[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_2357a78e-cf1e-42c0-87d2-59200df59136":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:2357a78e-cf1e-42c0-87d2-59200df59136,\"}":173},{"code":4,"data":5,"meta":20},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":22,"manageAffiliations":29,"indexDatabases":45,"url":20,"thumbnailPath":20,"statistic":82,"gsStatistic":20,"type":172,"analyzePriority":20},"2357a78e-cf1e-42c0-87d2-59200df59136","2024-04-08T08:13:00.729+00:00","2025-11-21T09:52:10.415+00:00",[],"Photochemical-Photobiological-Sciences",{"issn":12,"title":14,"url":16},{"VOID":13},"14749092",{"EN":15},"Photochemical & Photobiological Sciences",{"VOID":17},"https:\u002F\u002Flink.springer.com\u002Fjournal\u002F43630","PUBLISHER","PENDING",null,0,[23],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":25,"label":26,"description":28,"parentId":20,"standard":20,"scholarHubFieldId":20},"61124dd3-23c5-4a8e-b8e9-7371b135f74f",[],{"EN":27},"Physical and Theoretical Chemistry",{},[30,38],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":32,"slug":20,"properties":33,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":36,"statistic":20},"ca0dc894-2cfd-4536-8558-d78518e3e721",[],{"title":34},{"EN":35},"Springer International Publishing AG",[37],"9a7c7208-b28a-42c2-a634-5a7f90eee3ab",{"id":39,"createTime":20,"updateTime":20,"relativeEntities":40,"slug":20,"properties":41,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":44,"statistic":20},"8e7fce10-23c9-4f81-8998-abcf28ea16a0",[],{"title":42},{"EN":43},"Springer Nature",[37],[46,63],{"id":47,"indexDatabase":48,"url":58,"indexYears":59,"academicFieldIds":60,"indexDatabaseRanking":62},"814b360b-7e70-4784-9d93-2057731c9ceb",{"id":49,"createTime":20,"updateTime":20,"relativeEntities":50,"label":51,"description":53,"key":55,"publicationTags":56,"standard":20},"3c7051d4-eb7d-4c57-a56b-36fc74c5d1e9",[],{"EN":52,"VI":52},"Scopus - Elsevier",{"EN":52,"VI":54},"Cơ sở dữ liệu Scopus thuộc Elsevier","scopus",[57],"SCOPUS","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21429","2002-2025",[61],"b4efb51f-da98-4990-a79e-a5f531f11b28","SCOPUS__Q2",{"id":64,"indexDatabase":65,"url":77,"indexYears":20,"academicFieldIds":78,"indexDatabaseRanking":20},"6bb73102-a8ca-4b44-9daa-7a062126c170",{"id":66,"createTime":20,"updateTime":20,"relativeEntities":67,"label":68,"description":70,"key":73,"publicationTags":74,"standard":20},"a4921856-b128-4d9f-8f1f-e80813d3bbd4",[],{"EN":69,"VI":69},"ISI\u002FSCIE - Science Citation Index Expanded",{"EN":71,"VI":72},"SCIE database","Cơ sở dữ liệu SCIE","scie",[75,76],"SCIE","ISI","https:\u002F\u002Fmjl.clarivate.com\u002Fsearch-results?issn=1474-905X",[79,80,81],"10e9c71e-2256-419c-bdd2-a39e436e76e3","bb53981f-29b6-4b16-89ea-99cf1e4357c7","d875699a-416e-4523-bcb9-17b1b64de061",{"impactFactor":21,"impactFactorByYear":83,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":98,"totalCitation":121,"totalCitationByYear":122,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":147,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},1.39,1.3,0.62,0.34,0.41,0.54,0.89,2.61,3.14,0.35,0.16,317,36,2858,{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},87,128,122,106,92,113,121,152,133,27,160,130,132,117,31,26,40,587,100,135,111,28,16176,{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},1256,647,1206,1175,519,881,1652,789,1117,1421,1290,555,576,507,495,523,415,590,265,103,89,19,1,5.66,{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},14.44,5.05,9.89,11.08,5.64,7.8,13.65,5.19,8.4,52.63,8.49,3.47,4.43,3.84,4.23,16.87,15.96,14.75,0.45,1.03,0.66,0.17,0.04,64,"JOURNAL",{"meta":174,"data":176},{"total":175},"2866",[177,413,613,732,848,1166,1310,1496,1917,2137],{"id":178,"createTime":179,"updateTime":180,"relativeEntities":181,"slug":182,"properties":183,"entityType":192,"verifyStatus":193,"verifyTime":194,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":196,"fullTextUrl":20,"authors":197,"publicationType":245,"publisherRelationship":246,"citationCount":293,"citationInfo":294,"publishDate":297,"publishYear":295,"citationAnalyzeStatus":298,"lastCitationAnalyze":180,"indexDatabases":299,"openAccess":20,"references":300,"isForceReanalyzing":412},"be26f4c7-1032-4fb7-8027-680a9bfb964a","2024-02-19T22:17:55.459+00:00","2026-08-16T03:06:33.773+00:00",[],"Light-induced-body-color-change-in-developing-zebrafish",{"abstract":184,"title":186,"gsPaper":188,"doi":190},{"EN":185},"In response to ambient light levels, many lower vertebrates darken or lighten their body colors by regulating dispersion or aggregation, respectively, of melanin granules (melanosomes) in the melanophore. This physiological reaction is mediated by photoreception in the eyes, the pineal gland, the deep brain and the melanophores themselves, depending on species and their developmental stages. In this study, we established a method for quantitative measurement of the light-induced body color change in zebrafish larvae. From 2 days post-fertilization (dpf), the dermal melanophores responded to light illumination, but the response patterns and temporal profiles changed across the developmental stages. At 2 dpf, light illumination on larvae induced a relatively fast dispersion of the pigments in the melanophores, whereas continuous illumination additionally caused a delayed pigment aggregation at 3 dpf or later stages. Removal of the eyes abolished the light-dependent pigment aggregation but not the pigment dispersion at 5 dpf, while the pigment dispersion at 2 dpf was retained even in the isolated tail. These results suggest that the pigment dispersion is triggered by photoreception intrinsic to the melanophores and that the pigment aggregation is mediated by photoreception in the eyes. The monitoring system developed in this study will be useful to understand the neural mechanisms underlying the body color change depending on the ocular system. We also discussed the putative role(s) of opsin-type photoreceptive molecules in the light-induced body color change of the larval zebrafish.",{"EN":187},"Light-induced body color change in developing zebrafish",{"VOID":189},"[\"4232182877744348011\"]",{"VOID":191},"10.1039\u002Fc0pp00199f","PUBLICATION","VERIFIED","2024-04-29T08:11:38.509+00:00","Auto Verify","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1039\u002Fc0pp00199f",[198,214,229],{"id":199,"sortIndex":21,"researcher":20,"roles":200,"affiliations":202,"properties":211,"displayName":213,"givenName":20,"familyName":20},"4f1c4f96-3410-4505-9147-08edb9556355",[201],"AUTHOR",[203],{"id":204,"sortIndex":21,"affiliation":205,"properties":20},"b16223ea-0357-4c7a-bfcc-d6e92471fa4f",{"id":204,"createTime":20,"updateTime":20,"relativeEntities":206,"slug":20,"properties":207,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":210,"statistic":20},[],{"title":208},{"VI":209},"Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan",[],{"title":212},{"VI":213},"Tomoya Shiraki",{"id":215,"sortIndex":145,"researcher":20,"roles":216,"affiliations":217,"properties":224,"displayName":226,"givenName":20,"familyName":20},"8556ffaf-e442-46ff-96c7-b03182cc1ec0",[201],[218],{"id":204,"sortIndex":21,"affiliation":219,"properties":20},{"id":204,"createTime":20,"updateTime":20,"relativeEntities":220,"slug":20,"properties":221,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":223,"statistic":20},[],{"title":222},{"VI":209},[],{"title":225,"gsAuthor":227},{"VI":226},"Daisuke Kojima",{"VOID":228},"[\"AIrGqG0AAAAJ\"]",{"id":230,"sortIndex":231,"researcher":20,"roles":232,"affiliations":233,"properties":240,"displayName":242,"givenName":20,"familyName":20},"7f02c165-6fdc-4502-bc67-2b3056a5a23c",2,[201],[234],{"id":204,"sortIndex":21,"affiliation":235,"properties":20},{"id":204,"createTime":20,"updateTime":20,"relativeEntities":236,"slug":20,"properties":237,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":239,"statistic":20},[],{"title":238},{"VI":209},[],{"title":241,"gsAuthor":243},{"VI":242},"Yoshitaka Fukada",{"VOID":244},"[\"U8-epAUAAAAJ\"]","ARTICLE",{"url":196,"publisher":247,"properties":288},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":248,"slug":10,"properties":249,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":252,"manageAffiliations":257,"indexDatabases":268,"url":20,"thumbnailPath":20,"statistic":283,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":250,"title":251},{"VOID":13},{"EN":15},[253],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":254,"label":255,"description":256,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[258,263],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":259,"slug":20,"properties":260,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":262,"statistic":20},[],{"title":261},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":264,"slug":20,"properties":265,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":267,"statistic":20},[],{"title":266},{"EN":43},[37],[269,276],{"id":47,"indexDatabase":270,"url":58,"indexYears":59,"academicFieldIds":275,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":271,"label":272,"description":273,"key":55,"publicationTags":274,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":277,"url":77,"indexYears":20,"academicFieldIds":282,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":278,"label":279,"description":280,"key":73,"publicationTags":281,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":284,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":285,"totalCitation":121,"totalCitationByYear":286,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":287,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"pages":289,"volume":291},{"VOID":290},"1498-1504",{"VOID":292},"9",71,{"total":293,"publishYear":295,"statisticByYear":296},2010,{},"2010-11-01","ERROR_IN_ANALYZE_CITATION",[62,75],[301,304,310,316,319,322,325,328,331,334,337,340,343,346,349,352,355,358,361,364,367,370,373,376,379,382,385,388,391,397,400,403,406,409],{"id":20,"text":302,"url":20,"identifiers":303},"J. T. Bagnara and M. E. Hadley, Chromatophores and Color Change, Prentice-Hall, Englewood Cliffs, NJ, 1973.",{},{"id":305,"text":306,"url":307,"identifiers":308},"4c68646b-0035-4279-8000-0006b275d4fa","R. Fujii, The Regulation of Motile Activity in Fish Chromatophores, Pigm. Cell Res., 2000, 13, 300–319.","https:\u002F\u002Flink.springer.com\u002F10.1007\u002Fs10440-022-00541-7",{"doi":309},"10.1007\u002Fs10440-022-00541-7",{"id":311,"text":312,"url":313,"identifiers":314},"c2317fc3-f579-42fe-afd2-66d590c82326","K. von Frisch, Beiträge Zur Physiologie Der Pigmentzellen in Der Fischhaut, Pfluegers Arch., 1911, 138, 319–387.","http:\u002F\u002Flink.springer.com\u002F10.1007\u002FBF01680752",{"doi":315},"10.1007\u002FBF01680752",{"id":305,"text":317,"url":307,"identifiers":318},"M. A. Hafeez, W. B. Quay, The Role of Pineal Organ in the Control of Phototaxis and Body Coloration in Rainbow Trout (Salmo gairdneri, Richardson), Z. vergl. Physiologie., 1970, 68, 403–416.",{"doi":309},{"id":20,"text":320,"url":20,"identifiers":321},"L. H. Kleinholz, Studies in Reptilian Colour Changes II. The Pituitary and Adrenal Glands in the Regulation of the Melanophores of Anolis carolinensis, J. Exp. Biol., 1938, 15, 474–491.",{},{"id":305,"text":323,"url":307,"identifiers":324},"H. Laurens, The Reactions of Normal and Eyeless Amphibian Larvae to Light, J. Exp. Zool., 1914, 16, 195–210.",{"doi":309},{"id":20,"text":326,"url":20,"identifiers":327},"A. Amsterdam, N. Hopkins, Mutagenesis Strategies in Zebrafish for Identifying Genes Involved in Development and Disease, Trends Genet., 2006, 22, 473–478.",{},{"id":305,"text":329,"url":307,"identifiers":330},"S. C. F. Neuhauss, O. Biehlmaier, M. W. Seeliger, T. Das, K. Kohler, W. A. Harris, H. Baier, Genetic Disorders of Vision Revealed by a Behavioral Screen of 400 Essential Loci in Zebrafish, J. Neurosci., 1999, 19, 8603–8615.",{"doi":309},{"id":20,"text":332,"url":20,"identifiers":333},"A. Muto, M. B. Orger, A. M. Wehman, M. C. Smear, J. N. Kay, P. S. Page-McCaw, E. Gahtan, T. Xiao, L. M. Nevin, N. J. Gosse, W. Staub, K. Finger-Baier, H. Baier, Forward Genetic Analysis of Visual Behavior in Zebrafish, PLoS Genet., 2005, 1, e66.",{},{"id":20,"text":335,"url":20,"identifiers":336},"B. R. Bill, A. M. Petzold, K. J. Clark, L. A. Schimmenti, S. C. Ekker, A Primer for Morpholino Use in Zebrafish, Zebrafish, 2009, 6, 69–77.",{},{"id":305,"text":338,"url":307,"identifiers":339},"D. W. Logan, S. F. Burn, I. J. Jackson, Regulation of Pigmentation in Zebrafish Melanophores, Pigm. Cell Res., 2006, 19, 206–213.",{"doi":309},{"id":305,"text":341,"url":307,"identifiers":342},"R. N. Kelsh, Genetics and Evolution of Pigment Patterns in Fish, Pigm. Cell Res., 2004, 17, 326–336.",{"doi":309},{"id":20,"text":344,"url":20,"identifiers":345},"M. J. Gentle, The Central Nervous Control of Colour Change in the Minnow (Phoxinus Phoxinus L.). I. Blinding and the Effects of Tectal Removal on Normal and Blind Fish, J. Exp. Biol., 1971, 54, 83–91.",{},{"id":20,"text":347,"url":20,"identifiers":348},"V. C. Fleisch, S. C. Neuhauss, Visual Behavior in Zebrafish, Zebrafish, 2006, 3, 191–201.",{},{"id":20,"text":350,"url":20,"identifiers":351},"F. Duspiva, Beitrage Zur Physiologie Der Melanophoren Von Fischembryonen, Sitzungsber. Akad. Wiss. Wien, Math-Naturwiss. KI., 1, 1931, 140, 553–596.",{},{"id":20,"text":353,"url":20,"identifiers":354},"G. Tomita, Melanophore Reactions to Light During the Early Stages of the Paradise Fish Macropodus Opercularis, J. Shanghai Sci. Inst. IV, 1936, 2, 237–264.",{},{"id":305,"text":356,"url":307,"identifiers":357},"T. Ohta, K. Muramatsu, Spectral Sensitivity of Melanophores in the Primary Color Response of the Rose Bitterling Rhodeus Ocellatus Ocellatus, Jpn. J. Ichthyol., 1988, 34, 483–487.",{"doi":309},{"id":305,"text":359,"url":307,"identifiers":360},"E. Babak, Zur Chromatischen Hautfunktion Der Amphibien, Pfluegers Arch., 1910, 131, 87–118.",{"doi":309},{"id":305,"text":362,"url":307,"identifiers":363},"K. D. Malloy, M. A. Holman, D. Mitchell, H. W. Detrich, Solar UVB-Induced DNA Damage and Photoenzymatic DNA Repair in Antarctic Zooplankton, Proc. Natl. Acad. Sci. U. S. A., 1997, 94, 1258–1263.",{"doi":309},{"id":305,"text":365,"url":307,"identifiers":366},"C. A. Stuermer, Retinotopic Organization of the Developing Retinotectal Projection in the Zebrafish Embryo, J. Neurosci., 1988, 8, 4513–4530.",{"doi":309},{"id":305,"text":368,"url":307,"identifiers":369},"N. Oshima, Direct Reception of Light by Chromatophores of Lower Vertebrates, Pigm. Cell Res., 2001, 14, 312–319.",{"doi":309},{"id":305,"text":371,"url":307,"identifiers":372},"J. N. Lythgoe, J. Shand, R. G. Foster, Visual Pigment in Fish Iridocytes, Nature, 1984, 308, 83–84.",{"doi":309},{"id":305,"text":374,"url":307,"identifiers":375},"A. Daniolos, A. B. Lerner, M. R. Lerner, Action of Light on Frog Pigment Cells in Culture, Pigm. Cell Res., 1990, 3, 38–43.",{"doi":309},{"id":305,"text":377,"url":307,"identifiers":378},"M. D. Rollag, Amphibian Melanophores Become Photosensitive When Treated with Retinal, J. Exp. Zool., 1996, 275, 20–26.",{"doi":309},{"id":20,"text":380,"url":20,"identifiers":381},"I. Provencio, G. S. Jiang, W. J. De Grip, W. P. Hayes, M. D. Rollag, Melanopsin: An Opsin in Melanophores, Brain, and Eye, Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 340–345.",{},{"id":305,"text":383,"url":307,"identifiers":384},"M. C. Isoldi, M. D. Rollag, A. M. D. Castrucci, I. Provencio, Rhabdomeric Phototransduction Initiated by the Vertebrate Photopigment Melanopsin, Proc. Natl. Acad. Sci. U. S. A., 2005, 102, 1217–1221.",{"doi":309},{"id":305,"text":386,"url":307,"identifiers":387},"M. Koyanagi, K. Kubokawa, H. Tsukamoto, Y. Shichida, A. Terakita, Cephalochordate Melanopsin: Evolutionary Linkage between Invertebrate Visual Cells and Vertebrate Photosensitive Retinal Ganglion Cells, Curr. Biol., 2005, 15, 1065–1069.",{"doi":309},{"id":20,"text":389,"url":20,"identifiers":390},"M. Torii, D. Kojima, T. Okano, A. Nakamura, A. Terakita, Y. Shichida, A. Wada, Y. Fukada, Two Isoforms of Chicken Melanopsins Show Blue Light Sensitivity, FEBS Lett., 2007, 581, 5327–5331.",{},{"id":392,"text":393,"url":394,"identifiers":395},"4e57943e-c6d4-4185-8dec-496e3a98b8dd","N. Cermakian, M. P. Pando, C. L. Thompson, A. B. Pinchak, C. P. Selby, L. Gutierrez, D. E. Wells, G. M. Cahill, A. Sancar, P. Sassone-Corsi, Light Induction of a Vertebrate Clock Gene Involves Signaling through Blue-Light Receptors and Map Kinases, Curr. Biol., 2002, 12, 844–848.","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0960982202008357",{"doi":396},"10.1016\u002FS0960-9822(02)00835-7",{"id":305,"text":398,"url":307,"identifiers":399},"D. Kojima, H. Mano, Y. Fukada, Vertebrate Ancient-Long Opsin: A Green-Sensitive Photoreceptive Molecule Present in Zebrafish Deep Brain and Retinal Horizontal Cells, J. Neurosci., 2000, 20, 2845–2851.",{"doi":309},{"id":305,"text":401,"url":307,"identifiers":402},"D. Kojima, M. Torii, Y. Fukada, J. E. Dowling, Differential Expression of Duplicated VAL-Opsin Genes in the Developing Zebrafish, J. Neurochem., 2008, 104, 1364–1371.",{"doi":309},{"id":20,"text":404,"url":20,"identifiers":405},"J. Bellingham, D. Whitmore, A. R. Philp, D. J. Wells, R. G. Foster, Zebrafish Melanopsin: Isolation, Tissue Localisation and Phylogenetic Position, Mol. Brain Res., 2002, 107, 128–136.",{},{"id":20,"text":407,"url":20,"identifiers":408},"H. Mano, D. Kojima, Y. Fukada, Exo-Rhodopsin: A Novel Rhodopsin Expressed in the Zebrafish Pineal Gland, Mol. Brain Res., 1999, 73, 110–118.",{},{"id":305,"text":410,"url":307,"identifiers":411},"P. Moutsaki, D. Whitmore, J. Bellingham, K. Sakamoto, Z. K. David-Gray, R. G. Foster, Teleost Multiple Tissue (Tmt) Opsin: A Candidate Photopigment Regulating the Peripheral Clocks of Zebrafish?, Mol. Brain Res., 2003, 112, 135–145.",{"doi":309},false,{"id":414,"createTime":415,"updateTime":416,"relativeEntities":417,"slug":418,"properties":419,"entityType":192,"verifyStatus":193,"verifyTime":428,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":429,"fullTextUrl":20,"authors":430,"publicationType":245,"publisherRelationship":490,"citationCount":21,"citationInfo":537,"publishDate":540,"publishYear":538,"citationAnalyzeStatus":298,"lastCitationAnalyze":541,"indexDatabases":542,"openAccess":20,"references":543,"isForceReanalyzing":412},"047fe780-a18e-4872-8044-ff8f0e80733f","2023-12-30T21:22:20.444+00:00","2026-08-13T22:01:39.246+00:00",[],"Adjuvant-treatment-for-complement-activation-increases-the-effectiveness-of-photodynamic-therapy-of-solid-tumors",{"abstract":420,"title":422,"gsPaper":424,"doi":426},{"EN":421},"Phototoxic lesions generated in tumor tissue by photodynamic therapy (PDT) are recognized by the host as a threat to the integrity and homeostasis at the affected site. Among the canonical pathways invoked by the host for dealing with this type of challenge is the activation of the complement system, integrating proteins that serve as molecular sensors of danger signals produced by PDT and those initiating signalling cascades coupled into the network of inflammatory and immune responses. Since the activated complement system is a salient participant of the antitumor response produced by PDT, it is worth exploring whether its manipulation can be exploited for the therapeutic benefit. Using mouse tumor models, the present study examined the potential of representative complement-activating agents to act as effective adjuvants to PDT. Tumor-localized treatment with zymosan, an alternative complement pathway activator, reduced the recurrence-rate of PDT-treated tumors, markedly increasing the percentage of permanent cures. In contrast, a similar treatment with heat aggregated gamma globulin (complement activator via the classical pathway) was of no significant benefit as a PDT adjuvant. Systemic complement activation with streptokinase treatment had no detectable effect on complement deposition at the tumor site without PDT, but it augmented the extent of complement activity in PDT-treated tumors. This finding based on immunohistochemistry analysis explains the results of tumor therapy experiments, which showed that systemic treatment with streptokinase or a similar agent, urokinase, enhances the PDT-mediated tumor response. Zymosan and streptokinase administrations produced no beneficial results with PDT of tumors growing in complement-deficient mice. This study, therefore, establishes the potential of complement-activating agents to serve as effective adjuvants to PDT for cancer treatment.",{"EN":423},"Adjuvant treatment for complement activation increases the effectiveness of photodynamic therapy of solid tumors",{"VOID":425},"[\"3942258674104776317\"]",{"VOID":427},"10.1039\u002Fb315663J","2024-05-01T01:05:44.327+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1039\u002Fb315663J",[431,446,459,472],{"id":432,"sortIndex":21,"researcher":20,"roles":433,"affiliations":434,"properties":443,"displayName":445,"givenName":20,"familyName":20},"19b3c9b3-8bcf-4e99-8cde-460f82a7351e",[201],[435],{"id":436,"sortIndex":21,"affiliation":437,"properties":20},"c91c5c4e-4058-49ee-824e-8ffde37fe0db",{"id":436,"createTime":20,"updateTime":20,"relativeEntities":438,"slug":20,"properties":439,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":442,"statistic":20},[],{"title":440},{"VI":441},"British Columbia Cancer Agency, Vancouver, Canada",[],{"title":444},{"VI":445},"Mladen Korbelik",{"id":447,"sortIndex":145,"researcher":20,"roles":448,"affiliations":449,"properties":456,"displayName":458,"givenName":20,"familyName":20},"3f8322f0-cff9-4401-b7b4-12a7c7fe8043",[201],[450],{"id":436,"sortIndex":21,"affiliation":451,"properties":20},{"id":436,"createTime":20,"updateTime":20,"relativeEntities":452,"slug":20,"properties":453,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":455,"statistic":20},[],{"title":454},{"VI":441},[],{"title":457},{"VI":458},"Jinghai Sun",{"id":460,"sortIndex":231,"researcher":20,"roles":461,"affiliations":462,"properties":469,"displayName":471,"givenName":20,"familyName":20},"46b1ed4a-f560-4dca-9773-3fee36ed5c50",[201],[463],{"id":436,"sortIndex":21,"affiliation":464,"properties":20},{"id":436,"createTime":20,"updateTime":20,"relativeEntities":465,"slug":20,"properties":466,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":468,"statistic":20},[],{"title":467},{"VI":441},[],{"title":470},{"VI":471},"Ivana Cecic",{"id":473,"sortIndex":474,"researcher":20,"roles":475,"affiliations":476,"properties":485,"displayName":487,"givenName":20,"familyName":20},"2e91d84e-d7f6-470b-a0ad-e765df203ca0",3,[201],[477],{"id":478,"sortIndex":21,"affiliation":479,"properties":20},"cfbb5e6f-d4ec-4952-bb18-95315f7fffa6",{"id":478,"createTime":20,"updateTime":20,"relativeEntities":480,"slug":20,"properties":481,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":484,"statistic":20},[],{"title":482},{"VI":483},"Canadian Blood Services, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada",[],{"title":486,"gsAuthor":488},{"VI":487},"Katherine Serrano",{"VOID":489},"[\"EvHMiKUAAAAJ\"]",{"url":429,"publisher":491,"properties":532},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":492,"slug":10,"properties":493,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":496,"manageAffiliations":501,"indexDatabases":512,"url":20,"thumbnailPath":20,"statistic":527,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":494,"title":495},{"VOID":13},{"EN":15},[497],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":498,"label":499,"description":500,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[502,507],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":503,"slug":20,"properties":504,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":506,"statistic":20},[],{"title":505},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":508,"slug":20,"properties":509,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":511,"statistic":20},[],{"title":510},{"EN":43},[37],[513,520],{"id":47,"indexDatabase":514,"url":58,"indexYears":59,"academicFieldIds":519,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":515,"label":516,"description":517,"key":55,"publicationTags":518,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":521,"url":77,"indexYears":20,"academicFieldIds":526,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":522,"label":523,"description":524,"key":73,"publicationTags":525,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":528,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":529,"totalCitation":121,"totalCitationByYear":530,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":531,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"pages":533,"volume":535},{"VOID":534},"812-816",{"VOID":536},"3",{"total":21,"publishYear":538,"statisticByYear":539},2004,{},"2004-08-01","2026-08-13T22:01:39.245+00:00",[62,75],[544,547,550,553,556,562,565,568,571,574,577,580,583,586,589,592,595,598,601,604,607,610],{"id":20,"text":545,"url":20,"identifiers":546},"T. J. Dougherty, C. J. Gomer, B. W. Henderson, G. Jori, D. Kessel, M. Korbelik, J. Moan and Q., Peng, Photodynamic Therapy J. Natl. Cancer Inst. 1998 90 889–905",{},{"id":20,"text":548,"url":20,"identifiers":549},"I. Cecic, B. Stott, J. Sun and M. Korbelik, Relevance of innate immunity recognition of altered self in the induction of host response associated with photodynamic therapy, in Recent Research Development in Cancer, ed. S. G. Pandalai, Transworld Research Network, Trivandrum, India, vol. 5, in press",{},{"id":20,"text":551,"url":20,"identifiers":552},"M. Korbelik and I., Cecic, Mechanism of tumor destruction by photodynamic therapy, in Handbook of Photochemistry and Photobiology, ed. H. S. Nalwa, American Scientific Publishers, Stevenson Ranch, CA, vol. 4, 2003, pp. 39-77",{},{"id":20,"text":554,"url":20,"identifiers":555},"N. R. Cooper, Biology of the complement system, in Inflammation: Basic Principles and Clinical Correlations, ed. J. I. Galin and R. Snyderman, Lippincott Williams & Wilkins, Philadelphia, PA, 1999, pp. 281-315",{},{"id":557,"text":558,"url":559,"identifiers":560},"d8454e76-0785-4219-a50f-eff1e76bd66c","K. Elward and P., Gasque, “Eat me” and “don’t eat me” signals govern the innate immune response and tissue repair in the CNS; emphasis on the critical role of the complement system Mol. Immunol. 2003 40 85–94","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0161589003001093",{"doi":561},"10.1016\u002FS0161-5890(03)00109-3",{"id":305,"text":563,"url":307,"identifiers":564},"I. Cecic and M., Korbelik, Mediators of peripheral blood neutrophilia induced by photodynamic therapy of solid tumors Cancer Lett. 2002 183 43–51",{"doi":309},{"id":305,"text":566,"url":307,"identifiers":567},"L. Clemenza, F. Dieli, M. Cicardi and A., Salerno, Research on complement: old issues revisited and a novel sphere of influence Trends Immunol. 2003 24 292–295",{"doi":309},{"id":305,"text":569,"url":307,"identifiers":570},"Y. Y. Maeda and G., Chihara, The effects of neonatal thymectomy on the antitumor activity of lentinan, carboxymethylpachymaran and zymosan, and their effects on various immune rsponses Int. J. Cancer 1973 11 153–161",{"doi":309},{"id":305,"text":572,"url":307,"identifiers":573},"P. D., Cooper, Solid phase activators of the alternative pathway of complement and their use in vivo, in Activators and Inhibitors of Complement, ed. R. B. Sim, Kluwer Academic Publishers, Amsterdam, 1993, pp. 69-106",{"doi":309},{"id":305,"text":575,"url":307,"identifiers":576},"W. T. Bradner, D. A. Clarke and C. C., Stock, Stimulation of host defense against experimental cancer. I. Zymosan and sarcoma 180 in mice Cancer Res. 1958 18 347–351",{"doi":309},{"id":305,"text":578,"url":307,"identifiers":579},"T. J. H. Volman, R. J. A. Goris, M. van der Jagt, F. A. J. van de Loo and T., Hendriks, Organ damage in zymosan-induced multiple organ dysfunction syndrome in mice is not mediated by inducible nitric oxide synthase Crit. Care Med. 2002 30 1553–1559",{"doi":309},{"id":305,"text":581,"url":307,"identifiers":582},"S. Oren, I. Maslovsky, M. Schlesinger and L., Resin, Complement activation in patients with acute myocardial infarction treated with streptokinase Am. J. Med. Sci. 1998 315 24–29",{"doi":309},{"id":305,"text":584,"url":307,"identifiers":585},"G. A. Ewald and P. R., Eisenberg, Plasmin-mediated activation of contact system in response to pharmacological thrombolysis Circulation 1995 91 28–36",{"doi":309},{"id":305,"text":587,"url":307,"identifiers":588},"M. Korbelik and G., Krosl, Photofrin accumulation in malignant and host cell populations of various tumours Br. J. Cancer 1996 73 506–513",{"doi":309},{"id":305,"text":590,"url":307,"identifiers":591},"J. Sun, I. Cecic, C. S. Parkins and M., Korbelik, Neutrophils as inflammatory and immune effectors in photodynamic therapy-treated mouse SCCVII tumors Photochem. Photobiol. Sci. 2002 1 690–695",{"doi":309},{"id":305,"text":593,"url":307,"identifiers":594},"Y. S. Taktak and B., Stenning, Solid pahse enzyme immunoassay for the quantification of serum amyloid P (SAP) and complement component 3 (C3) proteins in acute-phase mouse sera Horm. Metab. Res. 1992 24 371–374",{"doi":309},{"id":305,"text":596,"url":307,"identifiers":597},"M. I. Gyongyossy and S. N., Assimeth, Isolation of the third component of mouse complement J. Immunol. 1977 118 1032–1035",{"doi":309},{"id":305,"text":599,"url":307,"identifiers":600},"H.-P. T. Ekre, B. Fjellner and Ö. Hägermark Inhibition of complement dependent experimental inflammation in human skin by different heparin fractions Int. J. Immunopharmacol. 1986 8 277–286",{"doi":309},{"id":305,"text":602,"url":307,"identifiers":603},"L. D. Shultz, P. A. Schwietzer, S. W. Christianson, B. Gott, I. B. Schweitzer, B. Tennant, S. McKenna, L. Mobraaten, T. V. Rajan, D. L. Greiner and E. H., Leiter, Multiple defects in innate and adaptive immunological function in NOD\u002FLtz-scid mice J. Immunol. 1995 154 180–191",{"doi":309},{"id":305,"text":605,"url":307,"identifiers":606},"W. T. Schaiff and P. R., Eisenberg, Direct induction of complement activation by pharmacologic activation of plasminogen Coron. Artery Dis. 1997 8 9–18",{"doi":309},{"id":305,"text":608,"url":307,"identifiers":609},"I. Cecic, C. S. Parkins and M., Korbelik, Induction of systemic neutrophil response in mice by photodynamic therapy of solid tumors Photochem. Photobiol. 2001 74 712–720",{"doi":309},{"id":20,"text":611,"url":20,"identifiers":612},"I. Cecic and M. Korbelik, unpublished",{},{"id":614,"createTime":615,"updateTime":616,"relativeEntities":617,"slug":618,"properties":619,"entityType":192,"verifyStatus":193,"verifyTime":632,"verifyNote":195,"languages":633,"translateLanguages":20,"viewCount":21,"primaryUrl":635,"fullTextUrl":20,"authors":636,"publicationType":245,"publisherRelationship":677,"citationCount":21,"citationInfo":726,"publishDate":729,"publishYear":727,"citationAnalyzeStatus":19,"lastCitationAnalyze":616,"indexDatabases":730,"openAccess":20,"references":731,"isForceReanalyzing":412},"bdd3836b-603a-423b-80f9-cb18d445d143","2024-04-18T19:59:57.638+00:00","2026-07-26T21:04:45.560+00:00",[],"Photofunctional-proteins-how-nature-keeps-the-laboratories-updated-about-light-and-life",{"openalex":620,"mag":622,"title":624,"gsPaper":626,"pm":628,"doi":630},{"VOID":621},"W2144366296",{"VOID":623},"2144366296",{"EN":625},"Photofunctional proteins: how nature keeps the laboratories updated about light and life",{"VOID":627},"[\"10124869266039794118\"]",{"VOID":629},"25625468",{"VOID":631},"10.1039\u002Fc5pp90004b","2024-05-14T09:00:53.600+00:00",[634],"EN","https:\u002F\u002Flink.springer.com\u002F10.1039\u002Fc5pp90004b",[637,658],{"id":638,"sortIndex":21,"researcher":20,"roles":639,"affiliations":640,"properties":649,"displayName":653,"givenName":20,"familyName":20},"2fe6d02d-c710-4dd5-a089-943231c832c6",[],[641],{"id":642,"sortIndex":21,"affiliation":643,"properties":20},"768bcc2d-a514-4a1f-aaa3-27a03da68db0",{"id":642,"createTime":20,"updateTime":20,"relativeEntities":644,"slug":20,"properties":645,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":648,"statistic":20},[],{"title":646},{"VI":647},"Department of Physics and Earth Sciences, University of Parma, Parma, Italy",[],{"orcid":650,"title":652,"gsAuthor":654,"openalex":656},{"VOID":651},"https:\u002F\u002Forcid.org\u002F0000-0003-0497-2723",{"EN":653},"Aba Losi",{"VOID":655},"[\"r0xbsPEAAAAJ\"]",{"VOID":657},"A5036968154",{"id":659,"sortIndex":145,"researcher":20,"roles":660,"affiliations":661,"properties":670,"displayName":674,"givenName":20,"familyName":20},"97f6892b-4c28-4c78-9ea0-ec0e83d2437c",[],[662],{"id":663,"sortIndex":21,"affiliation":664,"properties":20},"176fa5b8-6b2e-4f27-991f-74228cc6a913",{"id":663,"createTime":20,"updateTime":20,"relativeEntities":665,"slug":20,"properties":666,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":669,"statistic":20},[],{"title":667},{"VI":668},"Department of Life Sciences, University of Parma, Parma, Italy",[],{"orcid":671,"title":673,"openalex":675},{"VOID":672},"https:\u002F\u002Forcid.org\u002F0000-0001-7685-8554",{"EN":674},"Stefania Abbruzzetti",{"VOID":676},"A5046034242",{"url":20,"publisher":678,"properties":719},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":679,"slug":10,"properties":680,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":683,"manageAffiliations":688,"indexDatabases":699,"url":20,"thumbnailPath":20,"statistic":714,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":681,"title":682},{"VOID":13},{"EN":15},[684],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":685,"label":686,"description":687,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[689,694],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":690,"slug":20,"properties":691,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":693,"statistic":20},[],{"title":692},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":695,"slug":20,"properties":696,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":698,"statistic":20},[],{"title":697},{"EN":43},[37],[700,707],{"id":47,"indexDatabase":701,"url":58,"indexYears":59,"academicFieldIds":706,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":702,"label":703,"description":704,"key":55,"publicationTags":705,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":708,"url":77,"indexYears":20,"academicFieldIds":713,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":709,"label":710,"description":711,"key":73,"publicationTags":712,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":715,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":716,"totalCitation":121,"totalCitationByYear":717,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":718,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"issue":720,"pages":722,"volume":724},{"VOID":721},"2",{"VOID":723},"198-199",{"VOID":725},"14",{"total":21,"publishYear":727,"statisticByYear":728},2015,{},"2015-02-01",[62,75],[],{"id":733,"createTime":734,"updateTime":735,"relativeEntities":736,"slug":737,"properties":738,"entityType":192,"verifyStatus":193,"verifyTime":749,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":750,"fullTextUrl":20,"authors":751,"publicationType":245,"publisherRelationship":795,"citationCount":21,"citationInfo":842,"publishDate":845,"publishYear":843,"citationAnalyzeStatus":19,"lastCitationAnalyze":846,"indexDatabases":847,"openAccess":20,"references":20,"isForceReanalyzing":412},"102aa0e0-40e2-43a4-80c0-001f26b0e25f","2023-12-31T09:25:30.551+00:00","2026-07-23T13:53:01.261+00:00",[],"Solar-UV-exposure-of-primary-schoolchildren-in-Valencia-Spain",{"abstract":739,"title":741,"gsPaper":743,"references":745,"doi":747},{"EN":740},"To quantify schoolchildren’s exposure to ultraviolet erythemal radiation (UVER), personal dosimeters (VioSpor) were used to measure biologically effective ultraviolet (UV) radiation received in the course of their daily school activities. The study took place in two primary schools in Valencia (39°28′N), Spain, for several weeks from March 2008 until May 2009, with two age groups (6-8 years and 10-11 years) and involved about 47 schoolchildren. The median daily UV exposure values for all age groups and solar height intervals considered in the study ranged from 1.31 to 2.11 standard erythemal doses (SEDs). Individual UV exposure was analyzed as a function of age, gender and dosimeter position. Significant statistical differences were found between different age groups, with the younger age group receiving higher statistically significant UVER exposure. It was also found that boys received significantly higher UVER exposure than girls. It was also noted that shoulder dosimeters registered higher readings than wrist dosimeters. Exposure ratio (ER) is defined as the ratio between the personal dose on a selected anatomical site and the corresponding ambient dose on a horizontal plane. The median ER for all age groups and solar height intervals in the study range from 4.5% to 10.7%, with higher values at lower solar heights.",{"EN":742},"Solar UV exposure of primary schoolchildren in Valencia, Spain",{"VOID":744},"[\"9833215405318350376\"]",{"VOID":746},"IARC, IARC monographs on the evaluation of carcinogenic risks to humans: solar and ultraviolet radiation, Lyon, 2000, 55.\nB. K. Armstrong and A. Kricker, The epidemiology of UV induced skin cancer, J. Photochem. Photobiol., B, 2001, 63, 8–18.\nB. Armstrong, How sun exposure causes skin cancer: an epidemiological perspective, In Prevention of Skin Cancer, ed by D. Hill, J. M. Elwood and D. R. English, Kluwer Academic, 2005, pp. 89–116.\nA. Østerlind, M. A. Tucker, B. J. Stone and O. M. Jensen, The Danish Case Control Study of cutaneous malignant melanoma. II. Importance of UV-light exposure, Int. J. Cancer, 1988, 42, 319–324.\nM. A. Weinstock, G. A. Colditz, W. C. Willet, M. J. Stampfer, B. R. Bronstein, M. C. Mihm, Jr. and F. E. Speizer, Non-familial cutaneous melanoma incidence in women associated with sun exposure before 20 years of age, Pediatrics, 1989, 84, 199–204.\nS. A. Oliveria, M. Saraiya, A. C. Geller, M. K. Heneghan and C. Jorgensen, Sun exposure and risk of melanoma, Arch. Dis. Child., 2005, 91, 131–138.\nM. Saraiya, K. Glanz, P. A. Briss, P. Nichols, C. White, D. Das, S. J. Smith, B. Tannor, A. B. Hutchinson, K. M. Wilson, N. Ghandi, N. C. Lee, B. Rimer, R. C. Coates, J. F. Kerner, R. A. Hiatt, P. Buffler and P. Rochester, Interventions to prevent skin cancer by reducing exposure to ultraviolet radiation: a systematic review, Am. J. Prev. Med., 2004, 27, 422–466.\nC. Wright and A. Reeder, Youth solar ultraviolet radiation exposure, concurrent activities and sun-protective practices: A review, Photochem. Photobiol., 2005, 81, 1331–1342.\nC. Y. Guy, R. D. Diab and B. M. Martincigh, Ultraviolet radiation exposure of children and adolescents in Durban, South Africa, Photochem. Photobiol., 2003, 77, 265–270.\nB. L. Diffey, C. J. Gibson, R. Haylock and A. F. McKinlay, Outdoor ultraviolet exposure of children and adolescents, Br. J. Dermatol., 1996, 134, 1030–1034.\nM. Kimlin and A. Parisi, Usage of real-time ultraviolet radiation data to modify the daily erythemal exposure of primary schoolchildren, Photodermatol., Photoimmunol. Photomed., 2001, 17, 130–135.\nP. Gies, C. Roy, S. Toomey, R. MacLennan and M. Watson, Solar UVR exposures of primary schoolchildren at three locations in Queensland, Photochem. Photobiol., 1998, 68, 78–83.\nC. Y. Wright, A. I. Reeder, G. E. Bodeker, A. Gray and B. Cox, Solar UVR exposure, concurrent activities and sun-protective practices among primary schoolchildren, Photochem. Photobiol., 2007, 83, 749–758.\nM. Ono, N. Munakata and S. Watanabe, UV exposure of elementary school children in five Japanese cities, Photochem. Photobiol., 2005, 81, 437–445.\nE. P. Thieden, A. Philipsen, J. Heydenreich and H. C. Wulf, UV radiation exposure related to age, sex, occupation, and sun behaviour based on time-stamped personal dosimeter readings, Arch. Dermatol., 2004, 140, 197–203.\nC. Boldeman, H. Dal and U. Wester, Swedish pre-school children’s UVR exposure - a comparison between two outdoor environments, Photodermatol., Photoimmunol. Photomed., 2004, 20, 2–8.\nM. Norval, A. P. Cullen, F. R. de Gruijl, J. Longstreth, Y. Takizawa, R. M. Lucas, F. P. Noonan and J. C. Van Der Leun, The effects on human health from stratospheric ozone depletion and its interactions with climate change, Photochem. Photobiol. Sci., 2007, 6, 232–251.\nW. B. Grant and M. F. Holick, Benefits and requirements of vitamin D for optimal health: a review, Altern. Med. Rev., 2005, 10(2), 94–104.\nM. Moehrle, M. Korn and C. Garbe, Bacillus subtilis spore film dosimeters in personal dosimetry for occupational solar ultraviolet exposure, Int. Arch. Occup. Environ. Health, 2003, 173, 575–580.\nM. Moehrle, B. Dennenmoser and C. Garbe, Continuous long-term monitoring of UV radiation in Professional mountain guides reveals extremely high exposure, Int. J. Cancer, 2003, 103, 775–778.\nM. Moehrle and C. Garbe, Personal UV dosymetry by Bacillus subtilis Spore Films, Dermatology, 2000, 200, 1–5.\nM. Moehrle, L. Heinrich, A. Schmid and C. Garbe, Extreme UV exposure of professional Cyclists, Dermatology, 2000, 201, 44–45.\nM. Moehrle, Ultraviolet exposure in the Ironman triathlon, Off. J. Am. Coll. Sports Med., 2000, 33(8), 1385–1386.\nE. Thieden, M. S. A°gren and H. C. Wulf, The wrist is a reliable body site for personal dosimetry of ultraviolet radiation, Photodermatol., Photoimmunol. Photomed., 2000, 16, 57–61.\nN. Munakata, M. Ono and S. Watanabe, Monitoring of Solar-UV Exposure among Schoolchildren in Five Japanese Cities using Spore Dosimeter and UV-coloring Labels, Jpn. J. Cancer Res., 1998, 89, 235–245.\nT. B. Fitzpatrick, M. Pathak, and J. A. Parrish, Protection of human skin against the effects of the sunburn ultraviolet (290-32.nm), In Sunlight and Man: Normal and Abnormal Photobiologic Responses, ed. by M. A. Pathak, L. C. Harber, M. Seiji and A. Kukita, University of Tokyo Press, Tokyo, 1974, p. 751.\nBiosense Laboratories, available at http:\u002F\u002Fwww.biosense.de\u002Fhomee.htm, accessed on 5 March 2010.\nY. Furusawa, L. E. Quintern, H. Holtschmidt, P. Koepke and M. Saito, Determination of erythema-effective solar radiation in Japan and Germany with a spore monolayer film optimized for the detection of UVA and UVA - results of a field campaign, Appl. Microbiol. Biotechnol., 1998, 50, 597–603.\nA. F. McKinlay and B. L. Diffey, A reference action spectrum for ultraviolet induced erythema in human skin, CIE Journal, 1987, 6, 17–22.\nThe International Commission on Illumination, Standard Erythema Dose, a Review, CIE J., 1997, 125.\nPrograma meteorología de la Fundación Centro de Estudios Ambientales del Mediterráneo (Generalitat Valenciana), available at http:\u002F\u002Fwww.gva.es\u002Fceamet\u002Fvigilancia\u002FradUV\u002FradUV.html, accessed on 10 March 2010.\nAgencia Estatal de Meteorología, available at http:\u002F\u002Fwww.aemet.es\u002F, accessed on 10 March 2010.\nNASA, Total Ozone Mapping Spectrometer, available at http:\u002F\u002Fjwocky.gsfc.nasa.gov\u002F, accessed on 10 March 2010.\nWorld Health Organization, Global Solar UV Index: A Practical guide, WHO, Geneva, Switzerland, 2002.\nInternational Commission on Non-Ionizing Radiation Protection, Global Solar UV Index, ICNIRP-1\u002F95, 1995.\nE. Herlihy, H. P. Gies, C. R. Roy and M. Jones, Personal dosimetry of solar UVR for different outdoor activities, Photochem. Photobiol., 1994, 60, 288–294.\nC. D. J. Holman, I. M. Gibson, M. Stephenson and B. K. Armstrong, Ultraviolet irradiation of human body sites in relation to occupation and outdoor activity: field studies using personal UVR dosimeters, Clin. Exp. Dermatol., 1983, 8, 269–277.",{"VOID":748},"10.1039\u002Fc0pp00153h","2024-05-12T22:36:06.363+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1039\u002Fc0pp00153h",[752,767,782],{"id":753,"sortIndex":21,"researcher":20,"roles":754,"affiliations":755,"properties":764,"displayName":766,"givenName":20,"familyName":20},"aedf7a87-3b15-4b3f-864d-14520ed1a53e",[201],[756],{"id":757,"sortIndex":21,"affiliation":758,"properties":20},"7ed44b8b-8bed-4675-a74f-79c29f3a7e98",{"id":757,"createTime":20,"updateTime":20,"relativeEntities":759,"slug":20,"properties":760,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":763,"statistic":20},[],{"title":761},{"VI":762},"Departamento de Física Aplicada, Universidad Politécnica de Valencia, Valencia, Spain",[],{"title":765},{"VI":766},"María-Antonia Serrano",{"id":768,"sortIndex":145,"researcher":20,"roles":769,"affiliations":770,"properties":779,"displayName":781,"givenName":20,"familyName":20},"15bd2356-d0d7-4782-871d-4e9206a72354",[201],[771],{"id":772,"sortIndex":21,"affiliation":773,"properties":20},"cd3ad467-8a02-42eb-ba56-d0bc7ffaa49e",{"id":772,"createTime":20,"updateTime":20,"relativeEntities":774,"slug":20,"properties":775,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":778,"statistic":20},[],{"title":776},{"VI":777},"Departamento de Termodinámica Aplicada, Universidad Politécnica de Valencia, Valencia, Spain",[],{"title":780},{"VI":781},"Javier Cañada",{"id":783,"sortIndex":231,"researcher":20,"roles":784,"affiliations":785,"properties":792,"displayName":794,"givenName":20,"familyName":20},"cb63a544-7bbc-4b65-bbd4-f9f783e5198f",[201],[786],{"id":757,"sortIndex":21,"affiliation":787,"properties":20},{"id":757,"createTime":20,"updateTime":20,"relativeEntities":788,"slug":20,"properties":789,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":791,"statistic":20},[],{"title":790},{"VI":762},[],{"title":793},{"VI":794},"Juan Carlos Moreno",{"url":750,"publisher":796,"properties":837},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":797,"slug":10,"properties":798,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":801,"manageAffiliations":806,"indexDatabases":817,"url":20,"thumbnailPath":20,"statistic":832,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":799,"title":800},{"VOID":13},{"EN":15},[802],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":803,"label":804,"description":805,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[807,812],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":808,"slug":20,"properties":809,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":811,"statistic":20},[],{"title":810},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":813,"slug":20,"properties":814,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":816,"statistic":20},[],{"title":815},{"EN":43},[37],[818,825],{"id":47,"indexDatabase":819,"url":58,"indexYears":59,"academicFieldIds":824,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":820,"label":821,"description":822,"key":55,"publicationTags":823,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":826,"url":77,"indexYears":20,"academicFieldIds":831,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":827,"label":828,"description":829,"key":73,"publicationTags":830,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":833,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":834,"totalCitation":121,"totalCitationByYear":835,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":836,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"pages":838,"volume":840},{"VOID":839},"523-530",{"VOID":841},"10",{"total":21,"publishYear":843,"statisticByYear":844},2020,{},"2020-10-27","2026-07-23T13:53:01.260+00:00",[62,75],{"id":849,"createTime":850,"updateTime":851,"relativeEntities":852,"slug":853,"properties":854,"entityType":192,"verifyStatus":193,"verifyTime":867,"verifyNote":195,"languages":868,"translateLanguages":20,"viewCount":21,"primaryUrl":869,"fullTextUrl":20,"authors":870,"publicationType":245,"publisherRelationship":961,"citationCount":1009,"citationInfo":1010,"publishDate":1014,"publishYear":1011,"citationAnalyzeStatus":1015,"lastCitationAnalyze":1016,"indexDatabases":1017,"openAccess":20,"references":1018,"isForceReanalyzing":412},"92d2717d-34c6-41c7-815b-3e8d1d125299","2024-04-18T03:51:21.486+00:00","2026-07-23T04:47:49.819+00:00",[],"Photophysical-and-photobiological-properties-of-a-sulfonated-chlorin-photosensitiser-TPCS2a-for-photochemical-internalisation-PCI-",{"openalex":855,"mag":857,"title":859,"gsPaper":861,"pm":863,"doi":865},{"VOID":856},"W2115595812",{"VOID":858},"2115595812",{"EN":860},"Photophysical and photobiological properties of a sulfonated chlorin photosensitiser TPCS2a for photochemical internalisation (PCI)",{"VOID":862},"[]",{"VOID":864},"23232550",{"VOID":866},"10.1039\u002Fc2pp25328c","2024-06-25T11:15:57.260+00:00",[634],"https:\u002F\u002Flink.springer.com\u002F10.1039\u002Fc2pp25328c",[871,890,909,926,943],{"id":872,"sortIndex":21,"researcher":20,"roles":873,"affiliations":874,"properties":883,"displayName":887,"givenName":20,"familyName":20},"c880c2ac-2812-473e-8ba5-00f70a7d3ae8",[],[875],{"id":876,"sortIndex":21,"affiliation":877,"properties":20},"ec252b8c-57f6-485f-a790-0b1435614523",{"id":876,"createTime":20,"updateTime":20,"relativeEntities":878,"slug":20,"properties":879,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":882,"statistic":20},[],{"title":880},{"EN":881},"National Medical Laser Centre, Division of Surgery and Interventional Science and Institute for Biomedical Engineering, University College London, 67-73 Riding House Street, London, W1W 7EJ, UK",[],{"orcid":884,"title":886,"openalex":888},{"VOID":885},"https:\u002F\u002Forcid.org\u002F0000-0001-5956-0123",{"EN":887},"Julie Wang",{"VOID":889},"A5031674948",{"id":891,"sortIndex":145,"researcher":20,"roles":892,"affiliations":893,"properties":902,"displayName":906,"givenName":20,"familyName":20},"9f821b70-3ed1-497c-901e-5b9cbbee825c",[],[894],{"id":895,"sortIndex":21,"affiliation":896,"properties":20},"e1e8021a-4bac-4d0f-af1d-4c08c0881eb5",{"id":895,"createTime":20,"updateTime":20,"relativeEntities":897,"slug":20,"properties":898,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":901,"statistic":20},[],{"title":899},{"EN":900},"Deparment of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Norweigian Radium Hospital, N-0310, Montebello, Norway",[],{"orcid":903,"title":905,"openalex":907},{"VOID":904},"https:\u002F\u002Forcid.org\u002F0000-0003-4059-3106",{"EN":906},"Kristian Berg",{"VOID":908},"A5075259826",{"id":910,"sortIndex":231,"researcher":20,"roles":911,"affiliations":912,"properties":921,"displayName":923,"givenName":20,"familyName":20},"0162d861-0ff0-466a-8157-49cbb52169f4",[],[913],{"id":914,"sortIndex":21,"affiliation":915,"properties":20},"13970a99-9435-4f17-94de-9dac817c61ce",{"id":914,"createTime":20,"updateTime":20,"relativeEntities":916,"slug":20,"properties":917,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":920,"statistic":20},[],{"title":918},{"EN":919},"PCI Biotech AS, Strandveien 55, N-1366, Lysaker, Norway",[],{"title":922,"openalex":924},{"EN":923},"Anders Høgset",{"VOID":925},"A5019470770",{"id":927,"sortIndex":474,"researcher":20,"roles":928,"affiliations":929,"properties":936,"displayName":940,"givenName":20,"familyName":20},"ec2fd13b-36e8-4058-a909-d6b685e4def0",[],[930],{"id":876,"sortIndex":21,"affiliation":931,"properties":20},{"id":876,"createTime":20,"updateTime":20,"relativeEntities":932,"slug":20,"properties":933,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":935,"statistic":20},[],{"title":934},{"EN":881},[],{"orcid":937,"title":939,"openalex":941},{"VOID":938},"https:\u002F\u002Forcid.org\u002F0000-0002-5538-9303",{"EN":940},"Stephen G. Bown",{"VOID":942},"A5058433239",{"id":944,"sortIndex":945,"researcher":20,"roles":946,"affiliations":947,"properties":954,"displayName":958,"givenName":20,"familyName":20},"ea310c34-7375-4237-87e0-c839821e4c7b",4,[],[948],{"id":876,"sortIndex":21,"affiliation":949,"properties":20},{"id":876,"createTime":20,"updateTime":20,"relativeEntities":950,"slug":20,"properties":951,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":953,"statistic":20},[],{"title":952},{"EN":881},[],{"orcid":955,"title":957,"openalex":959},{"VOID":956},"https:\u002F\u002Forcid.org\u002F0000-0002-3303-4480",{"EN":958},"Alexander J. MacRobert",{"VOID":960},"A5054270886",{"url":20,"publisher":962,"properties":1003},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":963,"slug":10,"properties":964,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":967,"manageAffiliations":972,"indexDatabases":983,"url":20,"thumbnailPath":20,"statistic":998,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":965,"title":966},{"VOID":13},{"EN":15},[968],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":969,"label":970,"description":971,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[973,978],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":974,"slug":20,"properties":975,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":977,"statistic":20},[],{"title":976},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":979,"slug":20,"properties":980,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":982,"statistic":20},[],{"title":981},{"EN":43},[37],[984,991],{"id":47,"indexDatabase":985,"url":58,"indexYears":59,"academicFieldIds":990,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":986,"label":987,"description":988,"key":55,"publicationTags":989,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":992,"url":77,"indexYears":20,"academicFieldIds":997,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":993,"label":994,"description":995,"key":73,"publicationTags":996,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":999,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":1000,"totalCitation":121,"totalCitationByYear":1001,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":1002,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"issue":1004,"pages":1005,"volume":1007},{"VOID":536},{"VOID":1006},"519-526",{"VOID":1008},"12",23,{"total":1009,"publishYear":1011,"statisticByYear":1012},2013,{"2013":945,"2014":145,"2015":474,"2017":1013,"2018":231,"2019":231,"2020":945},7,"2013-03-01","ERROR_IN_GET_PLATFORM_ID","2026-07-23T04:47:49.818+00:00",[62,75],[1019,1023,1027,1031,1035,1039,1042,1046,1050,1053,1057,1061,1065,1069,1073,1077,1081,1085,1089,1093,1097,1101,1104,1108,1112,1115,1119,1123,1127,1131,1134,1138,1142,1146,1150,1154,1158,1162],{"id":20,"text":1020,"url":20,"identifiers":1021},"P. K. Selbo, A. Weyergang, A. Høgset, O. J. Norum, M. B. Berstad, M. Vikdal, K. Berg, J. Controlled Release, 2010, 148, 2–12.",{"doi":1022},"10.1016\u002Fj.jconrel.2010.06.008",{"id":20,"text":1024,"url":20,"identifiers":1025},"S. B. Brown, E. A. Brown, I. Walker, Lancet Oncol., 2004, 5, 497–6508.",{"doi":1026},"10.1016\u002FS1470-2045(04)01529-3",{"id":20,"text":1028,"url":20,"identifiers":1029},"L. M. Bareford, P. W. Swaan, Adv. Drug Delivery Rev., 2007, 59, 748–758.",{"doi":1030},"10.1016\u002Fj.addr.2007.06.008",{"id":20,"text":1032,"url":20,"identifiers":1033},"K. Berg, J. Moan, Int. J. Cancer, 1994, 59, 814–822.",{"doi":1034},"10.1002\u002Fijc.2910590618",{"id":20,"text":1036,"url":20,"identifiers":1037},"J. Moan, K. Berg, H. Anholt, K. Madslien, Int. J. Cancer, 1994, 58, 865–870.",{"doi":1038},"10.1002\u002Fijc.2910580620",{"id":20,"text":1040,"url":20,"identifiers":1041},"K. Berg, P. K. Selbo, L. Prasmickaite, T. E. Tjelle, K. Sandvig, J. Moan, G. Gaudernack, O. Fodstad, S. Kjolsrud, H. Anholt, G. H. Rodal, S. K. Rodal, A. Høgset, Cancer Res., 1999, 59, 1180–1183.",{},{"id":20,"text":1043,"url":20,"identifiers":1044},"A. Hogset, L. Prasmickaite, P. K. Selbo, M. Hellum, B. O. Engesaeter, A. Bonsted, K. Berg, Adv. Drug Delivery Rev., 2004, 56, 95–115.",{"doi":1045},"10.1016\u002Fj.addr.2003.08.016",{"id":20,"text":1047,"url":20,"identifiers":1048},"O. J. Norum, P. K. Selbo, A. Weyergang, K. E. Giercksky, K. Berg, J. Photochem. Photobiol., B, 2009, 96, 83–92.",{"doi":1049},"10.1016\u002Fj.jphotobiol.2009.04.012",{"id":20,"text":1051,"url":20,"identifiers":1052},"K. Berg, K. Sandvig and J. Moan, Transfer of molecules into the cytosol of cells. [PCT\u002FNO95\u002F00149], 1996.",{},{"id":20,"text":1054,"url":20,"identifiers":1055},"P. K. Selbo, K. Sandvig, V. Kirveliene, K. Berg, Biochim. Biophys. Acta, 2000, 1475, 307–313.",{"doi":1056},"10.1016\u002FS0304-4165(00)00082-9",{"id":20,"text":1058,"url":20,"identifiers":1059},"M. G. Battelli, Mini-Rev. Med. Chem., 2004, 4, 513–521.",{"doi":1060},"10.2174\u002F1389557043403819",{"id":20,"text":1062,"url":20,"identifiers":1063},"P. K. Selbo, G. Sivam, O. Fodstad, K. Sandvig, K. Berg, Int. J. Cancer, 2000, 87, 853–859.",{"doi":1064},"10.1002\u002F1097-0215(20000915)87:6\u003C853::AID-IJC15>3.0.CO;2-0",{"id":20,"text":1066,"url":20,"identifiers":1067},"P. K. Selbo, O. Kaalhus, G. Sivam, K. Berg, Photochem. Photobiol., 2001, 74, 303–310.",{"doi":1068},"10.1562\u002F0031-8655(2001)074\u003C0303:AABPIO>2.0.CO;2",{"id":20,"text":1070,"url":20,"identifiers":1071},"A. Weyergang, P. K. Selbo, K. Berg, J. Controlled Release, 2006, 111, 165–173.",{"doi":1072},"10.1016\u002Fj.jconrel.2005.12.002",{"id":20,"text":1074,"url":20,"identifiers":1075},"W. L. Yip, A. Weyergang, K. Berg, H. H. Tonnesen, P. K. Selbo, Mol. Pharm., 2007, 4, 241–251.",{"doi":1076},"10.1021\u002Fmp060105u",{"id":20,"text":1078,"url":20,"identifiers":1079},"P. K. Selbo, M. G. Rosenblum, L. H. Cheung, W. Zhang, K. Berg, PLoS One, 2009, 4, e6691.",{"doi":1080},"10.1371\u002Fjournal.pone.0006691",{"id":20,"text":1082,"url":20,"identifiers":1083},"K. Berg, S. Nordstrand, P. K. Selbo, D. T. T. Tran, E. Angell-Petersen, A. Høgset, Photochem. Photobiol. Sci., 2011, 10, 1637–1651.",{"doi":1084},"10.1039\u002Fc1pp05128h",{"id":20,"text":1086,"url":20,"identifiers":1087},"R. W. Redmond, J. N. Gamlin, Photochem. Photobiol., 1999, 70, 391–475.",{"doi":1088},"10.1562\u002F0031-8655(1999)070\u003C0391:ACOSOY>2.3.CO;2",{"id":20,"text":1090,"url":20,"identifiers":1091},"C. Tanielian, C. Wolff, J. Phys. Chem., 1995, 99, 9825–9830.",{"doi":1092},"10.1021\u002Fj100024a025",{"id":20,"text":1094,"url":20,"identifiers":1095},"K. Berg, A. Weyergang, L. Prasmickaite, A. Bonsted, A. Høgset, M.-T. R. Strand, E. Wagner, P. K. Selbo, Methods Mol. Biol., 2010, 635, 133–146.",{"doi":1096},"10.1007\u002F978-1-60761-697-9_10",{"id":20,"text":1098,"url":20,"identifiers":1099},"L. Kunz, J. P. Connelly, J. H. Woodhams, A. J. MacRobert, Photochem. Photobiol. Sci., 2007, 6, 940–948.",{"doi":1100},"10.1039\u002Fb708456k",{"id":20,"text":1102,"url":20,"identifiers":1103},"J. T.-W. Wang, PhD Thesis, University College London, 2010.",{},{"id":20,"text":1105,"url":20,"identifiers":1106},"J. T. W. Wang, F. Giuntini, I. M. Eggleston, S. G. Bown, A. J. MacRobert, J. Controlled Release, 2012, 157, 305–313.",{"doi":1107},"10.1016\u002Fj.jconrel.2011.08.025",{"id":20,"text":1109,"url":20,"identifiers":1110},"H. Mojzisova, S. Bonneau, P. Maillard, K. Berg, D. Brault, Photochem. Photobiol. Sci., 2009, 8, 778–787.",{"doi":1111},"10.1039\u002Fb822269j",{"id":20,"text":1113,"url":20,"identifiers":1114},"R. Bonnett, P. Charlesworth, B. D. Djelal, S. Foley, D. J. McGarvey, T. G. Truscott, J. Chem. Soc., Perkin Trans. 2, 1999, 325–328.",{},{"id":20,"text":1116,"url":20,"identifiers":1117},"M. Wacker, K. Chen, A. Preuss, K. Possemeyer, B. Roeder, K. Langer, Int. J. Pharm., 2010, 393, 254–262.",{"doi":1118},"10.1016\u002Fj.ijpharm.2010.04.022",{"id":20,"text":1120,"url":20,"identifiers":1121},"S. M. Bishop, A. Beeby, H. Meunier, A. W. Parker, M. S. C. Foley, D. Phillips, J. Chem. Soc., Faraday Trans., 1996, 92, 2689–2695.",{"doi":1122},"10.1039\u002Fft9969202689",{"id":20,"text":1124,"url":20,"identifiers":1125},"C. Tanielian, C. Wolff, M. Esch, J. Phys. Chem., 1996, 100, 6555–6560.",{"doi":1126},"10.1021\u002Fjp952107s",{"id":20,"text":1128,"url":20,"identifiers":1129},"M. Lilletvedt, S. Kristensen, H. H. Tonnesen, A. Hogset, L. Nardo, J. Photochem. Photobiol., A, 2010, 214, 40–47.",{"doi":1130},"10.1016\u002Fj.jphotochem.2010.06.004",{"id":20,"text":1132,"url":20,"identifiers":1133},"M. Lilletvedt, H. H. Tonnesen, A. Hogset, L. Nardo, S. Kristensen, Pharmazie, 2010, 65, 588–595.",{},{"id":20,"text":1135,"url":20,"identifiers":1136},"K. G. de Bruin, C. Fella, M. Ogris, E. Wagner, N. Ruthardt, C. Bräuchle, J. Controlled Release, 2008, 130, 175–182.",{"doi":1137},"10.1016\u002Fj.jconrel.2008.06.001",{"id":20,"text":1139,"url":20,"identifiers":1140},"D. Phillips, S. Dhami, R. Ostler, Z. Petrasek, The dimerisation of phthalocyanines, Prog. React. Kinet. Mech., 2003, 28, 299–420.",{"doi":1141},"10.3184\u002F007967403322807390",{"id":20,"text":1143,"url":20,"identifiers":1144},"M. Pawlicki, H. A. Collins, R. G. Denning, H. L. Anderson, Angew. Chem., Int. Ed., 2009, 48, 3244–3266.",{"doi":1145},"10.1002\u002Fanie.200805257",{"id":20,"text":1147,"url":20,"identifiers":1148},"H. P. Lassalle, D. Dumas, S. Graefe, M. A. D’Hallewin, F. Guillemin, L. Bezdetnaya, J. Controlled Release, 2009, 134, 118–124.",{"doi":1149},"10.1016\u002Fj.jconrel.2008.11.016",{"id":20,"text":1151,"url":20,"identifiers":1152},"J. P. Connelly, S. W. Botchway, L. Kunz, D. Pattison, A. W. Parker, A. J. Macrobert, J. Photochem. Photobiol., A, 2001, 142, 169–175.",{"doi":1153},"10.1016\u002FS1010-6030(01)00511-1",{"id":20,"text":1155,"url":20,"identifiers":1156},"M. Kress, T. Meier, R. Steiner, F. Dolp, R. Erdmann, U. Ortmann, A. Ruck, J. Biomed. Opt., 2003, 8, 26–32.",{"doi":1157},"10.1117\u002F1.1528595",{"id":20,"text":1159,"url":20,"identifiers":1160},"R. W. Boyle, D. Dolphin, Photochem. Photobiol., 1996, 64, 469–485.",{"doi":1161},"10.1111\u002Fj.1751-1097.1996.tb03093.x",{"id":20,"text":1163,"url":20,"identifiers":1164},"A. D. Scully, R. B. Ostler, D. Phillips, P. O’Neill, K. M. S. Townsend, A. W. Parker, A. J. MacRobert, Bioimaging, 1997, 5, 9–18.",{"doi":1165},"10.1002\u002F1361-6374(199703)5:1\u003C9::AID-BIO2>3.3.CO;2-1",{"id":1167,"createTime":1168,"updateTime":1169,"relativeEntities":1170,"slug":1171,"properties":1172,"entityType":192,"verifyStatus":193,"verifyTime":1185,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":1186,"fullTextUrl":20,"authors":1187,"publicationType":245,"publisherRelationship":1263,"citationCount":21,"citationInfo":1305,"publishDate":1308,"publishYear":1306,"citationAnalyzeStatus":19,"lastCitationAnalyze":1169,"indexDatabases":1309,"openAccess":20,"references":20,"isForceReanalyzing":412},"3f98d791-962e-4f10-80c6-1c761c4c328a","2024-04-08T23:36:34.191+00:00","2026-07-22T15:09:01.774+00:00",[],"Early-detection-of-stripe-rust-infection-in-wheat-using-light-induced-fluorescence-spectroscopy",{"abstract":1173,"title":1175,"gsPaper":1177,"keywords":1179,"references":1181,"doi":1183},{"EN":1174},"In the current study, the application of fluorescence spectroscopy along with the advanced statistical technique and confocal microscopy was investigated for the early detection of stripe rust infection in wheat grown under field conditions. The indigenously developed Fluorosensor fitted with LED, emitting monochromatic light was used that covered comparatively larger leaf area for recording fluorescence data thus presenting more reliable current status of the leaf. The examined leaf samples covered the entire range of stripe rust disease infection from no visible symptoms to the complete disease prevalence. The molecular changes were also assessed in the leaves as the disease progresses. The emission spectra mainly produce two fluorescence emission classes, namely the blue-green fluorescence (400–600 nm range) and chlorophyll fluorescence (650–800 nm range). The chlorophyll fluorescence region showed lower chlorophyll bands both at 685 and 735 nm in the asymptomatic (early diseased) and symptomatic (diseased) leaf samples than the healthy ones as a result of partial deactivation of PSII reaction centers. The 735 nm chlorophyll fluorescence band was either slight or completely absent in the leaf samples with lower to higher disease incidence and thus differentiate between the healthy and the infected leaf samples. The Hydroxycinnamic acids (caffeic and sinapic acids) showed decreasing trend, whereas the ferulic acid increased with the rise in disease infection. Peak broadening\u002Fshifting has been observed in case of ferulic acid and carotenes\u002Fcarotenoids, with the increase in the disease intensity. While using the LEDs (365 nm), the peak broadening and the decline in the chlorophyll fluorescence bands could be used for the early prediction of stripe rust disease in wheat crop. The PLSR statistical techniques discriminated well between the healthy and the diseased samples, thus showed promise in early disease detection. Confocal microscopy confirmed the early prevalence of stripe rust disease infection in a susceptible variety at a stage when the disease is not detectable visually. It is inferred that fluorescence emission spectroscopy along with the chemometrics aided in the effective and timely diagnosis of plant diseases and the detected signatures provide the basis for remote sensing. \n                  \n                    \n                      \n                    \n                  \n                ",{"EN":1176},"Early detection of stripe rust infection in wheat using light-induced fluorescence spectroscopy",{"VOID":1178},"[\"4255170482932598429\"]",{"EN":1180},"",{"VOID":1182},"UN, World population prospects: The 2012 revision. Retrieved from https:\u002F\u002Fwww.un.org\u002Fen\u002Fdevelopment\u002Fdesa\u002Fpublications\u002Fworld-population-prospects-the-2012-revision.html. Accessed 3 Sep 2021\nFróna, D., Szenderák, J., & Harangi-Rákos, M. (2019). The challenge of feeding the world. Sustainability, 11, 5816.\nShikur, Z. H. (2020). Agricultural policies, agricultural production and rural households’ welfare in Ethiopia. Journal of Economics Structure, 9, 1–21.\nNikolić, B. R., Pavlović, D. M., Đurović, S., Waisi, H., Marisavljević, D., & Anđelković, A. (2014). Chlorophyll as a measure of plant health: Agroecological aspects. Pestic Phytomedicine\u002FPestic I Fitomedicina, 29, 21–34. https:\u002F\u002Fdoi.org\u002F10.2298\u002Fpif.v29i1.5121\nS. Patterson, Understanding the role of magnesium in plants—How do plants use magnesium. Retrieved from https:\u002F\u002Fwww.gardeningknowhow.com\u002Fgarden-how-to\u002Fsoil-fertilizers\u002Ffixing-magnesium-deficiency.htm. Accessed 25 Nov 2021\nPina-Oviedo, S., Ortiz-Hidalgo, C., & Ayala, A. G. (2017). Human Colors—The rainbow garden of pathology: What gives normal and pathologic tissues their color? Archives of Pathology and Laboratory Medicine, 141, 445–462.\nAbbaspour, N., Hurrell, R., & Kelishadi, R. (2014). Review on iron and its importance for human health. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 19, 164.\nGröber, U., Schmidt, J., & Kisters, K. (2015). Magnesium in prevention and therapy. Nutrients, 7, 8199.\nYahia, E. M., Carrillo-López, A., Barrera, G. M., Suzán-Azpiri, H., & Bolaños, M. Q. (2019). Postharvest Physiology and Biochemistry of Fruits and Vegetables (pp. 47–72). Woodhead Publishing. https:\u002F\u002Fdoi.org\u002F10.1016\u002FB978-0-12-813278-4.00003-8\nNatGeoSoc, Photosynthesis|National Geographic Society. Retrieved from https:\u002F\u002Fwww.nationalgeographic.org\u002Fencyclopedia\u002Fphotosynthesis\u002F. Accessed 15 Dec 2021.\nKhorobrykh, S., Havurinne, V., Mattila, H., & Tyystjärvi, E. (2020). Oxygen and ROS in photosynthesis. Plants, 9, 91. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fplants9010091\nSoll, J., & Schleiff, E. (2004). Protein import into chloroplasts. Nature Reviews Molecular Cell Biology, 5, 198–208.\nNature Education, contents of essentials of cell biology|learn science at scitable. Retrieved from https:\u002F\u002Fwww.nature.com\u002Fscitable\u002Febooks\u002Fessentials-of-cell-biology-14749010\u002F122996720\u002F. Accessed 16 Dec 2021\nBayat, L., Arab, M., Aliniaeifard, S., Seif, M., Lastochkina, O., & Li, T. (2018). Effects of growth under different light spectra on the subsequent high light tolerance in rose plants. AoB Plants, 10, 1–9.\nGiraldo, P., Benavente, E., Manzano-Agugliaro, F., & Gimenez, E. (2019). Worldwide research trends on wheat and barley: A bibliometric comparative analysis. Agronomy, 9, 352. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fagronomy9070352\nFigueroa, M., Hammond-Kosack, K. E., & Solomon, P. S. (2018). A review of wheat diseases—A field perspective. Molecular Plant Pathology, 19, 1523–1536.\nChen, Y. E., Cui, J. M., Su, Y. Q., Yuan, S., Yuan, M., & Zhang, H. Y. (2015). Influence of stripe rust infection on the photosynthetic characteristics and antioxidant system of susceptible and resistant wheat cultivars at the adult plant stage. Frontiers in Plant Science, 6, 779.\nAli, S., Leconte, M., Rahman, H., Saqib, M. S., Gladieux, P., Enjalbert, J., & de Vallavieille-Pope, C. (2014). A high virulence and pathotype diversity of Puccinia striiformis f.sp. tritici at its centre of diversity, the Himalayan region of Pakistan. European Journal of Plant Pathology, 140, 275–290.\nAli, S., Gladieux, P., Leconte, M., Gautier, A., Justesen, A. F., Hovmøller, M. S., Enjalbert, J., & de Vallavieille-Pope, C. (2014). Origin, migration routes and worldwide population genetic structure of the wheat yellow rust pathogen Puccinia striiformis f.sp. tritici. PLoS Pathogology, 10, 1003903.\nChen, X., Moore, M., Milus, E. A., Long, D. L., Line, R. F., Marshall, D., & Jackson, L. (2002). Wheat stripe rust epidemics and races of Puccinia striiformis f sp tritici in the United States in 2000. Plant Disease, 86, 39–46.\nAli, S., Rodriguez-Algaba, J., Thach, T., Sørensen, C. K., Hansen, J. G., Lassen, P., Nazari, K., Hodson, D. P., Justesen, A. F., & Hovmøller, M. S. (2017). Yellow rust epidemics worldwide were caused by pathogen races from divergent genetic lineages. Frontiers in Plant Science, 8, 1–13. https:\u002F\u002Fdoi.org\u002F10.3389\u002Ffpls.2017.01057\nAtta, B. M., Saleem, M., Ali, H., Bilal, M., & Fayyaz, M. (2020). Application of fluorescence spectroscopy in wheat crop: Early disease detection and associated molecular changes. Journal of Fluorescence, 30, 801–810.\nLine, R. F. (2002). Stripe rust of wheat and barley in North America: A retrospective historical review. Annual review of Phytopathology, 40, 75–118.\nMehmood, S., Sajid, M., Zhao, J., Huang, L., & Kang, Z. (2020). Alternate hosts of Puccinia striiformis f. sp. tritici and their role. Pathogens, 9, 434.\nSaleem, M., Atta, B. M., Ali, Z., & Bilal, M. (2020). Laser-induced fluorescence spectroscopy for early disease detection in grapefruit plants. Photochemical and Photobiological Sciences, 19, 713–721.\nBuschmann, C. (2007). Variability and application of the chlorophyll fluorescence emission ratio red\u002Ffar-red of leaves. Photosynthesis Research, 92, 261–271.\nGouveia-neto, A. S., Silva-jr, E. A., Cunha, P. C., Oliveira-filho, R., Silva, L. M. H., Costa, E. B., Câmara, T. J. R., & Willadino, L. G. (2011). Biofuel production-recent developments and prospects (pp. 1–22). InTech.\nBürling, K., Hunsche, M., & Noga, G. (2011). Use of blue-green and chlorophyll fluorescence measurements for differentiation between nitrogen deficiency and pathogen infection in winter wheat. Journal of Plant Physiology, 168, 1641–1648.\nLenk, S., Gádoros, P., Kocsányi, L., & Barócsi, A. (2016). Teaching laser-induced fluorescence of plant leaves. European Journal of Physics, 37, 064003.\nRanulfi, A. C., Cardinali, M. C. B., Kubota, T. M. K., Freitas-Astúa, J., Ferreira, E. J., Bellete, B. S., da Silva, M. F. G. F., Villas Boas, P. R., Magalhães, A. B., & Milori, D. M. B. P. (2016). Laser-induced fluorescence spectroscopy applied to early diagnosis of citrus Huanglongbing. Biosystem Engineering, 144, 133–144.\nHe, R., Li, H., Qiao, X., & Jiang, J. (2018). Using wavelet analysis of hyperspectral remote-sensing data to estimate canopy chlorophyll content of winter wheat under stripe rust stress. International Journal of Remote Sensing, 39, 4059–4076.\nRobert, C., Bancal, M. O., Ney, B., & Lannou, C. (2005). Wheat leaf photosynthesis loss due to leaf rust, with respect to lesion development and leaf nitrogen status. New Phytologist, 165, 227–241.\nKang, Z., Tang, C., Zhao, J., Cheng, Y., Liu, J., Guo, J., Wang, X., & Chen, X. (2017). Stripe rust (pp. 155–282). Dordrecht: Springer. https:\u002F\u002Fdoi.org\u002F10.1007\u002F978-94-024-1111-9_3\nKhanfri, S., Boulif, M., & Lahlali, R. (2018). Yellow rust (Puccinia striiformis): A serious threat to wheat production worldwide. Notation Science Biology, 10, 410–423. https:\u002F\u002Fdoi.org\u002F10.15835\u002Fnsb10310287\nCarmona, M., Sautua, F., Pérez-Hérnandez, O., & Reis, E. M. (2020). Role of fungicide applications on the integrated management of wheat stripe rust. Frontiers in Plant Science, 11, 733.\nWSU, Stripe Rust|Wheat and Small Grains|Washington State University. Retrieved form https:\u002F\u002Fsmallgrains.wsu.edu\u002Fdisease-resources\u002Ffoliar-fungal-diseases\u002Fstripe-rust\u002F. Accessed 7 Feb 2022\nAtta, B. M., Saleem, M., Ali, H., Arshad, H. M. I., & Ahmed, M. (2018). Chlorophyll as a biomarker for early disease diagnosis. Laser Physics, 28, 065607.\nSankaran, S., Mishra, A., Ehsani, R., & Davis, C. (2010). A review of advanced techniques for detecting plant diseases. Computers and Electronics in Agriculture, 72, 1–13.\nAli, M. M., Bachik, N. A., Atirah Muhadi, N., Tuan Yusof, T. N., & Gomes, C. (2019). Non-destructive techniques of detecting plant diseases: A review. Physiology Molecular Plant PatholOGY, 108, 101426.\nKumar, P., Akhtar, J., Kandan, A., Kumar, S., Batra, R., & Dubey, S. C. (2016). Current trends in plant disease diagnostics and management practices, fungal biology (pp. 265–298). Springer. https:\u002F\u002Fdoi.org\u002F10.1007\u002F978-3-319-27312-9_12\nCerovic, Z. G., Samson, G., Morales, F., Tremblay, N., & Moya, I. (1999). Ultraviolet-induced fluorescence for plant monitoring: Present state and prospects. Agronomie, 19, 543–578. https:\u002F\u002Fdoi.org\u002F10.1051\u002Fagro:19990701\nBelasque, J., Jr., Gasparoto, M. C. G., & Marcassa, L. G. (1922). Detection of mechanical and disease stresses in citrus plants by fluorescence spectroscopy. Applied Optics, 2008, 47.\nAtta, B. M., Saleem, M., Ali, H., Ali, Z., & Zakria, M. (2019). Synchronous fluorescence spectroscopy for early diagnosis of citrus canker in citrus species. Laser Physics, 29, 085604.\nBharti, A. S., Sharma, S., Singh, A. K., Tiwari, M. K., & Uttam, K. N. (2021). Assessment of the elemental profile of leafy vegetables by synchrotron-radiation-induced energy dispersive X-ray fluorescence spectroscopy. Journal of Applied Spectroscopy, 88, 653–661.\nBharti, A. S., Sharma, S., Shukla, N., Tiwari, M. K., & Uttam, K. N. (2017). Elemental investigation of the leaf and seed of coriander plant by synchrotron radiation X-ray fluorescence spectroscopy. National Academy of Science Letters, 40, 373–377. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs40009-017-0600-3\nSharma, S., Sharma, S., Bharti, A. S., Tiwari, M. K., & Uttam, K. N. (2022). Non-destructive assessment of the nutrient profile of underutilized seeds using spectroscopic probes. Analytical Letters, 1, 1–17.\nSharma, S., Baran, C., Tripathi, A., Awasthi, A., Jaiswal, A., Uttam, R., Bharti, A. S., Singh, R., & Uttam, K. N. (2021). Phytochemical screening of the different cultivars of Ixora flowers by non-destructive, label-free, and rapid spectroscopic techniques. Analytical Letters, 54, 2276–2292.\nSharma, S., Uttam, R., Singh, P., & Uttam, K. N. (2018). Detection of vibrational spectroscopic biomarkers of the effect of gold nanoparticles on wheat seedlings using attenuated total reflectance fourier transform infrared spectroscopy. Analytical Letters, 51, 2271–2294.\nSharma, S., Uttam, R., & Uttam, K. N. (2020). Interaction of chlorophyll with titanium dioxide and iron oxide nanoparticles: A temperature dependent fluorescence quenching study. Analytical Letters, 53, 1851–1870.\nSharma, S., Uttam, R., Sarika Bharti, A., & Uttam, K. N. (2019). Interaction of zinc oxide and copper oxide nanoparticles with chlorophyll: A fluorescence quenching study. Analytical Letters, 52, 1539–1557.\nSharma, S., & Uttam, K. N. (2019). Non-invasive monitoring of biochemical response of wheat seedlings toward titanium dioxide nanoparticles treatment using attenuated total reflectance fourier transform infrared and laser induced fluorescence spectroscopy. Analytical Letters, 52, 1629–1652.\nSharma, S., & Uttam, K. N. (2017). Rapid analyses of stress of copper oxide nanoparticles on wheat plants at an early stage by laser induced fluorescence and attenuated total reflectance Fourier transform infrared spectroscopy. Vibrational Spectroscopy, 92, 135–150.\nBharti, A. S., Sharma, S., Shukla, N., & Uttam, K. N. (2018). Steady state and time resolved laser-induced fluorescence of garlic plants treated with titanium dioxide nanoparticles. Spectroscopy Letters, 51, 45–54.\nTripathi, A., Baran, C., Jaiswal, A., Awasthi, A., Uttam, R., Sharma, S., Bharti, A. S., Singh, R., & Uttam, K. N. (2020). Investigating the carotenogenesis process in papaya fruits during maturity and ripening by non-destructive spectroscopic probes. Analytical Letters, 53, 2903–2920.\nSharma, S., Srivastava, S., Singh, R., & Uttam, K. N. (2017). Label-free and rapid spectroscopic evaluation of ripening of Syzygium cumini fruit. Spectroscopy Letters, 50, 115–123.\nSharma, S., Sarika Bharti, A., Singh, R., & Uttam, K. N. (2019). Non-destructive phenotyping of chili pepper ripening using spectroscopic probes: A potential approach for shelf-life measurement. Analytical Letters, 52, 1590–1613.\nKumar, G., Srivastava, P., Pandey, J. K., & Gopal, R. (2010). Effect of laser-irradiation on photosynthetic efficiency of safflower leaves. Journal of Phytology, 2, 13–16. http:\u002F\u002Fwww.journal-phytology.com.\nRahman, M. A., Pandey, J. K., Sundaram, S., & Gopal, R. (2015). Response of growth, photosynthetic pigments, laser-induced pigment fluorescence, antioxidant enzymes and lipid peroxidation to ultraviolet-B radiation in two cyanobacteria. Indian Journal of Plant Physiology, 20, 240–248. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs40502-015-0169-0\nSankaran, S., & Ehsani, R. (2012). Detection of Huanglongbing disease in citrus using fluorescence spectroscopy. Transactions of the ASABE, 55, 313–320.\nTischler, Y. K., Thiessen, E., & Hartung, E. (2018). Early optical detection of infection with brown rust in winter wheat by chlorophyll fluorescence excitation spectra. Computers and Electronics in Agriculture, 146, 77–85.\nRömer, C., Bürling, K., Hunsche, M., Rumpf, T., Noga, G., & Plümer, L. (2011). Robust fitting of fluorescence spectra for pre-symptomatic wheat leaf rust detection with Support Vector Machines. Computers and Electronics in Agriculture, 79, 180–188.\nBurling, K., Hunsche, M., Noga, G., Pfeifer, L., & Damerow, L. (2011). UV-induced fluorescence spectra and lifetime determination for detection of leaf rust (Puccinia triticina) in susceptible and resistant wheat (Triticum aestivum) cultivars. Functional Plant Biology, 38, 337–345.\nBürling, K., Hunsche, M., & Noga, G. (2012). Presymptomatic detection of powdery mildew infection in winter wheat cultivars by laser-induced fluorescence. Applied Spectroscopy, 66, 1411–1419.\nBauriegel, E., & Herppich, W. (2014). Hyperspectral and chlorophyll fluorescence imaging for early detection of plant diseases, with special reference to fusarium spec. infections on wheat. Agriculture, 4, 32–57. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fagriculture4010032\nSharma, S., & Uttam, K. N. (2018). Early stage detection of stress due to copper on maize (Zea mays L.) by laser-induced fluorescence and infrared spectroscopy. Journal of Applied Spectroscopy, 85, 771–780.\nMaurya, R., Prasad, S. M., & Gopal, R. (2008). LIF technique offers the potential for the detection of cadmium-induced alteration in photosynthetic activities of Zea mays L. Journal of Photochemistry Photobiology C Photochemistry Review, 9, 29–35. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jphotochemrev.2008.03.001\nSharma, S., Sarika Bharti, A., Tiwari, M. K., & Uttam, K. N. (2018). Effect of manganese stress on the mineral content of the leaves of wheat seedlings by use of X-ray fluorescence excited by synchrotron radiation. Spectroscopy Letters, 51, 302–310.\nSharma, S., & Uttam, K. N. (2018). Nondestructive and rapid probing of biochemical response of arsenic stress on the leaves of wheat seedlings using attenuated total reflectance fourier transform infrared spectroscopy. Analytical Letters, 52, 268–287.\nSharma, S., Singh, A. K., Tiwari, M. K., & Uttam, K. N. (2020). Prompt screening of the alterations in biochemical and mineral profile of wheat plants treated with chromium using attenuated total reflectance fourier transform infrared spectroscopy and X-ray fluorescence excited by synchrotron radiation. Analytical Letters, 53, 482–508.\nMishra, K. B., & Gopal, R. (2008). Detection of nickel-induced stress using laser-induced fluorescence signatures from leaves of wheat seedlings. International Journal of Remote Sensing, 29, 157–173. https:\u002F\u002Fdoi.org\u002F10.1080\u002F01431160701280975\nPandey, J. K., & Gopal, R. (2011). Laser-induced chlorophyll fluorescence: A technique for detection of dimethoate effect on chlorophyll content and photosynthetic activity of wheat plant. Journal of Fluorescence, 21, 785–791. https:\u002F\u002Fdoi.org\u002F10.1007\u002Fs10895-010-0771-5\nPandey, J. K., & Gopal, R. (2011). Laser-induced chlorophyll fluorescence and reflectance spectroscopy of cadmium treated Triticum aestivum L. plants. Spectroscopy, 26, 129–139. https:\u002F\u002Fdoi.org\u002F10.3233\u002Fspe-2011-0530\nMishra, K. B., & Gopal, R. (2005). Study of laser-indused fluorescence signatures from leaves of wheat seedlings growing under cadmium stress. General and Applied Plant Physiology, 31, 181–196.\nGopal, R., Mishra, K. B., Zeeshan, M., Prasad, S. M., & Joshi, M. M. (2002). Laser-induced chlorophyll fluorescence spectra of mung plants growing under nickel stress. Current Science, 83, 880–884. https:\u002F\u002Fwww.jstor.org\u002Fstable\u002F24107093.\nPandey, J. K., Srivastava, P., Yadav, R. S., & Gopal, R. (2012). Chlorophyll fluorescence spectra as an indicator of X-ray + EMS-induced phytotoxicity in safflower. Spectroscopy (New York), 27, 207–214. https:\u002F\u002Fdoi.org\u002F10.1155\u002F2012\u002F951064\nMaurya, R., & Gopal, R. (2008). Laser-induced fluorescence ratios of Cajanus cajan L. under the stress of cadmium and its correlation with pigment content and pigment ratios. Applied Spectroscopy, 62, 433–438. https:\u002F\u002Fdoi.org\u002F10.1366\u002F000370208784046687\nE. H. & Woldeab, N. B. G. Stem rust collection, processing, and inoculation | BGRI Training. Retrieved from https:\u002F\u002Ftraining.globalrust.org\u002Fmanuals\u002Frace-analysis\u002Fchapter-3. Accessed 20 Aug 2021.\nClaxton, N. S., Fellers, T. J., & Davidson, M. W. (2006). Encyclopedia of medical devices and instrumentation (2nd ed., pp. 449–477). Wiley. https:\u002F\u002Fdoi.org\u002F10.1002\u002F0471732877.emd291\nMaxwell, K., & Johnson, G. N. (2000). Chlorophyll fluorescence—A practical guide. Journal of Experimantal Botany, 51, 659–668.\nMüller, P., Li, X. P., & Niyogi, K. K. (2001). Non-photochemical quenching. A response to excess light energy. Plant Physiology, 125, 1558–1566.\nFalco, W. F., Botero, E. R., Falcão, E. A., Santiago, E. F., Bagnato, V. S., & Caires, A. R. L. (2011). In vivo observation of chlorophyll fluorescence quenching induced by gold nanoparticles. Journal of Photochemistry and Photobiology, A Chemistry, 225, 65–71. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.jphotochem.2011.09.027\nUllah, R., Khan, S., Bilal, M., Nurjis, F., & Saleem, M. (2016). Non-invasive assessment of mango ripening using fluorescence spectroscopy. Optik (Stuttg), 127, 5186–5189.\nStrassburg, C. P., & Kalthoff, S. (2015). Coffee in health and disease prevention (pp. 535–543). Academic Press.\nZhang, Y., Cai, P., Cheng, G., & Zhang, Y. (2022). A brief review of phenolic compounds identified from plants: Their extraction, analysis, and biological activity. Natural Products Communications, 17, 1–14. https:\u002F\u002Fdoi.org\u002F10.1177\u002F1934578X211069721\nLagorio, M. G., Cordon, G. B., & Iriel, A. (2015). Reviewing the relevance of fluorescence in biological systems. Photochemical and Photobiological Sciences, 14, 1538–1559. https:\u002F\u002Fdoi.org\u002F10.1039\u002Fc5pp00122f\nLang, M., Stober, F., & Lichtenthaler, H. K. (1991). Fluorescence emission spectra of plant leaves and plant constituents. Radiation and Environmental Biophysics, 30, 333–347.\nEl-Basyouni, S., & Towers, G. H. N. (1964). The phenolic acids in wheat: I. Changes during growth and development. Canadian Journal of Biochemistry, 42, 203–210.\nLichtenthaler, H. K., & Schweiger, J. (1998). Cell wall bound ferulic acid, the major substance of the blue-green fluorescence emission of plants. Journal of Plant Physiology, 152, 272–282.\nBarron, C., Surget, A., & Rouau, X. (2007). Relative amounts of tissues in mature wheat (Triticum aestivum L.) grain and their carbohydrate and phenolic acid composition. Journal of Cereal Science, 45, 88–96.\nLi, L., Shewry, P. R., & Ward, J. L. (2008). Phenolic acids in wheat varieties in the healthgrain diversity screen. Journal of Agriculture and Food Chemistry, 56, 9732–9739.\nSoutherton, S. G., & Deverall, B. J. (1990). Changes in phenolic acid levels in wheat leaves expressing resistance to Puccinia recondita f. sp. tritici. Physiology Molecular Plant Pathology, 37, 437–450.\nMeyer, S., Cartelat, A., Moya, I., & Cerovic, Z. G. (2003). UV-induced blue-green and far-red fluorescence along wheat leaves: A potential signature of leaf ageing. Journal of Experimental Botany, 54, 757–769.\nMoore, J., Hao, Z., Zhou, K., Luther, M., Costa, J., & Yu, L. (2005). Carotenoid, tocopherol, phenolic acid, and antioxidant properties of Maryland-grown soft wheat. Journal of Agriculture and Food Chemistry, 53, 6649–6657.\nŽilić, S., Hadži-Tašković Šukalović, V., Dodig, D., Maksimović, V., Maksimović, M., & Basić, Z. (2011). Antioxidant activity of small grain cereals caused by phenolics and lipid soluble antioxidants. Journal of Cereal Science, 54, 417–424.\nTajner-Czopek, A., Gertchen, M., Rytel, E., Kita, A., Kucharska, A. Z., & Sokół-Łętowska, A. (2020). Study of antioxidant activity of some medicinal plants having high content of caffeic acid derivatives. Antioxidants, 9, 1–21. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fantiox9050412\nAgunloye, O. M., Oboh, G., Ademiluyi, A. O., Ademosun, A. O., Akindahunsi, A. A., Oyagbemi, A. A., Omobowale, T. O., Ajibade, T. O., & Adedapo, A. A. (2019). Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid: Mechanistic role of angiotensin converting enzyme, cholinesterase and arginase activities in cyclosporine induced hypertensive rats. Biomedicine and Pharmacotherapy, 109, 450–458.\nNićiforović, N., & Abramovič, H. (2014). Sinapic acid and its derivatives: Natural sources and bioactivity. Comprehensive Review Food Science Food Safety, 13, 34–51.\nBurkhow, S. J., Stephens, N. M., Mei, Y., Dueñas, M. E., Freppon, D. J., Ding, G., Smith, S. C., Lee, Y. J., Nikolau, B. J., Whitham, S. A., & Smith, E. A. (2018). Characterizing virus-induced gene silencing at the cellular level with in situ multimodal imaging. Plant Methods, 14, 1–12.\nGitelson, A. A., Keydan, G. P., & Merzlyak, M. N. (2006). Three-band model for noninvasive estimation of chlorophyll, carotenoids, and anthocyanin contents in higher plant leaves. Geophysical Research Letters, 33, L11402.\nStober, F., & Lichtenthaler, H. K. (1992). Changes of the laser-induced blue, green and red fluorescence signatures during greening of etiolated leaves of wheat. Journal of Plant Physiology, 140, 673–680.\nDevadas, R., Lamb, D. W., Backhouse, D., & Simpfendorfer, S. (2015). Sequential application of hyperspectral indices for delineation of stripe rust infection and nitrogen deficiency in wheat. Precision Agriculture, 16, 477–491.\nOgawa, T., Inoue, Y., Kitajima, M., & Shibata, K. (1973). Action spectra for biosynthesis of chlorophylls a and b and β-carotene. Photochemistry and Photobiology, 18, 229–235.\nTambussi, E. A., Casadesus, J., Munné-Bosch, S., & Araus, J. L. (2002). Photoprotection in water-stressed plants of durum wheat (Triticum turgidum var. durum): Changes in chlorophyll fluorescence, spectral signature and photosynthetic pigments. Functional Plant Biology, 29, 35–44.\nBauriegel, E., Giebel, A., Geyer, M., Schmidt, U., & Herppich, W. B. (2011). Early detection of Fusarium infection in wheat using hyper-spectral imaging. Computers and Electronics in Agriculture, 75, 304–312.\nBuschmann, C., Langsdorf, G., & Lichtenthaler, H. K. (2000). Imaging of the blue, green, and red fluorescence emission of plants: An overview. Photosynthetica, 38, 483–491.\nHardham, A. R. (2012). Plant fungal pathogens: Methods and protocols, methods in molecular biology (Vol. 835, pp. 295–309). Springer. https:\u002F\u002Fdoi.org\u002F10.1007\u002F978-1-61779-501-5_18\nFirdous, S. (2018). Optical fluorescence diagnostic of wheat leaf rust with laser scanning confocal microscopy. Advance Crop Science Technology, 06, 2–5. https:\u002F\u002Fdoi.org\u002F10.4172\u002F2329-8863.1000355\nHa, X., Koopmann, B., & Von Tiedemann, A. (2016). Wheat blast and fusarium head blight display contrasting interaction patterns on ears of wheat genotypes differing in resistance. Phytopathology, 106, 270–281.\nChen, D., Muhae-Ud-din, G., Liu, T., Chen, W., Liu, C., & Gao, L. (2021). Wheat varietal response to Tilletia controversa j. G. kühn using qrt-pcr and laser confocal microscopy. Genes (Basel), 12, 425.\nHutzler, P., Fischbach, R., Heller, W., Jungblut, T. P., Reuber, S., Schmitz, R., Veit, M., Weissenböck, G., & Schnitzler, J. P. (1998). Tissue localization of phenolic compounds in plants by confocal laser scanning microscopy. Journal of Experimental Botany, 49, 953–965.\nSaadi, A., Lempereur, I., Sharonov, S., Autran, J. C., & Manfait, M. (1998). Spatial distribution of phenolic materials in durum wheat grain as probed by confocal fluorescence spectral imaging. Journal of Cereal Science, 28, 107–114.\nPiot, O., Autran, J. C., & Manfait, M. (2000). Spatial distribution of protein and phenolic constituents in wheat grain as probed by confocal raman microspectroscopy. Journal of Cereal Science, 32, 57–71.\nMoldenhauer, J., Pretorius, Z. A., Moerschbacher, B. M., Prins, R., & Van Der Westhuizen, A. J. (2008). Histopathology and PR-protein markers provide insight into adult plant resistance to stripe rust of wheat. Molecular Plant Pathology, 9, 137–145.\nMoldenhauer, J., Moerschbacher, B. M., & Van Der Westhuizen, A. J. (2006). Histological investigation of stripe rust (Puccinia striiformis f.sp. tritici) development in resistant and susceptible wheat cultivars. Plant Pathology, 55, 469–474.\nCartwright, D. W., & Russell, G. E. (1981). Development of Puccinia striiformis in a susceptible winter wheat variety. Transactions of the British Mycological Society, 76, 197–204. https:\u002F\u002Fdoi.org\u002F10.1016\u002FS0007-1536(81)80139-8\nJha, S. N., & Ruchi, G. (2010). Non-destructive prediction of quality of intact apple using near infrared spectroscopy. Journal of Food Science and Technology, 47, 207–213.\nAshourloo, D., Aghighi, H., Matkan, A. A., Mobasheri, M. R., & Rad, A. M. (2016). An investigation into machine learning regression techniques for the leaf rust disease detection using hyperspectral measurement. IEEE Journal of Selected Topics Applied Earth Observation Remote Sensors, 9, 4344–4351.\nKrishna, G., Sahoo, R. N., Pargal, S., Gupta, V. K., Sinha, P., Bhagat, S., Saharan, M. S., Singh, R., & Chattopadhyay, C. (2014). Assessing wheat yellow rust disease through hyperspectral remote sensing. International Archives Photogrammetry Remote Sensors Spatial Information Science, 8, 1413–1416. https:\u002F\u002Fdoi.org\u002F10.5194\u002Fisprsarchives-XL-8-1413-2014\nZhang, J. C., Liang Pu, R., Hua Wang, J., Jiang Huang, W., Yuan, L., & Hua Luo, J. (2012). Detecting powdery mildew of winter wheat using leaf level hyperspectral measurements. Computer Electronics Agriculture, 85, 13–23.\nZhang, J. C., Yuan, L., Wang, J. H., Huang, W. J., Chen, L. P., & Zhang, D. Y. (2012). Spectroscopic leaf level detection of powdery mildew for winter wheat using continuous wavelet analysis. Journal of Integrative Agriculture, 11, 1474–1484.\nCao, X., Luo, Y., Zhou, Y., Fan, J., Xu, X., West, J. S., Duan, X., & Cheng, D. (2015). Detection of powdery mildew in two winter wheat plant densities and prediction of grain yield using canopy hyperspectral reflectance. PLoS ONE, 10, 1–14.\nYu, K., Anderegg, J., Mikaberidze, A., Karisto, P., Mascher, F., McDonald, B. A., Walter, A., & Hund, A. (2018). Hyperspectral canopy sensing of wheat septoria tritici blotch disease. Frontiers in Plant Science, 9, 1–17.\nYuan, L., Huang, Y., Loraamm, R. W., Nie, C., Wang, J., & Zhang, J. (2014). Spectral analysis of winter wheat leaves for detection and differentiation of diseases and insects. Food Crop Research, 156, 199–207. https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.fcr.2013.11.012\nLeufen, G., Noga, G., Hunsche, M., Leufen, G., Noga, G., & Hunsche, M. (2014). Proximal sensing of plant-pathogen interactions in spring barley with three fluorescence techniques. Sensors, 14, 11135–11152.\nRolfe, S. A., & Scholes, J. D. (2010). Chlorophyll fluorescence imaging of plant-pathogen interactions. Protoplasma, 247, 163–175.\nSikorska, E., Khmelinskii, I. V., Sikorski, M., Caponio, F., Bilancia, M. T., Pasqualone, A., & Gomes, T. (2008). Fluorescence spectroscopy in monitoring of extra virgin olive oil during storage. International Journal of Food Science and Technology, 43, 52–61.\nEitenmiller, R. R., Ye, L., & Landen, W. O. (2008). Vitamin analysis for the health and food sciences (2nd ed., pp. 119–191). CRC Press.\nSikorska, E., Khmelinskii, I., & Sikorski, M. (2012). Olive oil—Constituents, quality, health properties and bioconversions (pp. 63–88). InTech. https:\u002F\u002Fdoi.org\u002F10.5772\u002F30676\nKaroui, R., Cartaud, G., & Dufour, E. (2006). Front-face fluorescence spectroscopy as a rapid and nondestructive tool for differentiating various cereal products: A preliminary investigation. Journal of Agriculture and Food Chemistry, 54, 2027–2034.\nTena, N., García-gonzález, D. L., & Aparicio, R. (2009). Evaluation of virgin olive oil thermal deterioration by fluorescence spectroscopy. Journal of Agriculture and Food Chemistry, 57, 10505–10511.\nTříska, J., Vrchotová, N., Olejníčková, J., Jílek, R., & Sotolář, R. (2012). Separation and identification of highly fluorescent compounds derived from trans-resveratrol in the leaves of Vitis vinifera infected by Plasmopara viticola. Molecules, 17, 2773–2783.\nTalamond, P., Verdeil, J. L., & Conéjéro, G. (2015). Secondary metabolite localization by autofluorescence in living plant cells. Molecules, 20, 5024–5037.\nGarcía-Plazaola, J. I., Fernández-Marín, B., Duke, S. O., Hernández, A., López-Arbeloa, F., & Becerril, J. M. (2015). Autofluorescence: Biological functions and technical applications (Supplementary Table 1). Plant Science, 236, 136–145.\nChappelle, E. W., McMurtrey, J. E., & Kim, M. S. (1991). Identification of the pigment responsible for the blue fluorescence band in the laser induced fluorescence (LIF) spectra of green plants, and the potential use of this band in remotely estimating rates of photosynthesis. Remote Sensing of Environment, 36, 213–218.\nMorales, F., Cartelat, A., Álvarez-Fernández, A., Moya, I., & Cerovic, Z. G. (2005). Time-resolved spectral studies of blue-green fluorescence of artichoke (Cynara cardunculus L. var. Scolymus) leaves: Identification of chlorogenic acid as one of the major fluorophores and age-mediated changes. Journal of Agriculture Food Chemistry, 53, 9668–9678.\nFulcher, R. G., O’Brien, T. P., & Lee, J. W. (1972). Studies on the aleurone layer I. Conventional and fluorescence microscopy of the cell wall with emphasis on phenol-carbohydrate complexes in wheat. Australian Journal of Biology Science, 25, 23–34.\nDonaldson, L., & Williams, N. (2018). Imaging and spectroscopy of natural fluorophores in pine needles. Plants, 7, 1–16. https:\u002F\u002Fdoi.org\u002F10.3390\u002Fplants7010010\nOros, C. L., & Alves, F. (2018). Leaf wound induced ultraweak photon emission is suppressed under anoxic stress: Observations of Spathiphyllum under aerobic and anaerobic conditions using novel in vivo methodology. PLoS ONE, 13, e0198962.\nBirtic, S., Ksas, B., Genty, B., Mueller, M. J., Triantaphylidès, C., & Havaux, M. (2011). Using spontaneous photon emission to image lipid oxidation patterns in plant tissues. The Plant Journal, 67, 1103–1115.\nCerovic, Z. G., Langrand, E., Latouche, G., Morales, F., & Moya, I. (1998). Spectral characterization of NAD(P)H fluorescence in intact isolated chloroplasts and leaves: Effect of chlorophyll concentration on reabsorption of blue-green fluorescence. Photosynthesis Research, 56, 291–301.\nBelefant-Miller, H., Miller, G. H., & Rutger, J. N. (2005). Nondestructive measurement of carotenoids in plant tissues by fluorescence quenching. Crop Science, 45, 1786–1789.\nStober, F., Lang, M., & Lichtenthaler, H. K. (1994). Blue, green, and red fluorescence emission signatures of green, etiolated, and white leaves. Remote Sensing of Environment, 47, 65–71.\nGottwald, T. R. (2010). Current epidemiological understanding of citrus Huanglongbing. Annual Review of Phytopathology, 48, 119–139.",{"VOID":1184},"10.1007\u002Fs43630-022-00303-2","2024-05-12T04:07:11.123+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs43630-022-00303-2",[1188,1203,1218,1233,1248],{"id":1189,"sortIndex":21,"researcher":20,"roles":1190,"affiliations":1191,"properties":1200,"displayName":1202,"givenName":20,"familyName":20},"408e750a-6333-434c-a745-b226abcf1f4a",[201],[1192],{"id":1193,"sortIndex":21,"affiliation":1194,"properties":20},"e56f2543-ddf6-4162-8458-93c08459cb5f",{"id":1193,"createTime":20,"updateTime":20,"relativeEntities":1195,"slug":20,"properties":1196,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1199,"statistic":20},[],{"title":1197},{"VI":1198},"Agriculture and Biophotonics Division, National Institute of Lasers and Optronics College, Pakistan Institute of Engineering and Applied Sciences, Islamabad, Pakistan",[],{"title":1201},{"VI":1202},"Babar Manzoor Atta",{"id":1204,"sortIndex":145,"researcher":20,"roles":1205,"affiliations":1206,"properties":1213,"displayName":1215,"givenName":20,"familyName":20},"6ef112e6-1bcb-40a6-87cc-847a8c4f4b98",[201],[1207],{"id":1193,"sortIndex":21,"affiliation":1208,"properties":20},{"id":1193,"createTime":20,"updateTime":20,"relativeEntities":1209,"slug":20,"properties":1210,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1212,"statistic":20},[],{"title":1211},{"VI":1198},[],{"title":1214,"gsAuthor":1216},{"VI":1215},"M. Saleem",{"VOID":1217},"[\"w1CvX2MAAAAJ\"]",{"id":1219,"sortIndex":231,"researcher":20,"roles":1220,"affiliations":1221,"properties":1228,"displayName":1230,"givenName":20,"familyName":20},"c4f721ae-062a-4b46-bf4e-b1e20a5db9de",[201],[1222],{"id":1193,"sortIndex":21,"affiliation":1223,"properties":20},{"id":1193,"createTime":20,"updateTime":20,"relativeEntities":1224,"slug":20,"properties":1225,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1227,"statistic":20},[],{"title":1226},{"VI":1198},[],{"title":1229,"gsAuthor":1231},{"VI":1230},"M. Bilal",{"VOID":1232},"[\"x35CFikAAAAJ\"]",{"id":1234,"sortIndex":474,"researcher":20,"roles":1235,"affiliations":1236,"properties":1243,"displayName":1245,"givenName":20,"familyName":20},"0fd1fae6-1cd2-4075-b100-8f2ef132e5e5",[201],[1237],{"id":1193,"sortIndex":21,"affiliation":1238,"properties":20},{"id":1193,"createTime":20,"updateTime":20,"relativeEntities":1239,"slug":20,"properties":1240,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1242,"statistic":20},[],{"title":1241},{"VI":1198},[],{"title":1244,"gsAuthor":1246},{"VI":1245},"Aziz ul Rehman",{"VOID":1247},"[\"8fJX2SkAAAAJ\"]",{"id":1249,"sortIndex":945,"researcher":20,"roles":1250,"affiliations":1251,"properties":1260,"displayName":1262,"givenName":20,"familyName":20},"e9320cce-9837-4b79-bceb-53ccd4e9d76a",[201],[1252],{"id":1253,"sortIndex":21,"affiliation":1254,"properties":20},"9bc4f1b6-da42-4727-9a5f-323d71bd72db",{"id":1253,"createTime":20,"updateTime":20,"relativeEntities":1255,"slug":20,"properties":1256,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1259,"statistic":20},[],{"title":1257},{"VI":1258},"Crop Diseases Research Institute (CDRI), National Agricultural Research Centre (NARC), Islamabad, Pakistan",[],{"title":1261},{"VI":1262},"M. Fayyaz",{"url":20,"publisher":1264,"properties":20},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1265,"slug":10,"properties":1266,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1269,"manageAffiliations":1274,"indexDatabases":1285,"url":20,"thumbnailPath":20,"statistic":1300,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":1267,"title":1268},{"VOID":13},{"EN":15},[1270],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":1271,"label":1272,"description":1273,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[1275,1280],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":1276,"slug":20,"properties":1277,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1279,"statistic":20},[],{"title":1278},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":1281,"slug":20,"properties":1282,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1284,"statistic":20},[],{"title":1283},{"EN":43},[37],[1286,1293],{"id":47,"indexDatabase":1287,"url":58,"indexYears":59,"academicFieldIds":1292,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":1288,"label":1289,"description":1290,"key":55,"publicationTags":1291,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":1294,"url":77,"indexYears":20,"academicFieldIds":1299,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":1295,"label":1296,"description":1297,"key":73,"publicationTags":1298,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":1301,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":1302,"totalCitation":121,"totalCitationByYear":1303,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":1304,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"total":21,"publishYear":1306,"statisticByYear":1307},2022,{},"2022-09-19",[62,75],{"id":1311,"createTime":1312,"updateTime":1313,"relativeEntities":1314,"slug":1315,"properties":1316,"entityType":192,"verifyStatus":193,"verifyTime":1325,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":1326,"fullTextUrl":20,"authors":1327,"publicationType":245,"publisherRelationship":1373,"citationCount":21,"citationInfo":1420,"publishDate":1423,"publishYear":1421,"citationAnalyzeStatus":19,"lastCitationAnalyze":1424,"indexDatabases":1425,"openAccess":20,"references":1426,"isForceReanalyzing":412},"e363fd94-fda1-4a34-8027-a0bb1e42cb5a","2024-01-26T15:44:33.856+00:00","2026-07-22T12:48:59.682+00:00",[],"Solving-the-structure-of-plant-photosystem-I-biochemistry-is-vital",{"abstract":1317,"title":1319,"gsPaper":1321,"doi":1323},{"EN":1318},"The recently determined structure of plant photosystem I (PSI) provides the first relatively high-resolution structural model of a supercomplex containing a reaction center and its peripheral antenna. Large amounts of highly purified PSI were required to get enough crystals amenable for structural determination by X-ray crystallography. In addition, a deep biochemical understanding of the large supercomplex was vital for achieving the goal. The stability of PSI was analyzed by sucrose gradient centrifugation and gel electrophoresis. Small amounts of LHCI were detached from PSI following a 12 day incubation under crystallization conditions. The interaction between the reaction center and the peripheral antenna of PSI (LHCI) as well as the interactions among the LHCI monomers are flexible. Nevertheless, the pure and homogeneous preparation of PSI allows for relatively tight crystal packing, which holds promise for obtaining atomic resolution in the future.",{"EN":1320},"Solving the structure of plant photosystem I—biochemistry is vital",{"VOID":1322},"[\"1415550977845599495\"]",{"VOID":1324},"10.1039\u002Fb506132f","2024-04-29T06:42:56.797+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1039\u002Fb506132f",[1328,1345,1358],{"id":1329,"sortIndex":21,"researcher":20,"roles":1330,"affiliations":1331,"properties":1340,"displayName":1342,"givenName":20,"familyName":20},"0d6deab4-4e21-455b-9893-67a855cbbde8",[201],[1332],{"id":1333,"sortIndex":21,"affiliation":1334,"properties":20},"5898b5d0-c245-483b-8453-ec2866ff5bdb",{"id":1333,"createTime":20,"updateTime":20,"relativeEntities":1335,"slug":20,"properties":1336,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1339,"statistic":20},[],{"title":1337},{"VI":1338},"Department of Biochemistry, The George S. Wise Faculty of Life Sciences, The Daniella Rich Institute for Structural Biology, Tel Aviv University, Tel Aviv, Israel",[],{"title":1341,"gsAuthor":1343},{"VI":1342},"Alexey Amunts",{"VOID":1344},"[\"xuCj4F8AAAAJ\"]",{"id":1346,"sortIndex":145,"researcher":20,"roles":1347,"affiliations":1348,"properties":1355,"displayName":1357,"givenName":20,"familyName":20},"65272007-c4c2-405b-826a-c8e7b3d0201f",[201],[1349],{"id":1333,"sortIndex":21,"affiliation":1350,"properties":20},{"id":1333,"createTime":20,"updateTime":20,"relativeEntities":1351,"slug":20,"properties":1352,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1354,"statistic":20},[],{"title":1353},{"VI":1338},[],{"title":1356},{"VI":1357},"Adam Ben-Shem",{"id":1359,"sortIndex":231,"researcher":20,"roles":1360,"affiliations":1361,"properties":1368,"displayName":1370,"givenName":20,"familyName":20},"e7b2a1d1-f3cb-4813-9aea-850716ac8953",[201],[1362],{"id":1333,"sortIndex":21,"affiliation":1363,"properties":20},{"id":1333,"createTime":20,"updateTime":20,"relativeEntities":1364,"slug":20,"properties":1365,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1367,"statistic":20},[],{"title":1366},{"VI":1338},[],{"title":1369,"gsAuthor":1371},{"VI":1370},"Nathan Nelson",{"VOID":1372},"[\"yNrdRDIAAAAJ\"]",{"url":1326,"publisher":1374,"properties":1415},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1375,"slug":10,"properties":1376,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1379,"manageAffiliations":1384,"indexDatabases":1395,"url":20,"thumbnailPath":20,"statistic":1410,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":1377,"title":1378},{"VOID":13},{"EN":15},[1380],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":1381,"label":1382,"description":1383,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[1385,1390],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":1386,"slug":20,"properties":1387,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1389,"statistic":20},[],{"title":1388},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":1391,"slug":20,"properties":1392,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1394,"statistic":20},[],{"title":1393},{"EN":43},[37],[1396,1403],{"id":47,"indexDatabase":1397,"url":58,"indexYears":59,"academicFieldIds":1402,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":1398,"label":1399,"description":1400,"key":55,"publicationTags":1401,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":1404,"url":77,"indexYears":20,"academicFieldIds":1409,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":1405,"label":1406,"description":1407,"key":73,"publicationTags":1408,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":1411,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":1412,"totalCitation":121,"totalCitationByYear":1413,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":1414,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"pages":1416,"volume":1418},{"VOID":1417},"1011-1015",{"VOID":1419},"4",{"total":21,"publishYear":1421,"statisticByYear":1422},2005,{},"2005-12-01","2026-07-22T12:48:59.681+00:00",[62,75],[1427,1430,1433,1436,1439,1445,1448,1451,1454,1457,1460,1463,1466,1469,1472,1475,1478,1481,1484,1487,1490,1493],{"id":305,"text":1428,"url":307,"identifiers":1429},"J. Barber, Photosystem II: a multisubunit membrane protein that oxidises water Curr. Opin. Struct. Biol. 2002 12 523–530",{"doi":309},{"id":305,"text":1431,"url":307,"identifiers":1432},"N. Nelson, A. Ben-Shem The complex architecture of oxygenic photosynthesis Nat. Rev. Mol. Cell Biol. 2004 5 971–982",{"doi":309},{"id":305,"text":1434,"url":307,"identifiers":1435},"B. Kok, Absorption changes induced by the photochemical reaction of photosynthesis Nature 1957 179 583–584",{"doi":309},{"id":305,"text":1437,"url":307,"identifiers":1438},"B. Kok, Partial purification and determination of oxidation-reduction potential of the photosynthetic chlorophyll complex absorbing at 700 nm Biochim. Biophys. Acta 1961 48 527–533",{"doi":309},{"id":1440,"text":1441,"url":1442,"identifiers":1443},"f8f917a8-60e4-469c-8161-805616045597","C. Bengis and N. Nelson, Purification and properties of the photosystem I reaction center from chloroplasts J. Biol. Chem. 1975 250 2783–2788","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS0021925819415585",{"doi":1444},"10.1016\u002FS0021-9258(19)41558-5",{"id":305,"text":1446,"url":307,"identifiers":1447},"C. Bengis and N. Nelson, Subunit structure of chloroplast photosystem I reaction center J. Biol. Chem. 1977 252 4564–4569",{"doi":309},{"id":305,"text":1449,"url":307,"identifiers":1450},"H. V. Scheller, P. E. Jensen, A. Haldrup, C. Lunde and J. Knoetzel, Role of subunits in eukaryotic Photosystem I Biochim. Biophys. Acta 2001 1507 41–60",{"doi":309},{"id":305,"text":1452,"url":307,"identifiers":1453},"P. E. Jensen, A. Haldrup, L. Rosgaard and H. V. Scheller, Molecular dissection of photosystem I in higher plants: topology, structure and function Physiol. Plant, 2003 119 313–321",{"doi":309},{"id":20,"text":1455,"url":20,"identifiers":1456},"J. E. Mullet, J. J. Burke and C. J. Arntzen, Chlorophyll proteins of photosystem I Plant Physiol. 1980 65 814–822",{},{"id":305,"text":1458,"url":307,"identifiers":1459},"R. Bassi and D. Simpson, Chlorophyll-protein complexes of barley photosystem I Eur. J. Biochem. 1987 163 221–230",{"doi":309},{"id":305,"text":1461,"url":307,"identifiers":1462},"R. Croce, T. Morosinotto, S. Castelletti, J. Breton and R. Bassi, The Lhca antenna complexes of higher plants photosystem I Biochim. Biophys. Acta 2002 1556 29–40",{"doi":309},{"id":305,"text":1464,"url":307,"identifiers":1465},"N. Nelson, A. Ben-Shem Photosystem I reaction center: Past and future Photosynth. Res. 2002 73 193–206",{"doi":309},{"id":305,"text":1467,"url":307,"identifiers":1468},"A. Ben-Shem, N. Nelson and F. Frolow, Crystallization and initial X-ray diffraction studies of higher plant photosystem I Acta Crystallogr., Sect. D: Biol. Crystallogr. 2003 D59 1824–1827",{"doi":309},{"id":20,"text":1470,"url":20,"identifiers":1471},"A. Ben-Shem, F. Frolow and N. Nelson, The crystal structure of plant photosystem I Nature 2003 426 630–635",{},{"id":20,"text":1473,"url":20,"identifiers":1474},"N. Nelson and A. Ben-Shem, in Photosystem I. Structure, Function and Regulation of Plant Photosystem I, ed. J. H. Golbeck, Kluwer academic publishing, Dordrecht, 2005, in press",{},{"id":20,"text":1476,"url":20,"identifiers":1477},"D. I. Arnon, Copper enzymes in isolated chloroplasts. Polyphenoloxidase in Beta vulgaris Plant Physiol. 1949 24 1–15",{},{"id":305,"text":1479,"url":307,"identifiers":1480},"S. Zhang and H. V. Scheller, Light-harvesting complex II binds to several small subunits of photosystem I J. Biol. Chem. 2004 279 3180–3187",{"doi":309},{"id":305,"text":1482,"url":307,"identifiers":1483},"A. Ben-Shem, F. Frolow and N. Nelson, Evolution of Photosystem I - from Symmetry through Pseudosymmetry to Asymmetry FEBS Lett. 2004 564 274–280",{"doi":309},{"id":305,"text":1485,"url":307,"identifiers":1486},"A. Ben-Shem, F. Frolow and N. Nelson, Light-harvesting features revealed by the structure of plant photosystem I Photosynth. Res. 2004 81 239–250",{"doi":309},{"id":305,"text":1488,"url":307,"identifiers":1489},"C. P. Lunde, P. E. Jensen, A. Haldrup, J. Knoetzel and H. V. Scheller, The PSI-H subunit of photosystem I is essential for state transitions in plant photosynthesis Nature 2000 408 613–615",{"doi":309},{"id":305,"text":1491,"url":307,"identifiers":1492},"A. Haldrup, H. Naver and H. V. Scheller, The interaction between plastocyanin and photosystem I is inefficient in transgenic Arabidopsis plants lacking the PSI-N subunit of photosystem I Plant J. 1999 17 689–698",{"doi":309},{"id":305,"text":1494,"url":307,"identifiers":1495},"J. Knoetzel, A. Mant, A. Haldrup, P. E. Jensen and H. V. Scheller, PSI-O, a new 10-kDa subunit of eukaryotic photosystem I FEBS Lett. 2002 510 145–148*-*- *-*-*-",{"doi":309},{"id":1497,"createTime":1498,"updateTime":1499,"relativeEntities":1500,"slug":1501,"properties":1502,"entityType":192,"verifyStatus":193,"verifyTime":1514,"verifyNote":195,"languages":1515,"translateLanguages":20,"viewCount":21,"primaryUrl":1516,"fullTextUrl":20,"authors":1517,"publicationType":245,"publisherRelationship":1592,"citationCount":1641,"citationInfo":1642,"publishDate":1647,"publishYear":1643,"citationAnalyzeStatus":1015,"lastCitationAnalyze":1499,"indexDatabases":1648,"openAccess":20,"references":1649,"isForceReanalyzing":412},"2c2ca80e-a363-4d66-815d-28665fc718d3","2024-04-18T21:40:55.732+00:00","2026-07-22T12:41:21.804+00:00",[],"Role-of-solute-solvent-hydrogen-bonds-on-the-ground-state-and-the-excited-state-proton-transfer-in-3-hydroxyflavone-A-systematic-spectrophotometry-study",{"openalex":1503,"mag":1505,"title":1507,"gsPaper":1509,"pm":1510,"doi":1512},{"VOID":1504},"W2805983671",{"VOID":1506},"2805983671",{"EN":1508},"Role of solute-solvent hydrogen bonds on the ground state and the excited state proton transfer in 3-hydroxyflavone. A systematic spectrophotometry study",{"VOID":862},{"VOID":1511},"33856683",{"VOID":1513},"10.1039\u002Fc8pp00053k","2024-06-25T19:01:28.434+00:00",[634],"https:\u002F\u002Flink.springer.com\u002F10.1039\u002Fc8pp00053k",[1518,1537,1554,1573],{"id":1519,"sortIndex":21,"researcher":20,"roles":1520,"affiliations":1521,"properties":1530,"displayName":1534,"givenName":20,"familyName":20},"c49bffb9-0078-46b4-97cb-251375a5b0a8",[],[1522],{"id":1523,"sortIndex":21,"affiliation":1524,"properties":20},"d36ee405-aee8-40cc-9899-523f9c77ae98",{"id":1523,"createTime":20,"updateTime":20,"relativeEntities":1525,"slug":20,"properties":1526,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1529,"statistic":20},[],{"title":1527},{"EN":1528},"Radchem Lab, Department of Chemistry, University of Pavia, Via Taramelli 10, Italy",[],{"orcid":1531,"title":1533,"openalex":1535},{"VOID":1532},"https:\u002F\u002Forcid.org\u002F0000-0001-7154-3932",{"EN":1534},"Simone Lazzaroni",{"VOID":1536},"A5024009042",{"id":1538,"sortIndex":145,"researcher":20,"roles":1539,"affiliations":1540,"properties":1547,"displayName":1551,"givenName":20,"familyName":20},"88591e63-2339-4993-9373-052f79762b43",[],[1541],{"id":1523,"sortIndex":21,"affiliation":1542,"properties":20},{"id":1523,"createTime":20,"updateTime":20,"relativeEntities":1543,"slug":20,"properties":1544,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1546,"statistic":20},[],{"title":1545},{"EN":1528},[],{"orcid":1548,"title":1550,"openalex":1552},{"VOID":1549},"https:\u002F\u002Forcid.org\u002F0000-0001-6635-4467",{"EN":1551},"Daniele Dondi",{"VOID":1553},"A5014358252",{"id":1555,"sortIndex":231,"researcher":20,"roles":1556,"affiliations":1557,"properties":1566,"displayName":1570,"givenName":20,"familyName":20},"efd13ccf-3a5a-4cae-9894-fe39cd78e184",[],[1558],{"id":1559,"sortIndex":21,"affiliation":1560,"properties":20},"ac414b8e-b7bc-492b-abe7-d6bfe699d3f5",{"id":1559,"createTime":20,"updateTime":20,"relativeEntities":1561,"slug":20,"properties":1562,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1565,"statistic":20},[],{"title":1563},{"EN":1564},"Laboratoire de Réactivité de Surface UMR CNRS 7197, Sorbonne Université, Faculté de Sciences et Ingénierie, Tour 43-53, 3ème étage, 4 Pl Jussieu, 75005, Paris, France",[],{"orcid":1567,"title":1569,"openalex":1571},{"VOID":1568},"https:\u002F\u002Forcid.org\u002F0000-0002-8990-916X",{"EN":1570},"Alberto Mezzetti",{"VOID":1572},"A5031278685",{"id":1574,"sortIndex":474,"researcher":20,"roles":1575,"affiliations":1576,"properties":1585,"displayName":1589,"givenName":20,"familyName":20},"aa11a61f-4d2c-48e1-8d8b-c268b9ede3df",[],[1577],{"id":1578,"sortIndex":21,"affiliation":1579,"properties":20},"51d718ec-9d93-4706-830f-d63145d1fa97",{"id":1578,"createTime":20,"updateTime":20,"relativeEntities":1580,"slug":20,"properties":1581,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1584,"statistic":20},[],{"title":1582},{"EN":1583},"PhotoGreen Lab, Department of Chemistry, University of Pavia, Via Taramelli 12, 27100, Pavia, Italy",[],{"orcid":1586,"title":1588,"openalex":1590},{"VOID":1587},"https:\u002F\u002Forcid.org\u002F0000-0002-5313-5692",{"EN":1589},"Stefano Protti",{"VOID":1591},"A5053028910",{"url":20,"publisher":1593,"properties":1634},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1594,"slug":10,"properties":1595,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":1598,"manageAffiliations":1603,"indexDatabases":1614,"url":20,"thumbnailPath":20,"statistic":1629,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":1596,"title":1597},{"VOID":13},{"EN":15},[1599],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":1600,"label":1601,"description":1602,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[1604,1609],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":1605,"slug":20,"properties":1606,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1608,"statistic":20},[],{"title":1607},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":1610,"slug":20,"properties":1611,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1613,"statistic":20},[],{"title":1612},{"EN":43},[37],[1615,1622],{"id":47,"indexDatabase":1616,"url":58,"indexYears":59,"academicFieldIds":1621,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":1617,"label":1618,"description":1619,"key":55,"publicationTags":1620,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":1623,"url":77,"indexYears":20,"academicFieldIds":1628,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":1624,"label":1625,"description":1626,"key":73,"publicationTags":1627,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":1630,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":1631,"totalCitation":121,"totalCitationByYear":1632,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":1633,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"issue":1635,"pages":1637,"volume":1639},{"VOID":1636},"7",{"VOID":1638},"923-933",{"VOID":1640},"17",29,{"total":1641,"publishYear":1643,"statisticByYear":1644},2018,{"2018":145,"2019":1645,"2020":1646,"2021":1645,"2022":1646,"2023":1646,"2024":145},6,5,"2018-07-01",[62,75],[1650,1654,1657,1661,1665,1669,1673,1677,1681,1685,1689,1693,1697,1701,1705,1709,1713,1717,1721,1725,1729,1733,1737,1741,1745,1749,1753,1757,1761,1765,1769,1773,1777,1781,1785,1789,1793,1797,1801,1805,1809,1813,1817,1821,1825,1828,1832,1836,1840,1844,1848,1852,1856,1859,1863,1867,1871,1875,1879,1883,1887,1890,1894,1898,1901,1905,1909,1913],{"id":20,"text":1651,"url":20,"identifiers":1652},"A. S. Klymchenko, Acc. Chem. Res., 2017, 50, 366–375.",{"doi":1653},"10.1021\u002Facs.accounts.6b00517",{"id":20,"text":1655,"url":20,"identifiers":1656},"P. K. Sengupta, Reviews in Fluorescence, 2016, pp. 45–70.",{},{"id":20,"text":1658,"url":20,"identifiers":1659},"A. S. Klymchenko and Y. Mely, Prog. Mol. Biol. Transl. Sci., 2013, 113, 35–58.",{"doi":1660},"10.1016\u002FB978-0-12-386932-6.00002-8",{"id":20,"text":1662,"url":20,"identifiers":1663},"S. Protti and A. Mezzetti, Photochemistry, 2012, 40, 295–322.",{"doi":1664},"10.1039\u002F9781849734882-00295",{"id":20,"text":1666,"url":20,"identifiers":1667},"P. K. Sengupta and M. Kasha, Chem. Phys. Lett., 1979, 68, 382–385.",{"doi":1668},"10.1016\u002F0009-2614(79)87221-8",{"id":20,"text":1670,"url":20,"identifiers":1671},"D. McMorrow and M. Kasha, J. Phys. Chem., 1984, 88, 2235–2243.",{"doi":1672},"10.1021\u002Fj150655a012",{"id":20,"text":1674,"url":20,"identifiers":1675},"R. Lehnig, D. Pentlehner, A. Vdovin, B. Dick and A. Slenczka, J. Chem. Phys., 2009, 131, 194307.",{"doi":1676},"10.1063\u002F1.3262707",{"id":20,"text":1678,"url":20,"identifiers":1679},"A. N. Bader, F. Ariese and C. Gooijer, J. Phys. Chem. A, 2002, 106, 2844–2849.",{"doi":1680},"10.1021\u002Fjp013840o",{"id":20,"text":1682,"url":20,"identifiers":1683},"A. J. G. Strandjord and P. F. Barbara, J. Phys. Chem., 1985, 89, 2355–2361.",{"doi":1684},"10.1021\u002Fj100257a041",{"id":20,"text":1686,"url":20,"identifiers":1687},"G. A. Brucker, T. C. Swinney and D. F. Kelley, J. Phys. Chem., 1991, 95, 3190–3195.",{"doi":1688},"10.1021\u002Fj100161a043",{"id":20,"text":1690,"url":20,"identifiers":1691},"V. I. Tomin, in Hydrogen Bonding and Transfer in the Excited State ed. K.-L. Han and G.-J. Zhao, John Wiley & Sons, Ltd., Chichester, UK, 2010, vol. I & II, pp. 463–523, DOI: 10.1002\u002F9780470669143.ch22.",{"doi":1692},"10.1002\u002F9780470669143.ch22",{"id":20,"text":1694,"url":20,"identifiers":1695},"B. Dereka, R. Letrun, D. Svechkarev, A. Rosspeintner and E. Vauthey, J. Phys. Chem. B, 2014, 119, 2434–2443.",{"doi":1696},"10.1021\u002Fjp507311n",{"id":20,"text":1698,"url":20,"identifiers":1699},"S. Das and N. Chattopadhyay, ChemistrySelect, 2017, 2, 6078–6081.",{"doi":1700},"10.1002\u002Fslct.201701401",{"id":20,"text":1702,"url":20,"identifiers":1703},"S. A. Ahmed, B. Maity, S. Seth and D. Seth, J. Photochem. Photobiol., B, 2017, 168, 132–141.",{"doi":1704},"10.1016\u002Fj.jphotobiol.2017.02.006",{"id":20,"text":1706,"url":20,"identifiers":1707},"S. Protti, A. Mezzetti, J.-P. Cornard, C. Lapouge and M. Fagnoni, Chem. Phys. Lett., 2008, 467, 88–93.",{"doi":1708},"10.1016\u002Fj.cplett.2008.11.005",{"id":20,"text":1710,"url":20,"identifiers":1711},"A. Douhal, M. Sanz, L. Tormo and J. A. Organero, ChemPhysChem, 2005, 6, 419–423.",{"doi":1712},"10.1002\u002Fcphc.200400375",{"id":20,"text":1714,"url":20,"identifiers":1715},"P. K. Mandal and A. Samanta, J. Phys. Chem. A, 2003, 107, 6334–6339.",{"doi":1716},"10.1021\u002Fjp027613d",{"id":20,"text":1718,"url":20,"identifiers":1719},"D. A. Parthenopoulos and M. Kasha, Chem. Phys. Lett., 1990, 173, 303–309.",{"doi":1720},"10.1016\u002F0009-2614(90)85274-G",{"id":20,"text":1722,"url":20,"identifiers":1723},"S. Protti and A. Mezzetti, J. Mol. Liq., 2015, 205, 110–114.",{"doi":1724},"10.1016\u002Fj.molliq.2014.12.001",{"id":20,"text":1726,"url":20,"identifiers":1727},"S. Protti, A. Mezzetti, C. Lapouge and J.-P. Cornard, Photochem. Photobiol. Sci., 2008, 7, 109–119.",{"doi":1728},"10.1039\u002FB709682H",{"id":20,"text":1730,"url":20,"identifiers":1731},"S. L. Studer, W. E. Brewer, M. L. Martinez and P.-T. Chou, J. Am. Chem. Soc., 1989, 111, 7643–7644.",{"doi":1732},"10.1021\u002Fja00201a071",{"id":20,"text":1734,"url":20,"identifiers":1735},"Z. Szakács, M. Kállay and M. Kubinyi, RSC Adv., 2017, 7, 32185–32192.",{"doi":1736},"10.1039\u002FC7RA04590E",{"id":20,"text":1738,"url":20,"identifiers":1739},"M. Musialik, R. Kuzmicz, T. S. Pawlowski and G. Litwinienko, J. Org. Chem., 2009, 74, 2699–2709.",{"doi":1740},"10.1021\u002Fjo802716v",{"id":20,"text":1742,"url":20,"identifiers":1743},"P. Chou, D. McMorrow, T. J. Aartsma and M. Kasha, J. Phys. Chem., 1984, 88, 4596–4599.",{"doi":1744},"10.1021\u002Fj150664a032",{"id":20,"text":1746,"url":20,"identifiers":1747},"S. Protti, K. Raulin, O. Cristini, C. Kinowski, S. Turrell and A. Mezzetti, J. Mol. Struct., 2011, 993, 485–490.",{"doi":1748},"10.1016\u002Fj.molstruc.2011.02.010",{"id":20,"text":1750,"url":20,"identifiers":1751},"E. Biagtan, E. Goldberg, R. Stephens, E. Valeroso and J. Harmon, Nucl. Instrum. Methods Phys. Res., Sect. B, 1996, 114, 88–90.",{"doi":1752},"10.1016\u002F0168-583X(96)00135-8",{"id":20,"text":1754,"url":20,"identifiers":1755},"F. J. Aparicio, M. Alcaire, A. R. González-Elipe, A. Barranco, M. Holgado, R. Casquel, F. J. Sanz, A. Griol, D. Bernier, F. Dortu, S. Cáceres, M. Antelius, M. Lapis, H. Sohlström and F. Niklaus, Sens. Actuators, B, 2016, 228, 649–657.",{"doi":1756},"10.1016\u002Fj.snb.2016.01.092",{"id":20,"text":1758,"url":20,"identifiers":1759},"F. J. Aparicio, M. Alcaire, A. Borras, J. C. Gonzalez, F. López-Arbelo, I. Blasczcyk-Lezak, A. R. González-Elipe and A. Barranco, J. Mater. Chem. C, 2014, 2, 6561–6573.",{"doi":1760},"10.1039\u002FC4TC00294F",{"id":20,"text":1762,"url":20,"identifiers":1763},"E. Karakus, M. Uçuncu and M. Emrullahoglu, Anal. Chem., 2016, 88, 1039–1043.",{"doi":1764},"10.1021\u002Facs.analchem.5b04163",{"id":20,"text":1766,"url":20,"identifiers":1767},"F. S. Santos, E. Ramasamy, V. Ramamurthy and F. S. Rodembusch, Photochem. Photobiol. Sci., 2014, 13, 992–996.",{"doi":1768},"10.1039\u002FC4PP00096J",{"id":20,"text":1770,"url":20,"identifiers":1771},"A. Capan, M. S. Bostan, E. Mozioglu, M. Akoz, A. C. Goren, M. S. Eroglu and T. Ozturk, J. Photochem. Photobiol., B, 2015, 153, 391–396.",{"doi":1772},"10.1016\u002Fj.jphotobiol.2015.10.019",{"id":20,"text":1774,"url":20,"identifiers":1775},"A. Sytnik and I. Litvinyuk, Proc. Natl. Acad. Sci. U. S. A., 1996, 93, 12959–12963.",{"doi":1776},"10.1073\u002Fpnas.93.23.12959",{"id":20,"text":1778,"url":20,"identifiers":1779},"L. Tormo and A. Douhal, J. Photochem. Photobiol., A, 2005, 173, 358–364.",{"doi":1780},"10.1016\u002Fj.jphotochem.2005.04.015",{"id":20,"text":1782,"url":20,"identifiers":1783},"D. Loco, N. Gelfand, S. Jurinovich, S. Protti, A. Mezzetti and B. Mennucci, J. Phys. Chem. A, 2018, 122, 390–397.",{"doi":1784},"10.1021\u002Facs.jpca.7b10463",{"id":20,"text":1786,"url":20,"identifiers":1787},"S. Hofener, P. C. Kooijman, J. Groen, F. Ariese and L. Visscher, Phys. Chem. Chem. Phys., 2013, 15, 12572–12581.",{"doi":1788},"10.1039\u002Fc3cp44267e",{"id":20,"text":1790,"url":20,"identifiers":1791},"Y. Nishimoto, J. Phys. Chem. A, 2016, 120, 771–784.",{"doi":1792},"10.1021\u002Facs.jpca.5b10732",{"id":20,"text":1794,"url":20,"identifiers":1795},"V. N. Agieienko, Y. V. Kolesnik and O. N. Kalugin, J. Chem. Phys., 2014, 140, 194501.",{"doi":1796},"10.1063\u002F1.4875591",{"id":20,"text":1798,"url":20,"identifiers":1799},"R. Salaeh, C. Prommin, W. Chansen, K. Kerdpol, R. Daengngern and N. Kungwan, J. Mol. Liq., 2018, 252, 428–438.",{"doi":1800},"10.1016\u002Fj.molliq.2017.12.148",{"id":20,"text":1802,"url":20,"identifiers":1803},"M. A. Bellucci and D. F. Coker, J. Chem. Phys., 2012, 136, 194505.",{"doi":1804},"10.1063\u002F1.4707736",{"id":20,"text":1806,"url":20,"identifiers":1807},"V. N. Agieienko and O. N. Kalugin, J. Phys. Chem. B, 2014, 118, 12251–12262.",{"doi":1808},"10.1021\u002Fjp5080829",{"id":20,"text":1810,"url":20,"identifiers":1811},"S. Das, S. Ghosh and N. Chattopadhyay, Chem. Phys. Lett., 2016, 644, 284–287.",{"doi":1812},"10.1016\u002Fj.cplett.2015.12.015",{"id":20,"text":1814,"url":20,"identifiers":1815},"V. I. Tomin and D. U. Ushakou, J. Lumin., 2015, 166, 313–321.",{"doi":1816},"10.1016\u002Fj.jlumin.2015.05.058",{"id":20,"text":1818,"url":20,"identifiers":1819},"V. I. Tomin and D. V. Ushakou, J. Appl. Spectrosc., 2015, 82, 193–199.",{"doi":1820},"10.1007\u002Fs10812-015-0085-0",{"id":20,"text":1822,"url":20,"identifiers":1823},"V. I. Tomin and D. V. Ushakou, J. Lumin., 2016, 178, 94–105.",{"doi":1824},"10.1016\u002Fj.jlumin.2016.05.042",{"id":20,"text":1826,"url":20,"identifiers":1827},"W. L. Whaley, E. M. Okoso-amaa, C. L. Womack, A. Vladimirova, L. B. Rodgers, M. J. Risher and M. H. Abraham, Nat. Prod. Commun., 2012, 7, 1–14.",{},{"id":20,"text":1829,"url":20,"identifiers":1830},"Y. A. Davila, M. I. Sancho, M. C. Almandoz and S. E. Blanco, J. Chem. Eng. Data, 2013, 58, 1706–1716.",{"doi":1831},"10.1021\u002Fje400153r",{"id":20,"text":1833,"url":20,"identifiers":1834},"V. I. Tomin, Opt. Spectrosc., 2012, 113, 41–52.",{"doi":1835},"10.1134\u002FS0030400X12060215",{"id":20,"text":1837,"url":20,"identifiers":1838},"W. Feng, L. Lie, L. Xiang-Ping, Y. Ya-Xin, Z. Gui-Lan and C. Wen-Ju, Chin. Phys. B, 2008, 17, 1461–1466.",{"doi":1839},"10.1088\u002F1674-1056\u002F17\u002F4\u002F052",{"id":20,"text":1841,"url":20,"identifiers":1842},"F. Wu, L. Ma, S. Zhang, Z. Wang and X. Cheng, Mod. Phys. Lett. B, 2015, 29, 1550181.",{"doi":1843},"10.1142\u002FS021798491550181X",{"id":20,"text":1845,"url":20,"identifiers":1846},"V. I. Tomin and R. Jaworski, J. Mol. Struct., 2009, 924, 461–465.",{"doi":1847},"10.1016\u002Fj.molstruc.2008.11.012",{"id":20,"text":1849,"url":20,"identifiers":1850},"V. N. Agieienko, N. A. Ostrohko and O. N. Kalugin, J. Mol. Liq., 2017, 245, 27–34.",{"doi":1851},"10.1016\u002Fj.molliq.2017.05.141",{"id":20,"text":1853,"url":20,"identifiers":1854},"V. Ya. Degoda, V. G. Pivovarenko, I. M. Moroz and D. Yu. Shilov, J. Lumin., 2015, 165, 174–178.",{"doi":1855},"10.1016\u002Fj.jlumin.2015.04.019",{"id":20,"text":1857,"url":20,"identifiers":1858},"W. L. F. Armarego and D. D. Perrin, Purification of Laboratory Chemicals, Reed Educational and Profesional Publishing, 4th edn, 1996, p. 143.",{},{"id":20,"text":1860,"url":20,"identifiers":1861},"A. S. Klymchenko, V. G. Pivovarenko and A. P. Demchenko, Spectrochim. Acta, Part A, 2003, 59, 787–792.",{"doi":1862},"10.1016\u002FS1386-1425(02)00233-0",{"id":20,"text":1864,"url":20,"identifiers":1865},"A. D. Roshal, A. V. Grigorovich, A. O. Doroshenko, V. G. Pivovarenko and A. P. Demchenko, J. Photochem. Photobiol., B, 1999, 127, 89–100.",{"doi":1866},"10.1016\u002FS1010-6030(99)00105-7",{"id":20,"text":1868,"url":20,"identifiers":1869},"M. Voicescu, S. Ionescu and F. Gatea, J. Fluoresc., 2014, 24, 75–83.",{"doi":1870},"10.1007\u002Fs10895-013-1272-0",{"id":20,"text":1872,"url":20,"identifiers":1873},"V. I. Tomin, Opt. Spectrosc., 2011, 110, 550–556.",{"doi":1874},"10.1134\u002FS0030400X11030234",{"id":20,"text":1876,"url":20,"identifiers":1877},"A. S. Klymchenko and A. P. Demchenko, New J. Chem., 2004, 28, 687–692.",{"doi":1878},"10.1039\u002Fb316149h",{"id":20,"text":1880,"url":20,"identifiers":1881},"A. S. Klymchenko, C. Kenfack, G. Duportail and Y. Mely, J. Chem. Sci., 2007, 119, 83–89.",{"doi":1882},"10.1007\u002Fs12039-007-0014-8",{"id":20,"text":1884,"url":20,"identifiers":1885},"A. I. Skilitsi, D. Agathangelou, I. Shulov, J. Conyard, S. Haacke, Y. Mély, A. Klymchenko and J. Léonard, Phys. Chem. Chem. Phys., 2018, 20, 7885–7895.",{"doi":1886},"10.1039\u002FC7CP08584B",{"id":20,"text":1888,"url":20,"identifiers":1889},"C. Reichardt, Solvents and Solvent Effects in Organic Chemistry, 3rd edn, Wiley, 2004.",{},{"id":20,"text":1891,"url":20,"identifiers":1892},"M. J. Kamlet, J. L. M. Abboud, M. H. Abraham and R. W. Taft, J. Org. Chem., 1983, 48, 2877–2887.",{"doi":1893},"10.1021\u002Fjo00165a018",{"id":20,"text":1895,"url":20,"identifiers":1896},"M. H. Abraham, Chem. Soc. Rev., 1993, 22, 73–83.",{"doi":1897},"10.1039\u002Fcs9932200073",{"id":20,"text":1899,"url":20,"identifiers":1900},"M. H. Abraham, P. L. Grellier, D. V. Prior, J. J. Morris and P. J. Taylor, J. Chem. Soc., Perkin Trans. 2, 1990, 521–529.",{},{"id":20,"text":1902,"url":20,"identifiers":1903},"M. H. Abraham, in Computational Approaches in Supramolecular Chemistry, ed. G. Wipff, Kluwer Academic Press, 1994, pp. 63–78.",{"doi":1904},"10.1007\u002F978-94-011-1058-7_4",{"id":20,"text":1906,"url":20,"identifiers":1907},"A. Mezzetti, S. Protti, C. Lapouge and J.-P. Cornard, Phys. Chem. Chem. Phys., 2011, 13, 6858–6864.",{"doi":1908},"10.1039\u002Fc0cp00714e",{"id":20,"text":1910,"url":20,"identifiers":1911},"J. Guharay, B. Sengupta and P. K. Sengupta, Proteins, 2001, 43, 75–81.",{"doi":1912},"10.1002\u002F1097-0134(20010501)43:2\u003C75::AID-PROT1019>3.0.CO;2-7",{"id":20,"text":1914,"url":20,"identifiers":1915},"G. Litwinienko and K. U. Ingold, Acc. Chem. Res., 2007, 40, 222–230.",{"doi":1916},"10.1021\u002Far0682029",{"id":1918,"createTime":1919,"updateTime":1920,"relativeEntities":1921,"slug":1922,"properties":1923,"entityType":192,"verifyStatus":193,"verifyTime":1932,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":1933,"fullTextUrl":20,"authors":1934,"publicationType":245,"publisherRelationship":2000,"citationCount":21,"citationInfo":2047,"publishDate":2050,"publishYear":2048,"citationAnalyzeStatus":19,"lastCitationAnalyze":1920,"indexDatabases":2051,"openAccess":20,"references":2052,"isForceReanalyzing":412},"68fecfbd-1d1b-418c-8064-d3542a482761","2023-12-12T09:10:24.234+00:00","2026-07-21T16:05:28.834+00:00",[],"Laser-trapping-induced-crystallization-ofl-phenylalanine-through-its-high-concentration-domain-formation",{"abstract":1924,"title":1926,"gsPaper":1928,"doi":1930},{"EN":1925},"We present the laser trapping-induced crystallization ofl-phenylalanine through high-concentration domain formation in H2O and D2O solutions which is achieved by focusing a continuous-wave (CW) near-infrared laser beam at the solution surface. Upon laser irradiation into the H2O solution, laser trapping of the liquid-like clusters increases the local concentration, accompanying laser heating, and a single plate-like crystal is eventually prepared at the focal spot. On the other hand, in the D2O solution, a lot of the monohydrate needle-like crystals are observed, not at the focal spot where the concentration is high enough to trigger crystal nucleation, but in the 0.5–1.5 mm range from the focal spot. The dynamics and mechanism of the amazing crystallization behaviour induced by laser trapping are discussed from the viewpoints of the concentration increase due to laser heating depending on solvent, the large high-concentration domain formation by laser trapping of liquid-like clusters, and the orientational disorder of molecules\u002Fclusters at the domain edge.",{"EN":1927},"Laser trapping-induced crystallization ofl-phenylalanine through its high-concentration domain formation",{"VOID":1929},"[\"4693736591592289801\"]",{"VOID":1931},"10.1039\u002Fc3pp50276g","2024-05-05T12:19:06.099+00:00","https:\u002F\u002Flink.springer.com\u002F10.1039\u002Fc3pp50276g",[1935,1952,1965,1987],{"id":1936,"sortIndex":21,"researcher":20,"roles":1937,"affiliations":1938,"properties":1947,"displayName":1949,"givenName":20,"familyName":20},"1f979edd-a640-44fd-86cc-43473d544503",[201],[1939],{"id":1940,"sortIndex":21,"affiliation":1941,"properties":20},"953d2b61-ba87-4bad-87d2-a0e98a036911",{"id":1940,"createTime":20,"updateTime":20,"relativeEntities":1942,"slug":20,"properties":1943,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1946,"statistic":20},[],{"title":1944},{"VI":1945},"Department of Applied Chemistry and Institute of Molecular Science, National Chiao Tung University, Hsinchu, Taiwan",[],{"title":1948,"gsAuthor":1950},{"VI":1949},"Ken-ichi Yuyama",{"VOID":1951},"[\"j90cWD4AAAAJ\"]",{"id":1953,"sortIndex":145,"researcher":20,"roles":1954,"affiliations":1955,"properties":1962,"displayName":1964,"givenName":20,"familyName":20},"4b98ccb7-ebdb-445e-9237-959c890351b3",[201],[1956],{"id":1940,"sortIndex":21,"affiliation":1957,"properties":20},{"id":1940,"createTime":20,"updateTime":20,"relativeEntities":1958,"slug":20,"properties":1959,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1961,"statistic":20},[],{"title":1960},{"VI":1945},[],{"title":1963},{"VI":1964},"Chi-Shiun Wu",{"id":1966,"sortIndex":231,"researcher":20,"roles":1967,"affiliations":1968,"properties":1984,"displayName":1986,"givenName":20,"familyName":20},"de0426ca-d279-42d8-b50a-715b3339b4c1",[201],[1969,1975],{"id":1940,"sortIndex":21,"affiliation":1970,"properties":20},{"id":1940,"createTime":20,"updateTime":20,"relativeEntities":1971,"slug":20,"properties":1972,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1974,"statistic":20},[],{"title":1973},{"VI":1945},[],{"id":1976,"sortIndex":145,"affiliation":1977,"properties":1983},"9885268c-6b5f-4494-9894-952a7e824551",{"id":1976,"createTime":20,"updateTime":20,"relativeEntities":1978,"slug":20,"properties":1979,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1982,"statistic":20},[],{"title":1980},{"VI":1981},"Instrument Technology Research Center, National Applied Research Laboratories, Hsinchu, Taiwan",[],{},{"title":1985},{"VI":1986},"Teruki Sugiyama",{"id":1988,"sortIndex":474,"researcher":20,"roles":1989,"affiliations":1990,"properties":1997,"displayName":1999,"givenName":20,"familyName":20},"d78daa59-b8d9-4fde-accf-5d7e92d45ae6",[201],[1991],{"id":1940,"sortIndex":21,"affiliation":1992,"properties":20},{"id":1940,"createTime":20,"updateTime":20,"relativeEntities":1993,"slug":20,"properties":1994,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":1996,"statistic":20},[],{"title":1995},{"VI":1945},[],{"title":1998},{"VI":1999},"Hiroshi Masuhara",{"url":1933,"publisher":2001,"properties":2042},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2002,"slug":10,"properties":2003,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":2006,"manageAffiliations":2011,"indexDatabases":2022,"url":20,"thumbnailPath":20,"statistic":2037,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":2004,"title":2005},{"VOID":13},{"EN":15},[2007],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":2008,"label":2009,"description":2010,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[2012,2017],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":2013,"slug":20,"properties":2014,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2016,"statistic":20},[],{"title":2015},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":2018,"slug":20,"properties":2019,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2021,"statistic":20},[],{"title":2020},{"EN":43},[37],[2023,2030],{"id":47,"indexDatabase":2024,"url":58,"indexYears":59,"academicFieldIds":2029,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":2025,"label":2026,"description":2027,"key":55,"publicationTags":2028,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":2031,"url":77,"indexYears":20,"academicFieldIds":2036,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":2032,"label":2033,"description":2034,"key":73,"publicationTags":2035,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":2038,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":2039,"totalCitation":121,"totalCitationByYear":2040,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":2041,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"pages":2043,"volume":2045},{"VOID":2044},"254-260",{"VOID":2046},"13",{"total":21,"publishYear":2048,"statisticByYear":2049},2014,{},"2014-02-01",[62,75],[2053,2056,2059,2062,2065,2068,2071,2074,2077,2080,2083,2086,2089,2092,2095,2098,2101,2104,2107,2113,2116,2119,2122,2125,2128,2131,2134],{"id":305,"text":2054,"url":307,"identifiers":2055},"A. Ashkin, Optical trapping and manipulation of neutral particles using lasers, Proc. Natl. Acad. Sci. U. S. A. 1997, 94, 4853.",{"doi":309},{"id":305,"text":2057,"url":307,"identifiers":2058},"C. Hosokawa, H. Yoshikawa and H. Masuhara, Cluster formation of nanoparticles in an optical trap studied by fluorescence correlation spectroscopy, Phys. Rev. E: Stat. Phys., Plasmas, Fluids, Relat. Interdiscip. Top. 2005, 72, 021408.",{"doi":309},{"id":305,"text":2060,"url":307,"identifiers":2061},"Y. Tanaka, H. Yoshikawa, T. Itoh and M. Ishikawa, Laser-induced self-assembly of silver nanoparticles via plasmonic interactions, Opt. Express 2009, 17, 18760.",{"doi":309},{"id":305,"text":2063,"url":307,"identifiers":2064},"W. Singer, T. A. Nieminen, N. R. Heckenberg, H. Rubinsztein-Dunlop, Collecting single molecules with conventional optical tweezers, Phys. Rev. E: Stat. Phys., Plasmas, Fluids, Relat. Interdiscip. Top. 2007, 75, 011916.",{"doi":309},{"id":305,"text":2066,"url":307,"identifiers":2067},"L. Pan, A. Ishikawa and N. Tamai, Detection of optical trapping of CdTe quantum dots by two-photon-induced luminescence, Phys. Rev. B: Condens. Matter 2007, 75, 161305.",{"doi":309},{"id":305,"text":2069,"url":307,"identifiers":2070},"L. Jauffred, A. C. Richardson and L. B. Oddershede, Three-dimensional optical control of individual quantum dots, Nano Lett. 2008, 8, 3376.",{"doi":309},{"id":305,"text":2072,"url":307,"identifiers":2073},"L. Jauffred and L. B. Oddershede, Two-photon quantum dot excitation during optical trapping, Nano Lett. 2010, 10, 1927.",{"doi":309},{"id":305,"text":2075,"url":307,"identifiers":2076},"Y. Tsuboi, T. Shoji and N. Kitamura, Crystallization of lysozyme based on molecular assembling by photon pressure, Jpn. J. Appl. Phys. 2007, 46, L1234.",{"doi":309},{"id":305,"text":2078,"url":307,"identifiers":2079},"T. Shoji, N. Kitamura and Y. Tsuboi, Resonant excitation effect on optical trapping of myoglobin: The important role of a heme cofactor, J. Phys. Chem. C 2013, 117, 10691.",{"doi":309},{"id":305,"text":2081,"url":307,"identifiers":2082},"S. Katsura, K. Hirano, Y. Matsuzawa, K. Yoshikawa and A. Mizuno, Direct laser trapping of single DNA molecules in the globular state, Nucleic Acids Res. 1998, 26, 4943.",{"doi":309},{"id":305,"text":2084,"url":307,"identifiers":2085},"H. Masuhara, T. Sugiyama, T. Rungsimanon, K. Yuyama, A. Miura and J.-R. Tu, Laser-trapping assembling dynamics of molecules and proteins at surface and interface, Pure Appl. Chem. 2011, 83, 869.",{"doi":309},{"id":305,"text":2087,"url":307,"identifiers":2088},"K. Yuyama, T. Sugiyama and H. Masuhara, Millimeter-scale dense liquid droplet formation and crystallization in glycine solution induced by photon pressure, J. Phys. Chem. Lett. 2010, 1, 1321.",{"doi":309},{"id":305,"text":2090,"url":307,"identifiers":2091},"T. Sugiyama, T. Adachi and H. Masuhara, Crystallization of glycine by photon pressure of a focused CW laser beam, Chem. Lett. 2007, 36, 1480.",{"doi":309},{"id":305,"text":2093,"url":307,"identifiers":2094},"T. Rungsimanon, K. Yuyama, T. Sugiyama and H. Masuhara, Crystallization in unsaturated glycine\u002FD2O solution achieved by irradiating a focused continuous wave near infrared laser, Cryst. Growth Des. 2010, 10, 4686.",{"doi":309},{"id":305,"text":2096,"url":307,"identifiers":2097},"K. Yuyama, T. Rungsimanon, T. Sugiyama and H. Masuhara, Selective fabrication of α- and γ-polymorphs of glycine by intense polarized continuous wave laser beams, Cryst. Growth Des. 2012, 12, 2427.",{"doi":309},{"id":305,"text":2099,"url":307,"identifiers":2100},"K. Yuyama, K. Ishiguro, T. Sugiyama and H. Masuhara, Laser trapping dynamics ofl-alanine depending on the laser polarization, Proc. SPIE-Int. Soc. Opt. Eng. 2012, 8458, 84582D.",{"doi":309},{"id":20,"text":2102,"url":20,"identifiers":2103},"K. Yuyama, T. Sugiyama and H. Masuhara, Laser trapping and crystallization dynamics ofl-phenylalanine at solution surface, J. Phys. Chem. Lett. 2013, 4, 2436.",{},{"id":305,"text":2105,"url":307,"identifiers":2106},"Handbook of Chemistry and Physics 1st student edition, ed. R. C. Weast, CRC Press, Inc., 1988, p.C–706.",{"doi":309},{"id":2108,"text":2109,"url":2110,"identifiers":2111},"d8140452-5d80-4fd9-afcb-9a680514ec4a","M. Jelinska-Kazimierczuk and J. Szydlowski, Isotope effect on the solubility of amino acids in water, J. Solution Chem. 1996, 25, 1175.","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002FBF00972645",{"doi":2112},"10.1007\u002FBF00972645",{"id":305,"text":2114,"url":307,"identifiers":2115},"N. C. S. Kee, P. D. Arendt, L. M. Goh, R. B. H. Tan and R. D. Braatz, Nucleation and growth kinetics estimation forl-phenylalanine hydrate and anhydrate crystallization, CrystEngComm 2011, 13, 1197.",{"doi":309},{"id":305,"text":2117,"url":307,"identifiers":2118},"J. Lu, Q. Lin, Z. Li and S. Rohani, Solubility of L-phenylalanine anhydrous and monohydrate forms: Experimental measurements and predictions, J. Chem. Eng. Data 2012, 57, 1492.",{"doi":309},{"id":305,"text":2120,"url":307,"identifiers":2121},"S. Ito, T. Sugiyama, N. Toitani, G. Katayama and H. Miyasaka, Application of fluorescence correlation spectroscopy to the measurement of local temperature in solutions under optical trapping condition, J. Phys. Chem. B 2007, 111, 2365.",{"doi":309},{"id":305,"text":2123,"url":307,"identifiers":2124},"S. Chattopadhyay, D. Erdemir, J. M. B. Evans, J. Ilavsky, H. Amenitsch, C. U. Segre and A. S. Myerson, SAXS study of the nucleation of glycine crystals from a supersaturated solution, Cryst. Growth Des. 2005, 5, 523.",{"doi":309},{"id":20,"text":2126,"url":20,"identifiers":2127},"R. S. Berry, in Large clusters of Atoms and Molecules, ed. T. P. Martin, Kluwer Academic Publ., 1996, p.281.",{},{"id":305,"text":2129,"url":307,"identifiers":2130},"D. W. Oxtoby and Y. C. Shen, Density functional approaches to the dynamics of phase transitions, J. Phys.: Condens. Matter 1996, 8, 9657.",{"doi":309},{"id":305,"text":2132,"url":307,"identifiers":2133},"P. G. Vekilov, Dense liquid precursor for the nucleation of ordered solid phases from solution, Cryst. Growth Des. 2004, 4, 671.",{"doi":309},{"id":20,"text":2135,"url":20,"identifiers":2136},"J. Chen, B. Sarma, J. M. B. Evans and A. S. Myerson, Pharmaceutical crystallization, Cryst. Growth Des. 2011, 11, 887.",{},{"id":2138,"createTime":2139,"updateTime":2140,"relativeEntities":2141,"slug":2142,"properties":2143,"entityType":192,"verifyStatus":193,"verifyTime":2154,"verifyNote":195,"languages":20,"translateLanguages":20,"viewCount":21,"primaryUrl":2155,"fullTextUrl":20,"authors":2156,"publicationType":245,"publisherRelationship":2200,"citationCount":120,"citationInfo":2247,"publishDate":2250,"publishYear":2248,"citationAnalyzeStatus":2251,"lastCitationAnalyze":2140,"indexDatabases":2252,"openAccess":20,"references":20,"isForceReanalyzing":412},"ea38207e-d4b0-4379-8162-3fe7a551b963","2023-12-29T16:15:57.646+00:00","2026-07-20T06:00:11.593+00:00",[],"Light-regulation-of-carotenoid-biosynthesis-in-the-prasinophycean-alga-Mantoniella-squamata",{"abstract":2144,"title":2146,"gsPaper":2148,"references":2150,"doi":2152},{"EN":2145},"We have studied carotenoid biosynthesis in the prasinophycean alga Mantoniella squamata, which contains a great variety of carotenoids belonging to both the a- and the ß-carotene (Car) biosyntheses pathways. This unusual carotenoid composition allowed us to address the problem of how biosynthesis on the a- and the ß-Car pathway is regulated in response to different light regimes. We found that illumination with 4 h of actinic high light (HL, 250 µmol m>-2> s>-1>), and culture growth in permanent light (PL, 60 µmol m>-2> s>-1>), induced the de novo synthesis of violaxanthin (Vx) cycle pigments belonging to the ß-Car pathway. Carotenoid synthesis on the a-Car biosynthesis pathway led to a strong accumulation of lutein (L) and dihydrolutein (DhL). Both the newly synthesised Vx cycle pigments and L\u002FDhL can be regarded as intermediate pools of carotenoids that were converted to light-harvesting pigments in low light (LL) periods following the phases of HL illumination. This transition to the light-harvesting pigments included the conversion of Vx to neoxanthin (Nx) on the ß-Car pathway, and the transformation of L\u002FDhL to prasinoxanthin (Px), the main light-harvesting pigment of M. squamata belonging to the a-carotenoids. Isolation of light-harvesting complexes from L-enriched M. squamata cells showed that both L and the Vx cycle pigments were loosely bound to the LHC apoprotein. This peripheral binding is in agreement with their proposed role as intermediate pigments in the biosynthesis of light-harvesting pigments, and should allow a smooth detachment from the protein in periods of LL when the synthesis of Nx and Px is stimulated. We conclude that carotenoid synthesis proceeds in general in an economical way: in both, the a- and the ß-Car pathway HL induces the formation of photoprotective pigments, which in LL periods following the HL illumination are not degraded, but on the contrary are converted to light-harvesting pigments.",{"EN":2147},"Light regulation of carotenoid biosynthesis in the prasinophycean alga Mantoniella squamata",{"VOID":2149},"[\"17900173333893623355\"]",{"VOID":2151},"B. Demmig-Adams and W. W. Adams III, The role of xanthophyll cycle carotenoids in the protection of photosynthesis, Trends Plant Sci., 1996, 1, 21–26.\nP. Horton, A. V. Ruban and R. G. Walters, Regulation of light harvesting in green plants, Annu. Rev. Plant Physiol. Plant Mol. Biol., 1996, 47, 655–684.\nA. M. Gilmore, Mechanistic aspects of xanthophyll-cycle dependent photoprotection in higher plant chloroplasts and leaves, Physiol. Plant., 1997, 99, 197–209.\nA. Hager and H. Stransky, Das Carotinoidmuster und die Verbreitung des lichtinduzierten Xanthophyllcyclus in verschiedenen Algenklassen. V. Einzelne Vertreter der Cryptophyceae, Euglenophyceae, Bacillariophyceae, Chrysophyceae und Phaeophyceae, Arch. Mikrobiol., 1970, 73, 77–89.\nM. Lohr and C. Wilhelm, Algae displaying the diadinoxanthin cycle also possess the violaxanthin cycle, Proc. Natl. Acad. Sci. USA, 1999, 96, 8784–8789.\nG. Britton, Structure and properties of carotenoids in relation to function, FASEB J., 1995, 9, 1551–1558.\nH. A. Frank and R. J. Cogdell, Carotenoids in photosynthesis, Photochem. Photobiol., 1996, 63, 257–264.\nW. Kühlbrandt, D. N. Wang and Y. Fujiyoshi, Atomic model of plant light-harvesting complex by electron crystallography, Nature, 1994, 367, 614–621.\nB. J. Pogson, K. K. Niyogi, O. Björkman and D. DellaPenna, Altered xanthophyll compositions adversely affect chlorophyll accumulation and nonphotochemical quenching in Arabidopsis mutants, Proc. Natl. Acad. Sci. USA, 1998, 95, 13324–13329.\nC. Wilhelm, The biochemistry and physiology of light-harvesting processes in chlorophyll b- and chlorophyll c-containing algae, Plant Physiol. Biochem., 1990, 28, 293–306.\nC. Wilhelm, S. Kolz, M. Meyer, A. Schmitt, H. Zuber, E. S. Egeland and S. Liaaen-Jensen, Refined carotenoid analysis of the major light harvesting complex of Mantoniella squamata, Photosynthetica, 1997, 33, 161–171.\nS. S. Thayer and O. Björkman, Leaf xanthophyll content and composition in sun and shade determined by HPLC, Photosynth. Res., 1990, 23, 331–343.\nB. Demmig-Adams and W. W. Adams III, Carotenoid composition in sun and shade leaves of plants with different life forms, Plant Cell Environ., 1992, 15, 411–419.\nP. Hugueney, F. Bouvier, A. Badillo, J. Quennemet, A. d’Harlingue and B. Camara, Development and stress regulation of gene expression for plastid and cytosolic isoprenoid pathways in pepper fruits, Plant Physiol., 1996, 111, 619–626.\nF. X. Cunningham, B. Pogson, Z. Sun, K. A. McDonald, D. DellaPenna and E. Gantt, Functional analysis of the ß- and e-lycopene cyclase enzymes of Arabidopsis reveals a mechanism for control of cyclic carotenoid formation, Plant Cell, 1996, 8, 1613–1626.\nZ. Sun, E. Gantt and F. X. Cunningham, Cloning and functional analysis of the ß-carotene hydroxylase of Arabidopsis thaliana, J. Biol. Chem., 1996, 271, 24349–24352.\nF. Bouvier, A. d’Harlingue, P. Hugueney, E. Marin, A. Marion-Poll and B. Camara, Xanthophyll biosynthesis. Cloning, expression, functional reconstitution, and regulation of ß-cyclohexenyl carotenoid epoxidase from pepper (Capsicum annuum), J. Biol. Chem., 1996, 271, 28861–28867.\nE. Marin, L. Nussaume, A. Quesada, M. Gonneau, B. Sotta, P. Hugueney, A. Frey and A. Marion-Poll, Molecular cloning of zeaxanthin epoxidase of Nicotiana plumbaginifolia, a gene involved in abscisic acid biosynthesis and corresponding to the ABA locus of Arabidopsis thaliana, EMBO J., 1996, 15, 2331–2342.\nA. Burbridge, T. Grieve, C. Terry, J. Corlett, A. Thompson and I. Taylor, Structure and expression of a cDNA encoding zeaxanthin epoxidase isolated from a wilt-related tomato (Lycopersicon esculentum Mill.) library, J. Exp. Bot., 1997, 314, 1148–1150.\nF. Bouvier, P. Hugueney, A. d’Harlingue, M. Kuntz and B. Camara, Identification of neoxanthin synthase as a carotenoid cyclase paralog, Eur. J. Biochem., 2000, 267, 6346–6352.\nB. Pogson, K. A. McDonald, M. Truong, G. Britton and D. DellaPenna, Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants, Plant Cell, 1996, 8, 1627–1639.\nE. S. Egeland, W. Eikrem, J. Throndsen, C. Wilhelm, M. Zapata and S. Liaaen-Jensen, Carotenoids from further Prasinophytes, Biochem. Syst. Ecol., 1995, 23, 747–755.\nE. S. Egeland, R. R. L. Guillard and S. Liaaen-Jensen, Additional carotenoid prototype representatives and a general chemosystematic evaluation of carotenoids in Prasinophyceae (Chlorophyta), Phytochemistry, 1997, 44, 1087–1097.\nD. Müller, Über die jahres- und lunarperiodischen Erscheinungen bei einigen Braunalgen, Bot. Mar., 1962, 4, 140–155.\nA. Schmitt, A. Herold, C. Welte, A. Wild and C. Wilhelm, The light-harvesting system of the unicellular alga Mantoniella squamata (Prasinophyceae): evidence for the lack of a photosystem I specific antenna complex, Photochem. Photobiol., 1993, 57, 132–138.\nU. K. Laemmli, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 1970, 227, 680–685.\nR. Goss, K. Böhme and C. Wilhelm, The xanthophyll cycle of Mantoniella squamata converts violaxanthin into antheraxanthin but not to zeaxanthin: consequences for the mechanism of enhanced non-photochemical energy dissipation, Planta, 1998, 205, 613–621.\nR. Goss and C. Wilhelm, in Mantoniella squamata deepoxidized xanthophyll cycle pigments show a tighter pigment protein coupling than the respective epoxidized forms, ed. G. Garab, Photosynthesis: Mechanisms and Effects, Vol. III, Kluwer Academic Publishers, Dordrecht, The Netherlands, 1998,, pp. 2317–2320.\nR. Frommolt, R. Goss and C. Wilhelm, The de-epoxidase and epoxidase reactions of Mantoniella squamata (Prasinophyceae) exhibit different substrate-specific reaction kinetics compared to spinach, Planta, 2001, 213, 446–456.\nB. Depka, P. Jahns and A. Trebst, ß-carotene to zeaxanthin conversion in the rapid turnover of the D1 protein of photosystem II, FEBS Lett., 1998, 424, 267–270.\nL. A. Eichacker, J. Soll, P. Lauterbach, W. Rüdiger, R. B. Klein and J. E. Mullet, In vitro synthesis of chlorophyll a in the dark triggers accumulation of chlorophyll a apoproteins in barley chloroplasts, J. Biol. Chem., 1990, 265, 13566–13571.\nW. Arsalane, B. Rousseau and J. C. Duval, Influence of the pool size of the xanthophyll cycle on the effects of light stress in a diatom: competition between photoprotection and photoinhibition, Photochem. Photobiol., 1994, 60, 237–243.\nB. Demmig-Adams and W. W. Adams III, Photoprotection and other responses of plants to high light stress, Annu. Rev. Plant Physiol. Plant Mol. Biol., 1992, 43, 599–626.\nB. Demmig-Adams, D. L. Moeller, B. A. Logan and W. W. Adams III, Positive correlation between levels of retained zeaxanthin + antheraxanthin and degree of photoinhibition in shade leaves of Schefflera arboricola (Hayata) Merill, Planta, 1998, 205, 367–374.\nB. J. Pogson and R. Rissler, Genetic manipulation of carotenoid biosynthesis and photoprotection, Philos. Trans. R. Soc. London Ser. B, 2000, 355, 1395–1403.\nR. A. Bungard, A. V. Ruban, J. M. Hibberd, M. C. Press, P. Horton and J. D. Scholes, Unusual carotenoid composition and a new type of xanthophyll cycle in plants, Proc. Natl. Acad. Sci. USA, 1999, 96, 1135–1139.\nM. Havaux, Carotenoids as membrane stabilizers in chloroplasts, Trends Plant Sci., 1998, 3, 147–151.\nK. Büch, H. Stransky and A. Hager, FAD is a further essential cofactor of the NAD(P)H and O2-dependent zeaxanthin-epoxidase, FEBS Lett., 1995, 376, 45–48.\nA. D. Parry, M. J. Babiano and R. Horgan, The role of cis-carotenoids in abscisic acid biosynthesis, Planta, 1990, 182, 118–128.\nF. Bouvier, Y. Kell, A. d’Harlingue and B. Camara, Xanthophyll biosynthesis: molecular and functional characterization of carotenoid hydroxylases from pepper fruits (Capsicum anuum L.), Biochim. Biophys. Acta, 1998, 1391, 320–328.\nM. Albrecht, A. Klein, P. Hugueney, G. Sandmann and M. Kuntz, Molecular cloning and functional expression in E. coli of a novel plant enzyme mediating zeta-carotene desaturation, FEBS Lett., 1995, 372, 199–202.",{"VOID":2153},"10.1039\u002Fb204965c","2024-06-26T16:11:43.873+00:00","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1039\u002Fb204965c",[2157,2172,2187],{"id":2158,"sortIndex":21,"researcher":20,"roles":2159,"affiliations":2160,"properties":2169,"displayName":2171,"givenName":20,"familyName":20},"b88a3532-95d0-4c31-af60-f7d11a1d19ca",[201],[2161],{"id":2162,"sortIndex":21,"affiliation":2163,"properties":20},"3a9f1da2-e648-431b-9784-d606730fcf5d",{"id":2162,"createTime":20,"updateTime":20,"relativeEntities":2164,"slug":20,"properties":2165,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2168,"statistic":20},[],{"title":2166},{"VI":2167},"Institut für Botanik, Universität Leipzig, Leipzig, Germany",[],{"title":2170},{"VI":2171},"Karen Böhme",{"id":2173,"sortIndex":145,"researcher":20,"roles":2174,"affiliations":2175,"properties":2182,"displayName":2184,"givenName":20,"familyName":20},"b44f600d-b3f5-46b1-b9e2-98410497cc89",[201],[2176],{"id":2162,"sortIndex":21,"affiliation":2177,"properties":20},{"id":2162,"createTime":20,"updateTime":20,"relativeEntities":2178,"slug":20,"properties":2179,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2181,"statistic":20},[],{"title":2180},{"VI":2167},[],{"title":2183,"gsAuthor":2185},{"VI":2184},"Christian Wilhelm",{"VOID":2186},"[\"MIX6oo0AAAAJ\"]",{"id":2188,"sortIndex":231,"researcher":20,"roles":2189,"affiliations":2190,"properties":2197,"displayName":2199,"givenName":20,"familyName":20},"a81290b3-8fa4-4185-98ee-ed49013e028e",[201],[2191],{"id":2162,"sortIndex":21,"affiliation":2192,"properties":20},{"id":2162,"createTime":20,"updateTime":20,"relativeEntities":2193,"slug":20,"properties":2194,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2196,"statistic":20},[],{"title":2195},{"VI":2167},[],{"title":2198},{"VI":2199},"Reimund Goss",{"url":2155,"publisher":2201,"properties":2242},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2202,"slug":10,"properties":2203,"entityType":18,"verifyStatus":19,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":21,"subjectFields":2206,"manageAffiliations":2211,"indexDatabases":2222,"url":20,"thumbnailPath":20,"statistic":2237,"gsStatistic":20,"type":172,"analyzePriority":20},[],{"issn":2204,"title":2205},{"VOID":13},{"EN":15},[2207],{"id":24,"createTime":20,"updateTime":20,"relativeEntities":2208,"label":2209,"description":2210,"parentId":20,"standard":20,"scholarHubFieldId":20},[],{"EN":27},{},[2212,2217],{"id":31,"createTime":20,"updateTime":20,"relativeEntities":2213,"slug":20,"properties":2214,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2216,"statistic":20},[],{"title":2215},{"EN":35},[37],{"id":39,"createTime":20,"updateTime":20,"relativeEntities":2218,"slug":20,"properties":2219,"entityType":20,"verifyStatus":20,"verifyTime":20,"verifyNote":20,"languages":20,"translateLanguages":20,"viewCount":20,"url":20,"parentIds":2221,"statistic":20},[],{"title":2220},{"EN":43},[37],[2223,2230],{"id":47,"indexDatabase":2224,"url":58,"indexYears":59,"academicFieldIds":2229,"indexDatabaseRanking":62},{"id":49,"createTime":20,"updateTime":20,"relativeEntities":2225,"label":2226,"description":2227,"key":55,"publicationTags":2228,"standard":20},[],{"EN":52,"VI":52},{"EN":52,"VI":54},[57],[61],{"id":64,"indexDatabase":2231,"url":77,"indexYears":20,"academicFieldIds":2236,"indexDatabaseRanking":20},{"id":66,"createTime":20,"updateTime":20,"relativeEntities":2232,"label":2233,"description":2234,"key":73,"publicationTags":2235,"standard":20},[],{"EN":69,"VI":69},{"EN":71,"VI":72},[75,76],[79,80,81],{"impactFactor":21,"impactFactorByYear":2238,"i10Index":95,"i10IndexLast5Year":96,"totalPublication":97,"totalPublicationByYear":2239,"totalCitation":121,"totalCitationByYear":2240,"totalCitationPerPublication":146,"totalCitationPerPublicationByYear":2241,"hindexLast5Year":171,"hindex":171},{"2012":84,"2013":85,"2014":86,"2015":87,"2016":88,"2017":89,"2018":90,"2019":91,"2020":92,"2021":93,"2022":94,"2023":88},{"2002":99,"2003":100,"2004":101,"2005":102,"2006":103,"2007":104,"2008":105,"2009":106,"2010":107,"2011":108,"2012":106,"2013":109,"2014":110,"2015":111,"2016":112,"2017":113,"2018":114,"2019":115,"2020":116,"2021":117,"2022":118,"2023":119,"2024":120},{"2002":123,"2003":124,"2004":125,"2005":126,"2006":127,"2007":128,"2008":129,"2009":130,"2010":131,"2011":132,"2012":133,"2013":134,"2014":135,"2015":136,"2016":137,"2017":138,"2018":139,"2019":140,"2020":141,"2021":142,"2022":143,"2023":144,"2024":145},{"2002":148,"2003":149,"2004":150,"2005":151,"2006":152,"2007":153,"2008":154,"2009":155,"2010":156,"2011":157,"2012":158,"2013":159,"2014":160,"2015":161,"2016":162,"2017":163,"2018":164,"2019":165,"2020":166,"2021":167,"2022":168,"2023":169,"2024":170},{"pages":2243,"volume":2245},{"VOID":2244},"619-628",{"VOID":2246},"1",{"total":120,"publishYear":2248,"statisticByYear":2249},2002,{"2003":145,"2004":231,"2005":145,"2006":145,"2009":145,"2010":474,"2011":231,"2012":231,"2013":145,"2014":145,"2015":231,"2016":231,"2019":145,"2020":145,"2021":945,"2023":145,"2024":145},"2002-06-13","DONE_ANALYZE_CITATION",[62,75]]