[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_f5b73086-61b4-4d2e-b46b-1b8ffe84d1ca":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:f5b73086-61b4-4d2e-b46b-1b8ffe84d1ca,\"}":25},{"code":4,"data":5,"meta":18},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":20,"manageAffiliations":21,"indexDatabases":22,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},"f5b73086-61b4-4d2e-b46b-1b8ffe84d1ca","2025-07-10T16:15:33.506+00:00","2026-03-24T09:00:17.763+00:00",[],"T%E1%BA%A1p-ch%C3%AD-Y-h%E1%BB%8Dc-l%C3%A2m-s%C3%A0ng-B%E1%BB%87nh-vi%E1%BB%87n-Trung-%C6%AF%C6%A1ng-Hu%E1%BA%BF",{"issn":12,"title":14},{"VOID":13},"30304733",{"VOID":15},"Tạp chí Y học lâm sàng Bệnh viện Trung Ương Huế","PUBLISHER","PENDING",null,0,[],[],[],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome","JOURNAL",{"meta":26,"data":28},{"total":27},"14",[29,134,196,281,358,652,713,831,939,1042],{"id":30,"createTime":31,"updateTime":31,"relativeEntities":32,"slug":33,"properties":34,"entityType":45,"verifyStatus":17,"verifyTime":46,"verifyNote":47,"languages":48,"translateLanguages":18,"viewCount":19,"primaryUrl":50,"fullTextUrl":51,"authors":52,"publicationType":92,"publisherRelationship":93,"citationCount":18,"citationInfo":18,"publishDate":107,"publishYear":108,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":109,"openAccess":18,"references":110,"isForceReanalyzing":133},"ac8bb6a4-b086-4c06-aa41-73e14b8dd1c6","2026-03-24T09:00:17.742+00:00",[],"K%E1%BA%BFt-qu%E1%BA%A3-%C4%91i%E1%BB%81u-tr%E1%BB%8B-suy-gi%C3%A3n-t%C4%A9nh-m%E1%BA%A1ch-n%C3%B4ng-chi-d%C6%B0%E1%BB%9Bi-b%E1%BA%B1ng-ph%C6%B0%C6%A1ng-ph%C3%A1p-%C4%91%E1%BB%91t-s%C3%B3ng-cao-t%E1%BA%A7n-t%E1%BA%A1i-B%E1%BB%87nh-vi%E1%BB%87n-Trung-%C6%B0%C6%A1ng-Hu%E1%BA%BF",{"abstract":35,"title":38,"keywords":41,"doi":43},{"VI":36,"EN":37},"Mục tiêu: Mô tả đặc điểm lâm sàng, cận lâm sàng của bệnh nhân suy giãn tĩnh mạch nông chi dưới và đánh giá kết quả điều trị suy giãn tĩnh mạch nông chi dưới bằng phương pháp đốt sóng cao tần.\r\nPhương pháp: Nghiên cứu mô tả cắt ngang 59 bệnh nhân bị suy giãn tĩnh mạch nông chi dưới được chẩn đoán bằng siêu âm Doppler mạch máu từ tháng 10\u002F2018 đến tháng 9\u002F2019.\r\nKết quả: Độ tuổi tuổi trung bình 57,3±11,10, tỷ lệ nữ\u002Fnam 1,95\u002F1. Có 10 chân được điều trị bằng phương pháp đốt sóng cao tần đơn thuần, 15 chân phối hợp tiêm xơ bọt, 57 chân phối hợp phẫu thuật Muller và 8 chân phối hợp cả 3 phương pháp trên. Sau điều trị, 100% các trường hợp tĩnh mạch được can thiệp teo nhỏ và không có dòng chảy bên trong. Kết quả bước đầu khá tốt, triệu chứng lâm sàng cải thiện, không có biến chứng nặng trong quá trình thao tác.\r\nKết luận: Phương pháp đốt sóng cao tần (RFA: Radiofrequency ablation) có hiệu quả trong điều trị suy giãn tĩnh mạch nông chi dưới với các ưu điểm sau: tỷ lệ biến chứng thấp, ít đau, thẩm mỹ và cải thiện triệu chứng lâm sàng. Sự phối hợp các phương pháp hỗ trợ như tiêm xơ bọt và phẫu thuật Muller luôn được đặt ra để mang lại kết quả tốt cho người bệnh.","Objective: To describe clinical and subclinical characteristics of patient with varicose veins and to evaluate the result of treatment of varicose veins by endovenous radiofrequency ablation.\r\nMethods: A cross-sectional study on 59 patients with varicose veins that were diagnosed by Doppler ultrasound from 10\u002F2018 to 9\u002F2019.\r\nResults: Mean age was 57,3±11,10, female and male ratio was 1,95\u002F1. There were 10 limbs treated with endovenous radiofrequency ablation unique, 15 limbs associated with sclerotherapy, 57 limbs associated with phlebectomy Muller and 8 limbs associated 3 methods. After treatment, 100% of cases presented sclerosis veins and no intravenous flow. The initial result were quite good, clinical symptoms improve, and there were no serious complications related to the procedure.\r\nConclusion: RFA procedure is effective in treating varicose veins of the lower limbs with the following advantages: Low complication rate, less pain, aesthetics and clinical symptom improvement. The combination of supportive methods such as foam sclerotherapy and phlebectomy Muller is always in place to bring good results to patients.",{"EN":39,"VI":40},"Outcomes of varicose veins treated by endovenous radiofrequency ablation in Hue central hospital","Kết quả điều trị suy giãn tĩnh mạch nông chi dưới bằng phương pháp đốt sóng cao tần tại Bệnh viện Trung ương Huế",{"VI":42},"Đốt sóng cao tần,suy giãn tĩnh mạch nông chi dưới",{"VOID":44},"10.38103\u002Fjcmhch.2021.68.7","PUBLICATION","2026-03-24T09:00:17.741+00:00","Author affiliation is blank",[49],"VI","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F1128","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F1128\u002F947",[53,60,68,76,84],{"id":54,"sortIndex":19,"researcher":18,"roles":55,"affiliations":56,"properties":57},"41bd821c-8104-4ba8-a7a6-81795556d0f7",[],[],{"title":58},{"VI":59},"Thị Cẩm Vân Nguyễn",{"id":61,"sortIndex":62,"researcher":18,"roles":63,"affiliations":64,"properties":65},"0da00160-204c-427a-b1cd-8df0e1adc891",1,[],[],{"title":66},{"VI":67},"Công Thảo Trịnh",{"id":69,"sortIndex":70,"researcher":18,"roles":71,"affiliations":72,"properties":73},"236504ff-5a91-4296-b384-87f8e0c622ec",2,[],[],{"title":74},{"VI":75},"Hoàng Minh Nguyễn",{"id":77,"sortIndex":78,"researcher":18,"roles":79,"affiliations":80,"properties":81},"fb22c39b-58c7-4fa7-b195-d01d6f6865d5",3,[],[],{"title":82},{"VI":83},"Thị Thủy Đào",{"id":85,"sortIndex":86,"researcher":18,"roles":87,"affiliations":88,"properties":89},"f7dca663-4b29-4170-849b-03db296ca5f7",4,[],[],{"title":90},{"VI":91},"Thị Thanh Vân Đặng","ARTICLE",{"url":18,"publisher":94,"properties":102},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":95,"slug":10,"properties":96,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":99,"manageAffiliations":100,"indexDatabases":101,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":97,"title":98},{"VOID":13},{"VOID":15},[],[],[],{"issue":103,"pages":105},{"VOID":104},"68",{"VOID":106},"48-53","2021-04-27",2021,[],[111,113,115,117,119,121,123,125,127,129,131],{"id":18,"text":112,"url":18,"identifiers":18},"Nguyễn Trung Anh (2017). Nghiên cứu đặc điểm lâm sàng, cận lâm sàng, kết quả điều trị suy tĩnh mạch chi dưới mạn tính của phương pháp gây xơ bằng thuốc và Laser nội tĩnh mạch. Luận án tiến sĩ y học, Viện nghiên cứu khoa học y dược lâm sàng 108.",{"id":18,"text":114,"url":18,"identifiers":18},"Trần Hoài Ân (2018). Nghiên cứu điều trị bệnh lý suy giãn tĩnh mạch nông chi dưới bằng phẫu thuật Muller kết hợp phương pháp Laser nội tĩnh mạch. Luận án chuyên khoa II, Trường đại học Y dược Huế.",{"id":18,"text":116,"url":18,"identifiers":18},"Cao Việt Cường (2012). Nghiên cứu ứng dụng phương pháp gây xơ tĩnh mạch bằng chất tạo bọt dưới hướng dẫn của siêu âm trong điều trị suy tĩnh mạch mạn tính chi dưới. Luận văn thạc sĩ y học, Trường đại học Y Hà Nội.",{"id":18,"text":118,"url":18,"identifiers":18},"Bùi Văn Dũng, Nguyễn Minh Đức, Đặng Thị Việt Hà và cộng sự (2017). Đặc điểm lâm sàng và siêu âm Doppler ở bệnh nhân suy tĩnh mạch hiển lớn mạn tính có chỉ định điều trị Laser nội mạch tại Bệnh viện Lão khoa Trung ương. Tạp chí Y dược học quân sự, (Số 2), 81-86.",{"id":18,"text":120,"url":18,"identifiers":18},"Hồ Khánh Đức, Cao Văn Thịnh, Nguyễn Công Minh và cộng sự (2014). Điều trị suy giãn tĩnh mạch nông chi dưới bằng phương pháp laser nội tĩnh mạch (kết quả sau 2 năm theo dõi). Y học Thành phố Hồ Chí Minh, Tập 18, (Số 1), 418-423.",{"id":18,"text":122,"url":18,"identifiers":18},"Nguyễn Phước Bảo Quân (2008). Siêu âm Doppler mạch máu chi dưới. Siêu âm Doppler mạch máu, Nhà xuất bản Đại học Y Dược Huế, Tập 2, 553-554.",{"id":18,"text":124,"url":18,"identifiers":18},"Nguyễn Thị Cẩm Vân, Trần Hoài Ân (2016). Đánh giá kết quả điều trị Laser tĩnh mạch trong bệnh lý suy giãn tĩnh mạch nông hai chi dưới tại Bệnh viện Trung ương Huế. Tạp chí Y học lâm sàng, (Số 39), 67-72.",{"id":18,"text":126,"url":18,"identifiers":18},"Beebe-Dimmer JL, Pfeifer JR, Engle JS, et al. (2005). The epidemiology of chronic venous insufficiency and varicose veins. Annals of Epidemiology, 15(3), 175-184.",{"id":18,"text":128,"url":18,"identifiers":18},"Lawaetz M, Serup J, Lawaetz B, et al. (2017). Comparison of endovenous radiofrequency ablation, laser ablation, foam sclerotherapy, and surgical stripping for great saphenous varicose veins: Extended 5-year follow-up of a RCT. International Angiology, 36(3), 281-288.",{"id":18,"text":130,"url":18,"identifiers":18},"Lin F, et al. (2015). The management of varicose veins. International Surgery, 100(1), 185-189.",{"id":18,"text":132,"url":18,"identifiers":18},"Rasmussen LH, Lawaetz M, Bjoern L, et al. (2011). Randomized clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy, and surgical stripping for great saphenous varicose veins. British Journal of Surgery, 98(8), 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Tuberculosis (TB) remains a major global health challenge, with early and accurate diagnosis being critical for effective disease control. Traditional acid-fast bacilli (AFB) smear microscopy has limited sensitivity, particularly in smear-negative cases. The advent of molecular techniques, such as the GeneXpert MTB\u002FRIF assay and real-time PCR, has significantly improved the rapid detection of Mycobacterium tuberculosis (MTB) and rifampicin resistance.\r\nMethods: A total of 368 patients suspected of tuberculosis (TB) were analyzed using three diagnostic methods: AFB smear microscopy, GeneXpert MTB\u002FRIF, and real-time PCR. Patient samples were collected from multiple hospital departments and categorized by demographic characteristics. AFB smear was performed using Ziehl-Neelsen staining, while GeneXpert MTB\u002FRIF and real-time PCR were conducted following manufacturer protocols. Sensitivity, specificity, and positivity rates for each diagnostic method were compared to assess their effectiveness in detecting TB cases.\r\nResults: A prospective study at Hue University Hospital (2023-2024) compared TB diagnostic methods in 368 patients. AFB smear microscopy detected only 7.6% of cases, while GeneXpert MTB\u002FRIF and real-time PCR identified 6.3% and 20.5%, respectively. GeneXpert demonstrated 100% sensitivity\u002Fspecificity, outperforming AFB (10% sensitivity) and PCR (82.1% sensitivity, 100% specificity). Most cases were in respiratory (18.4%) and infectious disease (16.1%) departments.\r\nConclusion: Findings highlight the critical role of molecular methods like GeneXpert and PCR in improving TB detection and urge their integration into routine screening to optimize early diagnosis and treatment.",{"EN":368},"Assessing the effectiveness of AFB smear versus GeneXpert MTB\u002FRIF and real-time PCR in diagnosing tuberculosis at Hue University of Medicine and Pharmacy Hospital",{"VOID":370},"[\"14405857738641804732\"]",{"VOID":372},"10.38103\u002Fjcmhch.17.2.13","VERIFIED","2025-07-15T00:14:28.425+00:00","Auto 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Global tuberculosis report 2022. 2022 [cited 2025 19\u002F02]; Available from: https:\u002F\u002Fwww.who.int\u002Fpublications\u002Fi\u002Fitem\u002F9789240061729",{"id":18,"text":629,"url":18,"identifiers":18},"Pai M, Schito M. Tuberculosis diagnostics in 2015: landscape, priorities, needs, and prospects. J Infect Dis. 2015;211 Suppl 2(Suppl 2): S21-8. https:\u002F\u002Fdoi.org\u002F10.1093\u002Finfdis\u002Fjiu803",{"id":18,"text":631,"url":18,"identifiers":18},"Horne DJ, Kohli M, Zifodya JS, Schiller I, Dendukuri N, Tollefson D, et al. Xpert MTB\u002FRIF and Xpert MTB\u002FRIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2019;6(6):Cd009593. https:\u002F\u002Fdoi.org\u002F10.1002\u002F14651858.CD009593.pub4",{"id":18,"text":633,"url":18,"identifiers":18},"Zeka AN, Tasbakan S, Cavusoglu C. Evaluation of the GeneXpert MTB\u002FRIF assay for rapid diagnosis of tuberculosis and detection of rifampin resistance in pulmonary and extrapulmonary specimens. J Clin Microbiol. 2011;49(12):4138-41. https:\u002F\u002Fdoi.org\u002F10.1128\u002Fjcm.05434-11",{"id":18,"text":635,"url":18,"identifiers":18},"Theron G, Peter J, van Zyl-Smit R, Mishra H, Streicher E, Murray S, et al. Evaluation of the Xpert MTB\u002FRIF assay for the diagnosis of pulmonary tuberculosis in a high HIV prevalence setting. Am J Respir Crit Care Med. 2011;184(1):132-40. https:\u002F\u002Fdoi.org\u002F10.1164\u002Frccm.201101-0056OC",{"id":18,"text":637,"url":18,"identifiers":18},"Lawn SD, Nicol MP. Xpert® MTB\u002FRIF assay: development, evaluation and implementation of a new rapid molecular diagnostic for tuberculosis and rifampicin resistance. 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Clin Microbiol Infect. 2014;20(10):O600-8. https:\u002F\u002Fdoi.org\u002F10.1111\u002F1469-0691.12478",{"id":18,"text":645,"url":18,"identifiers":18},"Lee HS, Kee SJ, Shin JH, Kwon YS, Chun S, Lee JH, et al. Xpert MTB\u002FRIF Assay as a Substitute for Smear Microscopy in an Intermediate-Burden Setting. Am J Respir Crit Care Med. 2019;199(6):784-794. https:\u002F\u002Fdoi.org\u002F10.1164\u002Frccm.201804-0654OC",{"id":18,"text":647,"url":18,"identifiers":18},"Opota O, Senn L, Prod'hom G, Mazza-Stalder J, Tissot F, Greub G, et al. Added value of molecular assay Xpert MTB\u002FRIF compared to sputum smear microscopy to assess the risk of tuberculosis transmission in a low-prevalence country. Clin Microbiol Infect. 2016;22(7):613-9. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.cmi.2016.04.010",{"id":18,"text":649,"url":18,"identifiers":18},"Innes AL, Martinez A, Gao X, Dinh N, Hoang GL, Nguyen TBP, et al. 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Cochrane Database Syst Rev. 2021;3(3):Cd013694. https:\u002F\u002Fdoi.org\u002F10.1002\u002F14651858.CD013694.pub2",{"id":653,"createTime":654,"updateTime":655,"relativeEntities":656,"slug":657,"properties":658,"entityType":45,"verifyStatus":17,"verifyTime":18,"verifyNote":664,"languages":665,"translateLanguages":18,"viewCount":19,"primaryUrl":666,"fullTextUrl":667,"authors":668,"publicationType":92,"publisherRelationship":695,"citationCount":19,"citationInfo":708,"publishDate":276,"publishYear":277,"citationAnalyzeStatus":354,"lastCitationAnalyze":654,"indexDatabases":710,"openAccess":18,"references":711,"isForceReanalyzing":133},"2b32f896-3589-4391-b358-1b6acfff7f09","2025-07-13T16:26:30.098+00:00","2025-07-13T20:13:10.242+00:00",[],"Analysis-of-relapse-childhood-acute-lymphoblastic-leukemia-at-Hue-Cenntral-Hospital-in-Vietnam",{"title":659,"gsPaper":661,"abstract":663},{"EN":660},"Analysis of relapse childhood acute lymphoblastic leukemia at Hue Cenntral Hospital in Vietnam",{"VOID":662},"15994929821384192496",{"EN":144},"Created by PDF Paper Link 2569735",[207],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F1056","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F1056\u002F883",[669,675,681,688],{"id":670,"sortIndex":19,"researcher":18,"roles":671,"affiliations":672,"properties":673},"4e916e1c-ec30-40b7-9863-17eae2820b3b",[],[],{"title":674},{"EN":238},{"id":676,"sortIndex":62,"researcher":18,"roles":677,"affiliations":678,"properties":679},"dd6ff4c2-2c72-4376-9e8b-61a8604841d6",[],[],{"title":680},{"EN":217},{"id":682,"sortIndex":70,"researcher":18,"roles":683,"affiliations":684,"properties":685},"3c3f862b-58bd-445e-ac49-bb64e2101e4c",[],[],{"title":686},{"EN":687},"Chau Van Ha",{"id":689,"sortIndex":78,"researcher":18,"roles":690,"affiliations":691,"properties":692},"a3ed1f14-46fa-4256-a36d-11f17c703c62",[],[],{"title":693},{"EN":694},"Kazuyo Watanabe",{"url":18,"publisher":696,"properties":704},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":697,"slug":10,"properties":698,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":701,"manageAffiliations":702,"indexDatabases":703,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":699,"title":700},{"VOID":13},{"VOID":15},[],[],[],{"issue":705,"pages":706},{"VOID":273},{"VOID":707},"19-24",{"total":19,"publishYear":277,"statisticByYear":709},{},[],[712],{"id":18,"text":144,"url":18,"identifiers":18},{"id":714,"createTime":715,"updateTime":715,"relativeEntities":716,"slug":717,"properties":718,"entityType":45,"verifyStatus":17,"verifyTime":725,"verifyNote":47,"languages":726,"translateLanguages":18,"viewCount":19,"primaryUrl":727,"fullTextUrl":728,"authors":729,"publicationType":92,"publisherRelationship":781,"citationCount":19,"citationInfo":795,"publishDate":798,"publishYear":796,"citationAnalyzeStatus":354,"lastCitationAnalyze":725,"indexDatabases":799,"openAccess":18,"references":800,"isForceReanalyzing":133},"0093c211-86eb-4080-827a-cdbdd6e2240b","2025-07-13T20:03:48.771+00:00",[],"Evaluating-the-effectiveness-of-ketamine-plus-atropin-as-anesthesia-for-intrathecal-chemotherapy-and-bone-marrow-procedure-at-Hue-central-hospital-Vietnam",{"title":719,"gsPaper":721,"abstract":723},{"EN":720},"Evaluating the effectiveness of ketamine plus atropin as anesthesia for intrathecal chemotherapy and bone marrow procedure at Hue central hospital, Vietnam",{"VOID":722},"[\"13305629006173054573\"]",{"EN":724},"ABSTRACTBackground: Ketamine is a phencyclidine and cyclohexamine derivative. Ketamine and atropine have been increasingly used in recent years as an effective form of deep sedation\u002Fanaesthesia in children in developed countries, but not in developing countries like Vietnam. Objective: This pioneer trial aimed to evaluate the effectiveness of using ketamine plus atropine as anaesthetic agents for paediatric oncology procedures. From this study, we establish a protocol for anaesthesia in paediatric oncology procedures. Methods: A descriptive and prospective study on 223 paediatric patients of both sexes (129 males and 94 females) aged 7.2 months to 15 years (mean age: 4.0 ± 3.4 years) and with body weight between 6.5 to 55 kg (mean weight: 15.3 ± 6.2 kg) was carried out from January 2015 to June 2019. The patients had been diagnosed with acute leukaemia, lymphoma or solid tumor. They underwent intrathecal chemotherapy and bone marrow aspirations or bone marrow biopsy for diagnostic as well as therapeutic purposes. After obtaining informed consent from their parents, the research was performed. Datas were analysed by Medcalc software.Results: The total number of procedures was 810. Bone marrow aspiration was performed 402 times, bone marrow biopsy was done 30 times and intrathecal chemotherapy given 378 times. All procedures were successfully completed. The mean dose of ketamine and atropine used 1.55 ± 0.31 mg\u002Fkg and 0.100 ± 0.029 mg respectively. The recovery time was 9.2 ± 7.3 minutes. Only 0.12% experienced apnoea; 1.2% muscular hypertonicity; 4.3% nystagmus, and hyperactivity; 3.7% hypersalivation, 2.5% hallucination and 5.5% vomiting; none of the patients had laryngospasm or transient rash. All of the patients’ parents were satisfied with the use of anaesthetics. Conclusions: This is a pioneer trial for children in Vietnam. The dose of 1.5 mg\u002Fkg intravenous ketamine and 0.1mg atropine were found to be effective and suitable dose in children requiring deep sedation for painful procedures and produce only minimal side effects. We established a protocol with the above doses and continue to apply this in order to reduce pain, trauma, and complications during the procedures.","2025-07-13T20:03:48.770+00:00",[207],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F671","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F671\u002F557",[730,737,743,749,755,761,768,774],{"id":731,"sortIndex":19,"researcher":18,"roles":732,"affiliations":733,"properties":734},"f5e6cdb2-9c3f-4d8c-9151-ebe4925297ab",[],[],{"title":735},{"EN":736},"Pham Nhu Hiep",{"id":738,"sortIndex":62,"researcher":18,"roles":739,"affiliations":740,"properties":741},"0a3f1d26-4f2e-4769-b93d-979df58c5532",[],[],{"title":742},{"EN":217},{"id":744,"sortIndex":70,"researcher":18,"roles":745,"affiliations":746,"properties":747},"57346e54-7474-4c95-8c89-f250d2af4abd",[],[],{"title":748},{"EN":238},{"id":750,"sortIndex":78,"researcher":18,"roles":751,"affiliations":752,"properties":753},"caa30305-521f-4dda-b44f-417794150e21",[],[],{"title":754},{"EN":687},{"id":756,"sortIndex":86,"researcher":18,"roles":757,"affiliations":758,"properties":759},"25c06721-5b51-4e26-b135-79fa5eba2083",[],[],{"title":760},{"EN":231},{"id":762,"sortIndex":248,"researcher":18,"roles":763,"affiliations":764,"properties":765},"003a4643-f503-466b-b1bb-7f283ca6f7a9",[],[],{"title":766},{"EN":767},"Nguyen Huu Son",{"id":769,"sortIndex":256,"researcher":18,"roles":770,"affiliations":771,"properties":772},"e203667c-90d3-48cd-97ee-c176a02e2dd2",[],[],{"title":773},{"EN":694},{"id":775,"sortIndex":477,"researcher":18,"roles":776,"affiliations":777,"properties":778},"0b3b720e-0f25-41cc-b6d8-f3a0a87e5086",[],[],{"title":779},{"EN":780},"Bui Ngoc  Lan",{"url":18,"publisher":782,"properties":790},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":783,"slug":10,"properties":784,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":787,"manageAffiliations":788,"indexDatabases":789,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":785,"title":786},{"VOID":13},{"VOID":15},[],[],[],{"issue":791,"pages":793},{"VOID":792},"56",{"VOID":794},"3-7",{"total":19,"publishYear":796,"statisticByYear":797},2019,{},"2019-01-01",[],[801,803,805,807,809,811,813,815,817,819,821,823,825,827,829],{"id":18,"text":802,"url":18,"identifiers":18},"Kidd, L.R., Lyons, S.C., and Lloyd, G. (2016) Paediatric procedural sedation using ketamine in a UK emergency department: a 7 year review",{"id":18,"text":804,"url":18,"identifiers":18},"of practice. Br J Anaesth, 116, 518-23.",{"id":18,"text":806,"url":18,"identifiers":18},"Ng, K.C. Ang, S.Y. (2002) Sedation with ketamine for paediatric procedures in the emergency department-a review of 500 cases. Singapore Med J, 43, 300-4.",{"id":18,"text":808,"url":18,"identifiers":18},"Heinz, P., Geelhoed, G.C., Wee, C., and Pascoe, E.M. (2006) Is atropine needed with ketamine sedation? A prospective, randomised, double",{"id":18,"text":810,"url":18,"identifiers":18},"blind study. Emerg Med J, 23, 206-9.",{"id":18,"text":812,"url":18,"identifiers":18},"Traivaree, C., Jindakam, W., Monsereenusorn, C., Rujkijyanont, P., and Lumkul, R. (2014) The factors of ketamine that affect sedation in children with oncology procedures: parent satisfaction perspective. J Med Assoc Thai, 97 Suppl 2, S19-24.",{"id":18,"text":814,"url":18,"identifiers":18},"Heilbrunn, B.R., Chang, T.P., and Liu, D.R. (2015) A retrospective comparison of ketamine dosing regimens for pediatric procedural sedation. Eur J Emerg Med, 22, 111-6.",{"id":18,"text":816,"url":18,"identifiers":18},"Evans, D., Turnham, L., Barbour, K., Kobe, J., Wilson, L., Vandebeek, C. (2005) Intravenous ketamine sedation for painful oncology procedures. Paediatr Anaesth, 15, 131-8.",{"id":18,"text":818,"url":18,"identifiers":18},"Mason, K.P., Padua, H., Fontaine, P.J., and Zurakowski, D. (2009) Radiologist-supervised ketamine sedation for solid organ biopsies in children and adolescents. AJR Am J Roentgenol, 192, 1261-5.",{"id":18,"text":820,"url":18,"identifiers":18},"Kye, Y.C., Rhee, J.E., Kim, K., Kim, T., Jo, Y.H., Jeong, J.H. (2012) Clinical effects of adjunctive atropine during ketamine sedation in pediatric emergency patients. Am J Emerg Med, 30, 1981-5.",{"id":18,"text":822,"url":18,"identifiers":18},"Slonim, A.D. Ognibene, F.P. (1998) Sedation for pediatric procedures, using ketamine and midazolam, in a primarily adult intensive care unit: a retrospective evaluation. Crit Care Med, 26, 1900-4.",{"id":18,"text":824,"url":18,"identifiers":18},"Brown, L., Christian-Kopp, S., Sherwin, T.S., Khan, A., Barcega, B., Denmark, T.K. (2008) Adjunctive atropine is unnecessary during",{"id":18,"text":826,"url":18,"identifiers":18},"ketamine sedation in children. Acad Emerg Med, 15, 314-8.",{"id":18,"text":828,"url":18,"identifiers":18},"Patterson, A.C., Wadia, S.A., Lorenz, D.J., and Stevenson, M.D. (2017) Changes in blood pressure and heart rate during sedation with ketamine in the pediatric ED. Am J Emerg Med, 35, 322-325.",{"id":18,"text":830,"url":18,"identifiers":18},"Shi, J., Li, A., Wei, Z., Liu, Y., Xing, C., Shi, H. (2018) Ketamine versus ketamine pluses atropine for pediatric sedation: A meta-analysis. Am J Emerg Med, 36, 1280-1286.",{"id":832,"createTime":833,"updateTime":833,"relativeEntities":834,"slug":835,"properties":836,"entityType":45,"verifyStatus":17,"verifyTime":833,"verifyNote":47,"languages":845,"translateLanguages":18,"viewCount":19,"primaryUrl":846,"fullTextUrl":847,"authors":848,"publicationType":92,"publisherRelationship":895,"citationCount":19,"citationInfo":909,"publishDate":912,"publishYear":910,"citationAnalyzeStatus":354,"lastCitationAnalyze":833,"indexDatabases":913,"openAccess":18,"references":914,"isForceReanalyzing":133},"cc5ef0c2-f6e7-45b0-8bbb-9a7c8ba02f15","2025-07-13T19:52:42.779+00:00",[],"Ganglioneuroma-of-mediastinum-and-adrenal-glanda-case-report",{"abstract":837,"title":839,"gsPaper":841,"doi":843},{"EN":838},"Introduction: Ganglioneuroma is a rare benign nervous tumor arising from sympathetic ganglion which commonly occurs at posterior mediastinum, retroperitoneum and adrenal gland.Case: We report a 6 year-old boy who presented with abdomial pain. Compute tomography scan and magnetic resonance imaging (MRI) showed one tumor at his right posterior mediastinum area measuring 8.3x6.3x5.3cm, and the other tumor at his right adrenal gland measuring 3.9x3.4x3.2 cm. A biopsy showed ganglioneuroma, and complete resection of both tumors. Post operation biopsy confirm definitive diagnosis as ganglioneuroma. The patient is healthy from surgery.Conclusion: Ganglioneuroma is benign. The treatment is complete surgical resection. Prognosis after surgical resection seems to be so good, without any recurrences or need for adjuvant therapy.",{"EN":840},"Ganglioneuroma of mediastinum and adrenal glanda case report",{"VOID":842},"[\"14276970087794383936\"]",{"VOID":844},"10.38103\u002Fjcmhch.2020.64.13",[207],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F2122","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F2122\u002F1849",[849,855,862,868,875,881,888],{"id":850,"sortIndex":19,"researcher":18,"roles":851,"affiliations":852,"properties":853},"bded5590-a476-4a58-8181-b5a9c16373dc",[],[],{"title":854},{"EN":238},{"id":856,"sortIndex":62,"researcher":18,"roles":857,"affiliations":858,"properties":859},"1cb3a491-c95a-4f56-84cf-5920c5df20d7",[],[],{"title":860},{"EN":861},"Bui Binh Bao Son",{"id":863,"sortIndex":70,"researcher":18,"roles":864,"affiliations":865,"properties":866},"0593146d-442f-4957-ab82-314f0f730e6b",[],[],{"title":867},{"EN":217},{"id":869,"sortIndex":78,"researcher":18,"roles":870,"affiliations":871,"properties":872},"90c98322-0e73-46ca-b336-afdbdb822d69",[],[],{"title":873},{"EN":874},"Phan Anh Vu",{"id":876,"sortIndex":86,"researcher":18,"roles":877,"affiliations":878,"properties":879},"702e4a7c-006b-456d-84aa-2fff1bbf00ea",[],[],{"title":880},{"EN":231},{"id":882,"sortIndex":248,"researcher":18,"roles":883,"affiliations":884,"properties":885},"d9424645-eaf3-4c0f-af4b-92f22783b5c5",[],[],{"title":886},{"EN":887},"Pham Nguyen Cuong",{"id":889,"sortIndex":256,"researcher":18,"roles":890,"affiliations":891,"properties":892},"9f598ff5-4fb4-4dec-84e7-4ccbb59aa386",[],[],{"title":893},{"EN":894},"Carlos Rodriguez-Galindo",{"url":18,"publisher":896,"properties":904},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":897,"slug":10,"properties":898,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":901,"manageAffiliations":902,"indexDatabases":903,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":899,"title":900},{"VOID":13},{"VOID":15},[],[],[],{"issue":905,"pages":907},{"VOID":906},"64",{"VOID":908},"87-91",{"total":19,"publishYear":910,"statisticByYear":911},2020,{},"2020-01-01",[],[915,917,919,921,923,925,927,929,931,933,935,937],{"id":18,"text":916,"url":18,"identifiers":18},"Sawaryn T. [Ganglioneuroma of the mediastinum]. Pol Tyg Lek (Wars) 1959;14:867-70",{"id":18,"text":918,"url":18,"identifiers":18},"Hayat J, Ahmed R, Alizai S, Awan MU. Giant ganglioneuroma of the posterior mediastinum. Interact Cardiovasc Thorac Surg 2011;13:344-5",{"id":18,"text":920,"url":18,"identifiers":18},"Kiflu W, Negussie T. Ganglioneuroma of the Neck: A case report. Ethiop Med J 2017;55:69-71",{"id":18,"text":922,"url":18,"identifiers":18},"Geoerger B, Hero B, Harms D, Grebe J, Scheidhauer K, Berthold F. Metabolic activity and clinical features of primary ganglioneuromas. Cancer 2001;91:1905-13",{"id":18,"text":924,"url":18,"identifiers":18},"Lin PC, Lin SH, Chou SH, Chen YW, Chang TT, Wu JR, et al. Ganglioneuroma of posterior mediastinum in a 6-year-old girl: imaging for pediatric intrathoracic incidentaloma. Kaohsiung J Med Sci 2010;26:496-501",{"id":18,"text":926,"url":18,"identifiers":18},"Sucandy I, Akmal YM, Sheldon DG. Ganglioneuroma of the adrenal gland and retroperitoneum: A case report. N Am J Med Sci 2011;3:336-8",{"id":18,"text":928,"url":18,"identifiers":18},"Mylonas KS, Schizas D, Economopoulos KP. Adrenal ganglioneuroma: What you need to know. World J Clin Cases 2017;5:373-377",{"id":18,"text":930,"url":18,"identifiers":18},"Yorita K, Yonei A, Ayabe T, Nakada H, Nakashima K, Fukushima T, et al. Posterior mediastinal ganglioneuroma with peripheral replacement by white and brown adipocytes resulting in diagnostic fallacy from a false-positive 18F-2-fluoro-2-deoxyglucose-positron emission tomography finding: a case report. J Med Case Rep 2014;8:345",{"id":18,"text":932,"url":18,"identifiers":18},"Chang CY, Hsieh YL, Hung GY, Pan CC, Hwang B. Ganglioneuroma presenting as an asymptomatic huge posterior mediastinal and retroperitoneal tumor. J Chin Med Assoc 2003;66:370-4",{"id":18,"text":934,"url":18,"identifiers":18},"Radin R, David CL, Goldfarb H, Francis IR. Adrenal and extra-adrenal retroperitoneal ganglioneuroma: imaging findings in 13 adults. Radiology 1997;202:703-7",{"id":18,"text":936,"url":18,"identifiers":18},"Guan YB, Zhang WD, Zeng QS, Chen GQ, He JX. CT and MRI findings of thoracic ganglioneuroma. Br J Radiol 2012;85:e365-72",{"id":18,"text":938,"url":18,"identifiers":18},"Kizildag B, Alar T, Karatag O, Kosar S, Akman T, Cosar M. A case of posterior mediastinal ganglioneuroma: the importance of preoperative multiplanar radiological imaging. Balkan Med J 2013;30:126-8",{"id":940,"createTime":941,"updateTime":941,"relativeEntities":942,"slug":943,"properties":944,"entityType":45,"verifyStatus":17,"verifyTime":953,"verifyNote":47,"languages":954,"translateLanguages":18,"viewCount":19,"primaryUrl":955,"fullTextUrl":956,"authors":957,"publicationType":92,"publisherRelationship":1003,"citationCount":19,"citationInfo":1016,"publishDate":912,"publishYear":910,"citationAnalyzeStatus":354,"lastCitationAnalyze":953,"indexDatabases":1018,"openAccess":18,"references":1019,"isForceReanalyzing":133},"9ef031fe-7c10-4cc7-bb07-4e29061c6393","2025-07-13T19:49:49.851+00:00",[],"-Study-on-clinical-laboratory-features-and-the-result-of-minimal-residual-disease-after-induction-phase-in-childhood-acute-lymphoblastic-leukemia-at-Hue-Central-Hospital-in-Vietnam",{"abstract":945,"title":947,"gsPaper":949,"doi":951},{"EN":946},"Background: Acute lymphoblastic leukemia (ALL) is the most common malignant disease in children. Mininal residual disease (MRD) levels after induction phase predict outcome and may select patients for therapy intensification.Objective: To analyse clinical presentations, laboratory features, especially the result of minimal levels in childhood acute lymphoblastic leukemia patientsMethods: It was a prospective study on chilhood acute lymphoblastic leukemia patients who admitted hospital since April, 2018 to May, 2020.Results: There were 38 new patients, in which, 68.4% patients with standard risk, and 31.6% patients with high risk; the ratio of male to female was 2.16:1. The median age was 4.0 years (range: 0.66 to 15). The percentage of B-ALL, T-ALL and combined B and T- ALL were 81.6%, 15.8% and 2.6% respectively. The most common symptoms were anemia (86.8%), fever (76.3%), hepatomegaly (68.4%), splenomegaly (60.5%), enlarged lymph nodes (55.3%). For laboratory features, 26.4% patients had white blood cell (WBC) ≥ 50x109\u002Fl, 76.3% patients had platelet (PLT) < 100x109\u002Fl, 84.6% patients had blood hemoglobin level (Hb) < 10 g\u002Fdl. Lactate dehydrogenase (LDH) and C- reative protein (CRP) increased in most of patients, accounted for 89.5% and 73.7% respectively. After induction, complete remission which based on less than 5% blasts achieved 97.4%. However, MRD after induction phase with threshold ≤ 0.01% accounted for 78.9%. And based on MRD, we adjusted intensive chemotherapy for 4 patients.Conclusion: The most common clinical presentation was anemia, fever, hepatosplenomegaly, bone pain, bleeding. The result of MRD levels is more sensitive and precise to evaluate the responde after induction phase. Therefore, we could adjust intensitive therapy for some patients with high MRD levels to improve the treatment outcome.",{"EN":948}," Study on clinical, laboratory features and the result of minimal residual disease after induction phase in childhood acute lymphoblastic leukemia at Hue Central Hospital in Vietnam",{"VOID":950},"[\"15927677226743405960\"]",{"VOID":952},"10.38103\u002Fjcmhch.2020.64.3","2025-07-13T19:49:49.850+00:00",[207],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F2120","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F2120\u002F1847",[958,964,971,977,983,990,997],{"id":959,"sortIndex":19,"researcher":18,"roles":960,"affiliations":961,"properties":962},"35f1b3bf-e636-4abc-b1fc-b37446da5f05",[],[],{"title":963},{"EN":238},{"id":965,"sortIndex":62,"researcher":18,"roles":966,"affiliations":967,"properties":968},"9759ba4d-8624-415a-9c59-5db86914ffe8",[],[],{"title":969},{"EN":970},"Phan Hung Viet",{"id":972,"sortIndex":70,"researcher":18,"roles":973,"affiliations":974,"properties":975},"d16fee15-c8b2-4916-8a39-49486077aa71",[],[],{"title":976},{"EN":217},{"id":978,"sortIndex":78,"researcher":18,"roles":979,"affiliations":980,"properties":981},"7052e82e-89f5-44b8-aa67-00fb2ae3b9c6",[],[],{"title":982},{"EN":861},{"id":984,"sortIndex":86,"researcher":18,"roles":985,"affiliations":986,"properties":987},"29747bd1-6a1a-42d9-b924-017ed347ec4d",[],[],{"title":988},{"EN":989},"Bui Thi Thu Thanh",{"id":991,"sortIndex":248,"researcher":18,"roles":992,"affiliations":993,"properties":994},"d1616bcc-f390-4f53-8410-420761007bae",[],[],{"title":995},{"EN":996},"Phan Thi Thuy Hoa",{"id":998,"sortIndex":256,"researcher":18,"roles":999,"affiliations":1000,"properties":1001},"ddeae8c7-13e2-4197-890f-295139f50212",[],[],{"title":1002},{"EN":687},{"url":18,"publisher":1004,"properties":1012},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1005,"slug":10,"properties":1006,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1009,"manageAffiliations":1010,"indexDatabases":1011,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":1007,"title":1008},{"VOID":13},{"VOID":15},[],[],[],{"issue":1013,"pages":1014},{"VOID":906},{"VOID":1015},"26-32",{"total":19,"publishYear":910,"statisticByYear":1017},{},[],[1020,1022,1024,1026,1028,1030,1032,1034,1036,1038,1040],{"id":18,"text":1021,"url":18,"identifiers":18},"Fadoo Z, Nisar I, Yousuf F, Lakhani LS, Ashraf S, Imam U, et al. Clinical features and induction outcome of childhood acute lymphoblastic leukemia in a lower\u002Fmiddle income population: A multi-institutional report from Pakistan. Pediatr Blood Cancer 2015;62:1700-8",{"id":18,"text":1023,"url":18,"identifiers":18},"Uckun FM, Gaynon PS, Sensel MG, Nachman J, Trigg ME, Steinherz PG, et al. Clinical features and treatment outcome of childhood T-lineage acute lymphoblastic leukemia according to the apparent maturational stage of T-lineage leukemic blasts: a Children’s Cancer Group study. J Clin Oncol 1997;15:2214-21",{"id":18,"text":1025,"url":18,"identifiers":18},"Gaynon PS, Desai AA, Bostrom BC, Hutchinson RJ, Lange BJ, Nachman JB, et al. Early response to therapy and outcome in childhood acute lymphoblastic leukemia: a review. Cancer 1997;80:1717-26",{"id":18,"text":1027,"url":18,"identifiers":18},"Ravindranath Y. Biology of childhood acute lymphoblastic leukemia (ALL) in low\u002Fmiddle-income countries--A case for using age at diagnosis for defining low-risk all. Pediatr Blood Cancer 2015;62:1687-8",{"id":18,"text":1029,"url":18,"identifiers":18},"Howard SC, Pedrosa M, Lins M, Pedrosa A, Pui CH, Ribeiro RC, et al. Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004;291:2471-5",{"id":18,"text":1031,"url":18,"identifiers":18},"Al-Sudairy R, Al-Nasser A, Alsultan A, Al Ahmari A, Abosoudah I, Al-Hayek R, et al. Clinical characteristics and treatment outcome of childhood acute lymphoblastic leukemia in Saudi Arabia: a multi-institutional retrospective national collaborative study. Pediatr Blood Cancer 2014;61:74-80",{"id":18,"text":1033,"url":18,"identifiers":18},"Yasmeen N, Ashraf S. Childhood acute lymphoblastic leukaemia; epidemiology and clinicopathological features. J Pak Med Assoc 2009;59:150-3",{"id":18,"text":1035,"url":18,"identifiers":18},"Greaves MF, Colman SM, Beard ME, Bradstock K, Cabrera ME, Chen PM, et al. Geographical distribution of acute lymphoblastic leukaemia subtypes: second report of the collaborative group study. Leukemia 1993;7:27-34",{"id":18,"text":1037,"url":18,"identifiers":18},"Campana D, Pui CH. Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance. Blood 1995;85:1416-34",{"id":18,"text":1039,"url":18,"identifiers":18},"Vora A, Goulden N, Mitchell C, Hancock J, Hough R, Rowntree C, et al. Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial. Lancet Oncol 2014;15:809-18",{"id":18,"text":1041,"url":18,"identifiers":18},"Yeoh AE, Ariffin H, Chai EL, Kwok CS, Chan YH, Ponnudurai K, et al. Minimal residual disease-guided treatment deintensification for children with acute lymphoblastic leukemia: results from the Malaysia-Singapore acute lymphoblastic leukemia 2003 study. J Clin Oncol 2012;30:2384-92",{"id":1043,"createTime":1044,"updateTime":1044,"relativeEntities":1045,"slug":1046,"properties":1047,"entityType":45,"verifyStatus":17,"verifyTime":1054,"verifyNote":47,"languages":1055,"translateLanguages":18,"viewCount":19,"primaryUrl":1056,"fullTextUrl":1057,"authors":1058,"publicationType":92,"publisherRelationship":1111,"citationCount":19,"citationInfo":1124,"publishDate":798,"publishYear":796,"citationAnalyzeStatus":354,"lastCitationAnalyze":1054,"indexDatabases":1126,"openAccess":18,"references":1127,"isForceReanalyzing":133},"9c02af12-5a79-4799-85af-8176389d7428","2025-07-13T16:17:43.194+00:00",[],"Long-term-outcome-of-childhood-acute-myeloid-leukemia-at-Hue-central-hospital",{"title":1048,"gsPaper":1050,"abstract":1052},{"EN":1049},"Long-term outcome of childhood acute myeloid leukemia at Hue central hospital",{"VOID":1051},"[\"229575091648168796\"]",{"EN":1053},"ABSTRACTBackground: Hue Central Hospital (HCH) plays a key role intreating Acute Myeloid Leukemia (AML) in the central zone of Vietnam which covers geographically vast areas. Before 2010, all the AML patients died, and abandonment rate was more than 50%. The aims of this study are to determine the outcome of newly diagnosed children with AML treated at HCH from 2010 to 2018.Methods: This is a retrospective review of 98 children with AML admitted from January 2010 to December 2018. The diagnosis was confirmed by morphological FAB criteria, cytochemistry and immunophenotype. Patients were treated with using modified AML 7-3 Regimen. Social supports were provided to patients\u002Ffamilies.Results: A total of 98 children with AML were analyzed with median age of 5,6 years ranging from 3 months to 15 years. The male to female ratio was 1,8:1. The overall complete remission (CR) rate on day 21 of induction were 62.2%. 46 patients (46.9%) appeared relapse, in which 27 patients had relapse during the time they recured chemotherapy, 19.4% after finishing chemotherapy. Overall survival (OS) at 8 years were 23.2%. The event-free survival (EFS) at 8 years were 20.2%. Abandonment cases were 4 (4.1%).Conclusion: With less toxic modified protocol, survival rate has been improved and treatment related mortality was minimized though high relapse rate is still an issue. Abandonment has been reduced successfully with holistic strategies such as financial support, managing family group, providing education, early follow-up of patients who missed appointments and free accommodation near hospital for patients\u002Ffamilies.","2025-07-13T16:17:43.193+00:00",[207],"https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fview\u002F708","https:\u002F\u002Fjcmhch.com.vn\u002Findex.php\u002Fhome\u002Farticle\u002Fdownload\u002F708\u002F589",[1059,1065,1071,1078,1085,1091,1097,1104],{"id":1060,"sortIndex":19,"researcher":18,"roles":1061,"affiliations":1062,"properties":1063},"645307f2-1e09-4cbb-a051-6935cb7972ff",[],[],{"title":1064},{"EN":687},{"id":1066,"sortIndex":62,"researcher":18,"roles":1067,"affiliations":1068,"properties":1069},"759ffa9d-0ae1-4499-bb64-61d252c75007",[],[],{"title":1070},{"EN":217},{"id":1072,"sortIndex":70,"researcher":18,"roles":1073,"affiliations":1074,"properties":1075},"48078e1b-70a5-4b6a-b567-579fa7b42bdb",[],[],{"title":1076},{"EN":1077},"Phan Xuan Mai",{"id":1079,"sortIndex":78,"researcher":18,"roles":1080,"affiliations":1081,"properties":1082},"cb297292-69ec-4ee2-ad08-18343dfb42cc",[],[],{"title":1083},{"EN":1084},"Phan Huy Thuan",{"id":1086,"sortIndex":86,"researcher":18,"roles":1087,"affiliations":1088,"properties":1089},"22fc543e-349f-4f1d-9258-be729fceaf85",[],[],{"title":1090},{"EN":238},{"id":1092,"sortIndex":248,"researcher":18,"roles":1093,"affiliations":1094,"properties":1095},"4ae70b35-c566-4b5c-bd22-f18a0aabc446",[],[],{"title":1096},{"EN":767},{"id":1098,"sortIndex":256,"researcher":18,"roles":1099,"affiliations":1100,"properties":1101},"16eecba1-a24e-4093-990a-0d4e264337bf",[],[],{"title":1102},{"EN":1103},"Truong Thi Kim Yen",{"id":1105,"sortIndex":477,"researcher":18,"roles":1106,"affiliations":1107,"properties":1108},"a6ab1c21-c2e3-4638-ba6d-a54809e31c61",[],[],{"title":1109},{"EN":1110},"Watanabe Kazuyo",{"url":18,"publisher":1112,"properties":1120},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1113,"slug":10,"properties":1114,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":1117,"manageAffiliations":1118,"indexDatabases":1119,"url":23,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":24,"analyzePriority":18},[],{"issn":1115,"title":1116},{"VOID":13},{"VOID":15},[],[],[],{"issue":1121,"pages":1122},{"VOID":792},{"VOID":1123},"46-51",{"total":19,"publishYear":796,"statisticByYear":1125},{},[],[1128,1130,1132,1134,1136,1138,1140,1142,1144,1146,1148,1150,1152,1154,1156,1158,1160,1162,1164,1166,1168,1170,1172,1174],{"id":18,"text":1129,"url":18,"identifiers":18},"Gamis AS, Alonzo TA, Perentesis JP, Meshinchi S, Committee COGAML (2013) Children’s Oncology Group’s 2013 blueprint for research: acute myeloid leukemia. 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The Medical Research Council Adult and Children’s Leukaemia Working Parties. Blood 92: 2322-33.",{"id":18,"text":1141,"url":18,"identifiers":18},"Ter Bals E, Kaspers GJ (2005) Treatment of childhood acute myeloid leukemia. Expert Rev Anticancer Ther 5: 917-29.",{"id":18,"text":1143,"url":18,"identifiers":18},"Ward E, DeSantis C, Robbins A, Kohler B, Jemal A (2014) Childhood and adolescent cancer statistics, 2014. CA Cancer J Clin 64: 83-103.",{"id":18,"text":1145,"url":18,"identifiers":18},"Viana MB, Cunha KC, Ramos G, Murao M (2003) [Acute myeloid leukemia in childhood: 15-year experience in a single institution]. J Pediatr (Rio J) 79: 489-96.",{"id":18,"text":1147,"url":18,"identifiers":18},"Imamura T, Iwamoto S, Kanai R, Shimada A, Terui K, el al (2012) Outcome in 146 patients with paediatric acute myeloid leukaemia treated according to the AML99 protocol in the period 2003-06 from the Japan Association of Childhood Leukaemia Study. Br J Haematol 159: 204-10.",{"id":18,"text":1149,"url":18,"identifiers":18},"Creutzig U, van den Heuvel-Eibrink MM, Gibson B, Dworzak MN, Adachi S, el al (2012) Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel. Blood 120: 3187-205.",{"id":18,"text":1151,"url":18,"identifiers":18},"Creutzig U, Zimmermann M, Ritter J, Reinhardt D, Hermann J, el al (2005) Treatment strategies and long-term results in paediatric patients",{"id":18,"text":1153,"url":18,"identifiers":18},"treated in four consecutive AML-BFM trials. Leukemia 19: 2030-42.",{"id":18,"text":1155,"url":18,"identifiers":18},"Sandahl JD, Kjeldsen E, Abrahamsson J, Ha SY, Heldrup J, el al (2014) Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study. 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