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Genet., 11, 183, 10.1146\u002Fannurev.ge.11.120177.001151\nXu, 1980, The isolation and identification of pingyanymycin, Acta Pharmaceutica Sinica, 15, 607",{"EN":442},"Effects of pingyanymycin on chromosomes: A possible structural basis for chromosome aberration",{"VOID":444},"10.1016\u002F0165-1161(88)90248-8","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002F0165116188902488",[447,462,474],{"id":448,"sortIndex":65,"researcher":18,"roles":449,"affiliations":450,"properties":459},"9487cb22-85cf-4d26-9e10-0948cd882a06",[67],[451],{"id":18,"sortIndex":60,"affiliation":452,"properties":18},{"id":453,"createTime":454,"updateTime":454,"relativeEntities":455,"slug":18,"properties":456,"entityType":79,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":60},"9ca58d5b-2e91-4f28-9076-31f296a49049","2024-01-04T23:45:27.631+00:00",[],{"title":457},{"VI":458},"Cell Biology Research Laboratory, Peking Normal University, Beijing P.R. 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Biol., 117, 577, 10.1016\u002F0022-2836(77)90059-6\nGoldberg, 1982, Molecular cloning of the white locus region of Drosophila melanogaster using a large transposable element, EMBO J., 1, 93, 10.1002\u002Fj.1460-2075.1982.tb01130.x\nKelley, 1985, Molecular analysis of X-ray-induced alcohol dehydrogenase (Adh) null mutations in Drosophila melanogaster, Genetics, 109, 365, 10.1093\u002Fgenetics\u002F109.2.365\nLacy, 1986, Molecular analysis of chemically-induced mutations at the RpII215 locus of Drosophila melanogaster, Mutation Res., 162, 47, 10.1016\u002F0027-5107(86)90070-9\nLehrach, 1977, RNA molecular weight determinations by gel electrophoresis under denaturating conditions, a critical reexamination, Biochemistry, 16, 4743, 10.1021\u002Fbi00640a033\nLevis, 1982, Physical map of the white locus of Drosophila melanogaster, 79, 564\nLevis, 1985, Separable cis-acting control elements for the expression of the white gene of Drosophila, EMBO J., 4, 3489, 10.1002\u002Fj.1460-2075.1985.tb04108.x\nManiatis, 1982\nMoschonas, 1981, Structure and expression of a cloned β0 thalassaemic globin gene, Nucleic Acids Res., 9, 4391, 10.1093\u002Fnar\u002F9.17.4391\nNalbantoglu, 1983, Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells, J. 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Biol., 79, 65, 10.1016\u002F0022-2836(73)90270-2\nRigby, 1977, Labelling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase 1, J. Mol. Biol., 113, 237, 10.1016\u002F0022-2836(77)90052-3\nSinger, 1976, All oxygens in nucleic acids react with carcinogenic ethylating agents, Nature (London), 264, 333, 10.1038\u002F264333a0\nTwigg, 1980, Trans-complementable copy-number mutants of plasmid Co1E1, Nature (London), 283, 216, 10.1038\u002F283216a0\nVogel, 1979, The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems, I. Recessive lethal mutations and translocations in Drosophila, Mutation Res., 62, 51, 10.1016\u002F0027-5107(79)90223-9\nVogel, 1982, The relation between reaction kinetics and mutagenic action of monofunctional alkylating agents in higher eukaryotic systems: Interspecies comparisons, Vol. 7, 295\nVogel, 1986, Alkylation-induced mutagenesis in higher eukaryotic systems: significance of DNA modifications and DNA repair with regard to genetic endpoints, 219\nZacher, 1982, Regulation of white locus expression: the structure of mutant alleles at the white locus of Drosophila melanogaster, Cell, 30, 529, 10.1016\u002F0092-8674(82)90250-1",{"EN":519},"The nature of N-ethyl-N-nitrosourea-induced mutations at the white locus of Drosophila melanogaster",{"VOID":521},"10.1016\u002F0165-1161(88)90231-2","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002F0165116188902312",[524,539,561],{"id":525,"sortIndex":65,"researcher":18,"roles":526,"affiliations":527,"properties":536},"46ca851b-62df-425c-acd0-9990017f2cec",[67],[528],{"id":18,"sortIndex":60,"affiliation":529,"properties":18},{"id":530,"createTime":531,"updateTime":531,"relativeEntities":532,"slug":18,"properties":533,"entityType":79,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":60},"2296ebdd-15f8-449b-b299-c01f7716691d","2024-01-01T10:20:49.456+00:00",[],{"title":534},{"VI":535},"Department of Radiation Genetics and Chemical Mutagenesis, State University of Leiden, Wassenaarseweg 72, Leiden, The Netherlands",{"title":537},{"VI":538},"Ekkehart W. 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Biochem., 110, 1, 10.1016\u002F0003-2697(81)90103-2\nGould, 1980, Mammary gland cell-mediated mutagenesis of mammalian cells by organ-specific carcinogens, Cancer Res., 40, 1836\nGuy, 1981, Tumor promoter inhibition of intercellular communication between cultured mammalian cells, Carcinogenesis, 2, 223, 10.1093\u002Fcarcin\u002F2.3.223\nHass, 1982, Cell-mediated mutagenicity in Chinese hamster V79 cells of dibenzopyrenes and their bay-region fluorine-substituted derivatives, Cancer Res., 42, 1646\nHsu, 1978, Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbon, 75, 2003\nHuberman, 1974, Cell-mediated mutagenesis of mammalian cells with chemical carcinogens, Int. J. Cancer, 13, 326, 10.1002\u002Fijc.2910130308\nHuberman, 1976, Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons, 73, 188\nHuberman, 1979, Mutagenicity and tumor-initiating activity of fluorinated derivations of 7,12-dimethylbenz[a]anthracene, Cancer Res., 39, 411\nJenssen, 1979, Mutagenicity testing on Chinese hamster V79 cells treated in the in vitro liver perfusion system; Comparative investigation of different in vitro metabolizing systems with dimethylnitrosamine and benzo[a]pyrene, Chem.-Biol. Interact., 27, 27, 10.1016\u002F0009-2797(79)90147-9\nJones, 1980, A sensitive hepatocyte-mediated assay for the metabolism of nitrosamines to mutagens for mammalian cells, Cancer Res., 40, 406\nJones, 1981, The relationship between the carcinogenicity and mutagenicity of nitrosamines in a hepatocyte-mediated mutagenicity assay, Carcinogenesis, 2, 1075, 10.1093\u002Fcarcin\u002F2.10.1075\nLangenbach, 1978, Liver cell-mediated mutagenesis of mammalian cells by liver carcinogens, 75, 2864\nLangenbach, 1978, Cell specificity in metabolic activation of the carcinogens aflatoxin B1 and benzo[a]pyrene to mutagens for mammalian cells, Nature (London), 276, 277, 10.1038\u002F276277a0\nLangenbach, 1981, Rat bladder cell-mediated mutagenesis of Chinese hamster V79 cells and metabolism of benzo[a]pyrene, J. Natl. Cancer Inst., 66, 913\nMichalopoulos, 1981, Mutagenesis induced by procarcinogens at the hypoxanthineguanine phosphoribosyl transfrase locus of human fibroblassts cocultured with rat hepatocytes, Cancer Res., 41, 1873\nMurray, 1979, Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells, Biochem, Biophys. Res. Commun., 91, 395, 10.1016\u002F0006-291X(79)91535-3\nNewbold, 1981, Inhibition of metabolic cooperation between mammalian cells in culture by tumor promoters, Carcinogenesis, 2, 243, 10.1093\u002Fcarcin\u002F2.3.243\nRaveh, 1982, Cell-mediated mutagenesis and tumor-initiating activity of the ubiquitous polycyclic hydrocarbon, cyclopenta[c,d]pyrene, Carcinogenesis, 7, 726\nYotti, 1979, Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter, Science, 206, 1089, 10.1126\u002Fscience.493994",{"EN":609},"A microtiter plate assay for the selection of 6-thioguanine-resistant mutants in Chinese hamster V79 cells in the presence of phorbol-12-myristate-13-acetate",{"VOID":611},"10.1016\u002F0165-1161(83)90004-3","2025-01-13T23:44:46.204+00:00","Author affiliation is blank","https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002F0165116183900043",[616,623],{"id":617,"sortIndex":60,"researcher":18,"roles":618,"affiliations":619,"properties":620},"a56f59a0-3014-4a64-920c-ed09b145bd2c",[67],[],{"title":621},{"VI":622},"Dina Raveh",{"id":624,"sortIndex":71,"researcher":18,"roles":625,"affiliations":626,"properties":627},"0ff7302d-db16-4fcb-b0db-c3fd0fe95ffd",[67],[],{"title":628},{"VI":629},"Eliezer Huberman",{"url":614,"publisher":631,"properties":645},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":632,"slug":10,"properties":633,"entityType":16,"verifyStatus":17,"verifyTime":18,"verifyNote":18,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":19,"subjectFields":636,"manageAffiliations":637,"indexDatabases":638,"url":18,"thumbnailPath":18,"statistic":18,"gsStatistic":18,"type":18,"analyzePriority":18},[],{"issn":634,"title":635},{"VOID":13},{"EN":15},[],[],[639],{"id":24,"indexDatabase":640,"url":37,"indexYears":38,"academicFieldIds":18,"indexDatabaseRanking":39},{"id":26,"createTime":27,"updateTime":28,"relativeEntities":641,"label":642,"description":643,"key":34,"publicationTags":644,"standard":18},[],{"EN":31,"VI":31},{"EN":31,"VI":33},[36],{"volume":646,"pages":647},{"VOID":286},{"VOID":648},"499-506","1983-10-01",{"id":651,"createTime":652,"updateTime":653,"relativeEntities":654,"slug":655,"properties":656,"entityType":57,"verifyStatus":58,"verifyTime":653,"verifyNote":59,"syncStatus":17,"languages":18,"translateLanguages":18,"viewCount":60,"primaryUrl":663,"fullTextUrl":18,"authors":664,"publicationType":188,"publisherRelationship":712,"citationCount":18,"citationInfo":18,"publishDate":732,"publishYear":354,"citationAnalyzeStatus":17,"lastCitationAnalyze":18,"indexDatabases":18,"openAccess":18,"references":18,"isForceReanalyzing":211},"4e87ec87-71e3-4fd3-9929-7c26812d9943","2024-01-12T17:27:39.590+00:00","2025-01-10T23:34:19.996+00:00",[],"EMS-induced-dominant-lethal-dose-response-curve-in-DBA-1J-male-mice",{"references":657,"title":659,"doi":661},{"VOID":658},"Bateman, 1958, Partition of dominant lethals in the mouse between unimplanted eggs and deciduomata, Heredity, 12, 467, 10.1038\u002Fhdy.1958.47\nBateman, 1958, Testing chemicals for mutagenicity in a mammal, Nature (Lond.), 210, 205, 10.1038\u002F210205a0\nBautz, 1960, On the mutagenic effect of alkylating agents, 46, 1585\nCacheiro, 1974, Translocations, the predominant cause of total sterility in sons of mice treated with mutagens, Genetics, 76, 73, 10.1093\u002Fgenetics\u002F76.1.73\nCattanach, 1968, Ethyl methanesulfonate-induced chromosome breakage in the mouse, Mutation Res., 6, 297, 10.1016\u002F0027-5107(68)90045-6\nEhling, 1971, Comparison of radiation- and chemically-induced dominant lethal mutations in male mice, Mutation Res., 11, 35, 10.1016\u002F0027-5107(71)90030-3\nEhling, 1965, Induction of dominant lethal mutations by alkylating agents in male mice, Mutation Res., 5, 417, 10.1016\u002F0027-5107(68)90011-0\nEhling, 1968, Differential mutagenic action of n- and isopropyl methanesulfonate in mice, 1, 103\nFox, 1969, Sensitivity of the newly synthesized and template DNA of lymphoma cells to damage by methyl methanesulfonate, and the nature of associated “repair” process, Mutation Res., 8, 629, 10.1016\u002F0027-5107(69)90081-5\nFreese, 1961, Transitions and transversions induced by depurinating agents, 47, 540\nGeneroso, 1969, Strain and sex variation in the sensitivity of mice to dominant-lethal induction with ethyl methanesulfonate, Mutation Res., 8, 589, 10.1016\u002F0027-5107(69)90077-3\nGeneroso, 1971, Chemically induced dominant-lethal mutations and cell killing in mouse oocytes in the advanced stages of follicular development, Mutation Res., 11, 411\nGeneroso, 1974, Effects of dose on the induction of dominant-lethal mutations and heritable translocations with ethyl methanesulfonate in male mice, Genetics, 77, 741, 10.1093\u002Fgenetics\u002F77.4.741\nLawley, 1963, The action of alkylating agents on deoxyribonucleic acid in relation to biological effects of the alkylating agents, Cell Res. (Suppl.), 9, 512, 10.1016\u002F0014-4827(63)90291-X\nLeonard, 1972, Observations of dividing spermatocytes for chromosome aberrations induced in mouse spermatogonia by chemical mutagens, Mutation Res., 16, 297, 10.1016\u002F0027-5107(72)90160-1\nMosteller, 1961, Tables of the Freeman-Tukey transformations for the binomial and Poisson distributions, Biometrika, 48, 433, 10.1093\u002Fbiomet\u002F48.3-4.433\nMoutschen, 1969, Mutagenesis with methyl methanesulfonate in mouse, Mutation Res., 8, 581, 10.1016\u002F0027-5107(69)90076-1\nOakberg, 1960, Irradiation damage to animals and its effect on their reproductive capacity, J. Dairy Sci. (Suppl.), 43, 54\nOakberg, 1960, X-ray sensitivity of primary spermatocytes of the mouse, Intern. J. Radiation Biol., 2, 196, 10.1080\u002F09553006014550211\nPartington, 1963, The induction of dominant-lethal mutations in rats by alkanesulfonic esters, Genet. Res., 4, 333, 10.1017\u002FS0016672300003736\nRohrborn, 1971, Induced chromosome aberrations in early embryo-genesis of mice, Human Genetik, 11, 316, 10.1007\u002FBF00278659\nSoares, 1972, Estimating the frequency of induced dominant lethals in mice by uterine dissection after weaning progeny, Mutation Res., 16, 425, 10.1016\u002F0027-5107(72)90213-8\nSoares, 1972, Estimating the frequency of dominant lethal mutations, II. The evaluation of a new method, J. 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Egypt. Natl. Cancer. Inst., 5, 443\nAltschull, 1958\nBaggott, 1990, Effect of Miso (Japanese soybean paste) and NaCl on DMBA-induced rat mammary tumors, Nutr. Cancer, 14, 103, 10.1080\u002F01635589009514083\nBartsch, 1988, Inhibitors of endogenous nitrosation. Mechanisms and implications in human cancer prevention, Mutation Res., 202, 307, 10.1016\u002F0027-5107(88)90194-7\nButler, 1976, 89\nCarleton, 1980\nDe Hondt, 1984, Chromosomal and biochemical studies on the effect of Kat extract on laboratory rats, Environ. Mutation, 6, 851, 10.1002\u002Fem.2860060611\nDruckey, 1964, Selective induction of bladder cancer in rats by dibutylamine and N-butyl-N-Butanol (4)-nitrosamine, Z. Krebsforsch., 66, 280\nEl-Aaser, 1986, Effect of soybean feeding on experimental carcinogenesis. I. Hepatocarcinogenesis by p-dimethylamino azobenzene (DAB) on rats fed soybean: Histopathological and histochemical studies, J. Egypt. Natl. Cancer Inst., 2, 443\nFarber, 1973, Hyperplastic liver nodules, Methods Cancer Res., 7, 345\nFarsund, 1978, Cell kinetics of mouse urinary bladder epithelium. VI. Changes in proliferation and nuclear DNA content after repeated doses of dibutylnitrosamine, Virchow Arch. (Cell Pathol.), 27, 119, 10.1007\u002FBF02888988\nHashimoto, 1972, Induction of urinary bladder tumors in ACI\u002FN rats by butyl(3-carboxypropyl)nitrosamine, a major urinary metabolite of butyl(4-hydroxybutyl)nitrosamine, GANN, 63, 637\nHayatsu, 1988, Dietary inhibitors of mutagenesis and carcinogenesis, Mutation Res., 202, 429, 10.1016\u002F0027-5107(88)90204-7\nHeath, 1962, The decomposition and toxicity of dialkylnitrosamines in rats, Biochem. J., 64, 476\nKennedy, 1993, Effects of various preparations of dietary protease inhibitors on oral carcinogenesis in Hamsters induced by DMBA, Nutr. Cancer, 19, 191, 10.1080\u002F01635589309514249\nKihlman, 1966\nKilian, 1977, 243\nKunze, 1971, Autoradiographische Untersuchungen uber dem RNS-stoffwechsel wahrend der Entwicklung von Dibutylnitrosamin induzierten Karnblasen, Z. Krebsforsch., 76, 246, 10.1007\u002FBF00304028\nKurechi, 1981, Inhibition of N-nitrosamine formation by soy products, J Food Cosmet. Toxicol., 19, 425, 10.1016\u002F0015-6264(81)90445-4\nMagee, 1976, N-Nitroso compounds and related carcinogens, 491\nMessadi, 1986, Inhibition or oral carcinogenesis by a protease inhibitor, JNCI, 76, 447\nMelmed, 1976, Hypertrophy and hyperplasia of the neonatal rat exocrine pancreas induced by oral administered soybean Trypsin inhibitor, Biochim. Biophys. Acta, 421, 280, 10.1016\u002F0304-4165(76)90294-4\nMirvish, 1983, The etiology of gastric cancer: Intragastric nitrosamide formation and other theories, JNCI, 71, 631\nNegishi, 1982, 649\nOhshima, 1981, Quantitative estimation of endogenous nitrosation in human by monitoring N-nitrosoproline excreted in the urine, Cancer Res., 41, 3658\nPreussmann, 1982, 217\nRumruen, 1984, Metabolic activation capabilities of S9 and hepatocytes from uninduced rats to convert carcinogenic N-nitrosamines to mutagens, Mutation Res., 140, 147, 10.1016\u002F0165-7992(84)90060-5\nSinger, 1979, N-Nitrosoalkylating agents. Formation and persistence of alkyl derivatives in mammalian nucleic acids and contributing factors in carcinogenesis, JNCI, 62, 1329\nStevenson, 1971, Chromosomal studies in patients taking phenylbutazone, Ann. Rheum. Dis., 30, 487, 10.1136\u002Fard.30.5.487\nTannenbaum, 1976, The effect of nitrate intake on nitrite formation in human saliva, Food Cosmet. Toxicol., 14, 549, 10.1016\u002FS0015-6264(76)80006-5\nTricker, 1991, Carcinogenic N-nitrosamines in the deit: Occurrence, formation, mechanisms and carcinogenic potential, Mutation Res., 259, 277, 10.1016\u002F0165-1218(91)90123-4\nTroll, 1976, 41\nTroll, 1971, Tumorigenesis in mouse skin: Inhibition by synthetic inhibitors of proteases, Science, 169, 1211, 10.1126\u002Fscience.169.3951.1211\nTroll, 1979, 20, 265\nWood, 1970, The carcinogenic activity of dibutylnitrosamine in IFXC 57 mice, Eur. J. 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Test validation and interpretation, Mutation Res., 72, 447, 10.1016\u002F0027-5107(80)90118-9\nAmacher, 1979, Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells I. Application to genetic toxicological testing, Mutation Res., 64, 391, 10.1016\u002F0165-1161(79)90109-2\nAmacher, 1980, Promutagen activation by rodent-liver postmitochondrial fractions in the L5178Y\u002FTK cell mutation assay, Mutation Res., 74, 485, 10.1016\u002F0165-1161(80)90179-X\nAmacher, 1980, The detection of carcinogens from several chemical classes as mutagens in a modified L5178Y TK mutation assay, Environ. Mutagen., 2, 254\nAmes, 1973, Carcinogens are mutagens: A simple test combining liver homogenaies for activation and bacteria for detection, 80, 2281\nClive, 1972, A mutational assay system using the thymidine kinase locus in mouse lymphoma cells, Mutation Res., 16, 77, 10.1016\u002F0027-5107(72)90066-8\nClive, 1979, Validation and characterization of the L5178Y\u002FTK+\u002F− mouse lymphoma mutagen assay system, Mutation Res., 59, 61, 10.1016\u002F0027-5107(79)90195-7\nClive, 1975, Laboratory procedure for assessing specific locus mutations at the TK locuscultured L5178Y mouse lymphoma cells, Mutation Res., 31, 17, 10.1016\u002F0165-1161(75)90059-X\nCourtenay, 1972, Loss of resistance to methotrexate in L5187Y mouse leukemia grown in vitro, J. Natl. Cancer Inst., 49, 45\nGutmann, 1977, N-Hydroxylation of arylamides by the rat and guinea pig, Evidence for substrate specificity and participation of cytochrome P1-450, Biochim. Biophys. 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