers GJ (2005) Treatment of childhood acute myeloid leukemia. Expert Rev Anticancer Ther 5: 917-29.",{"id":18,"text":636,"url":18,"identifiers":18},"Ward E, DeSantis C, Robbins A, Kohler B, Jemal A (2014) Childhood and adolescent cancer statistics, 2014. CA Cancer J Clin 64: 83-103.",{"id":18,"text":638,"url":18,"identifiers":18},"Viana MB, Cunha KC, Ramos G, Murao M (2003) [Acute myeloid leukemia in childhood: 15-year experience in a single institution]. J Pediatr (Rio J) 79: 489-96.",{"id":18,"text":640,"url":18,"identifiers":18},"Imamura T, Iwamoto S, Kanai R, Shimada A, Terui K, el al (2012) Outcome in 146 patients with paediatric acute myeloid leukaemia treated according to the AML99 protocol in the period 2003-06 from the Japan Association of Childhood Leukaemia Study. Br J Haematol 159: 204-10.",{"id":18,"text":642,"url":18,"identifiers":18},"Creutzig U, van den Heuvel-Eibrink MM, Gibson B, Dworzak MN, Adachi S, el al (2012) Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel. Blood 120: 3187-205.",{"id":18,"text":644,"url":18,"identifiers":18},"Creutzig U, Zimmermann M, Ritter J, Reinhardt D, Hermann J, el al (2005) Treatment strategies and long-term results in paediatric patients",{"id":18,"text":646,"url":18,"identifiers":18},"treated in four consecutive AML-BFM trials. Leukemia 19: 2030-42.",{"id":18,"text":648,"url":18,"identifiers":18},"Sandahl JD, Kjeldsen E, Abrahamsson J, Ha SY, Heldrup J, el al (2014) Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study. Genes Chromosomes Cancer 53: 667-75.",{"id":18,"text":650,"url":18,"identifiers":18},"Dama E, Pastore G, Mosso ML, Maule MM, Zuccolo L, el al (2006) Time trends and prognostic factors for survival from childhood",{"id":18,"text":652,"url":18,"identifiers":18},"cancer: a report from the Childhood Cancer Registry of Piedmont (Italy). Eur J Pediatr 165: 240-9.",{"id":18,"text":654,"url":18,"identifiers":18},"Xu XJ, Tang YM, Song H, Yang SL, Shi SW, el al (2010) Long-term outcome of childhood acute myeloid leukemia in a developing country:",{"id":18,"text":656,"url":18,"identifiers":18},"experience from a children’s hospital in China. Leuk Lymphoma 51: 2262-9.",{"id":18,"text":658,"url":18,"identifiers":18},"Wiangnon S, Veerakul G, Nuchprayoon I, Seksarn P, Hongeng S, el al (2011) Childhood cancer incidence and survival 2003-2005, Thailand: study from the Thai Pediatric Oncology Group. Asian Pac J Cancer Prev 12: 2215-20.",{"id":18,"text":660,"url":18,"identifiers":18},"Chow EJ, Puumala SE, Mueller BA, Carozza SE, Fox EE, el al (2010) Childhood cancer in relation to parental race and ethnicity: a 5-state",{"id":18,"text":662,"url":18,"identifiers":18},"pooled analysis. Cancer 116: 3045-53.",{"id":18,"text":664,"url":18,"identifiers":18},"Jastaniah W, Al Ghemlas I, Al Daama S, Ballourah W, Bayoumy M, el al (2016) Clinical characteristics and outcome of childhood de novo acute myeloid leukemia in Saudi Arabia: A multicenter SAPHOS leukemia group study. Leuk Res 49: 66-72.",{"id":18,"text":666,"url":18,"identifiers":18},"De Pernillo M, Rivas S, Fuentes L, Antillon F, Barr RD (2014) Measurement of socio-economic status in families of children with cancer in Guatemala. Pediatr Blood Cancer 61: 2071-3.",{"id":18,"text":668,"url":18,"identifiers":18},"Navarrete M, Rossi E, Brivio E, Carrillo JM, Bonilla M, el al (2014) Treatment of childhood acute lymphoblastic leukemia in central America: a lower-middle income countries experience. Pediatr Blood Cancer 61: 803-9.",{"id":670,"createTime":671,"updateTime":671,"relativeEntities":672,"slug":673,"properties":674,"entityType":47,"verifyStatus":17,"verifyTime":684,"verifyNote":49,"syncStatus":17,"languages":685,"translateLanguages":18,"viewCount":19,"primaryUrl":686,"fullTextUrl":687,"authors":688,"publicationType":78,"publisherRelationship":717,"citationCount":19,"citationInfo":731,"publishDate":734,"publishYear":732,"citationAnalyzeStatus":97,"lastCitationAnalyze":684,"indexDatabases":18,"openAccess":18,"references":735,"isForceReanalyzing":131},"a00db6ca-5404-4299-b534-b3320c08cc45","2025-07-10T16:15:33.504+00:00",[],"Effects-of-online-learning-on-mental-health-in-nursing-students-A-systematic-review",{"keywords":675,"gsPaper":676,"abstract":678,"title":680,"doi":682},{},{"VOID":677},"[\"4342101013091349086\"]",{"EN":679},"Aim: This systematic review aims to explore the effect of online learning on mental health among nursing students.\r\nMethod: The systematic review was conducted for relevant articles published in all languages from 2014 to 2024 in four electronic databases (PubMed, CINAHL, Cochrane Library, MEDLINE). The search terms included ‘nursing student’, ‘online learning’, and ‘stress’. Studies that were randomized controlled trials or quasi-experimental studies were included.\r\nResults: A total of 2367 articles were found in 4 databases, and 1 randomized control trial was included as the final result. The study results show that nursing students who received the virtual clinical simulation gained a higher anxiety level compared with those who joined the face - to - face program.\r\nConclusion: Online learning causes more anxiety for nursing students than the face - to - face program. However, more RCT or quasi - experimental studies are needed to confirm this conclusion more convincingly.",{"EN":681},"Effects of online learning on mental health in nursing students: A systematic review",{"VOID":683},"10.38103\u002Fjcmhch.97.9","2025-07-10T16:15:33.503+00:00",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F120","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F120\u002F69",[689,696,703,710],{"id":690,"sortIndex":154,"researcher":18,"roles":691,"affiliations":692,"properties":693},"77a718fb-f9b4-4670-851b-2f30afaa9c81",[],[],{"title":694},{"EN":695},"Raufina Riandhani Mulyoto",{"id":697,"sortIndex":19,"researcher":18,"roles":698,"affiliations":699,"properties":700},"5d8db2d6-23d4-49e1-a53a-e24f9b4e366f",[],[],{"title":701},{"EN":702},"Nguyen Thi Quyen",{"id":704,"sortIndex":57,"researcher":18,"roles":705,"affiliations":706,"properties":707},"86c9653b-5943-443f-a864-83931cfa8737",[],[],{"title":708},{"EN":709},"Liao Tzu-Ting",{"id":711,"sortIndex":72,"researcher":18,"roles":712,"affiliations":713,"properties":714},"22637173-68aa-4b28-80b9-81468bad7528",[],[],{"title":715},{"EN":716},"Lili Sofia",{"url":18,"publisher":718,"properties":726},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":719,"slug":10,"properties":720,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":723,"manageAffiliations":724,"indexDatabases":725,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":721,"title":722},{"VOID":13},{"VOID":15},[],[],[],{"pages":727,"issue":729},{"VOID":728},"60-65",{"VOID":730},"97",{"total":19,"publishYear":732,"statisticByYear":733},2024,{},"2024-12-03",[736,738,740,742,744,746,748,750,752,754,756,758,760,762,764,766,768,770,772],{"id":18,"text":737,"url":18,"identifiers":18},"Dube B. Rural Online Learning in the Context of Covid 19 in South Africa: Evoking an Inclusive Education Approach. Multidisciplinary Journal of Educational Research. 2020;1:135-157.",{"id":18,"text":739,"url":18,"identifiers":18},"Sujit KB, Wotto M, and Bélanger P. E-learning, M-learning and D-learning: Conceptual definition and comparative analysis. Sage Journal. 2018;3(2):19-21",{"id":18,"text":741,"url":18,"identifiers":18},"Mukasa J, Michael O, Beatrice M, Amina AM, Priya B, Lalitha J. Nursing Students’ Perspectives and Readiness to Transition to E-Learning During COVID-19 in the UAE: A Cross-Sectional Study. Dove Press Advances in Medical Education and Practice. 2021;7(3):123-125.",{"id":18,"text":743,"url":18,"identifiers":18},"Pitambar P. Online Education: Benefits, Challenges and Strategies During and After COVID-19 in Higher Education. International Journal of Studies in Education. 2020;12(2):37-39",{"id":18,"text":745,"url":18,"identifiers":18},"UNESCO. Distance learning strategies in response to COVID-19 school closures. COVID-19 Education Response Education Sector Issue Notes. 2020;2(1):1-8.",{"id":18,"text":747,"url":18,"identifiers":18},"Bourbannais FF, Langford S, Giannantoni L. Development of a clinical evaluation tool for baccalaureate nursing students. Nursing Education Practice. 2008;8(1):62-71.",{"id":18,"text":749,"url":18,"identifiers":18},"Oducado E. Online Learning in Nursing Education During the COVID-19 Pandemic: Stress, Satisfaction, and Academic Performance. Journal of Nursing Practice. 2021;17:32-25.",{"id":18,"text":751,"url":18,"identifiers":18},"Sklar DP. COVID-19: lessons from the disaster that can improve health professions education. Academic medicine. 2020;9(2):22-24.",{"id":18,"text":753,"url":18,"identifiers":18},"Sekine M, Watanabe M, Nojiri S, Suzuki T, Nishizaki Y, Tomiki Y, & Okada T. Effects of COVID-19 on Japanese medical students’ knowledge and attitudes toward e-learning in relation to performance on achievement tests. PloS one. 2022;17(3), e0265356.",{"id":18,"text":755,"url":18,"identifiers":18},"Sharma D, Bhaskar S. Addressing the Covid-19 burden on medical education and training: the role of telemedicine and tele-education during and beyond the pandemic. Frontiers in public health. 2020;838:1-4.",{"id":18,"text":757,"url":18,"identifiers":18},"Idris F, Ihsan NZ, Khadizah H, Siti R, Shahid M, Hanif A, Rajan R, Lin N. Academic experiences, physical and mental health impact of COVID-19 pandemic on students and lecturers in health care education. BMC Medical Education. 2021;7(2):1-4.",{"id":18,"text":759,"url":18,"identifiers":18},"Zhang JY, Tao S, Ming X, Zhan-Chun F. Learning Burnout: Evaluating the Role of Social Support in Medical Students. Frontiers in Psychology. 2021;1(2):1-3.",{"id":18,"text":761,"url":18,"identifiers":18},"Hansen-Brown AA, Sullivan S, Jacobson B, Holt B, Donovan S. College students’ belonging and loneliness in the context of remote online classes during the COVID-19 pandemic. Online Learning. 2020:26(4), 323-346.",{"id":18,"text":763,"url":18,"identifiers":18},"Wen L, Robyn G, Mingyu H, Changhao W, Shenjun L, Zheng G. Barriers and facilitators to online medical and nursing education during the COVID-19 pandemic: perspectives from international students from low- and middle-income countries and their teaching staff. Human Resources for Health. 2021;1(2):1-3.",{"id":18,"text":765,"url":18,"identifiers":18},"Cobbett S, Snelgrove-Clarke E. Virtual versus face-to-face clinical simulation in relation to student knowledge, anxiety, and self-confidence in maternal-newborn nursing: A randomized controlled trial. Nurse Education Today. 2016;45:179-184.",{"id":18,"text":767,"url":18,"identifiers":18},"Beverley N, Nicole H. Causes of Student Anxiety during Simulation: What the Literature Says. Clinical Simulation in Nursing. 2013;9(1):e507-e512.",{"id":18,"text":769,"url":18,"identifiers":18},"Ryan C, Terry K. Nursing Students’ Anxiety and Clinical Performance. Journal of Nursing Education. 2011;50(5):286-9.",{"id":18,"text":771,"url":18,"identifiers":18},"Teresa NG, Caralise WH, Francine P, Kimberly HR. The Effects of Simulated Clinical Experiences on Anxiety: Nursing Students’ Perspectives. Clinical Simulation in Nursing. 2011;3(1):1-7.",{"id":18,"text":773,"url":18,"identifiers":18},"Mary EM, Joyce B, Lissa C, Patricia C, Lindsay DJ, Jennifer P, Melissa S, Katie EZ et al. Effect of High-Fidelity Simulation on Pediatric Nursing Students’ Anxiety. Clinical Simulation in Nursing. 2012;8(9):e419-e428.",{"id":775,"createTime":776,"updateTime":776,"relativeEntities":777,"slug":778,"properties":779,"entityType":47,"verifyStatus":17,"verifyTime":789,"verifyNote":49,"syncStatus":17,"languages":790,"translateLanguages":18,"viewCount":19,"primaryUrl":791,"fullTextUrl":792,"authors":793,"publicationType":78,"publisherRelationship":807,"citationCount":19,"citationInfo":821,"publishDate":823,"publishYear":404,"citationAnalyzeStatus":97,"lastCitationAnalyze":789,"indexDatabases":18,"openAccess":18,"references":824,"isForceReanalyzing":131},"1c6e82bf-977d-41dc-b0bf-0b1947460db9","2025-07-13T16:04:52.600+00:00",[],"High-dose-chemotherapy-and-autologous-hematopoietic-stem-cell-rescue-for-children-with-high-risk-neuroblastoma-Two-Case-Reports",{"keywords":780,"gsPaper":781,"abstract":783,"title":785,"doi":787},{},{"VOID":782},"[\"3778321239528417059\"]",{"VI":784,"EN":784},"Introduction: High-risk neuroblastoma is a childhood malignancy with a poor prognosis. Gradual improvements in survival have correlated with therapeutic intensity, and the ability to harvest, process, and store autologous hematopoietic stem cells has allowed for dose intensification beyond marrow tolerance.\r\nCase: We report two cases diagnosed with high-risk neuroblastoma. The first case involved a 5-year-old male with a large heterogeneous tumor in his left adrenal gland and metastasis in the bone marrow and brain. The second case was a 5-year-old female with a localized tumor in her right kidney and NMYC positive. Both cases were treated with the SIOPEN protocol, starting with 8 courses of RAPID COJECT. After partial response, stem cells were collected, followed by primary tumor resection, high-dose chemotherapy with autologous stem cell rescue, radiation, and retinoic acid treatment.\r\nConclusion: This report is the initial documentation of autologous stem cell transplant for high-risk neuroblastoma. Despite involving only two patients, the results indicated that stem cell transplant was safe and effective. We aim to implement this treatment for more cases of high-risk neuroblastoma and report further findings with a larger cohort.",{"VI":786,"EN":786},"High dose chemotherapy and autologous hematopoietic stem cell rescue for children with high risk neuroblastoma: Two Case Reports",{"VOID":788},"10.38103\u002Fjcmhch.2020.62.16","2025-07-13T16:04:52.599+00:00",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F2178","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F2178\u002F1915",[794,800],{"id":795,"sortIndex":19,"researcher":18,"roles":796,"affiliations":797,"properties":798},"bcbbc479-9cf1-4238-9e15-57a93f6d1fd8",[],[],{"title":799},{"EN":173},{"id":801,"sortIndex":72,"researcher":18,"roles":802,"affiliations":803,"properties":804},"49ef3693-29fc-41ab-a66f-2dbfa72bfba1",[],[],{"title":805},{"EN":806},"Tran Kiem Hao, Chau Van Ha, Phan Canh Duy, Dong Si Sang, Phan Thi Thuy Hoa, Ho Huu Thien, Nguyen Thi My Linh, Pham Nhu Hiep",{"url":18,"publisher":808,"properties":816},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":809,"slug":10,"properties":810,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":813,"manageAffiliations":814,"indexDatabases":815,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":811,"title":812},{"VOID":13},{"VOID":15},[],[],[],{"pages":817,"issue":819},{"VOID":818},"93-98",{"VOID":820},"62",{"total":19,"publishYear":404,"statisticByYear":822},{},"2020-06-20",[825,827,829,831,833,835,837,839,841,843],{"id":18,"text":826,"url":18,"identifiers":18},"Trahair TN, Vowels MR, Johnston K, Cohn RJ, Russell SJ, Neville KA, et al. Long-term outcomes in children with high-risk neuroblastoma treated with autologous stem cell transplantation. Bone Marrow Transplant. 2007; 40: 741 - 6.",{"id":18,"text":828,"url":18,"identifiers":18},"Lau SCD, Unni MNM, Teh KH, Aziz MA, Muda Z, Thomas SA, et al. Autologous stem cell transplantation following high-dose chemotherapy in children with high-risk neuroblastoma: Practicality in resource-limited countries. Pediatr Blood Cancer. 2020; 67: e28176.",{"id":18,"text":830,"url":18,"identifiers":18},"Elzembely MM, Park JR, Riad KF, Sayed HA, Pinto N, Carpenter PA, et al. Acute complications after high-dose chemotherapy and stem-cell rescue in pediatric patients with high-risk neuroblastoma treated in countries with different resources. J Glob Oncol. 2018; 4: 1 - 12.",{"id":18,"text":832,"url":18,"identifiers":18},"Fish JD, Grupp SA. Stem cell transplantation for neuroblastoma. Bone Marrow Transplant. 2008; 41: 159 - 65.",{"id":18,"text":834,"url":18,"identifiers":18},"Matthay KK, Villablanca JG, Seeger RC, Stram DO, Harris RE, Ramsay NK, et al. Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children’s Cancer Group. N Engl J Med. 1999; 341: 1165 - 73.",{"id":18,"text":836,"url":18,"identifiers":18},"Soni S, Pai V, Gross TG, Ranalli M. Busulfan and melphalan as consolidation therapy with autologous peripheral blood stem cell transplantation following Children’s Oncology Group (COG) induction platform for high-risk neuroblastoma: early results from a single institution. Pediatr Transplant. 2014; 18: 217 - 20.",{"id":18,"text":838,"url":18,"identifiers":18},"Yalcin B, Kremer LC, Caron HN, van Dalen EC. High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma. Cochrane Database Syst Rev. 2013: CD006301.",{"id":18,"text":840,"url":18,"identifiers":18},"Parikh NS, Howard SC, Chantada G, Israels T, Khattab M, Alcasabas P, et al. SIOP-PODC adapted risk stratification and treatment guidelines: Recommendations for neuroblastoma in low- and middle-income settings. Pediatr Blood Cancer. 2015; 62: 1305 - 16.",{"id":18,"text":842,"url":18,"identifiers":18},"Peinemann F, van Dalen EC, Enk H, Berthold F. Retinoic acid postconsolidation therapy for high-risk neuroblastoma patients treated with autologous haematopoietic stem cell transplantation. Cochrane Database Syst Rev. 2017; 8: CD010685.",{"id":18,"text":844,"url":18,"identifiers":18},"Ali MY, Oyama Y, Monreal J, Winter JN, Tallman MS, Williams SF, et al. Ideal or actual body weight to calculate CD34+ cell doses for autologous hematopoietic stem cell transplantation? Bone Marrow Transplant. 2003; 31: 861 - 4.",{"id":846,"createTime":847,"updateTime":847,"relativeEntities":848,"slug":849,"properties":850,"entityType":47,"verifyStatus":17,"verifyTime":860,"verifyNote":49,"syncStatus":17,"languages":861,"translateLanguages":18,"viewCount":19,"primaryUrl":862,"fullTextUrl":863,"authors":864,"publicationType":78,"publisherRelationship":884,"citationCount":19,"citationInfo":900,"publishDate":903,"publishYear":901,"citationAnalyzeStatus":97,"lastCitationAnalyze":860,"indexDatabases":18,"openAccess":18,"references":904,"isForceReanalyzing":131},"23218da7-4d61-4767-84ca-e6124f9e094a","2025-07-13T14:59:55.145+00:00",[],"Assessment-of-infection-rate-during-the-induction-phase-in-acute-leukemia-patients",{"keywords":851,"gsPaper":852,"abstract":854,"title":856,"doi":858},{},{"VOID":853},"[\"5114668587056434316\"]",{"EN":855},"Introduction: Acute leukemia is the most common cancer in children, and infections is one of the major complications during treatment. This study aimed to assess the incidence of infections during the induction phase of acute leukemia treatment.\nMethods: Patients diagnosed and treated for acute leukemia between December 2022 and July 2024 at the Pediatric Center, Hue Central Hospital, were included in this study. Data were extracted from medical records and analyzed using SPSS v.18.0 (IBM Corp., Armonk, NY, USA).\nResults: A total of 55 patients with acute leukemia were included in the study, comprising 13 cases of acute myeloid leukemia (AML), 29 cases of high-risk acute lymphoblastic leukemia (HR-ALL), and 13 cases of standard-risk acute lymphoblastic leukemia (SR-ALL). Infections occurred in 85.5% of patients during the induction phase, with the highest incidence observed in the first three weeks of treatment (95.7%). Patients with AML had a significantly higher infection rate compared to those with ALL (92.3% vs. 83.3%, p < 0.01). The most common site of infection was the oropharynx (29.8%), followed by the gastrointestinal tract (27.7%), lower respiratory tract (23.4%), and bloodstream (sepsis) (21.3%). Urinary tract infections were the least common (2.1%). Additionally, 21.3% of patients experienced infections involving two or more organ systems. The rate of positive blood cultures was 17.0%, while positive fungal cultures accounted for 4.2%. The success rate of infection treatment was 89.4%, with a mortality rate of 10.6%.\nConclusions: Infections are highly prevalent during the induction phase of acute leukemia treatment. Early detection and prompt administration of antibiotics are critical to managing infections and improving patient outcomes.\n ",{"EN":857},"Assessment of infection rate during the induction phase in acute leukemia patients",{"VOID":859},"10.38103\u002Fjcmhch.17.5.10","2025-07-13T14:59:55.144+00:00",[148],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F2350","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F2350\u002F2111",[865,871,877],{"id":866,"sortIndex":19,"researcher":18,"roles":867,"affiliations":868,"properties":869},"8ebdf576-6a30-4031-be8f-98f34f5aea42",[],[],{"title":870},{"EN":173},{"id":872,"sortIndex":72,"researcher":18,"roles":873,"affiliations":874,"properties":875},"166a5908-9ce1-4ce4-b90d-8bf0f9e205ee",[],[],{"title":876},{"EN":471},{"id":878,"sortIndex":57,"researcher":18,"roles":879,"affiliations":880,"properties":881},"c75cc3da-8692-4963-a44c-966fc282b227",[],[],{"title":882},{"EN":883},"Truong Thi Minh Tam",{"url":18,"publisher":885,"properties":893},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":886,"slug":10,"properties":887,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":890,"manageAffiliations":891,"indexDatabases":892,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":888,"title":889},{"VOID":13},{"VOID":15},[],[],[],{"volume":894,"pages":896,"issue":898},{"VOID":895},"17",{"VOID":897},"",{"VOID":899},"5",{"total":19,"publishYear":901,"statisticByYear":902},2025,{},"2025-07-06",[905,907,909,911,913,915,917,919,921,923,925,927,929,931,933,935,937,939,941,943,945],{"id":18,"text":906,"url":18,"identifiers":18},"Malczewska M, Kosmider K, Bednarz K, Ostapinska K, Lejman M, Zawitkowska J. Recent Advances in Treatment Options for Childhood Acute Lymphoblastic Leukemia. Cancers (Basel). 2022; 14(8). https:\u002F\u002Fdoi.org\u002F10.3390\u002Fcancers14082021",{"id":18,"text":908,"url":18,"identifiers":18},"Zajac-Spychala O, Skalska-Sadowska J, Wachowiak J, Szmydki-Baran A, Hutnik L, Matysiak M, et al. Infections in children with acute myeloid leukemia: increased mortality in relapsed\u002Frefractory patients. Leuk Lymphoma. 2019; 60(12): 3028-3035. https:\u002F\u002Fdoi.org\u002F10.1080\u002F10428194.2019.1616185",{"id":18,"text":910,"url":18,"identifiers":18},"Inaba H, Mullighan CG. Pediatric acute lymphoblastic leukemia. Haematologica. 2020; 105(11): 2524-2539. https:\u002F\u002Fdoi.org\u002F10.3324\u002Fhaematol.2020.247031",{"id":18,"text":912,"url":18,"identifiers":18},"Pui CH. Precision medicine in acute lymphoblastic leukemia. Front Med. 2020; 14(6): 689-700. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11684-020-0759-8",{"id":18,"text":914,"url":18,"identifiers":18},"Inaba H, Pui CH. Advances in the Diagnosis and Treatment of Pediatric Acute Lymphoblastic Leukemia. J Clin Med. 2021; 10(9). https:\u002F\u002Fdoi.org\u002F10.3390\u002Fjcm10091926",{"id":18,"text":916,"url":18,"identifiers":18},"Lehrnbecher T, Robinson P, Fisher B, Alexander S, Ammann RA, Beauchemin M, et al. Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update. J Clin Oncol. 2017; 35(18): 2082-2094. https:\u002F\u002Fdoi.org\u002F10.1200\u002FJCO.2016.71.7017",{"id":18,"text":918,"url":18,"identifiers":18},"Logan C, Koura D, Taplitz R. Updates in infection risk and management in acute leukemia. Hematology Am Soc Hematol Educ Program. 2020; 2020(1): 135-139. https:\u002F\u002Fdoi.org\u002F10.1182\u002Fhematology.2020000098",{"id":18,"text":920,"url":18,"identifiers":18},"Cennamo F, Masetti R, Largo P, Argentiero A, Pession A, Esposito S. Update on Febrile Neutropenia in Pediatric Oncological Patients Undergoing Chemotherapy. Children (Basel). 2021; 8(12). https:\u002F\u002Fdoi.org\u002F10.3390\u002Fchildren8121086",{"id":18,"text":922,"url":18,"identifiers":18},"Brown P, Inaba H, Annesley C, Beck J, Colace S, Dallas M, et al. Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2020; 18(1): 81-112. https:\u002F\u002Fdoi.org\u002F10.6004\u002Fjnccn.2020.0001",{"id":18,"text":924,"url":18,"identifiers":18},"Hastings C, Torkildson J, Agrawal A, Acute Leukemias. Handbook of Pediatric Hematology and Oncology. 2021, Children's Hospital & Research Center Oakland, John Wiley & Son Ltd. 120-160.",{"id":18,"text":926,"url":18,"identifiers":18},"Bộ Y Tế. Hướng dẫn chẩn đoán và điều trị một số bệnh lý huyết học 2022.",{"id":18,"text":928,"url":18,"identifiers":18},"Hutchinson RJ, Gaynon PS, Sather H, Bertolone SJ, Cooper HA, Tannous R, et al. Intensification of therapy for children with lower-risk acute lymphoblastic leukemia: long-term follow-up of patients treated on Children's Cancer Group Trial 1881. J Clin Oncol. 2003; 21(9): 1790-7. https:\u002F\u002Fdoi.org\u002F10.1200\u002FJCO.2003.03.009",{"id":18,"text":930,"url":18,"identifiers":18},"Nachman J, Sather HN, Cherlow JM, Sensel MG, Gaynon PS, Lukens JN, et al. Response of children with high-risk acute lymphoblastic leukemia treated with and without cranial irradiation: a report from the Children's Cancer Group. J Clin Oncol. 1998; 16(3): 920-30. https:\u002F\u002Fdoi.org\u002F10.1200\u002FJCO.1998.16.3.920",{"id":18,"text":932,"url":18,"identifiers":18},"Tran Thi Thuy. Nghiên cứu đặc điểm nhiễm trùng ở bệnh nhi lơxêmi cấp sau điều trị tấn công tại Viện Huyết Học- Truyền máu Trung ương, giai đoạn 2019-2024. Luận Văn Thạc Sĩ Y Khoa, Trường Đại Học Y Hà Nội. 2014.",{"id":18,"text":934,"url":18,"identifiers":18},"Zhu Y, Yang R, Cai J, Yu J, Tang Y, Chen Y, et al. Septicemia after chemotherapy for childhood acute lymphoblastic leukemia in China: A multicenter study CCCG-ALL-2015. Cancer Med. 2020; 9(6): 2113-2121. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fcam4.2889",{"id":18,"text":936,"url":18,"identifiers":18},"Rajeswari B, Sukumaran R, Guruprasad C. Infections during induction chemotherapy in children with acute lymphoblastic leukemia- Profile and Outcomes: Experience from a Cancer Center in South India. Indian Journal of Medical and Paediatric Oncology. 2018; 39: 188.",{"id":18,"text":938,"url":18,"identifiers":18},"Sayed HA, El-Mahallawy HA, Kaddah AM, Ismael HT, Talaat SM. Profile of infections in newly diagnosed patients with acute leukemia during the induction phase of treatment. J Egypt Natl Canc Inst. 2009; 21(4): 315-22.",{"id":18,"text":940,"url":18,"identifiers":18},"McCormick M, Richardson T, Rapkin L, Kalpatthi R. Risk Factors for Readmission Following Febrile Neutropenia in Pediatric Oncology Patients. J Pediatr Hematol Oncol. 2023; 45(4): e496-e501. https:\u002F\u002Fdoi.org\u002F10.1097\u002FMPH.0000000000002585",{"id":18,"text":942,"url":18,"identifiers":18},"Carlesse F, Sousa AV. Infections in children and adolescents with acute leukemia. EJC Paediatric Oncology. 2024; 3: 100142.",{"id":18,"text":944,"url":18,"identifiers":18},"Meir HM, Balawi IA. Fever and granulocytopenia in children with acute lymphoblastic leukemia under induction therapy. Saudi Med J. 2001; 22 (5): 423-427.",{"id":18,"text":946,"url":18,"identifiers":18},"Bakhshi S, Padmanjali KS, Arya LS. Infections in childhood acute lymphoblastic leukemia: an analysis of 222 febrile neutropenic episodes. Pediatr Hematol Oncol. 2008; 25(5): 385-92. https:\u002F\u002Fdoi.org\u002F10.1080\u002F08880010802106564",{"id":948,"createTime":949,"updateTime":949,"relativeEntities":950,"slug":951,"properties":952,"entityType":47,"verifyStatus":17,"verifyTime":963,"verifyNote":49,"syncStatus":17,"languages":964,"translateLanguages":18,"viewCount":19,"primaryUrl":965,"fullTextUrl":966,"authors":967,"publicationType":78,"publisherRelationship":1003,"citationCount":18,"citationInfo":18,"publishDate":1017,"publishYear":1018,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":1019,"openAccess":18,"references":1020,"isForceReanalyzing":131},"ac8bb6a4-b086-4c06-aa41-73e14b8dd1c6","2026-03-24T09:00:17.742+00:00",[],"K%E1%BA%BFt-qu%E1%BA%A3-%C4%91i%E1%BB%81u-tr%E1%BB%8B-suy-gi%C3%A3n-t%C4%A9nh-m%E1%BA%A1ch-n%C3%B4ng-chi-d%C6%B0%E1%BB%9Bi-b%E1%BA%B1ng-ph%C6%B0%C6%A1ng-ph%C3%A1p-%C4%91%E1%BB%91t-s%C3%B3ng-cao-t%E1%BA%A7n-t%E1%BA%A1i-B%E1%BB%87nh-vi%E1%BB%87n-Trung-%C6%B0%C6%A1ng-Hu%E1%BA%BF",{"keywords":953,"abstract":955,"title":958,"doi":961},{"VI":954},"Đốt sóng cao tần,suy giãn tĩnh mạch nông chi dưới",{"VI":956,"EN":957},"Mục tiêu: Mô tả đặc điểm lâm sàng, cận lâm sàng của bệnh nhân suy giãn tĩnh mạch nông chi dưới và đánh giá kết quả điều trị suy giãn tĩnh mạch nông chi dưới bằng phương pháp đốt sóng cao tần.\r\nPhương pháp: Nghiên cứu mô tả cắt ngang 59 bệnh nhân bị suy giãn tĩnh mạch nông chi dưới được chẩn đoán bằng siêu âm Doppler mạch máu từ tháng 10\u002F2018 đến tháng 9\u002F2019.\r\nKết quả: Độ tuổi tuổi trung bình 57,3±11,10, tỷ lệ nữ\u002Fnam 1,95\u002F1. Có 10 chân được điều trị bằng phương pháp đốt sóng cao tần đơn thuần, 15 chân phối hợp tiêm xơ bọt, 57 chân phối hợp phẫu thuật Muller và 8 chân phối hợp cả 3 phương pháp trên. Sau điều trị, 100% các trường hợp tĩnh mạch được can thiệp teo nhỏ và không có dòng chảy bên trong. Kết quả bước đầu khá tốt, triệu chứng lâm sàng cải thiện, không có biến chứng nặng trong quá trình thao tác.\r\nKết luận: Phương pháp đốt sóng cao tần (RFA: Radiofrequency ablation) có hiệu quả trong điều trị suy giãn tĩnh mạch nông chi dưới với các ưu điểm sau: tỷ lệ biến chứng thấp, ít đau, thẩm mỹ và cải thiện triệu chứng lâm sàng. Sự phối hợp các phương pháp hỗ trợ như tiêm xơ bọt và phẫu thuật Muller luôn được đặt ra để mang lại kết quả tốt cho người bệnh.","Objective: To describe clinical and subclinical characteristics of patient with varicose veins and to evaluate the result of treatment of varicose veins by endovenous radiofrequency ablation.\r\nMethods: A cross-sectional study on 59 patients with varicose veins that were diagnosed by Doppler ultrasound from 10\u002F2018 to 9\u002F2019.\r\nResults: Mean age was 57,3±11,10, female and male ratio was 1,95\u002F1. There were 10 limbs treated with endovenous radiofrequency ablation unique, 15 limbs associated with sclerotherapy, 57 limbs associated with phlebectomy Muller and 8 limbs associated 3 methods. After treatment, 100% of cases presented sclerosis veins and no intravenous flow. The initial result were quite good, clinical symptoms improve, and there were no serious complications related to the procedure.\r\nConclusion: RFA procedure is effective in treating varicose veins of the lower limbs with the following advantages: Low complication rate, less pain, aesthetics and clinical symptom improvement. The combination of supportive methods such as foam sclerotherapy and phlebectomy Muller is always in place to bring good results to patients.",{"VI":959,"EN":960},"Kết quả điều trị suy giãn tĩnh mạch nông chi dưới bằng phương pháp đốt sóng cao tần tại Bệnh viện Trung ương Huế","Outcomes of varicose veins treated by endovenous radiofrequency ablation in Hue central hospital",{"VOID":962},"10.38103\u002Fjcmhch.2021.68.7","2026-03-24T09:00:17.741+00:00",[51],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F1128","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F1128\u002F947",[968,975,982,989,996],{"id":969,"sortIndex":253,"researcher":18,"roles":970,"affiliations":971,"properties":972},"f7dca663-4b29-4170-849b-03db296ca5f7",[],[],{"title":973},{"VI":974},"Thị Thanh Vân Đặng",{"id":976,"sortIndex":72,"researcher":18,"roles":977,"affiliations":978,"properties":979},"0da00160-204c-427a-b1cd-8df0e1adc891",[],[],{"title":980},{"VI":981},"Công Thảo Trịnh",{"id":983,"sortIndex":19,"researcher":18,"roles":984,"affiliations":985,"properties":986},"41bd821c-8104-4ba8-a7a6-81795556d0f7",[],[],{"title":987},{"VI":988},"Thị Cẩm Vân Nguyễn",{"id":990,"sortIndex":154,"researcher":18,"roles":991,"affiliations":992,"properties":993},"fb22c39b-58c7-4fa7-b195-d01d6f6865d5",[],[],{"title":994},{"VI":995},"Thị Thủy Đào",{"id":997,"sortIndex":57,"researcher":18,"roles":998,"affiliations":999,"properties":1000},"236504ff-5a91-4296-b384-87f8e0c622ec",[],[],{"title":1001},{"VI":1002},"Hoàng Minh Nguyễn",{"url":18,"publisher":1004,"properties":1012},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1005,"slug":10,"properties":1006,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1009,"manageAffiliations":1010,"indexDatabases":1011,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":1007,"title":1008},{"VOID":13},{"VOID":15},[],[],[],{"pages":1013,"issue":1015},{"VOID":1014},"48-53",{"VOID":1016},"68","2021-04-27",2021,[],[1021,1023,1025,1027,1029,1031,1033,1035,1037,1039,1041],{"id":18,"text":1022,"url":18,"identifiers":18},"Nguyễn Trung Anh (2017). Nghiên cứu đặc điểm lâm sàng, cận lâm sàng, kết quả điều trị suy tĩnh mạch chi dưới mạn tính của phương pháp gây xơ bằng thuốc và Laser nội tĩnh mạch. Luận án tiến sĩ y học, Viện nghiên cứu khoa học y dược lâm sàng 108.",{"id":18,"text":1024,"url":18,"identifiers":18},"Trần Hoài Ân (2018). Nghiên cứu điều trị bệnh lý suy giãn tĩnh mạch nông chi dưới bằng phẫu thuật Muller kết hợp phương pháp Laser nội tĩnh mạch. Luận án chuyên khoa II, Trường đại học Y dược Huế.",{"id":18,"text":1026,"url":18,"identifiers":18},"Cao Việt Cường (2012). Nghiên cứu ứng dụng phương pháp gây xơ tĩnh mạch bằng chất tạo bọt dưới hướng dẫn của siêu âm trong điều trị suy tĩnh mạch mạn tính chi dưới. Luận văn thạc sĩ y học, Trường đại học Y Hà Nội.",{"id":18,"text":1028,"url":18,"identifiers":18},"Bùi Văn Dũng, Nguyễn Minh Đức, Đặng Thị Việt Hà và cộng sự (2017). Đặc điểm lâm sàng và siêu âm Doppler ở bệnh nhân suy tĩnh mạch hiển lớn mạn tính có chỉ định điều trị Laser nội mạch tại Bệnh viện Lão khoa Trung ương. Tạp chí Y dược học quân sự, (Số 2), 81-86.",{"id":18,"text":1030,"url":18,"identifiers":18},"Hồ Khánh Đức, Cao Văn Thịnh, Nguyễn Công Minh và cộng sự (2014). Điều trị suy giãn tĩnh mạch nông chi dưới bằng phương pháp laser nội tĩnh mạch (kết quả sau 2 năm theo dõi). Y học Thành phố Hồ Chí Minh, Tập 18, (Số 1), 418-423.",{"id":18,"text":1032,"url":18,"identifiers":18},"Nguyễn Phước Bảo Quân (2008). Siêu âm Doppler mạch máu chi dưới. Siêu âm Doppler mạch máu, Nhà xuất bản Đại học Y Dược Huế, Tập 2, 553-554.",{"id":18,"text":1034,"url":18,"identifiers":18},"Nguyễn Thị Cẩm Vân, Trần Hoài Ân (2016). Đánh giá kết quả điều trị Laser tĩnh mạch trong bệnh lý suy giãn tĩnh mạch nông hai chi dưới tại Bệnh viện Trung ương Huế. Tạp chí Y học lâm sàng, (Số 39), 67-72.",{"id":18,"text":1036,"url":18,"identifiers":18},"Beebe-Dimmer JL, Pfeifer JR, Engle JS, et al. (2005). The epidemiology of chronic venous insufficiency and varicose veins. Annals of Epidemiology, 15(3), 175-184.",{"id":18,"text":1038,"url":18,"identifiers":18},"Lawaetz M, Serup J, Lawaetz B, et al. (2017). Comparison of endovenous radiofrequency ablation, laser ablation, foam sclerotherapy, and surgical stripping for great saphenous varicose veins: Extended 5-year follow-up of a RCT. International Angiology, 36(3), 281-288.",{"id":18,"text":1040,"url":18,"identifiers":18},"Lin F, et al. (2015). The management of varicose veins. International Surgery, 100(1), 185-189.",{"id":18,"text":1042,"url":18,"identifiers":18},"Rasmussen LH, Lawaetz M, Bjoern L, et al. (2011). Randomized clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy, and surgical stripping for great saphenous varicose veins. British Journal of Surgery, 98(8), 1079-1087."]