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or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":576},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[580],{"id":581,"createTime":24,"updateTime":24,"relativeEntities":582,"slug":24,"properties":583,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":593,"parentIds":594,"statistic":24},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":584,"address":587,"country":590,"abbreviation":591},{"EN":585,"VI":586},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":588,"VI":589},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":104},{"VOID":592},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":25,"impactFactorByYear":598,"i10Index":25,"i10IndexLast5Year":25,"totalPublication":600,"totalPublicationByYear":601,"totalCitation":606,"totalCitationByYear":607,"totalCitationPerPublication":194,"totalCitationPerPublicationByYear":609,"hindexLast5Year":131,"hindex":131},{"2022":599,"2023":197,"2024":192},0.01,1556,{"2020":133,"2021":602,"2022":603,"2023":604,"2024":605,"2025":208},57,306,801,358,161,{"2021":232,"2022":366,"2023":608},99,{"2021":610,"2022":404,"2023":190},0.23,{"impactFactor":24,"impactFactorByYear":24,"i10Index":209,"i10IndexLast5Year":209,"totalPublication":612,"totalPublicationByYear":613,"totalCitation":612,"totalCitationByYear":614,"totalCitationPerPublication":126,"totalCitationPerPublicationByYear":617,"hindexLast5Year":135,"hindex":135},476,{"0":291,"2019":209,"2021":225,"2022":545,"2023":537,"2024":443,"2025":135,"2026":134},{"2021":128,"2022":209,"2023":247,"2024":615,"2025":446,"2026":616},136,83,{"2021":191,"2022":599,"2023":618,"2024":213,"2025":619,"2026":620},0.62,25.43,13.83,{"id":622,"createTime":623,"updateTime":468,"relativeEntities":624,"slug":625,"properties":626,"entityType":22,"verifyStatus":114,"verifyTime":24,"verifyNote":24,"languages":638,"translateLanguages":24,"viewCount":219,"subjectFields":639,"manageAffiliations":640,"indexDatabases":641,"url":642,"thumbnailPath":643,"statistic":644,"gsStatistic":680,"type":141,"analyzePriority":24},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":627,"issn":628,"title":630,"introduce":633,"gsId":636},{"VOID":104},{"VOID":629},"25252445",{"EN":631,"VI":632},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":634,"VI":635},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. Since then, the journal has grown in quality, size and scope and now comprises a dozen of serials spanning academic research. 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Although, the main text structure may vary based on the review subtopics, the articles should be formatted according to suitable Templates as research articles.\"},{\"attributes\":{\"align\":\"justify\"},\"insert\":\"\\n\"},{\"insert\":\"\\n\"}]}","{\"ops\":[{\"insert\":\"Tạp chí Khoa học Trường ĐHSP Hà Nội 2 nhằm mục đích cung cấp một nền tảng liên ngành của sự phổ biến những tiến bộ của khoa học và công nghệ. Tạp chí xuất bản các bài báo gốc có giá trị khoa học hoặc công nghệ trong tất cả các lĩnh vực khoa học tự nhiên, xã hội hoặc giáo dục.\\n\"},{\"attributes\":{\"bold\":true},\"insert\":\"Chuyên san Khoa học tự nhiên và công nghệ:\"},{\"insert\":\" Là các bài báo mô tả những phát hiện có giá trị trong vật lý, toán học, hóa học, sinh học; giải quyết các vấn đề kỹ thuật hoặc công nghệ.\"},{\"attributes\":{\"list\":\"bullet\"},\"insert\":\"\\n\"},{\"attributes\":{\"bold\":true},\"insert\":\"Chuyên san Khoa học Xã hội và Nhân văn:\"},{\"insert\":\" là các bài báo xuất bản chất lượng cao trong các lĩnh vực khác nhau của khoa học xã hội và nghiên cứu phát triển con người.\"},{\"attributes\":{\"list\":\"bullet\"},\"insert\":\"\\n\"},{\"attributes\":{\"bold\":true},\"insert\":\"Chuyên san Khoa học giáo dục:\"},{\"insert\":\" là các bài báo xuất bản trong lĩnh vực khoa học giáo dục và các ứng dụng của tiến bộ vào giáo dục để cải thiện và nâng cao giáo dục khoa học ở tất cả các cấp.\"},{\"attributes\":{\"list\":\"bullet\"},\"insert\":\"\\n\"},{\"insert\":\"Tạp chí trường ĐHSP Hà Nội 2 xuất bản được phản biện kín, xét duyệt bởi ít nhất 02 chuyên gia, và được đánh giá, chọn lựa từ ban biên tập và Tổng biên tập.\\n\"},{\"attributes\":{\"bold\":true},\"insert\":\"Các loại bài báo\"},{\"insert\":\":\\nBài báo nghiên cứu:\"},{\"attributes\":{\"list\":\"ordered\"},\"insert\":\"\\n\"},{\"insert\":\"Báo cáo học thuật về nghiên cứu ban đầu chưa từng được xuất bản ở bất kỳ nơi nào, hay bằng bất kỳ ngôn ngữ nào khác. Bản thảo thích hợp, nên chứa các phần sau theo thứ tự: Tiêu đề, Tác giả, Liên kết tác giả, Địa chỉ email của tác giả tương ứng, Tóm tắt, Từ khóa, Danh pháp (nếu có), Giới thiệu, Thử nghiệm, Lý thuyết, Kết quả và thảo luận, Kết luận, Xung đột quan tâm, Lời cảm ơn (nếu có), Tài liệu tham khảo, Phụ lục (nếu có). Bản xuất bản trước phải được định dạng theo Mẫu (phiên bản MS-Word).\\n2. Bài báo tổng quan:\\nNgoài các bài phê bình được mời, các bài phê bình tài liệu, bài phê bình có hệ thống và bài phê bình sẽ được chấp nhận để xem xét. Bản thảo cần được soạn thảo và sắp xếp theo trình tự yêu cầu: Tên sách, Tên tác giả, Liên kết, Địa chỉ email, Tóm tắt, Từ khóa, Nội dung chính, Kết luận, Xung đột lợi ích, Lời cảm ơn (nếu có), Tài liệu tham khảo. Mặc dù, cấu trúc văn bản chính có thể thay đổi dựa trên các chủ đề phụ của bài đánh giá, các bài báo nên được định dạng theo các Mẫu phù hợp như các bài báo nghiên cứu.\\n\"}]}",{"VOID":812},"YPoBvsIAAAAJ",[],[],[],"https:\u002F\u002Fsj.hpu2.edu.vn\u002Findex.php\u002Fjournal","\u002Fapi\u002Fpublic\u002Ffile\u002Fpublisher\u002F954132b5-ca74-461c-b819-45ad6e49a404\u002F2790ef1d0a7d7a40a504c2fc1647f670.jpg",{"impactFactor":25,"impactFactorByYear":819,"i10Index":25,"i10IndexLast5Year":25,"totalPublication":415,"totalPublicationByYear":821,"totalCitation":220,"totalCitationByYear":822,"totalCitationPerPublication":610,"totalCitationPerPublicationByYear":823,"hindexLast5Year":209,"hindex":209},{"2024":820},0.17,{"2022":222,"2023":364,"2024":228},{"2022":443,"2023":212,"2024":209},{"2022":255,"2023":310,"2024":251},{"impactFactor":24,"impactFactorByYear":24,"i10Index":131,"i10IndexLast5Year":131,"totalPublication":416,"totalPublicationByYear":825,"totalCitation":240,"totalCitationByYear":826,"totalCitationPerPublication":827,"totalCitationPerPublicationByYear":828,"hindexLast5Year":132,"hindex":132},{"0":209,"2022":220,"2023":222,"2024":155,"2025":231},{"2023":132,"2024":222,"2025":287,"2026":364},1.22,{"2023":199,"2024":426,"2025":829},4.56,{"id":831,"createTime":832,"updateTime":833,"relativeEntities":834,"slug":835,"properties":836,"entityType":22,"verifyStatus":114,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":155,"subjectFields":848,"manageAffiliations":849,"indexDatabases":857,"url":897,"thumbnailPath":24,"statistic":898,"gsStatistic":930,"type":141,"analyzePriority":24},"21ccdb34-414d-420f-8a60-a592a2fa848e","2023-05-29T10:42:53.358+00:00","2026-08-27T01:57:29.560+00:00",[],"Vietnam-Journal-of-Earth-Sciences",{"country":837,"eissn":838,"issn":840,"title":842,"introduce":844,"gsId":846},{"VOID":104},{"VOID":839},"26159783",{"VOID":841},"08667187",{"EN":843},"Vietnam Journal of Earth Sciences",{"EN":845},"Science of the Earth, formerly Vietnam Journal of Earth Sciences, is a peer-reviewed journal to publish high-quality articles on the entire range of earth sciences and the environment, focused on the Asia Pacific region and their correlations and connections to the globe. The journal publishes fundamental and applied research in earth sciences and the environment, including geology, geophysics, geography, soil science, hydrology, meteorology, oceanography, petroleum, geohazards, environmental sciences, environmental engineering, sustainable development, geoinformatics, geodesy, GIS, and remote sensing.",{"VOID":847},"5htfr3YAAAAJ",[],[850],{"id":159,"createTime":24,"updateTime":24,"relativeEntities":851,"slug":24,"properties":852,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":168,"parentIds":856,"statistic":24},[],{"title":853,"country":854,"abbreviation":855},{"EN":163,"VI":164},{"VOID":104},{"VOID":167},[],[858,870,881],{"id":859,"indexDatabase":860,"url":865,"indexYears":866,"academicFieldIds":867,"indexDatabaseRanking":869},"6ace2085-a177-4a27-b309-8813b832111e",{"id":58,"createTime":24,"updateTime":24,"relativeEntities":861,"label":862,"description":863,"key":64,"publicationTags":864,"standard":24},[],{"EN":61,"VI":61},{"EN":61,"VI":63},[66],"https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21101039869","2018-2024",[868],"1689391c-5702-4349-aaa7-d720ee4321fc","NONE",{"id":871,"indexDatabase":872,"url":877,"indexYears":878,"academicFieldIds":879,"indexDatabaseRanking":24},"dadb15a8-ee22-41c2-a287-49e969d9a998",{"id":174,"createTime":24,"updateTime":24,"relativeEntities":873,"label":874,"description":875,"key":180,"publicationTags":876,"standard":24},[],{"EN":177,"VI":177},{"EN":179,"VI":179},[182],"https:\u002F\u002Fasean-cites.org\u002Fjournal_info?jid=10629","2016-2022",[880],"e04f14cf-280b-4aa8-b711-b77ddd79cbaf",{"id":882,"indexDatabase":883,"url":894,"indexYears":24,"academicFieldIds":895,"indexDatabaseRanking":24},"06f278ee-37b9-41eb-a9b0-3d2d77fa502b",{"id":884,"createTime":24,"updateTime":24,"relativeEntities":885,"label":886,"description":888,"key":891,"publicationTags":892,"standard":24},"88bab0f7-443b-476c-a72a-7fa5222da393",[],{"EN":887,"VI":887},"ISI\u002FESCI  - 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The prototype recombinant in this series, pSV2-cat, consisted of the beta-lactamase gene and origin of replication from pBR322 coupled to a simian virus 40 (SV40) early transcription region into which CAT coding sequences were inserted. Readily measured levels of CAT accumulated within 48 h after the introduction of pSV2-cat DNA into African green monkey kidney CV-1 cells. Because endogenous CAT activity is not present in CV-1 or other mammalian cells, and because rapid, sensitive assays for CAT activity are available, these recombinants provided a uniquely convenient system for monitoring the expression of foreign DNAs in tissue culture cells. To demonstrate the usefulness of this system, we constructed derivatives of pSV2-cat from which part or all of the SV40 promoter region was removed. Deletion of one copy of the 72-base-pair repeat sequence in the SV40 promoter caused no significant decrease in CAT synthesis in monkey kidney CV-1 cells; however, an additional deletion of 50 base pairs from the second copy of the repeats reduced CAT synthesis to 11% of its level in the wild type. We also constructed a recombinant, pSV0-cat, in which the entire SV40 promoter region was removed and a unique HindIII site was substituted for the insertion of other promoter sequences.\u003C\u002Fjats:p>","\u003Cjats:p>Chúng tôi đã xây dựng một loạt các hệ gen tái tổ hợp, nhằm điều khiển sự biểu hiện của enzyme chloramphenicol acetyltransferase (CAT) trong các tế bào động vật có vú. Hệ gen tái tổ hợp nguyên mẫu trong loạt này, pSV2-cat, bao gồm gen beta-lactamase và khởi đầu cho sự tái bản từ pBR322 nối với vùng phiên mã sớm của virus khỉ 40 (SV40) mà vào đó các trình tự mã hóa cho CAT đã được chèn vào. Mức độ CAT tích lũy có thể đo lường dễ dàng trong vòng 48 giờ sau khi DNA pSV2-cat được đưa vào tế bào thận khỉ xanh châu Phi CV-1. Do không có hoạt tính CAT nội sinh trong CV-1 hoặc các tế bào động vật có vú khác, và do có sẵn các xét nghiệm nhanh, nhạy cảm cho hoạt tính CAT, nên các hệ gen tái tổ hợp này cung cấp một hệ thống độc đáo thuận tiện để giám sát sự biểu hiện của DNA ngoại lai trong các tế bào nuôi cấy mô. Để chứng minh tính hữu dụng của hệ thống này, chúng tôi đã xây dựng các dẫn xuất của pSV2-cat mà từ đó một phần hoặc toàn bộ vùng promoter SV40 đã bị loại bỏ. Việc xóa một bản sao của trình tự lặp 72 cặp bazơ trong vùng promoter SV40 không gây giảm đáng kể trong việc tổng hợp CAT trong các tế bào thận khỉ; tuy nhiên, việc xóa thêm 50 cặp bazơ từ bản sao thứ hai của các trình tự lặp đã làm giảm tổng hợp CAT xuống còn 11% mức của dạng hoang dã. Chúng tôi cũng đã xây dựng một hệ gen tái tổ hợp, pSV0-cat, trong đó toàn bộ vùng promoter SV40 đã bị loại bỏ và một vị trí HindIII độc nhất đã được thay thế để chèn các trình tự promoter khác.\u003C\u002Fjats:p>",{"EN":968,"VI":969},"Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.","Các hệ gen tái tổ hợp biểu hiện enzyme chloramphenicol acetyltransferase trong tế bào động vật có vú.",{"VOID":971},"6960240",{"VOID":973},"10.1128\u002Fmcb.2.9.1044","PUBLICATION","Author affiliation is blank",[118],[117],"http:\u002F\u002Fmcb.asm.org\u002Flookup\u002Fdoi\u002F10.1128\u002FMCB.2.9.1044",[980,989,998],{"id":981,"sortIndex":25,"researcher":24,"roles":982,"affiliations":983,"properties":984,"displayName":986,"givenName":24,"familyName":24},"e39e8601-1c87-4b54-9d96-803c639b390d",[],[],{"title":985,"openalex":987},{"EN":986},"Cornelia M. 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Biochem., 245, 266, 10.1111\u002Fj.1432-1033.1997.00266.x",{"doi":1440},"10.1111\u002Fj.1432-1033.1997.00266.x",{"id":24,"text":1442,"url":24,"identifiers":1443},"10.1073\u002Fpnas.93.22.12142",{"doi":1442},{"id":24,"text":1445,"url":24,"identifiers":1446},"10.1126\u002Fscience.270.5235.484",{"doi":1445},{"id":24,"text":1448,"url":24,"identifiers":1449},"10.1016\u002FS0092-8674(00)81845-0",{"doi":1448},{"id":24,"text":1451,"url":24,"identifiers":1452},"Wilkins M. R., 1997, Proteome research: new frontiers in functional genomics., 10.1007\u002F978-3-662-03493-4",{"doi":1453},"10.1007\u002F978-3-662-03493-4",{"id":24,"text":1455,"url":24,"identifiers":1456},"10.1038\u002F379466a0",{"doi":1455},{"id":24,"text":1458,"url":24,"identifiers":1459},"Yan J. X., 1996, J. Chromatogr. A, 736, 291, 10.1016\u002F0021-9673(95)01285-0",{"doi":1460},"10.1016\u002F0021-9673(95)01285-0",{"id":24,"text":1462,"url":24,"identifiers":1463},"YPD Website. 6 March 1998, revision date. [Online.] Proteome, Inc. http:\u002F\u002Fwww.proteome.com\u002FYPDhome.html [8 January 1999, last date accessed.]",{},{"id":1465,"createTime":1466,"updateTime":1467,"relativeEntities":1468,"slug":1469,"properties":1470,"entityType":974,"verifyStatus":114,"verifyTime":1466,"verifyNote":1092,"languages":1488,"translateLanguages":1489,"viewCount":25,"primaryUrl":1490,"fullTextUrl":24,"authors":1491,"publicationType":1009,"publisherRelationship":1593,"citationCount":1641,"citationInfo":1642,"publishDate":1644,"publishYear":1181,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":1645,"openAccess":24,"references":1646,"isForceReanalyzing":1067},"1a6094a2-6eb9-4d13-b97f-05d631cb3557","2024-09-19T20:21:26.416+00:00","2025-02-13T17:47:14.938+00:00",[],"Firefly-luciferase-gene-structure-and-expression-in-mammalian-cells-",{"mag":1471,"keywords":1473,"pmc":1474,"openalex":1476,"abstract":1478,"title":1481,"pm":1484,"doi":1486},{"VOID":1472},"2097794242",{"VI":959},{"VOID":1475},"365129",{"VOID":1477},"W2097794242",{"EN":1479,"VI":1480},"\u003Cjats:p>The nucleotide sequence of the luciferase gene from the firefly Photinus pyralis was determined from the analysis of cDNA and genomic clones. The gene contains six introns, all less than 60 bases in length. The 5' end of the luciferase mRNA was determined by both S1 nuclease analysis and primer extension. Although the luciferase cDNA clone lacked the six N-terminal codons of the open reading frame, we were able to reconstruct the equivalent of a full-length cDNA using the genomic clone as a source of the missing 5' sequence. The full-length, intronless luciferase gene was inserted into mammalian expression vectors and introduced into monkey (CV-1) cells in which enzymatically active firefly luciferase was transiently expressed. In addition, cell lines stably expressing firefly luciferase were isolated. Deleting a portion of the 5'-untranslated region of the luciferase gene removed an upstream initiation (AUG) codon and resulted in a twofold increase in the level of luciferase expression. The ability of the full-length luciferase gene to activate cryptic or enhancerless promoters was also greatly reduced or eliminated by this 5' deletion. Assaying the expression of luciferase provides a rapid and inexpensive method for monitoring promoter activity. Depending on the instrumentation employed to detect luciferase activity, we estimate this assay to be from 30- to 1,000-fold more sensitive than assaying chloramphenicol acetyltransferase expression.\u003C\u002Fjats:p>","\u003Cjats:p>Chuỗi nucleotide của gen luciferase từ đom đóm Photinus pyralis đã được xác định thông qua phân tích cDNA và các mẫu gen. Gen này chứa sáu intron, tất cả đều có độ dài dưới 60 nucleotid. Đầu 5' của mRNA luciferase đã được xác định thông qua phân tích enzym S1 nuclease và mở rộng mồi. Mặc dù mẫu cDNA luciferase thiếu sáu mã di truyền N-đầu của khung đọc mở, chúng tôi đã có thể tái tạo lại tương đương với cDNA toàn bộ chiều dài bằng cách sử dụng mẫu gen như nguồn để lấy đoạn 5' còn thiếu. Gen luciferase toàn bộ chiều dài, không có intron đã được chèn vào các vector biểu hiện ở động vật có vú và được đưa vào các tế bào khỉ (CV-1) trong đó luciferase của đom đóm hoạt động enzym đã được biểu hiện tạm thời. Ngoài ra, các dòng tế bào biểu hiện luciferase đom đóm một cách ổn định đã được phân lập. Việc xóa một phần của vùng không dịch mã 5'-của gen luciferase đã loại bỏ một mã khởi đầu (AUG) nằm ở phía thượng lưu và dẫn đến sự gia tăng gấp đôi mức độ biểu hiện luciferase. Khả năng của gen luciferase toàn bộ chiều dài trong việc kích hoạt các promoter ẩn hoặc không có enhancer cũng bị suy giảm hoặc loại bỏ bởi việc xóa 5' này. Việc xét nghiệm biểu hiện luciferase cung cấp một phương pháp nhanh chóng và chi phí thấp để theo dõi hoạt động của các promoter. Tùy thuộc vào thiết bị được sử dụng để phát hiện hoạt động luciferase, chúng tôi ước tính rằng phương pháp thử nghiệm này nhạy hơn từ 30 đến 1,000 lần so với xét nghiệm biểu hiện acetyltransferase chloramphenicol.\u003C\u002Fjats:p>",{"EN":1482,"VI":1483},"Firefly luciferase gene: structure and expression in mammalian cells.","Gen luciferase của đom đóm: cấu trúc và biểu hiện trong tế bào động vật có vú.",{"VOID":1485},"3821727",{"VOID":1487},"10.1128\u002Fmcb.7.2.725",[118],[117],"http:\u002F\u002Fmcb.asm.org\u002Flookup\u002Fdoi\u002F10.1128\u002FMCB.7.2.725",[1492,1517,1534,1549,1570],{"id":1493,"sortIndex":25,"researcher":24,"roles":1494,"affiliations":1495,"properties":1512,"displayName":1514,"givenName":24,"familyName":24},"c86727aa-8708-4d59-b147-10f6c12cfbf4",[],[1496,1504],{"id":1497,"sortIndex":25,"affiliation":1498,"properties":24},"9b69dcb4-ca9e-4e72-bc2e-09fe2bac2fa4",{"id":1497,"createTime":24,"updateTime":24,"relativeEntities":1499,"slug":24,"properties":1500,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1503,"statistic":24},[],{"title":1501},{"EN":1502},"Department of Biological Sciences, Stanford University, Stanford, CA 94305.",[],{"id":1505,"sortIndex":126,"affiliation":1506,"properties":24},"947553ae-b529-4752-8c74-48df97fdd9dc",{"id":1505,"createTime":24,"updateTime":24,"relativeEntities":1507,"slug":24,"properties":1508,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1511,"statistic":24},[],{"title":1509},{"EN":1510},"Departments of Biology' and Chemistry,",[],{"title":1513,"openalex":1515},{"EN":1514},"Jeffrey R. de Wet",{"VOID":1516},"A5012044614",{"id":1518,"sortIndex":126,"researcher":24,"roles":1519,"affiliations":1520,"properties":1529,"displayName":1531,"givenName":24,"familyName":24},"cedf4f44-4af4-4cf1-be1e-6e258e8880d4",[],[1521],{"id":1522,"sortIndex":25,"affiliation":1523,"properties":24},"5b585b9b-48de-42ca-9324-9482c14d1b33",{"id":1522,"createTime":24,"updateTime":24,"relativeEntities":1524,"slug":24,"properties":1525,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1528,"statistic":24},[],{"title":1526},{"VI":1527},"University of California, San Diego, La Jolla, California 92093",[],{"title":1530,"openalex":1532},{"EN":1531},"Keith V. 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Five of these antibodies precipitate p62c-myc from human cells, and three of these five also recognize the mouse c-myc gene product. None of the antibodies sees the chicken p110gag-myc protein. All six antibodies recognize immunoblotted p62c-myc. These reagents also provide the basis for an immunoblotting assay by which to quantitate p62c-myc in cells.\u003C\u002Fjats:p>","\u003Cjats:p>Sáu kháng thể đơn dòng đã được tách chiết từ chuột được miễn dịch với các kháng nguyên peptide tổng hợp, có trình tự được lấy từ sản phẩm của gen c-myc ở người. Năm trong số các kháng thể này kết tụ p62c-myc từ các tế bào của người, và ba trong số năm kháng thể này cũng nhận diện sản phẩm gen c-myc ở chuột. Không có kháng thể nào phát hiện được protein p110gag-myc ở gà. Tất cả sáu kháng thể đều nhận diện p62c-myc trên màng miễn dịch. Các thuốc thử này cũng cung cấp cơ sở cho một thử nghiệm miễn dịch để định lượng p62c-myc trong các tế bào.\u003C\u002Fjats:p>",{"EN":1665,"VI":1666},"Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.","Cách ly các kháng thể đơn dòng đặc hiệu cho sản phẩm gen tiền ung thư c-myc của người.",{"VOID":1668},"3915782",{"VOID":1670},"10.1128\u002Fmcb.5.12.3610",[118],[117],"http:\u002F\u002Fmcb.asm.org\u002Flookup\u002Fdoi\u002F10.1128\u002FMCB.5.12.3610",[1675,1694,1711,1728],{"id":1676,"sortIndex":25,"researcher":24,"roles":1677,"affiliations":1678,"properties":1687,"displayName":1691,"givenName":24,"familyName":24},"159af566-ff68-46e4-b1d0-aa9e9eb26659",[],[1679],{"id":1680,"sortIndex":25,"affiliation":1681,"properties":24},"81188dfc-b1ac-4ea0-ac92-53193498e405",{"id":1680,"createTime":24,"updateTime":24,"relativeEntities":1682,"slug":24,"properties":1683,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1686,"statistic":24},[],{"title":1684},{"VI":1685},"University of California at San Francisco",[],{"orcid":1688,"title":1690,"openalex":1692},{"VOID":1689},"https:\u002F\u002Forcid.org\u002F0000-0003-0412-1216",{"EN":1691},"Gérard I. 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Nucleotides (nt) 1 to 33 of this sequence mediate sevenfold induction of reporter gene expression when present in two tandem copies compared with threefold induction when present in a single copy, suggesting that nt 34 to 50 bind a factor which amplifies the induction signal. DNase I footprinting demonstrated binding of a constitutive nuclear factor to nt 26 to 48. Mutagenesis studies revealed that nt 4 to 12 and 19 to 23 are essential for induction, as substitutions at either site eliminated hypoxia-induced expression. Electrophoretic mobility shift assays identified a nuclear factor which bound to a probe spanning nt 1 to 18 but not to a probe containing a mutation which eliminated enhancer function. Factor binding was induced by hypoxia, and its induction was sensitive to cycloheximide treatment. 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Phân tích dấu vết DNase I đã chứng minh sự gắn kết của một yếu tố hạt nhân cấu trúc với các nt từ 26 đến 48. Các nghiên cứu đột biến đã chỉ ra rằng các nt từ 4 đến 12 và từ 19 đến 23 là thiết yếu cho việc kích thích, vì việc thay thế tại bất kỳ vị trí nào đã loại bỏ biểu hiện do thiếu oxy. Các thử nghiệm dịch chuyển di electrophoretic đã xác định một yếu tố hạt nhân gắn với một đầu dò bao gồm các nt từ 1 đến 18 nhưng không gắn với một đầu dò chứa một đột biến đã vô hiệu hóa chức năng tăng cường. Việc gắn kết của yếu tố này đã được kích thích bởi thiếu oxy và sự kích thích này nhạy cảm với điều trị cycloheximide. Chúng tôi đã định nghĩa một yếu tố tăng cường có chức năng ba phần, dài 50 nt, có thể kích thích bởi thiếu oxy và gắn kết với một số yếu tố hạt nhân, một trong số đó được kích thích bởi thiếu oxy thông qua tổng hợp protein mới.\u003C\u002Fjats:p>",{"EN":1818,"VI":1819},"A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.","Một yếu tố nhân tế bào được kích thích bởi thiếu oxy thông qua tổng hợp protein mới gắn vào yếu tố tăng cường gen erythropoietin của người tại một vị trí cần thiết cho hoạt hóa phiên mã.",{"VOID":1821},"1448077",{"VOID":1823},"10.1128\u002Fmcb.12.12.5447",[118],[117],"http:\u002F\u002Fmcb.asm.org\u002Flookup\u002Fdoi\u002F10.1128\u002FMCB.12.12.5447",[1828,1847],{"id":1829,"sortIndex":25,"researcher":24,"roles":1830,"affiliations":1831,"properties":1840,"displayName":1844,"givenName":24,"familyName":24},"60679114-b5b4-4ae7-a6aa-7dd947eb2904",[],[1832],{"id":1833,"sortIndex":25,"affiliation":1834,"properties":24},"77a56f61-ceec-449a-8be3-53d7166e6be2",{"id":1833,"createTime":24,"updateTime":24,"relativeEntities":1835,"slug":24,"properties":1836,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1839,"statistic":24},[],{"title":1837},{"VI":1838},"Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205",[],{"orcid":1841,"title":1843,"openalex":1845},{"VOID":1842},"https:\u002F\u002Forcid.org\u002F0000-0002-0913-211X",{"EN":1844},"Gregg L. 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