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Chem., 256, 3381, 10.1016\u002FS0021-9258(19)69619-5\nBrandon, 1983, l-Glutamic acid: A neurotransmitter candidate for cone photoreceptors in human and rat retinas, 80, 5117\nCooper, 1982, The Biochemical Basis of Neuropharmacology, 249\nDunker, 1969, Observations on molecular weight determinations on polyacrylamide gel, J. biol. Chem., 244, 5074, 10.1016\u002FS0021-9258(18)94310-3\nHawkes, 1982, A dot-immunobinding assay for monoclonal and other antibodies, Analyt. Biochem., 119, 142, 10.1016\u002F0003-2697(82)90677-7\nHeydorn, 1983, Mapping and quantitation of proteins from discrete nuclei and other areas of the rat brain by two-dimensional gel electrophoresis, J. Neurosci., 3, 2597, 10.1523\u002FJNEUROSCI.03-12-02597.1983\nHeydorn, 1984, The effect of desmethylimipramine and reserpine on the concentration of specific proteins in the parietal cortex and the hippocampus of rats as analyzed by two-dimensional gel electrophoresis, J. Pharmac. exp. 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Acta, 309, 83, 10.1016\u002F0005-2744(73)90320-3\nLeung, 1981, Isolation and purification of aspartate aminotransferase isoenzymes from human liver by chromatography and isoelectric focusing, Clin. Chem., 27, 232, 10.1093\u002Fclinchem\u002F27.2.232\nLeung, 1982, Multiple molecular forms of human heart cytoplasmic aspartate aminotransferase, Clin. Sci., 62, 337, 10.1042\u002Fcs0620337\nLin, 1983, Production and characterization of an antibody to cytosolic aspartate aminotransferase and immunolocalization of the enzyme in rat organs, Lab. Invest., 48, 718\nLin, 1983, A comparative study of polyclonal and monoclonal antibodies for immunocytochemical localization of cytosolic aspartate aminotransferase in rat liver, J. Histochem. Cytochem., 31, 920, 10.1177\u002F31.7.6854005\nLin, 1983, Immunocytochemical localization of l-glutamate decarboxylase, gamma-aminobutyric acid transaminase, cysteine sulfinic acid decarboxylase, aspartate aminotransferase and somatostatin in rat retina, Brain Res., 270, 273, 10.1016\u002F0006-8993(83)90601-7\nMagee, 1971, Molecular properties of the multiple aspartate aminotransferase purified from rat brain, Biochemistry, 10, 3397, 10.1021\u002Fbi00794a013\nMarangos, 1975, Isolation and characterization of the nervous system-specific protein 14-3-2 from rat brain, J. biol. Chem., 250, 1884, 10.1016\u002FS0021-9258(19)41777-8\nMarangos, 1978, Neuronal, non-neuronal and hybrid forms of enolase in brain: Structural, immunological and functional comparisons, Brain Res., 150, 117, 10.1016\u002F0006-8993(78)90657-1\nMartinez-Carrion, 1965, Multiple forms of supernatant glutamate-aspartate transaminase from pig heart, Biochem. biophys. Res. Commun., 20, 206, 10.1016\u002F0006-291X(65)90347-5\nMartinez-Rodriguez, 1974, Histochemical localization of glutamic dehydrogenase and aspartate aminotransferase in chicken cerebellum, Brain Res., 69, 31, 10.1016\u002F0006-8993(74)90367-9\nMartinez-Rodriguez, 1982, Histochemical study of aspartate aminotransferase activity in the rat and chicken cerebellum during postnatal development, Cell molec. Biol., 28, 521\nMerril, 1981, Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins, Science, 211, 1437, 10.1126\u002Fscience.6162199\nMerril, 1982, Simplified silver protein detection and image enhancement in polyacrylamide gels, Electrophoresis, 3, 17, 10.1002\u002Felps.1150030104\nNarayan, 1984, Proteins in normal, irradiated and postmortem human brain quantitatvely compared by using two-dimensional gel electrophoresis, Clin. Chem., 30, 1989, 10.1093\u002Fclinchem\u002F30.12.1989\nO'Farrell, 1975, High resolution two-dimensional electrophoresis of proteins, J. biol. Chem., 250, 4007, 10.1016\u002FS0021-9258(19)41496-8\nPalkovits, 1973, Isolated removal of hypothalamic or other brain nuclei of the rat, Brain Res., 59, 449, 10.1016\u002F0006-8993(73)90290-4\nSakakibara, 1980, In vitro synthesis of glutamic oxaloacetic transaminase isozymes of rat liver, Biochem. biophys. Res. Commun., 95, 1781, 10.1016\u002FS0006-291X(80)80105-7\nTowbin, 1979, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications, 76, 4350\nTung, 1971, Effect of charge on the determination of molecular weight of proteins by gel electrophoresis in SDS, Biochem. biophys. Res. Commun., 42, 1117, 10.1016\u002F0006-291X(71)90020-9\nWada, 1964, Comparative studies on glutamic-oxalacetic transaminases from the mitochondrial and soluble fractions of mammalian tissues, Vit. Horm., 22, 411, 10.1016\u002FS0083-6729(08)60346-5\nWilson, 1977, Some improvements in two-dimensional gel electrophoresis of proteins, Analyt. 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Neurosci., 15, 511, 10.1523\u002FJNEUROSCI.15-01-00511.1995\nAlmers, 1990, Trasmitter release from synapses: does a preassembled fusion pore initiate exocytosis?, Neuron, 4, 813, 10.1016\u002F0896-6273(90)90134-2\nAlvarez de Toledo, 1993, Release of secretory products during transient vesicle fusion, Nature, 363, 554, 10.1038\u002F363554a0\nAugustine, 1985, Calcium entry and transmitter release at voltage-clamped nerve terminals of squid, J. Physiol. (Lond), 367, 163, 10.1113\u002Fjphysiol.1985.sp015819\nBenfenati, 1992, Synaptic vesicle-associated Ca2+\u002Fcalmodulin-dependent protein kinase II is a binding protein for synapsin I, Nature, 359, 417, 10.1038\u002F359417a0\nCeccarelli, 1980, Vesicle hypothesis of the release of quanta of acetylcholine, Physiol. Rev., 60, 396, 10.1152\u002Fphysrev.1980.60.2.396\nCeccarelli, 1979, Freeze-fracture studies of frog neuromuscular junctions during intense release of neurotransmitter. II. 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(Lond), 401, 163, 10.1113\u002Fjphysiol.1988.sp017156\nChow, 1992, Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells, Nature, 356, 60, 10.1038\u002F356060a0\nFesce, 1994, Neurotransmitter release: fusion or kiss-and-go?, Trends Cell Biol., 4, 1, 10.1016\u002F0962-8924(94)90025-6\nGansel, 1987, Distinct sites of action of clostridial neurotoxins revealed by double poisoning of mouse motor nerve terminals, Pflügers Arch., 409, 533, 10.1007\u002FBF00583812\nGreengard, 1993, Synaptic vesicle phosphoproteins and regulation of synaptic function, Science, 259, 780, 10.1126\u002Fscience.8430330\nHayashi, 1994, Synaptic vesicle membrane fusion complex: action of clostridial toxins on assembly, EMBO J., 13, 5051, 10.1002\u002Fj.1460-2075.1994.tb06834.x\nHurlbut, 1971, Effects of calcium and magnesium on the frequency of miniature endplate potentials during prolonged tetanization, J. 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Cell Biol., 119, 1395, 10.1083\u002Fjcb.119.6.1395\nMontecucco, 1995, Clostridial neurotoxins, Curr. Top. Microbiol. Immun.\nNeher, 1993, Secretion without full fusion, Nature, 363, 497, 10.1038\u002F363497a0\nNeher, 1994, Mice sans synaptotagmin, Nature, 372, 316, 10.1038\u002F372316a0\nNowak, 1994, All strung out at the synapse, Science, 263, 920, 10.1126\u002Fscience.7906054\nParnas, 1989, Facilitation as a tool to study the entry of calcium and the mechanism of neurotransmitter release, Progr. Neurobiol., 32, 1, 10.1016\u002F0301-0082(89)90026-9\nPopov, 1993, Synaptotagmin: a calcium-sensitive inhibitor of exocytosis?, Cell, 73, 1247, 10.1016\u002F0092-8674(93)90352-Q\nRosahl, 1993, Short-term synaptic plasticity is altered in mice lacking synapsin I, Cell, 75, 861, 10.1016\u002F0092-8674(93)90487-B\nSilva, 1992, Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice, Science, 257, 201, 10.1126\u002Fscience.1378648\nSöllner, 1994, Neurotransmission: harnessing fusion machinery at the synapse, TINS, 17, 344\nSöllner, 1993, A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion, Cell, 75, 409, 10.1016\u002F0092-8674(93)90376-2\nSöllner, 1993, SNAP receptors implicated in vesicle targeting and fusion, Nature, 362, 318, 10.1038\u002F362318a0\nThomas, 1990, Synaptophysin binds to physophilin, a putative synaptic plasma membrane protein, J. 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Pharmac., 32, 505, 10.1016\u002FS1054-3589(08)61021-2\nValtorta, 1994, The presynaptic compartment: signals and targets, 5, 211\nVerhage, 1991, Differential release of amino acids, neuropeptides, and catecholamines from isolated nerve terminals, Neuron, 6, 517, 10.1016\u002F0896-6273(91)90054-4\nWiedenmann, 1985, Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles, Cell, 41, 1017, 10.1016\u002FS0092-8674(85)80082-9\nZhang, 1994, Synaptotagmin I is a high affinity receptor for clathrin AP-2: implications for membrane recycling, Cell, 78, 751, 10.1016\u002FS0092-8674(94)90442-1\nZucker, 1993, Calcium and transmitter release, J. Physiol. 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Neurocytol., 30, 841, 10.1023\u002FA:1019697506757\nCho, 2014, 4-Phenylbutyrate attenuates the ER stress response and cyclic AMP accumulation in DYT1 dystonia cell models, PLoS One, 9, 10.1371\u002Fjournal.pone.0110086\nDel Poeta, 2003, Amount of spontaneous apoptosis detected by Bax\u002FBcl-2 ratio predicts outcome in acute myeloid leukemia (AML), Blood, 101, 2125, 10.1182\u002Fblood-2002-06-1714\nDhaunchak, 2007, A common mechanism of PLP\u002FDM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease, Proc. Natl. Acad. Sci. U.S.A., 104, 17813, 10.1073\u002Fpnas.0704975104\nDuncan, 1989, Myelination in the jimpy mouse in the absence of proteolipid protein, Glia, 2, 148, 10.1002\u002Fglia.440020303\nFarkas-Bargeton, 1972, Abnormal glial maturation in the white matter in Jimpy mice. An optical study, Acta Neuropathol., 21, 272, 10.1007\u002FBF00685135\nFeutz, 2001, An immortalized jimpy oligodendrocyte cell line: defects in cell cycle and cAMP pathway, Glia, 34, 241, 10.1002\u002Fglia.1058\nFlynn, 1991, Peptide-binding specificity of the molecular chaperone Bip, Nature, 353, 726, 10.1038\u002F353726a0\nGarbern, 2007, Pelizaeus-Merzbacher disease: genetic and cellular pathogenesis, Cell. Mol. Life Sci., 64, 50, 10.1007\u002Fs00018-006-6182-8\nGhandour, 2002, Trafficking of PLP\u002FDM20 and cAMP signaling in immortalized jimpy oligodendrocytes, Glia, 40, 300, 10.1002\u002Fglia.10122\nGow, 1994, Many naturally-occurring mutations of myelin proteolipid protein impair its intracellular-transport, J. Neurosci. Res., 37, 574, 10.1002\u002Fjnr.490370504\nGow, 1996, A cellular mechanism governing the severity of Pelizaeus-Merzbacher disease, Nat. 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