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Phys Chem Chem Phys C 14:4844–4858\nZahrae M, Monshi A, Puerto Morales M, Shahbazi-Gahrouei D, Amirnasr M, Behdadfar B (2015) Hydrothermal synthesis of fine stabilized superparamagnetic nanoparticles of Zn2+ substituted manganese ferrite. J Magn Magn Mater 393:429–436\nZhang X, Chen Z, Liu J, Cui S (2021) Synthesis and characterization of Fe3O4 nanoparticles on infrared radiation by xerogel with sol-gel method. Chem Phys Lett 764:138265–138270",{"EN":136},"Recent innovations in nanotechnology have opened the applicability of multifunctional nanoparticles (NPs) in biomedical diagnosis and treatment. The examples of NPs which have attracted considerable attention in recent years are metals (e.g., Au, Ag, Mg), alloys (e.g., Fe–Co, Fe–Pd, Fe–Pt, Co–Pt), iron oxides (e.g., Fe2O3 and Fe3O4), substituted ferrites (e.g., MnFe2O4 and CoFe2O4), manganites (e.g., \n                \n                  \n                \n                $${\\mathrm{La}}_{0.67}{\\mathrm{Sr}}_{0.33}{\\mathrm{MnO}}_{3}$$\n                \n              ), etc. Special attention has been paid to magnetic NPs (MNPs), as they are the potential candidates for several biomedical appliances, such as hyperthermia applications, magnetic resonance imaging, contrast imaging, and drug delivery. To achieve effective MNPs, a thorough investigation on the synthesis, and characteristic properties, including size, magnetic properties, and toxicity, is required. Furthermore, the surfaces of the NPs must be tailored to improve the biocompatibility properties and reduce agglomeration. The present review focuses on different mechanisms to develop biocompatible MNPs. The utility of these MNPs in various biomedical applications, especially in treating and diagnosing human diseases, such as targeted drug delivery, hyperthermia treatment for cancer, and other biomedical diagnoses, is thoroughly discussed in this article. Different synthetic processes and important physical properties of these MNPs and their biocomposites are presented.",{"EN":138},"Synthesis, physical properties, and biomedical applications of magnetic nanoparticles: a review",{"VOID":140},"10.1007\u002Fs40204-022-00204-8","PUBLICATION","VERIFIED","Auto Verify",1,"https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-022-00204-8",[147,163],{"id":148,"sortIndex":23,"researcher":22,"roles":149,"affiliations":151,"properties":160},"a7a8bff6-3cdd-4d10-b9ae-ac1e648eef96",[150],"AUTHOR",[152],{"id":22,"sortIndex":23,"affiliation":153,"properties":22},{"id":154,"createTime":155,"updateTime":155,"relativeEntities":156,"slug":22,"properties":157,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"8bdd6484-8dff-4c12-9dce-1228ae7b12d4","2024-01-14T02:43:38.874+00:00",[],{"title":158},{"VI":159},"Department of Physics, Birla Institute of Technology, Mesra, Ranchi, India",{"title":161},{"VI":162},"Sunita Keshri",{"id":164,"sortIndex":144,"researcher":22,"roles":165,"affiliations":166,"properties":175},"9f9fa642-7cf5-4218-b503-190c3b58c62e",[150],[167],{"id":22,"sortIndex":23,"affiliation":168,"properties":22},{"id":169,"createTime":170,"updateTime":170,"relativeEntities":171,"slug":22,"properties":172,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"d3207d34-3ce2-42a9-92d1-6416cce30b7c","2023-12-04T17:10:53.092+00:00",[],{"title":173},{"VI":174},"Department of Engineering Physics, College of Engineering, Koneru Lakshmaiah Education Foundation, Vaddeswaram, India",{"title":176},{"VI":177},"Sonali Biswas","ARTICLE",{"url":145,"publisher":180,"properties":209},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":181,"slug":10,"properties":182,"entityType":20,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"subjectFields":187,"manageAffiliations":188,"indexDatabases":189,"url":22,"thumbnailPath":22,"statistic":204,"gsStatistic":22,"type":121,"analyzePriority":22},[],{"issn":183,"eissn":184,"title":185,"url":186},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},[],[],[190,197],{"id":88,"indexDatabase":191,"url":101,"indexYears":102,"academicFieldIds":196,"indexDatabaseRanking":106},{"id":90,"createTime":91,"updateTime":92,"relativeEntities":192,"label":193,"description":194,"key":98,"publicationTags":195,"standard":22},[],{"EN":95,"VI":95},{"EN":95,"VI":97},[100],[104,105],{"id":68,"indexDatabase":198,"url":83,"indexYears":22,"academicFieldIds":203,"indexDatabaseRanking":22},{"id":70,"createTime":71,"updateTime":72,"relativeEntities":199,"label":200,"description":201,"key":79,"publicationTags":202,"standard":22},[],{"EN":75,"VI":75},{"VI":77,"EN":78},[81,82],[85,86],{"impactFactor":23,"impactFactorByYear":205,"i10Index":23,"i10IndexLast5Year":23,"totalPublication":109,"totalPublicationByYear":206,"totalCitation":23,"totalCitationByYear":207,"totalCitationPerPublication":23,"totalCitationPerPublicationByYear":208,"hindexLast5Year":23,"hindex":23},{},{"2012":111,"2013":112,"2014":52,"2015":113,"2016":114,"2017":115,"2018":64,"2019":116,"2020":115,"2021":117,"2022":118,"2023":111},{},{},{"volume":210,"pages":212},{"VOID":211},"11",{"VOID":213},"347-372","2022-09-26",2022,false,{"id":218,"createTime":219,"updateTime":219,"relativeEntities":220,"slug":22,"properties":221,"entityType":141,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"primaryUrl":230,"fullTextUrl":22,"authors":231,"publicationType":178,"publisherRelationship":296,"citationCount":22,"citationInfo":22,"publishDate":331,"publishYear":332,"citationAnalyzeStatus":21,"lastCitationAnalyze":22,"indexDatabases":22,"openAccess":22,"references":22,"isForceReanalyzing":216},"214502e7-424e-4966-bd57-f3c26ad01cd2","2024-01-10T23:56:38.074+00:00",[],{"references":222,"abstract":224,"title":226,"doi":228},{"VOID":223},"Abedalwafa M, Wang F, Wang L, Li C (2013) Biodegradable poly-ε-caprolactone (PCL) for tissue engineering applications: a review. 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J Med Biol Eng 33:171–178. https:\u002F\u002Fdoi.org\u002F10.5405\u002Fjmbe.1072\nYao Q, Cosme JGL, Xu T, Miszuk JM, Picciani PHS, Fong H, Sun H (2017) Three dimensional electrospun PCL\u002FPLA blend nanofibrous scaffolds with significantly improved stem cells osteogenic differentiation and cranial bone formation. Biomaterials 115:115–127. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.biomaterials.2016.11.018\nYarin AL (2011) Coaxial electrospinning and emulsion electrospinning of core-shell fibers. Polym Adv Technol 22:310–317. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fpat.1781\nZadehnajar P, Akbari B, Karbasi S, Mirmusavi MH (2020a) Preparation and characterization of poly ε-caprolactone-gelatin\u002Fmulti-walled carbon nanotubes electrospun scaffolds for cartilage tissue engineering applications. Int J Polym Mater Polym Biomater 69:326–337. https:\u002F\u002Fdoi.org\u002F10.1080\u002F00914037.2018.1563088\nZadehnajar P, Karbasi S, Akbari B, Ghasemi L (2020b) Incorporation of multi-walled carbon nanotubes into electrospun PCL\u002Fgelatin scaffold: The influence on the physical, chemical and thermal properties and cell response for tissue engineering. Mater Technol 35:39–49. https:\u002F\u002Fdoi.org\u002F10.1080\u002F10667857.2019.1651539\nZahedi E, Esmaeili A, Eslahi N, Shokrgozar MA, Simchi A (2019) Fabrication and characterization of core-shell electrospun fibrous mats containing medicinal herbs for wound healing and skin tissue engineering. Mar Drugs 17:1–13. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fmd17010027\nZarekhalili Z, Bahrami SH, Ranjbar-Mohammadi M, Milan PB (2017) Fabrication and characterization of PVA\u002FGum tragacanth\u002FPCL hybrid nanofibrous scaffolds for skin substitutes. Int J Biol Macromol 94:679–690. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.ijbiomac.2016.10.042",{"EN":225},"The restoration of normal functioning of damaged body tissues is one of the major objectives of tissue engineering. Scaffolds are generally used as artificial supports and as substrates for regenerating new tissues and should closely mimic natural extracellular matrix (ECM). The materials used for fabricating scaffolds must be biocompatible, non-cytotoxic and bioabsorbable\u002Fbiodegradable. For this application, specifically biopolymers such as PLA, PGA, PTMC, PCL etc. satisfying the above criteria are promising materials. Poly(ε-caprolactone) (PCL) is one such potential candidate which can be blended with other materials forming blends, copolymers and composites with the essential physiochemical and mechanical properties as per the requirement. Nanofibrous scaffolds are fabricated by various techniques such as template synthesis, fiber drawing, phase separation, self-assembly, electrospinning etc. Among which electrospinning is the most popular and versatile technique. It is a clean, simple, tunable and viable technique for fabrication of polymer-based nanofibrous scaffolds. The design and fabrication of electrospun nanofibrous scaffolds are of intense research interest over the recent years. These scaffolds offer a unique architecture at nano-scale with desired porosity for selective movement of small molecules and form a suitable three-dimensional matrix similar to ECM. This review focuses on PCL synthesis, modifications, properties and scaffold fabrication techniques aiming at the targeted tissue engineering applications.",{"EN":227},"Poly (ε-caprolactone)-based electrospun nano-featured substrate for tissue engineering applications: a review",{"VOID":229},"10.1007\u002Fs40204-021-00157-4","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-021-00157-4",[232,259,281],{"id":233,"sortIndex":111,"researcher":22,"roles":234,"affiliations":235,"properties":256},"abdb126e-0b26-4453-871f-2e47581bd8a4",[150],[236,244],{"id":22,"sortIndex":23,"affiliation":237,"properties":22},{"id":238,"createTime":239,"updateTime":239,"relativeEntities":240,"slug":22,"properties":241,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"9fdfdd46-99f3-4df6-9fff-6bedf5babbf5","2024-01-13T17:59:28.885+00:00",[],{"title":242},{"VI":243},"Materials Science Division, CSIR-National Aerospace Laboratories, Bangalore, India",{"id":245,"sortIndex":144,"affiliation":246,"properties":255},"e262281a-8322-497a-b66b-a893664ccebd",{"id":247,"createTime":248,"updateTime":249,"relativeEntities":250,"slug":251,"properties":252,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"18b37478-12d7-457b-99d2-9517b15dc21d","2023-12-06T12:47:26.589+00:00","2025-01-29T03:36:08.392+00:00",[],"Academy-of-Scientific-and-Innovative-Research-AcSIR-Ghaziabad-India",{"title":253},{"VI":254},"Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India",{},{"title":257},{"VI":258},"P. K. Panda",{"id":260,"sortIndex":23,"researcher":22,"roles":261,"affiliations":262,"properties":278},"e85ff4f3-a1f4-424e-9fb2-eb68f639c33c",[150],[263,270],{"id":264,"sortIndex":144,"affiliation":265,"properties":269},"763ce8e7-0e4d-466a-a648-d001407bd8e3",{"id":247,"createTime":248,"updateTime":249,"relativeEntities":266,"slug":251,"properties":267,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":268},{"VI":254},{},{"id":22,"sortIndex":23,"affiliation":271,"properties":22},{"id":272,"createTime":273,"updateTime":273,"relativeEntities":274,"slug":22,"properties":275,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"be6eb19c-867a-403e-ac45-f2481d1a26df","2024-01-10T23:56:38.087+00:00",[],{"title":276},{"VI":277},"Materials Science Division, CSIR - National Aerospace Laboratories, Bangalore, India",{"title":279},{"VI":280},"B. Sowmya",{"id":282,"sortIndex":144,"researcher":22,"roles":283,"affiliations":284,"properties":293},"af01f502-74e4-4c2c-aad8-e72aace06e7b",[150],[285],{"id":22,"sortIndex":23,"affiliation":286,"properties":22},{"id":287,"createTime":288,"updateTime":288,"relativeEntities":289,"slug":22,"properties":290,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"7dd087cd-6113-48dc-8ba8-0e90033de22c","2023-12-14T22:27:21.873+00:00",[],{"title":291},{"VI":292},"Department of Polymer Science and Technology, Sri Jayachamarajendra College of Engineering, JSS Science and Technology University, Mysuru, India",{"title":294},{"VI":295},"A. B. Hemavathi",{"url":230,"publisher":297,"properties":326},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":298,"slug":10,"properties":299,"entityType":20,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"subjectFields":304,"manageAffiliations":305,"indexDatabases":306,"url":22,"thumbnailPath":22,"statistic":321,"gsStatistic":22,"type":121,"analyzePriority":22},[],{"issn":300,"eissn":301,"title":302,"url":303},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},[],[],[307,314],{"id":88,"indexDatabase":308,"url":101,"indexYears":102,"academicFieldIds":313,"indexDatabaseRanking":106},{"id":90,"createTime":91,"updateTime":92,"relativeEntities":309,"label":310,"description":311,"key":98,"publicationTags":312,"standard":22},[],{"EN":95,"VI":95},{"EN":95,"VI":97},[100],[104,105],{"id":68,"indexDatabase":315,"url":83,"indexYears":22,"academicFieldIds":320,"indexDatabaseRanking":22},{"id":70,"createTime":71,"updateTime":72,"relativeEntities":316,"label":317,"description":318,"key":79,"publicationTags":319,"standard":22},[],{"EN":75,"VI":75},{"VI":77,"EN":78},[81,82],[85,86],{"impactFactor":23,"impactFactorByYear":322,"i10Index":23,"i10IndexLast5Year":23,"totalPublication":109,"totalPublicationByYear":323,"totalCitation":23,"totalCitationByYear":324,"totalCitationPerPublication":23,"totalCitationPerPublicationByYear":325,"hindexLast5Year":23,"hindex":23},{},{"2012":111,"2013":112,"2014":52,"2015":113,"2016":114,"2017":115,"2018":64,"2019":116,"2020":115,"2021":117,"2022":118,"2023":111},{},{},{"volume":327,"pages":329},{"VOID":328},"10",{"VOID":330},"91-117","2021-06-02",2021,{"id":334,"createTime":335,"updateTime":336,"relativeEntities":337,"slug":338,"properties":339,"entityType":141,"verifyStatus":142,"verifyTime":348,"verifyNote":143,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":144,"primaryUrl":349,"fullTextUrl":22,"authors":350,"publicationType":178,"publisherRelationship":396,"citationCount":22,"citationInfo":22,"publishDate":430,"publishYear":215,"citationAnalyzeStatus":21,"lastCitationAnalyze":22,"indexDatabases":22,"openAccess":22,"references":22,"isForceReanalyzing":216},"210f4a99-b6dd-4970-88dc-6c13ddc0174b","2024-02-14T17:57:54.929+00:00","2024-12-14T23:49:15.642+00:00",[],"An-aorta-ECM-extracted-hydrogel-as-a-biomaterial-in-vascular-tissue-engineering-application",{"references":340,"abstract":342,"title":344,"doi":346},{"VOID":341},"Badylak SF, Taylor D, Uygun K (2011) Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds. Annu Rev Biomed Eng 13:27–53\nBakhtiar H, Pezeshki-Modaress M, Kiaipour Z, Shafiee M, Ellini MR, Mazidi A, Rajabi S, Zamanlui Benisi S, Ostad SN, Galler K, Pakshir P, Azarpazhooh A, Kishen A (2020) Pulp ECM-derived macroporous scaffolds for stimulation of dental-pulp regeneration process. Dent Mater 36:76–87. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.dental.2019.10.011\nBalakumar P, Maung-U K, Jagadeesh G (2016) Prevalence and prevention of cardiovascular disease and diabetes mellitus. Pharmacol Res 113:600–609\nCatto V, Farè S, Freddi G, Tanzi MC (2014) Vascular tissue engineering: recent advances in small diameter blood vessel regeneration. ISRN Vasc Med. https:\u002F\u002Fdoi.org\u002F10.1155\u002F2014\u002F923030\nChan BP, Leong KW (2008) Scaffolding in tissue engineering: general approaches and tissue-specific considerations. Eur Spine J 17:467–479\nClaudio-Rizo JA, Delgado J, Quintero-Ortega IA, Mata-Mata JL, Mendoza-Novelo B (2018) Decellularized ECM-derived hydrogels: modification and properties. Hydrogels. https:\u002F\u002Fdoi.org\u002F10.5772\u002Fintechopen.78331\nDeQuach JA, Yuan SH, Goldstein LSB, Christman KL (2011) Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. Tissue Eng Part A 17:2583–2592\nDíaz-Zuccarini V, Lawford PV (2010) An in-silico future for the engineering of functional tissues and organs. Organogenesis 6:245–251. https:\u002F\u002Fdoi.org\u002F10.4161\u002Forg.6.4.13284\nEngel H, Kao S-W, Larson J, Uriel S, Jiang B, Brey E, Cheng M-H (2015) Investigation of Dermis-derived hydrogels for wound healing applications. Biomed J 38(1):58–64. https:\u002F\u002Fdoi.org\u002F10.4103\u002F2319-4170.132899\nFereshteh Z (2018) Freeze-drying technologies for 3D scaffold engineering. In: Deng Y, Kuiper J (eds) Functional 3D tissue engineering scaffolds. Elsevier, pp 151–174\nFreytes DO, Martin J, Velankar SS, Lee AS, Badylak SF (2008) Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix. Biomaterials 29(11):1630–1637. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.biomaterials.2007.12.014\nGothard D, Smith EL, Kanczler JM, Black CR, Wells JA, Roberts CA, White LJ, Qutachi O, Peto H, Rashidi H (2015) In vivo assessment of bone regeneration in alginate\u002Fbone ECM hydrogels with incorporated skeletal stem cells and single growth factors. PLoS One 10:e0145080\nHati S, Agrawal S, Rai V (2021) Vascular regeneration and tissue engineering: progress, clinical impact, and future challenges. In: Sharma CP (ed) Regenerated organs. Elsevier, pp 153–166\nHinderer S, Layland SL, Schenke-Layland K (2016) ECM and ECM-like materials—biomaterials for applications in regenerative medicine and cancer therapy. Adv Drug Deliv Rev 97:260–269\nJiankang H, Dichen L, Yaxiong L, Bo Y, Bingheng L, Qin L (2007) Fabrication and characterization of chitosan\u002Fgelatin porous scaffolds with predefined internal microstructures. Polymer (Guildf) 48:4578–4588. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.polymer.2007.05.048\nKhajavi M, Hajimoradloo A, Zandi M, Pezeshki-Modaress M, Bonakdar S, Zamani A (2021) Fish cartilage: A promising source of biomaterial for biological scaffold fabrication in cartilage tissue engineering. J Biomed Mater Res Part A 109:1737–1750\nKim I-H, Ko IK, Atala A, Yoo JJ (2015) Whole kidney engineering for clinical translation. Curr Opin Organ Transplant 20:165–170\nLee P-H, Tsai S-H, Kuo L, Hwang C-Y, Kuo C-Y, Yang VC, Chen J-K (2012) A prototype tissue engineered blood vessel using amniotic membrane as scaffold. Acta Biomater 8:3342–3348\nLee JS, Shin J, Park H-M, Kim Y-G, Kim B-G, Oh J-W, Cho S-W (2014) Liver extracellular matrix providing dual functions of two-dimensional substrate coating and three-dimensional injectable hydrogel platform for liver tissue engineering. Biomacromol 15:206–218\nLi S, Sengupta D, Chien S (2014) Vascular tissue engineering: from in vitro to in situ. Wiley Interdiscip Rev Syst Biol Med 6:61–76\nLin T, Liu S, Chen S, Qiu S, Rao Z, Liu J, Zhu S, Yan L, Mao H, Zhu Q, Quan D, Liu X (2018) Acta Biomaterialia Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects. Acta Biomater. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.actbio.2018.04.001\nLongo UG, Lamberti A, Maffulli N, Denaro V (2011) Tissue engineered biological augmentation for tendon healing: a systematic review. Br Med Bull 98:31–59\nMahboudi S, Pezeshki-Modaress M, Noghabi KA (2015) The study of fibroblast cell growth on the porous scaffold of gelatin-starch blend using the salt-leaching and lyophilization method. Int J Polym Mater Polym Biomater 64:653–659. https:\u002F\u002Fdoi.org\u002F10.1080\u002F00914037.2014.1002095\nMao JS, Zhao LG, Yin YJ, De Yao K (2003) Structure and properties of bilayer chitosan–gelatin scaffolds. Biomaterials 24:1067–1074\nMassaro MS, Pálek R, Rosendorf J, Červenková L, Liška V, Moulisová V (2021) Decellularized xenogeneic scaffolds in transplantation and tissue engineering: immunogenicity versus positive cell stimulation. Mater Sci Eng C 127:112203\nMassensini AR, Ghuman H, Saldin LT, Medberry CJ, Keane TJ, Nicholls FJ, Velankar SS, Badylak SF, Modo M (2015) Concentration-dependent rheological properties of ECM hydrogel for intracerebral delivery to a stroke cavity. Acta Biomater 27:116–130\nMcfetridge PS, Daniel JW, Bodamyali T, Horrocks M, Chaudhuri JB (2004) Preparation of porcine carotid arteries for vascular tissue engineering applications. J Biomedical Mater Res Part A. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fjbm.a.30060\nModaress MP, Mirzadeh H, Zandi M (2012) Fabrication of a porous wall and higher interconnectivity scaffold comprising gelatin\u002Fchitosan via combination of salt-leaching and lyophilization methods. Iran Polym J 21:191–200. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs13726-012-0019-0\nMozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, De Ferranti S, Després J-P, Fullerton HJ (2016) Executive summary: heart disease and stroke statistics—2016 update: a report from the American Heart Association. Circulation 133:447–454\nNiklason LE, Langer R (2001) Prospects for organ and tissue replacement. 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J Biomed Mater Res B Appl Biomater 108(8):3302–3310. https:\u002F\u002Fdoi.org\u002F10.1002\u002Fjbm.b.34666\nRajabi-zeleti S, Jalili-firoozinezhad S, Azarnia M, Khademhosseini A, Baharvand H, Aghdami N (2014) The behavior of cardiac progenitor cells on macroporous pericardium-derived scaffolds. Biomaterials 35:970–982. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.biomaterials.2013.10.045\nRakel BA, Bermel MA, Abbott LI, Baumler SK, Burger MR, Dawson CJ, Heinle JA, Ocheltree IM (1998) Split-thickness skin graft donor site care: a quantitative synthesis of the research. Appl Nurs Res 11:174–182\nRen T, van der Merwe Y, Steketee MB (2015) Developing extracellular matrix technology to treat retinal or optic nerve injury. ENeuro. https:\u002F\u002Fdoi.org\u002F10.1523\u002FENEURO.0077-15.2015\nSaldin LT, Cramer MC, Velankar SS, White LJ, Badylak SF (2017) Extracellular matrix hydrogels from decellularized tissues: structure and function. Acta Biomater 49:1–15. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.actbio.2016.11.068\nSawkins MJ, Bowen W, Dhadda P, Markides H, Sidney LE, Taylor AJ, Rose FRAJ, Badylak SF, Shakesheff KM, White LJ (2013) Hydrogels derived from demineralized and decellularized bone extracellular matrix. Acta Biomater 9:7865–7873. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.actbio.2013.04.029\nSchmidt CE, Baier JM (2000) Acellular vascular tissues: natural biomaterials for tissue repair and tissue engineering. Biomaterials 21(22):2215–2231. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fs0142-9612(00)00148-4\nStoppel WL, Hu D, Domian IJ, Kaplan DL, Black LD III (2015) Anisotropic silk biomaterials containing cardiac extracellular matrix for cardiac tissue engineering. Biomed Mater 10:34105\nTamimi M, Rajabi S, Pezeshki-Modaress M (2020) Cardiac ECM\u002Fchitosan\u002Falginate ternary scaffolds for cardiac tissue engineering application. 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Acta Biomater 16:49–59",{"EN":343},"Biological scaffolds have been undergoing significant growth in tissue engineering applications over the last years. Biopolymers extracted from ECM with various protein factors and other biological agents have been active in restoring damaged tissue. In the present study, bioactive scaffold is prepared from bovine aorta extracted natural polymeric hydrogel with advantages of availability and cost-effectiveness. The biological scaffolds were prepared through freeze-drying method to make a 3D sponge with appropriate structure, well-defined architecture and interconnected pores for vascular tissue engineering, and studied the effect of aorta hydrogel concentrations (1, 2, 3, and 4% w\u002Fv) on the scaffolds. The prepared biological scaffolds were analyzed by mechanical tests, FTIR, SEM, porosity and PBS absorption. Moreover, the morphology and proliferation of human umbilical vein cord cells on the 3D sponges were investigated. Histological analysis including, Masson trichrome (MT), hematoxylin and eosin (H&E), Verhoeff\u002FVan Gieson (VVG) and alcian blue (AB) revealed that during this process the main components of aorta extracellular matrix containing collagen, elastin, and glycosaminoglycan were well preserved. The obtained results revealed that the scaffolds porosity were more than 90%. The Aorta-ECM4% enabled HUVECs to survive, proliferate and migrate better than 2% and 3% aorta-ECM. \n                  \n                    \n                      \n                    \n                  \n                ",{"EN":345},"An aorta ECM extracted hydrogel as a biomaterial in vascular tissue engineering application",{"VOID":347},"10.1007\u002Fs40204-022-00186-7","2024-12-14T23:49:15.641+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-022-00186-7",[351,366,381],{"id":352,"sortIndex":144,"researcher":22,"roles":353,"affiliations":354,"properties":363},"a89bcdd7-c435-42bd-bcd9-36e09bcbf1b6",[150],[355],{"id":22,"sortIndex":23,"affiliation":356,"properties":22},{"id":357,"createTime":358,"updateTime":358,"relativeEntities":359,"slug":22,"properties":360,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"b233a44b-bd21-4bac-b7ce-b5364db65633","2023-12-27T06:05:47.448+00:00",[],{"title":361},{"VI":362},"Burn Research Center, Iran University of Medical Sciences, Tehran, Iran",{"title":364},{"VI":365},"Mohamad 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Trends Biotechnol 22:643–652\nYeong WY, Sudarmadji N, Yu HY, Chua CK, Leong KF, Venkatraman SS, Boey YCF, Tan LP (2010) Porous polycaprolactone scaffold for cardiac tissue engineering fabricated by selective laser sintering. Acta Biomater 6:2028–2034\nYin Y, Ye F, Cui J, Zhang F, Li X, Yao K (2003) Preparation and characterization of macroporous chitosan–gelatin\u002Fβ-tricalcium phosphate composite scaffolds for bone tissue engineering. J Biomed Mater Res Part A 67A:844–855\nZein I, Hutmacher DW, Tan KC, Teoh SH (2002) Fused deposition modeling of novel scaffold architectures for tissue engineering applications. Biomaterials 23:1169–1185\nZhang K, Wang Y, Hillmyer MA, Francis LF (2004) Processing and properties of porous poly(L-lactide)\u002Fbioactive glass composites. Biomaterials 25:2489–2500\nZhang Y, Hao L, Savalani MM, Harris RA, Silvio LD, Tanner KE (2008) In vitro biocompatibility of hydroxyapatite-reinforced polymeric composites manufactured by selective laser sintering. J Biomed Mater Res 91A:1018–1027\nZhou Y, Hutmacher DW, Varawan S-L, Lim TM (2007a) In vitro bone engineering based on polycaprolactone and polycaprolactone–tricalcium phosphate composites. Polym Int 56:333–342\nZhou Y, Chen F, Ho ST, Woodruff MA, Lim TM, Hutmacher DW (2007b) Combined marrow stromal cell-sheet techniques and high-strength biodegradable composite scaffolds for engineered functional bone grafts. Biomaterials 28:814–824",{"EN":755},"Tissue engineering is essentially a technique for imitating nature. Natural tissues consist of three components: cells, signalling systems (e.g. growth factors) and extracellular matrix (ECM). The ECM forms a scaffold for its cells. Hence, the engineered tissue construct is an artificial scaffold populated with living cells and signalling molecules. A huge effort has been invested in bone tissue engineering, in which a highly porous scaffold plays a critical role in guiding bone and vascular tissue growth and regeneration in three dimensions. In the last two decades, numerous scaffolding techniques have been developed to fabricate highly interconnective, porous scaffolds for bone tissue engineering applications. This review provides an update on the progress of foaming technology of biomaterials, with a special attention being focused on computer-aided manufacturing (Andrade et al. 2002) techniques. This article starts with a brief introduction of tissue engineering (Bone tissue engineering and scaffolds) and scaffolding materials (Biomaterials used in bone tissue engineering). After a brief reviews on conventional scaffolding techniques (Conventional scaffolding techniques), a number of CAM techniques are reviewed in great detail. For each technique, the structure and mechanical integrity of fabricated scaffolds are discussed in detail. Finally, the advantaged and disadvantage of these techniques are compared (Comparison of scaffolding techniques) and summarised (Summary).",{"EN":757},"Bone tissue engineering scaffolding: computer-aided scaffolding techniques",{"VOID":759},"10.1007\u002Fs40204-014-0026-7","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-014-0026-7",[762,777,792,810,822],{"id":763,"sortIndex":144,"researcher":22,"roles":764,"affiliations":765,"properties":774},"5361a3e9-d9e5-40d7-857f-995cfea57f62",[150],[766],{"id":22,"sortIndex":23,"affiliation":767,"properties":22},{"id":768,"createTime":769,"updateTime":769,"relativeEntities":770,"slug":22,"properties":771,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"d4589415-e640-4ca1-ad18-566ee99210fc","2024-01-08T23:25:04.541+00:00",[],{"title":772},{"VI":773},"Department of Mechanical Engineering, Faculty of Engineering at Si Racha, Kasetsart University, Si Racha, Thailand",{"title":775},{"VI":776},"Nattapon Chantarapanich",{"id":778,"sortIndex":111,"researcher":22,"roles":779,"affiliations":780,"properties":789},"e7734643-520b-414e-8b2e-b6b636a3e2c6",[150],[781],{"id":22,"sortIndex":23,"affiliation":782,"properties":22},{"id":783,"createTime":784,"updateTime":784,"relativeEntities":785,"slug":22,"properties":786,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"c6f73dc0-0092-4a22-a112-a5e60a710854","2023-12-13T07:28:59.526+00:00",[],{"title":787},{"VI":788},"National Metal and Materials Technology Center (MTEC), Klong Luang, Thailand",{"title":790},{"VI":791},"Kriskrai Sitthiseripratip",{"id":793,"sortIndex":794,"researcher":22,"roles":795,"affiliations":796,"properties":807},"cd141392-1c24-45a0-a238-3204a89d8ca0",4,[150],[797],{"id":22,"sortIndex":23,"affiliation":798,"properties":22},{"id":799,"createTime":800,"updateTime":801,"relativeEntities":802,"slug":803,"properties":804,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"d1907690-f6dc-4300-816d-2c61e15f9983","2023-12-13T07:11:07.005+00:00","2024-10-04T19:53:25.039+00:00",[],"Department-of-Materials-Engineering-Monash-University-Clayton-Australia",{"title":805},{"VI":806},"Department of Materials Engineering, Monash University, Clayton, Australia",{"title":808},{"VI":809},"Qizhi Chen",{"id":811,"sortIndex":113,"researcher":22,"roles":812,"affiliations":813,"properties":819},"dfda195b-d0d9-418b-950f-c0cca16c0783",[150],[814],{"id":22,"sortIndex":23,"affiliation":815,"properties":22},{"id":799,"createTime":800,"updateTime":801,"relativeEntities":816,"slug":803,"properties":817,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":818},{"VI":806},{"title":820},{"VI":821},"George A. 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Int J Mol Sci 15:17938–17962\nOu S-F, Chen C-S, Hosseinkhani H (2013) Surface properties of nano-structural silicon-doped carbon films for biomedical applications\nOu KL, Chu JS, Hosseinkhani H et al (2014) Biomedical nanostructured coating for minimally invasive surgery devices applications: characterization, cell cytotoxicity evaluation and an animal study in rat. Surg Endosc 28:2174–2188. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs00464-014-3450-9\nPawlowski L, Bigan M, Jaworski R et al (2010) Phase evolution of hydroxapatite coatings suspension plasma sprayed using variable parameters in simulated body fluid. Surf Coat Technol 204:1236–1246. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.surfcoat.2009.10.022\nPham DQ, Berndt CC, Gbureck U et al (2019) Mechanical and chemical properties of Baghdadite coatings manufactured by atmospheric plasma spraying. Surf Coat Technol 378:124945. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.surfcoat.2019.124945\nRechendorff K, Hovgaard MB, Foss M et al (2006) Enhancement of protein adsorption induced by surface roughness. Langmuir 22:10885–10888. https:\u002F\u002Fdoi.org\u002F10.1021\u002Fla0621923\nSingh G, Singh S, Prakash S (2011) Surface characterization of plasma sprayed pure and reinforced hydroxyapatite coating on Ti6Al4V alloy. Surf Coat Technol 205:4814–4820. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.surfcoat.2011.04.064\nSingh A, Singh G, Chawla V (2018a) Influence of post coating heat treatment on microstructural, mechanical and electrochemical corrosion behaviour of vacuum plasma sprayed reinforced hydroxyapatite coatings. J Mech Behav Biomed Mater 85:20–36. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jmbbm.2018.05.030\nSingh A, Singh G, Chawla V (2018b) Characterization and mechanical behavior of reinforced hydroxyapatite coatings deposited by vacuum plasma spray on SS-316L alloy. J Mech Behav Biomed Mater 79:273–282. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jmbbm.2018.01.005\nSingh B, Singh G, Singh B (2018c) Analysis of corrosion behavior and surface properties of plasma-sprayed HA\u002FTa coating on CoCr alloy. J Therm Spray Technol. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11666-018-0786-z\nSingh J, Singh S, Singh H (2018d) Characterization and corrosion behavior of functional gradient hydroxyapatite coating. J Therm Spray Technol. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs11666-018-0802-3\nSingh B, Singh G, Singh B (2019a) In vitro investigation of Nb-Ta alloy coating deposited on CoCr alloy for biomedical implants. Surf Coat Technol 377:124932. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.surfcoat.2019.124932\nSingh B, Singh G, Singh B, Bhatia N (2019b) In-vitro assessment of HA-Nb coating on Mg alloy ZK60 for biomedical applications. Mater Chem Phys 231:138–149. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.matchemphys.2019.04.037\nSingh A, Singh G, Chawla V (2020a) Materials Today: proceedings in-vitro performance of reinforced hydroxyapatite coatings deposited using vacuum plasma spray technique on Ti-6Al-4V. Mater Today Proc. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.matpr.2019.12.363\nSingh S, Pandey KK, Islam A, Keshri AK (2020b) Corrosion behaviour of plasma sprayed graphene nanoplatelets reinforced hydroxyapatite composite coatings in simulated body fluid. Ceram Int. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.ceramint.2020.02.139\nSingh S, Prakash C, Singh H (2020c) Deposition of HA-TiO2 by plasma spray on β-phase Ti-35Nb-7Ta-5Zr alloy for hip stem: characterization, mechanical properties, corrosion, and in-vitro bioactivity. Surf Coat Technol 398:126072. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.surfcoat.2020.126072\nSingh J, Chatha SS, Singh H (2021a) Characterization and corrosion behavior of plasma sprayed calcium silicate reinforced hydroxyapatite composite coatings for medical implant applications. Ceram Int 47:782–792. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.ceramint.2020.08.189\nSingh J, Chatha SS, Singh H (2021b) Synthesis and characterization of plasma sprayed functional gradient bioceramic coating for medical implant applications. Ceram Int 47:9143–9155. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.ceramint.2020.12.039\nWang X, Zhou Y, Xia L et al (2014) Fabrication of nano-structured calcium silicate coatings with enhanced stability, bioactivity and osteogenic and angiogenic activity. Colloids Surf B Biointerfaces. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.colsurfb.2014.11.044\nWang H, Zheng Y, Jiang C et al (2017) In vitro corrosion behavior and cytocompatibility of pure Fe implanted with Ta. Surf Coat Technol 320:201–205. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.surfcoat.2017.01.051\nXue W, Liu X, Zheng X, Ding C (2005) In vivo evaluation of plasma-sprayed wollastonite coating. Biomaterials 26:3455–3460. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.biomaterials.2004.09.027\nYang Y, Wang Y, Tian W et al (2015) Influence of composite powders’ microstructure on the microstructure and properties of Al2O3-TiO2 coatings fabricated by plasma spraying. Mater Des 65:814–822. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.matdes.2014.09.078\nYugeswaran S, Yoganand CP, Kobayashi A, Paraskevopoulos KM (2012) Mechanical properties, electrochemical corrosion and in-vitro bioactivity of yttria stabilized zirconia reinforced hydroxyapatite coatings prepared by gas tunnel type plasma spraying. J Mech Behav Biomed Mater 9:22–33. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jmbbm.2011.11.002\nYusuf M, Bakar A, Muhamad N, Rafi M (2019) Incorporation of wollastonite bioactive ceramic with titanium for medical applications: an overview. Mater Sci Eng C 97:884–895. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.msec.2018.12.056",{"EN":881},"The delayed tissue–implant interactions in metallic implants coated with hydroxyapatite (HA) paved the way for the development of alternative bioactive coatings. In this study, bi-layered functional gradient (HA-CS) coating was formulated by the atmospheric plasma spray (APS) process on Ti6Al4V alloy. The HA layer was applied at the metal interface to ensure long-term stability, while the calcium silicate (CS) outer layer was applied to achieve fast tissue–implant interactions. Moreover, single-layered HA and CS coating were also formulated for comparative analysis. The phase compositions, coating microstructure, chemical properties, microhardness, porosity, surface roughness, and in-vitro bioactivity were investigated. The CS top layer showed high porosity and surface roughness with respect to the inner HA layer, which constitutes an optimum microstructure to promote bioactivity. The microhardness of the outer CS layer of HA-CS was 520.3 ± 80.8 HV, while the corresponding value for the inner HA layer was 291.7 ± 45.7 HV. HA-CS and CS coatings demonstrated higher in-vitro bioactivity compared to HA coating. On the contrary, HA coating (3.76 mpy) displayed better corrosion resistance than the HA-CS (4.17 mpy) and CS coatings (4.34 mpy). The in-vitro results indicated that the HA-CS coating could promote the healthy development of osteoblast-like MG-63.",{"EN":883},"Microstructural and in-vitro characteristics of functional calcium silicate topcoat on hydroxyapatite coating for bio-implant applications",{"VOID":885},"10.1007\u002Fs40204-022-00183-w","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-022-00183-w",[888,903,915],{"id":889,"sortIndex":23,"researcher":22,"roles":890,"affiliations":891,"properties":900},"5ba752ce-30b8-4c5e-9a54-2275fe6191a7",[150],[892],{"id":22,"sortIndex":23,"affiliation":893,"properties":22},{"id":894,"createTime":895,"updateTime":895,"relativeEntities":896,"slug":22,"properties":897,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"546e5a93-b3aa-4f53-8230-a100bd07af05","2024-01-30T16:53:14.229+00:00",[],{"title":898},{"VI":899},"Yadavindra College of Engineering, Punjabi University Guru Kashi Campus, Talwandi Sabo, India",{"title":901},{"VI":902},"Jarnail Singh",{"id":904,"sortIndex":111,"researcher":22,"roles":905,"affiliations":906,"properties":912},"9235597a-f74b-4ae3-b124-313e3fbe36a2",[150],[907],{"id":22,"sortIndex":23,"affiliation":908,"properties":22},{"id":894,"createTime":895,"updateTime":895,"relativeEntities":909,"slug":22,"properties":910,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":911},{"VI":899},{"title":913},{"VI":914},"Hazoor Singh",{"id":916,"sortIndex":144,"researcher":22,"roles":917,"affiliations":918,"properties":924},"e34b9ec5-9caa-4a19-a51f-3b38adde5bc3",[150],[919],{"id":22,"sortIndex":23,"affiliation":920,"properties":22},{"id":894,"createTime":895,"updateTime":895,"relativeEntities":921,"slug":22,"properties":922,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":923},{"VI":899},{"title":925},{"VI":926},"Sukhpal Singh Chatha",{"url":886,"publisher":928,"properties":957},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":929,"slug":10,"properties":930,"entityType":20,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"subjectFields":935,"manageAffiliations":936,"indexDatabases":937,"url":22,"thumbnailPath":22,"statistic":952,"gsStatistic":22,"type":121,"analyzePriority":22},[],{"issn":931,"eissn":932,"title":933,"url":934},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},[],[],[938,945],{"id":88,"indexDatabase":939,"url":101,"indexYears":102,"academicFieldIds":944,"indexDatabaseRanking":106},{"id":90,"createTime":91,"updateTime":92,"relativeEntities":940,"label":941,"description":942,"key":98,"publicationTags":943,"standard":22},[],{"EN":95,"VI":95},{"EN":95,"VI":97},[100],[104,105],{"id":68,"indexDatabase":946,"url":83,"indexYears":22,"academicFieldIds":951,"indexDatabaseRanking":22},{"id":70,"createTime":71,"updateTime":72,"relativeEntities":947,"label":948,"description":949,"key":79,"publicationTags":950,"standard":22},[],{"EN":75,"VI":75},{"VI":77,"EN":78},[81,82],[85,86],{"impactFactor":23,"impactFactorByYear":953,"i10Index":23,"i10IndexLast5Year":23,"totalPublication":109,"totalPublicationByYear":954,"totalCitation":23,"totalCitationByYear":955,"totalCitationPerPublication":23,"totalCitationPerPublicationByYear":956,"hindexLast5Year":23,"hindex":23},{},{"2012":111,"2013":112,"2014":52,"2015":113,"2016":114,"2017":115,"2018":64,"2019":116,"2020":115,"2021":117,"2022":118,"2023":111},{},{},{"volume":958,"pages":959},{"VOID":211},{"VOID":960},"95-108","2022-02-22",{"id":963,"createTime":964,"updateTime":965,"relativeEntities":966,"slug":967,"properties":968,"entityType":141,"verifyStatus":142,"verifyTime":965,"verifyNote":143,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"primaryUrl":977,"fullTextUrl":22,"authors":978,"publicationType":178,"publisherRelationship":1021,"citationCount":22,"citationInfo":22,"publishDate":1056,"publishYear":565,"citationAnalyzeStatus":21,"lastCitationAnalyze":22,"indexDatabases":22,"openAccess":22,"references":22,"isForceReanalyzing":216},"6510377b-03bb-4f53-b374-f7c9f768813b","2024-02-18T21:03:21.169+00:00","2025-02-23T23:12:42.116+00:00",[],"Polyurethane-synthesis-for-vascular-application",{"references":969,"abstract":971,"title":973,"doi":975},{"VOID":970},"Ahmed M, Hamilton G, Seifalian MA (2014) The performance of a small-calibre graft for vascular reconstructions in a senescent sheep model. Biomaterials 33:9033–9040\nAskari F (2013) Synthesis and characterizatio of siloxanebased polyurethane nanocomposites; effect of amine chain extenders and carbon nanotube on properties, Ph.D. thesis, Iran Polymer and Petrochemical Institute\nAzevedo HS, Reis RL (2005) Understanding the enzymatic degradation of biodegradable polymers and strategies to control their degradation rate. Biodegradable Systems Tissue Engineering Regenerative Medicine. CRC Press, Boca Raton, pp 179–180\nBai Ch, Zhang X, Dai J, Wang J (2008) Synthesis of UV crosslinkable waterborne siloxane–polyurethanedispersion PDMS-PEDA-PU and the properties of the films. J Coat Technol Res 5(2):251–257\nBarikani M (2006) Polyurethane chemistry, properties, application, timing. Iran Polymer and Petrochemical Research Institute, Tehran\nBoretos JW, Pierce WS (1967) Segmented polyurethane: a new elastomer for biomedical applications. Science 80(3807):1481–1482\nCassim B, Modya G, Bhoola KD (2002) Kallikrein cascade and cytokines in inflamed joints. Pharmacol Ther 94:1–34\nChristenson EM, PatelcS AndersonbJ M, Hiltner A (2006) Enzymatic degradation of poly(ether urethane) and poly(carbonate urethane) by cholesterol esterase. Biomaterials 27:3920–3926\nGrundfest-Broniatowski S (2013) What would surgeons like from materials scientists? Wiley Interdiscip Rev Nanomed Nanobiotechnol 5:299–319\nKannan RY, Salacinski HJ, De Groot J, Clatworthy I, Bozec L, Horton M, Butler PE, Seifalian AM (2006) The antithrombogenic potential of a polyhedral oligomeric silsesquioxane (POSS) nanocomposite. Biomacromolecules 1:215–223\nKapadia MR, Popowich DA, Kibbe MR (2008) Modified prosthetic vascular. Circulation 117:1873–1882\nKidane AG, Burriesci G, Edirisinghe M, Ghanbari H, Bonhoeffer P, Seifalian MA (2009) A novel nanocomposite polymer for development of synthetic heart valve leaflets. Acta Biomater 7:2409–2417\nPrisacariu C (2011) Polyurethane elastomers: from morphology to mechanical aspects. Springer, New York, p 5\nRavi S, Chaikof EL (2010) Biomaterials for vascular tissue engineering. Regen Med 1:107–120\nSolouk A, Cousins BG, Mirzadeh H, Seifalian MA (2011) Surface modification of POSS nanocomposite biomaterials using reactive oxygen plasma treatment for cardiovascular surgical implant applications. Biotechnol Appl Biochem 58:311–327\nSolouk A, Cousins BG, Mirahmadi F, Mirzadeh H, Nadoushan MRJ, Shokrgozar MA, Seifalian MA (2015) Biomimetic modified clinical-grade POSS-PCU nanocomposite polymer for bypass graft applications: a preliminary assessment of endothelial cell adhesion and haemocompatibility. Mater Sci Eng C 46:400–408\nSzycher M (2013) Szycher’S handbook of polyurethanes. Taylor & Francis Group, New York\nTeng S, Qiu Z (2017) Enhanced crystallization and mechanical properties of biodegradable poly (ethylene succinate) by octaisobutyl-polyhedral oligomeric silsesquioxanes in their nanocomposites. Thermochim Acta 649:22–30\nThomson T (2005) Polyurethanes as specialty chemicals: principles and applications. CRC Press, Boca Raton\nWang L, Sun B, Ziemer KS, Barabino GA, Carrier RL (2010) Chemical and physical modifications to poly(dimethylsiloxane) surfaces affect adhesion of Caco-2 cells. J Biomed Mater Res A 93:1260–1271\nZia MK, Ahmad A, Anjum S, Zuber M, Naveed Anjum M (2014) Synthesis and characterization of siloxane-based polyurethane elastomers using hexamethylenediisocyanate. J Elast Plast 47:1–11",{"EN":972},"Three polyurethane formulations were prepared on the basis of siloxane; two formulations contained 1% and 3% of a hydroxyl functionalized polyhedral oligomeric silsesquioxane [POSS (ROH)2] nano-particles (as a co-chain extender) and one was without nano-particle. Structures of the polyurethanes were characterized by FTIR and SEM. The effect of POSS nano-particles on properties of the synthesized PUs was examined for vascular applications by tensile test, contact angle, SEM, AFM and endothelial cells viability evaluation. Properties of the polyurethane with 1% POSS were compared with those of PU without POSS and the results showed 66% increase in the elongation-at-break, 53% increase in tensile strength and 33% increase in modulus, 9.45% increase in contact angle, 76.7% reduction in surface roughness and 9.46% increase in cell viability. It was also shown that a polyurethane containing 1% of POSS nano-particles in its structure developed the highest hydrophobicity, which resulted in its lowest potential for thrombosis. \n                  \n                    \n                      \n                    \n                  \n                ",{"EN":974},"Polyurethane synthesis for vascular application",{"VOID":976},"10.1007\u002Fs40204-018-0101-6","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-018-0101-6",[979,994,1009],{"id":980,"sortIndex":111,"researcher":22,"roles":981,"affiliations":982,"properties":991},"6e6e98d1-8d71-452f-8e8d-039004f32010",[150],[983],{"id":22,"sortIndex":23,"affiliation":984,"properties":22},{"id":985,"createTime":986,"updateTime":986,"relativeEntities":987,"slug":22,"properties":988,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"9258a0b5-dc49-491a-9148-e404005a6dee","2024-02-18T21:03:21.217+00:00",[],{"title":989},{"VI":990},"Biomaterials Department, Iran Polymer and Petrochemical Institute, Tehran-Karaj Hwy, Tehran, Iran",{"title":992},{"VI":993},"Parvin Shokrolahi",{"id":995,"sortIndex":144,"researcher":22,"roles":996,"affiliations":997,"properties":1006},"c7fe76cf-07e7-4e00-98af-cd5b7847ecc5",[150],[998],{"id":22,"sortIndex":23,"affiliation":999,"properties":22},{"id":1000,"createTime":1001,"updateTime":1001,"relativeEntities":1002,"slug":22,"properties":1003,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"62813c12-f629-413c-9447-8f51d4324533","2024-02-18T21:03:21.205+00:00",[],{"title":1004},{"VI":1005},"Polymer Science Department, Iran Polymer and Petrochemical Institute, Tehran-Karaj Hwy, Tehran, Iran",{"title":1007},{"VI":1008},"Fahimeh Askari",{"id":1010,"sortIndex":23,"researcher":22,"roles":1011,"affiliations":1012,"properties":1018},"50b2c302-f016-4fcf-a68f-c9c5250fa4ab",[150],[1013],{"id":22,"sortIndex":23,"affiliation":1014,"properties":22},{"id":1000,"createTime":1001,"updateTime":1001,"relativeEntities":1015,"slug":22,"properties":1016,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":1017},{"VI":1005},{"title":1019},{"VI":1020},"Zahra Zaredar",{"url":977,"publisher":1022,"properties":1051},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1023,"slug":10,"properties":1024,"entityType":20,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"subjectFields":1029,"manageAffiliations":1030,"indexDatabases":1031,"url":22,"thumbnailPath":22,"statistic":1046,"gsStatistic":22,"type":121,"analyzePriority":22},[],{"issn":1025,"eissn":1026,"title":1027,"url":1028},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},[],[],[1032,1039],{"id":88,"indexDatabase":1033,"url":101,"indexYears":102,"academicFieldIds":1038,"indexDatabaseRanking":106},{"id":90,"createTime":91,"updateTime":92,"relativeEntities":1034,"label":1035,"description":1036,"key":98,"publicationTags":1037,"standard":22},[],{"EN":95,"VI":95},{"EN":95,"VI":97},[100],[104,105],{"id":68,"indexDatabase":1040,"url":83,"indexYears":22,"academicFieldIds":1045,"indexDatabaseRanking":22},{"id":70,"createTime":71,"updateTime":72,"relativeEntities":1041,"label":1042,"description":1043,"key":79,"publicationTags":1044,"standard":22},[],{"EN":75,"VI":75},{"VI":77,"EN":78},[81,82],[85,86],{"impactFactor":23,"impactFactorByYear":1047,"i10Index":23,"i10IndexLast5Year":23,"totalPublication":109,"totalPublicationByYear":1048,"totalCitation":23,"totalCitationByYear":1049,"totalCitationPerPublication":23,"totalCitationPerPublicationByYear":1050,"hindexLast5Year":23,"hindex":23},{},{"2012":111,"2013":112,"2014":52,"2015":113,"2016":114,"2017":115,"2018":64,"2019":116,"2020":115,"2021":117,"2022":118,"2023":111},{},{},{"volume":1052,"pages":1054},{"VOID":1053},"7",{"VOID":1055},"269-278","2018-10-22",{"id":1058,"createTime":1059,"updateTime":1060,"relativeEntities":1061,"slug":1062,"properties":1063,"entityType":141,"verifyStatus":142,"verifyTime":1060,"verifyNote":143,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"primaryUrl":1072,"fullTextUrl":22,"authors":1073,"publicationType":178,"publisherRelationship":1161,"citationCount":22,"citationInfo":22,"publishDate":1196,"publishYear":1197,"citationAnalyzeStatus":21,"lastCitationAnalyze":22,"indexDatabases":22,"openAccess":22,"references":22,"isForceReanalyzing":216},"76c1e86f-854a-4dc0-8be0-84f930f1dfd8","2023-12-22T22:38:50.886+00:00","2024-12-19T22:49:54.114+00:00",[],"Different-zeolite-systems-for-colon-cancer-therapy-monitoring-of-ion-release-cytotoxicity-and-drug-release-behavior",{"references":1064,"abstract":1066,"title":1068,"doi":1070},{"VOID":1065},"Absher M, Mortara M (1980) Effect of silica on the proliferative behavior of human lung fibroblasts. Vitro Cell Dev Biol Plant 16:371–376\nAl-Thawabeia RA, Hodali HA (2015) Use of zeolite ZSM-5 for loading and release of 5-fluorouracil. J Chem 2015:403597. https:\u002F\u002Fdoi.org\u002F10.1155\u002F2015\u002F403597\nBanerjee A, Pathak S, Subramanium VD, Dharanivasan G, Murugesan R, Verma RS (2017) Strategies for targeted drug delivery in treatment of colon cancer: current trends and future perspectives. Drug Discov Today 22:1224–1232\nBeran S, Dubsky J (1979) Quantum chemical study of the electronic structure of Na-X and Na-Y zeolites. J Phys Chem 83:2538–2544\nBougeard D, Smirnov KS, Geidel E (2000) Vibrational spectra and structure of kaolinite: a computer simulation study. J Phys Chem B 104:9210–9217\nChandrasekhar S, Raghavan P, Sebastian G, Damodaran A (1997) Brightness improvement studies on ‘kaolin based’zeolite 4A. Appl Clay Sci 12:221–231\nČimek A, Subotić B, Šmit I, Tonejc A, Aiello R, Crea F et al (1997) Dissolution of high-silica zeolites in alkaline solutions II. Dissolution of ‘activated’ silicalite-1 and ZSM-5 with different aluminum content. Microporous Mater 8:159–169\nCosta P, Lobo JMS (2001) Modeling and comparison of dissolution profiles. Eur J Pharm Sci 13:123–133\nDatt A, Burns EA, Dhuna NA, Larsen SC (2013) Loading and release of 5-fluorouracil from HY zeolites with varying SiO 2\u002FAl2O3 ratios. Microporous Mesoporous Mater 167:182–187\nEl-Ghannam A, Ricci K, Malkawi A, Jahed K, Vedantham K, Wyan H et al (2010) A ceramic-based anticancer drug delivery system to treat breast cancer. J Mater Sci Mater Med 21:2701–2710\nEl-Sherbiny I, Lins R, Abdel-Bary E, Harding D (2005) Preparation, characterization, swelling and in vitro drug release behaviour of poly [N-acryloylglycine-chitosan] interpolymeric pH and thermally-responsive hydrogels. Eur Polym J 41:2584–2591\nFirst EL, Gounaris CE, Wei J, Floudas CA (2011) Computational characterization of zeolite porous networks: an automated approach. Phys Chem Chem Phys 13:17339–17358\nHiguchi T (1963) Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci 52:1145–1149\nKaravasili C, Amanatiadou EP, Kontogiannidou E, Eleftheriadis GK, Bouropoulos N, Pavlidou E et al (2017) Comparison of different zeolite framework types as carriers for the oral delivery of the poorly soluble drug indomethacin. Int J Pharm 528:76–87\nKhodaverdi E, Soleimani HA, Mohammadpour F, Hadizadeh F (2016) Synthetic zeolites as controlled-release delivery systems for anti-inflammatory drugs. Chem Biol Drug Des 87:849–857\nKralj M, Pavelic K (2003) Medicine on a small scale: how molecular medicine can benefit from self-assembled and nanostructured materials. EMBO Rep 4:1008–1012\nKühl G, Weitkamp J, Puppe L (1999) Catalysis and zeolites: fundamentals and applications. Springer, Berlin\nKuronen M, Harjula R, Jernström J, Vestenius M, Lehto J (2000) Effect of the framework charge density on zeolite ion exchange selectivities. Phys Chem Chem Phys 2:2655–2659\nLi S, Wang A, Jiang W, Guan Z (2008) Pharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticles. BMC Cancer 8:103\nMarques MR, Loebenberg R, Almukainzi M (2011) Simulated biological fluids with possible application in dissolution testing. Dissolution Technol 18:15–28\nMumpton FA (1999) La roca magica: uses of natural zeolites in agriculture and industry. Proc Natl Acad Sci 96:3463–3470\nMunthali MW, Elsheikh MA, Johan E, Matsue N (2014) Proton adsorption selectivity of zeolites in aqueous media: effect of Si\u002FAl ratio of zeolites. Molecules 19:20468–20481\nMunthali MW, Johan E, Matsue N (2015) Proton adsorption selectivity of zeolites in aqueous media: effect of exchangeable cation species of zeolites. Environments 2:91–104\nNagy A, Harrison A, Sabbani S, Munson RS Jr, Dutta PK, Waldman WJ (2011) Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action. Int J Nanomed 6:1833–1852\nPasquino R, Di Domenico M, Izzo F, Gaudino D, Vanzanella V, Grizzuti N et al (2016) Rheology-sensitive response of zeolite-supported anti-inflammatory drug systems. Colloids Surf B Biointerfaces 146:938–944\nPerminova IV, Hatfield K, Hertkorn N (2005) Use of humic substances to remediate polluted environments: from theory to practice. Springer, Berlin\nRimoli MG, Rabaioli MR, Melisi D, Curcio A, Mondello S, Mirabelli R et al (2008) Synthetic zeolites as a new tool for drug delivery. J Biomed Mater Res, Part A 87:156–164\nSağir T, Huysal M, Durmus Z, Kurt BZ, Senel M, Isık S (2016) Preparation and in vitro evaluation of 5-flourouracil loaded magnetite–zeolite nanocomposite (5-FU-MZNC) for cancer drug delivery applications. Biomed Pharmacother 77:182–190\nSanders L (1990) Drug delivery systems and routes of administration of peptide and protein drugs. Eur J Drug Metab Pharmacokinet 15:95–102\nSantos C, Martins M, Franke R-P, Almeida M, Costa M (2009) Calcium phosphate granules for use as a 5-fluorouracil delivery system. Ceram Int 35:1587–1594\nSathupunya M, Gulari E, Jamieson A, Wongkasemjit S (2004) Microwave-assisted preparation of zeolite K–H from alumatrane and silatrane. Microporous Mesoporous Mater 69:157–164\nSpanakis M, Bouropoulos N, Theodoropoulos D, Sygellou L, Ewart S, Moschovi AM et al (2014) Controlled release of 5-fluorouracil from microporous zeolites. Nanomed Nanotechnol Biol Med 10:197–205\nThabrew MI, Hughes RD, Mcfarlane IG (1997) Screening of hepatoprotective plant components using a HepG2 cell cytotoxicity assay. J Pharm Pharmacol 49:1132–1135\nThom DC, Davies JE, Santerre JP, Friedman S (2003) The hemolytic and cytotoxic properties of a zeolite-containing root filling material in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:101–108\nThomassen LC, Napierska D, Dinsdale D, Lievens N, Jammaer J, Lison D et al (2012) Investigation of the cytotoxicity of nanozeolites A and Y. Nanotoxicology 6:472–485\nVellaian Karuppiah NK, Manavalan R (2012) In-vitro and simulated in vivo dissolution of dipyridamole extended release capsules. Int J Pharm Sci Rev Res 13:5\nVilaça N, Amorim R, Machado AF, Parpot P, Pereira MF, Sardo M et al (2013) Potentiation of 5-fluorouracil encapsulated in zeolites as drug delivery systems for in vitro models of colorectal carcinoma. Colloids Surfaces B Biointerfaces 112:237–244\nWenande E, Olesen UH, Nielsen MM, Janfelt C, Hansen SH, Anderson RR et al (2017) Fractional laser-assisted topical delivery leads to enhanced, accelerated and deeper cutaneous 5-fluorouracil uptake. Expert Opin Drug Deliv 14:307–317\nWilkin R, Barnes H (1998) Solubility and stability of zeolites in aqueous solution: I. Analcime, Na-, and K-clinoptilolite. Am Mineral 83:746–761\nWinocur G, Vardy J, Binns MA, Kerr L, Tannock I (2006) The effects of the anti-cancer drugs, methotrexate and 5-fluorouracil, on cognitive function in mice. Pharmacol Biochem Behav 85:66–75\nYoussef H, Ibrahim D, Komarneni S (2008) Microwave-assisted versus conventional synthesis of zeolite A from metakaolinite. Microporous Mesoporous Mater 115:527–534",{"EN":1067},"Three types of oral administrated micronized zeolites [ZSM-5, zeolite A and Faujasite NaX (ZSM-5, ZA and ZX, respectively)] were prepared as anticancer 5-fluorouracil (5-Fu) delivery systems for colon cancer treatment. They were prepared by economically widespread and cheap natural resource, kaolin, at low temperatures, using microwave advanced tool. The obtained powders were characterized by XRD, SEM\u002FEDX and BET; meanwhile, their degradation was investigated in two gastric fluids; FaSSGF (pH 1.6) and FeSSGF (pH 5), through concentration measurement of their solution disintegrated elemental constituents of Na+, Al3+ and Si4+ ions. Also, the processes of drug release and mechanism in both solutions were investigated. Moreover, the inhibition action of 5-Fu-free and 5-Fu-conjugated zeolites on colon cancer cells (CaCo-2) was estimated. The results showed that, the prepared zeolites possessed high surface areas of 526, 250, and 578 m2\u002Fg for ZSM-5, ZA and ZX, respectively. Although, zeolite structures seemed significantly stable, their frameworks seemed more likely reactive with time. The ions and drug release for zeolites occurred in successively two stages and found to be pH dependent, where the drug and zeolite ions were significantly of higher values in the more acidic media of the gastric solution (pH 1.6) than those of the mild acidic one (pH 5). The obtained activity indicated no cytotoxic affinity for all the prepared zeolite types. Accordingly, the synthesized zeolite frameworks are proposed to be of strong potential drug delivery vehicle for the treatment of gastrointestinal cancer. \n                  \n                    \n                      \n                    \n                  \n                ",{"EN":1069},"Different zeolite systems for colon cancer therapy: monitoring of ion release, cytotoxicity and drug release behavior",{"VOID":1071},"10.1007\u002Fs40204-019-0115-8","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs40204-019-0115-8",[1074,1089,1106,1121,1136,1148],{"id":1075,"sortIndex":111,"researcher":22,"roles":1076,"affiliations":1077,"properties":1086},"faac6e68-bdd9-490c-9f9a-171d67c3e40b",[150],[1078],{"id":22,"sortIndex":23,"affiliation":1079,"properties":22},{"id":1080,"createTime":1081,"updateTime":1081,"relativeEntities":1082,"slug":22,"properties":1083,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"cf00f064-e70b-4cc0-9c22-aca89e5aca2e","2023-12-22T22:38:50.900+00:00",[],{"title":1084},{"VI":1085},"Ceramics, Refractories and Building Materials Department, National Research Centre, Dokki, Cairo, Egypt",{"title":1087},{"VI":1088},"H. F. Youssef",{"id":1090,"sortIndex":144,"researcher":22,"roles":1091,"affiliations":1092,"properties":1103},"9618e523-6431-4828-a83c-ca5b5fa6c7a0",[150],[1093],{"id":22,"sortIndex":23,"affiliation":1094,"properties":22},{"id":1095,"createTime":1096,"updateTime":1097,"relativeEntities":1098,"slug":1099,"properties":1100,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"961bf4d2-4b3c-43c5-8faf-1e48cbbd0237","2024-02-07T10:22:46.645+00:00","2024-12-05T18:46:22.283+00:00",[],"Glass-Research-Department-National-Research-Centre-Dokki-Cairo-Egypt",{"title":1101},{"VI":1102},"Glass Research Department, National Research Centre, Dokki, Cairo, Egypt",{"title":1104},{"VI":1105},"M. M. Farag",{"id":1107,"sortIndex":794,"researcher":22,"roles":1108,"affiliations":1109,"properties":1118},"8b736725-17f6-45d1-8d92-c64e1d545149",[150],[1110],{"id":22,"sortIndex":23,"affiliation":1111,"properties":22},{"id":1112,"createTime":1113,"updateTime":1113,"relativeEntities":1114,"slug":22,"properties":1115,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"68daabb0-91bd-498d-bfe7-8ec83b7f6e23","2023-12-22T22:38:50.943+00:00",[],{"title":1116},{"VI":1117},"Pharmacognosy Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo, Egypt",{"title":1119},{"VI":1120},"M. M. Mounier",{"id":1122,"sortIndex":113,"researcher":22,"roles":1123,"affiliations":1124,"properties":1133},"dd2e69ae-0910-428c-88d3-db667805e944",[150],[1125],{"id":22,"sortIndex":23,"affiliation":1126,"properties":22},{"id":1127,"createTime":1128,"updateTime":1128,"relativeEntities":1129,"slug":22,"properties":1130,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"9dd3cf45-57f7-43c4-8c83-1e19fdc43554","2023-12-22T22:38:50.932+00:00",[],{"title":1131},{"VI":1132},"Physical Chemistry, Faculty of Science, Cairo University, Cairo, Egypt",{"title":1134},{"VI":1135},"S. A. Salih",{"id":1137,"sortIndex":23,"researcher":22,"roles":1138,"affiliations":1139,"properties":1145},"8cf97bdd-6f76-4d5d-9ecb-99ce1eb1485a",[150],[1140],{"id":22,"sortIndex":23,"affiliation":1141,"properties":22},{"id":1080,"createTime":1081,"updateTime":1081,"relativeEntities":1142,"slug":22,"properties":1143,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":1144},{"VI":1085},{"title":1146},{"VI":1147},"A. G. Abd-Elsatar",{"id":1149,"sortIndex":1150,"researcher":22,"roles":1151,"affiliations":1152,"properties":1158},"647d9a86-5d09-4566-907e-f3e5e6a1ce1b",5,[150],[1153],{"id":22,"sortIndex":23,"affiliation":1154,"properties":22},{"id":1080,"createTime":1081,"updateTime":1081,"relativeEntities":1155,"slug":22,"properties":1156,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},[],{"title":1157},{"VI":1085},{"title":1159},{"VI":1160},"E. El-Meliegy",{"url":1072,"publisher":1162,"properties":1191},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1163,"slug":10,"properties":1164,"entityType":20,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"subjectFields":1169,"manageAffiliations":1170,"indexDatabases":1171,"url":22,"thumbnailPath":22,"statistic":1186,"gsStatistic":22,"type":121,"analyzePriority":22},[],{"issn":1165,"eissn":1166,"title":1167,"url":1168},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},[],[],[1172,1179],{"id":88,"indexDatabase":1173,"url":101,"indexYears":102,"academicFieldIds":1178,"indexDatabaseRanking":106},{"id":90,"createTime":91,"updateTime":92,"relativeEntities":1174,"label":1175,"description":1176,"key":98,"publicationTags":1177,"standard":22},[],{"EN":95,"VI":95},{"EN":95,"VI":97},[100],[104,105],{"id":68,"indexDatabase":1180,"url":83,"indexYears":22,"academicFieldIds":1185,"indexDatabaseRanking":22},{"id":70,"createTime":71,"updateTime":72,"relativeEntities":1181,"label":1182,"description":1183,"key":79,"publicationTags":1184,"standard":22},[],{"EN":75,"VI":75},{"VI":77,"EN":78},[81,82],[85,86],{"impactFactor":23,"impactFactorByYear":1187,"i10Index":23,"i10IndexLast5Year":23,"totalPublication":109,"totalPublicationByYear":1188,"totalCitation":23,"totalCitationByYear":1189,"totalCitationPerPublication":23,"totalCitationPerPublicationByYear":1190,"hindexLast5Year":23,"hindex":23},{},{"2012":111,"2013":112,"2014":52,"2015":113,"2016":114,"2017":115,"2018":64,"2019":116,"2020":115,"2021":117,"2022":118,"2023":111},{},{},{"volume":1192,"pages":1194},{"VOID":1193},"8",{"VOID":1195},"101-113","2019-05-20",2019,{"id":1199,"createTime":1200,"updateTime":1201,"relativeEntities":1202,"slug":1203,"properties":1204,"entityType":141,"verifyStatus":142,"verifyTime":1201,"verifyNote":143,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23,"primaryUrl":1213,"fullTextUrl":22,"authors":1214,"publicationType":178,"publisherRelationship":1256,"citationCount":22,"citationInfo":22,"publishDate":1290,"publishYear":1197,"citationAnalyzeStatus":21,"lastCitationAnalyze":22,"indexDatabases":22,"openAccess":22,"references":22,"isForceReanalyzing":216},"eb7be72b-2e48-4368-8aa2-8b9d3c3cf4bb","2023-12-05T13:20:03.943+00:00","2024-12-17T22:40:09.162+00:00",[],"The-effect-of-sodium-and-magnesium-ions-on-the-properties-of-calcium-phosphate-biomaterials",{"references":1205,"abstract":1207,"title":1209,"doi":1211},{"VOID":1206},"Bagherpour I, Naghib SM, Yaghtin AH (2018) Synthesis and characterisation of nanostructured hardystonite coating on stainless steel for biomedical application. IET Nanobiotechnol 12:895–898\nBarinov SM (2010) Calcium phosphate-based ceramic and composite materials for medicine. Russ Chem Rev 79:13–21\nBarinov SM, Komlev VS (2014a) Calcium phosphate bone cements (a review): I. Binder Syst Materialoved 1:33–39\nBarinov SM, Komlev VS (2014b) Calcium phosphate bone cements (a review): II. Compos Med Appl Materialoved 2:35–41\nBarinov SM, Komlev VS (2016) Approaches to the fabrication of calcium phosphate-based porous materials for bone tissue regeneration. Inorg Mater 52(4):339–346\nBjornoy SH, Bassett DC, Ucar S, Andreassen JP, Sikorski P (2016) A correlative spatiotemporal microscale study of calcium phosphate formation and transformation within an alginate hydrogel matrix. Acta Biomater 44:254–259\nBorilo LP, Lyutova ES, Spivakova LN (2016) Study of biological properties of thin-film materials on the basis of the SiO2–P2O5–CaO system. Key Eng Mater 683:427–433\nChrysafi R, Perraki Th (2007) Sol–gel preparation of 2CaO–SiO2. J Eur Ceram Soc 27:1707–1710\nDorozhkin SV (2010) Bioceramics of calcium orthophosphates. Biomaterials 31:1465–1468\nDorozhkin SV (2016) Calcium orthophosphate-based bioceramics and biocomposites. Wiley, New York\nEvdokimov PV, Putlyaev VI, Ivanov VK, Garshev AP, Shatalova TB, Orlov NK, Klimashina ES, Safronova TV (2014) Phase equilibria in the tricalcium phosphate-mixed calcium sodium (potassium) phosphate systems. Russ J Inorg Chem 59:1219–1228\nJmal N, Bouaziz J (2017) Synthesis, characterization and bioactivity of a calcium–phosphate glass-ceramics obtained by the sol–gel processing method. Mater Sci Eng 71:279–286\nKokubo T, Kushitani H, Sakka S (1990) Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W3. J Biomed Mater Res 24:721–732\nKomlev VS, Rau JV, Fosca M, Fomin AS, Gurin AN, Barinov SM, Caminiti R (2012) Single-phase bone cement based on dicalcium phosphate dihydrate powder and sodium silicate solution. Mater Lett 73:115–123\nKondratowicz T (2007) Structural changes in sodium-calcium-silicate glass after adding Si3N4. Opt Appl 37:41\nKukueva EV, Putlyaev VI, Tikhonov AA, Safronova TV (2017) Octacalcium phosphate as a precursor for the fabrication of composite bioceramics. Inorg Mater 53(2):212–219\nLetaпef N, Lucas-Girot A, Oudadesse H, Dorbez-Sridi R, Boullay P (2014) Investigation of the surfactant type effect on characteristics and bioactivity of new mesoporous bioactive glass in the ternary system SiO2–CaO–P2O5: structural, textural and reactivity studies. Acta Biomater 195:109–111\nMatsumoto N, Sato K, Yoshida K, Hashimoto K, Toda Y (2009) Preparation and characterization of β-tricalcium phosphate co-doped with monovalent and divalent antibacterial metal ions. Acta Biomater 5:3157–3164\nMoghanian A, Sedghi A, Ghorbanoghli A, Salari E (2018) The effect of magnesium content on in vitro bioactivity, biological behavior and antibacterial activity of sol–gel derived 58S bioactive glass. Ceram Int 44:9422–9433\nNarayanan R, Seshadri SK, Kwon BY, Kim KH (2008) Calcium phosphate-based coatings on titanium and its alloys. J Biomed Mater Res 85:279–299\nPereira MM, Clark AE, Hench LL (1994) Homogeneity of bioactive sol–gel derived glasses in the system CaO–P2O5–SiO2. J Mater Synth Proc 2(30):189–196\nPet’kov VI, Shchelokov IA, Asabina EA, Kurazhkovskaya VS, Rusakov DA, Pokholok KV, Lazoryak BI (2006) Synthesis and phase formation in M0.5(1 x)FexTi2–x(PO4)3 phosphate series. Russ J Inorg Chem 51(12):1855–1863\nPetrović R, Janacković D, Zec S, Drmanić S, Lj Kostić-Gvozdenović (2001) Phasetransformation kinetics in triphasic cordierite gel. J Mater Res 16:451–458\nPetrovskaya T, Borilo L, Kozik V (2016) The processes in film-forming solution based on tetraethoxysilane, phosphoric acid and calcium chloride. AIP Conf Proc 1771:0200061\nPopa AC, Stan GE, Husanu MA, Mercioniu I, Santos LF, Fernandes HR, Ferreira JMF (2017) Bioglass implant-coating interactions in synthetic physiological fluids with varying degrees of biomimicry. Int J Nanomed 12:683–707\nVallet-Regi M, Gonzalez-Calbet JM (2004) Calcium phosphates as substitution of bone tissues. Prog Solid State Chem 32:1\nVijayalakshmi U, Rajeswari S (2006) Preparation and characterization of microcrystalfine hydroxyapatite using sol gel method. Trends Biomater Artif Organs 19(2):57–62\nXynos ID, Hukkanen MVJ (2000) Bioglass 45S5 stimulates osteoblast turnover and enhances bone formation in vitro: implications and applications for bone tissue engineering. Calcif Tissue Int 67:321–329\nYashima M, Sakai A, Kamiyama T, Hoshikawa A (2003) Crystal structure analysis of β-tricalcium phosphate Ca3(PO4)2 by neutron powder diffraction. J Solid State Chem 175:272\nZhang D, Wang M, Ren GJ, Song EJ (2013) General relation between tensile strength and fatigue strength of metallic materials. J Mater Sci Eng 33:4677–4682",{"EN":1208},"A calcium–phosphate system was obtained by sol–gel method from 0.4 M solutions based on ethyl alcohol, tetraethoxysilane, phosphoric acid, calcium nitrate, and magnesium nitrate, sodium chloride. Compositions with different contents of CaO, Na2O, and MgO were prepared. After maturation of the solutions, heat treatments were applied at 60 °C for 30 min; and followed by 600 °C and 800 °C for 1 h. Solution with 20 wt% MgO was found suitable for film production. The physicochemical processes of the formation of materials were studied, including the main stages: removal of physically bound and chemically bound water, combustion of alcohol and the products of thermo-oxidative destruction of ethoxy groups, and crystallization processes. The phase composition and structure of the films obtained were established at 600 °C and above when crystalline forms of SiO2, CaSiO3, Ca2P2O7, and complex phosphates were fixed. In the system with the addition of magnesium ions, β-cristobalite SiO2 and stenfieldt Mg3Ca3(PO4)4 were detected; however, a crystalline sample could only be obtained at 800 °C. In the system with sodium ions, chemical compounds Ca5(PO4)3Cl, NaCl, and SiO2 were determined. A uniform film coating was formed on the surface of the substrate. The introduction of sodium oxide into the SiO2–P2O5–CaO system increased the bioactivity of the materials obtained.",{"EN":1210},"The effect of sodium and magnesium ions on the properties of calcium–phosphate biomaterials",{"VOID":1212},"10.1007\u002Fs40204-019-0117-6","http:\u002F\u002Flink.springer.com\u002F10.1007\u002Fs40204-019-0117-6",[1215,1232,1244],{"id":1216,"sortIndex":23,"researcher":22,"roles":1217,"affiliations":1218,"properties":1229},"697de56d-923c-495d-ac1a-06a8f869a669",[150],[1219],{"id":22,"sortIndex":23,"affiliation":1220,"properties":22},{"id":1221,"createTime":1222,"updateTime":1223,"relativeEntities":1224,"slug":1225,"properties":1226,"entityType":51,"verifyStatus":21,"verifyTime":22,"verifyNote":22,"syncStatus":21,"languages":22,"translateLanguages":22,"viewCount":23},"18f1600c-bfa2-48b8-86eb-ce7b8cdcf86a","2023-12-24T00:43:29.705+00:00","2024-12-10T23:03:11.246+00:00",[],"National-Research-Tomsk-State-University-Tomsk-Russia",{"title":1227},{"VI":1228},"National Research Tomsk State University, Tomsk, Russia",{"title":1230},{"VI":1231},"Ekaterina 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