[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_fdf3c0c6-72aa-44c5-a5c9-6edbd425d014":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:fdf3c0c6-72aa-44c5-a5c9-6edbd425d014,\"}":117},{"code":4,"data":5,"meta":24},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":26,"manageAffiliations":51,"indexDatabases":74,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},"fdf3c0c6-72aa-44c5-a5c9-6edbd425d014","2023-05-29T11:41:21.276+00:00","2025-11-21T10:02:31.708+00:00",[],"Journal-of-the-Pediatric-Infectious-Diseases-Society",{"country":12,"issn":14,"introduce":16,"eissn":18,"title":20},{"VOID":13},"US",{"VOID":15},"20487207",{"EN":17},"The Journal of the Pediatric Infectious Diseases Society (JPIDS), the official journal of the Pediatric Infectious Diseases Society, is dedicated to perinatal, childhood, and adolescent infectious diseases. The journal is a high-quality source of original research articles, clinical trial reports, guidelines, and topical reviews, with particular attention to the interests and needs of the global pediatric infectious diseases communities. The journal's first and current (2017) Impact Factor is 2.456.",{"VOID":19},"20487193",{"EN":21},"Journal of the Pediatric Infectious Diseases Society","PUBLISHER","PENDING",null,0,[27,35,43],{"id":28,"createTime":29,"updateTime":30,"relativeEntities":31,"label":32,"description":34,"parentId":24,"standard":24,"scholarHubFieldId":24},"5870d53f-1c88-45cf-b26b-c48667a544de","2023-05-29T10:24:16.733+00:00","2023-11-21T08:03:07.275+00:00",[],{"EN":33},"Pediatrics, Perinatology and Child Health",{},{"id":36,"createTime":37,"updateTime":38,"relativeEntities":39,"label":40,"description":42,"parentId":24,"standard":24,"scholarHubFieldId":24},"837c26ad-ce88-445d-9621-a6d173c82561","2023-05-29T10:24:05.503+00:00","2023-11-21T06:25:15.160+00:00",[],{"EN":41},"Infectious Diseases",{},{"id":44,"createTime":45,"updateTime":46,"relativeEntities":47,"label":48,"description":50,"parentId":24,"standard":24,"scholarHubFieldId":24},"0254e3e5-c28d-4a33-83da-81bc94d29ffd","2023-05-29T10:24:00.931+00:00","2023-11-21T07:56:41.438+00:00",[],{"EN":49},"Medicine (miscellaneous)",{},[52,64],{"id":53,"createTime":54,"updateTime":55,"relativeEntities":56,"slug":57,"properties":58,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":62,"url":24,"parentIds":63,"statistic":24},"2bc101c3-b2fa-462b-9498-b1c3a2f9ba51","2023-05-29T12:08:02.996+00:00","2024-02-18T12:06:12.696+00:00",[],"OXFORD-UNIV-PRESS",{"title":59},{"EN":60},"OXFORD UNIV PRESS","AFFILIATION",4,[],{"id":65,"createTime":66,"updateTime":67,"relativeEntities":68,"slug":69,"properties":70,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":62,"url":24,"parentIds":73,"statistic":24},"3b2b3c1e-d793-4160-89dd-eb4e42b70e4a","2023-05-29T10:24:01.308+00:00","2025-11-21T10:07:42.786+00:00",[],"Oxford-University-Press",{"title":71},{"EN":72},"Oxford University Press",[],[75,95],{"id":76,"indexDatabase":77,"url":91,"indexYears":24,"academicFieldIds":92,"indexDatabaseRanking":24},"30c58796-0b51-4642-ac1f-d8581b908338",{"id":78,"createTime":79,"updateTime":80,"relativeEntities":81,"label":82,"description":84,"key":87,"publicationTags":88,"standard":24},"a4921856-b128-4d9f-8f1f-e80813d3bbd4","2023-05-22T09:59:31.026+00:00","2025-11-21T10:07:52.153+00:00",[],{"EN":83,"VI":83},"ISI\u002FSCIE - Science Citation Index Expanded",{"VI":85,"EN":86},"Cơ sở dữ liệu SCIE","SCIE database","scie",[89,90],"SCIE","ISI","https:\u002F\u002Fmjl.clarivate.com\u002Fsearch-results?issn=2048-7193",[93,94],"5f55e015-9add-4a50-bbdf-b4dbac2e40b3","53866f02-5006-4f8f-a807-ec8cf950fc52",{"id":96,"indexDatabase":97,"url":109,"indexYears":110,"academicFieldIds":111,"indexDatabaseRanking":115},"3e3157f2-a391-4905-8849-6374a422e082",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":101,"label":102,"description":104,"key":106,"publicationTags":107,"standard":24},"3c7051d4-eb7d-4c57-a56b-36fc74c5d1e9","2023-05-22T09:57:18.509+00:00","2025-11-21T10:07:52.274+00:00",[],{"EN":103,"VI":103},"Scopus - Elsevier",{"EN":103,"VI":105},"Cơ sở dữ liệu Scopus thuộc Elsevier","scopus",[108],"SCOPUS","https:\u002F\u002Fwww.scopus.com\u002Fsourceid\u002F21100428207","2012-2025",[112,113,114],"2a49c7d8-bbba-4081-b827-942cc7f24661","e89cebf4-fecf-4b74-8ab4-88fca891e4c2","1a7c8bc3-0575-4f8d-b22c-aec346a0168a","SCOPUS__Q1","https:\u002F\u002Facademic.oup.com\u002Fjpids",{"meta":118,"data":120},{"total":119},"11",[121,463,848,1085,1387,1696,1932,2420,3826,5136],{"id":122,"createTime":123,"updateTime":123,"relativeEntities":124,"slug":125,"properties":126,"entityType":141,"verifyStatus":142,"verifyTime":123,"verifyNote":143,"syncStatus":23,"languages":144,"translateLanguages":24,"viewCount":25,"primaryUrl":146,"fullTextUrl":24,"authors":147,"publicationType":398,"publisherRelationship":399,"citationCount":432,"citationInfo":433,"publishDate":438,"publishYear":439,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":440,"isForceReanalyzing":462},"cdd10d7d-3f8a-4a38-87b2-ce47b4e0123d","2024-09-20T23:36:41.300+00:00",[],"COVID-19-Associated-Pediatric-Multisystem-Inflammatory-Syndrome",{"mag":127,"keywords":129,"pmc":130,"openalex":132,"abstract":134,"title":135,"pm":137,"doi":139},{"VOID":128},"3027822235",{},{"VOID":131},"7313914",{"VOID":133},"W3027822235",{},{"EN":136},"COVID-19–Associated Pediatric Multisystem Inflammatory Syndrome",{"VOID":138},"32441749",{"VOID":140},"10.1093\u002Fjpids\u002Fpiaa061","PUBLICATION","VERIFIED","Auto Verify",[145],"EN","https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F9\u002F3\u002F407\u002F5842067",[148,183,207,231,255,270,292,320,335,352,374],{"id":149,"sortIndex":150,"researcher":24,"roles":151,"affiliations":152,"properties":176},"93d99626-55ca-44e4-a64b-5776cea5b103",8,[],[153,164],{"id":154,"sortIndex":25,"affiliation":155,"properties":24},"153c0960-9cea-4e39-9a50-c7de3fcd94b8",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":159,"slug":160,"properties":161,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"f5231d0b-47ee-4c89-8618-726a643d0fcf","2023-12-11T15:13:53.766+00:00","2024-10-12T19:36:26.336+00:00",[],"Children-s-Hospital-of-Michigan-Detroit-Michigan-USA",{"title":162},{"VI":163},"Children’s Hospital of Michigan, Detroit, Michigan, USA",{"id":165,"sortIndex":166,"affiliation":167,"properties":24},"0dfef854-6bf2-474e-a3d7-bc962821e513",1,{"id":168,"createTime":169,"updateTime":170,"relativeEntities":171,"slug":172,"properties":173,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6adf3fe6-14bf-4c8b-914b-4e0fe3e1ae81","2024-09-20T23:36:41.351+00:00","2024-09-28T16:58:37.070+00:00",[],"Wayne-State-University-School-of-Medicine-Department-of-Pediatrics-Detroit-Michigan-USA",{"title":174},{"EN":175},"Wayne State University School of Medicine, Department of Pediatrics, Detroit, Michigan, USA",{"openalex":177,"orcid":179,"title":181},{"VOID":178},"A5025731578",{"VOID":180},"https:\u002F\u002Forcid.org\u002F0000-0001-8393-2863",{"EN":182},"Harbir Arora",{"id":184,"sortIndex":185,"researcher":24,"roles":186,"affiliations":187,"properties":200},"24470bff-2a51-4c91-a03f-f9b20e8f7763",9,[],[188,194],{"id":189,"sortIndex":166,"affiliation":190,"properties":24},"8cb0a50b-816e-4b7f-aa34-d2c4f536da70",{"id":168,"createTime":169,"updateTime":170,"relativeEntities":191,"slug":172,"properties":192,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":193},{"EN":175},{"id":195,"sortIndex":25,"affiliation":196,"properties":24},"23654ee3-6188-4d5e-bd55-8a38974979d0",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":197,"slug":160,"properties":198,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":199},{"VI":163},{"openalex":201,"orcid":203,"title":205},{"VOID":202},"A5078156253",{"VOID":204},"https:\u002F\u002Forcid.org\u002F0000-0002-3286-5418",{"EN":206},"Jocelyn Y. Ang",{"id":208,"sortIndex":209,"researcher":24,"roles":210,"affiliations":211,"properties":224},"9e15d773-9f2e-4778-a388-f8167458f465",2,[],[212,218],{"id":213,"sortIndex":25,"affiliation":214,"properties":24},"194cedb6-483a-4dc6-90fb-ac99474e9c96",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":215,"slug":160,"properties":216,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":217},{"VI":163},{"id":219,"sortIndex":166,"affiliation":220,"properties":24},"d95568d2-b9ee-44d2-80c7-f7316558eefa",{"id":168,"createTime":169,"updateTime":170,"relativeEntities":221,"slug":172,"properties":222,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":223},{"EN":175},{"openalex":225,"orcid":227,"title":229},{"VOID":226},"A5031259367",{"VOID":228},"https:\u002F\u002Forcid.org\u002F0000-0003-1542-6488",{"EN":230},"Eric McGrath",{"id":232,"sortIndex":233,"researcher":24,"roles":234,"affiliations":235,"properties":248},"e6637dd2-aa32-4a63-9474-c560820f284d",3,[],[236,242],{"id":237,"sortIndex":25,"affiliation":238,"properties":24},"64e1127e-8dc6-443d-a7c8-c71e3c20b149",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":239,"slug":160,"properties":240,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":241},{"VI":163},{"id":243,"sortIndex":166,"affiliation":244,"properties":24},"5c61a5cf-4d16-411c-b8e6-bd43286ab1b1",{"id":168,"createTime":169,"updateTime":170,"relativeEntities":245,"slug":172,"properties":246,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":247},{"EN":175},{"openalex":249,"orcid":251,"title":253},{"VOID":250},"A5012117998",{"VOID":252},"https:\u002F\u002Forcid.org\u002F0000-0001-6957-4756",{"EN":254},"Nahed Abdel‐Haq",{"id":256,"sortIndex":166,"researcher":24,"roles":257,"affiliations":258,"properties":265},"6130999c-af59-4143-b2f0-9efd58592090",[],[259],{"id":260,"sortIndex":25,"affiliation":261,"properties":24},"e4255904-864b-43ba-81f9-d79c74632fcf",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":262,"slug":160,"properties":263,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":264},{"VI":163},{"openalex":266,"title":268},{"VOID":267},"A5037338626",{"EN":269},"Ajla Redzepi",{"id":271,"sortIndex":272,"researcher":24,"roles":273,"affiliations":274,"properties":285},"4e7fca10-2513-4b08-93d6-8a422c03df85",7,[],[275],{"id":276,"sortIndex":25,"affiliation":277,"properties":24},"8744f2a7-a0ff-48cc-9aec-7acb1acd4bec",{"id":278,"createTime":279,"updateTime":279,"relativeEntities":280,"slug":281,"properties":282,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"a43ecd5c-9f8b-4383-b966-707b7e136f84","2024-09-20T23:36:41.395+00:00",[],"Wayne-State-University-School-of-Medicine-Department-of-Internal-Medicine-Detroit-Michigan-USA",{"title":283},{"EN":284},"Wayne State University School of Medicine, Department of Internal Medicine, Detroit, Michigan, USA",{"openalex":286,"orcid":288,"title":290},{"VOID":287},"A5077066823",{"VOID":289},"https:\u002F\u002Forcid.org\u002F0000-0003-1185-4549",{"EN":291},"Teena Chopra",{"id":293,"sortIndex":294,"researcher":24,"roles":295,"affiliations":296,"properties":313},"cc032997-1680-41d7-afc0-f89cc10c5bc7",6,[],[297,303],{"id":298,"sortIndex":166,"affiliation":299,"properties":24},"6d5f6914-d7b8-4cdc-b4e0-a8a675915ad4",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":300,"slug":160,"properties":301,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":302},{"VI":163},{"id":304,"sortIndex":25,"affiliation":305,"properties":24},"8860a668-a44b-47bc-8c71-828d05d1f481",{"id":306,"createTime":307,"updateTime":307,"relativeEntities":308,"slug":309,"properties":310,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"53e4e28a-842b-42b9-8835-4c5d40185313","2024-09-20T23:36:41.382+00:00",[],"Central-Michigan-University-College-of-Medicine-Department-of-Pediatrics-Mount-Pleasant-Michigan-USA",{"title":311},{"EN":312},"Central Michigan University College of Medicine, Department of Pediatrics, Mount Pleasant, Michigan, USA",{"openalex":314,"orcid":316,"title":318},{"VOID":315},"A5037096881",{"VOID":317},"https:\u002F\u002Forcid.org\u002F0000-0001-8823-4028",{"EN":319},"Bradley Tilford",{"id":321,"sortIndex":62,"researcher":24,"roles":322,"affiliations":323,"properties":330},"b80f19ac-37a9-41fe-8000-ecc58ff8b7bb",[],[324],{"id":325,"sortIndex":25,"affiliation":326,"properties":24},"ddb94347-8a7f-4ac1-86b6-f60b34f95c93",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":327,"slug":160,"properties":328,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":329},{"VI":163},{"openalex":331,"title":333},{"VOID":332},"A5027641052",{"EN":334},"Ahmed Shawaqfeh",{"id":336,"sortIndex":25,"researcher":24,"roles":337,"affiliations":338,"properties":345},"9b1958e0-1fc9-4cb4-85ea-3e37df88c102",[],[339],{"id":340,"sortIndex":25,"affiliation":341,"properties":24},"c57b9026-217c-486d-9114-b800bb8bf523",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":342,"slug":160,"properties":343,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":344},{"VI":163},{"openalex":346,"orcid":348,"title":350},{"VOID":347},"A5023332258",{"VOID":349},"https:\u002F\u002Forcid.org\u002F0000-0003-0245-2177",{"EN":351},"Maria Deza Leon",{"id":353,"sortIndex":354,"researcher":24,"roles":355,"affiliations":356,"properties":369},"4e077fce-c41b-4293-81e3-787d0c281d1f",10,[],[357,363],{"id":358,"sortIndex":25,"affiliation":359,"properties":24},"f6aa3afa-2096-4e24-8a82-5d8189f0e2d3",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":360,"slug":160,"properties":361,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":362},{"VI":163},{"id":364,"sortIndex":166,"affiliation":365,"properties":24},"a5374be8-ada8-47bd-b4ca-ba061378849d",{"id":168,"createTime":169,"updateTime":170,"relativeEntities":366,"slug":172,"properties":367,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":368},{"EN":175},{"openalex":370,"title":372},{"VOID":371},"A5038768711",{"EN":373},"Basim I. Asmar",{"id":375,"sortIndex":376,"researcher":24,"roles":377,"affiliations":378,"properties":391},"a3751275-fc3d-4fd6-9249-e56fc9a12726",5,[],[379,385],{"id":380,"sortIndex":25,"affiliation":381,"properties":24},"44b69cb7-6c56-4795-bc33-2972a0f26b47",{"id":156,"createTime":157,"updateTime":158,"relativeEntities":382,"slug":160,"properties":383,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":384},{"VI":163},{"id":386,"sortIndex":166,"affiliation":387,"properties":24},"1ab61e0e-c165-42ef-989e-6c0b924f501f",{"id":168,"createTime":169,"updateTime":170,"relativeEntities":388,"slug":172,"properties":389,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":390},{"EN":175},{"openalex":392,"orcid":394,"title":396},{"VOID":393},"A5019031588",{"VOID":395},"https:\u002F\u002Forcid.org\u002F0000-0002-5183-0325",{"EN":397},"Usha Sethuraman","ARTICLE",{"url":24,"publisher":400,"properties":425},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":401,"slug":10,"properties":402,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":408,"manageAffiliations":409,"indexDatabases":410,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":403,"issn":404,"introduce":405,"eissn":406,"title":407},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[411,418],{"id":76,"indexDatabase":412,"url":91,"indexYears":24,"academicFieldIds":417,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":413,"label":414,"description":415,"key":87,"publicationTags":416,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":419,"url":109,"indexYears":110,"academicFieldIds":424,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":420,"label":421,"description":422,"key":106,"publicationTags":423,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":426,"pages":428,"issue":430},{"VOID":427},"9",{"VOID":429},"407-408",{"VOID":431},"3",117,{"total":432,"publishYear":24,"statisticByYear":434},{"2020":435,"2021":436,"2022":437,"2023":185,"2024":233},36,45,23,"2020-07-13",2020,[441,444,448,452,455,459],{"id":24,"text":442,"url":24,"identifiers":443},"Woodyatt, 2020, What Is Kawasaki Disease? The Rare Child Syndrome Might Have Link to Covid-19",{},{"id":24,"text":445,"url":24,"identifiers":446},"Ludvigsson, 2020, Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults, Acta Paediatr, 109, 1088, 10.1111\u002Fapa.15270",{"doi":447},"10.1111\u002Fapa.15270",{"id":24,"text":449,"url":24,"identifiers":450},"She, 2020, COVID-19 epidemic: disease characteristics in children, J Med Virol, 10.1002\u002Fjmv.25807",{"doi":451},"10.1002\u002Fjmv.25807",{"id":24,"text":453,"url":24,"identifiers":454},"Dong, 2020, Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China, Pediatrics",{},{"id":24,"text":456,"url":24,"identifiers":457},"Cruz, 2020, COVID-19 in children: initial characterization of the pediatric disease, Pediatrics, 10.1542\u002Fpeds.2020-0834",{"doi":458},"10.1542\u002Fpeds.2020-0834",{"id":24,"text":460,"url":24,"identifiers":461},"Centers for Disease Control and Prevention COVID-19 Response Team, 2020, Coronavirus disease 2019 in children—United States, February 12–April 2, 2020, MMWE Morb Mortal Wkly Rep",{},false,{"id":464,"createTime":465,"updateTime":465,"relativeEntities":466,"slug":467,"properties":468,"entityType":141,"verifyStatus":142,"verifyTime":465,"verifyNote":143,"syncStatus":23,"languages":484,"translateLanguages":24,"viewCount":25,"primaryUrl":485,"fullTextUrl":24,"authors":486,"publicationType":398,"publisherRelationship":760,"citationCount":792,"citationInfo":793,"publishDate":795,"publishYear":439,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":796,"isForceReanalyzing":462},"a53e2614-ad54-455c-be57-24eb45eae268","2024-09-20T23:34:13.020+00:00",[],"Defibrotide-for-the-Treatment-of-Pediatric-Inflammatory-Multisystem-Syndrome-Temporally-Associated-With-Severe-Acute-Respiratory-Syndrome-Coronavirus-2-Infection-in-2-Pediatric-Patients",{"mag":469,"keywords":471,"pmc":472,"openalex":474,"abstract":476,"title":478,"pm":480,"doi":482},{"VOID":470},"3087069819",{},{"VOID":473},"7543556",{"VOID":475},"W3087069819",{"EN":477},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:p>The pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 infection is a severe complication of coronavirus disease 2019. Since impaired coagulation and thrombosis\u002Fendotheliitis are suspected pathomechanisms, we treated 2 patients with defibrotide, a profibrinolytic, antithrombotic, antiinflammatory oligonucleotide. Symptoms resolved during treatment. Moreover, coagulation parameters indicating hypofibrinolysis and complement activation normalized.\u003C\u002Fjats:p>\u003Cjats:p>The pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 infection is a severe complication of coronavirus disease 2019. Since impaired coagulation and thrombosis\u002Fendotheliitis are suspected pathomechanisms, 2 patients received defibrotide, a profibrinolytic, antithrombotic, antiinflammatory oligonucleotide. Symptoms resolved and hypofibrinolysis\u002Fcomplement activation normalized during treatment.\u003C\u002Fjats:p>",{"EN":479},"Defibrotide for the Treatment of Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 2 Pediatric Patients",{"VOID":481},"32951037",{"VOID":483},"10.1093\u002Fjpids\u002Fpiaa117",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F9\u002F5\u002F622\u002F5909163",[487,506,526,541,562,579,597,618,636,653,674,689,704,726,743],{"id":488,"sortIndex":185,"researcher":24,"roles":489,"affiliations":490,"properties":501},"a5c8c902-cc88-40ee-a590-b760d51ac21a",[],[491],{"id":492,"sortIndex":25,"affiliation":493,"properties":24},"2c27d5ff-6cc6-4808-bcd6-d6b42a2081c6",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":496,"slug":497,"properties":498,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6035712a-043c-4682-8432-ac5cda1c98d6","2024-09-20T23:34:13.074+00:00",[],"Children-s-University-Hospital-Eberhard-Karls-University-Tuebingen-Tuebingen-Germany",{"title":499},{"EN":500},"Children's University Hospital, Eberhard Karls University Tuebingen, Tuebingen, Germany",{"openalex":502,"title":504},{"VOID":503},"A5013059010",{"EN":505},"Constantin Adams",{"id":507,"sortIndex":508,"researcher":24,"roles":509,"affiliations":510,"properties":521},"8e2a5459-45c8-4c08-8ad9-55d31dda3a45",13,[],[511],{"id":512,"sortIndex":25,"affiliation":513,"properties":24},"0cf2b587-4aa2-46f8-9ed8-3c3981ee470c",{"id":514,"createTime":515,"updateTime":515,"relativeEntities":516,"slug":517,"properties":518,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"b7a4511b-9d26-4110-b363-d8d1ea8d2494","2024-09-20T23:34:13.040+00:00",[],"Children-s-Hospital-SLK-Kliniken-Heilbronn-GmbH-Heilbronn-Germany",{"title":519},{"EN":520},"Children's Hospital, SLK-Kliniken Heilbronn GmbH, Heilbronn, Germany",{"openalex":522,"title":524},{"VOID":523},"A5070745730",{"EN":525},"Peter Ruef",{"id":527,"sortIndex":62,"researcher":24,"roles":528,"affiliations":529,"properties":536},"c1f1b5a0-5378-40f3-890b-cf708552bd2b",[],[530],{"id":531,"sortIndex":25,"affiliation":532,"properties":24},"3b41888e-c267-4449-a021-621f5c937859",{"id":514,"createTime":515,"updateTime":515,"relativeEntities":533,"slug":517,"properties":534,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":535},{"EN":520},{"openalex":537,"title":539},{"VOID":538},"A5047249382",{"EN":540},"Maurice Petrasch",{"id":542,"sortIndex":376,"researcher":24,"roles":543,"affiliations":544,"properties":555},"527d1ccd-7001-4316-ac4a-1c7364e2fabc",[],[545],{"id":546,"sortIndex":25,"affiliation":547,"properties":24},"0cd1828c-e319-45c8-906c-89bef2956175",{"id":548,"createTime":549,"updateTime":549,"relativeEntities":550,"slug":551,"properties":552,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"c025452f-176c-4840-8729-2723af9cc029","2024-09-20T23:34:13.117+00:00",[],"Institute-of-Pathology-Eberhard-Karls-University-Tuebingen-Tuebingen-Germany",{"title":553},{"EN":554},"Institute of Pathology, Eberhard Karls University Tuebingen, Tuebingen, Germany",{"openalex":556,"orcid":558,"title":560},{"VOID":557},"A5091849033",{"VOID":559},"https:\u002F\u002Forcid.org\u002F0000-0002-7515-435X",{"EN":561},"Hans Bösmüller",{"id":563,"sortIndex":354,"researcher":24,"roles":564,"affiliations":565,"properties":572},"03b68e85-c311-47da-aca9-3261be115654",[],[566],{"id":567,"sortIndex":25,"affiliation":568,"properties":24},"7fe30c4c-91c1-45cd-a757-3662595bfc2b",{"id":548,"createTime":549,"updateTime":549,"relativeEntities":569,"slug":551,"properties":570,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":571},{"EN":554},{"openalex":573,"orcid":575,"title":577},{"VOID":574},"A5047501668",{"VOID":576},"https:\u002F\u002Forcid.org\u002F0000-0003-0203-2498",{"EN":578},"Karin Klingel",{"id":580,"sortIndex":581,"researcher":24,"roles":582,"affiliations":583,"properties":590},"655471f8-9f33-4df6-9df5-a3bd5ca8aae1",14,[],[584],{"id":585,"sortIndex":25,"affiliation":586,"properties":24},"3f307d2b-311a-44d3-9405-77e3999dd356",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":587,"slug":497,"properties":588,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":589},{"EN":500},{"openalex":591,"orcid":593,"title":595},{"VOID":592},"A5035626095",{"VOID":594},"https:\u002F\u002Forcid.org\u002F0000-0003-1838-8990",{"EN":596},"Rupert Handgretinger",{"id":598,"sortIndex":294,"researcher":24,"roles":599,"affiliations":600,"properties":611},"42cf2d0b-4adb-4814-a488-dc8784a7c8cc",[],[601],{"id":602,"sortIndex":25,"affiliation":603,"properties":24},"d1f3d3d2-ccd5-44d6-9588-1aa570766ff1",{"id":604,"createTime":605,"updateTime":605,"relativeEntities":606,"slug":607,"properties":608,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6500966d-e055-482b-93a4-64abb8946746","2024-09-20T23:34:13.129+00:00",[],"Department-of-Haematology-Oncology-Eberhard-Karls-University-Tuebingen-Tuebingen-Germany",{"title":609},{"EN":610},"Department of Haematology\u002FOncology, Eberhard Karls University Tuebingen, Tuebingen, Germany",{"openalex":612,"orcid":614,"title":616},{"VOID":613},"A5045408805",{"VOID":615},"https:\u002F\u002Forcid.org\u002F0000-0002-6111-3901",{"EN":617},"Reinhild Klein",{"id":619,"sortIndex":620,"researcher":24,"roles":621,"affiliations":622,"properties":629},"f023c28f-5bca-4ac5-a82e-cceebffb14d8",11,[],[623],{"id":624,"sortIndex":25,"affiliation":625,"properties":24},"add289de-6ac3-465a-bd66-019611bf8026",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":626,"slug":497,"properties":627,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":628},{"EN":500},{"openalex":630,"orcid":632,"title":634},{"VOID":631},"A5051955489",{"VOID":633},"https:\u002F\u002Forcid.org\u002F0000-0002-8863-2007",{"EN":635},"Michaela Geßner",{"id":637,"sortIndex":25,"researcher":24,"roles":638,"affiliations":639,"properties":646},"d794e94e-535f-4b1e-b179-b6b43f18592c",[],[640],{"id":641,"sortIndex":25,"affiliation":642,"properties":24},"ce12a8b4-6e15-4f13-b71f-ed0847d58ee2",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":643,"slug":497,"properties":644,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":645},{"EN":500},{"openalex":647,"orcid":649,"title":651},{"VOID":648},"A5061269411",{"VOID":650},"https:\u002F\u002Forcid.org\u002F0000-0001-7737-2142",{"EN":652},"Peter Lang",{"id":654,"sortIndex":209,"researcher":24,"roles":655,"affiliations":656,"properties":667},"120fd945-dc6e-4be5-8003-025085faec42",[],[657],{"id":658,"sortIndex":25,"affiliation":659,"properties":24},"7a845328-cabb-4d51-99bc-1f8a1d3c7bcd",{"id":660,"createTime":661,"updateTime":661,"relativeEntities":662,"slug":663,"properties":664,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"864cfb1c-1cc2-4fe7-bc62-bd31fac6d8ce","2024-09-20T23:34:13.097+00:00",[],"Institute-of-Transfusion-Medicine-Eberhard-Karls-University-Tuebingen-Tuebingen-Germany",{"title":665},{"EN":666},"Institute of Transfusion Medicine, Eberhard Karls University Tuebingen, Tuebingen, Germany",{"openalex":668,"orcid":670,"title":672},{"VOID":669},"A5066897101",{"VOID":671},"https:\u002F\u002Forcid.org\u002F0000-0002-6797-6812",{"EN":673},"Tamam Bakchoul",{"id":675,"sortIndex":233,"researcher":24,"roles":676,"affiliations":677,"properties":684},"37830fcb-de7f-4bbf-a14f-25098d312612",[],[678],{"id":679,"sortIndex":25,"affiliation":680,"properties":24},"7bc0a158-1308-48a9-bc4a-94d06016cc2d",{"id":514,"createTime":515,"updateTime":515,"relativeEntities":681,"slug":517,"properties":682,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":683},{"EN":520},{"openalex":685,"title":687},{"VOID":686},"A5023456092",{"EN":688},"Monika Streiter",{"id":690,"sortIndex":166,"researcher":24,"roles":691,"affiliations":692,"properties":699},"780b8698-4e56-478a-8cd0-5abc022d42bf",[],[693],{"id":694,"sortIndex":25,"affiliation":695,"properties":24},"661b609d-3859-4f07-a0ed-99d8625d4cdb",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":696,"slug":497,"properties":697,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":698},{"EN":500},{"openalex":700,"title":702},{"VOID":701},"A5030489108",{"EN":703},"Thomas Eichholz",{"id":705,"sortIndex":706,"researcher":24,"roles":707,"affiliations":708,"properties":719},"32f3958f-723d-4815-b1c4-b694e8e34222",12,[],[709],{"id":710,"sortIndex":25,"affiliation":711,"properties":24},"0462131b-b572-4209-ba16-0d755a0d5296",{"id":712,"createTime":713,"updateTime":713,"relativeEntities":714,"slug":715,"properties":716,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"409993a9-d568-474c-8dc5-f5763eb48fc7","2024-09-20T23:34:13.162+00:00",[],"University-Hospital-for-Intensive-Care-and-Anaesthesiology-Eberhard-Karls-University-Tuebingen-Tuebingen-Germany",{"title":717},{"EN":718},"University Hospital for Intensive Care and Anaesthesiology, Eberhard Karls University Tuebingen, Tuebingen, Germany",{"openalex":720,"orcid":722,"title":724},{"VOID":721},"A5101854584",{"VOID":723},"https:\u002F\u002Forcid.org\u002F0000-0001-5371-139X",{"EN":725},"Peter Rosenberger",{"id":727,"sortIndex":272,"researcher":24,"roles":728,"affiliations":729,"properties":736},"d443f565-5290-416d-802c-3ac3e091565c",[],[730],{"id":731,"sortIndex":25,"affiliation":732,"properties":24},"67feebbc-bbca-4fe3-9395-4318e0ad118e",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":733,"slug":497,"properties":734,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":735},{"EN":500},{"openalex":737,"orcid":739,"title":741},{"VOID":738},"A5085043223",{"VOID":740},"https:\u002F\u002Forcid.org\u002F0000-0002-0553-2693",{"EN":742},"Armin Rabsteyn",{"id":744,"sortIndex":150,"researcher":24,"roles":745,"affiliations":746,"properties":753},"348aa40f-1b81-4cb1-9582-e97b0da8ee1b",[],[747],{"id":748,"sortIndex":25,"affiliation":749,"properties":24},"c3af0f1b-9dde-40b0-95f1-3a3ee098a996",{"id":494,"createTime":495,"updateTime":495,"relativeEntities":750,"slug":497,"properties":751,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":752},{"EN":500},{"openalex":754,"orcid":756,"title":758},{"VOID":755},"A5013682083",{"VOID":757},"https:\u002F\u002Forcid.org\u002F0000-0002-6539-9476",{"EN":759},"Annemarie Lang",{"url":24,"publisher":761,"properties":786},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":762,"slug":10,"properties":763,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":769,"manageAffiliations":770,"indexDatabases":771,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":764,"issn":765,"introduce":766,"eissn":767,"title":768},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[772,779],{"id":76,"indexDatabase":773,"url":91,"indexYears":24,"academicFieldIds":778,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":774,"label":775,"description":776,"key":87,"publicationTags":777,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":780,"url":109,"indexYears":110,"academicFieldIds":785,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":781,"label":782,"description":783,"key":106,"publicationTags":784,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":787,"pages":788,"issue":790},{"VOID":427},{"VOID":789},"622-625",{"VOID":791},"5",15,{"total":792,"publishYear":24,"statisticByYear":794},{"2021":185,"2022":62,"2023":166,"2024":166},"2020-11-10",[797,801,805,809,813,817,821,825,829,833,837,841,845],{"id":24,"text":798,"url":24,"identifiers":799},"Goh, 2020, Rapid progression to acute respiratory distress syndrome: review of current understanding of critical illness from COVID-19 infection, Ann Acad Med Singap, 49, 108, 10.47102\u002Fannals-acadmedsg.202057",{"doi":800},"10.47102\u002Fannals-acadmedsg.202057",{"id":24,"text":802,"url":24,"identifiers":803},"Tang, 2020, Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia, J Thromb Haemost, 18, 844, 10.1111\u002Fjth.14768",{"doi":804},"10.1111\u002Fjth.14768",{"id":24,"text":806,"url":24,"identifiers":807},"Varga, 2020, Endothelial cell infection and endotheliitis in COVID-19, Lancet, 395, 1417, 10.1016\u002FS0140-6736(20)30937-5",{"doi":808},"10.1016\u002FS0140-6736(20)30937-5",{"id":24,"text":810,"url":24,"identifiers":811},"Riphagen, 2020, Hyperinflammatory shock in children during COVID-19 pandemic, Lancet, 395, 1607, 10.1016\u002FS0140-6736(20)31094-1",{"doi":812},"10.1016\u002FS0140-6736(20)31094-1",{"id":24,"text":814,"url":24,"identifiers":815},"Carreras, 2011, The role of the endothelium in the short-term complications of hematopoietic SCT, Bone Marrow Transplant, 46, 1495, 10.1038\u002Fbmt.2011.65",{"doi":816},"10.1038\u002Fbmt.2011.65",{"id":24,"text":818,"url":24,"identifiers":819},"Richardson, 2013, Drug safety evaluation of defibrotide, Expert Opin Drug Saf, 12, 123, 10.1517\u002F14740338.2012.749855",{"doi":820},"10.1517\u002F14740338.2012.749855",{"id":24,"text":822,"url":24,"identifiers":823},"Pescador, 2013, Defibrotide: properties and clinical use of an old\u002Fnew drug, Vascul Pharmacol, 59, 1, 10.1016\u002Fj.vph.2013.05.001",{"doi":824},"10.1016\u002Fj.vph.2013.05.001",{"id":24,"text":826,"url":24,"identifiers":827},"Shekerdemian, 2020, Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units, JAMA Pediatr, 10.1001\u002Fjamapediatrics.2020.1948",{"doi":828},"10.1001\u002Fjamapediatrics.2020.1948",{"id":24,"text":830,"url":24,"identifiers":831},"Feldstein, 2020, Multisystem inflammatory syndrome in U.S. children and adolescents, N Engl J Med, 383, 334, 10.1056\u002FNEJMoa2021680",{"doi":832},"10.1056\u002FNEJMoa2021680",{"id":24,"text":834,"url":24,"identifiers":835},"Wang, 2015, The role of C5a in acute lung injury induced by highly pathogenic viral infections, Emerg Microbes Infect, 4, e28, 10.1038\u002Femi.2015.28",{"doi":836},"10.1038\u002Femi.2015.28",{"id":24,"text":838,"url":24,"identifiers":839},"Magro, 2020, Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases, Transl Res, 220, 1, 10.1016\u002Fj.trsl.2020.04.007",{"doi":840},"10.1016\u002Fj.trsl.2020.04.007",{"id":24,"text":842,"url":24,"identifiers":843},"Zhang, 2020, Immune phenotyping based on neutrophil-to-lymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19, Front Mol Biosci, 10.3389\u002Ffmolb.2020.00157",{"doi":844},"10.3389\u002Ffmolb.2020.00157",{"id":24,"text":846,"url":24,"identifiers":847},"Klok, 2020, Incidence of thrombotic complications in critically ill ICU patients with COVID-19, Thromb Res",{},{"id":849,"createTime":850,"updateTime":850,"relativeEntities":851,"slug":852,"properties":853,"entityType":141,"verifyStatus":142,"verifyTime":850,"verifyNote":143,"syncStatus":23,"languages":868,"translateLanguages":24,"viewCount":25,"primaryUrl":869,"fullTextUrl":24,"authors":870,"publicationType":398,"publisherRelationship":961,"citationCount":993,"citationInfo":994,"publishDate":996,"publishYear":997,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":998,"isForceReanalyzing":462},"bc16bef0-57d3-4e7f-88ac-a1c0ceec1251","2024-11-25T21:17:44.337+00:00",[],"Shiga-Toxin-Producing-i-Escherichia-coli-i-in-Diarrheal-Stool-of-Swedish-Children-Evaluation-of-Polymerase-Chain-Reaction-Screening-and-Duration-of-Shiga-Toxin-Shedding",{"mag":854,"keywords":856,"pmc":857,"openalex":859,"abstract":861,"title":862,"pm":864,"doi":866},{"VOID":855},"2111229628",{},{"VOID":858},"5407124",{"VOID":860},"W2111229628",{},{"EN":863},"Shiga Toxin-Producing\u003Ci>Escherichia coli\u003C\u002Fi>in Diarrheal Stool of Swedish Children: Evaluation of Polymerase Chain Reaction Screening and Duration of Shiga Toxin Shedding",{"VOID":865},"27199470",{"VOID":867},"10.1093\u002Fjpids\u002Fpiv003",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle-lookup\u002Fdoi\u002F10.1093\u002Fjpids\u002Fpiv003",[871,890,910,925,944],{"id":872,"sortIndex":233,"researcher":24,"roles":873,"affiliations":874,"properties":885},"9cfdcc69-01f4-4d9b-becf-8e68478f7d90",[],[875],{"id":876,"sortIndex":25,"affiliation":877,"properties":24},"6a01979b-aa1f-4232-8cb5-21165ac6470c",{"id":878,"createTime":879,"updateTime":879,"relativeEntities":880,"slug":881,"properties":882,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"46405108-52e0-4772-91b2-0e699481d6b8","2024-11-25T21:17:44.567+00:00",[],"Public-Health-Agency-of-Sweden-Solna-",{"title":883},{"EN":884},"Public Health Agency of Sweden, Solna.",{"openalex":886,"title":888},{"VOID":887},"A5055837146",{"EN":889},"Sven Löfdahl",{"id":891,"sortIndex":62,"researcher":24,"roles":892,"affiliations":893,"properties":905},"b3f12f09-4c5f-4dd2-95eb-7847905dd85a",[],[894],{"id":895,"sortIndex":25,"affiliation":896,"properties":24},"d4f978fd-d224-4b6c-91f0-f31ce6e4e83e",{"id":897,"createTime":898,"updateTime":899,"relativeEntities":900,"slug":901,"properties":902,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"625a325f-a258-45f1-9143-083f852e7b98","2023-12-26T09:52:20.947+00:00","2025-01-24T05:09:44.363+00:00",[],"Department-of-Clinical-Microbiology-County-Hospital-Ryhov-J%C3%B6nk%C3%B6ping-Sweden",{"title":903},{"VI":904},"Department of Clinical Microbiology, County Hospital Ryhov, Jönköping, Sweden",{"openalex":906,"title":908},{"VOID":907},"A5046854270",{"EN":909},"Sture Löfgren",{"id":911,"sortIndex":209,"researcher":24,"roles":912,"affiliations":913,"properties":920},"41dda94e-2876-459b-a5ca-52d7dfea015c",[],[914],{"id":915,"sortIndex":25,"affiliation":916,"properties":24},"6f3ce759-912a-4aaa-96f2-63770acf6583",{"id":897,"createTime":898,"updateTime":899,"relativeEntities":917,"slug":901,"properties":918,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":919},{"VI":904},{"openalex":921,"title":923},{"VOID":922},"A5079986603",{"EN":924},"Anna Jogenfors",{"id":926,"sortIndex":166,"researcher":24,"roles":927,"affiliations":928,"properties":939},"132ce664-ffe6-4a46-9da4-d90fc22bc3ad",[],[929],{"id":930,"sortIndex":25,"affiliation":931,"properties":24},"7e8dcdbb-4ef2-4808-a03a-4919c4f94ff7",{"id":932,"createTime":933,"updateTime":933,"relativeEntities":934,"slug":935,"properties":936,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"3e9a5eda-9d54-43ae-a9bc-d628fadc62a3","2024-11-25T21:17:44.440+00:00",[],"Department-of-Communicable-Disease-Control-County-of-J%C3%B6nk%C3%B6ping-Sweden-",{"title":937},{"EN":938},"Department of Communicable Disease Control, County of Jönköping, Sweden.",{"openalex":940,"title":942},{"VOID":941},"A5037603269",{"EN":943},"Ing-Marie Einemo",{"id":945,"sortIndex":25,"researcher":24,"roles":946,"affiliations":947,"properties":954},"46f48baa-0615-4afb-a53a-6bcfd09894fd",[],[948],{"id":949,"sortIndex":25,"affiliation":950,"properties":24},"d2f1f1d0-18c0-453f-ae2b-6dc9ead4c509",{"id":897,"createTime":898,"updateTime":899,"relativeEntities":951,"slug":901,"properties":952,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":953},{"VI":904},{"openalex":955,"orcid":957,"title":959},{"VOID":956},"A5057055434",{"VOID":958},"https:\u002F\u002Forcid.org\u002F0000-0003-3349-9111",{"EN":960},"Andreas Matussek",{"url":24,"publisher":962,"properties":987},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":963,"slug":10,"properties":964,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":970,"manageAffiliations":971,"indexDatabases":972,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":965,"issn":966,"introduce":967,"eissn":968,"title":969},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[973,980],{"id":76,"indexDatabase":974,"url":91,"indexYears":24,"academicFieldIds":979,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":975,"label":976,"description":977,"key":87,"publicationTags":978,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":981,"url":109,"indexYears":110,"academicFieldIds":986,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":982,"label":983,"description":984,"key":106,"publicationTags":985,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":988,"pages":989,"issue":991},{"VOID":791},{"VOID":990},"147-151",{"VOID":992},"2",19,{"total":993,"publishYear":24,"statisticByYear":995},{"2017":233,"2018":233,"2019":376,"2020":209,"2021":233,"2022":166,"2023":166,"2024":166},"2016-06-01",2016,[999,1002,1005,1008,1012,1015,1018,1021,1024,1028,1031,1034,1037,1040,1043,1046,1049,1052,1055,1058,1061,1064,1067,1070,1073,1076,1079,1082],{"id":24,"text":1000,"url":24,"identifiers":1001},"10.1016\u002FS0140-6736(05)71144-2",{"doi":1000},{"id":24,"text":1003,"url":24,"identifiers":1004},"Remuzzi, 1998, The hemolytic uremic syndrome, Kidney Int Suppl, 66, S54",{},{"id":24,"text":1006,"url":24,"identifiers":1007},"10.1016\u002Fj.ijmm.2005.06.009",{"doi":1006},{"id":24,"text":1009,"url":24,"identifiers":1010},"Griffin, 1991, The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome, Epidemiol Rev, 13, 60, 10.1093\u002Foxfordjournals.epirev.a036079",{"doi":1011},"10.1093\u002Foxfordjournals.epirev.a036079",{"id":24,"text":1013,"url":24,"identifiers":1014},"10.1086\u002F509573",{"doi":1013},{"id":24,"text":1016,"url":24,"identifiers":1017},"10.1007\u002Fs11908-012-0302-4",{"doi":1016},{"id":24,"text":1019,"url":24,"identifiers":1020},"10.1056\u002FNEJMoa1106482",{"doi":1019},{"id":24,"text":1022,"url":24,"identifiers":1023},"10.1056\u002FNEJMoa1106483",{"doi":1022},{"id":24,"text":1025,"url":24,"identifiers":1026},"Boerlin, 1999, Associations between virulence factors of Shiga toxin-producing Escherichia coli and disease in humans, J Clin Microbiol, 37, 497, 10.1128\u002FJCM.37.3.497-503.1999",{"doi":1027},"10.1128\u002FJCM.37.3.497-503.1999",{"id":24,"text":1029,"url":24,"identifiers":1030},"10.1182\u002Fblood-2002-10-3301",{"doi":1029},{"id":24,"text":1032,"url":24,"identifiers":1033},"10.1203\u002F00006450-200108000-00002",{"doi":1032},{"id":24,"text":1035,"url":24,"identifiers":1036},"10.1128\u002FJCM.00860-12",{"doi":1035},{"id":24,"text":1038,"url":24,"identifiers":1039},"10.1128\u002FJCM.01048-14",{"doi":1038},{"id":24,"text":1041,"url":24,"identifiers":1042},"10.1086\u002F338115",{"doi":1041},{"id":24,"text":1044,"url":24,"identifiers":1045},"10.1093\u002Fcid\u002Fcis1218",{"doi":1044},{"id":24,"text":1047,"url":24,"identifiers":1048},"10.1016\u002Fj.idc.2013.05.010",{"doi":1047},{"id":24,"text":1050,"url":24,"identifiers":1051},"10.1128\u002FJCM.41.10.4671-4675.2003",{"doi":1050},{"id":24,"text":1053,"url":24,"identifiers":1054},"10.1128\u002FJCM.02329-12",{"doi":1053},{"id":24,"text":1056,"url":24,"identifiers":1057},"Gould, 2009, Recommendations for diagnosis of shiga toxin–producing Escherichia coli infections by clinical laboratories, MMWR Recomm Rep, 58, 1",{},{"id":24,"text":1059,"url":24,"identifiers":1060},"10.1128\u002FJCM.00991-13",{"doi":1059},{"id":24,"text":1062,"url":24,"identifiers":1063},"10.1128\u002FJCM.39.1.370-374.2001",{"doi":1062},{"id":24,"text":1065,"url":24,"identifiers":1066},"10.1089\u002Ffpd.2007.0065",{"doi":1065},{"id":24,"text":1068,"url":24,"identifiers":1069},"10.1086\u002F313770",{"doi":1068},{"id":24,"text":1071,"url":24,"identifiers":1072},"10.1017\u002FS0950268804003371",{"doi":1071},{"id":24,"text":1074,"url":24,"identifiers":1075},"Available at: http:\u002F\u002Fwww.ecdc.europa.eu\u002Fen\u002Fpublications\u002FPublications\u002Fannual-epidemiological-report-2013.pdf . Accessed 12 October 2014.",{},{"id":24,"text":1077,"url":24,"identifiers":1078},"10.1086\u002F341940",{"doi":1077},{"id":24,"text":1080,"url":24,"identifiers":1081},"10.1016\u002FS0934-8840(11)80342-7",{"doi":1080},{"id":24,"text":1083,"url":24,"identifiers":1084},"10.1001\u002Fjama.2012.264",{"doi":1083},{"id":1086,"createTime":1087,"updateTime":1087,"relativeEntities":1088,"slug":1089,"properties":1090,"entityType":141,"verifyStatus":142,"verifyTime":1087,"verifyNote":143,"syncStatus":23,"languages":1104,"translateLanguages":24,"viewCount":25,"primaryUrl":1105,"fullTextUrl":24,"authors":1106,"publicationType":398,"publisherRelationship":1229,"citationCount":508,"citationInfo":1260,"publishDate":438,"publishYear":439,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1262,"isForceReanalyzing":462},"5870f052-f405-4f12-98af-2068728f8911","2024-08-30T13:20:00.340+00:00",[],"Pediatric-Sporotrichosis-in-Jilin-Province-of-China-2010-2016-a-Retrospective-Study-of-704-Cases",{"mag":1091,"keywords":1093,"openalex":1094,"abstract":1096,"title":1098,"pm":1100,"doi":1102},{"VOID":1092},"2964668976",{},{"VOID":1095},"W2964668976",{"EN":1097},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Background\u003C\u002Fjats:title>\n                  \u003Cjats:p>Pediatric patients make a substantial contribution to the epidemiologic profile of sporotrichosis in Jilin Province, a region of China in which the disease is strongly endemic. However, the exact epidemiologic and clinical manifestations of childhood sporotrichosis in China are unclear.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Methods\u003C\u002Fjats:title>\n                  \u003Cjats:p>The medical records of 704 pediatric patients aged <15 years with sporotrichosis diagnosed by fungus culture at the Department of Dermatology at the First Hospital of Jilin University in a 7-year period (January 2010 to December 2016) were reviewed retrospectively. The patients were from rural areas of Jilin Province, located in northeast China.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Results\u003C\u002Fjats:title>\n                  \u003Cjats:p>Among the 704 pediatric patients, the male\u002Ffemale ratio was 1.41:1, and the highest incidence of sporotrichosis (63%) occurred in those aged 0 to 6 years; 561 patients (80%) contracted sporotrichosis in a colder month. Overall, 655 (93%) patients had lesions in the facial region, whereas 602 (86%) patients had fixed cutaneous sporotrichosis. The incidence of the fixed cutaneous form in the 0- to 6-year age group was significantly higher than that in the 7- to 14-year age group (P = .009). Patients were treated with 10% potassium iodide solution, itraconazole, or terbinafine.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Conclusions\u003C\u002Fjats:title>\n                  \u003Cjats:p>The characteristics of pediatric sporotrichosis in Jilin Provence include the following: (1) a more frequent occurrence in the colder months; (2) the facial region is affected predominantly, in most cases manifesting in the fixed cutaneous form; and (3) significantly more cases occur in younger children than in older ones. Decaying cornstalks used as fire materials might be the source of infection in this population; however, additional research is needed to explore the exact mechanism of infection.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>",{"EN":1099},"Pediatric Sporotrichosis in Jilin Province of China (2010–2016): a Retrospective Study of 704 Cases",{"VOID":1101},"31356658",{"VOID":1103},"10.1093\u002Fjpids\u002Fpiz052",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F9\u002F3\u002F342\u002F5540409",[1107,1129,1144,1161,1178,1195,1212],{"id":1108,"sortIndex":376,"researcher":24,"roles":1109,"affiliations":1110,"properties":1122},"3822c726-724d-4551-9a0c-7961338e922d",[],[1111],{"id":1112,"sortIndex":25,"affiliation":1113,"properties":24},"2db61707-8021-4240-b17a-8bed1ea86d86",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1117,"slug":1118,"properties":1119,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"c20793e7-020a-4202-9e30-c2efc9d13eff","2023-12-29T11:55:15.184+00:00","2024-08-30T13:20:00.351+00:00",[],"Department-of-Dermatology-and-Venerology-First-Hospital-of-Jilin-University-Changchun-Jilin-China",{"title":1120},{"VI":1121},"Department of Dermatology and Venerology, First Hospital of Jilin University, Changchun, Jilin, China",{"openalex":1123,"orcid":1125,"title":1127},{"VOID":1124},"A5035549405",{"VOID":1126},"https:\u002F\u002Forcid.org\u002F0000-0003-2165-2983",{"EN":1128},"Dongyang Zhao",{"id":1130,"sortIndex":62,"researcher":24,"roles":1131,"affiliations":1132,"properties":1139},"9537c9ec-a81d-4a22-816a-6e2d6718b256",[],[1133],{"id":1134,"sortIndex":25,"affiliation":1135,"properties":24},"baef8378-6467-4b0e-912b-12deb0f4391c",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1136,"slug":1118,"properties":1137,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1138},{"VI":1121},{"openalex":1140,"title":1142},{"VOID":1141},"A5102204130",{"EN":1143},"Shuxia Zhong",{"id":1145,"sortIndex":209,"researcher":24,"roles":1146,"affiliations":1147,"properties":1154},"6311c85d-68cb-47bc-8846-c2d09fdc8580",[],[1148],{"id":1149,"sortIndex":25,"affiliation":1150,"properties":24},"3612c206-a04f-4edc-8d8f-fc8acdaa3bf5",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1151,"slug":1118,"properties":1152,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1153},{"VI":1121},{"openalex":1155,"orcid":1157,"title":1159},{"VOID":1156},"A5000269595",{"VOID":1158},"https:\u002F\u002Forcid.org\u002F0000-0002-4267-5036",{"EN":1160},"Yan Cui",{"id":1162,"sortIndex":294,"researcher":24,"roles":1163,"affiliations":1164,"properties":1171},"58c37dc0-1693-45f1-b614-a3818e2339f4",[],[1165],{"id":1166,"sortIndex":25,"affiliation":1167,"properties":24},"47370398-bd9c-4a68-b45a-0c1c30dda72f",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1168,"slug":1118,"properties":1169,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1170},{"VI":1121},{"openalex":1172,"orcid":1174,"title":1176},{"VOID":1173},"A5100371454",{"VOID":1175},"https:\u002F\u002Forcid.org\u002F0000-0001-6823-7774",{"EN":1177},"Shanshan Li",{"id":1179,"sortIndex":233,"researcher":24,"roles":1180,"affiliations":1181,"properties":1188},"20cc21ab-efee-4906-ace1-cf48456e8beb",[],[1182],{"id":1183,"sortIndex":25,"affiliation":1184,"properties":24},"78c511ae-8f3e-45a2-931b-d4cf715dcab3",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1185,"slug":1118,"properties":1186,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1187},{"VI":1121},{"openalex":1189,"orcid":1191,"title":1193},{"VOID":1190},"A5028563266",{"VOID":1192},"https:\u002F\u002Forcid.org\u002F0000-0002-8201-6799",{"EN":1194},"Junfeng Zhou",{"id":1196,"sortIndex":166,"researcher":24,"roles":1197,"affiliations":1198,"properties":1205},"d8dfd80c-acf7-4a5b-99d0-e0234479d6fc",[],[1199],{"id":1200,"sortIndex":25,"affiliation":1201,"properties":24},"ad2a6ee2-c902-4c7c-aeeb-8259e705651c",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1202,"slug":1118,"properties":1203,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1204},{"VI":1121},{"openalex":1206,"orcid":1208,"title":1210},{"VOID":1207},"A5036415591",{"VOID":1209},"https:\u002F\u002Forcid.org\u002F0000-0001-6464-4997",{"EN":1211},"Yang Song",{"id":1213,"sortIndex":25,"researcher":24,"roles":1214,"affiliations":1215,"properties":1222},"3fe646bf-dfb1-43a9-b53c-63555560c0e3",[],[1216],{"id":1217,"sortIndex":25,"affiliation":1218,"properties":24},"f811c3a7-5bfa-466e-9f7c-5f82683a159d",{"id":1114,"createTime":1115,"updateTime":1116,"relativeEntities":1219,"slug":1118,"properties":1220,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1221},{"VI":1121},{"openalex":1223,"orcid":1225,"title":1227},{"VOID":1224},"A5103078374",{"VOID":1226},"https:\u002F\u002Forcid.org\u002F0000-0002-0568-3029",{"EN":1228},"Lei Yao",{"url":24,"publisher":1230,"properties":1255},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1231,"slug":10,"properties":1232,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1238,"manageAffiliations":1239,"indexDatabases":1240,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1233,"issn":1234,"introduce":1235,"eissn":1236,"title":1237},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[1241,1248],{"id":76,"indexDatabase":1242,"url":91,"indexYears":24,"academicFieldIds":1247,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":1243,"label":1244,"description":1245,"key":87,"publicationTags":1246,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":1249,"url":109,"indexYears":110,"academicFieldIds":1254,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":1250,"label":1251,"description":1252,"key":106,"publicationTags":1253,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":1256,"pages":1257,"issue":1259},{"VOID":427},{"VOID":1258},"342-348",{"VOID":431},{"total":508,"publishYear":24,"statisticByYear":1261},{"2020":233,"2021":233,"2022":62,"2023":209,"2024":166},[1263,1266,1270,1274,1278,1282,1286,1290,1294,1298,1302,1306,1310,1314,1318,1322,1326,1330,1334,1338,1341,1345,1348,1352,1356,1360,1364,1368,1372,1376,1380,1383],{"id":24,"text":1264,"url":24,"identifiers":1265},"Schenck, 1898, On refractory subcutaneous abscesses caused by a fungus possibly related to the sporotricha, Bull Johns Hopkins Hosp, 9, 286",{},{"id":24,"text":1267,"url":24,"identifiers":1268},"Morris-Jones, 2002, Sporotrichosis, Clin Exp Dermatol, 27, 427, 10.1046\u002Fj.1365-2230.2002.01087.x",{"doi":1269},"10.1046\u002Fj.1365-2230.2002.01087.x",{"id":24,"text":1271,"url":24,"identifiers":1272},"Bonifaz, 2007, Sporotrichosis in childhood: clinical and therapeutic experience in 25 patients, Pediatr Dermatol, 24, 369, 10.1111\u002Fj.1525-1470.2007.00452.x",{"doi":1273},"10.1111\u002Fj.1525-1470.2007.00452.x",{"id":24,"text":1275,"url":24,"identifiers":1276},"da Rosa, 2005, Epidemiology of sporotrichosis: a study of 304 cases in Brazil, J Am Acad Dermatol, 52, 451, 10.1016\u002Fj.jaad.2004.11.046",{"doi":1277},"10.1016\u002Fj.jaad.2004.11.046",{"id":24,"text":1279,"url":24,"identifiers":1280},"Barros, 2008, An epidemic of sporotrichosis in Rio de Janeiro, Brazil: epidemiological aspects of a series of cases, Epidemiol Infect, 136, 1192, 10.1017\u002FS0950268807009727",{"doi":1281},"10.1017\u002FS0950268807009727",{"id":24,"text":1283,"url":24,"identifiers":1284},"Pappas, 2000, Sporotrichosis in Peru: description of an area of hyperendemicity, Clin Infect Dis, 30, 65, 10.1086\u002F313607",{"doi":1285},"10.1086\u002F313607",{"id":24,"text":1287,"url":24,"identifiers":1288},"Lyon, 2003, Population-based surveillance and a case-control study of risk factors for endemic lymphocutaneous sporotrichosis in Peru, Clin Infect Dis, 36, 34, 10.1086\u002F345437",{"doi":1289},"10.1086\u002F345437",{"id":24,"text":1291,"url":24,"identifiers":1292},"Mata-Essayag, 2013, Epidemiology of sporotrichosis in Venezuela, Int J Dermatol, 52, 974, 10.1111\u002Fj.1365-4632.2012.05849.x",{"doi":1293},"10.1111\u002Fj.1365-4632.2012.05849.x",{"id":24,"text":1295,"url":24,"identifiers":1296},"Song, 2013, Report of 457 sporotrichosis cases from Jilin Province, Northeast China, a serious endemic region, J Eur Acad Dermatol Venereol, 27, 313, 10.1111\u002Fj.1468-3083.2011.04389.x",{"doi":1297},"10.1111\u002Fj.1468-3083.2011.04389.x",{"id":24,"text":1299,"url":24,"identifiers":1300},"Zhang, 2016, Eyelid sporotrichosis: unique clinical findings in 72 patients, Australas J Dermatol, 57, 44, 10.1111\u002Fajd.12286",{"doi":1301},"10.1111\u002Fajd.12286",{"id":24,"text":1303,"url":24,"identifiers":1304},"Verma, 2012, Sporotrichosis in sub-Himalayan India, PLoS Negl Trop Dis, 6, e1673, 10.1371\u002Fjournal.pntd.0001673",{"doi":1305},"10.1371\u002Fjournal.pntd.0001673",{"id":24,"text":1307,"url":24,"identifiers":1308},"Takenaka, 2014, A survey of 165 sporotrichosis cases examined in Nagasaki prefecture from 1951 to 2012, Mycoses, 57, 294, 10.1111\u002Fmyc.12158",{"doi":1309},"10.1111\u002Fmyc.12158",{"id":24,"text":1311,"url":24,"identifiers":1312},"Zhang, 2015, Phylogeography and evolutionary patterns in Sporothrix spanning more than 14 000 human and animal case reports, Persoonia, 35, 1, 10.3767\u002F003158515X687416",{"doi":1313},"10.3767\u002F003158515X687416",{"id":24,"text":1315,"url":24,"identifiers":1316},"Rangel-Gamboa, 2018, A population genetics analysis in clinical isolates of Sporothrix schenckii based on calmodulin and calcium\u002Fcalmodulin-dependent kinase partial gene sequences, Mycoses, 61, 383, 10.1111\u002Fmyc.12751",{"doi":1317},"10.1111\u002Fmyc.12751",{"id":24,"text":1319,"url":24,"identifiers":1320},"Moussa, 2017, Origin and distribution of Sporothrix globosa causing sapronoses in Asia, J Med Microbiol, 66, 560, 10.1099\u002Fjmm.0.000451",{"doi":1321},"10.1099\u002Fjmm.0.000451",{"id":24,"text":1323,"url":24,"identifiers":1324},"Chakrabarti, 2015, Global epidemiology of sporotrichosis, Med Mycol, 53, 3, 10.1093\u002Fmmy\u002Fmyu062",{"doi":1325},"10.1093\u002Fmmy\u002Fmyu062",{"id":24,"text":1327,"url":24,"identifiers":1328},"Barros, 2008, Endemic of zoonotic sporotrichosis: profile of cases in children, Pediatr Infect Dis J, 27, 246, 10.1097\u002FINF.0b013e31815bf309",{"doi":1329},"10.1097\u002FINF.0b013e31815bf309",{"id":24,"text":1331,"url":24,"identifiers":1332},"Mahajan, 2005, Cutaneous sporotrichosis in Himachal Pradesh, India, Mycoses, 48, 25, 10.1111\u002Fj.1439-0507.2004.01058.x",{"doi":1333},"10.1111\u002Fj.1439-0507.2004.01058.x",{"id":24,"text":1335,"url":24,"identifiers":1336},"Kusuhara, 1988, Statistical survey of 150 cases with sporotrichosis, Mycopathologia, 102, 129, 10.1007\u002FBF00437450",{"doi":1337},"10.1007\u002FBF00437450",{"id":24,"text":1339,"url":24,"identifiers":1340},"Song, 1998, The report of 108 cases of pediatric sporotrichosis, Chin J Derm Venereol, 12, 230",{},{"id":24,"text":1342,"url":24,"identifiers":1343},"Ishizaki, 2002, Environmental isolates of Sporothrix schenckii in China, Nihon Ishinkin Gakkai Zasshi, 43, 257, 10.3314\u002Fjjmm.43.257",{"doi":1344},"10.3314\u002Fjjmm.43.257",{"id":24,"text":1346,"url":24,"identifiers":1347},"Li, 2003, Clinical analysis of 62 cases of pediatric sporotrichosis, Clin Pediatr, 21, 676",{},{"id":24,"text":1349,"url":24,"identifiers":1350},"Song, 2011, Infant sporotrichosis in northeast China: a report of 15 cases, Int J Dermatol, 50, 522, 10.1111\u002Fj.1365-4632.2010.04724.x",{"doi":1351},"10.1111\u002Fj.1365-4632.2010.04724.x",{"id":24,"text":1353,"url":24,"identifiers":1354},"Ramírez Soto, 2017, Sporotrichosis among children of a hyperendemic area in Peru: an 8-year retrospective study, Int J Dermatol, 56, 868, 10.1111\u002Fijd.13643",{"doi":1355},"10.1111\u002Fijd.13643",{"id":24,"text":1357,"url":24,"identifiers":1358},"Dooley, 1997, Spook house sporotrichosis. A point-source outbreak of sporotrichosis associated with hay bale props in a Halloween haunted-house, Arch Intern Med, 157, 1885, 10.1001\u002Farchinte.1997.00440370135014",{"doi":1359},"10.1001\u002Farchinte.1997.00440370135014",{"id":24,"text":1361,"url":24,"identifiers":1362},"Conias, 1998, Epidemic cutaneous sporotrichosis: report of 16 cases in Queensland due to mouldy hay, Australas J Dermatol, 39, 34, 10.1111\u002Fj.1440-0960.1998.tb01239.x",{"doi":1363},"10.1111\u002Fj.1440-0960.1998.tb01239.x",{"id":24,"text":1365,"url":24,"identifiers":1366},"Mahajan, 2014, Sporotrichosis: an overview and therapeutic options, Dermatol Res Pract, 2014, 272376, 10.1155\u002F2014\u002F272376",{"doi":1367},"10.1155\u002F2014\u002F272376",{"id":24,"text":1369,"url":24,"identifiers":1370},"Yu, 2013, Phenotypic and molecular identification of Sporothrix isolates of clinical origin in northeast China, Mycopathologia, 176, 67, 10.1007\u002Fs11046-013-9668-6",{"doi":1371},"10.1007\u002Fs11046-013-9668-6",{"id":24,"text":1373,"url":24,"identifiers":1374},"Zhao, 2017, Genetic variation of Sporothrix globosa isolates from diverse geographic and clinical origins in China, Emerg Microbes Infect, 6, e88, 10.1038\u002Femi.2017.75",{"doi":1375},"10.1038\u002Femi.2017.75",{"id":24,"text":1377,"url":24,"identifiers":1378},"Brito, 2007, Comparison of virulence of different Sporothrix schenckii clinical isolates using experimental murine model, Med Mycol, 45, 721, 10.1080\u002F13693780701625131",{"doi":1379},"10.1080\u002F13693780701625131",{"id":24,"text":1381,"url":24,"identifiers":1382},"Li, 2016, Guidelines for the diagnosis and treatment of sporotrichosis, Chin J Traumatol, 49, 456",{},{"id":24,"text":1384,"url":24,"identifiers":1385},"Kauffman, 2007, Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America, Clin Infect Dis, 45, 1255, 10.1086\u002F522765",{"doi":1386},"10.1086\u002F522765",{"id":1388,"createTime":1389,"updateTime":1389,"relativeEntities":1390,"slug":1391,"properties":1392,"entityType":141,"verifyStatus":142,"verifyTime":1389,"verifyNote":143,"syncStatus":23,"languages":1408,"translateLanguages":24,"viewCount":25,"primaryUrl":1409,"fullTextUrl":24,"authors":1410,"publicationType":398,"publisherRelationship":1627,"citationCount":1658,"citationInfo":1659,"publishDate":438,"publishYear":439,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1665,"isForceReanalyzing":462},"4851c3fe-c278-47c6-a682-9d68848516d9","2024-09-05T12:22:28.818+00:00",[],"Multisystem-Inflammatory-Syndrome-in-Children-During-the-Coronavirus-2019-Pandemic-A-Case-Series",{"mag":1393,"keywords":1395,"pmc":1396,"openalex":1398,"abstract":1400,"title":1402,"pm":1404,"doi":1406},{"VOID":1394},"3031583784",{},{"VOID":1397},"7313950",{"VOID":1399},"W3031583784",{"EN":1401},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:p>We present a series of 6 critically ill children with multisystem inflammatory syndrome in children. Key findings of this syndrome include fever, diarrhea, shock, and variable presence of rash, conjunctivitis, extremity edema, and mucous membrane changes.\u003C\u002Fjats:p>",{"EN":1403},"Multisystem Inflammatory Syndrome in Children During the Coronavirus 2019 Pandemic: A Case Series",{"VOID":1405},"32463092",{"VOID":1407},"10.1093\u002Fjpids\u002Fpiaa069",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F9\u002F3\u002F393\u002F5848127",[1411,1443,1476,1499,1520,1537,1560,1587,1604],{"id":1412,"sortIndex":272,"researcher":24,"roles":1413,"affiliations":1414,"properties":1436},"b7f0da63-9609-457c-8073-62ede6e33066",[],[1415,1425],{"id":1416,"sortIndex":25,"affiliation":1417,"properties":24},"69a5c2e0-3fd1-4f90-ab2a-70962f8bac74",{"id":1418,"createTime":1419,"updateTime":1419,"relativeEntities":1420,"slug":1421,"properties":1422,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"f462c342-1d04-4883-a247-1739d8650f80","2024-09-05T12:22:28.833+00:00",[],"Division-of-Critical-Care-Medicine-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":1423},{"EN":1424},"Division of Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"id":1426,"sortIndex":166,"affiliation":1427,"properties":24},"442d1e71-c585-4597-81e9-a62991934eee",{"id":1428,"createTime":1429,"updateTime":1430,"relativeEntities":1431,"slug":1432,"properties":1433,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"239db6af-1bed-45f9-8333-c1c81db5d28e","2024-01-03T11:27:03.026+00:00","2024-12-13T20:57:48.301+00:00",[],"Perelman-School-of-Medicine-University-of-Pennsylvania-Philadelphia-Pennsylvania-USA",{"title":1434},{"VI":1435},"Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA",{"openalex":1437,"orcid":1439,"title":1441},{"VOID":1438},"A5020206810",{"VOID":1440},"https:\u002F\u002Forcid.org\u002F0000-0001-7855-8627",{"EN":1442},"Alexis A. Topjian",{"id":1444,"sortIndex":25,"researcher":24,"roles":1445,"affiliations":1446,"properties":1469},"4f40568c-275d-4a8e-a30a-7f017a886ea0",[],[1447,1457,1463],{"id":1448,"sortIndex":166,"affiliation":1449,"properties":24},"849ebf21-d63d-4675-b91a-4362c9992ec4",{"id":1450,"createTime":1451,"updateTime":1451,"relativeEntities":1452,"slug":1453,"properties":1454,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"ed3fc513-f2d7-4353-90e8-975c865b5732","2024-09-05T12:22:28.839+00:00",[],"Division-of-Infectious-Diseases-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":1455},{"EN":1456},"Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"id":1458,"sortIndex":209,"affiliation":1459,"properties":24},"b9298a05-2bee-4787-bea9-d9bc5647e9f7",{"id":1428,"createTime":1429,"updateTime":1430,"relativeEntities":1460,"slug":1432,"properties":1461,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1462},{"VI":1435},{"id":1464,"sortIndex":25,"affiliation":1465,"properties":24},"b88b3ea1-e760-4e85-9e34-527183c6269f",{"id":1418,"createTime":1419,"updateTime":1419,"relativeEntities":1466,"slug":1421,"properties":1467,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1468},{"EN":1424},{"openalex":1470,"orcid":1472,"title":1474},{"VOID":1471},"A5026668616",{"VOID":1473},"https:\u002F\u002Forcid.org\u002F0000-0002-0204-8708",{"EN":1475},"Kathleen Chiotos",{"id":1477,"sortIndex":150,"researcher":24,"roles":1478,"affiliations":1479,"properties":1492},"34918a12-d75f-418f-a123-3f92b7510029",[],[1480,1486],{"id":1481,"sortIndex":25,"affiliation":1482,"properties":24},"ad668746-7d86-41f4-b001-a19f1064f0b1",{"id":1450,"createTime":1451,"updateTime":1451,"relativeEntities":1483,"slug":1453,"properties":1484,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1485},{"EN":1456},{"id":1487,"sortIndex":166,"affiliation":1488,"properties":24},"e9f7a3b2-2b84-4136-bac9-4ef54b1ec1cc",{"id":1428,"createTime":1429,"updateTime":1430,"relativeEntities":1489,"slug":1432,"properties":1490,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1491},{"VI":1435},{"openalex":1493,"orcid":1495,"title":1497},{"VOID":1494},"A5015172651",{"VOID":1496},"https:\u002F\u002Forcid.org\u002F0000-0001-8395-8537",{"EN":1498},"Audrey R. Odom John",{"id":1500,"sortIndex":376,"researcher":24,"roles":1501,"affiliations":1502,"properties":1513},"7b838177-7466-49b8-af3f-425a6f29e621",[],[1503],{"id":1504,"sortIndex":25,"affiliation":1505,"properties":24},"fd2831e9-520a-42db-a4c6-cb4e15b6872d",{"id":1506,"createTime":1507,"updateTime":1507,"relativeEntities":1508,"slug":1509,"properties":1510,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"ed90da36-5f3d-410a-bab0-806c6ab31f48","2024-09-05T12:22:28.899+00:00",[],"Division-of-Hematology-and-Oncology-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":1511},{"EN":1512},"Division of Hematology and Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"openalex":1514,"orcid":1516,"title":1518},{"VOID":1515},"A5074353491",{"VOID":1517},"https:\u002F\u002Forcid.org\u002F0000-0002-8005-3836",{"EN":1519},"Caroline Diorio",{"id":1521,"sortIndex":233,"researcher":24,"roles":1522,"affiliations":1523,"properties":1530},"8b78a2f6-e77f-41fa-b266-0659b8380ffc",[],[1524],{"id":1525,"sortIndex":25,"affiliation":1526,"properties":24},"6fe3390e-9bee-477a-a53c-76d24f07bba5",{"id":1450,"createTime":1451,"updateTime":1451,"relativeEntities":1527,"slug":1453,"properties":1528,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1529},{"EN":1456},{"openalex":1531,"orcid":1533,"title":1535},{"VOID":1532},"A5054854740",{"VOID":1534},"https:\u002F\u002Forcid.org\u002F0000-0003-2525-1212",{"EN":1536},"Allison M. Blatz",{"id":1538,"sortIndex":166,"researcher":24,"roles":1539,"affiliations":1540,"properties":1553},"ed977e03-ca32-4ffb-9c40-779370e481cc",[],[1541,1547],{"id":1542,"sortIndex":25,"affiliation":1543,"properties":24},"e0b77ebf-e92b-4a7e-ba75-ffb531b8439c",{"id":1450,"createTime":1451,"updateTime":1451,"relativeEntities":1544,"slug":1453,"properties":1545,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1546},{"EN":1456},{"id":1548,"sortIndex":166,"affiliation":1549,"properties":24},"d1af22ba-6558-4758-9966-2e573c9cc3b6",{"id":1428,"createTime":1429,"updateTime":1430,"relativeEntities":1550,"slug":1432,"properties":1551,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1552},{"VI":1435},{"openalex":1554,"orcid":1556,"title":1558},{"VOID":1555},"A5037652877",{"VOID":1557},"https:\u002F\u002Forcid.org\u002F0000-0001-6532-8478",{"EN":1559},"Hamid Bassiri",{"id":1561,"sortIndex":62,"researcher":24,"roles":1562,"affiliations":1563,"properties":1580},"f96b6940-e272-4167-aaa7-d12d9e94a310",[],[1564,1570],{"id":1565,"sortIndex":166,"affiliation":1566,"properties":24},"e9750b8a-f74f-4a0f-94ba-7fabaaa73532",{"id":1428,"createTime":1429,"updateTime":1430,"relativeEntities":1567,"slug":1432,"properties":1568,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1569},{"VI":1435},{"id":1571,"sortIndex":25,"affiliation":1572,"properties":24},"66ca1e0f-2c53-41e0-9b25-a286e29dc86b",{"id":1573,"createTime":1574,"updateTime":1574,"relativeEntities":1575,"slug":1576,"properties":1577,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"d78f796f-cf1b-43d6-a374-62ba078cead2","2024-09-05T12:22:28.867+00:00",[],"Division-of-Rheumatology-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":1578},{"EN":1579},"Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"openalex":1581,"orcid":1583,"title":1585},{"VOID":1582},"A5077136052",{"VOID":1584},"https:\u002F\u002Forcid.org\u002F0000-0002-1691-4814",{"EN":1586},"Joyce C. Chang",{"id":1588,"sortIndex":209,"researcher":24,"roles":1589,"affiliations":1590,"properties":1597},"f2ca7c93-7d15-43d3-9959-02306fa6309b",[],[1591],{"id":1592,"sortIndex":25,"affiliation":1593,"properties":24},"9d6971c5-bf55-4ece-958d-e61aad24e7b4",{"id":1573,"createTime":1574,"updateTime":1574,"relativeEntities":1594,"slug":1576,"properties":1595,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1596},{"EN":1579},{"openalex":1598,"orcid":1600,"title":1602},{"VOID":1599},"A5067266858",{"VOID":1601},"https:\u002F\u002Forcid.org\u002F0000-0002-4603-7963",{"EN":1603},"Edward M. Behrens",{"id":1605,"sortIndex":294,"researcher":24,"roles":1606,"affiliations":1607,"properties":1620},"a2147667-d4ca-41fb-96bc-e2505ba87670",[],[1608,1614],{"id":1609,"sortIndex":25,"affiliation":1610,"properties":24},"578e765c-7c87-4d94-803d-c64fc2779f25",{"id":1418,"createTime":1419,"updateTime":1419,"relativeEntities":1611,"slug":1421,"properties":1612,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1613},{"EN":1424},{"id":1615,"sortIndex":166,"affiliation":1616,"properties":24},"05d8a0b6-4ba4-40e3-98aa-3284cd622b30",{"id":1428,"createTime":1429,"updateTime":1430,"relativeEntities":1617,"slug":1432,"properties":1618,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1619},{"VI":1435},{"openalex":1621,"orcid":1623,"title":1625},{"VOID":1622},"A5088663182",{"VOID":1624},"https:\u002F\u002Forcid.org\u002F0000-0001-9936-9569",{"EN":1626},"Julie C. Fitzgerald",{"url":24,"publisher":1628,"properties":1653},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1629,"slug":10,"properties":1630,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1636,"manageAffiliations":1637,"indexDatabases":1638,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1631,"issn":1632,"introduce":1633,"eissn":1634,"title":1635},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[1639,1646],{"id":76,"indexDatabase":1640,"url":91,"indexYears":24,"academicFieldIds":1645,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":1641,"label":1642,"description":1643,"key":87,"publicationTags":1644,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":1647,"url":109,"indexYears":110,"academicFieldIds":1652,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":1648,"label":1649,"description":1650,"key":106,"publicationTags":1651,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":1654,"pages":1655,"issue":1657},{"VOID":427},{"VOID":1656},"393-398",{"VOID":431},352,{"total":1658,"publishYear":24,"statisticByYear":1660},{"2018":166,"2020":1661,"2021":1662,"2022":1663,"2023":1664,"2024":706},94,141,62,28,[1666,1668,1671,1674,1678,1681,1684,1688,1692],{"id":24,"text":810,"url":24,"identifiers":1667},{"doi":812},{"id":24,"text":1669,"url":24,"identifiers":1670},"New York City Health Department",{},{"id":24,"text":1672,"url":24,"identifiers":1673},"Centers for Disease Control and Prevention",{},{"id":24,"text":1675,"url":24,"identifiers":1676},"Dong, 2020, Epidemiology of COVID-19 among children in China, Pediatrics, 10.1542\u002Fpeds.2020-0702",{"doi":1677},"10.1542\u002Fpeds.2020-0702",{"id":24,"text":1679,"url":24,"identifiers":1680},"2020, Coronavirus disease 2019 in children, Morbid Mortal Wkly Rep, 69, 422",{},{"id":24,"text":1682,"url":24,"identifiers":1683},"Jones",{},{"id":24,"text":1685,"url":24,"identifiers":1686},"Yun, 2011, Associated symptoms of Kawasaki disease, Korean Circ J, 41, 394, 10.4070\u002Fkcj.2011.41.7.394",{"doi":1687},"10.4070\u002Fkcj.2011.41.7.394",{"id":24,"text":1689,"url":24,"identifiers":1690},"Baker, 2009, Associated symptoms in the ten days before diagnosis of Kawasaki disease, J Pediatr, 154, 592, 10.1016\u002Fj.jpeds.2008.10.006",{"doi":1691},"10.1016\u002Fj.jpeds.2008.10.006",{"id":24,"text":1693,"url":24,"identifiers":1694},"Schuster, 2017, Hyponatremia is a feature of Kawasaki disease shock syndrome: a case-control study, J Pediatric Infect Dis Soc, 6, 386, 10.1093\u002Fjpids\u002Fpiw081",{"doi":1695},"10.1093\u002Fjpids\u002Fpiw081",{"id":1697,"createTime":1698,"updateTime":1698,"relativeEntities":1699,"slug":1700,"properties":1701,"entityType":141,"verifyStatus":142,"verifyTime":1698,"verifyNote":143,"syncStatus":23,"languages":1717,"translateLanguages":24,"viewCount":25,"primaryUrl":1718,"fullTextUrl":24,"authors":1719,"publicationType":398,"publisherRelationship":1864,"citationCount":1896,"citationInfo":1897,"publishDate":1899,"publishYear":439,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":1900,"isForceReanalyzing":462},"29540829-d1a4-4bc1-a462-f1402d9fa13f","2024-09-05T12:21:46.040+00:00",[],"Guillain-Barr%C3%A9-Syndrome-Associated-With-Severe-Acute-Respiratory-Syndrome-Coronavirus-2-Detection-and-Coronavirus-Disease-2019-in-a-Child",{"mag":1702,"keywords":1704,"pmc":1705,"openalex":1707,"abstract":1709,"title":1711,"pm":1713,"doi":1715},{"VOID":1703},"3042041520",{},{"VOID":1706},"7454732",{"VOID":1708},"W3042041520",{"EN":1710},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:p>Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what is believed to be the first adult case of a SARS-CoV-2 infection associated with acute Guillain-Barré syndrome (GBS), followed by 5 adult Italian patients and another case in the United States. In the current report, we present one of the first descriptions of an association of GBS and SARS-CoV-2 infection in a child. In our facility, an 11-year-old boy presented with typical features of GBS and, after 5 days, a morbilliform skin rash over the palms of both hands. Three weeks before the start of the neurological symptoms, the boy had experienced an episode of mild febrile illness with mild respiratory manifestations and a persistent cough. The diagnosis of SARS-CoV-2 infection was confirmed by oropharyngeal swab on reverse-transcription polymerase chain reaction assay. The disease course of our patient strongly suggests a possible relationship between the development of GBS and SARS-CoV-2 infection. The case is discussed in view of previous case reports regarding the association of GBS and COVID-19.\u003C\u002Fjats:p>",{"EN":1712},"Guillain-Barré Syndrome Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Detection and Coronavirus Disease 2019 in a Child",{"VOID":1714},"32652520",{"VOID":1716},"10.1093\u002Fjpids\u002Fpiaa086",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F9\u002F4\u002F510\u002F5870366",[1720,1742,1761,1778,1799,1821,1842],{"id":1721,"sortIndex":233,"researcher":24,"roles":1722,"affiliations":1723,"properties":1735},"c300b0f5-d884-432b-a9bd-7e3e99d58623",[],[1724],{"id":1725,"sortIndex":25,"affiliation":1726,"properties":24},"b229a29b-d12c-461e-97c3-d6cd481e07be",{"id":1727,"createTime":1728,"updateTime":1729,"relativeEntities":1730,"slug":1731,"properties":1732,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"2c340221-bf4d-46a9-83e5-17fe3d3cf067","2024-02-09T11:00:21.046+00:00","2024-09-05T12:21:46.091+00:00",[],"Internal-Medicine-Department-Faculty-of-Medicine-Cairo-University-Cairo-Egypt",{"title":1733},{"VI":1734},"Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt",{"openalex":1736,"orcid":1738,"title":1740},{"VOID":1737},"A5101543297",{"VOID":1739},"https:\u002F\u002Forcid.org\u002F0000-0003-0445-2277",{"EN":1741},"Ahmed Saad",{"id":1743,"sortIndex":166,"researcher":24,"roles":1744,"affiliations":1745,"properties":1756},"4cadb183-cd2b-40e3-b5b5-8c4b04b4672b",[],[1746],{"id":1747,"sortIndex":25,"affiliation":1748,"properties":24},"1355a54a-adc4-4ad8-bcd2-c782ca18fe95",{"id":1749,"createTime":1750,"updateTime":1750,"relativeEntities":1751,"slug":1752,"properties":1753,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"21922d40-47eb-4673-9352-c1d180a11c98","2024-09-05T12:21:46.055+00:00",[],"Pediatric-Neurology-Department-Dr-Erfan-and-Bagedo-General-Hospital-Jeddah-Kingdom-of-Saudi-Arabia",{"title":1754},{"EN":1755},"Pediatric Neurology Department, Dr Erfan and Bagedo General Hospital, Jeddah, Kingdom of Saudi Arabia",{"openalex":1757,"title":1759},{"VOID":1758},"A5020171704",{"EN":1760},"Fairouz Zakaria",{"id":1762,"sortIndex":25,"researcher":24,"roles":1763,"affiliations":1764,"properties":1771},"0dc26bab-d7a8-40ce-9fed-51e9b023ce09",[],[1765],{"id":1766,"sortIndex":25,"affiliation":1767,"properties":24},"807e7da8-f1fd-4ce3-b9de-75009857074a",{"id":1749,"createTime":1750,"updateTime":1750,"relativeEntities":1768,"slug":1752,"properties":1769,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":1770},{"EN":1755},{"openalex":1772,"orcid":1774,"title":1776},{"VOID":1773},"A5035446676",{"VOID":1775},"https:\u002F\u002Forcid.org\u002F0000-0003-3968-8327",{"EN":1777},"Maher Ben Khalifa",{"id":1779,"sortIndex":294,"researcher":24,"roles":1780,"affiliations":1781,"properties":1792},"4f525865-dd36-480d-ae72-86ef4bb3adf3",[],[1782],{"id":1783,"sortIndex":25,"affiliation":1784,"properties":24},"8ce32940-41ff-4c4a-95b6-8e2ca66e748f",{"id":1785,"createTime":1786,"updateTime":1786,"relativeEntities":1787,"slug":1788,"properties":1789,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"123795da-df6f-4894-b45d-03b7dcd236f2","2024-09-05T12:21:46.131+00:00",[],"Faculty-of-Behavioral-Management-and-Social-Sciences-Department-of-Psychology-Health-and-Technology-University-of-Twente-Enschede-The-Netherlands",{"title":1790},{"EN":1791},"Faculty of Behavioral, Management and Social Sciences, Department of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands",{"openalex":1793,"orcid":1795,"title":1797},{"VOID":1794},"A5080191865",{"VOID":1796},"https:\u002F\u002Forcid.org\u002F0000-0003-0399-2669",{"EN":1798},"Johannes J. Rasker",{"id":1800,"sortIndex":209,"researcher":24,"roles":1801,"affiliations":1802,"properties":1814},"dbfafa65-d1b6-4984-9557-77dd0cfb099b",[],[1803],{"id":1804,"sortIndex":25,"affiliation":1805,"properties":24},"835ce116-8c66-4e3a-a1bd-4aab996c4d5a",{"id":1806,"createTime":1807,"updateTime":1808,"relativeEntities":1809,"slug":1810,"properties":1811,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"5064c681-32f5-4393-aebb-85a4b3a597d0","2023-12-06T17:09:39.621+00:00","2024-09-05T12:21:46.079+00:00",[],"Radiology-Department-Faculty-of-Medicine-Cairo-University-Cairo-Egypt",{"title":1812},{"VI":1813},"Radiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt",{"openalex":1815,"orcid":1817,"title":1819},{"VOID":1816},"A5049118245",{"VOID":1818},"https:\u002F\u002Forcid.org\u002F0000-0002-0423-2285",{"EN":1820},"Yasser Ragab",{"id":1822,"sortIndex":62,"researcher":24,"roles":1823,"affiliations":1824,"properties":1835},"b005f7b3-e9a6-456a-91f9-ce995117a167",[],[1825],{"id":1826,"sortIndex":25,"affiliation":1827,"properties":24},"3afe54c0-cd9e-4fcc-ada8-67243fab1999",{"id":1828,"createTime":1829,"updateTime":1829,"relativeEntities":1830,"slug":1831,"properties":1832,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"cc7598ab-b0ea-4dc4-9d72-efb8361e0626","2024-09-05T12:21:46.104+00:00",[],"Pediatric-Department-Faculty-of-Medicine-King-Abdul-Aziz-University-Jeddah-Saudi-Arabia",{"title":1833},{"EN":1834},"Pediatric Department, Faculty of Medicine, King Abdul-Aziz University, Jeddah, Saudi Arabia",{"openalex":1836,"orcid":1838,"title":1840},{"VOID":1837},"A5087221112",{"VOID":1839},"https:\u002F\u002Forcid.org\u002F0000-0002-0115-9457",{"EN":1841},"Ahmed K. Bamaga",{"id":1843,"sortIndex":376,"researcher":24,"roles":1844,"affiliations":1845,"properties":1857},"5bb46e87-7b87-44d4-84db-e0135f77ef95",[],[1846],{"id":1847,"sortIndex":25,"affiliation":1848,"properties":24},"e3982a65-b75f-4975-a749-4d0e1c0e6334",{"id":1849,"createTime":1850,"updateTime":1851,"relativeEntities":1852,"slug":1853,"properties":1854,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"0a5b178e-2410-4523-80db-f1b7f4a12701","2024-02-22T23:11:08.781+00:00","2025-06-11T23:16:09.330+00:00",[],"Rheumatology-and-Rehabilitation-Department-Faculty-of-Medicine-Cairo-University-Cairo-Egypt",{"title":1855},{"VI":1856},"Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo University, Cairo, Egypt",{"openalex":1858,"orcid":1860,"title":1862},{"VOID":1859},"A5024318295",{"VOID":1861},"https:\u002F\u002Forcid.org\u002F0000-0003-2050-3847",{"EN":1863},"Yasser Emad",{"url":24,"publisher":1865,"properties":1890},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1866,"slug":10,"properties":1867,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1873,"manageAffiliations":1874,"indexDatabases":1875,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1868,"issn":1869,"introduce":1870,"eissn":1871,"title":1872},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[1876,1883],{"id":76,"indexDatabase":1877,"url":91,"indexYears":24,"academicFieldIds":1882,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":1878,"label":1879,"description":1880,"key":87,"publicationTags":1881,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":1884,"url":109,"indexYears":110,"academicFieldIds":1889,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":1885,"label":1886,"description":1887,"key":106,"publicationTags":1888,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":1891,"pages":1892,"issue":1894},{"VOID":427},{"VOID":1893},"510-513",{"VOID":1895},"4",91,{"total":1896,"publishYear":24,"statisticByYear":1898},{"2020":185,"2021":435,"2022":1664,"2023":508,"2024":376},"2020-09-17",[1901,1905,1909,1913,1917,1921,1925,1928],{"id":24,"text":1902,"url":24,"identifiers":1903},"Li, 2020, The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients, J Med Virol, 92, 552, 10.1002\u002Fjmv.25728",{"doi":1904},"10.1002\u002Fjmv.25728",{"id":24,"text":1906,"url":24,"identifiers":1907},"Mannheim, 2020, Characteristics of hospitalized pediatric COVID-19 cases—Chicago, Illinois, March–April 2020 [manuscript published online ahead of print 1 June 2020], J Pediatric Infect Dis Soc, 10.1093\u002Fjpids\u002Fpiaa070",{"doi":1908},"10.1093\u002Fjpids\u002Fpiaa070",{"id":24,"text":1910,"url":24,"identifiers":1911},"Zhao, 2020, Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence?, Lancet Neurol, 19, 383, 10.1016\u002FS1474-4422(20)30109-5",{"doi":1912},"10.1016\u002FS1474-4422(20)30109-5",{"id":24,"text":1914,"url":24,"identifiers":1915},"Toscano, 2020, Guillain-Barré syndrome associated with SARS-CoV-2, N Engl J Med, 382, 2574, 10.1056\u002FNEJMc2009191",{"doi":1916},"10.1056\u002FNEJMc2009191",{"id":24,"text":1918,"url":24,"identifiers":1919},"Virani, 2020, Guillain-Barré syndrome associated with SARS-CoV-2 infection, IDCases, 20, e00771, 10.1016\u002Fj.idcr.2020.e00771",{"doi":1920},"10.1016\u002Fj.idcr.2020.e00771",{"id":24,"text":1922,"url":24,"identifiers":1923},"Shahrizaila, 2011, Guillain-barré syndrome animal model: the first proof of molecular mimicry in human autoimmune disorder, J Biomed Biotechnol, 2011, 829129, 10.1155\u002F2011\u002F829129",{"doi":1924},"10.1155\u002F2011\u002F829129",{"id":24,"text":1926,"url":24,"identifiers":1927},"Coffey",{},{"id":24,"text":1929,"url":24,"identifiers":1930},"Galván Casas, 2020, Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases, Br J Dermatol, 183, 71, 10.1111\u002Fbjd.19163",{"doi":1931},"10.1111\u002Fbjd.19163",{"id":1933,"createTime":1934,"updateTime":1934,"relativeEntities":1935,"slug":1936,"properties":1937,"entityType":141,"verifyStatus":142,"verifyTime":1934,"verifyNote":143,"syncStatus":23,"languages":1952,"translateLanguages":24,"viewCount":25,"primaryUrl":1953,"fullTextUrl":24,"authors":1954,"publicationType":398,"publisherRelationship":2068,"citationCount":2101,"citationInfo":2102,"publishDate":2105,"publishYear":2106,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":2107,"isForceReanalyzing":462},"b3f61f42-4131-46c2-af1c-385328bae38a","2024-11-28T07:13:20.062+00:00",[],"Noninfectious-Manifestations-and-Complications-of-Chronic-Granulomatous-Disease",{"mag":1938,"keywords":1940,"pmc":1941,"openalex":1943,"abstract":1945,"title":1946,"pm":1948,"doi":1950},{"VOID":1939},"2802560068",{},{"VOID":1942},"5946858",{"VOID":1944},"W2802560068",{},{"EN":1947},"Noninfectious Manifestations and Complications of Chronic Granulomatous Disease",{"VOID":1949},"29746679",{"VOID":1951},"10.1093\u002Fjpids\u002Fpiy014",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F7\u002Fsuppl_1\u002FS18\u002F4994084",[1955,1974,1994,2015,2047],{"id":1956,"sortIndex":209,"researcher":24,"roles":1957,"affiliations":1958,"properties":1969},"8eed2450-9863-4fb0-b303-0cd16412b47d",[],[1959],{"id":1960,"sortIndex":25,"affiliation":1961,"properties":24},"b01ee890-94f1-4dac-bf74-50294f7f48d7",{"id":1962,"createTime":1963,"updateTime":1963,"relativeEntities":1964,"slug":1965,"properties":1966,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"ca369296-77fe-4f20-b9e4-a741d74ce469","2024-11-28T07:13:20.106+00:00",[],"Division-of-Gastroenterology-Department-of-Pediatrics-Vanderbilt-University-School-of-Medicine-Nashville-Tennessee",{"title":1967},{"EN":1968},"Division of Gastroenterology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee",{"openalex":1970,"title":1972},{"VOID":1971},"A5086666170",{"EN":1973},"Kelly Thomsen",{"id":1975,"sortIndex":233,"researcher":24,"roles":1976,"affiliations":1977,"properties":1989},"851f22f1-4541-4edc-9cf8-7cc3cdb7b442",[],[1978],{"id":1979,"sortIndex":25,"affiliation":1980,"properties":24},"8090bc1b-60e6-42d5-9bba-f89d0f28bc71",{"id":1981,"createTime":1982,"updateTime":1983,"relativeEntities":1984,"slug":1985,"properties":1986,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"dd00b581-7093-4d51-ba70-5972a5370b8b","2024-02-06T01:03:15.683+00:00","2024-11-28T07:13:20.118+00:00",[],"National-Human-Genome-Research-Institute-National-Institutes-of-Health-Bethesda-Maryland-",{"title":1987},{"VI":1988},"National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland;",{"openalex":1990,"title":1992},{"VOID":1991},"A5084179048",{"EN":1993},"Elizabeth Garabedian",{"id":1995,"sortIndex":25,"researcher":24,"roles":1996,"affiliations":1997,"properties":2008},"ed65dd33-cd48-4779-abb7-21d601c259c2",[],[1998],{"id":1999,"sortIndex":25,"affiliation":2000,"properties":24},"4513e23a-ec94-406a-a248-164be0cf78b7",{"id":2001,"createTime":2002,"updateTime":2002,"relativeEntities":2003,"slug":2004,"properties":2005,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"bd8b3bb7-3c49-47ad-86f0-39a377b27496","2024-11-28T07:13:20.078+00:00",[],"Division-of-Allergy-and-Immunology-Department-of-Pediatrics-Children-s-Hospital-of-Philadelphia-Pennsylvania",{"title":2006},{"EN":2007},"Division of Allergy and Immunology, Department of Pediatrics, Children’s Hospital of Philadelphia, Pennsylvania",{"openalex":2009,"orcid":2011,"title":2013},{"VOID":2010},"A5020579810",{"VOID":2012},"https:\u002F\u002Forcid.org\u002F0000-0001-5569-4132",{"EN":2014},"Sarah E. Henrickson",{"id":2016,"sortIndex":166,"researcher":24,"roles":2017,"affiliations":2018,"properties":2040},"aef75056-bfd7-42c9-9471-5cff885c0dd5",[],[2019,2030],{"id":2020,"sortIndex":25,"affiliation":2021,"properties":24},"e9db395a-7ff9-4323-9ccb-f66113e66ca0",{"id":2022,"createTime":2023,"updateTime":2024,"relativeEntities":2025,"slug":2026,"properties":2027,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"08f99944-b0f0-431b-9aa8-34a29a4ef823","2024-11-28T07:13:20.091+00:00","2025-06-11T21:56:38.647+00:00",[],"Departments-of-Medicine-and-Pediatrics-Donald-and-Barbara-Zucker-School-of-Medicine-at-Hofstra-Northwell-Great-Neck-New-York",{"title":2028},{"EN":2029},"Departments of Medicine and Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra\u002FNorthwell, Great Neck, New York",{"id":2031,"sortIndex":166,"affiliation":2032,"properties":24},"21cf5d20-22c4-4e49-ba3f-83d0e02d4d22",{"id":2033,"createTime":2034,"updateTime":2034,"relativeEntities":2035,"slug":2036,"properties":2037,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"0e5d84b7-0279-48a4-b5d8-4ba0eda21912","2024-11-28T07:13:20.094+00:00",[],"Institute-for-Immunology-University-of-Pennsylvania-Philadelphia",{"title":2038},{"EN":2039},"Institute for Immunology, University of Pennsylvania, Philadelphia",{"openalex":2041,"orcid":2043,"title":2045},{"VOID":2042},"A5002564042",{"VOID":2044},"https:\u002F\u002Forcid.org\u002F0000-0002-3346-7243",{"EN":2046},"Artemio M. Jongco",{"id":2048,"sortIndex":62,"researcher":24,"roles":2049,"affiliations":2050,"properties":2061},"2c33d66a-4430-484e-9d53-3d268c8a78bd",[],[2051],{"id":2052,"sortIndex":25,"affiliation":2053,"properties":24},"0c513849-873d-4d2e-a28b-8c6bc097b635",{"id":2054,"createTime":2055,"updateTime":2055,"relativeEntities":2056,"slug":2057,"properties":2058,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"bf970698-4f95-4a56-8800-891979c31c9b","2024-11-28T07:13:20.131+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Vanderbilt-University-School-of-Medicine-Nashville-Tennessee",{"title":2059},{"EN":2060},"Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee",{"openalex":2062,"orcid":2064,"title":2066},{"VOID":2063},"A5073936493",{"VOID":2065},"https:\u002F\u002Forcid.org\u002F0000-0001-9240-0164",{"EN":2067},"Isaac Thomsen",{"url":24,"publisher":2069,"properties":2094},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":2070,"slug":10,"properties":2071,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":2077,"manageAffiliations":2078,"indexDatabases":2079,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":2072,"issn":2073,"introduce":2074,"eissn":2075,"title":2076},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[2080,2087],{"id":76,"indexDatabase":2081,"url":91,"indexYears":24,"academicFieldIds":2086,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":2082,"label":2083,"description":2084,"key":87,"publicationTags":2085,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":2088,"url":109,"indexYears":110,"academicFieldIds":2093,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":2089,"label":2090,"description":2091,"key":106,"publicationTags":2092,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":2095,"pages":2097,"issue":2099},{"VOID":2096},"7",{"VOID":2098},"S18-S24",{"VOID":2100},"suppl_1",63,{"total":2101,"publishYear":24,"statisticByYear":2103},{"2019":185,"2020":2104,"2021":581,"2022":62,"2023":185,"2024":185},18,"2018-05-09",2018,[2108,2112,2116,2120,2124,2128,2132,2136,2140,2144,2148,2151,2155,2159,2163,2167,2171,2175,2179,2183,2187,2191,2195,2199,2203,2207,2211,2214,2218,2222,2226,2230,2234,2238,2242,2246,2250,2254,2258,2262,2266,2269,2273,2277,2281,2285,2289,2293,2297,2301,2305,2309,2313,2317,2321,2325,2329,2333,2337,2341,2345,2348,2352,2356,2360,2364,2368,2372,2376,2380,2384,2388,2392,2396,2400,2404,2408,2412,2416],{"id":24,"text":2109,"url":24,"identifiers":2110},"Etzioni, 2003, Immune deficiency and autoimmunity, Autoimmun Rev, 2, 364, 10.1016\u002FS1568-9972(03)00052-1",{"doi":2111},"10.1016\u002FS1568-9972(03)00052-1",{"id":24,"text":2113,"url":24,"identifiers":2114},"De Ravin, 2008, Chronic granulomatous disease as a risk factor for autoimmune disease, J Allergy Clin Immunol, 122, 1097, 10.1016\u002Fj.jaci.2008.07.050",{"doi":2115},"10.1016\u002Fj.jaci.2008.07.050",{"id":24,"text":2117,"url":24,"identifiers":2118},"Schäppi, 2001, Colitis in chronic granulomatous disease, Arch Dis Child, 84, 147, 10.1136\u002Fadc.84.2.147",{"doi":2119},"10.1136\u002Fadc.84.2.147",{"id":24,"text":2121,"url":24,"identifiers":2122},"Marciano, 2004, Gastrointestinal involvement in chronic granulomatous disease, Pediatrics, 114, 462, 10.1542\u002Fpeds.114.2.462",{"doi":2123},"10.1542\u002Fpeds.114.2.462",{"id":24,"text":2125,"url":24,"identifiers":2126},"Alimchandani, 2013, Gastrointestinal histopathology in chronic granulomatous disease: a study of 87 patients, Am J Surg Pathol, 37, 1365, 10.1097\u002FPAS.0b013e318297427d",{"doi":2127},"10.1097\u002FPAS.0b013e318297427d",{"id":24,"text":2129,"url":24,"identifiers":2130},"Kang, 2009, Advances in treatment for chronic granulomatous disease, Immunol Res, 43, 77, 10.1007\u002Fs12026-008-8051-z",{"doi":2131},"10.1007\u002Fs12026-008-8051-z",{"id":24,"text":2133,"url":24,"identifiers":2134},"Winkelstein, 2000, Chronic granulomatous disease. Report on a national registry of 368 patients, Medicine (Baltimore), 79, 155, 10.1097\u002F00005792-200005000-00003",{"doi":2135},"10.1097\u002F00005792-200005000-00003",{"id":24,"text":2137,"url":24,"identifiers":2138},"Khangura, 2016, Gastrointestinal features of chronic granulomatous disease found during endoscopy, Clin Gastroenterol Hepatol, 14, 395, 10.1016\u002Fj.cgh.2015.10.030",{"doi":2139},"10.1016\u002Fj.cgh.2015.10.030",{"id":24,"text":2141,"url":24,"identifiers":2142},"Liu, 2009, CD68 expression is markedly different in Crohn’s disease and the colitis associated with chronic granulomatous disease, Inflamm Bowel Dis, 15, 1213, 10.1002\u002Fibd.20890",{"doi":2143},"10.1002\u002Fibd.20890",{"id":24,"text":2145,"url":24,"identifiers":2146},"Uzel, 2010, Complications of tumor necrosis factor-α blockade in chronic granulomatous disease-related colitis, Clin Infect Dis, 51, 1429, 10.1086\u002F657308",{"doi":2147},"10.1086\u002F657308",{"id":24,"text":2149,"url":24,"identifiers":2150},"Vinh, Mucormycosis in chronic granulomatous disease: association with iatrogenic immunosuppression. J Allergy Clin Immunol 2009;123:1411-3",{},{"id":24,"text":2152,"url":24,"identifiers":2153},"Seger, 2010, Hematopoietic stem cell transplantation for chronic granulomatous disease, Immunol Allergy Clin North Am, 30, 195, 10.1016\u002Fj.iac.2010.01.003",{"doi":2154},"10.1016\u002Fj.iac.2010.01.003",{"id":24,"text":2156,"url":24,"identifiers":2157},"Martire, 2008, Clinical features, long-term follow-up and outcome of a large cohort of patients with chronic granulomatous disease: an Italian multicenter study, Clin Immunol, 126, 155, 10.1016\u002Fj.clim.2007.09.008",{"doi":2158},"10.1016\u002Fj.clim.2007.09.008",{"id":24,"text":2160,"url":24,"identifiers":2161},"Jones, 2008, Special article: chronic granulomatous disease in the United Kingdom and Ireland: a comprehensive national patient-based registry, Clin Exp Immunol, 152, 211, 10.1111\u002Fj.1365-2249.2008.03644.x",{"doi":2162},"10.1111\u002Fj.1365-2249.2008.03644.x",{"id":24,"text":2164,"url":24,"identifiers":2165},"van den Berg, 2009, Chronic granulomatous disease: the European experience, PLoS One, 4, e5234, 10.1371\u002Fjournal.pone.0005234",{"doi":2166},"10.1371\u002Fjournal.pone.0005234",{"id":24,"text":2168,"url":24,"identifiers":2169},"Mahdaviani, 2013, Pulmonary manifestations of chronic granulomatous disease, Expert Rev Clin Immunol, 9, 153, 10.1586\u002Feci.12.98",{"doi":2170},"10.1586\u002Feci.12.98",{"id":24,"text":2172,"url":24,"identifiers":2173},"Salvator, 2015, Pulmonary manifestations in adult patients with chronic granulomatous disease, Eur Respir J, 45, 1613, 10.1183\u002F09031936.00118414",{"doi":2174},"10.1183\u002F09031936.00118414",{"id":24,"text":2176,"url":24,"identifiers":2177},"Rosenzweig, 2008, Inflammatory manifestations in chronic granulomatous disease (CGD), J Clin Immunol, 28, S67, 10.1007\u002Fs10875-007-9160-5",{"doi":2178},"10.1007\u002Fs10875-007-9160-5",{"id":24,"text":2180,"url":24,"identifiers":2181},"Meissner, 2010, Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease, Blood, 116, 1570, 10.1182\u002Fblood-2010-01-264218",{"doi":2182},"10.1182\u002Fblood-2010-01-264218",{"id":24,"text":2184,"url":24,"identifiers":2185},"Liese, 2000, Long-term follow-up and outcome of 39 patients with chronic granulomatous disease, J Pediatr, 137, 687, 10.1067\u002Fmpd.2000.109112",{"doi":2186},"10.1067\u002Fmpd.2000.109112",{"id":24,"text":2188,"url":24,"identifiers":2189},"Siddiqui, 2007, Fulminant mulch pneumonitis: an emergency presentation of chronic granulomatous disease, Clin Infect Dis, 45, 673, 10.1086\u002F520985",{"doi":2190},"10.1086\u002F520985",{"id":24,"text":2192,"url":24,"identifiers":2193},"Magnani, 2014, Inflammatory manifestations in a single-center cohort of patients with chronic granulomatous disease, J Allergy Clin Immunol, 134, 655, 10.1016\u002Fj.jaci.2014.04.014",{"doi":2194},"10.1016\u002Fj.jaci.2014.04.014",{"id":24,"text":2196,"url":24,"identifiers":2197},"Kuijpers, 2012, Inflammation and repeated infections in CGD: two sides of a coin, Cell Mol Life Sci, 69, 7, 10.1007\u002Fs00018-011-0834-z",{"doi":2198},"10.1007\u002Fs00018-011-0834-z",{"id":24,"text":2200,"url":24,"identifiers":2201},"Godoy, 2008, Chest radiographic and CT manifestations of chronic granulomatous disease in adults, AJR Am J Roentgenol, 191, 1570, 10.2214\u002FAJR.07.3482",{"doi":2202},"10.2214\u002FAJR.07.3482",{"id":24,"text":2204,"url":24,"identifiers":2205},"Towbin, 2010, Chronic granulomatous disease, Pediatr Radiol, 40, 657, 10.1007\u002Fs00247-009-1503-3",{"doi":2206},"10.1007\u002Fs00247-009-1503-3",{"id":24,"text":2208,"url":24,"identifiers":2209},"McLean-Tooke, 2007, An unusual cause of granulomatous disease, BMC Clin Pathol, 7, 1, 10.1186\u002F1472-6890-7-1",{"doi":2210},"10.1186\u002F1472-6890-7-1",{"id":24,"text":2212,"url":24,"identifiers":2213},"Brunner, 2007, X-linked chronic granulomatous disease (CGD) caused by an intra-exonic splice mutation (CYBB exon 3, c.262G->A) is mimicking juvenile sarcoidosis, Clin Exp Rheumatol, 25, 336",{},{"id":24,"text":2215,"url":24,"identifiers":2216},"Hauck, 2008, Chronic granulomatous disease (CGD) mimicking neoplasms: a suspected mediastinal teratoma unmasking as thymic granulomas due to X-linked CGD, and 2 related cases, J Pediatr Hematol Oncol, 30, 877, 10.1097\u002FMPH.0b013e31818ab153",{"doi":2217},"10.1097\u002FMPH.0b013e31818ab153",{"id":24,"text":2219,"url":24,"identifiers":2220},"Ameratunga, 2010, Fulminant mulch pneumonitis in undiagnosed chronic granulomatous disease: a medical emergency, Clin Pediatr (Phila), 49, 1143, 10.1177\u002F0009922810370057",{"doi":2221},"10.1177\u002F0009922810370057",{"id":24,"text":2223,"url":24,"identifiers":2224},"Jarukitsopa, 2015, Epidemiology of systemic lupus erythematosus and cutaneous lupus erythematosus in a predominantly white population in the United States, Arthritis Care Res (Hoboken), 67, 817, 10.1002\u002Facr.22502",{"doi":2225},"10.1002\u002Facr.22502",{"id":24,"text":2227,"url":24,"identifiers":2228},"Claps, 2014, How should eosinophilic cystitis be treated in patients with chronic granulomatous disease, Pediatr Nephrol, 29, 2229, 10.1007\u002Fs00467-014-2883-7",{"doi":2229},"10.1007\u002Fs00467-014-2883-7",{"id":24,"text":2231,"url":24,"identifiers":2232},"Dunogué, 2017, Chronic granulomatous disease in patients reaching adulthood: a nationwide study in France, Clin Infect Dis, 64, 767, 10.1093\u002Fcid\u002Fciw837",{"doi":2233},"10.1093\u002Fcid\u002Fciw837",{"id":24,"text":2235,"url":24,"identifiers":2236},"Kang, 2011, Chronic granulomatous disease: overview and hematopoietic stem cell transplantation, J Allergy Clin Immunol, 127, 1319, 10.1016\u002Fj.jaci.2011.03.028",{"doi":2237},"10.1016\u002Fj.jaci.2011.03.028",{"id":24,"text":2239,"url":24,"identifiers":2240},"Chowdhury, 2000, The dermatosis of chronic granulomatous disease, Clin Exp Dermatol, 25, 190, 10.1046\u002Fj.1365-2230.2000.00610.x",{"doi":2241},"10.1046\u002Fj.1365-2230.2000.00610.x",{"id":24,"text":2243,"url":24,"identifiers":2244},"Köker, 2013, Clinical, functional, and genetic characterization of chronic granulomatous disease in 89 Turkish patients, J Allergy Clin Immunol, 132, 1156, 10.1016\u002Fj.jaci.2013.05.039",{"doi":2245},"10.1016\u002Fj.jaci.2013.05.039",{"id":24,"text":2247,"url":24,"identifiers":2248},"Thomsen, 2012, Chronic granulomatous disease masquerading as Behçet disease: a case report and review of the literature, Pediatr Infect Dis J, 31, 529, 10.1097\u002FINF.0b013e3182481ed9",{"doi":2249},"10.1097\u002FINF.0b013e3182481ed9",{"id":24,"text":2251,"url":24,"identifiers":2252},"Parekh, 2011, Hemophagocytic lymphohistiocytosis in children with chronic granulomatous disease, Pediatr Blood Cancer, 56, 460, 10.1002\u002Fpbc.22830",{"doi":2253},"10.1002\u002Fpbc.22830",{"id":24,"text":2255,"url":24,"identifiers":2256},"Holland, 2013, Chronic granulomatous disease, Hematol Oncol Clin North Am, 27, 89, 10.1016\u002Fj.hoc.2012.11.002",{"doi":2257},"10.1016\u002Fj.hoc.2012.11.002",{"id":24,"text":2259,"url":24,"identifiers":2260},"Walther, 1992, The urological manifestations of chronic granulomatous disease, J Urol, 147, 1314, 10.1016\u002FS0022-5347(17)37552-3",{"doi":2261},"10.1016\u002FS0022-5347(17)37552-3",{"id":24,"text":2263,"url":24,"identifiers":2264},"Bauer, 1991, Vesical manifestations of chronic granulomatous disease in children. Its relation to eosinophilic cystitis, Urology, 37, 463, 10.1016\u002F0090-4295(91)80112-K",{"doi":2265},"10.1016\u002F0090-4295(91)80112-K",{"id":24,"text":2267,"url":24,"identifiers":2268},"Redman, 2002, Extensive inflammatory eosinophilic bladder tumors in children: experience with three cases, South Med J, 95, 1050",{},{"id":24,"text":2270,"url":24,"identifiers":2271},"Kontras, 1971, Interstitial cystitis in chronic granulomatous disease, J Urol, 105, 575, 10.1016\u002FS0022-5347(17)61580-5",{"doi":2272},"10.1016\u002FS0022-5347(17)61580-5",{"id":24,"text":2274,"url":24,"identifiers":2275},"Barese, 2004, Recurrent eosinophilic cystitis in a child with chronic granulomatous disease, J Pediatr Hematol Oncol, 26, 209, 10.1097\u002F00043426-200403000-00014",{"doi":2276},"10.1097\u002F00043426-200403000-00014",{"id":24,"text":2278,"url":24,"identifiers":2279},"Macfarlane, 1967, Fatal granulomatous disease of childhood and benign lymphocytic infiltration of the skin (congenital dysphagocytosis), Lancet, 1, 408, 10.1016\u002FS0140-6736(67)91174-9",{"doi":2280},"10.1016\u002FS0140-6736(67)91174-9",{"id":24,"text":2282,"url":24,"identifiers":2283},"Seger, 2008, Modern management of chronic granulomatous disease, Br J Haematol, 140, 255, 10.1111\u002Fj.1365-2141.2007.06880.x",{"doi":2284},"10.1111\u002Fj.1365-2141.2007.06880.x",{"id":24,"text":2286,"url":24,"identifiers":2287},"Feingold, 2016, Thoracic surgery in chronic granulomatous disease: a 25-year single-institution experience, J Clin Immunol, 36, 677, 10.1007\u002Fs10875-016-0319-9",{"doi":2288},"10.1007\u002Fs10875-016-0319-9",{"id":24,"text":2290,"url":24,"identifiers":2291},"Eckert, 1995, The surgical implications of chronic granulomatous disease, Am J Surg, 169, 320, 10.1016\u002FS0002-9610(99)80167-6",{"doi":2292},"10.1016\u002FS0002-9610(99)80167-6",{"id":24,"text":2294,"url":24,"identifiers":2295},"Lublin, 2002, Hepatic abscess in patients with chronic granulomatous disease, Ann Surg, 235, 383, 10.1097\u002F00000658-200203000-00010",{"doi":2296},"10.1097\u002F00000658-200203000-00010",{"id":24,"text":2298,"url":24,"identifiers":2299},"Libert, 2010, The X chromosome in immune functions: when a chromosome makes the difference, Nat Rev Immunol, 10, 594, 10.1038\u002Fnri2815",{"doi":2300},"10.1038\u002Fnri2815",{"id":24,"text":2302,"url":24,"identifiers":2303},"Anderson-Cohen, 2003, Severe phenotype of chronic granulomatous disease presenting in a female with a de novo mutation in gp91-phox and a non familial, extremely skewed X chromosome inactivation, Clin Immunol, 109, 308, 10.1016\u002Fj.clim.2003.08.002",{"doi":2304},"10.1016\u002Fj.clim.2003.08.002",{"id":24,"text":2306,"url":24,"identifiers":2307},"Wolach, 2005, Unusual late presentation of X-linked chronic granulomatous disease in an adult female with a somatic mosaic for a novel mutation in CYBB, Blood, 105, 61, 10.1182\u002Fblood-2004-02-0675",{"doi":2308},"10.1182\u002Fblood-2004-02-0675",{"id":24,"text":2310,"url":24,"identifiers":2311},"Lewis, 2008, X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation, Clin Immunol, 129, 372, 10.1016\u002Fj.clim.2008.07.022",{"doi":2312},"10.1016\u002Fj.clim.2008.07.022",{"id":24,"text":2314,"url":24,"identifiers":2315},"Hauck, 2016, Diagnostic and treatment options for severe IBD in female X-CGD carriers with non-random X-inactivation, J Crohns Colitis, 10, 112, 10.1093\u002Fecco-jcc\u002Fjjv186",{"doi":2316},"10.1093\u002Fecco-jcc\u002Fjjv186",{"id":24,"text":2318,"url":24,"identifiers":2319},"Rösen-Wolff, 2001, Increased susceptibility of a carrier of X-linked chronic granulomatous disease (CGD) to Aspergillus fumigatus infection associated with age-related skewing of lyonization, Ann Hematol, 80, 113, 10.1007\u002Fs002770000230",{"doi":2320},"10.1007\u002Fs002770000230",{"id":24,"text":2322,"url":24,"identifiers":2323},"Battersby, 2017, Inflammatory and autoimmune manifestations in X-linked carriers of chronic granulomatous disease in the United Kingdom, J Allergy Clin Immunol, 140, 628, 10.1016\u002Fj.jaci.2017.02.029",{"doi":2324},"10.1016\u002Fj.jaci.2017.02.029",{"id":24,"text":2326,"url":24,"identifiers":2327},"Battersby, 2013, Clinical manifestations of disease in X-linked carriers of chronic granulomatous disease, J Clin Immunol, 33, 1276, 10.1007\u002Fs10875-013-9939-5",{"doi":2328},"10.1007\u002Fs10875-013-9939-5",{"id":24,"text":2330,"url":24,"identifiers":2331},"Marciano, 2018, X-linked carriers of chronic granulomatous disease: illness, lyonization, and stability, J Allergy Clin Immunol, 141, 365, 10.1016\u002Fj.jaci.2017.04.035",{"doi":2332},"10.1016\u002Fj.jaci.2017.04.035",{"id":24,"text":2334,"url":24,"identifiers":2335},"Goldblatt, 1999, Chorioretinal lesions in patients and carriers of chronic granulomatous disease, J Pediatr, 134, 780, 10.1016\u002FS0022-3476(99)70299-4",{"doi":2336},"10.1016\u002FS0022-3476(99)70299-4",{"id":24,"text":2338,"url":24,"identifiers":2339},"Sillevis Smitt, 1990, Discoid lupus erythematosus-like lesions in carriers of X-linked chronic granulomatous disease, Br J Dermatol, 122, 643, 10.1111\u002Fj.1365-2133.1990.tb07286.x",{"doi":2340},"10.1111\u002Fj.1365-2133.1990.tb07286.x",{"id":24,"text":2342,"url":24,"identifiers":2343},"Brandrup, 1981, Discoid lupus erythematosus-like lesions and stomatitis in female carriers of X-linked chronic granulomatous disease, Br J Dermatol, 104, 495, 10.1111\u002Fj.1365-2133.1981.tb08163.x",{"doi":2344},"10.1111\u002Fj.1365-2133.1981.tb08163.x",{"id":24,"text":2346,"url":24,"identifiers":2347},"Kragballe, 1981, Relation of monocyte and neutrophil oxidative metabolism to skin and oral lesions in carriers of chronic granulomatous disease, Clin Exp Immunol, 43, 390",{},{"id":24,"text":2349,"url":24,"identifiers":2350},"Cale, 2007, Cutaneous and other lupus-like symptoms in carriers of X-linked chronic granulomatous disease: incidence and autoimmune serology, Clin Exp Immunol, 148, 79, 10.1111\u002Fj.1365-2249.2007.03321.x",{"doi":2351},"10.1111\u002Fj.1365-2249.2007.03321.x",{"id":24,"text":2353,"url":24,"identifiers":2354},"Moltyaner, 2003, Underlying chronic granulomatous disease in a patient with bronchocentric granulomatosis, Thorax, 58, 1096, 10.1136\u002Fthorax.58.12.1096",{"doi":2355},"10.1136\u002Fthorax.58.12.1096",{"id":24,"text":2357,"url":24,"identifiers":2358},"Foti, 2004, Lupus erythematosus-like lesions in a carrier of X-linked chronic granulomatous disease: a case report and personal considerations, Int J Dermatol, 43, 840, 10.1111\u002Fj.1365-4632.2004.01950.x",{"doi":2359},"10.1111\u002Fj.1365-4632.2004.01950.x",{"id":24,"text":2361,"url":24,"identifiers":2362},"Lekstrom-Himes, 2005, Inhibition of human neutrophil IL-8 production by hydrogen peroxide and dysregulation in chronic granulomatous disease, J Immunol, 174, 411, 10.4049\u002Fjimmunol.174.1.411",{"doi":2363},"10.4049\u002Fjimmunol.174.1.411",{"id":24,"text":2365,"url":24,"identifiers":2366},"van de Veerdonk, 2010, Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease, Proc Natl Acad Sci U S A, 107, 3030, 10.1073\u002Fpnas.0914795107",{"doi":2367},"10.1073\u002Fpnas.0914795107",{"id":24,"text":2369,"url":24,"identifiers":2370},"de Luca, 2014, IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans, Proc Natl Acad Sci U S A, 111, 3526, 10.1073\u002Fpnas.1322831111",{"doi":2371},"10.1073\u002Fpnas.1322831111",{"id":24,"text":2373,"url":24,"identifiers":2374},"Kasahara, 1997, Involvement of reactive oxygen intermediates in spontaneous and CD95 (Fas\u002FAPO-1)-mediated apoptosis of neutrophils, Blood, 89, 1748, 10.1182\u002Fblood.V89.5.1748",{"doi":2375},"10.1182\u002Fblood.V89.5.1748",{"id":24,"text":2377,"url":24,"identifiers":2378},"Rieber, 2012, Current concepts of hyperinflammation in chronic granulomatous disease, Clin Dev Immunol, 2012, 252460, 10.1155\u002F2012\u002F252460",{"doi":2379},"10.1155\u002F2012\u002F252460",{"id":24,"text":2381,"url":24,"identifiers":2382},"Brown, 2003, Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD), J Leukoc Biol, 73, 591, 10.1189\u002Fjlb.1202599",{"doi":2383},"10.1189\u002Fjlb.1202599",{"id":24,"text":2385,"url":24,"identifiers":2386},"Sanford, 2006, Abnormal apoptosis in chronic granulomatous disease and autoantibody production characteristic of lupus, Rheumatology (Oxford), 45, 178, 10.1093\u002Frheumatology\u002Fkei135",{"doi":2387},"10.1093\u002Frheumatology\u002Fkei135",{"id":24,"text":2389,"url":24,"identifiers":2390},"Singel, 2016, NOX2-dependent regulation of inflammation, Clin Sci (Lond), 130, 479, 10.1042\u002FCS20150660",{"doi":2391},"10.1042\u002FCS20150660",{"id":24,"text":2393,"url":24,"identifiers":2394},"Harbort, 2015, Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis, Blood, 126, 2842, 10.1182\u002Fblood-2015-05-645424",{"doi":2395},"10.1182\u002Fblood-2015-05-645424",{"id":24,"text":2397,"url":24,"identifiers":2398},"Sanmun, 2009, Involvement of a functional NADPH oxidase in neutrophils and macrophages during programmed cell clearance: implications for chronic granulomatous disease, Am J Physiol Cell Physiol, 297, C621, 10.1152\u002Fajpcell.00651.2008",{"doi":2399},"10.1152\u002Fajpcell.00651.2008",{"id":24,"text":2401,"url":24,"identifiers":2402},"Fernandez-Boyanapalli, 2015, Impaired efferocytosis in human chronic granulomatous disease is reversed by pioglitazone treatment, J Allergy Clin Immunol, 136, 1399, 10.1016\u002Fj.jaci.2015.07.034",{"doi":2403},"10.1016\u002Fj.jaci.2015.07.034",{"id":24,"text":2405,"url":24,"identifiers":2406},"Foster, 1998, Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease, J Clin Invest, 102, 2146, 10.1172\u002FJCI5084",{"doi":2407},"10.1172\u002FJCI5084",{"id":24,"text":2409,"url":24,"identifiers":2410},"Sibley, 2014, Assessment of atherosclerosis in chronic granulomatous disease, Circulation, 130, 2031, 10.1161\u002FCIRCULATIONAHA.113.006824",{"doi":2411},"10.1161\u002FCIRCULATIONAHA.113.006824",{"id":24,"text":2413,"url":24,"identifiers":2414},"Jaggi, 2012, Utility of screening for chronic granulomatous disease in patients with inflammatory bowel disease, J Clin Immunol, 32, 78, 10.1007\u002Fs10875-011-9608-5",{"doi":2415},"10.1007\u002Fs10875-011-9608-5",{"id":24,"text":2417,"url":24,"identifiers":2418},"Sullivan, 2014, USIDNET: a strategy to build a community of clinical immunologists, J Clin Immunol, 34, 428, 10.1007\u002Fs10875-014-0028-1",{"doi":2419},"10.1007\u002Fs10875-014-0028-1",{"id":2421,"createTime":2422,"updateTime":2422,"relativeEntities":2423,"slug":2424,"properties":2425,"entityType":141,"verifyStatus":142,"verifyTime":2422,"verifyNote":143,"syncStatus":23,"languages":2437,"translateLanguages":24,"viewCount":25,"primaryUrl":2438,"fullTextUrl":24,"authors":2439,"publicationType":398,"publisherRelationship":3302,"citationCount":3335,"citationInfo":3336,"publishDate":3338,"publishYear":3339,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":3340,"isForceReanalyzing":462},"55a5bb46-7c6b-47aa-ab3d-e5d4e36b4145","2024-10-11T05:52:20.562+00:00",[],"Multicenter-Interim-Guidance-on-Use-of-Antivirals-for-Children-With-Coronavirus-Disease-2019-Severe-Acute-Respiratory-Syndrome-Coronavirus-2",{"keywords":2426,"openalex":2427,"abstract":2429,"title":2431,"pm":2433,"doi":2435},{},{"VOID":2428},"W4206405674",{"EN":2430},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:title>Background\u003C\u002Fjats:title>\u003Cjats:p>Although coronavirus disease 2019 (COVID-19) is a mild infection in most children, a small proportion develop severe or critical illness. Data describing agents with potential antiviral activity continue to expand such that updated guidance is needed regarding use of these agents in children.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods\u003C\u002Fjats:title>\u003Cjats:p>A panel of pediatric infectious diseases physicians and pharmacists from 20 geographically diverse North American institutions was convened. Through a series of teleconferences and web-based surveys, a set of guidance statements was developed and refined based on review of the best available evidence and expert opinion.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>Given the typically mild course of COVID-19 in children, supportive care alone is suggested for most cases. For children with severe illness, defined as a supplemental oxygen requirement without need for noninvasive or invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO), remdesivir is suggested, preferably as part of a clinical trial if available. Remdesivir should also be considered for critically ill children requiring invasive or noninvasive mechanical ventilation or ECMO. A duration of 5 days is appropriate for most patients. The panel recommends against the use of hydroxychloroquine or lopinavir-ritonavir (or other protease inhibitors) for COVID-19 in children.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>Antiviral therapy for COVID-19 is not necessary for the great majority of pediatric patients. For children with severe or critical disease, this guidance offers an approach for decision-making regarding use of remdesivir.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":2432},"Multicenter Interim Guidance on Use of Antivirals for Children With Coronavirus Disease 2019\u002FSevere Acute Respiratory Syndrome Coronavirus 2",{"VOID":2434},"32918548",{"VOID":2436},"10.1093\u002Fjpids\u002Fpiaa115",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F10\u002F1\u002F34\u002F5904884",[2440,2472,2494,2516,2537,2558,2596,2617,2639,2658,2683,2706,2729,2751,2773,2788,2807,2829,2851,2868,2891,2923,2940,2957,2975,2996,3017,3046,3067,3089,3110,3133,3151,3168,3188,3204,3226,3247,3262,3284],{"id":2441,"sortIndex":2442,"researcher":24,"roles":2443,"affiliations":2444,"properties":2465},"ae929333-b075-4d83-8ea7-5d8e18a62d76",39,[],[2445,2455],{"id":2446,"sortIndex":166,"affiliation":2447,"properties":24},"4f950855-0384-4f91-ac53-59b3c1821b52",{"id":2448,"createTime":2449,"updateTime":2449,"relativeEntities":2450,"slug":2451,"properties":2452,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"28665114-bf6f-4144-a458-c8cd01ccfb94","2024-10-11T05:52:20.739+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Boston-Children-s-Hospital-Boston-Massachusetts-USA",{"title":2453},{"EN":2454},"Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA",{"id":2456,"sortIndex":25,"affiliation":2457,"properties":24},"3ada12f6-0386-48fc-9d49-a943bded578a",{"id":2458,"createTime":2459,"updateTime":2459,"relativeEntities":2460,"slug":2461,"properties":2462,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"784ef4a6-7cf1-45d0-88e5-07979bfa163a","2024-10-11T05:52:20.668+00:00",[],"Antimicrobial-Stewardship-Program-Boston-Children-s-Hospital-Boston-Massachusetts-USA",{"title":2463},{"EN":2464},"Antimicrobial Stewardship Program, Boston Children's Hospital, Boston, Massachusetts, USA",{"openalex":2466,"orcid":2468,"title":2470},{"VOID":2467},"A5020385033",{"VOID":2469},"https:\u002F\u002Forcid.org\u002F0000-0002-8191-0027",{"EN":2471},"Mari Nakamura",{"id":2473,"sortIndex":2474,"researcher":24,"roles":2475,"affiliations":2476,"properties":2487},"b5b8c29f-d87a-4d0e-a6c5-3e7bb2e5a2f3",17,[],[2477],{"id":2478,"sortIndex":25,"affiliation":2479,"properties":24},"c89adb36-d359-41b3-8e3c-e58a892f469c",{"id":2480,"createTime":2481,"updateTime":2481,"relativeEntities":2482,"slug":2483,"properties":2484,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"fae68371-baf8-4bd2-ac90-7893d8377414","2024-10-11T05:52:20.640+00:00",[],"Department-of-Pharmacy-Lucile-Packard-Children-s-Hospital-Stanford-Palo-Alto-California-USA",{"title":2485},{"EN":2486},"Department of Pharmacy, Lucile Packard Children's Hospital Stanford, Palo Alto, California, USA",{"openalex":2488,"orcid":2490,"title":2492},{"VOID":2489},"A5088752736",{"VOID":2491},"https:\u002F\u002Forcid.org\u002F0000-0001-9520-6420",{"EN":2493},"Laura L. Bio",{"id":2495,"sortIndex":2496,"researcher":24,"roles":2497,"affiliations":2498,"properties":2509},"c4f5bbfc-aaa7-43d9-96c6-940b535432e8",24,[],[2499],{"id":2500,"sortIndex":25,"affiliation":2501,"properties":24},"9cbe1f4a-5e53-4d96-a658-f8fbcc7f1c5f",{"id":2502,"createTime":2503,"updateTime":2503,"relativeEntities":2504,"slug":2505,"properties":2506,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6bc64dbe-ab65-4b1c-ba24-ce03ca1bc1f0","2024-10-11T05:52:20.691+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Washington-University-and-St-Louis-Children-s-Hospital-St-Louis-Missouri-USA",{"title":2507},{"EN":2508},"Division of Infectious Diseases, Department of Pediatrics, Washington University and St. Louis Children's Hospital, St. Louis, Missouri, USA",{"openalex":2510,"orcid":2512,"title":2514},{"VOID":2511},"A5017147084",{"VOID":2513},"https:\u002F\u002Forcid.org\u002F0000-0003-3865-2728",{"EN":2515},"Rachel C. Orscheln",{"id":2517,"sortIndex":435,"researcher":24,"roles":2518,"affiliations":2519,"properties":2530},"4d53360d-9022-4c2d-aa0c-066400753977",[],[2520],{"id":2521,"sortIndex":25,"affiliation":2522,"properties":24},"46102776-7338-4768-bf8c-f3044471c833",{"id":2523,"createTime":2524,"updateTime":2524,"relativeEntities":2525,"slug":2526,"properties":2527,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"486a15fd-7022-405c-b289-b3a436c128ac","2024-10-11T05:52:20.611+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Vanderbilt-University-and-Monroe-Carell-Jr-Children-s-Hospital-Nashville-Tennessee-USA",{"title":2528},{"EN":2529},"Division of Infectious Diseases, Department of Pediatrics, Vanderbilt University and Monroe Carell Jr. Children's Hospital, Nashville, Tennessee, USA",{"openalex":2531,"orcid":2533,"title":2535},{"VOID":2532},"A5081978275",{"VOID":2534},"https:\u002F\u002Forcid.org\u002F0000-0003-2655-0900",{"EN":2536},"Mark R. Denison",{"id":2538,"sortIndex":209,"researcher":24,"roles":2539,"affiliations":2540,"properties":2551},"9fceb29e-73f9-4171-b9d8-a7dbeb75043e",[],[2541],{"id":2542,"sortIndex":25,"affiliation":2543,"properties":24},"d257f216-aaeb-400a-8161-708b26274665",{"id":2544,"createTime":2545,"updateTime":2545,"relativeEntities":2546,"slug":2547,"properties":2548,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6943df44-86a7-4953-97d2-1876ea7a6704","2024-10-11T05:52:20.575+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatrics-University-of-Alabama-at-Birmingham-Birmingham-Alabama-USA",{"title":2549},{"EN":2550},"Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA",{"openalex":2552,"orcid":2554,"title":2556},{"VOID":2553},"A5037870463",{"VOID":2555},"https:\u002F\u002Forcid.org\u002F0000-0001-9038-9109",{"EN":2557},"David W. Kimberlin",{"id":2559,"sortIndex":25,"researcher":24,"roles":2560,"affiliations":2561,"properties":2592},"1601e6ed-f9fc-403d-b3f4-75024d478fa1",[],[2562,2572,2582],{"id":2563,"sortIndex":209,"affiliation":2564,"properties":24},"d83a4c4b-7658-4163-bec9-272278859165",{"id":2565,"createTime":2566,"updateTime":2566,"relativeEntities":2567,"slug":2568,"properties":2569,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"9e06e2e6-bd47-48fb-87e9-4cb45ec5cddc","2024-10-11T05:52:20.592+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":2570},{"EN":2571},"Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"id":2573,"sortIndex":166,"affiliation":2574,"properties":24},"833ad08e-7af6-4207-9dae-b7fd5e995091",{"id":2575,"createTime":2576,"updateTime":2576,"relativeEntities":2577,"slug":2578,"properties":2579,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"caf5330a-f144-4d53-a030-fa664eec11f7","2024-10-11T05:52:20.588+00:00",[],"Division-of-Critical-Care-Medicine-Department-of-Anesthesia-and-Critical-Care-Medicine-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":2580},{"EN":2581},"Division of Critical Care Medicine, Department of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"id":2583,"sortIndex":25,"affiliation":2584,"properties":24},"b0d23d1a-0541-43c0-ae9d-8499fd2cba87",{"id":2585,"createTime":2586,"updateTime":2586,"relativeEntities":2587,"slug":2588,"properties":2589,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"ad8f4664-c873-48a1-9382-0e92e2e9cff6","2024-10-11T05:52:20.584+00:00",[],"Antimicrobial-Stewardship-Program-Children-s-Hospital-of-Philadelphia-Philadelphia-Pennsylvania-USA",{"title":2590},{"EN":2591},"Antimicrobial Stewardship Program, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA",{"openalex":2593,"orcid":2594,"title":2595},{"VOID":1471},{"VOID":1473},{"EN":1475},{"id":2597,"sortIndex":581,"researcher":24,"roles":2598,"affiliations":2599,"properties":2610},"51bc0483-3867-4e0e-b484-c3d169cf849d",[],[2600],{"id":2601,"sortIndex":25,"affiliation":2602,"properties":24},"48b67214-e863-4bc6-b4b4-dfc20b868e05",{"id":2603,"createTime":2604,"updateTime":2604,"relativeEntities":2605,"slug":2606,"properties":2607,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"9a468bc0-fb36-4a3a-afc0-eb7586514c07","2024-10-11T05:52:20.963+00:00",[],"Section-of-Infectious-Diseases-Department-of-Pediatrics-and-Human-Development-Helen-DeVos-Children-s-Hospital-of-Spectrum-Health-Michigan-State-College-of-Human-Medicine-Grand-Rapids-Michigan-USA",{"title":2608},{"EN":2609},"Section of Infectious Diseases, Department of Pediatrics and Human Development, Helen DeVos Children's Hospital of Spectrum Health, Michigan State College of Human Medicine, Grand Rapids, Michigan, USA",{"openalex":2611,"orcid":2613,"title":2615},{"VOID":2612},"A5037868504",{"VOID":2614},"https:\u002F\u002Forcid.org\u002F0000-0002-5417-4650",{"EN":2616},"Rosemary Olivero",{"id":2618,"sortIndex":2619,"researcher":24,"roles":2620,"affiliations":2621,"properties":2632},"45c4e2a5-1fac-4603-a347-61888ac79929",33,[],[2622],{"id":2623,"sortIndex":25,"affiliation":2624,"properties":24},"077eb5a2-def3-40d2-9008-2418c968a66b",{"id":2625,"createTime":2626,"updateTime":2626,"relativeEntities":2627,"slug":2628,"properties":2629,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6ba5c06b-754f-4de9-9a2e-26a7c189f03f","2024-10-11T05:52:20.920+00:00",[],"Department-of-Pediatrics-Division-of-Infectious-Diseases-University-of-Michigan-and-CS-Mott-Children-s-Hospital-Ann-Arbor-Michigan-USA",{"title":2630},{"EN":2631},"Department of Pediatrics, Division of Infectious Diseases, University of Michigan and CS Mott Children's Hospital, Ann Arbor, Michigan, USA",{"openalex":2633,"orcid":2635,"title":2637},{"VOID":2634},"A5080720503",{"VOID":2636},"https:\u002F\u002Forcid.org\u002F0000-0003-2357-8190",{"EN":2638},"Alison C. Tribble",{"id":2640,"sortIndex":185,"researcher":24,"roles":2641,"affiliations":2642,"properties":2653},"71d92c07-97db-467e-8452-469765fda29d",[],[2643],{"id":2644,"sortIndex":25,"affiliation":2645,"properties":24},"e4bfaec8-649f-444e-a4a1-28b3a8357003",{"id":2646,"createTime":2647,"updateTime":2647,"relativeEntities":2648,"slug":2649,"properties":2650,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"85d8b24d-d84d-45de-87a9-f768d208272c","2024-10-11T05:52:20.752+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-New-York-University-Grossman-School-of-Medicine-and-Hassenfeld-Children-s-Hospital-New-York-New-York-USA",{"title":2651},{"EN":2652},"Division of Infectious Diseases, Department of Pediatrics, New York University Grossman School of Medicine and Hassenfeld Children's Hospital, New York, New York, USA",{"openalex":2654,"title":2656},{"VOID":2655},"A5020021042",{"EN":2657},"Vijaya L. Soma",{"id":2659,"sortIndex":233,"researcher":24,"roles":2660,"affiliations":2661,"properties":2678},"80fe0b91-7a1c-4f83-bc0a-7642496c9f88",[],[2662,2668],{"id":2663,"sortIndex":25,"affiliation":2664,"properties":24},"64cbbeb9-1d0e-4c7b-987f-78e921be2953",{"id":2458,"createTime":2459,"updateTime":2459,"relativeEntities":2665,"slug":2461,"properties":2666,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":2667},{"EN":2464},{"id":2669,"sortIndex":166,"affiliation":2670,"properties":24},"69ed54bb-9af2-4027-a11b-59609815bdf0",{"id":2671,"createTime":2672,"updateTime":2672,"relativeEntities":2673,"slug":2674,"properties":2675,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"cf48de40-651d-4f2e-8b1a-33ff12c2891e","2024-10-11T05:52:20.671+00:00",[],"Department-of-Pharmacy-Boston-Children-s-Hospital-Boston-Massachusetts-USA",{"title":2676},{"EN":2677},"Department of Pharmacy, Boston Children's Hospital, Boston, Massachusetts, USA",{"openalex":2679,"title":2681},{"VOID":2680},"A5073760129",{"EN":2682},"Sarah Bruyn Jones",{"id":2684,"sortIndex":2685,"researcher":24,"roles":2686,"affiliations":2687,"properties":2699},"11f6c7d1-ef2c-491b-9b8c-dd4aeeceeed8",21,[],[2688],{"id":2689,"sortIndex":25,"affiliation":2690,"properties":24},"c423a0d8-420c-44f1-8050-97c4ff0ce8cf",{"id":2691,"createTime":2692,"updateTime":2693,"relativeEntities":2694,"slug":2695,"properties":2696,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"7b296cb1-b72e-49bb-96d4-c2ff31bdc8d2","2023-12-27T01:34:17.043+00:00","2024-10-11T05:52:20.786+00:00",[],"Yale-University-School-of-Medicine-Yale-University-New-Haven-Connecticut-USA",{"title":2697},{"VI":2698},"Yale University School of Medicine, Yale University, New Haven, Connecticut, USA",{"openalex":2700,"orcid":2702,"title":2704},{"VOID":2701},"A5015187790",{"VOID":2703},"https:\u002F\u002Forcid.org\u002F0000-0003-1897-6581",{"EN":2705},"Carlos R. Oliveira",{"id":2707,"sortIndex":2708,"researcher":24,"roles":2709,"affiliations":2710,"properties":2722},"2f47401b-d415-4a5e-8e9e-763f609dc52e",31,[],[2711],{"id":2712,"sortIndex":25,"affiliation":2713,"properties":24},"d9cca353-fb0d-4aa9-b044-a32831daf94b",{"id":2714,"createTime":2715,"updateTime":2716,"relativeEntities":2717,"slug":2718,"properties":2719,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"00f72831-e4d6-4fdd-ba20-37224832d547","2024-10-11T05:52:21.002+00:00","2025-06-11T14:26:48.550+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatric-and-Adolescent-Medicine-Mayo-Clinic-Rochester-Minnesota-USA",{"title":2720},{"EN":2721},"Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA",{"openalex":2723,"orcid":2725,"title":2727},{"VOID":2724},"A5084893577",{"VOID":2726},"https:\u002F\u002Forcid.org\u002F0000-0001-9286-2473",{"EN":2728},"Nipunie Rajapakse",{"id":2730,"sortIndex":2731,"researcher":24,"roles":2732,"affiliations":2733,"properties":2744},"8facefd0-bc40-448c-acd1-0a809ded65ca",25,[],[2734],{"id":2735,"sortIndex":25,"affiliation":2736,"properties":24},"458f4be9-0410-4541-9cce-0d11fc09c0e3",{"id":2737,"createTime":2738,"updateTime":2738,"relativeEntities":2739,"slug":2740,"properties":2741,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"cb53df58-8bd1-47e9-b218-ce7e73a0f811","2024-10-11T05:52:20.651+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Johns-Hopkins-University-School-of-Medicine-Baltimore-Maryland-USA",{"title":2742},{"EN":2743},"Division of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA",{"openalex":2745,"orcid":2747,"title":2749},{"VOID":2746},"A5030280540",{"VOID":2748},"https:\u002F\u002Forcid.org\u002F0000-0002-4143-6324",{"EN":2750},"Pranita D. Tamma",{"id":2752,"sortIndex":508,"researcher":24,"roles":2753,"affiliations":2754,"properties":2766},"bcdf0aad-82af-48ac-b2ca-8552be2562f4",[],[2755],{"id":2756,"sortIndex":25,"affiliation":2757,"properties":24},"adcf5c0e-9c2e-4be5-8456-78631799b645",{"id":2758,"createTime":2759,"updateTime":2760,"relativeEntities":2761,"slug":2762,"properties":2763,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"1899c007-3056-41c7-9162-3eeb8463aec3","2023-12-11T07:36:20.453+00:00","2024-12-23T05:32:41.194+00:00",[],"Department-of-Infectious-Diseases-St-Jude-Children-s-Research-Hospital-Memphis-Tennessee-USA",{"title":2764},{"VI":2765},"Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee, USA",{"openalex":2767,"orcid":2769,"title":2771},{"VOID":2768},"A5107220267",{"VOID":2770},"https:\u002F\u002Forcid.org\u002F0000-0002-9912-3646",{"EN":2772},"Joshua Wolf",{"id":2774,"sortIndex":62,"researcher":24,"roles":2775,"affiliations":2776,"properties":2783},"fee9277a-fca3-4186-972c-413ce3d3bfc3",[],[2777],{"id":2778,"sortIndex":25,"affiliation":2779,"properties":24},"acaa168a-7848-457b-a7d6-5f94dc4a6e9b",{"id":2544,"createTime":2545,"updateTime":2545,"relativeEntities":2780,"slug":2547,"properties":2781,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":2782},{"EN":2550},{"openalex":2784,"title":2786},{"VOID":2785},"A5103882151",{"EN":2787},"Scott H. James",{"id":2789,"sortIndex":792,"researcher":24,"roles":2790,"affiliations":2791,"properties":2802},"d96e53eb-c56d-42a4-8b78-34916204e564",[],[2792],{"id":2793,"sortIndex":25,"affiliation":2794,"properties":24},"611bd93c-224d-4607-8378-2dd12335756b",{"id":2795,"createTime":2796,"updateTime":2796,"relativeEntities":2797,"slug":2798,"properties":2799,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"b8c72a43-8279-4bf0-ab95-83cbe6279247","2024-10-11T05:52:20.601+00:00",[],"Department-of-Pharmacy-University-of-California-San-Francisco-Benioff-Children-s-Hospital-San-Francisco-California-USA",{"title":2800},{"EN":2801},"Department of Pharmacy, University of California–San Francisco Benioff Children’s Hospital, San Francisco, California, USA",{"openalex":2803,"title":2805},{"VOID":2804},"A5082362014",{"EN":2806},"Steven P Grapentine",{"id":2808,"sortIndex":2809,"researcher":24,"roles":2810,"affiliations":2811,"properties":2822},"14dd7b04-0906-4126-9144-64755e8b07ca",30,[],[2812],{"id":2813,"sortIndex":25,"affiliation":2814,"properties":24},"d0ab00b0-dd1c-445a-8003-f0957928b408",{"id":2815,"createTime":2816,"updateTime":2816,"relativeEntities":2817,"slug":2818,"properties":2819,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"ebe1a6e5-09a2-4456-9dd4-9b76b875738b","2024-10-11T05:52:20.952+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Hospital-for-Sick-Children-Toronto-Ontario-Canada",{"title":2820},{"EN":2821},"Division of Infectious Diseases, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada",{"openalex":2823,"orcid":2825,"title":2827},{"VOID":2824},"A5068423549",{"VOID":2826},"https:\u002F\u002Forcid.org\u002F0000-0001-9244-9961",{"EN":2828},"Helen Groves",{"id":2830,"sortIndex":2831,"researcher":24,"roles":2832,"affiliations":2833,"properties":2844},"0c04dc41-f603-45ae-9c74-4ded592aeba1",34,[],[2834],{"id":2835,"sortIndex":25,"affiliation":2836,"properties":24},"ccbc145b-a0d3-4207-bc1b-e8fb029ae9fc",{"id":2837,"createTime":2838,"updateTime":2838,"relativeEntities":2839,"slug":2840,"properties":2841,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"f4ad249a-7860-4356-b62f-3bc784e8c5a1","2024-10-11T05:52:20.630+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-University-of-Utah-and-Primary-Children-s-Hospital-Salt-Lake-City-Utah-USA",{"title":2842},{"EN":2843},"Division of Infectious Diseases, Department of Pediatrics, University of Utah and Primary Children's Hospital, Salt Lake City, Utah, USA",{"openalex":2845,"orcid":2847,"title":2849},{"VOID":2846},"A5083082437",{"VOID":2848},"https:\u002F\u002Forcid.org\u002F0000-0002-0148-046X",{"EN":2850},"Adam L. Hersh",{"id":2852,"sortIndex":166,"researcher":24,"roles":2853,"affiliations":2854,"properties":2861},"835a1b81-ca6d-4ca6-aa82-d576b3e49080",[],[2855],{"id":2856,"sortIndex":25,"affiliation":2857,"properties":24},"34054d62-6f02-452b-92e5-da5b0e331a9e",{"id":2585,"createTime":2586,"updateTime":2586,"relativeEntities":2858,"slug":2588,"properties":2859,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":2860},{"EN":2591},{"openalex":2862,"orcid":2864,"title":2866},{"VOID":2863},"A5048183227",{"VOID":2865},"https:\u002F\u002Forcid.org\u002F0000-0003-3270-6633",{"EN":2867},"Molly Hayes",{"id":2869,"sortIndex":2870,"researcher":24,"roles":2871,"affiliations":2872,"properties":2884},"3fc14af3-58ea-416c-986a-c563b5c8b404",16,[],[2873],{"id":2874,"sortIndex":25,"affiliation":2875,"properties":24},"aa4e562d-3ee5-459c-9a7b-be3f14270768",{"id":2876,"createTime":2877,"updateTime":2878,"relativeEntities":2879,"slug":2880,"properties":2881,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"063769de-dbef-4f5a-9954-f66af3a59579","2024-10-11T05:52:20.909+00:00","2025-06-11T19:18:56.634+00:00",[],"Division-of-Infectious-Diseases-and-Global-Health-Department-of-Pediatrics-University-of-California-San-Francisco-San-Francisco-California-USA",{"title":2882},{"EN":2883},"Division of Infectious Diseases and Global Health, Department of Pediatrics, University of California–San Francisco, San Francisco, California, USA",{"openalex":2885,"orcid":2887,"title":2889},{"VOID":2886},"A5048890076",{"VOID":2888},"https:\u002F\u002Forcid.org\u002F0000-0002-5271-4705",{"EN":2890},"Rachel L Wattier",{"id":2892,"sortIndex":706,"researcher":24,"roles":2893,"affiliations":2894,"properties":2916},"871d80aa-0065-4038-91ef-38127033ce78",[],[2895,2905],{"id":2896,"sortIndex":25,"affiliation":2897,"properties":24},"7c1e70ed-a202-471b-90dd-96a986c63869",{"id":2898,"createTime":2899,"updateTime":2899,"relativeEntities":2900,"slug":2901,"properties":2902,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"85a0cb14-985a-4384-9a72-001ffa5bdee0","2024-10-11T05:52:20.932+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatrics-University-of-Washington-Seattle-Children-s-Hospital-Seattle-Washington-USA",{"title":2903},{"EN":2904},"Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Washington, Seattle Children's Hospital, Seattle, Washington, USA",{"id":2906,"sortIndex":166,"affiliation":2907,"properties":24},"b6b6a8f2-4257-4c39-ac96-17176f184052",{"id":2908,"createTime":2909,"updateTime":2910,"relativeEntities":2911,"slug":2912,"properties":2913,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"56f92cfd-ccc4-453a-bca6-f79f7aa1a0b5","2024-10-11T05:52:20.992+00:00","2024-12-25T12:25:19.537+00:00",[],"Vaccine-and-Infectious-Diseases-Division-Fred-Hutchinson-Cancer-Research-Center-Seattle-Washington-USA",{"title":2914},{"EN":2915},"Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA",{"openalex":2917,"orcid":2919,"title":2921},{"VOID":2918},"A5045590132",{"VOID":2920},"https:\u002F\u002Forcid.org\u002F0000-0003-2268-9470",{"EN":2922},"Alpana Waghmare",{"id":2924,"sortIndex":620,"researcher":24,"roles":2925,"affiliations":2926,"properties":2933},"26ac601a-b394-4661-a73c-81a77c50c292",[],[2927],{"id":2928,"sortIndex":25,"affiliation":2929,"properties":24},"c4fc86b3-d426-4d5f-b8e8-be0c90e21b1d",{"id":2898,"createTime":2899,"updateTime":2899,"relativeEntities":2930,"slug":2901,"properties":2931,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":2932},{"EN":2904},{"openalex":2934,"orcid":2936,"title":2938},{"VOID":2935},"A5043912225",{"VOID":2937},"https:\u002F\u002Forcid.org\u002F0000-0002-9344-5185",{"EN":2939},"Surabhi B Vora",{"id":2941,"sortIndex":354,"researcher":24,"roles":2942,"affiliations":2943,"properties":2950},"816b96b0-1c3b-490c-a76a-cf6712ab07d0",[],[2944],{"id":2945,"sortIndex":25,"affiliation":2946,"properties":24},"a8207ee8-4976-497c-b1d6-db39bfd41395",{"id":2523,"createTime":2524,"updateTime":2524,"relativeEntities":2947,"slug":2526,"properties":2948,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":2949},{"EN":2529},{"openalex":2951,"orcid":2953,"title":2955},{"VOID":2952},"A5085486817",{"VOID":2954},"https:\u002F\u002Forcid.org\u002F0000-0002-1821-6657",{"EN":2956},"Daniel E. Dulek",{"id":2958,"sortIndex":2959,"researcher":24,"roles":2960,"affiliations":2961,"properties":2968},"bf59f168-942c-456d-a6e3-01c085a65ab9",32,[],[2962],{"id":2963,"sortIndex":25,"affiliation":2964,"properties":24},"a46ba18f-44f6-4b1e-a677-e0e41a1c7423",{"id":2448,"createTime":2449,"updateTime":2449,"relativeEntities":2965,"slug":2451,"properties":2966,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":2967},{"EN":2454},{"openalex":2969,"orcid":2971,"title":2973},{"VOID":2970},"A5074292612",{"VOID":2972},"https:\u002F\u002Forcid.org\u002F0000-0002-8738-9383",{"EN":2974},"Gabriella S Lamb",{"id":2976,"sortIndex":294,"researcher":24,"roles":2977,"affiliations":2978,"properties":2989},"8f81cac4-918f-400c-a5d7-b06c591b1059",[],[2979],{"id":2980,"sortIndex":25,"affiliation":2981,"properties":24},"274d7859-033c-4280-ba0f-ef8681714c4c",{"id":2982,"createTime":2983,"updateTime":2983,"relativeEntities":2984,"slug":2985,"properties":2986,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"be6153cf-aef5-4e16-b226-3dfd2a5ba7ff","2024-10-11T05:52:15.503+00:00",[],"Department-of-Pharmacy-Children-s-of-Alabama-Birmingham-Alabama-USA",{"title":2987},{"EN":2988},"Department of Pharmacy, Children's of Alabama, Birmingham, Alabama, USA",{"openalex":2990,"orcid":2992,"title":2994},{"VOID":2991},"A5017558263",{"VOID":2993},"https:\u002F\u002Forcid.org\u002F0000-0003-1892-8344",{"EN":2995},"April Yarbrough",{"id":2997,"sortIndex":993,"researcher":24,"roles":2998,"affiliations":2999,"properties":3010},"8ba709fc-1306-424d-bfd9-5b3e6b40840c",[],[3000],{"id":3001,"sortIndex":25,"affiliation":3002,"properties":24},"0a7ca27f-2702-4d03-8d85-f79d07e0abf9",{"id":3003,"createTime":3004,"updateTime":3004,"relativeEntities":3005,"slug":3006,"properties":3007,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"4db3841c-be48-4d03-bb56-5fdc15a3458e","2024-10-11T05:52:21.026+00:00",[],"Department-of-Pharmacy-CS-Mott-Children-s-Hospital-Ann-Arbor-Michigan-USA",{"title":3008},{"EN":3009},"Department of Pharmacy, CS Mott Children's Hospital, Ann Arbor, Michigan, USA",{"openalex":3011,"orcid":3013,"title":3015},{"VOID":3012},"A5025263192",{"VOID":3014},"https:\u002F\u002Forcid.org\u002F0000-0003-2334-9478",{"EN":3016},"Nicholas O. Dillman",{"id":3018,"sortIndex":3019,"researcher":24,"roles":3020,"affiliations":3021,"properties":3039},"b6c0907f-3a64-46b4-aaae-f12fea7b919b",37,[],[3022,3028],{"id":3023,"sortIndex":166,"affiliation":3024,"properties":24},"da64bb9e-d915-4536-b621-4e0021a27e1d",{"id":2646,"createTime":2647,"updateTime":2647,"relativeEntities":3025,"slug":2649,"properties":3026,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3027},{"EN":2652},{"id":3029,"sortIndex":25,"affiliation":3030,"properties":24},"d36c1426-d91d-4100-8f12-066780ab201c",{"id":3031,"createTime":3032,"updateTime":3033,"relativeEntities":3034,"slug":3035,"properties":3036,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"0f26d4f8-c07f-4581-8a6e-8b7c152a1979","2024-01-06T23:56:57.794+00:00","2024-10-11T05:52:20.749+00:00",[],"Department-of-Microbiology-New-York-University-Grossman-School-of-Medicine-New-York-New-York-USA",{"title":3037},{"VI":3038},"Department of Microbiology, New York University Grossman School of Medicine, New York, New York, USA",{"openalex":3040,"orcid":3042,"title":3044},{"VOID":3041},"A5062265331",{"VOID":3043},"https:\u002F\u002Forcid.org\u002F0000-0003-1761-794X",{"EN":3045},"Adam J. Ratner",{"id":3047,"sortIndex":150,"researcher":24,"roles":3048,"affiliations":3049,"properties":3060},"d94eb528-9797-4985-aba9-a702d0bd4c7d",[],[3050],{"id":3051,"sortIndex":25,"affiliation":3052,"properties":24},"f2d0ec01-fe77-48b6-9c8d-c45f339d3886",{"id":3053,"createTime":3054,"updateTime":3054,"relativeEntities":3055,"slug":3056,"properties":3057,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"231ee04b-d299-420a-a9c1-1172623a86ea","2024-10-11T05:52:20.865+00:00",[],"Department-of-Pharmacy-Children-s-Hospital-Colorado-Aurora-Colorado-USA",{"title":3058},{"EN":3059},"Department of Pharmacy, Children's Hospital Colorado, Aurora, Colorado, USA",{"openalex":3061,"orcid":3063,"title":3065},{"VOID":3062},"A5086010950",{"VOID":3064},"https:\u002F\u002Forcid.org\u002F0000-0002-4893-2224",{"EN":3066},"Taiju Miyagami",{"id":3068,"sortIndex":3069,"researcher":24,"roles":3070,"affiliations":3071,"properties":3082},"14e6b5a8-1585-424f-9dd1-619f5e18e14f",27,[],[3072],{"id":3073,"sortIndex":25,"affiliation":3074,"properties":24},"6fcc030e-7529-4d1b-adb5-7c72301f4782",{"id":3075,"createTime":3076,"updateTime":3076,"relativeEntities":3077,"slug":3078,"properties":3079,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"1b57cc28-f925-4447-9f8e-c085967b8638","2024-10-11T05:52:20.715+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Columbia-University-New-York-New-York-USA",{"title":3080},{"EN":3081},"Division of Infectious Diseases, Department of Pediatrics, Columbia University, New York, New York, USA",{"openalex":3083,"orcid":3085,"title":3087},{"VOID":3084},"A5089507490",{"VOID":3086},"https:\u002F\u002Forcid.org\u002F0000-0002-5080-1573",{"EN":3088},"Philip Zachariah",{"id":3090,"sortIndex":437,"researcher":24,"roles":3091,"affiliations":3092,"properties":3103},"6be82b09-5257-473b-8172-9fbec14eea0c",[],[3093],{"id":3094,"sortIndex":25,"affiliation":3095,"properties":24},"99c1aea7-b91d-40ee-bc3c-68f1c503497c",{"id":3096,"createTime":3097,"updateTime":3097,"relativeEntities":3098,"slug":3099,"properties":3100,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"ee449890-0b3e-4f84-a378-587e772921ca","2024-10-11T05:52:21.015+00:00",[],"Department-of-Pharmacy-St-Louis-Children-s-Hospital-St-Louis-Missouri-USA",{"title":3101},{"EN":3102},"Department of Pharmacy, St. Louis Children's Hospital, St. Louis, Missouri, USA",{"openalex":3104,"orcid":3106,"title":3108},{"VOID":3105},"A5083929997",{"VOID":3107},"https:\u002F\u002Forcid.org\u002F0000-0002-7558-3445",{"EN":3109},"Jennifer L. Young",{"id":3111,"sortIndex":3112,"researcher":24,"roles":3113,"affiliations":3114,"properties":3126},"75c6f91f-6439-4143-a21e-befded886508",22,[],[3115],{"id":3116,"sortIndex":25,"affiliation":3117,"properties":24},"1c5d97b2-525c-4e35-af3d-1c1542e60eb1",{"id":3118,"createTime":3119,"updateTime":3120,"relativeEntities":3121,"slug":3122,"properties":3123,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"aaf2749c-8e0f-41be-a347-7a5637b5aecd","2024-01-18T06:35:03.110+00:00","2024-10-11T05:52:20.681+00:00",[],"Department-of-Pharmacy-The-Hospital-for-Sick-Children-Toronto-Ontario-Canada",{"title":3124},{"VI":3125},"Department of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada",{"openalex":3127,"orcid":3129,"title":3131},{"VOID":3128},"A5003404145",{"VOID":3130},"https:\u002F\u002Forcid.org\u002F0000-0002-1445-9053",{"EN":3132},"Kathryn Timberlake",{"id":3134,"sortIndex":3135,"researcher":24,"roles":3136,"affiliations":3137,"properties":3144},"5cb3d14b-a03e-4a99-90a5-6dde399609c5",38,[],[3138],{"id":3139,"sortIndex":25,"affiliation":3140,"properties":24},"6ea3a4ab-c37d-49c8-a2a2-ea7fbc80e247",{"id":2502,"createTime":2503,"updateTime":2503,"relativeEntities":3141,"slug":2505,"properties":3142,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3143},{"EN":2508},{"openalex":3145,"orcid":3147,"title":3149},{"VOID":3146},"A5033700485",{"VOID":3148},"https:\u002F\u002Forcid.org\u002F0000-0001-9979-7993",{"EN":3150},"Jason G. Newland",{"id":3152,"sortIndex":376,"researcher":24,"roles":3153,"affiliations":3154,"properties":3161},"fcfbd341-1b8c-424e-a059-f8729bb2c61a",[],[3155],{"id":3156,"sortIndex":25,"affiliation":3157,"properties":24},"130662d7-c2dd-49b6-8b78-8d479c1edbe6",{"id":2544,"createTime":2545,"updateTime":2545,"relativeEntities":3158,"slug":2547,"properties":3159,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3160},{"EN":2550},{"openalex":3162,"orcid":3164,"title":3166},{"VOID":3163},"A5046597535",{"VOID":3165},"https:\u002F\u002Forcid.org\u002F0000-0002-5173-1474",{"EN":3167},"Swetha Pinninti",{"id":3169,"sortIndex":3170,"researcher":24,"roles":3171,"affiliations":3172,"properties":3183},"aa7162ad-10b2-448a-a65e-035e2b5ea0c3",29,[],[3173],{"id":3174,"sortIndex":25,"affiliation":3175,"properties":24},"f181041c-52bb-45bf-99f4-02c69ade6537",{"id":3176,"createTime":3177,"updateTime":3177,"relativeEntities":3178,"slug":3179,"properties":3180,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"112dc8bf-ee6b-4974-80c5-39e633735e3f","2024-10-11T05:52:20.700+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Children-s-Hospital-at-Montefiore-New-York-New-York-USA",{"title":3181},{"EN":3182},"Division of Infectious Diseases, Department of Pediatrics, Children's Hospital at Montefiore, New York, New York, USA",{"openalex":3184,"title":3186},{"VOID":3185},"A5105126100",{"EN":3187},"David L. Goldman",{"id":3189,"sortIndex":3190,"researcher":24,"roles":3191,"affiliations":3192,"properties":3199},"e7297ab8-58c1-485e-af3f-00bc181baf65",35,[],[3193],{"id":3194,"sortIndex":25,"affiliation":3195,"properties":24},"deb1ec43-b056-4a7a-89d0-3a2d5eff1113",{"id":2837,"createTime":2838,"updateTime":2838,"relativeEntities":3196,"slug":2840,"properties":3197,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3198},{"EN":2843},{"openalex":3200,"title":3202},{"VOID":3201},"A5032754610",{"EN":3203},"Emily A. Thorell",{"id":3205,"sortIndex":3206,"researcher":24,"roles":3207,"affiliations":3208,"properties":3219},"a9666a26-bb39-4931-a0cd-6382ad7c1158",26,[],[3209],{"id":3210,"sortIndex":25,"affiliation":3211,"properties":24},"22eec2a6-428b-438d-9ded-1cb88de59c83",{"id":3212,"createTime":3213,"updateTime":3213,"relativeEntities":3214,"slug":3215,"properties":3216,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"fdf95afb-bbf5-4b79-bf2a-8a798c772f24","2024-10-11T05:52:20.621+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Stanford-University-School-of-Medicine-and-Lucile-Packard-Children-s-Hospital-Stanford-Stanford-California-USA",{"title":3217},{"EN":3218},"Division of Infectious Diseases, Department of Pediatrics, Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford, Stanford, California, USA",{"openalex":3220,"orcid":3222,"title":3224},{"VOID":3221},"A5027136615",{"VOID":3223},"https:\u002F\u002Forcid.org\u002F0000-0002-8164-8655",{"EN":3225},"Hayden T. Schwenk",{"id":3227,"sortIndex":272,"researcher":24,"roles":3228,"affiliations":3229,"properties":3240},"111bcd20-a675-48b3-a61b-5a6f6d805a24",[],[3230],{"id":3231,"sortIndex":25,"affiliation":3232,"properties":24},"7d6d1560-27a1-46a5-b001-ddddcfd7df46",{"id":3233,"createTime":3234,"updateTime":3234,"relativeEntities":3235,"slug":3236,"properties":3237,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"2cad34ab-b4d8-4847-a744-b768547d4cde","2024-10-11T05:52:20.855+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-University-of-Colorado-School-of-Medicine-and-Children-s-Hospital-Colorado-Aurora-Colorado-USA",{"title":3238},{"EN":3239},"Division of Infectious Diseases, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA",{"openalex":3241,"orcid":3243,"title":3245},{"VOID":3242},"A5047341084",{"VOID":3244},"https:\u002F\u002Forcid.org\u002F0000-0001-9967-9356",{"EN":3246},"Mark J. Abzug",{"id":3248,"sortIndex":1664,"researcher":24,"roles":3249,"affiliations":3250,"properties":3257},"729fe9d3-69ce-46d1-95c4-3e36efc7c97a",[],[3251],{"id":3252,"sortIndex":25,"affiliation":3253,"properties":24},"0326129e-76a0-4677-bcee-559a01d09514",{"id":3176,"createTime":3177,"updateTime":3177,"relativeEntities":3254,"slug":3179,"properties":3255,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3256},{"EN":3182},{"openalex":3258,"title":3260},{"VOID":3259},"A5072921122",{"EN":3261},"Margaret Aldrich",{"id":3263,"sortIndex":2104,"researcher":24,"roles":3264,"affiliations":3265,"properties":3277},"7cdc8f47-2766-42a9-a634-3403c2f9aeb0",[],[3266],{"id":3267,"sortIndex":25,"affiliation":3268,"properties":24},"e5dba7a5-e115-48f4-a7d1-7b5ce265e345",{"id":3269,"createTime":3270,"updateTime":3271,"relativeEntities":3272,"slug":3273,"properties":3274,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"d6fb586f-3513-4717-913c-f3471d85773f","2024-01-03T05:24:34.728+00:00","2024-10-11T05:52:20.943+00:00",[],"Department-of-Pharmaceutical-Sciences-St-Jude-Children-s-Research-Hospital-Memphis-Tennessee-USA",{"title":3275},{"VI":3276},"Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA",{"openalex":3278,"orcid":3280,"title":3282},{"VOID":3279},"A5053032153",{"VOID":3281},"https:\u002F\u002Forcid.org\u002F0000-0001-7287-6851",{"EN":3283},"Shane J. Cross",{"id":3285,"sortIndex":3286,"researcher":24,"roles":3287,"affiliations":3288,"properties":3295},"b55ba983-abf4-4e39-91ad-9b3773b03cc2",20,[],[3289],{"id":3290,"sortIndex":25,"affiliation":3291,"properties":24},"1e57002e-a056-42c0-a193-a9b4c77ecb19",{"id":2565,"createTime":2566,"updateTime":2566,"relativeEntities":3292,"slug":2568,"properties":3293,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3294},{"EN":2571},{"openalex":3296,"orcid":3298,"title":3300},{"VOID":3297},"A5031607533",{"VOID":3299},"https:\u002F\u002Forcid.org\u002F0000-0001-5015-8146",{"EN":3301},"Kevin J. Downes",{"url":24,"publisher":3303,"properties":3328},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":3304,"slug":10,"properties":3305,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":3311,"manageAffiliations":3312,"indexDatabases":3313,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":3306,"issn":3307,"introduce":3308,"eissn":3309,"title":3310},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[3314,3321],{"id":76,"indexDatabase":3315,"url":91,"indexYears":24,"academicFieldIds":3320,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":3316,"label":3317,"description":3318,"key":87,"publicationTags":3319,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":3322,"url":109,"indexYears":110,"academicFieldIds":3327,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":3323,"label":3324,"description":3325,"key":106,"publicationTags":3326,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":3329,"pages":3331,"issue":3333},{"VOID":3330},"10",{"VOID":3332},"34-48",{"VOID":3334},"1",102,{"total":3335,"publishYear":24,"statisticByYear":3337},{"2020":233,"2021":3019,"2022":2708,"2023":3112,"2024":150},"2021-02-13",2021,[3341,3344,3348,3352,3356,3359,3362,3366,3370,3372,3374,3378,3382,3385,3389,3391,3395,3399,3403,3405,3409,3413,3417,3420,3423,3427,3429,3433,3437,3441,3443,3446,3448,3452,3455,3457,3460,3464,3468,3472,3476,3480,3484,3488,3492,3496,3500,3504,3508,3512,3514,3516,3518,3522,3526,3530,3534,3538,3542,3546,3550,3554,3558,3562,3566,3570,3574,3578,3580,3582,3586,3590,3594,3598,3602,3606,3610,3614,3618,3622,3626,3630,3634,3638,3642,3646,3650,3654,3658,3662,3666,3670,3674,3678,3681,3685,3689,3693,3697,3701,3705,3708,3712,3716,3720,3724,3728,3732,3734,3738,3742,3746,3749,3752,3756,3760,3764,3767,3771,3775,3778,3782,3786,3790,3793,3797,3801,3803,3806,3810,3814,3818,3822],{"id":24,"text":3342,"url":24,"identifiers":3343},"",{},{"id":24,"text":3345,"url":24,"identifiers":3346},"Chiotos, 2020, Multicenter initial guidance on use of antivirals for children with coronavirus disease 2019\u002Fsevere acute respiratory syndrome coronavirus 2, J Pediatr Infect Dis Soc, 10.1093\u002Fjpids\u002Fpiaa045",{"doi":3347},"10.1093\u002Fjpids\u002Fpiaa045",{"id":24,"text":3349,"url":24,"identifiers":3350},"Newland, 2018, (SHARPS): a quality improvement collaborative, J Pediatr Infect Dis Soc, 7, 124, 10.1093\u002Fjpids\u002Fpix020",{"doi":3351},"10.1093\u002Fjpids\u002Fpix020",{"id":24,"text":3353,"url":24,"identifiers":3354},"Beigel, 2020, Remdesivir for the treatment of Covid-19—preliminary report, N Engl J Med, 10.1056\u002FNEJMoa2007764",{"doi":3355},"10.1056\u002FNEJMoa2007764",{"id":24,"text":3357,"url":24,"identifiers":3358},"Horby",{},{"id":24,"text":3360,"url":24,"identifiers":3361},"Tang, 2020, Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial, BMJ, 14",{},{"id":24,"text":3363,"url":24,"identifiers":3364},"Cavalcanti, 2020, Hydroxychloroquine with or without azithromycin in mild-to-moderate Covid-19, N Engl J Med, 10.1056\u002FNEJMoa2019014",{"doi":3365},"10.1056\u002FNEJMoa2019014",{"id":24,"text":3367,"url":24,"identifiers":3368},"Cao, 2020, A Trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19, N Engl J Med, 382, 1787, 10.1056\u002FNEJMoa2001282",{"doi":3369},"10.1056\u002FNEJMoa2001282",{"id":24,"text":3342,"url":24,"identifiers":3371},{},{"id":24,"text":3342,"url":24,"identifiers":3373},{},{"id":24,"text":3375,"url":24,"identifiers":3376},"CDC COVID-19 Response Team, 2020, Coronavirus disease 2019 in children—United States, February 12-April 2, 2020, Morb Mortal Wkly Rep, 69, 422, 10.15585\u002Fmmwr.mm6914e4",{"doi":3377},"10.15585\u002Fmmwr.mm6914e4",{"id":24,"text":3379,"url":24,"identifiers":3380},"Chao, 2020, Clinical characteristics and outcomes of hospitalized and critically ill children and adolescents with coronavirus disease 2019 (COVID-19) at a tertiary care medical center in New York City, J Pediatr, 10.1016\u002Fj.jpeds.2020.05.006",{"doi":3381},"10.1016\u002Fj.jpeds.2020.05.006",{"id":24,"text":3383,"url":24,"identifiers":3384},"Dong, 2020, Epidemiology of COVID-19 among children in China, Pediatrics, 145, e20200702, 10.1542\u002Fpeds.2020-0702",{"doi":1677},{"id":24,"text":3386,"url":24,"identifiers":3387},"Götzinger, 2020, COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study, Lancet Child Adolesc Health, 4, 653, 10.1016\u002FS2352-4642(20)30177-2",{"doi":3388},"10.1016\u002FS2352-4642(20)30177-2",{"id":24,"text":826,"url":24,"identifiers":3390},{"doi":828},{"id":24,"text":3392,"url":24,"identifiers":3393},"Zachariah, 2020, Epidemiology, clinical features, and disease severity in patients with coronavirus disease 2019 (COVID-19) in a children’s hospital in New York City, New York, JAMA Pediatr, 10.1001\u002Fjamapediatrics.2020.2430",{"doi":3394},"10.1001\u002Fjamapediatrics.2020.2430",{"id":24,"text":3396,"url":24,"identifiers":3397},"Parri, 2020, Characteristic of COVID-19 infection in pediatric patients: early findings from two Italian pediatric research networks, Eur J Pediatr, 179, 1315, 10.1007\u002Fs00431-020-03683-8",{"doi":3398},"10.1007\u002Fs00431-020-03683-8",{"id":24,"text":3400,"url":24,"identifiers":3401},"Otto, 2020, The epidemiology of SARS-CoV-2 in a pediatric healthcare network in the United States, J Pediatr Infect Dis Soc, 10.1093\u002Fjpids\u002Fpiaa074",{"doi":3402},"10.1093\u002Fjpids\u002Fpiaa074",{"id":24,"text":3342,"url":24,"identifiers":3404},{},{"id":24,"text":3406,"url":24,"identifiers":3407},"Zimmermann, 2020, Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children, Pediatr Infect Dis J, 39, 355, 10.1097\u002FINF.0000000000002660",{"doi":3408},"10.1097\u002FINF.0000000000002660",{"id":24,"text":3410,"url":24,"identifiers":3411},"Kim, 2020, Hospitalization rates and characteristics of children aged <18 years hospitalized with laboratory-confirmed COVID-19—COVID-NET, 14 states, March 1–July 25, 2020, Morb Mortal Wkly Rep, 69, 1081, 10.15585\u002Fmmwr.mm6932e3",{"doi":3412},"10.15585\u002Fmmwr.mm6932e3",{"id":24,"text":3414,"url":24,"identifiers":3415},"Bialek, 2020, Severe outcomes among patients with coronavirus disease 2019 (COVID-19)—United States, February 12–March 16, 2020, Morb Mortal Wkly Rep, 69, 343, 10.15585\u002Fmmwr.mm6912e2",{"doi":3416},"10.15585\u002Fmmwr.mm6912e2",{"id":24,"text":3418,"url":24,"identifiers":3419},"DeBiasi, 2020, Severe COVID-19 in children and young adults in the Washington, DC metropolitan region, J Pediatr",{},{"id":24,"text":3421,"url":24,"identifiers":3422},"Derespina, 2020, Clinical manifestations and outcomes of critically Ill children and adolescents with COVID-19 in New York City, J Pediatr",{},{"id":24,"text":3424,"url":24,"identifiers":3425},"Dufort, 2020, Multisystem inflammatory syndrome in children in New York State, N Engl J Med, 383, 347, 10.1056\u002FNEJMoa2021756",{"doi":3426},"10.1056\u002FNEJMoa2021756",{"id":24,"text":830,"url":24,"identifiers":3428},{"doi":832},{"id":24,"text":3430,"url":24,"identifiers":3431},"Toubiana, 2020, Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study, BMJ, 369, m2094, 10.1136\u002Fbmj.m2094",{"doi":3432},"10.1136\u002Fbmj.m2094",{"id":24,"text":3434,"url":24,"identifiers":3435},"Verdoni, 2020, An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study, Lancet, 395, 1771, 10.1016\u002FS0140-6736(20)31103-X",{"doi":3436},"10.1016\u002FS0140-6736(20)31103-X",{"id":24,"text":3438,"url":24,"identifiers":3439},"Whittaker, 2020, Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2, JAMA, 324, 259, 10.1001\u002Fjama.2020.10369",{"doi":3440},"10.1001\u002Fjama.2020.10369",{"id":24,"text":1672,"url":24,"identifiers":3442},{},{"id":24,"text":3444,"url":24,"identifiers":3445},"World Health Organization",{},{"id":24,"text":3342,"url":24,"identifiers":3447},{},{"id":24,"text":3449,"url":24,"identifiers":3450},"Levin, 2020, Childhood multisystem inflammatory syndrome—a new challenge in the pandemic, N Engl J Med, 383, 393, 10.1056\u002FNEJMe2023158",{"doi":3451},"10.1056\u002FNEJMe2023158",{"id":24,"text":3453,"url":24,"identifiers":3454},"Bhimraj",{},{"id":24,"text":3342,"url":24,"identifiers":3456},{},{"id":24,"text":3458,"url":24,"identifiers":3459},"Dulek, 2020, Multidisciplinary guidance regarding the use of immunomodulatory therapies for acute COVID-19 in pediatric patients, J Pediatr Infect Dis Soc",{},{"id":24,"text":3461,"url":24,"identifiers":3462},"Xia, 2020, Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults, Pediatr Pulmonol, 55, 1169, 10.1002\u002Fppul.24718",{"doi":3463},"10.1002\u002Fppul.24718",{"id":24,"text":3465,"url":24,"identifiers":3466},"Gao, 2020, Structure of the RNA-dependent RNA polymerase from COVID-19 virus, Science, 368, 779, 10.1126\u002Fscience.abb7498",{"doi":3467},"10.1126\u002Fscience.abb7498",{"id":24,"text":3469,"url":24,"identifiers":3470},"Yin, 2020, Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir, Science, 368, 1499, 10.1126\u002Fscience.abc1560",{"doi":3471},"10.1126\u002Fscience.abc1560",{"id":24,"text":3473,"url":24,"identifiers":3474},"Agostini, 2018, Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease, mBio, 9, e00221-18, 10.1128\u002FmBio.00221-18",{"doi":3475},"10.1128\u002FmBio.00221-18",{"id":24,"text":3477,"url":24,"identifiers":3478},"Smith, 2013, Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics, PLoS Pathog, 9, e1003565, 10.1371\u002Fjournal.ppat.1003565",{"doi":3479},"10.1371\u002Fjournal.ppat.1003565",{"id":24,"text":3481,"url":24,"identifiers":3482},"Wang, 2020, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro, Cell Res, 30, 269, 10.1038\u002Fs41422-020-0282-0",{"doi":3483},"10.1038\u002Fs41422-020-0282-0",{"id":24,"text":3485,"url":24,"identifiers":3486},"Goldman, 2020, Remdesivir for 5 or 10 days in patients with severe covid-19, N Engl J Med, 10.1056\u002FNEJMoa2015301",{"doi":3487},"10.1056\u002FNEJMoa2015301",{"id":24,"text":3489,"url":24,"identifiers":3490},"Spinner, 2020, Effect of remdesivir vs standard care on clinical status at 11 days in patients with moderate COVID-19: a randomized clinical trial, JAMA, 10.1001\u002Fjama.2020.16349",{"doi":3491},"10.1001\u002Fjama.2020.16349",{"id":24,"text":3493,"url":24,"identifiers":3494},"Wang, 2020, Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial, Lancet, 395, 1569, 10.1016\u002FS0140-6736(20)31022-9",{"doi":3495},"10.1016\u002FS0140-6736(20)31022-9",{"id":24,"text":3497,"url":24,"identifiers":3498},"Dubert, 2020, Case report study of the first five COVID-19 patients treated with remdesivir in France, Int J Infect Dis, 98, 290, 10.1016\u002Fj.ijid.2020.06.093",{"doi":3499},"10.1016\u002Fj.ijid.2020.06.093",{"id":24,"text":3501,"url":24,"identifiers":3502},"Grein, 2020, Compassionate use of remdesivir for patients with severe covid-19, N Engl J Med, 382, 2327, 10.1056\u002FNEJMoa2007016",{"doi":3503},"10.1056\u002FNEJMoa2007016",{"id":24,"text":3505,"url":24,"identifiers":3506},"Holshue, 2020, First case of 2019 novel coronavirus in the United States, N Engl J Med, 382, 929, 10.1056\u002FNEJMoa2001191",{"doi":3507},"10.1056\u002FNEJMoa2001191",{"id":24,"text":3509,"url":24,"identifiers":3510},"Mulangu, 2019, A randomized, controlled trial of Ebola virus disease therapeutics, N Engl J Med, 381, 2293, 10.1056\u002FNEJMoa1910993",{"doi":3511},"10.1056\u002FNEJMoa1910993",{"id":24,"text":3342,"url":24,"identifiers":3513},{},{"id":24,"text":3342,"url":24,"identifiers":3515},{},{"id":24,"text":3342,"url":24,"identifiers":3517},{},{"id":24,"text":3519,"url":24,"identifiers":3520},"Godfred-Cato, 2020, COVID-19–associated multisystem inflammatory syndrome in children—United States, March–July 2020, Morb Mortal Wkly Rep, 69, 1074, 10.15585\u002Fmmwr.mm6932e2",{"doi":3521},"10.15585\u002Fmmwr.mm6932e2",{"id":24,"text":3523,"url":24,"identifiers":3524},"Cohen, 2011, Children with medical complexity: an emerging population for clinical and research initiatives, Pediatrics, 127, 529, 10.1542\u002Fpeds.2010-0910",{"doi":3525},"10.1542\u002Fpeds.2010-0910",{"id":24,"text":3527,"url":24,"identifiers":3528},"Leyenaar, 2014, Management and outcomes of pneumonia among children with complex chronic conditions, Pediatr Infect Dis J, 33, 907, 10.1097\u002FINF.0000000000000317",{"doi":3529},"10.1097\u002FINF.0000000000000317",{"id":24,"text":3531,"url":24,"identifiers":3532},"Kuo, 2011, A national profile of caregiver challenges among more medically complex children with special health care needs, Arch Pediatr Adolesc Med, 165, 1020, 10.1001\u002Farchpediatrics.2011.172",{"doi":3533},"10.1001\u002Farchpediatrics.2011.172",{"id":24,"text":3535,"url":24,"identifiers":3536},"Wei, 2020, Novel coronavirus infection in hospitalized infants under 1 year of age in China, JAMA, 323, 1313, 10.1001\u002Fjama.2020.2131",{"doi":3537},"10.1001\u002Fjama.2020.2131",{"id":24,"text":3539,"url":24,"identifiers":3540},"Xu, 2020, Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding, Nat Med, 26, 502, 10.1038\u002Fs41591-020-0817-4",{"doi":3541},"10.1038\u002Fs41591-020-0817-4",{"id":24,"text":3543,"url":24,"identifiers":3544},"Mithal, 2020, SARS-CoV-2 infection in infants less than 90 days old, J Pediatr, 224, 150, 10.1016\u002Fj.jpeds.2020.06.047",{"doi":3545},"10.1016\u002Fj.jpeds.2020.06.047",{"id":24,"text":3547,"url":24,"identifiers":3548},"Bisogno, 2020, Clinical characteristics and outcome of SARS-CoV-2 infection in Italian pediatric oncology patients: a study from the Infectious Diseases Working Group of the AIEOP, J Pediatr Infect Dis Soc, 10.1093\u002Fjpids\u002Fpiaa088",{"doi":3549},"10.1093\u002Fjpids\u002Fpiaa088",{"id":24,"text":3551,"url":24,"identifiers":3552},"Boulad, 2020, COVID-19 in children with cancer in New York City, JAMA Oncol, 10.1001\u002Fjamaoncol.2020.2028",{"doi":3553},"10.1001\u002Fjamaoncol.2020.2028",{"id":24,"text":3555,"url":24,"identifiers":3556},"de Rojas, 2020, COVID-19 infection in children and adolescents with cancer in Madrid, Pediatr Blood Cancer, 67, e28397, 10.1002\u002Fpbc.28397",{"doi":3557},"10.1002\u002Fpbc.28397",{"id":24,"text":3559,"url":24,"identifiers":3560},"Hrusak, 2020, Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment, Eur J Cancer, 132, 11, 10.1016\u002Fj.ejca.2020.03.021",{"doi":3561},"10.1016\u002Fj.ejca.2020.03.021",{"id":24,"text":3563,"url":24,"identifiers":3564},"Heinz, 2020, A case of an infant with SARS-CoV-2 hepatitis early after liver transplantation [published online ahead of print June 25, 2020], Pediatr Transplant, e13778, 10.1111\u002Fpetr.13778",{"doi":3565},"10.1111\u002Fpetr.13778",{"id":24,"text":3567,"url":24,"identifiers":3568},"Morand, 2020, Child with liver transplant recovers from COVID-19 infection. A case report, Arch Pediatr, 27, 275, 10.1016\u002Fj.arcped.2020.05.004",{"doi":3569},"10.1016\u002Fj.arcped.2020.05.004",{"id":24,"text":3571,"url":24,"identifiers":3572},"Nicastro, 2020, Impact of the SARS-CoV-2 outbreak on pediatric liver transplant recipients residing in Lombardy, Northern Italy, Liver Transplant, 10.1002\u002Flt.25840",{"doi":3573},"10.1002\u002Flt.25840",{"id":24,"text":3575,"url":24,"identifiers":3576},"Russell, 2020, COVID-19 in a pediatric heart transplant recipient: emergence of donor-specific antibodies, J Heart Lung Transplant, 39, 732, 10.1016\u002Fj.healun.2020.04.021",{"doi":3577},"10.1016\u002Fj.healun.2020.04.021",{"id":24,"text":3342,"url":24,"identifiers":3579},{},{"id":24,"text":3342,"url":24,"identifiers":3581},{},{"id":24,"text":3583,"url":24,"identifiers":3584},"Kuderer, 2020, Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study, Lancet, 395, 1907, 10.1016\u002FS0140-6736(20)31187-9",{"doi":3585},"10.1016\u002FS0140-6736(20)31187-9",{"id":24,"text":3587,"url":24,"identifiers":3588},"Lee, 2020, COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study, Lancet, 395, 1919, 10.1016\u002FS0140-6736(20)31173-9",{"doi":3589},"10.1016\u002FS0140-6736(20)31173-9",{"id":24,"text":3591,"url":24,"identifiers":3592},"Zhang, 2020, Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China, Ann Oncol, 31, 894, 10.1016\u002Fj.annonc.2020.03.296",{"doi":3593},"10.1016\u002Fj.annonc.2020.03.296",{"id":24,"text":3595,"url":24,"identifiers":3596},"Ogimi, 2019, Characteristics and outcomes of coronavirus infection in children: the role of viral factors and an immunocompromised state, J Pediatric Infect Dis Soc, 8, 21, 10.1093\u002Fjpids\u002Fpix093",{"doi":3597},"10.1093\u002Fjpids\u002Fpix093",{"id":24,"text":3599,"url":24,"identifiers":3600},"Fisher, 2018, A multicenter consortium to define the epidemiology and outcomes of inpatient respiratory viral infections in pediatric hematopoietic stem cell transplant recipients, J Pediatric Infect Dis Soc, 7, 275, 10.1093\u002Fjpids\u002Fpix051",{"doi":3601},"10.1093\u002Fjpids\u002Fpix051",{"id":24,"text":3603,"url":24,"identifiers":3604},"Kim, 2014, Respiratory syncytial virus in hematopoietic cell transplant recipients: factors determining progression to lower respiratory tract disease, J Infect Dis, 209, 1195, 10.1093\u002Finfdis\u002Fjit832",{"doi":3605},"10.1093\u002Finfdis\u002Fjit832",{"id":24,"text":3607,"url":24,"identifiers":3608},"Shah, 2014, Immunodeficiency scoring index to predict poor outcomes in hematopoietic cell transplant recipients with RSV infections, Blood, 123, 3263, 10.1182\u002Fblood-2013-12-541359",{"doi":3609},"10.1182\u002Fblood-2013-12-541359",{"id":24,"text":3611,"url":24,"identifiers":3612},"Chemaly, 2020, Cytomegalovirus (CMV) cell-mediated immunity and CMV infection after allogeneic hematopoietic cell transplantation: the REACT study, Clin Infect Dis, 10.1093\u002Fcid\u002Fciz1210",{"doi":3613},"10.1093\u002Fcid\u002Fciz1210",{"id":24,"text":3615,"url":24,"identifiers":3616},"Seo, 2014, Parainfluenza virus lower respiratory tract disease after hematopoietic cell transplant: viral detection in the lung predicts outcome, Clin Infect Dis, 58, 1357, 10.1093\u002Fcid\u002Fciu134",{"doi":3617},"10.1093\u002Fcid\u002Fciu134",{"id":24,"text":3619,"url":24,"identifiers":3620},"Waghmare, 2013, Respiratory syncytial virus lower respiratory disease in hematopoietic cell transplant recipients: viral RNA detection in blood, antiviral treatment, and clinical outcomes, Clin Infect Dis, 57, 1731, 10.1093\u002Fcid\u002Fcit639",{"doi":3621},"10.1093\u002Fcid\u002Fcit639",{"id":24,"text":3623,"url":24,"identifiers":3624},"Stokes, 2020, Coronavirus disease 2019 case surveillance—United States, January 22-May 30, 2020, Morb Mortal Wkly Rep, 69, 759, 10.15585\u002Fmmwr.mm6924e2",{"doi":3625},"10.15585\u002Fmmwr.mm6924e2",{"id":24,"text":3627,"url":24,"identifiers":3628},"Wang, 2020, Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China, JAMA, 1061, 10.1001\u002Fjama.2020.1585",{"doi":3629},"10.1001\u002Fjama.2020.1585",{"id":24,"text":3631,"url":24,"identifiers":3632},"Wang, 2020, Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures, J Med Virol, 92, 568, 10.1002\u002Fjmv.25748",{"doi":3633},"10.1002\u002Fjmv.25748",{"id":24,"text":3635,"url":24,"identifiers":3636},"Yang, 2020, Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis, Int J Infect Dis, 94, 91, 10.1016\u002Fj.ijid.2020.03.017",{"doi":3637},"10.1016\u002Fj.ijid.2020.03.017",{"id":24,"text":3639,"url":24,"identifiers":3640},"Zhou, 2020, Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study, Lancet, 395, 1054, 10.1016\u002FS0140-6736(20)30566-3",{"doi":3641},"10.1016\u002FS0140-6736(20)30566-3",{"id":24,"text":3643,"url":24,"identifiers":3644},"Alsaied, 2020, Coronavirus disease 2019 (COVID-19) pandemic implications in pediatric and adult congenital heart disease, J Am Heart Assoc, 9, e017224, 10.1161\u002FJAHA.120.017224",{"doi":3645},"10.1161\u002FJAHA.120.017224",{"id":24,"text":3647,"url":24,"identifiers":3648},"Chaves, 2014, The burden of influenza hospitalizations in infants from 2003 to 2012, United States, Pediatr Infect Dis J, 33, 912, 10.1097\u002FINF.0000000000000321",{"doi":3649},"10.1097\u002FINF.0000000000000321",{"id":24,"text":3651,"url":24,"identifiers":3652},"Tuckerman, 2019, Influenza in children with special risk medical conditions: a systematic review and meta-analysis, Pediatr Infect Dis J, 38, 912, 10.1097\u002FINF.0000000000002405",{"doi":3653},"10.1097\u002FINF.0000000000002405",{"id":24,"text":3655,"url":24,"identifiers":3656},"Slavin, 2000, Parainfluenza virus type 4: case report and review of the literature, Pediatr Infect Dis J, 19, 893, 10.1097\u002F00006454-200009000-00020",{"doi":3657},"10.1097\u002F00006454-200009000-00020",{"id":24,"text":3659,"url":24,"identifiers":3660},"Boyce, 2000, Rates of hospitalization for respiratory syncytial virus infection among children in Medicaid, J Pediatr, 137, 865, 10.1067\u002Fmpd.2000.110531",{"doi":3661},"10.1067\u002Fmpd.2000.110531",{"id":24,"text":3663,"url":24,"identifiers":3664},"Hall, 2009, The burden of respiratory syncytial virus infection in young children, N Engl J Med, 360, 588, 10.1056\u002FNEJMoa0804877",{"doi":3665},"10.1056\u002FNEJMoa0804877",{"id":24,"text":3667,"url":24,"identifiers":3668},"Wang, 1996, Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study of admission and management variation in patients hospitalized with respiratory syncytial viral lower respiratory tract infection, J Pediatr, 129, 390, 10.1016\u002FS0022-3476(96)70071-9",{"doi":3669},"10.1016\u002FS0022-3476(96)70071-9",{"id":24,"text":3671,"url":24,"identifiers":3672},"Welliver, 2010, Fatality rates in published reports of RSV hospitalizations among high-risk and otherwise healthy children, Curr Med Res Opin, 26, 2175, 10.1185\u002F03007995.2010.505126",{"doi":3673},"10.1185\u002F03007995.2010.505126",{"id":24,"text":3675,"url":24,"identifiers":3676},"da Silva Filho, 2012, The differential clinical impact of human coronavirus species in children with cystic fibrosis, J Infect Dis, 206, 384, 10.1093\u002Finfdis\u002Fjis274",{"doi":3677},"10.1093\u002Finfdis\u002Fjis274",{"id":24,"text":3679,"url":24,"identifiers":3680},"Stout, 2019, 2018 AHA\u002FACC guideline for the management of adults with congenital heart disease: executive summary: a report of the American College of Cardiology\u002FAmerican Heart Association Task Force on Clinical Practice Guidelines, Circulation, 139",{},{"id":24,"text":3682,"url":24,"identifiers":3683},"McMichael, 2020, COVID-19 in a long-term care facility—King County, Washington, February 27–March 9, 2020, Morb Mortal Wkly Rep, 69, 339, 10.15585\u002Fmmwr.mm6912e1",{"doi":3684},"10.15585\u002Fmmwr.mm6912e1",{"id":24,"text":3686,"url":24,"identifiers":3687},"Lighter, 2020, Obesity in patients younger than 60 years is a risk factor for COVID-19 hospital admission, Clin Infect Dis, 71, 896, 10.1093\u002Fcid\u002Fciaa415",{"doi":3688},"10.1093\u002Fcid\u002Fciaa415",{"id":24,"text":3690,"url":24,"identifiers":3691},"Kass, 2020, Obesity could shift severe COVID-19 disease to younger ages, Lancet, 395, 1544, 10.1016\u002FS0140-6736(20)31024-2",{"doi":3692},"10.1016\u002FS0140-6736(20)31024-2",{"id":24,"text":3694,"url":24,"identifiers":3695},"Kalligeros, 2020, Association of obesity with disease severity among patients with coronavirus disease 2019, Obesity, 28, 1200, 10.1002\u002Foby.22859",{"doi":3696},"10.1002\u002Foby.22859",{"id":24,"text":3698,"url":24,"identifiers":3699},"Huang, 2020, Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center study, PLoS Negl Trop Dis, 14, e0008280, 10.1371\u002Fjournal.pntd.0008280",{"doi":3700},"10.1371\u002Fjournal.pntd.0008280",{"id":24,"text":3702,"url":24,"identifiers":3703},"Cai, 2020, Obesity and COVID-19 severity in a designated hospital in Shenzhen, China, Diabetes Care, 43, 1392, 10.2337\u002Fdc20-0576",{"doi":3704},"10.2337\u002Fdc20-0576",{"id":24,"text":3706,"url":24,"identifiers":3707},"Ogden, 2018, Prevalence of obesity among youths by household income and education level of head of household—United States 2011–2014, Morb Mortal Wkly Rep, 67",{},{"id":24,"text":3709,"url":24,"identifiers":3710},"Guan, 2020, Clinical characteristics of coronavirus disease 2019 in China, N Engl J Med, 382, 1708, 10.1056\u002FNEJMoa2002032",{"doi":3711},"10.1056\u002FNEJMoa2002032",{"id":24,"text":3713,"url":24,"identifiers":3714},"Petrilli, 2020, Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study, BMJ, 369, m1966, 10.1136\u002Fbmj.m1966",{"doi":3715},"10.1136\u002Fbmj.m1966",{"id":24,"text":3717,"url":24,"identifiers":3718},"Wu, 2020, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China, JAMA Intern Med, 180, 934, 10.1001\u002Fjamainternmed.2020.0994",{"doi":3719},"10.1001\u002Fjamainternmed.2020.0994",{"id":24,"text":3721,"url":24,"identifiers":3722},"SEARCH for Diabetes in Youth Study Group, 2006, The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth study, Pediatrics, 118, 1510, 10.1542\u002Fpeds.2006-0690",{"doi":3723},"10.1542\u002Fpeds.2006-0690",{"id":24,"text":3725,"url":24,"identifiers":3726},"Vaduganathan, 2020, Renin-angiotensin-aldosterone system inhibitors in patients with Covid-19, N Engl J Med, 382, 1653, 10.1056\u002FNEJMsr2005760",{"doi":3727},"10.1056\u002FNEJMsr2005760",{"id":24,"text":3729,"url":24,"identifiers":3730},"Al-Bari, 2015, Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases, J Antimicrob Chemother, 70, 1608, 10.1093\u002Fjac\u002Fdkv018",{"doi":3731},"10.1093\u002Fjac\u002Fdkv018",{"id":24,"text":3342,"url":24,"identifiers":3733},{},{"id":24,"text":3735,"url":24,"identifiers":3736},"Gautret, 2020, Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial, Int J Antimicrob Agents, 56, 105949, 10.1016\u002Fj.ijantimicag.2020.105949",{"doi":3737},"10.1016\u002Fj.ijantimicag.2020.105949",{"id":24,"text":3739,"url":24,"identifiers":3740},"Gautret, 2020, Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: a pilot observational study, Travel Med Infect Dis, 34, 101663, 10.1016\u002Fj.tmaid.2020.101663",{"doi":3741},"10.1016\u002Fj.tmaid.2020.101663",{"id":24,"text":3743,"url":24,"identifiers":3744},"Molina, 2020, No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection, Med Mal Infect, 50, 384, 10.1016\u002Fj.medmal.2020.03.006",{"doi":3745},"10.1016\u002Fj.medmal.2020.03.006",{"id":24,"text":3747,"url":24,"identifiers":3748},"Chen",{},{"id":24,"text":3750,"url":24,"identifiers":3751},"Chen, 2020, A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19, J Zhejiang Univ Med Sci, 49, 215",{},{"id":24,"text":3753,"url":24,"identifiers":3754},"Boulware, 2020, A randomized trial of hydroxychloroquine as postexposure prophylaxis for Covid-19, N Engl J Med, 383, 517, 10.1056\u002FNEJMoa2016638",{"doi":3755},"10.1056\u002FNEJMoa2016638",{"id":24,"text":3757,"url":24,"identifiers":3758},"Mahévas, 2020, Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data, BMJ, 369, m1844, 10.1136\u002Fbmj.m1844",{"doi":3759},"10.1136\u002Fbmj.m1844",{"id":24,"text":3761,"url":24,"identifiers":3762},"Geleris, 2020, Observational study of hydroxychloroquine in hospitalized patients with Covid-19, N Engl J Med, 382, 2411, 10.1056\u002FNEJMoa2012410",{"doi":3763},"10.1056\u002FNEJMoa2012410",{"id":24,"text":3765,"url":24,"identifiers":3766},"Magagnoli, 2020, Outcomes of hydroxychloroquine usage in United States veterans hospitalized with COVID-19, Med(NY)",{},{"id":24,"text":3768,"url":24,"identifiers":3769},"Rosenberg, 2020, Association of treatment with hydroxychloroquine or azithromycin with in-hospital mortality in patients with COVID-19 in New York State, JAMA, 323, 2493, 10.1001\u002Fjama.2020.8630",{"doi":3770},"10.1001\u002Fjama.2020.8630",{"id":24,"text":3772,"url":24,"identifiers":3773},"Arshad, 2020, Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19, Int J Infect Dis, 97, 396, 10.1016\u002Fj.ijid.2020.06.099",{"doi":3774},"10.1016\u002Fj.ijid.2020.06.099",{"id":24,"text":3776,"url":24,"identifiers":3777},"Chorin, 2020, QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine\u002Fazithromycin, Heart Rhythm, 1424",{},{"id":24,"text":3779,"url":24,"identifiers":3780},"Mercuro, 2020, Risk of QT interval prolongation associated with use of hydroxychloroquine with or without concomitant azithromycin among hospitalized patients testing positive for coronavirus disease 2019 (COVID-19), JAMA Cardiol, 10.1001\u002Fjamacardio.2020.1834",{"doi":3781},"10.1001\u002Fjamacardio.2020.1834",{"id":24,"text":3783,"url":24,"identifiers":3784},"Borba, 2020, Effect of high vs low doses of chloroquine diphosphate as adjunctive therapy for patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a randomized clinical trial, JAMA Netw Open, 3, e208857, 10.1001\u002Fjamanetworkopen.2020.8857",{"doi":3785},"10.1001\u002Fjamanetworkopen.2020.8857",{"id":24,"text":3787,"url":24,"identifiers":3788},"Verscheijden, 2020, Chloroquine dosing recommendations for pediatric COVID-19 supported by modeling and simulation, Clin Pharmacol Ther, 108, 248, 10.1002\u002Fcpt.1864",{"doi":3789},"10.1002\u002Fcpt.1864",{"id":24,"text":3791,"url":24,"identifiers":3792},"Guidelines for the use of antiretroviral agents in pediatric HIV infection Lopinavir\u002FRitonavir Protease Inhibitors (PIs)",{},{"id":24,"text":3794,"url":24,"identifiers":3795},"Lopez-Cortes, 2013, Lopinavir plasma concentrations and virological outcome with lopinavir-ritonavir monotherapy in HIV-1-infected patients, Antimicrob Agents Chemother, 57, 3746, 10.1128\u002FAAC.00315-13",{"doi":3796},"10.1128\u002FAAC.00315-13",{"id":24,"text":3798,"url":24,"identifiers":3799},"Choy, 2020, Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro, Antiviral Res, 178, 104786, 10.1016\u002Fj.antiviral.2020.104786",{"doi":3800},"10.1016\u002Fj.antiviral.2020.104786",{"id":24,"text":3342,"url":24,"identifiers":3802},{},{"id":24,"text":3804,"url":24,"identifiers":3805},"Li",{},{"id":24,"text":3807,"url":24,"identifiers":3808},"Chen, 2020, Antiviral activity and safety of darunavir\u002Fcobicistat for the treatment of COVID-19, Open Forum Infect Dis, 7, ofaa241, 10.1093\u002Fofid\u002Fofaa241",{"doi":3809},"10.1093\u002Fofid\u002Fofaa241",{"id":24,"text":3811,"url":24,"identifiers":3812},"Lecronier, 2020, Comparison of hydroxychloroquine, lopinavir\u002Fritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis, Crit Care, 24, 418, 10.1186\u002Fs13054-020-03117-9",{"doi":3813},"10.1186\u002Fs13054-020-03117-9",{"id":24,"text":3815,"url":24,"identifiers":3816},"Stader, 2020, Stopping lopinavir\u002Fritonavir in COVID-19 patients: duration of the drug interacting effect, J Antimicrob Chemother, 10.1093\u002Fjac\u002Fdkaa253",{"doi":3817},"10.1093\u002Fjac\u002Fdkaa253",{"id":24,"text":3819,"url":24,"identifiers":3820},"Choi, 2020, Clinical characteristics and disease progression in early-stage COVID-19 patients in South Korea, J Clin Med, 9, 1959, 10.3390\u002Fjcm9061959",{"doi":3821},"10.3390\u002Fjcm9061959",{"id":24,"text":3823,"url":24,"identifiers":3824},"Qiu, 2020, Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study, Lancet Infect Dis, 20, 689, 10.1016\u002FS1473-3099(20)30198-5",{"doi":3825},"10.1016\u002FS1473-3099(20)30198-5",{"id":3827,"createTime":3828,"updateTime":3828,"relativeEntities":3829,"slug":3830,"properties":3831,"entityType":141,"verifyStatus":142,"verifyTime":3828,"verifyNote":143,"syncStatus":23,"languages":3847,"translateLanguages":24,"viewCount":25,"primaryUrl":3848,"fullTextUrl":24,"authors":3849,"publicationType":398,"publisherRelationship":4188,"citationCount":4220,"citationInfo":4221,"publishDate":4223,"publishYear":439,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":4224,"isForceReanalyzing":462},"9413bd3f-1a51-446f-8421-8e61a5db2eee","2024-10-11T05:52:15.324+00:00",[],"Multidisciplinary-Guidance-Regarding-the-Use-of-Immunomodulatory-Therapies-for-Acute-Coronavirus-Disease-2019-in-Pediatric-Patients",{"mag":3832,"keywords":3834,"pmc":3835,"openalex":3837,"abstract":3839,"title":3841,"pm":3843,"doi":3845},{"VOID":3833},"3049581053",{},{"VOID":3836},"7454742",{"VOID":3838},"W3049581053",{"EN":3840},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\u003Cjats:sec>\u003Cjats:title>Background\u003C\u002Fjats:title>\u003Cjats:p>Immune-mediated lung injury and systemic hyperinflammation are characteristic of severe and critical coronavirus disease 2019 (COVID-19) in adults. Although the majority of severe acute respiratory syndrome coronavirus 2 infections in pediatric populations result in minimal or mild COVID-19 in the acute phase of infection, a small subset of children develop severe and even critical disease in this phase with concomitant inflammation that may benefit from immunomodulation. Therefore, guidance is needed regarding immunomodulatory therapies in the setting of acute pediatric COVID-19. This document does not provide guidance regarding the recently emergent multisystem inflammatory syndrome in children (MIS-C).\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Methods\u003C\u002Fjats:title>\u003Cjats:p>A multidisciplinary panel of pediatric subspecialty physicians and pharmacists with expertise in infectious diseases, rheumatology, hematology\u002Foncology, and critical care medicine was convened. Guidance statements were developed based on best available evidence and expert opinion.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Results\u003C\u002Fjats:title>\u003Cjats:p>The panel devised a framework for considering the use of immunomodulatory therapy based on an assessment of clinical disease severity and degree of multiorgan involvement combined with evidence of hyperinflammation. Additionally, the known rationale for consideration of each immunomodulatory approach and the associated risks and benefits was summarized.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>\u003Cjats:sec>\u003Cjats:title>Conclusions\u003C\u002Fjats:title>\u003Cjats:p>Immunomodulatory therapy is not recommended for the majority of pediatric patients, who typically develop mild or moderate COVID-19. For children with severe or critical illness, the use of immunomodulatory agents may be beneficial. The risks and benefits of such therapies are variable and should be evaluated on a case-by-case basis with input from appropriate specialty services. When available, the panel strongly favors immunomodulatory agent use within the context of clinical trials. The framework presented herein offers an approach to decision-making regarding immunomodulatory therapy for severe or critical pediatric COVID-19 and is informed by currently available data, while awaiting results of placebo-controlled randomized clinical trials.\u003C\u002Fjats:p>\u003C\u002Fjats:sec>",{"EN":3842},"Multidisciplinary Guidance Regarding the Use of Immunomodulatory Therapies for Acute Coronavirus Disease 2019 in Pediatric Patients",{"VOID":3844},"32808988",{"VOID":3846},"10.1093\u002Fjpids\u002Fpiaa098",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F9\u002F6\u002F716\u002F5893843",[3850,3868,3882,3903,3924,3943,3962,3983,4004,4026,4044,4065,4084,4112,4134,4148,4169],{"id":3851,"sortIndex":581,"researcher":24,"roles":3852,"affiliations":3853,"properties":3864},"4c2f116f-41a4-4dad-9ae4-a14d479c990b",[],[3854],{"id":3855,"sortIndex":25,"affiliation":3856,"properties":24},"a190ad7c-e4dc-4bc0-8281-bbb77dba7aa6",{"id":3857,"createTime":3858,"updateTime":3858,"relativeEntities":3859,"slug":3860,"properties":3861,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"95c436bc-ce17-4d17-abfe-d57eb934feb0","2024-10-11T05:52:15.364+00:00",[],"Division-of-Pediatric-Rheumatology-Department-of-Pediatrics-Children-s-Hospital-of-Philadelphia-University-of-Pennsylvania-Perelman-School-of-Medicine-Philadelphia-Pennsylvania-USA",{"title":3862},{"EN":3863},"Division of Pediatric Rheumatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA",{"openalex":3865,"orcid":3866,"title":3867},{"VOID":1599},{"VOID":1601},{"EN":1603},{"id":3869,"sortIndex":508,"researcher":24,"roles":3870,"affiliations":3871,"properties":3878},"a4e64a57-d8d9-4c61-a157-58c68e62f47f",[],[3872],{"id":3873,"sortIndex":25,"affiliation":3874,"properties":24},"f2906be3-6efb-4c38-b7fb-ee6965d6b7e2",{"id":2982,"createTime":2983,"updateTime":2983,"relativeEntities":3875,"slug":2985,"properties":3876,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":3877},{"EN":2988},{"openalex":3879,"orcid":3880,"title":3881},{"VOID":2991},{"VOID":2993},{"EN":2995},{"id":3883,"sortIndex":792,"researcher":24,"roles":3884,"affiliations":3885,"properties":3896},"41640b47-3ad4-45cf-99f1-e1839d4f4ca7",[],[3886],{"id":3887,"sortIndex":25,"affiliation":3888,"properties":24},"93b5164b-f888-4e77-b1a5-a9d499581a53",{"id":3889,"createTime":3890,"updateTime":3890,"relativeEntities":3891,"slug":3892,"properties":3893,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"6d2e0631-aec6-45cd-897c-879b52dab914","2024-10-11T05:52:15.484+00:00",[],"Division-of-Pediatric-Rheumatology-Department-of-Pediatrics-University-of-Alabama-at-Birmingham-School-of-Medicine-Birmingham-Alabama-USA",{"title":3894},{"EN":3895},"Division of Pediatric Rheumatology, Department of Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA",{"openalex":3897,"orcid":3899,"title":3901},{"VOID":3898},"A5034036024",{"VOID":3900},"https:\u002F\u002Forcid.org\u002F0000-0003-2661-3086",{"EN":3902},"Randy Q. Cron",{"id":3904,"sortIndex":620,"researcher":24,"roles":3905,"affiliations":3906,"properties":3917},"b1ea2377-9f12-4655-8dca-56413091ade6",[],[3907],{"id":3908,"sortIndex":25,"affiliation":3909,"properties":24},"6585fa1e-be15-4caa-bc6f-6f1772aec561",{"id":3910,"createTime":3911,"updateTime":3911,"relativeEntities":3912,"slug":3913,"properties":3914,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"2004cb3b-4774-419f-849a-da06336147c5","2024-10-11T05:52:15.474+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatrics-Emory-University-School-of-Medicine-Atlanta-Georgia-USA",{"title":3915},{"EN":3916},"Division of Pediatric Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA",{"openalex":3918,"orcid":3920,"title":3922},{"VOID":3919},"A5023838289",{"VOID":3921},"https:\u002F\u002Forcid.org\u002F0000-0003-0416-5171",{"EN":3923},"Preeti Jaggi",{"id":3925,"sortIndex":25,"researcher":24,"roles":3926,"affiliations":3927,"properties":3939},"eea5fdf7-d39e-474f-8f1f-d6dfe850af39",[],[3928],{"id":3929,"sortIndex":25,"affiliation":3930,"properties":24},"e5f68255-de6a-4c74-9006-0fa242a2880e",{"id":3931,"createTime":3932,"updateTime":3933,"relativeEntities":3934,"slug":3935,"properties":3936,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"cd40c7f6-56a7-406d-b296-8c1a6c71eabd","2024-09-28T19:04:49.285+00:00","2024-10-11T05:52:15.356+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatrics-Vanderbilt-University-Medical-Center-Nashville-Tennessee-USA",{"title":3937},{"EN":3938},"Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center , Nashville, Tennessee , USA",{"openalex":3940,"orcid":3941,"title":3942},{"VOID":2952},{"VOID":2954},{"EN":2956},{"id":3944,"sortIndex":376,"researcher":24,"roles":3945,"affiliations":3946,"properties":3957},"bf4d48e7-1f49-4041-9c6a-19fdf1093a01",[],[3947],{"id":3948,"sortIndex":25,"affiliation":3949,"properties":24},"6da71736-d89a-4ed4-a19e-eeb4a701b644",{"id":3950,"createTime":3951,"updateTime":3951,"relativeEntities":3952,"slug":3953,"properties":3954,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"53ac52f1-957a-4d1f-aa9c-a034fffdc277","2024-10-11T05:52:15.426+00:00",[],"Division-of-Infectious-Diseases-and-Immunology-Department-of-Pediatrics-Connecticut-Children-s-Hartford-Connecticut-USA",{"title":3955},{"EN":3956},"Division of Infectious Diseases and Immunology, Department of Pediatrics, Connecticut Children's, Hartford, Connecticut, USA",{"openalex":3958,"title":3960},{"VOID":3959},"A5042098349",{"EN":3961},"Hassan El Chebib",{"id":3963,"sortIndex":62,"researcher":24,"roles":3964,"affiliations":3965,"properties":3976},"f7c84b49-d42d-4bd5-acca-964eb87828b9",[],[3966],{"id":3967,"sortIndex":25,"affiliation":3968,"properties":24},"c1f2e2e6-d6a2-473f-b058-5bd7db3bd8b4",{"id":3969,"createTime":3970,"updateTime":3970,"relativeEntities":3971,"slug":3972,"properties":3973,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"7ad1e453-d02e-4661-baca-2ca597a21f53","2024-10-11T05:52:15.406+00:00",[],"Division-of-Pediatric-Critical-Care-Medicine-Department-of-Pediatrics-University-of-Colorado-School-of-Medicine-Denver-Colorado-USA",{"title":3974},{"EN":3975},"Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado, USA",{"openalex":3977,"orcid":3979,"title":3981},{"VOID":3978},"A5055445432",{"VOID":3980},"https:\u002F\u002Forcid.org\u002F0000-0002-6090-6336",{"EN":3982},"Michele Loi",{"id":3984,"sortIndex":233,"researcher":24,"roles":3985,"affiliations":3986,"properties":3997},"b1c398e1-98d2-44d4-8a19-c0515bac1dcc",[],[3987],{"id":3988,"sortIndex":25,"affiliation":3989,"properties":24},"b3041eb3-1168-412f-bda4-5c55cec6e85f",{"id":3990,"createTime":3991,"updateTime":3991,"relativeEntities":3992,"slug":3993,"properties":3994,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"a134b1fc-2842-45f6-b252-2ea6b36e79fc","2024-10-11T05:52:15.385+00:00",[],"Division-of-Pediatric-Hematology-Oncology-Department-of-Pediatrics-Vanderbilt-University-Medical-Center-Nashville-Tennessee-USA",{"title":3995},{"EN":3996},"Division of Pediatric Hematology Oncology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA",{"openalex":3998,"orcid":4000,"title":4002},{"VOID":3999},"A5053216827",{"VOID":4001},"https:\u002F\u002Forcid.org\u002F0000-0001-7223-375X",{"EN":4003},"James A. Connelly",{"id":4005,"sortIndex":294,"researcher":24,"roles":4006,"affiliations":4007,"properties":4019},"4abcf828-5a99-46ab-b0c4-7d91c028e24f",[],[4008],{"id":4009,"sortIndex":25,"affiliation":4010,"properties":24},"229736b5-657d-421f-828f-8ea3966b4d56",{"id":4011,"createTime":4012,"updateTime":4013,"relativeEntities":4014,"slug":4015,"properties":4016,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"dff07613-48db-4bee-9d47-646e645131f4","2024-01-16T01:28:35.819+00:00","2024-10-11T05:52:15.437+00:00",[],"Division-of-Pediatric-Hematology-Oncology-Department-of-Pediatrics-Emory-University-School-of-Medicine-Atlanta-Georgia-USA",{"title":4017},{"VI":4018},"Division of Pediatric Hematology\u002FOncology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA",{"openalex":4020,"orcid":4022,"title":4024},{"VOID":4021},"A5033127670",{"VOID":4023},"https:\u002F\u002Forcid.org\u002F0000-0001-8007-9932",{"EN":4025},"Shanmuganathan Chandrakasan",{"id":4027,"sortIndex":209,"researcher":24,"roles":4028,"affiliations":4029,"properties":4040},"1fe63945-0d9c-4131-85a9-7e31e96c50eb",[],[4030],{"id":4031,"sortIndex":25,"affiliation":4032,"properties":24},"d5f2d4ba-53aa-4411-a7a9-2b98a793a72c",{"id":4033,"createTime":4034,"updateTime":4034,"relativeEntities":4035,"slug":4036,"properties":4037,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"20d166b8-8d04-4bfd-9758-112ee64c16a4","2024-10-11T05:52:15.346+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatrics-University-of-Michigan-Medical-School-Ann-Arbor-Michigan-USA",{"title":4038},{"EN":4039},"Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA",{"openalex":4041,"orcid":4042,"title":4043},{"VOID":2634},{"VOID":2636},{"EN":2638},{"id":4045,"sortIndex":166,"researcher":24,"roles":4046,"affiliations":4047,"properties":4058},"a60c482f-9dfb-4c08-921e-47d683d4e411",[],[4048],{"id":4049,"sortIndex":25,"affiliation":4050,"properties":24},"ccb81213-d24a-4f92-8f3b-1967fbb9d087",{"id":4051,"createTime":4052,"updateTime":4052,"relativeEntities":4053,"slug":4054,"properties":4055,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"b0951f4f-6f08-4bf8-9d9a-ddef9eb93f02","2024-10-11T05:52:15.376+00:00",[],"Section-of-Rheumatology-Department-of-Pediatrics-University-of-Colorado-School-of-Medicine-Aurora-Colorado-USA",{"title":4056},{"EN":4057},"Section of Rheumatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA",{"openalex":4059,"orcid":4061,"title":4063},{"VOID":4060},"A5073464643",{"VOID":4062},"https:\u002F\u002Forcid.org\u002F0000-0002-0911-9310",{"EN":4064},"Robert C. Fuhlbrigge",{"id":4066,"sortIndex":150,"researcher":24,"roles":4067,"affiliations":4068,"properties":4080},"73f5e9d0-96b3-4857-a77b-717c073e0848",[],[4069],{"id":4070,"sortIndex":25,"affiliation":4071,"properties":24},"d9617d64-cec8-456c-816a-a7e3d59457a6",{"id":4072,"createTime":4073,"updateTime":4074,"relativeEntities":4075,"slug":4076,"properties":4077,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"058402cd-dc7b-4912-8d12-172d0200b596","2024-10-11T05:52:15.454+00:00","2025-06-11T18:41:10.720+00:00",[],"Division-of-Oncology-Department-of-Pediatrics-Children-s-Hospital-of-Philadelphia-University-of-Pennsylvania-Perelman-School-of-Medicine-Philadelphia-Pennsylvania-USA",{"title":4078},{"EN":4079},"Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA",{"openalex":4081,"orcid":4082,"title":4083},{"VOID":1515},{"VOID":1517},{"EN":1519},{"id":4085,"sortIndex":706,"researcher":24,"roles":4086,"affiliations":4087,"properties":4105},"1106f926-f7f4-4099-b92b-c9b7cfe8f2fc",[],[4088,4099],{"id":4089,"sortIndex":166,"affiliation":4090,"properties":24},"3b9a368f-917e-4a0d-8604-e808e012837d",{"id":4091,"createTime":4092,"updateTime":4093,"relativeEntities":4094,"slug":4095,"properties":4096,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"80cbe78a-c833-4596-8879-48cd6050c4a2","2023-12-08T07:52:33.277+00:00","2024-10-11T05:52:15.515+00:00",[],"University-of-Connecticut-School-of-Pharmacy-Storrs-Connecticut-USA",{"title":4097},{"VI":4098},"University of Connecticut School of Pharmacy, Storrs, Connecticut, USA",{"id":4100,"sortIndex":25,"affiliation":4101,"properties":24},"5ebf0ab9-c7c8-4a9e-abae-64f0e0fd5bc5",{"id":3950,"createTime":3951,"updateTime":3951,"relativeEntities":4102,"slug":3953,"properties":4103,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":4104},{"EN":3956},{"openalex":4106,"orcid":4108,"title":4110},{"VOID":4107},"A5006518206",{"VOID":4109},"https:\u002F\u002Forcid.org\u002F0000-0002-7905-6810",{"EN":4111},"Jennifer E Girotto",{"id":4113,"sortIndex":272,"researcher":24,"roles":4114,"affiliations":4115,"properties":4127},"fdb530de-8778-400d-8d4d-c0ab9f4ee8b6",[],[4116],{"id":4117,"sortIndex":25,"affiliation":4118,"properties":24},"1cfa69a5-5ee6-4852-aa05-6055c5b4a36a",{"id":4119,"createTime":4120,"updateTime":4121,"relativeEntities":4122,"slug":4123,"properties":4124,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"dd3b52b5-21b0-4e40-9677-129415ea64be","2023-12-01T07:35:55.591+00:00","2024-10-11T05:52:15.416+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Children-s-Hospital-of-Philadelphia-University-of-Pennsylvania-Perelman-School-of-Medicine-Philadelphia-Pennsylvania-USA",{"title":4125},{"VI":4126},"Division of Infectious Diseases, Department of Pediatrics, Children’s Hospital of Philadelphia, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, USA",{"openalex":4128,"orcid":4130,"title":4132},{"VOID":4129},"A5045563269",{"VOID":4131},"https:\u002F\u002Forcid.org\u002F0000-0001-7959-1445",{"EN":4133},"W Otto",{"id":4135,"sortIndex":2870,"researcher":24,"roles":4136,"affiliations":4137,"properties":4144},"9b69b4cc-b086-464e-b9f1-cfda9b138be2",[],[4138],{"id":4139,"sortIndex":25,"affiliation":4140,"properties":24},"5c2dec32-e096-4390-8966-98e0dac91329",{"id":4119,"createTime":4120,"updateTime":4121,"relativeEntities":4141,"slug":4123,"properties":4142,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":4143},{"VI":4126},{"openalex":4145,"orcid":4146,"title":4147},{"VOID":1555},{"VOID":1557},{"EN":1559},{"id":4149,"sortIndex":185,"researcher":24,"roles":4150,"affiliations":4151,"properties":4162},"7ff8e245-70c2-45a3-973d-b1c082d34adb",[],[4152],{"id":4153,"sortIndex":25,"affiliation":4154,"properties":24},"41671053-0795-4970-9538-64f2be887eaf",{"id":4155,"createTime":4156,"updateTime":4156,"relativeEntities":4157,"slug":4158,"properties":4159,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"950b4c4b-0ba4-407e-8e7b-135c0bb9f28d","2024-10-11T05:52:15.464+00:00",[],"Division-of-Critical-Care-Medicine-Department-of-Pediatrics-Children-s-Hospital-of-Philadelphia-University-of-Pennsylvania-Perelman-School-of-Medicine-Philadelphia-Pennsylvania-USA",{"title":4160},{"EN":4161},"Division of Critical Care Medicine, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA",{"openalex":4163,"orcid":4165,"title":4167},{"VOID":4164},"A5026320384",{"VOID":4166},"https:\u002F\u002Forcid.org\u002F0000-0002-7054-8798",{"EN":4168},"Garrett Keim",{"id":4170,"sortIndex":354,"researcher":24,"roles":4171,"affiliations":4172,"properties":4183},"29a5df0f-a5c8-4e15-9e13-8089637652f9",[],[4173],{"id":4174,"sortIndex":25,"affiliation":4175,"properties":24},"64a3e880-f5f5-4598-9af5-af32a161d8e4",{"id":4176,"createTime":4177,"updateTime":4177,"relativeEntities":4178,"slug":4179,"properties":4180,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"f490c922-2bb5-40b5-9378-c48e6176f57b","2024-10-11T05:52:15.494+00:00",[],"Division-of-Pediatric-Hematology-Oncology-Department-of-Pediatrics-University-of-Michigan-Medical-School-Ann-Arbor-Michigan-USA",{"title":4181},{"EN":4182},"Division of Pediatric Hematology Oncology, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA",{"openalex":4184,"title":4186},{"VOID":4185},"A5046074908",{"EN":4187},"Kelly Walkovich",{"url":24,"publisher":4189,"properties":4214},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":4190,"slug":10,"properties":4191,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":4197,"manageAffiliations":4198,"indexDatabases":4199,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":4192,"issn":4193,"introduce":4194,"eissn":4195,"title":4196},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[4200,4207],{"id":76,"indexDatabase":4201,"url":91,"indexYears":24,"academicFieldIds":4206,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":4202,"label":4203,"description":4204,"key":87,"publicationTags":4205,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":4208,"url":109,"indexYears":110,"academicFieldIds":4213,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":4209,"label":4210,"description":4211,"key":106,"publicationTags":4212,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":4215,"pages":4216,"issue":4218},{"VOID":427},{"VOID":4217},"716-737",{"VOID":4219},"6",52,{"total":4220,"publishYear":24,"statisticByYear":4222},{"2020":62,"2021":3112,"2022":2870,"2023":185,"2024":166},"2020-12-31",[4225,4229,4233,4236,4240,4243,4246,4250,4254,4258,4262,4266,4270,4273,4277,4281,4285,4289,4293,4297,4301,4305,4309,4313,4317,4321,4325,4329,4333,4337,4341,4345,4349,4353,4355,4359,4361,4364,4367,4369,4373,4377,4381,4385,4389,4392,4395,4399,4403,4406,4410,4414,4418,4422,4426,4430,4434,4438,4442,4446,4450,4454,4458,4462,4466,4470,4474,4477,4481,4485,4489,4493,4497,4501,4505,4507,4511,4515,4518,4521,4525,4529,4533,4537,4541,4545,4549,4553,4557,4561,4565,4569,4573,4577,4581,4585,4589,4593,4597,4601,4605,4609,4613,4617,4621,4625,4629,4633,4636,4640,4644,4648,4652,4656,4660,4664,4668,4672,4675,4679,4683,4687,4691,4695,4699,4703,4707,4711,4715,4719,4723,4727,4731,4735,4739,4743,4747,4751,4755,4758,4762,4765,4769,4773,4777,4781,4784,4787,4791,4795,4799,4803,4806,4810,4814,4818,4820,4824,4828,4832,4836,4840,4844,4848,4852,4856,4860,4864,4867,4871,4875,4879,4883,4887,4891,4895,4899,4903,4907,4911,4915,4918,4922,4926,4930,4934,4938,4942,4944,4948,4952,4956,4960,4964,4968,4972,4976,4980,4984,4988,4992,4996,5000,5004,5008,5010,5014,5017,5020,5024,5028,5032,5036,5040,5044,5048,5052,5056,5060,5064,5068,5072,5076,5080,5084,5088,5092,5096,5100,5104,5108,5112,5116,5120,5124,5128,5132],{"id":24,"text":4226,"url":24,"identifiers":4227},"Li, 2020, Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia, N Engl J Med, 382, 1199, 10.1056\u002FNEJMoa2001316",{"doi":4228},"10.1056\u002FNEJMoa2001316",{"id":24,"text":4230,"url":24,"identifiers":4231},"Liu, 2020, Detection of Covid-19 in children in early January 2020 in Wuhan, China, N Engl J Med, 382, 1370, 10.1056\u002FNEJMc2003717",{"doi":4232},"10.1056\u002FNEJMc2003717",{"id":24,"text":4234,"url":24,"identifiers":4235},"CDC COVID-19 Response Team, 2020, Coronavirus disease 2019 in children—United States, February 12–April 2, 2020, MMWR Morb Mortal Wkly Rep, 69, 422, 10.15585\u002Fmmwr.mm6914e4",{"doi":3377},{"id":24,"text":4237,"url":24,"identifiers":4238},"Wu, 2020;, Co-infection and other clinical characteristics of COVID-19 in children, Pediatrics, 146, e20200961, 10.1542\u002Fpeds.2020-0961",{"doi":4239},"10.1542\u002Fpeds.2020-0961",{"id":24,"text":4241,"url":24,"identifiers":4242},"Shekerdemian, 2020, Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units [manuscript published online ahead of print May 11, 2020], JAMA Pediatr, 10.1001\u002Fjamapediatrics.2020.1948",{"doi":828},{"id":24,"text":4244,"url":24,"identifiers":4245},"CDC COVID-19 Response Team, 2020, Severe outcomes among patients with coronavirus disease 2019 (COVID-19)—United States, February 12–March 16, 2020, MMWR Morb Mortal Wkly Rep, 69, 343, 10.15585\u002Fmmwr.mm6912e2",{"doi":3416},{"id":24,"text":4247,"url":24,"identifiers":4248},"Guan, 2020;, Comorbidity and its impact on 1590 patients with Covid-19 in China: a nationwide analysis, Eur Respir J, 55, 2000547, 10.1183\u002F13993003.00547-2020",{"doi":4249},"10.1183\u002F13993003.00547-2020",{"id":24,"text":4251,"url":24,"identifiers":4252},"Castagnoli, 2020, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review [manuscript published online ahead of print April 22, 2020], JAMA Pediatr, 10.1001\u002Fjamapediatrics.2020.1467",{"doi":4253},"10.1001\u002Fjamapediatrics.2020.1467",{"id":24,"text":4255,"url":24,"identifiers":4256},"Zhu, 2020, A novel coronavirus from patients with pneumonia in China, 2019, N Engl J Med, 382, 727, 10.1056\u002FNEJMoa2001017",{"doi":4257},"10.1056\u002FNEJMoa2001017",{"id":24,"text":4259,"url":24,"identifiers":4260},"Huang, 2020, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet, 395, 497, 10.1016\u002FS0140-6736(20)30183-5",{"doi":4261},"10.1016\u002FS0140-6736(20)30183-5",{"id":24,"text":4263,"url":24,"identifiers":4264},"Chen, 2020, Clinical and immunological features of severe and moderate coronavirus disease 2019, J Clin Invest, 130, 2620, 10.1172\u002FJCI137244",{"doi":4265},"10.1172\u002FJCI137244",{"id":24,"text":4267,"url":24,"identifiers":4268},"Mo, 2020, Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China [manuscript published online ahead of print March 16, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa270",{"doi":4269},"10.1093\u002Fcid\u002Fciaa270",{"id":24,"text":4271,"url":24,"identifiers":4272},"Wang, 2020, Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China, JAMA, 323, 1061, 10.1001\u002Fjama.2020.1585",{"doi":3629},{"id":24,"text":4274,"url":24,"identifiers":4275},"Shi, 2020, Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China, JAMA Cardiol, 5, 802, 10.1001\u002Fjamacardio.2020.0950",{"doi":4276},"10.1001\u002Fjamacardio.2020.0950",{"id":24,"text":4278,"url":24,"identifiers":4279},"Inciardi, 2020, Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19), JAMA Cardiol, 5, 1, 10.1001\u002Fjamacardio.2020.1096",{"doi":4280},"10.1001\u002Fjamacardio.2020.1096",{"id":24,"text":4282,"url":24,"identifiers":4283},"Tisoncik, 2012, Into the eye of the cytokine storm, Microbiol Mol Biol Rev, 76, 16, 10.1128\u002FMMBR.05015-11",{"doi":4284},"10.1128\u002FMMBR.05015-11",{"id":24,"text":4286,"url":24,"identifiers":4287},"Channappanavar, 2017, Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology, Semin Immunopathol, 39, 529, 10.1007\u002Fs00281-017-0629-x",{"doi":4288},"10.1007\u002Fs00281-017-0629-x",{"id":24,"text":4290,"url":24,"identifiers":4291},"Huang, 2005, An interferon-gamma-related cytokine storm in SARS patients, J Med Virol, 75, 185, 10.1002\u002Fjmv.20255",{"doi":4292},"10.1002\u002Fjmv.20255",{"id":24,"text":4294,"url":24,"identifiers":4295},"Zhang, 2004, Analysis of serum cytokines in patients with severe acute respiratory syndrome, Infect Immun, 72, 4410, 10.1128\u002FIAI.72.8.4410-4415.2004",{"doi":4296},"10.1128\u002FIAI.72.8.4410-4415.2004",{"id":24,"text":4298,"url":24,"identifiers":4299},"Nicholls, 2003, Lung pathology of fatal severe acute respiratory syndrome, Lancet, 361, 1773, 10.1016\u002FS0140-6736(03)13413-7",{"doi":4300},"10.1016\u002FS0140-6736(03)13413-7",{"id":24,"text":4302,"url":24,"identifiers":4303},"Gu, 2005, Multiple organ infection and the pathogenesis of SARS, J Exp Med, 202, 415, 10.1084\u002Fjem.20050828",{"doi":4304},"10.1084\u002Fjem.20050828",{"id":24,"text":4306,"url":24,"identifiers":4307},"de Jong, 2006, Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia, Nat Med, 12, 1203, 10.1038\u002Fnm1477",{"doi":4308},"10.1038\u002Fnm1477",{"id":24,"text":4310,"url":24,"identifiers":4311},"Huang, 2014, Profiles of acute cytokine and antibody responses in patients infected with avian influenza A H7N9, PLoS One, 9, e101788, 10.1371\u002Fjournal.pone.0101788",{"doi":4312},"10.1371\u002Fjournal.pone.0101788",{"id":24,"text":4314,"url":24,"identifiers":4315},"Arankalle, 2010, Role of host immune response and viral load in the differential outcome of pandemic H1N1 (2009) influenza virus infection in Indian patients, PLoS One, 5, e13099, 10.1371\u002Fjournal.pone.0013099",{"doi":4316},"10.1371\u002Fjournal.pone.0013099",{"id":24,"text":4318,"url":24,"identifiers":4319},"Lee, 2011, Cytokine response patterns in severe pandemic 2009 H1N1 and seasonal influenza among hospitalized adults, PLoS One, 6, e26050, 10.1371\u002Fjournal.pone.0026050",{"doi":4320},"10.1371\u002Fjournal.pone.0026050",{"id":24,"text":4322,"url":24,"identifiers":4323},"Schulert, 2016, Whole-exome sequencing reveals mutations in genes linked to hemophagocytic lymphohistiocytosis and macrophage activation syndrome in fatal cases of H1N1 influenza, J Infect Dis, 213, 1180, 10.1093\u002Finfdis\u002Fjiv550",{"doi":4324},"10.1093\u002Finfdis\u002Fjiv550",{"id":24,"text":4326,"url":24,"identifiers":4327},"Baseler, 2016, An acute immune response to Middle East respiratory syndrome coronavirus replication contributes to viral pathogenicity, Am J Pathol, 186, 630, 10.1016\u002Fj.ajpath.2015.10.025",{"doi":4328},"10.1016\u002Fj.ajpath.2015.10.025",{"id":24,"text":4330,"url":24,"identifiers":4331},"Arabi, 2014, Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection, Ann Intern Med, 160, 389, 10.7326\u002FM13-2486",{"doi":4332},"10.7326\u002FM13-2486",{"id":24,"text":4334,"url":24,"identifiers":4335},"Ng, 2016, Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of Middle East respiratory syndrome coronavirus infection in the United Arab Emirates, April 2014, Am J Pathol, 186, 652, 10.1016\u002Fj.ajpath.2015.10.024",{"doi":4336},"10.1016\u002Fj.ajpath.2015.10.024",{"id":24,"text":4338,"url":24,"identifiers":4339},"Grom, 2016, Macrophage activation syndrome in the era of biologic therapy, Nat Rev Rheumatol, 12, 259, 10.1038\u002Fnrrheum.2015.179",{"doi":4340},"10.1038\u002Fnrrheum.2015.179",{"id":24,"text":4342,"url":24,"identifiers":4343},"Carlisle, 2019, A banner year for immunotherapy and targeted therapy, Nat Rev Clin Oncol, 16, 79, 10.1038\u002Fs41571-018-0138-4",{"doi":4344},"10.1038\u002Fs41571-018-0138-4",{"id":24,"text":4346,"url":24,"identifiers":4347},"Kumar, 2017, Future prospects of biologic therapies for immunologic diseases, Immunol Allergy Clin North Am, 37, 431, 10.1016\u002Fj.iac.2017.01.013",{"doi":4348},"10.1016\u002Fj.iac.2017.01.013",{"id":24,"text":4350,"url":24,"identifiers":4351},"Frey, 2019, Cytokine release syndrome with chimeric antigen receptor T cell therapy, Biol Blood Marrow Transplant, 25, e123, 10.1016\u002Fj.bbmt.2018.12.756",{"doi":4352},"10.1016\u002Fj.bbmt.2018.12.756",{"id":24,"text":3434,"url":24,"identifiers":4354},{"doi":3436},{"id":24,"text":4356,"url":24,"identifiers":4357},"Jones, 2020, COVID-19 and Kawasaki disease: novel virus and novel case, Hosp Pediatr, 10, 537, 10.1542\u002Fhpeds.2020-0123",{"doi":4358},"10.1542\u002Fhpeds.2020-0123",{"id":24,"text":810,"url":24,"identifiers":4360},{"doi":812},{"id":24,"text":4362,"url":24,"identifiers":4363},"European Centre for Disease Prevention and Control",{},{"id":24,"text":4365,"url":24,"identifiers":4366},"Deza Leon, 2020, COVID-19-associated pediatric multisystem inflammatory syndrome, J Pediatric Infect Dis Soc, 9, 407, 10.1093\u002Fjpids\u002Fpiaa061",{"doi":140},{"id":24,"text":1672,"url":24,"identifiers":4368},{},{"id":24,"text":4370,"url":24,"identifiers":4371},"Zhang, 2020, First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab, Blood Adv, 4, 1307, 10.1182\u002Fbloodadvances.2020001907",{"doi":4372},"10.1182\u002Fbloodadvances.2020001907",{"id":24,"text":4374,"url":24,"identifiers":4375},"Michot, 2020, Tocilizumab, an anti-IL-6 receptor antibody, to treat COVID-19-related respiratory failure: a case report, Ann Oncol, 31, 961, 10.1016\u002Fj.annonc.2020.03.300",{"doi":4376},"10.1016\u002Fj.annonc.2020.03.300",{"id":24,"text":4378,"url":24,"identifiers":4379},"Luo, 2020, Tocilizumab treatment in COVID-19: a single center experience, J Med Virol, 92, 814, 10.1002\u002Fjmv.25801",{"doi":4380},"10.1002\u002Fjmv.25801",{"id":24,"text":4382,"url":24,"identifiers":4383},"De Luna, 2020, Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab, Am J Hematol, 95, 876, 10.1002\u002Fajh.25833",{"doi":4384},"10.1002\u002Fajh.25833",{"id":24,"text":4386,"url":24,"identifiers":4387},"Di Giambenedetto, 2020, Off-label use of tocilizumab in patients with SARS-CoV-2 infection [manuscript published online ahead of print April 16, 2020], J Med Virol, 10.1002\u002Fjmv.25897",{"doi":4388},"10.1002\u002Fjmv.25897",{"id":24,"text":4390,"url":24,"identifiers":4391},"Chiotos, 2020, Multisystem inflammatory syndrome in children during the coronavirus 2019 pandemic: a case series, J Pediatric Infect Dis Soc, 9, 393, 10.1093\u002Fjpids\u002Fpiaa069",{"doi":1407},{"id":24,"text":4393,"url":24,"identifiers":4394},"Gotzinger, 2020, COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study [manuscript published online ahead of print June 25, 2020], Lancet Child Adolesc Health, 10.1016\u002FS2352-4642(20)30177-2",{"doi":3388},{"id":24,"text":4396,"url":24,"identifiers":4397},"Derespina, 2020, Clinical manifestations and outcomes of critically ill children and adolescents with COVID-19 in New York City [manuscript published online ahead of print July 15, 2020], J Pediatr, 10.1016\u002Fj.jpeds.2020.07.039",{"doi":4398},"10.1016\u002Fj.jpeds.2020.07.039",{"id":24,"text":4400,"url":24,"identifiers":4401},"Menter, 2020, Post-mortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction [manuscript published online ahead of print May 4, 2020], Histopathology, 10.1111\u002Fhis.14134",{"doi":4402},"10.1111\u002Fhis.14134",{"id":24,"text":4404,"url":24,"identifiers":4405},"Wichmann, 2020, Autopsy findings and venous thromboembolism in patients with COVID-19 [manuscript published online ahead of print May 6, 2020], Ann Intern Med",{},{"id":24,"text":4407,"url":24,"identifiers":4408},"Henry, 2020, Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis, Clin Chem Lab Med, 58, 1021, 10.1515\u002Fcclm-2020-0369",{"doi":4409},"10.1515\u002Fcclm-2020-0369",{"id":24,"text":4411,"url":24,"identifiers":4412},"Connors, 2020, COVID-19 and its implications for thrombosis and anticoagulation, Blood, 135, 2033, 10.1182\u002Fblood.2020006000",{"doi":4413},"10.1182\u002Fblood.2020006000",{"id":24,"text":4415,"url":24,"identifiers":4416},"Yang, 2020, Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19, J Allergy Clin Immunol, 146, 119, 10.1016\u002Fj.jaci.2020.04.027",{"doi":4417},"10.1016\u002Fj.jaci.2020.04.027",{"id":24,"text":4419,"url":24,"identifiers":4420},"Wen, 2020, Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing, Cell Discov, 6, 31, 10.1038\u002Fs41421-020-0168-9",{"doi":4421},"10.1038\u002Fs41421-020-0168-9",{"id":24,"text":4423,"url":24,"identifiers":4424},"Hadjadj, 2020, Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients, Science, 369, 718, 10.1126\u002Fscience.abc6027",{"doi":4425},"10.1126\u002Fscience.abc6027",{"id":24,"text":4427,"url":24,"identifiers":4428},"Trouillet-Assant, 2020, Type I IFN immunoprofiling in COVID-19 patients, J Allergy Clin Immunol, 146, 206, 10.1016\u002Fj.jaci.2020.04.029",{"doi":4429},"10.1016\u002Fj.jaci.2020.04.029",{"id":24,"text":4431,"url":24,"identifiers":4432},"Blanco-Melo, 2020, Imbalanced host response to SARS-CoV-2 drives development of COVID-19, Cell, 181, 1036, 10.1016\u002Fj.cell.2020.04.026",{"doi":4433},"10.1016\u002Fj.cell.2020.04.026",{"id":24,"text":4435,"url":24,"identifiers":4436},"Channappanavar, 2016, Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice, Cell Host Microbe, 19, 181, 10.1016\u002Fj.chom.2016.01.007",{"doi":4437},"10.1016\u002Fj.chom.2016.01.007",{"id":24,"text":4439,"url":24,"identifiers":4440},"Aouba, 2020, Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series [manuscript published online ahead of print May 6, 2020], Ann Rheum Dis, 10.1136\u002Fannrheumdis-2020-217706",{"doi":4441},"10.1136\u002Fannrheumdis-2020-217706",{"id":24,"text":4443,"url":24,"identifiers":4444},"Cavalli, 2020, Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study, Lancet Rheumatol, 2, e325, 10.1016\u002FS2665-9913(20)30127-2",{"doi":4445},"10.1016\u002FS2665-9913(20)30127-2",{"id":24,"text":4447,"url":24,"identifiers":4448},"Dimopoulos, 2020, Favorable anakinra responses in severe Covid-19 patients with secondary hemophagocytic lymphohistiocytosis, Cell Host Microbe, 28, 117, 10.1016\u002Fj.chom.2020.05.007",{"doi":4449},"10.1016\u002Fj.chom.2020.05.007",{"id":24,"text":4451,"url":24,"identifiers":4452},"Alattar, 2020, Tocilizumab for the treatment of severe coronavirus disease 2019 [manuscript published online ahead of print May 5, 2020], J Med Virol, 10.1002\u002Fjmv.25964",{"doi":4453},"10.1002\u002Fjmv.25964",{"id":24,"text":4455,"url":24,"identifiers":4456},"Uciechowski, 2020, Interleukin-6: a masterplayer in the cytokine network, Oncology, 98, 131, 10.1159\u002F000505099",{"doi":4457},"10.1159\u002F000505099",{"id":24,"text":4459,"url":24,"identifiers":4460},"Kopf, 1994, Impaired immune and acute-phase responses in interleukin-6-deficient mice, Nature, 368, 339, 10.1038\u002F368339a0",{"doi":4461},"10.1038\u002F368339a0",{"id":24,"text":4463,"url":24,"identifiers":4464},"Harker, 2011, Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection, Science, 334, 825, 10.1126\u002Fscience.1208421",{"doi":4465},"10.1126\u002Fscience.1208421",{"id":24,"text":4467,"url":24,"identifiers":4468},"Kuo, 2009, HBV replication is significantly reduced by IL-6, J Biomed Sci, 16, 41, 10.1186\u002F1423-0127-16-41",{"doi":4469},"10.1186\u002F1423-0127-16-41",{"id":24,"text":4471,"url":24,"identifiers":4472},"Lauder, 2013, Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology, Eur J Immunol, 43, 2613, 10.1002\u002Feji.201243018",{"doi":4473},"10.1002\u002Feji.201243018",{"id":24,"text":4475,"url":24,"identifiers":4476},"US Food and Drug Administration",{},{"id":24,"text":4478,"url":24,"identifiers":4479},"Lau, 2013, Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment, J Gen Virol, 94, 2679, 10.1099\u002Fvir.0.055533-0",{"doi":4480},"10.1099\u002Fvir.0.055533-0",{"id":24,"text":4482,"url":24,"identifiers":4483},"Zhou, 2014, Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis, J Infect Dis, 209, 1331, 10.1093\u002Finfdis\u002Fjit504",{"doi":4484},"10.1093\u002Finfdis\u002Fjit504",{"id":24,"text":4486,"url":24,"identifiers":4487},"Wang, 2007, Up-regulation of IL-6 and TNF-alpha induced by SARS-coronavirus spike protein in murine macrophages via NF-kappaB pathway, Virus Res, 128, 1, 10.1016\u002Fj.virusres.2007.02.007",{"doi":4488},"10.1016\u002Fj.virusres.2007.02.007",{"id":24,"text":4490,"url":24,"identifiers":4491},"Zhang, 2007, Nucleocapsid protein of SARS-CoV activates interleukin-6 expression through cellular transcription factor NF-kappaB, Virology, 365, 324, 10.1016\u002Fj.virol.2007.04.009",{"doi":4492},"10.1016\u002Fj.virol.2007.04.009",{"id":24,"text":4494,"url":24,"identifiers":4495},"Cameron, 2012, Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model, PLoS One, 7, e45842, 10.1371\u002Fjournal.pone.0045842",{"doi":4496},"10.1371\u002Fjournal.pone.0045842",{"id":24,"text":4498,"url":24,"identifiers":4499},"Chen, 2020, Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients [manuscript published online ahead of print April 17, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa449",{"doi":4500},"10.1093\u002Fcid\u002Fciaa449",{"id":24,"text":4502,"url":24,"identifiers":4503},"Ruan, 2020, Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China, Intensive Care Med, 46, 846, 10.1007\u002Fs00134-020-05991-x",{"doi":4504},"10.1007\u002Fs00134-020-05991-x",{"id":24,"text":3539,"url":24,"identifiers":4506},{"doi":3541},{"id":24,"text":4508,"url":24,"identifiers":4509},"Somers, 2020, Tocilizumab for treatment of mechanically ventilated patients with COVID-19 [manuscript published online ahead of print July 11, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa954",{"doi":4510},"10.1093\u002Fcid\u002Fciaa954",{"id":24,"text":4512,"url":24,"identifiers":4513},"Guaraldi, 2020, Tocilizumab in patients with severe COVID-19: a retrospective cohort study, Lancet Rheumatol, 10.1016\u002FS2665-9913(20)30173-9",{"doi":4514},"10.1016\u002FS2665-9913(20)30173-9",{"id":24,"text":4516,"url":24,"identifiers":4517},"Price, 2020, Tocilizumab treatment for cytokine release syndrome in hospitalized COVID-19 patients: survival and clinical outcomes [manuscript published online ahead of print June 15, 2020], Chest",{},{"id":24,"text":4519,"url":24,"identifiers":4520},"Sciascia, 2020, Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19, Clin Exp Rheumatol, 38, 529",{},{"id":24,"text":4522,"url":24,"identifiers":4523},"Campochiaro, 2020, Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study, Eur J Intern Med, 76, 43, 10.1016\u002Fj.ejim.2020.05.021",{"doi":4524},"10.1016\u002Fj.ejim.2020.05.021",{"id":24,"text":4526,"url":24,"identifiers":4527},"Xu, 2020, Effective treatment of severe COVID-19 patients with tocilizumab, Proc Natl Acad Sci U S A, 117, 10970, 10.1073\u002Fpnas.2005615117",{"doi":4528},"10.1073\u002Fpnas.2005615117",{"id":24,"text":4530,"url":24,"identifiers":4531},"Toniati, 2020, Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: a single center study of 100 patients in Brescia, Italy, Autoimmun Rev, 19, 102568, 10.1016\u002Fj.autrev.2020.102568",{"doi":4532},"10.1016\u002Fj.autrev.2020.102568",{"id":24,"text":4534,"url":24,"identifiers":4535},"Jacobs, 2018, Pneumatosis intestinalis and intestinal perforation in a patient receiving tocilizumab, Arch Rheumatol, 33, 372, 10.5606\u002FArchRheumatol.2018.6668",{"doi":4536},"10.5606\u002FArchRheumatol.2018.6668",{"id":24,"text":4538,"url":24,"identifiers":4539},"Genovese, 2017, Transaminase levels and hepatic events during tocilizumab treatment: pooled analysis of long-term clinical trial safety data in rheumatoid arthritis, Arthritis Rheumatol, 69, 1751, 10.1002\u002Fart.40176",{"doi":4540},"10.1002\u002Fart.40176",{"id":24,"text":4542,"url":24,"identifiers":4543},"Morrison, 2020, Letter to the Editor: acute hypertriglyceridemia in patients with COVID-19 receiving tocilizumab [manuscript published online ahead of print April 21, 2020], J Med Virol, 10.1002\u002Fjmv.25907",{"doi":4544},"10.1002\u002Fjmv.25907",{"id":24,"text":4546,"url":24,"identifiers":4547},"Huet, 2020, Anakinra for severe forms of COVID-19: a cohort study, Lancet Rheumatol, 2, e393, 10.1016\u002FS2665-9913(20)30164-8",{"doi":4548},"10.1016\u002FS2665-9913(20)30164-8",{"id":24,"text":4550,"url":24,"identifiers":4551},"Ucciferri, 2020, Canakinumab in a subgroup of patients with COVID-19, Lancet Rheumatol, 10.1016\u002FS2665-9913(20)30167-3",{"doi":4552},"10.1016\u002FS2665-9913(20)30167-3",{"id":24,"text":4554,"url":24,"identifiers":4555},"Chung, 2009, Critical regulation of early Th17 cell differentiation by interleukin-1 signaling, Immunity, 30, 576, 10.1016\u002Fj.immuni.2009.02.007",{"doi":4556},"10.1016\u002Fj.immuni.2009.02.007",{"id":24,"text":4558,"url":24,"identifiers":4559},"Cahill, 2008, Interleukin (IL) 1beta induction of IL-6 is mediated by a novel phosphatidylinositol 3-kinase-dependent AKT\u002FIkappaB kinase alpha pathway targeting activator protein-1, J Biol Chem, 283, 25900, 10.1074\u002Fjbc.M707692200",{"doi":4560},"10.1074\u002Fjbc.M707692200",{"id":24,"text":4562,"url":24,"identifiers":4563},"Cavalli, 2018, Anakinra therapy for non-cancer inflammatory diseases, Front Pharmacol, 9, 1157, 10.3389\u002Ffphar.2018.01157",{"doi":4564},"10.3389\u002Ffphar.2018.01157",{"id":24,"text":4566,"url":24,"identifiers":4567},"Dubois, 2011, Rilonacept and canakinumab, Br J Clin Pharmacol, 71, 639, 10.1111\u002Fj.1365-2125.2011.03958.x",{"doi":4568},"10.1111\u002Fj.1365-2125.2011.03958.x",{"id":24,"text":4570,"url":24,"identifiers":4571},"Nuki, 2002, Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: extension phase of a randomized, double-blind, placebo-controlled trial, Arthritis Rheum, 46, 2838, 10.1002\u002Fart.10578",{"doi":4572},"10.1002\u002Fart.10578",{"id":24,"text":4574,"url":24,"identifiers":4575},"Cohen, 2004, A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate, Ann Rheum Dis, 63, 1062, 10.1136\u002Fard.2003.016014",{"doi":4576},"10.1136\u002Fard.2003.016014",{"id":24,"text":4578,"url":24,"identifiers":4579},"Ilowite, 2014, Randomized, double-blind, placebo-controlled trial of the efficacy and safety of rilonacept in the treatment of systemic juvenile idiopathic arthritis, Arthritis Rheumatol, 66, 2570, 10.1002\u002Fart.38699",{"doi":4580},"10.1002\u002Fart.38699",{"id":24,"text":4582,"url":24,"identifiers":4583},"Hoffman, 2008, Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies, Arthritis Rheum, 58, 2443, 10.1002\u002Fart.23687",{"doi":4584},"10.1002\u002Fart.23687",{"id":24,"text":4586,"url":24,"identifiers":4587},"Koné-Paut, 2011, Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study, Arthritis Res Ther, 13, R202, 10.1186\u002Far3535",{"doi":4588},"10.1186\u002Far3535",{"id":24,"text":4590,"url":24,"identifiers":4591},"De Benedetti, 2018, Canakinumab for the treatment of autoinflammatory recurrent fever syndromes, N Engl J Med, 378, 1908, 10.1056\u002FNEJMoa1706314",{"doi":4592},"10.1056\u002FNEJMoa1706314",{"id":24,"text":4594,"url":24,"identifiers":4595},"Ruperto, 2012, Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis, N Engl J Med, 367, 2396, 10.1056\u002FNEJMoa1205099",{"doi":4596},"10.1056\u002FNEJMoa1205099",{"id":24,"text":4598,"url":24,"identifiers":4599},"Shakoory, 2016, Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial, Crit Care Med, 44, 275, 10.1097\u002FCCM.0000000000001402",{"doi":4600},"10.1097\u002FCCM.0000000000001402",{"id":24,"text":4602,"url":24,"identifiers":4603},"Miettunen, 2011, Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients, Rheumatology (Oxford), 50, 417, 10.1093\u002Frheumatology\u002Fkeq218",{"doi":4604},"10.1093\u002Frheumatology\u002Fkeq218",{"id":24,"text":4606,"url":24,"identifiers":4607},"Eloseily, 2020, Benefit of anakinra in treating pediatric secondary hemophagocytic lymphohistiocytosis, Arthritis Rheumatol, 72, 326, 10.1002\u002Fart.41103",{"doi":4608},"10.1002\u002Fart.41103",{"id":24,"text":4610,"url":24,"identifiers":4611},"Rajasekaran, 2014, Therapeutic role of anakinra, an interleukin-1 receptor antagonist, in the management of secondary hemophagocytic lymphohistiocytosis\u002Fsepsis\u002Fmultiple organ dysfunction\u002Fmacrophage activating syndrome in critically ill children, Pediatr Crit Care Med, 15, 401, 10.1097\u002FPCC.0000000000000078",{"doi":4612},"10.1097\u002FPCC.0000000000000078",{"id":24,"text":4614,"url":24,"identifiers":4615},"Heney, 1995, Factors affecting the measurement of cytokines in biological fluids: implications for their clinical measurement, Ann Clin Biochem, 32(Pt 4), 358, 10.1177\u002F000456329503200402",{"doi":4616},"10.1177\u002F000456329503200402",{"id":24,"text":4618,"url":24,"identifiers":4619},"Chen, 2019, Severe acute respiratory syndrome coronavirus viroporin 3a activates the NLRP3 inflammasome, Front Microbiol, 10, 50, 10.3389\u002Ffmicb.2019.00050",{"doi":4620},"10.3389\u002Ffmicb.2019.00050",{"id":24,"text":4622,"url":24,"identifiers":4623},"Nieto-Torres, 2015, Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome, Virology, 485, 330, 10.1016\u002Fj.virol.2015.08.010",{"doi":4624},"10.1016\u002Fj.virol.2015.08.010",{"id":24,"text":4626,"url":24,"identifiers":4627},"Siu, 2019, Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC, FASEB J, 33, 8865, 10.1096\u002Ffj.201802418R",{"doi":4628},"10.1096\u002Ffj.201802418R",{"id":24,"text":4630,"url":24,"identifiers":4631},"Shi, 2019, SARS-coronavirus open reading frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes, Cell Death Discov, 5, 101, 10.1038\u002Fs41420-019-0181-7",{"doi":4632},"10.1038\u002Fs41420-019-0181-7",{"id":24,"text":4634,"url":24,"identifiers":4635},"Duan, 2003, Clinical characteristics and mechanism of liver injury in patients with severe acute respiratory syndrome [in Chinese], Zhonghua Gan Zang Bing Za Zhi, 11, 493",{},{"id":24,"text":4637,"url":24,"identifiers":4638},"Wong, 2004, Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome, Clin Exp Immunol, 136, 95, 10.1111\u002Fj.1365-2249.2004.02415.x",{"doi":4639},"10.1111\u002Fj.1365-2249.2004.02415.x",{"id":24,"text":4641,"url":24,"identifiers":4642},"Ng, 2004, Inflammatory cytokine profile in children with severe acute respiratory syndrome, Pediatrics, 113, e7, 10.1542\u002Fpeds.113.1.e7",{"doi":4643},"10.1542\u002Fpeds.113.1.e7",{"id":24,"text":4645,"url":24,"identifiers":4646},"He, 2006, Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS, J Pathol, 210, 288, 10.1002\u002Fpath.2067",{"doi":4647},"10.1002\u002Fpath.2067",{"id":24,"text":4649,"url":24,"identifiers":4650},"Saccomanno, 2019, Predictors of effectiveness of anakinra in systemic juvenile idiopathic arthritis, J Rheumatol, 46, 416, 10.3899\u002Fjrheum.180331",{"doi":4651},"10.3899\u002Fjrheum.180331",{"id":24,"text":4653,"url":24,"identifiers":4654},"Sönmez, 2018, Anakinra treatment in macrophage activation syndrome: a single center experience and systemic review of literature, Clin Rheumatol, 37, 3329, 10.1007\u002Fs10067-018-4095-1",{"doi":4655},"10.1007\u002Fs10067-018-4095-1",{"id":24,"text":4657,"url":24,"identifiers":4658},"Salliot, 2009, Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials, Ann Rheum Dis, 68, 25, 10.1136\u002Fard.2007.083188",{"doi":4659},"10.1136\u002Fard.2007.083188",{"id":24,"text":4661,"url":24,"identifiers":4662},"Mehta, 2020, Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome, Lancet Rheumatol, 2, e358, 10.1016\u002FS2665-9913(20)30096-5",{"doi":4663},"10.1016\u002FS2665-9913(20)30096-5",{"id":24,"text":4665,"url":24,"identifiers":4666},"Monteagudo, 2020, Continuous intravenous anakinra infusion to calm the cytokine storm in macrophage activation syndrome, ACR Open Rheumatol, 2, 276, 10.1002\u002Facr2.11135",{"doi":4667},"10.1002\u002Facr2.11135",{"id":24,"text":4669,"url":24,"identifiers":4670},"Kullenberg, 2016, Long-term safety profile of anakinra in patients with severe cryopyrin-associated periodic syndromes, Rheumatology (Oxford), 55, 1499, 10.1093\u002Frheumatology\u002Fkew208",{"doi":4671},"10.1093\u002Frheumatology\u002Fkew208",{"id":24,"text":4673,"url":24,"identifiers":4674},"Klein, 2019, Long-term surveillance of biologic therapies in systemic-onset juvenile idiopathic arthritis: data from the German BIKER registry [manuscript published online ahead of print December 17, 2019], Rheumatology (Oxford)",{},{"id":24,"text":4676,"url":24,"identifiers":4677},"Mehta, 2020, COVID-19: consider cytokine storm syndromes and immunosuppression, Lancet, 395, 1033, 10.1016\u002FS0140-6736(20)30628-0",{"doi":4678},"10.1016\u002FS0140-6736(20)30628-0",{"id":24,"text":4680,"url":24,"identifiers":4681},"Shang, 2020, On the use of corticosteroids for 2019-nCoV pneumonia, Lancet, 395, 683, 10.1016\u002FS0140-6736(20)30361-5",{"doi":4682},"10.1016\u002FS0140-6736(20)30361-5",{"id":24,"text":4684,"url":24,"identifiers":4685},"Russell, 2020, Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury, Lancet, 395, 473, 10.1016\u002FS0140-6736(20)30317-2",{"doi":4686},"10.1016\u002FS0140-6736(20)30317-2",{"id":24,"text":4688,"url":24,"identifiers":4689},"Cain, 2017, Immune regulation by glucocorticoids, Nat Rev Immunol, 17, 233, 10.1038\u002Fnri.2017.1",{"doi":4690},"10.1038\u002Fnri.2017.1",{"id":24,"text":4692,"url":24,"identifiers":4693},"Ratman, 2013, How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering, Mol Cell Endocrinol, 380, 41, 10.1016\u002Fj.mce.2012.12.014",{"doi":4694},"10.1016\u002Fj.mce.2012.12.014",{"id":24,"text":4696,"url":24,"identifiers":4697},"Newton, 2017, Glucocorticoid and cytokine crosstalk: feedback, feedforward, and co-regulatory interactions determine repression or resistance, J Biol Chem, 292, 7163, 10.1074\u002Fjbc.R117.777318",{"doi":4698},"10.1074\u002Fjbc.R117.777318",{"id":24,"text":4700,"url":24,"identifiers":4701},"Rogatsky, 2006, Glucocorticoid modulation of cytokine signaling, Tissue Antigens, 68, 1, 10.1111\u002Fj.1399-0039.2006.00599.x",{"doi":4702},"10.1111\u002Fj.1399-0039.2006.00599.x",{"id":24,"text":4704,"url":24,"identifiers":4705},"Herold, 2006, Glucocorticoids in T cell apoptosis and function, Cell Mol Life Sci, 63, 60, 10.1007\u002Fs00018-005-5390-y",{"doi":4706},"10.1007\u002Fs00018-005-5390-y",{"id":24,"text":4708,"url":24,"identifiers":4709},"Lee, 2003, A major outbreak of severe acute respiratory syndrome in Hong Kong, N Engl J Med, 348, 1986, 10.1056\u002FNEJMoa030685",{"doi":4710},"10.1056\u002FNEJMoa030685",{"id":24,"text":4712,"url":24,"identifiers":4713},"Booth, 2003, Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area, JAMA, 289, 2801, 10.1001\u002Fjama.289.21.JOC30885",{"doi":4714},"10.1001\u002Fjama.289.21.JOC30885",{"id":24,"text":4716,"url":24,"identifiers":4717},"Lew, 2003, Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome, JAMA, 290, 374, 10.1001\u002Fjama.290.3.374",{"doi":4718},"10.1001\u002Fjama.290.3.374",{"id":24,"text":4720,"url":24,"identifiers":4721},"Peiris, 2003, Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study, Lancet, 361, 1767, 10.1016\u002FS0140-6736(03)13412-5",{"doi":4722},"10.1016\u002FS0140-6736(03)13412-5",{"id":24,"text":4724,"url":24,"identifiers":4725},"Lau, 2004, Outcome of coronavirus-associated severe acute respiratory syndrome using a standard treatment protocol, Respirology, 9, 173, 10.1111\u002Fj.1440-1843.2004.00588.x",{"doi":4726},"10.1111\u002Fj.1440-1843.2004.00588.x",{"id":24,"text":4728,"url":24,"identifiers":4729},"Sung, 2004, Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak, Thorax, 59, 414, 10.1136\u002Fthx.2003.014076",{"doi":4730},"10.1136\u002Fthx.2003.014076",{"id":24,"text":4732,"url":24,"identifiers":4733},"Yam, 2007, Corticosteroid treatment of severe acute respiratory syndrome in Hong Kong, J Infect, 54, 28, 10.1016\u002Fj.jinf.2006.01.005",{"doi":4734},"10.1016\u002Fj.jinf.2006.01.005",{"id":24,"text":4736,"url":24,"identifiers":4737},"Ho, 2003, High-dose pulse versus nonpulse corticosteroid regimens in severe acute respiratory syndrome, Am J Respir Crit Care Med, 168, 1449, 10.1164\u002Frccm.200306-766OC",{"doi":4738},"10.1164\u002Frccm.200306-766OC",{"id":24,"text":4740,"url":24,"identifiers":4741},"Chen, 2006, Treatment of severe acute respiratory syndrome with glucosteroids: the Guangzhou experience, Chest, 129, 1441, 10.1378\u002Fchest.129.6.1441",{"doi":4742},"10.1378\u002Fchest.129.6.1441",{"id":24,"text":4744,"url":24,"identifiers":4745},"Lee, 2004, Effects of early corticosteroid treatment on plasma SARS-associated coronavirus RNA concentrations in adult patients, J Clin Virol, 31, 304, 10.1016\u002Fj.jcv.2004.07.006",{"doi":4746},"10.1016\u002Fj.jcv.2004.07.006",{"id":24,"text":4748,"url":24,"identifiers":4749},"Stockman, 2006, SARS: systematic review of treatment effects, PLoS Med, 3, e343, 10.1371\u002Fjournal.pmed.0030343",{"doi":4750},"10.1371\u002Fjournal.pmed.0030343",{"id":24,"text":4752,"url":24,"identifiers":4753},"Guo, 2020, Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19), JAMA Cardiol, 5, 1, 10.1001\u002Fjamacardio.2020.1017",{"doi":4754},"10.1001\u002Fjamacardio.2020.1017",{"id":24,"text":4756,"url":24,"identifiers":4757},"Wu, 2020, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China, JAMA Intern Med, 180, 1, 10.1001\u002Fjamainternmed.2020.0994",{"doi":3719},{"id":24,"text":4759,"url":24,"identifiers":4760},"Fadel, 2020, Early short course corticosteroids in hospitalized patients with COVID-19 [manuscript published online ahead of print May 19, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa601",{"doi":4761},"10.1093\u002Fcid\u002Fciaa601",{"id":24,"text":4763,"url":24,"identifiers":4764},"Recovery Collaborative Group, 2020, Dexamethasone in hospitalized patients with Covid-19—preliminary report [manuscript published online ahead of print July 17, 2020], N Engl J Med",{},{"id":24,"text":4766,"url":24,"identifiers":4767},"Keller, 2020, Effect of systemic glucocorticoids on mortality or mechanical ventilation in patients with COVID-19, J Hosp Med, 10.12788\u002Fjhm.3497",{"doi":4768},"10.12788\u002Fjhm.3497",{"id":24,"text":4770,"url":24,"identifiers":4771},"Hazbun, 2020, The combination of tocilizumab and methylprednisolone along with initial lung recruitment strategy in coronavirus disease 2019 patients requiring mechanical ventilation: a series of 21 consecutive cases, Crit Care Explor, 2, e0145, 10.1097\u002FCCE.0000000000000145",{"doi":4772},"10.1097\u002FCCE.0000000000000145",{"id":24,"text":4774,"url":24,"identifiers":4775},"Callejas Rubio, 2020, Effectiveness of corticoid pulses in patients with cytokine storm syndrome induced by SARS-CoV-2 infection, Med Clin (Barc), 155, 159, 10.1016\u002Fj.medcli.2020.04.018",{"doi":4776},"10.1016\u002Fj.medcli.2020.04.018",{"id":24,"text":4778,"url":24,"identifiers":4779},"Arabi, 2018, Corticosteroid therapy for critically ill patients with Middle East respiratory syndrome, Am J Respir Crit Care Med, 197, 757, 10.1164\u002Frccm.201706-1172OC",{"doi":4780},"10.1164\u002Frccm.201706-1172OC",{"id":24,"text":4782,"url":24,"identifiers":4783},"Rowe, 2007, Corticosteroids for preventing relapse following acute exacerbations of asthma, Cochrane Database Syst Rev, 3, CD000195",{},{"id":24,"text":4785,"url":24,"identifiers":4786},"Benchimol, 2008, Traditional corticosteroids for induction of remission in Crohn’s disease, Cochrane Database Syst Rev, 2, CD006792",{},{"id":24,"text":4788,"url":24,"identifiers":4789},"El-Nawawy, 2017, Evaluation of early corticosteroid therapy in management of pediatric septic shock in pediatric intensive care patients: a randomized clinical study, Pediatr Infect Dis J, 36, 155, 10.1097\u002FINF.0000000000001380",{"doi":4790},"10.1097\u002FINF.0000000000001380",{"id":24,"text":4792,"url":24,"identifiers":4793},"Valoor, 2009, Low-dose hydrocortisone in pediatric septic shock: an exploratory study in a third world setting, Pediatr Crit Care Med, 10, 121, 10.1097\u002FPCC.0b013e3181936ab3",{"doi":4794},"10.1097\u002FPCC.0b013e3181936ab3",{"id":24,"text":4796,"url":24,"identifiers":4797},"Weiss, 2020, Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children, Pediatr Crit Care Med, 21, e52, 10.1097\u002FPCC.0000000000002198",{"doi":4798},"10.1097\u002FPCC.0000000000002198",{"id":24,"text":4800,"url":24,"identifiers":4801},"Rochwerg, 2018, Corticosteroids in sepsis: an updated systematic review and meta-analysis, Crit Care Med, 46, 1411, 10.1097\u002FCCM.0000000000003262",{"doi":4802},"10.1097\u002FCCM.0000000000003262",{"id":24,"text":4804,"url":24,"identifiers":4805},"Annane, 2019, Corticosteroids for treating sepsis in children and adults, Cochrane Database Syst Rev, 12, CD002243",{},{"id":24,"text":4807,"url":24,"identifiers":4808},"Annane, 2017, Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017, Crit Care Med, 45, 2078, 10.1097\u002FCCM.0000000000002737",{"doi":4809},"10.1097\u002FCCM.0000000000002737",{"id":24,"text":4811,"url":24,"identifiers":4812},"Hegenbarth, 2008, Preparing for pediatric emergencies: drugs to consider, Pediatrics, 121, 433, 10.1542\u002Fpeds.2007-3284",{"doi":4813},"10.1542\u002Fpeds.2007-3284",{"id":24,"text":4815,"url":24,"identifiers":4816},"Alhazzani, 2020, Surviving Sepsis Campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19), Intensive Care Med, 46, 854, 10.1007\u002Fs00134-020-06022-5",{"doi":4817},"10.1007\u002Fs00134-020-06022-5",{"id":24,"text":3444,"url":24,"identifiers":4819},{},{"id":24,"text":4821,"url":24,"identifiers":4822},"Parikh, 2017, Corticosteroid therapy and severity of vasogenic edema in posterior reversible encephalopathy syndrome, J Neurol Sci, 380, 11, 10.1016\u002Fj.jns.2017.06.044",{"doi":4823},"10.1016\u002Fj.jns.2017.06.044",{"id":24,"text":4825,"url":24,"identifiers":4826},"Hodgins, 2018, Steroid-induced psychosis in the pediatric population: a new case and review of the literature, J Child Adolesc Psychopharmacol, 28, 354, 10.1089\u002Fcap.2018.0017",{"doi":4827},"10.1089\u002Fcap.2018.0017",{"id":24,"text":4829,"url":24,"identifiers":4830},"Lee, 2004, Factors associated with psychosis among patients with severe acute respiratory syndrome: a case-control study, Clin Infect Dis, 39, 1247, 10.1086\u002F424016",{"doi":4831},"10.1086\u002F424016",{"id":24,"text":4833,"url":24,"identifiers":4834},"Hong, 2004, Avascular necrosis of bone in severe acute respiratory syndrome, Clin Radiol, 59, 602, 10.1016\u002Fj.crad.2003.12.008",{"doi":4835},"10.1016\u002Fj.crad.2003.12.008",{"id":24,"text":4837,"url":24,"identifiers":4838},"Lv, 2009, Avascular osteonecrosis after treatment of SARS: a 3-year longitudinal study, Trop Med Int Health, 14(, 79, 10.1111\u002Fj.1365-3156.2008.02187.x",{"doi":4839},"10.1111\u002Fj.1365-3156.2008.02187.x",{"id":24,"text":4841,"url":24,"identifiers":4842},"Zhao, 2017, Steroid therapy and the risk of osteonecrosis in SARS patients: a dose-response meta-analysis, Osteoporos Int, 28, 1027, 10.1007\u002Fs00198-016-3824-z",{"doi":4843},"10.1007\u002Fs00198-016-3824-z",{"id":24,"text":4845,"url":24,"identifiers":4846},"Liu, 2017, A 12-year follow-up study of combined treatment of post-severe acute respiratory syndrome patients with femoral head necrosis, Ther Clin Risk Manag, 13, 1449, 10.2147\u002FTCRM.S140694",{"doi":4847},"10.2147\u002FTCRM.S140694",{"id":24,"text":4849,"url":24,"identifiers":4850},"Chan, 2004, Osteonecrosis in children with severe acute respiratory syndrome, Pediatr Infect Dis J, 23, 888, 10.1097\u002F01.inf.0000137570.37856.ea",{"doi":4851},"10.1097\u002F01.inf.0000137570.37856.ea",{"id":24,"text":4853,"url":24,"identifiers":4854},"Lansbury, 2020, Corticosteroids as adjunctive therapy in the treatment of influenza: an updated Cochrane systematic review and meta-analysis, Crit Care Med, 48, e98, 10.1097\u002FCCM.0000000000004093",{"doi":4855},"10.1097\u002FCCM.0000000000004093",{"id":24,"text":4857,"url":24,"identifiers":4858},"Rutsaert, 2020, COVID-19-associated invasive pulmonary aspergillosis, Ann Intensive Care, 10, 71, 10.1186\u002Fs13613-020-00686-4",{"doi":4859},"10.1186\u002Fs13613-020-00686-4",{"id":24,"text":4861,"url":24,"identifiers":4862},"Koehler, 2020, COVID-19 associated pulmonary aspergillosis, Mycoses, 63, 528, 10.1111\u002Fmyc.13096",{"doi":4863},"10.1111\u002Fmyc.13096",{"id":24,"text":4865,"url":24,"identifiers":4866},"Thijs, 2019, Adrenal insufficiency, be aware of drug interactions!, Endocrinol Diabetes Metab Case Rep, 2019, 19-0062",{},{"id":24,"text":4868,"url":24,"identifiers":4869},"Bechman, 2019, A systematic review and meta-analysis of infection risk with small molecule JAK inhibitors in rheumatoid arthritis, Rheumatology (Oxford), 58, 1755, 10.1093\u002Frheumatology\u002Fkez087",{"doi":4870},"10.1093\u002Frheumatology\u002Fkez087",{"id":24,"text":4872,"url":24,"identifiers":4873},"Morris, 2018, The molecular details of cytokine signaling via the JAK\u002FSTAT pathway, Protein Sci, 27, 1984, 10.1002\u002Fpro.3519",{"doi":4874},"10.1002\u002Fpro.3519",{"id":24,"text":4876,"url":24,"identifiers":4877},"O’Shea, 2013, Back to the future: oral targeted therapy for RA and other autoimmune diseases, Nat Rev Rheumatol, 9, 173, 10.1038\u002Fnrrheum.2013.7",{"doi":4878},"10.1038\u002Fnrrheum.2013.7",{"id":24,"text":4880,"url":24,"identifiers":4881},"Huang, 2019, Tofacitinib treatment of refractory systemic juvenile idiopathic arthritis, Pediatrics, 143, e20182845, 10.1542\u002Fpeds.2018-2845",{"doi":4882},"10.1542\u002Fpeds.2018-2845",{"id":24,"text":4884,"url":24,"identifiers":4885},"Kerrigan, 2018, JAK inhibitors in rheumatology: implications for paediatric syndromes?, Curr Rheumatol Rep, 20, 83, 10.1007\u002Fs11926-018-0792-7",{"doi":4886},"10.1007\u002Fs11926-018-0792-7",{"id":24,"text":4888,"url":24,"identifiers":4889},"González Vicent, 2019, Ruxolitinib treatment for steroid refractory acute and chronic graft vs host disease in children: clinical and immunological results, Am J Hematol, 94, 319, 10.1002\u002Fajh.25376",{"doi":4890},"10.1002\u002Fajh.25376",{"id":24,"text":4892,"url":24,"identifiers":4893},"Khandelwal, 2017, Ruxolitinib as salvage therapy in steroid-refractory acute graft-versus-host disease in pediatric hematopoietic stem cell transplant patients, Biol Blood Marrow Transplant, 23, 1122, 10.1016\u002Fj.bbmt.2017.03.029",{"doi":4894},"10.1016\u002Fj.bbmt.2017.03.029",{"id":24,"text":4896,"url":24,"identifiers":4897},"Ahmed, 2019, Ruxolitinib in adult patients with secondary haemophagocytic lymphohistiocytosis: an open-label, single-centre, pilot trial, Lancet Haematol, 6, e630, 10.1016\u002FS2352-3026(19)30156-5",{"doi":4898},"10.1016\u002FS2352-3026(19)30156-5",{"id":24,"text":4900,"url":24,"identifiers":4901},"Sin, 2019, Ruxolitinib for secondary hemophagocytic lymphohistiocytosis: first case report, Hematol Oncol Stem Cell Ther, 12, 166, 10.1016\u002Fj.hemonc.2017.07.002",{"doi":4902},"10.1016\u002Fj.hemonc.2017.07.002",{"id":24,"text":4904,"url":24,"identifiers":4905},"Broglie, 2017, Ruxolitinib for treatment of refractory hemophagocytic lymphohistiocytosis, Blood Adv, 1, 1533, 10.1182\u002Fbloodadvances.2017007526",{"doi":4906},"10.1182\u002Fbloodadvances.2017007526",{"id":24,"text":4908,"url":24,"identifiers":4909},"Trantham, 2020, Ruxolitinib for the treatment of lymphoma-associated hemophagocytic lymphohistiocytosis: a cautionary tale, J Oncol Pharm Pract, 26, 1005, 10.1177\u002F1078155219878774",{"doi":4910},"10.1177\u002F1078155219878774",{"id":24,"text":4912,"url":24,"identifiers":4913},"Cao, 2020, Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): a multicenter, single-blind, randomized controlled trial, J Allergy Clin Immunol, 146, 137, 10.1016\u002Fj.jaci.2020.05.019",{"doi":4914},"10.1016\u002Fj.jaci.2020.05.019",{"id":24,"text":4916,"url":24,"identifiers":4917},"Titanji, 2020, Use of baricitinib in patients with moderate and severe COVID-19 [published online ahead of print June 29, 2020], Clin Infect Dis",{},{"id":24,"text":4919,"url":24,"identifiers":4920},"Cantini, 2020, Beneficial impact of baricitinib in COVID-19 moderate pneumonia; multicentre study [published online ahead of print June 24, 2020], J Infect, 10.1016\u002Fj.jinf.2020.06.052",{"doi":4921},"10.1016\u002Fj.jinf.2020.06.052",{"id":24,"text":4923,"url":24,"identifiers":4924},"Colombel, 2018, Herpes zoster in patients receiving JAK inhibitors for ulcerative colitis: mechanism, epidemiology, management, and prevention, Inflamm Bowel Dis, 24, 2173, 10.1093\u002Fibd\u002Fizy150",{"doi":4925},"10.1093\u002Fibd\u002Fizy150",{"id":24,"text":4927,"url":24,"identifiers":4928},"Richardson, 2020, Baricitinib for COVID-19: a suitable treatment? Authors’ reply [manuscript published online ahead of print April 2, 2020], Lancet Infect Dis, 10.1016\u002FS1473-3099(20)30270-X",{"doi":4929},"10.1016\u002FS1473-3099(20)30270-X",{"id":24,"text":4931,"url":24,"identifiers":4932},"He, 2013, Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskelet Disord, 14, 298, 10.1186\u002F1471-2474-14-298",{"doi":4933},"10.1186\u002F1471-2474-14-298",{"id":24,"text":4935,"url":24,"identifiers":4936},"Gaspari, 2020, Side effects of ruxolitinib in patients with SARS-CoV-2 infection: two case reports, Int J Antimicrob Agents, 56, 106023, 10.1016\u002Fj.ijantimicag.2020.106023",{"doi":4937},"10.1016\u002Fj.ijantimicag.2020.106023",{"id":24,"text":4939,"url":24,"identifiers":4940},"Middeldorp, 2020, Incidence of venous thromboembolism in hospitalized patients with COVID-19, J Thromb Haemost, 18, 1995, 10.1111\u002Fjth.14888",{"doi":4941},"10.1111\u002Fjth.14888",{"id":24,"text":4475,"url":24,"identifiers":4943},{},{"id":24,"text":4945,"url":24,"identifiers":4946},"Veeravalli, 2020, Critical assessment of pharmacokinetic drug-drug interaction potential of tofacitinib, baricitinib and upadacitinib, the three approved Janus kinase inhibitors for rheumatoid arthritis treatment, Drug Saf, 43, 711, 10.1007\u002Fs40264-020-00938-z",{"doi":4947},"10.1007\u002Fs40264-020-00938-z",{"id":24,"text":4949,"url":24,"identifiers":4950},"Casadevall, 2020, The convalescent sera option for containing COVID-19, J Clin Invest, 130, 1545, 10.1172\u002FJCI138003",{"doi":4951},"10.1172\u002FJCI138003",{"id":24,"text":4953,"url":24,"identifiers":4954},"Cheng, 2005, Use of convalescent plasma therapy in SARS patients in Hong Kong, Eur J Clin Microbiol Infect Dis, 24, 44, 10.1007\u002Fs10096-004-1271-9",{"doi":4955},"10.1007\u002Fs10096-004-1271-9",{"id":24,"text":4957,"url":24,"identifiers":4958},"Soo, 2004, Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients, Clin Microbiol Infect, 10, 676, 10.1111\u002Fj.1469-0691.2004.00956.x",{"doi":4959},"10.1111\u002Fj.1469-0691.2004.00956.x",{"id":24,"text":4961,"url":24,"identifiers":4962},"Ko, 2018, Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience, Antivir Ther, 23, 617, 10.3851\u002FIMP3243",{"doi":4963},"10.3851\u002FIMP3243",{"id":24,"text":4965,"url":24,"identifiers":4966},"Mair-Jenkins, 2015, The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis, J Infect Dis, 211, 80, 10.1093\u002Finfdis\u002Fjiu396",{"doi":4967},"10.1093\u002Finfdis\u002Fjiu396",{"id":24,"text":4969,"url":24,"identifiers":4970},"Shen, 2020, Treatment of 5 critically ill patients with COVID-19 with convalescent plasma, JAMA, 323, 1582, 10.1001\u002Fjama.2020.4783",{"doi":4971},"10.1001\u002Fjama.2020.4783",{"id":24,"text":4973,"url":24,"identifiers":4974},"Zhang, 2020, Treatment with convalescent plasma for critically ill patients with SARS-CoV-2 infection, Chest, 158, e9, 10.1016\u002Fj.chest.2020.03.039",{"doi":4975},"10.1016\u002Fj.chest.2020.03.039",{"id":24,"text":4977,"url":24,"identifiers":4978},"Duan, 2020, Effectiveness of convalescent plasma therapy in severe COVID-19 patients, Proc Natl Acad Sci U S A, 117, 9490, 10.1073\u002Fpnas.2004168117",{"doi":4979},"10.1073\u002Fpnas.2004168117",{"id":24,"text":4981,"url":24,"identifiers":4982},"Ahn, 2020, Use of convalescent plasma therapy in two COVID-19 patients with acute respiratory distress syndrome in Korea, J Korean Med Sci, 35, e149, 10.3346\u002Fjkms.2020.35.e149",{"doi":4983},"10.3346\u002Fjkms.2020.35.e149",{"id":24,"text":4985,"url":24,"identifiers":4986},"Ye, 2020, Treatment with convalescent plasma for COVID-19 patients in Wuhan, China [manuscript published online ahead of print April 15, 2020], J Med Virol, 10.1002\u002Fjmv.25882",{"doi":4987},"10.1002\u002Fjmv.25882",{"id":24,"text":4989,"url":24,"identifiers":4990},"Li, 2020, Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial, JAMA, 324, 1, 10.1001\u002Fjama.2020.10044",{"doi":4991},"10.1001\u002Fjama.2020.10044",{"id":24,"text":4993,"url":24,"identifiers":4994},"Qu, 2020, Profile of IgG and IgM antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [manuscript published online ahead of print April 27, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa489",{"doi":4995},"10.1093\u002Fcid\u002Fciaa489",{"id":24,"text":4997,"url":24,"identifiers":4998},"Long, 2020, Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections, Nat Med, 26, 1200, 10.1038\u002Fs41591-020-0965-6",{"doi":4999},"10.1038\u002Fs41591-020-0965-6",{"id":24,"text":5001,"url":24,"identifiers":5002},"Zhang, 2020, Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19, Aging (Albany NY), 12, 6536, 10.18632\u002Faging.103102",{"doi":5003},"10.18632\u002Faging.103102",{"id":24,"text":5005,"url":24,"identifiers":5006},"Zeng, 2020, Effect of convalescent plasma therapy on viral shedding and survival in COVID-19 patients, J Infect Dis, 222, 38, 10.1093\u002Finfdis\u002Fjiaa228",{"doi":5007},"10.1093\u002Finfdis\u002Fjiaa228",{"id":24,"text":3342,"url":24,"identifiers":5009},{},{"id":24,"text":5011,"url":24,"identifiers":5012},"Figlerowicz, 2020, First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia [manuscript published online ahead of print July 1, 2020], Transfus Apher Sci, 10.1016\u002Fj.transci.2020.102866",{"doi":5013},"10.1016\u002Fj.transci.2020.102866",{"id":24,"text":5015,"url":24,"identifiers":5016},"Wan, 2020, Molecular mechanism for antibody-dependent enhancement of coronavirus entry, J Virol, 94:e02015-19",{},{"id":24,"text":5018,"url":24,"identifiers":5019},"Food and Drug Administration",{},{"id":24,"text":5021,"url":24,"identifiers":5022},"Liu, 2019, Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection, JCI Insight, 4, e123158, 10.1172\u002Fjci.insight.123158",{"doi":5023},"10.1172\u002Fjci.insight.123158",{"id":24,"text":5025,"url":24,"identifiers":5026},"Crowe, 2001, Passively acquired antibodies suppress humoral but not cell-mediated immunity in mice immunized with live attenuated respiratory syncytial virus vaccines, J Immunol, 167, 3910, 10.4049\u002Fjimmunol.167.7.3910",{"doi":5027},"10.4049\u002Fjimmunol.167.7.3910",{"id":24,"text":5029,"url":24,"identifiers":5030},"Murphy, 1986, Serum and nasal-wash immunoglobulin G and A antibody response of infants and children to respiratory syncytial virus F and G glycoproteins following primary infection, J Clin Microbiol, 23, 1009, 10.1128\u002FJCM.23.6.1009-1014.1986",{"doi":5031},"10.1128\u002FJCM.23.6.1009-1014.1986",{"id":24,"text":5033,"url":24,"identifiers":5034},"Bloch, 2020, Deployment of convalescent plasma for the prevention and treatment of COVID-19, J Clin Invest, 130, 2757, 10.1172\u002FJCI138745",{"doi":5035},"10.1172\u002FJCI138745",{"id":24,"text":5037,"url":24,"identifiers":5038},"Díez, 2020, Currently available intravenous immunoglobulin contains antibodies reacting against severe acute respiratory syndrome coronavirus 2 antigens, Immunotherapy, 12, 571, 10.2217\u002Fimt-2020-0095",{"doi":5039},"10.2217\u002Fimt-2020-0095",{"id":24,"text":5041,"url":24,"identifiers":5042},"Samuelsson, 2001, Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor, Science, 291, 484, 10.1126\u002Fscience.291.5503.484",{"doi":5043},"10.1126\u002Fscience.291.5503.484",{"id":24,"text":5045,"url":24,"identifiers":5046},"Siedlar, 2011, Preparations of intravenous immunoglobulins diminish the number and proinflammatory response of CD14+CD16++ monocytes in common variable immunodeficiency (CVID) patients, Clin Immunol, 139, 122, 10.1016\u002Fj.clim.2011.01.002",{"doi":5047},"10.1016\u002Fj.clim.2011.01.002",{"id":24,"text":5049,"url":24,"identifiers":5050},"Othy, 2013, Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis, J Immunol, 190, 4535, 10.4049\u002Fjimmunol.1201965",{"doi":5051},"10.4049\u002Fjimmunol.1201965",{"id":24,"text":5053,"url":24,"identifiers":5054},"Perez, 2017, Update on the use of immunoglobulin in human disease: a review of evidence, J Allergy Clin Immunol, 139, S1, 10.1016\u002Fj.jaci.2016.09.023",{"doi":5055},"10.1016\u002Fj.jaci.2016.09.023",{"id":24,"text":5057,"url":24,"identifiers":5058},"Wohlfarth, 2019, Interleukin 1 receptor antagonist anakinra, intravenous immunoglobulin, and corticosteroids in the management of critically ill adult patients with hemophagocytic lymphohistiocytosis, J Intensive Care Med, 34, 723, 10.1177\u002F0885066617711386",{"doi":5059},"10.1177\u002F0885066617711386",{"id":24,"text":5061,"url":24,"identifiers":5062},"Yang, 2005, Thrombocytopenia in patients with severe acute respiratory syndrome (review), Hematology, 10, 101, 10.1080\u002F10245330400026170",{"doi":5063},"10.1080\u002F10245330400026170",{"id":24,"text":5065,"url":24,"identifiers":5066},"Van Dyne, 2019, Incidence and outcome of severe and nonsevere thrombocytopenia associated with Zika virus infection—Puerto Rico, 2016, Open Forum Infect Dis, 6, ofy325, 10.1093\u002Fofid\u002Fofy325",{"doi":5067},"10.1093\u002Fofid\u002Fofy325",{"id":24,"text":5069,"url":24,"identifiers":5070},"Lippi, 2020, Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis, Clin Chim Acta, 506, 145, 10.1016\u002Fj.cca.2020.03.022",{"doi":5071},"10.1016\u002Fj.cca.2020.03.022",{"id":24,"text":5073,"url":24,"identifiers":5074},"Sen, 2016, Macrophage activation syndrome, Indian J Pediatr, 83, 248, 10.1007\u002Fs12098-015-1877-1",{"doi":5075},"10.1007\u002Fs12098-015-1877-1",{"id":24,"text":5077,"url":24,"identifiers":5078},"Cao, 2020, High-dose intravenous immunoglobulin as a therapeutic option for deteriorating patients with coronavirus disease 2019, Open Forum Infect Dis, 7, ofaa102, 10.1093\u002Fofid\u002Fofaa102",{"doi":5079},"10.1093\u002Fofid\u002Fofaa102",{"id":24,"text":5081,"url":24,"identifiers":5082},"McNab, 2015, Type I interferons in infectious disease, Nat Rev Immunol, 15, 87, 10.1038\u002Fnri3787",{"doi":5083},"10.1038\u002Fnri3787",{"id":24,"text":5085,"url":24,"identifiers":5086},"Ye, 2019, Interferon-λ orchestrates innate and adaptive mucosal immune responses, Nat Rev Immunol, 19, 614, 10.1038\u002Fs41577-019-0182-z",{"doi":5087},"10.1038\u002Fs41577-019-0182-z",{"id":24,"text":5089,"url":24,"identifiers":5090},"Prokunina-Olsson, 2020, COVID-19 and emerging viral infections: the case for interferon lambda, J Exp Med, 217, e20200653, 10.1084\u002Fjem.20200653",{"doi":5091},"10.1084\u002Fjem.20200653",{"id":24,"text":5093,"url":24,"identifiers":5094},"Muir, 2014, A randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection, J Hepatol, 61, 1238, 10.1016\u002Fj.jhep.2014.07.022",{"doi":5095},"10.1016\u002Fj.jhep.2014.07.022",{"id":24,"text":5097,"url":24,"identifiers":5098},"Agarwal, 2018, 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection, J Hepatol, 68, 672, 10.1016\u002Fj.jhep.2017.11.039",{"doi":5099},"10.1016\u002Fj.jhep.2017.11.039",{"id":24,"text":5101,"url":24,"identifiers":5102},"Korean Association for the Study of the Liver., 2019, KASL clinical practice guidelines for management of chronic hepatitis B, Clin Mol Hepatol, 25, 93, 10.3350\u002Fcmh.2019.1002",{"doi":5103},"10.3350\u002Fcmh.2019.1002",{"id":24,"text":5105,"url":24,"identifiers":5106},"Chu, 2020, Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 [manuscript published online ahead of print April 9, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa410",{"doi":5107},"10.1093\u002Fcid\u002Fciaa410",{"id":24,"text":5109,"url":24,"identifiers":5110},"O’Brien, 2020, Weak induction of interferon expression by SARS-CoV-2 supports clinical trials of interferon lambda to treat early COVID-19 [manuscript published online ahead of print April 17, 2020], Clin Infect Dis, 10.1093\u002Fcid\u002Fciaa453",{"doi":5111},"10.1093\u002Fcid\u002Fciaa453",{"id":24,"text":5113,"url":24,"identifiers":5114},"Hung, 2020, Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial, Lancet, 395, 1695, 10.1016\u002FS0140-6736(20)31042-4",{"doi":5115},"10.1016\u002FS0140-6736(20)31042-4",{"id":24,"text":5117,"url":24,"identifiers":5118},"Gaeta, 2002, Premature discontinuation of interferon plus ribavirin for adverse effects: a multicentre survey in ‘real world’ patients with chronic hepatitis C, Aliment Pharmacol Ther, 16, 1633, 10.1046\u002Fj.1365-2036.2002.01331.x",{"doi":5119},"10.1046\u002Fj.1365-2036.2002.01331.x",{"id":24,"text":5121,"url":24,"identifiers":5122},"Raison, 2005, Neuropsychiatric adverse effects of interferon-alpha: recognition and management, CNS Drugs, 19, 105, 10.2165\u002F00023210-200519020-00002",{"doi":5123},"10.2165\u002F00023210-200519020-00002",{"id":24,"text":5125,"url":24,"identifiers":5126},"Planet, 2016, Lambda interferon restructures the nasal microbiome and increases susceptibility to Staphylococcus aureus superinfection, mBio, 7, e01939, 10.1128\u002FmBio.01939-15",{"doi":5127},"10.1128\u002FmBio.01939-15",{"id":24,"text":5129,"url":24,"identifiers":5130},"Davidson, 2015, Disease-promoting effects of type I interferons in viral, bacterial, and coinfections, J Interferon Cytokine Res, 35, 252, 10.1089\u002Fjir.2014.0227",{"doi":5131},"10.1089\u002Fjir.2014.0227",{"id":24,"text":5133,"url":24,"identifiers":5134},"Locatelli, 2020, Emapalumab in children with primary hemophagocytic lymphohistiocytosis, N Engl J Med, 382, 1811, 10.1056\u002FNEJMoa1911326",{"doi":5135},"10.1056\u002FNEJMoa1911326",{"id":5137,"createTime":5138,"updateTime":5138,"relativeEntities":5139,"slug":5140,"properties":5141,"entityType":141,"verifyStatus":142,"verifyTime":5138,"verifyNote":143,"syncStatus":23,"languages":5157,"translateLanguages":24,"viewCount":25,"primaryUrl":5158,"fullTextUrl":24,"authors":5159,"publicationType":398,"publisherRelationship":5445,"citationCount":3069,"citationInfo":5477,"publishDate":5479,"publishYear":5480,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":24,"openAccess":24,"references":5481,"isForceReanalyzing":462},"2a333fe2-fa03-45f8-a06b-485b13d4197c","2025-02-06T04:24:40.170+00:00",[],"A-Multicenter-Consortium-to-Define-the-Epidemiology-and-Outcomes-of-Pediatric-Solid-Organ-Transplant-Recipients-With-Inpatient-Respiratory-Virus-Infection",{"mag":5142,"keywords":5144,"pmc":5145,"openalex":5147,"abstract":5149,"title":5151,"pm":5153,"doi":5155},{"VOID":5143},"2789425479",{},{"VOID":5146},"7107524",{"VOID":5148},"W2789425479",{"EN":5150},"\u003Cjats:title>Abstract\u003C\u002Fjats:title>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Background\u003C\u002Fjats:title>\n                  \u003Cjats:p>Respiratory virus infection (RVI) in pediatric solid organ transplant (SOT) recipients poses a significant risk; however, the epidemiology and effects of an RVI after pediatric SOT in the era of current molecular diagnostic assays are unclear.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Methods\u003C\u002Fjats:title>\n                  \u003Cjats:p>A retrospective observational cohort of pediatric SOT recipients (January 2010 to June 2013) was assembled from 9 US pediatric transplant centers. Charts were reviewed for RVI events associated with hospitalization within 1 year after the transplant. An RVI diagnosis required respiratory symptoms and detection of a virus (ie, human rhinovirus\u002Fenterovirus, human metapneumovirus, influenza virus, parainfluenza virus, coronavirus, and\u002For respiratory syncytial virus). The incidence of RVI was calculated, and the association of baseline SOT factors with subsequent pulmonary complications and death was assessed.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Results\u003C\u002Fjats:title>\n                  \u003Cjats:p>Of 1096 pediatric SOT recipients (448 liver, 289 kidney, 251 heart, 66 lung, 42 intestine\u002Fmultivisceral), 159 (14.5%) developed RVI associated with hospitalization within 12 months after their transplant. RVI occurred at the highest rates in intestine\u002Fabdominal multivisceral (38%), thoracic (heart\u002Flung) (18.6%), and liver (15.6%) transplant recipients and a lower rate in kidney (5.5%) transplant recipients. RVI was associated with younger median age at transplant (1.72 vs 7.89 years; P < .001) and among liver or kidney transplant recipients with the receipt of a deceased-donor graft compared to a living donor (P = .01). The all-cause and attributable case-fatality rates within 3 months of RVI onset were 4% and 0%, respectively. Multivariable logistic regression models revealed that age was independently associated with increased risk for a pulmonary complication (odds ratio, 1.24 [95% confidence interval, 1.02–1.51]) and that receipt of an intestine\u002Fmultivisceral transplant was associated with increased risk of all-cause death (odds ratio, 24.54 [95% confidence interval, 1.69–327.96]).\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>\n               \u003Cjats:sec>\n                  \u003Cjats:title>Conclusions\u003C\u002Fjats:title>\n                  \u003Cjats:p>In this study, hospital-associated RVI was common in the first year after pediatric SOT and associated with younger age at transplant. All-cause death after RVI was rare, and no definitive attributable death occurred.\u003C\u002Fjats:p>\n               \u003C\u002Fjats:sec>",{"EN":5152},"A Multicenter Consortium to Define the Epidemiology and Outcomes of Pediatric Solid Organ Transplant Recipients With Inpatient Respiratory Virus Infection",{"VOID":5154},"29538674",{"VOID":5156},"10.1093\u002Fjpids\u002Fpiy024",[145],"https:\u002F\u002Facademic.oup.com\u002Fjpids\u002Farticle\u002F8\u002F3\u002F197\u002F4925905",[5160,5179,5198,5219,5236,5257,5279,5296,5338,5355,5376,5397,5411,5428],{"id":5161,"sortIndex":62,"researcher":24,"roles":5162,"affiliations":5163,"properties":5174},"219da50a-4d4a-4b57-a1af-d778b820733d",[],[5164],{"id":5165,"sortIndex":25,"affiliation":5166,"properties":24},"516670ba-88fa-472f-87f0-53e977db93a7",{"id":5167,"createTime":5168,"updateTime":5168,"relativeEntities":5169,"slug":5170,"properties":5171,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"e0872d5f-b5ed-415c-87bc-8a217a40ccb2","2025-02-06T04:24:40.223+00:00",[],"Department-of-Pediatrics-Section-of-Infectious-Diseases-Texas-Children-s-Hospital-Baylor-College-of-Medicine-Houston",{"title":5172},{"EN":5173},"Department of Pediatrics, Section of Infectious Diseases, Texas Children's Hospital, Baylor College of Medicine, Houston",{"openalex":5175,"title":5177},{"VOID":5176},"A5110309252",{"EN":5178},"Leigh R. Sweet",{"id":5180,"sortIndex":150,"researcher":24,"roles":5181,"affiliations":5182,"properties":5193},"09539b9b-2482-429f-8ffd-e0b2343a7638",[],[5183],{"id":5184,"sortIndex":25,"affiliation":5185,"properties":24},"d4e9c274-8635-491f-8c7f-d774d781b381",{"id":5186,"createTime":5187,"updateTime":5187,"relativeEntities":5188,"slug":5189,"properties":5190,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"bd86ad53-8aeb-4b67-99a9-1f84d6b3c691","2025-02-06T04:24:40.184+00:00",[],"Seattle-Children-s-Research-Institute-Seattle-Children-s-Hospital-and-University-of-Washington",{"title":5191},{"EN":5192},"Seattle Children's Research Institute, Seattle Children's Hospital, and University of Washington",{"openalex":5194,"title":5196},{"VOID":5195},"A5036747735",{"EN":5197},"Alastair Murray",{"id":5199,"sortIndex":166,"researcher":24,"roles":5200,"affiliations":5201,"properties":5212},"208ac3dc-31db-4856-904a-6d8d102cf9a9",[],[5202],{"id":5203,"sortIndex":25,"affiliation":5204,"properties":24},"d62adc7a-b532-40b0-8edd-21e0daa0d0f3",{"id":5205,"createTime":5206,"updateTime":5206,"relativeEntities":5207,"slug":5208,"properties":5209,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"b46879f5-0cbe-4d02-b9ad-4b67d2f9d230","2025-02-06T04:24:40.212+00:00",[],"Departments-of-Pediatrics-and-Molecular-Genetics-and-Microbiology-Duke-University-Durham-North-Carolina",{"title":5210},{"EN":5211},"Departments of Pediatrics and Molecular Genetics and Microbiology, Duke University, Durham, North Carolina",{"openalex":5213,"orcid":5215,"title":5217},{"VOID":5214},"A5056810823",{"VOID":5216},"https:\u002F\u002Forcid.org\u002F0000-0002-5446-1094",{"EN":5218},"William J. Steinbach",{"id":5220,"sortIndex":233,"researcher":24,"roles":5221,"affiliations":5222,"properties":5229},"af466be4-ad2c-4e18-b637-e9d698e814a3",[],[5223],{"id":5224,"sortIndex":25,"affiliation":5225,"properties":24},"5b86a4a7-4e91-4470-947e-ebdeacff85bc",{"id":5167,"createTime":5168,"updateTime":5168,"relativeEntities":5226,"slug":5170,"properties":5227,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":5228},{"EN":5173},{"openalex":5230,"orcid":5232,"title":5234},{"VOID":5231},"A5024481017",{"VOID":5233},"https:\u002F\u002Forcid.org\u002F0000-0002-0457-7689",{"EN":5235},"Flor M. Muñoz",{"id":5237,"sortIndex":294,"researcher":24,"roles":5238,"affiliations":5239,"properties":5250},"91e1c565-5822-4289-abf7-9051432f335e",[],[5240],{"id":5241,"sortIndex":25,"affiliation":5242,"properties":24},"812bd913-87fd-4edd-8576-96961e9e380f",{"id":5243,"createTime":5244,"updateTime":5244,"relativeEntities":5245,"slug":5246,"properties":5247,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"c168a410-1888-4df7-9b22-d6d7a594cbae","2025-02-06T04:24:40.273+00:00",[],"Division-of-Infectious-Diseases-Children-s-Hospital-of-Pittsburgh-of-UPMC-and-Departments-of-Pediatrics-and-Surgery-University-of-Pittsburgh-School-of-Medicine-Pennsylvania",{"title":5248},{"EN":5249},"Division of Infectious Diseases, Children's Hospital of Pittsburgh of UPMC, and Departments of Pediatrics and Surgery, University of Pittsburgh School of Medicine, Pennsylvania",{"openalex":5251,"orcid":5253,"title":5255},{"VOID":5252},"A5070892473",{"VOID":5254},"https:\u002F\u002Forcid.org\u002F0000-0002-2556-0544",{"EN":5256},"Marian G. Michaels",{"id":5258,"sortIndex":706,"researcher":24,"roles":5259,"affiliations":5260,"properties":5272},"97d7ada0-4c63-4d3f-93f6-da7014cb1820",[],[5261],{"id":5262,"sortIndex":25,"affiliation":5263,"properties":24},"8f5632d0-68cd-4b0f-b9b3-353823be540c",{"id":5264,"createTime":5265,"updateTime":5266,"relativeEntities":5267,"slug":5268,"properties":5269,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"53212041-b06c-4980-b8d4-ccedb7df7c23","2024-10-12T21:58:42.069+00:00","2025-02-06T04:24:40.233+00:00",[],"Department-of-Pediatrics-Albert-Einstein-College-of-Medicine-and-Children-s-Hospital-at-Montefiore-Bronx-New-York-",{"title":5270},{"EN":5271},"Department of Pediatrics, Albert Einstein College of Medicine and Children's Hospital at Montefiore, Bronx, New York.",{"openalex":5273,"orcid":5275,"title":5277},{"VOID":5274},"A5025731778",{"VOID":5276},"https:\u002F\u002Forcid.org\u002F0000-0001-9974-0786",{"EN":5278},"Betsy C. Herold",{"id":5280,"sortIndex":272,"researcher":24,"roles":5281,"affiliations":5282,"properties":5289},"06a5497c-f146-450e-bcee-9e7ffcb406e8",[],[5283],{"id":5284,"sortIndex":25,"affiliation":5285,"properties":24},"9627f298-d51d-4a92-aee0-fb84e8fb64af",{"id":5186,"createTime":5187,"updateTime":5187,"relativeEntities":5286,"slug":5189,"properties":5287,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":5288},{"EN":5192},{"openalex":5290,"orcid":5292,"title":5294},{"VOID":5291},"A5070328573",{"VOID":5293},"https:\u002F\u002Forcid.org\u002F0000-0003-1134-4178",{"EN":5295},"Janet A. Englund",{"id":5297,"sortIndex":508,"researcher":24,"roles":5298,"affiliations":5299,"properties":5331},"ab14c6a9-6788-4dc6-92ee-f2c78d6e9b02",[],[5300,5311,5321],{"id":5301,"sortIndex":209,"affiliation":5302,"properties":24},"46c42ca0-f34e-44d5-a46f-bef6a6614c36",{"id":5303,"createTime":5304,"updateTime":5305,"relativeEntities":5306,"slug":5307,"properties":5308,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"03d25ea9-84b8-47d0-aef1-bd14e155a664","2025-02-06T04:24:40.253+00:00","2025-06-11T17:08:09.532+00:00",[],"Division-of-Infectious-Diseases-Department-of-Pediatrics-Pennsylvania",{"title":5309},{"EN":5310},"Division of Infectious Diseases, Department of Pediatrics, Pennsylvania",{"id":5312,"sortIndex":25,"affiliation":5313,"properties":24},"dca43989-a026-4b5d-9adc-7cd88e46ff26",{"id":5314,"createTime":5315,"updateTime":5315,"relativeEntities":5316,"slug":5317,"properties":5318,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"1f958707-721e-4d4d-bdfd-e3e5fd2705e0","2025-02-06T04:24:40.243+00:00",[],"Center-for-Clinical-Epidemiology-and-Biostatistics-Perelman-School-of-Medicine-University-of-Pennsylvania-Philadelphia",{"title":5319},{"EN":5320},"Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia",{"id":5322,"sortIndex":166,"affiliation":5323,"properties":24},"562a6bb7-95b8-41fb-b07f-c8ec9c626208",{"id":5324,"createTime":5325,"updateTime":5325,"relativeEntities":5326,"slug":5327,"properties":5328,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"bf603953-6654-49e2-9898-a7ae9c7201be","2025-02-06T04:24:40.247+00:00",[],"Center-for-Pediatric-Clinical-Effectiveness-Children-s-Hospital-of-Philadelphia-Pennsylvania",{"title":5329},{"EN":5330},"Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Pennsylvania",{"openalex":5332,"orcid":5334,"title":5336},{"VOID":5333},"A5055721856",{"VOID":5335},"https:\u002F\u002Forcid.org\u002F0000-0002-8224-4281",{"EN":5337},"Brian T. Fisher",{"id":5339,"sortIndex":620,"researcher":24,"roles":5340,"affiliations":5341,"properties":5348},"442c0600-4102-435c-b8b4-2bb0ecf5a85c",[],[5342],{"id":5343,"sortIndex":25,"affiliation":5344,"properties":24},"9aed1ca9-6fd3-40a9-a6e9-99d0fa9788b8",{"id":5264,"createTime":5265,"updateTime":5266,"relativeEntities":5345,"slug":5268,"properties":5346,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":5347},{"EN":5271},{"openalex":5349,"orcid":5351,"title":5353},{"VOID":5350},"A5020791854",{"VOID":5352},"https:\u002F\u002Forcid.org\u002F0000-0002-7968-8287",{"EN":5354},"Rebecca Pellett Madan",{"id":5356,"sortIndex":185,"researcher":24,"roles":5357,"affiliations":5358,"properties":5369},"7537eee0-47f7-4d27-9d89-3725e8929777",[],[5359],{"id":5360,"sortIndex":25,"affiliation":5361,"properties":24},"c215fc42-b5df-470b-beca-5748dda627cc",{"id":5362,"createTime":5363,"updateTime":5363,"relativeEntities":5364,"slug":5365,"properties":5366,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"70334c5d-3a2b-43f1-9645-cd6f7f6d58d5","2025-02-06T04:24:40.305+00:00",[],"Division-of-Pediatric-Infectious-Diseases-Department-of-Pediatrics-Monroe-Carell-Jr-Children-s-Hospital-at-Vanderbilt-Vanderbilt-University-Medical-Center-Nashville-Tennessee",{"title":5367},{"EN":5368},"Division of Pediatric Infectious Diseases, Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, Tennessee",{"openalex":5370,"orcid":5372,"title":5374},{"VOID":5371},"A5026626377",{"VOID":5373},"https:\u002F\u002Forcid.org\u002F0000-0002-6381-1826",{"EN":5375},"Natasha Halasa",{"id":5377,"sortIndex":25,"researcher":24,"roles":5378,"affiliations":5379,"properties":5390},"e42061f0-7716-49fe-be80-4b241979250b",[],[5380],{"id":5381,"sortIndex":25,"affiliation":5382,"properties":24},"320b3518-f002-41f8-add5-e1f531fe1a0d",{"id":5383,"createTime":5384,"updateTime":5384,"relativeEntities":5385,"slug":5386,"properties":5387,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},"26ca4aa0-deb0-44fc-b65e-63d584bb00bc","2025-02-06T04:24:40.195+00:00",[],"Department-of-Pediatrics-Division-of-Infectious-Diseases-Cincinnati-Children-s-Hospital-Medical-Center-Ohio",{"title":5388},{"EN":5389},"Department of Pediatrics, Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Ohio",{"openalex":5391,"orcid":5393,"title":5395},{"VOID":5392},"A5077564846",{"VOID":5394},"https:\u002F\u002Forcid.org\u002F0000-0002-5691-5221",{"EN":5396},"Lara Danziger‐Isakov",{"id":5398,"sortIndex":354,"researcher":24,"roles":5399,"affiliations":5400,"properties":5407},"faed452f-dbf1-498f-9036-f68a76eb7d4a",[],[5401],{"id":5402,"sortIndex":25,"affiliation":5403,"properties":24},"19b600a9-e5e1-4d5d-b98c-e82cc670a3dd",{"id":5362,"createTime":5363,"updateTime":5363,"relativeEntities":5404,"slug":5365,"properties":5405,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":5406},{"EN":5368},{"openalex":5408,"orcid":5409,"title":5410},{"VOID":2952},{"VOID":2954},{"EN":2956},{"id":5412,"sortIndex":376,"researcher":24,"roles":5413,"affiliations":5414,"properties":5421},"2f53772b-42a7-44fb-b1ed-ad6a898aabe3",[],[5415],{"id":5416,"sortIndex":25,"affiliation":5417,"properties":24},"ae68eb93-6cb9-4625-9a70-13b0ba37fd4a",{"id":5243,"createTime":5244,"updateTime":5244,"relativeEntities":5418,"slug":5246,"properties":5419,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":5420},{"EN":5249},{"openalex":5422,"orcid":5424,"title":5426},{"VOID":5423},"A5100628988",{"VOID":5425},"https:\u002F\u002Forcid.org\u002F0000-0002-6011-2894",{"EN":5427},"Michael Green",{"id":5429,"sortIndex":209,"researcher":24,"roles":5430,"affiliations":5431,"properties":5438},"67216c34-aa8b-4087-826b-26aac30980d0",[],[5432],{"id":5433,"sortIndex":25,"affiliation":5434,"properties":24},"a81916cd-272b-4b30-ad09-79a554a42995",{"id":5383,"createTime":5384,"updateTime":5384,"relativeEntities":5435,"slug":5386,"properties":5436,"entityType":61,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25},[],{"title":5437},{"EN":5389},{"openalex":5439,"orcid":5441,"title":5443},{"VOID":5440},"A5023241218",{"VOID":5442},"https:\u002F\u002Forcid.org\u002F0000-0002-8901-6513",{"EN":5444},"Grant Paulsen",{"url":24,"publisher":5446,"properties":5471},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":5447,"slug":10,"properties":5448,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"syncStatus":23,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":5454,"manageAffiliations":5455,"indexDatabases":5456,"url":116,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":5449,"issn":5450,"introduce":5451,"eissn":5452,"title":5453},{"VOID":13},{"VOID":15},{"EN":17},{"VOID":19},{"EN":21},[],[],[5457,5464],{"id":76,"indexDatabase":5458,"url":91,"indexYears":24,"academicFieldIds":5463,"indexDatabaseRanking":24},{"id":78,"createTime":79,"updateTime":80,"relativeEntities":5459,"label":5460,"description":5461,"key":87,"publicationTags":5462,"standard":24},[],{"EN":83,"VI":83},{"VI":85,"EN":86},[89,90],[93,94],{"id":96,"indexDatabase":5465,"url":109,"indexYears":110,"academicFieldIds":5470,"indexDatabaseRanking":115},{"id":98,"createTime":99,"updateTime":100,"relativeEntities":5466,"label":5467,"description":5468,"key":106,"publicationTags":5469,"standard":24},[],{"EN":103,"VI":103},{"EN":103,"VI":105},[108],[112,113,114],{"volume":5472,"pages":5474,"issue":5476},{"VOID":5473},"8",{"VOID":5475},"197-204",{"VOID":431},{"total":3069,"publishYear":24,"statisticByYear":5478},{"2019":209,"2020":354,"2021":233,"2022":62,"2023":62,"2024":62},"2019-07-01",2019,[5482,5485,5489,5493,5497,5501,5505,5509,5513,5517,5521,5524,5528,5532,5536,5538,5542,5546],{"id":24,"text":5483,"url":24,"identifiers":5484},"US Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Bureau, 2013, Child health USA 2012",{},{"id":24,"text":5486,"url":24,"identifiers":5487},"Flagg, 2010, Novel 2009 H1N1 influenza virus infection requiring extracorporeal membrane oxygenation in a pediatric heart transplant recipient, J Heart Lung Transplant, 29, 582, 10.1016\u002Fj.healun.2009.11.600",{"doi":5488},"10.1016\u002Fj.healun.2009.11.600",{"id":24,"text":5490,"url":24,"identifiers":5491},"Evashuk, 2008, Respiratory failure associated with human metapneumovirus infection in an infant posthepatic transplant, Am J Transplant, 8, 1567, 10.1111\u002Fj.1600-6143.2008.02278.x",{"doi":5492},"10.1111\u002Fj.1600-6143.2008.02278.x",{"id":24,"text":5494,"url":24,"identifiers":5495},"Blanchard, 2006, Significant morbidity associated with RSV infection in immunosuppressed children following liver transplantation: case report and discussion regarding need of routine prophylaxis, Pediatr Transplant, 10, 826, 10.1111\u002Fj.1399-3046.2006.00583.x",{"doi":5496},"10.1111\u002Fj.1399-3046.2006.00583.x",{"id":24,"text":5498,"url":24,"identifiers":5499},"Gavaldà, 2012, Influenza A H1N1\u002F2009 infection in pediatric solid organ transplant recipients, Transpl Infect Dis, 14, 584, 10.1111\u002Ftid.12005",{"doi":5500},"10.1111\u002Ftid.12005",{"id":24,"text":5502,"url":24,"identifiers":5503},"Lo, 2013, The impact of RSV, adenovirus, influenza, and parainfluenza infection in pediatric patients receiving stem cell transplant, solid organ transplant, or cancer chemotherapy, Pediatr Transplant, 17, 133, 10.1111\u002Fpetr.12022",{"doi":5504},"10.1111\u002Fpetr.12022",{"id":24,"text":5506,"url":24,"identifiers":5507},"Tran, 2013, Lower respiratory tract viral infections in pediatric abdominal organ transplant recipients: a single hospital inpatient cohort study, Pediatr Transplant, 17, 461, 10.1111\u002Fpetr.12093",{"doi":5508},"10.1111\u002Fpetr.12093",{"id":24,"text":5510,"url":24,"identifiers":5511},"Robinson, 2015, Respiratory syncytial virus infections in pediatric transplant recipients: a Canadian Paediatric Surveillance Program study, Pediatr Transplant, 19, 659, 10.1111\u002Fpetr.12553",{"doi":5512},"10.1111\u002Fpetr.12553",{"id":24,"text":5514,"url":24,"identifiers":5515},"Kumar, 2010, Outcomes from pandemic influenza A H1N1 infection in recipients of solid-organ transplants: a multicentre cohort study, Lancet Infect Dis, 10, 521, 10.1016\u002FS1473-3099(10)70133-X",{"doi":5516},"10.1016\u002FS1473-3099(10)70133-X",{"id":24,"text":5518,"url":24,"identifiers":5519},"Liu, 2009, Respiratory viral infections within one year after pediatric lung transplant, Transpl Infect Dis, 11, 304, 10.1111\u002Fj.1399-3062.2009.00397.x",{"doi":5520},"10.1111\u002Fj.1399-3062.2009.00397.x",{"id":24,"text":5522,"url":24,"identifiers":5523},"Fisher, 2017, A multicenter consortium to define the epidemiology and outcomes of inpatient respiratory viral infections in pediatric hematopoietic stem cell transplant recipients, J Pediatric Infect Dis Soc",{},{"id":24,"text":5525,"url":24,"identifiers":5526},"Fisher, 2016, Symptomatic respiratory virus infection and chronic lung allograft dysfunction, Clin Infect Dis, 62, 313, 10.1093\u002Fcid\u002Fciv871",{"doi":5527},"10.1093\u002Fcid\u002Fciv871",{"id":24,"text":5529,"url":24,"identifiers":5530},"Sayah, 2013, Rhinovirus and other respiratory viruses exert different effects on lung allograft function that are not mediated through acute rejection, Clin Transplant, 27, E64, 10.1111\u002Fctr.12054",{"doi":5531},"10.1111\u002Fctr.12054",{"id":24,"text":5533,"url":24,"identifiers":5534},"Apalsch, 1995, Parainfluenza and influenza virus infections in pediatric organ transplant recipients, Clin Infect Dis, 20, 394, 10.1093\u002Fclinids\u002F20.2.394",{"doi":5535},"10.1093\u002Fclinids\u002F20.2.394",{"id":24,"text":5514,"url":24,"identifiers":5537},{"doi":5516},{"id":24,"text":5539,"url":24,"identifiers":5540},"Liu, 2010, Long-term impact of respiratory viral infection after pediatric lung transplantation, Pediatr Transplant, 14, 431, 10.1111\u002Fj.1399-3046.2010.01296.x",{"doi":5541},"10.1111\u002Fj.1399-3046.2010.01296.x",{"id":24,"text":5543,"url":24,"identifiers":5544},"Bridges, 1998, Adenovirus infection in the lung results in graft failure after lung transplantation, J Thorac Cardiovasc Surg, 116, 617, 10.1016\u002FS0022-5223(98)70168-0",{"doi":5545},"10.1016\u002FS0022-5223(98)70168-0",{"id":24,"text":5547,"url":24,"identifiers":5548},"Chu, 2016, Clinical outcomes in outpatient respiratory syncytial virus infection in immunocompromised children, Influenza Other Respir Viruses, 10, 205, 10.1111\u002Firv.12375",{"doi":5549},"10.1111\u002Firv.12375"]