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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":565,"VI":566},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":568},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[572],{"id":573,"createTime":24,"updateTime":24,"relativeEntities":574,"slug":24,"properties":575,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":585,"parentIds":586,"statistic":24},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":576,"address":579,"country":582,"abbreviation":583},{"EN":577,"VI":578},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":580,"VI":581},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":96},{"VOID":584},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":25,"impactFactorByYear":590,"i10Index":25,"i10IndexLast5Year":25,"totalPublication":592,"totalPublicationByYear":593,"totalCitation":598,"totalCitationByYear":599,"totalCitationPerPublication":186,"totalCitationPerPublicationByYear":601,"hindexLast5Year":123,"hindex":123},{"2022":591,"2023":189,"2024":184},0.01,1556,{"2020":125,"2021":594,"2022":595,"2023":596,"2024":597,"2025":200},57,306,801,358,161,{"2021":224,"2022":358,"2023":600},99,{"2021":602,"2022":396,"2023":182},0.23,{"impactFactor":24,"impactFactorByYear":24,"i10Index":201,"i10IndexLast5Year":201,"totalPublication":604,"totalPublicationByYear":605,"totalCitation":604,"totalCitationByYear":606,"totalCitationPerPublication":118,"totalCitationPerPublicationByYear":609,"hindexLast5Year":127,"hindex":127},476,{"0":283,"2019":201,"2021":217,"2022":537,"2023":529,"2024":435,"2025":127,"2026":126},{"2021":120,"2022":201,"2023":239,"2024":607,"2025":438,"2026":608},136,83,{"2021":183,"2022":591,"2023":610,"2024":205,"2025":611,"2026":612},0.62,25.43,13.83,{"id":614,"createTime":615,"updateTime":460,"relativeEntities":616,"slug":617,"properties":618,"entityType":22,"verifyStatus":106,"verifyTime":24,"verifyNote":24,"languages":630,"translateLanguages":24,"viewCount":211,"subjectFields":631,"manageAffiliations":632,"indexDatabases":633,"url":634,"thumbnailPath":635,"statistic":636,"gsStatistic":672,"type":133,"analyzePriority":24},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":619,"issn":620,"title":622,"introduce":625,"gsId":628},{"VOID":96},{"VOID":621},"25252445",{"EN":623,"VI":624},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":626,"VI":627},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. Since then, the journal has grown in quality, size and scope and now comprises a dozen of serials spanning academic research. 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Có giả thuyết rằng co thắt phế quản đóng vai trò rất ít hoặc không đóng vai trò nào trong sự bong tróc của niêm mạc phế quản hoặc trong sinh bệnh học của cơn hen phế quản.\u003C\u002Fjats:p>","\u003Cjats:p>The pathological features of 20 cases dying in status asthmaticus have been studied. In gross sections the lungs showed no emphysema, but mucus plugs in the air passages and focal areas of collapse were outstanding features. Five cases showed cystic bronchiectasis which was of a similar distribution to the focal areas of collapse, occurring in the upper lobes as commonly as in the lower lobes.\u003C\u002Fjats:p>\u003Cjats:p>Histologically, shedding of the ciliated bronchial mucosal cells was prominent and this is attributed to a transudation of oedema fluid from the submucosa. Areas of regeneration of the mucosa, with the presence of simple stratified epithelium, were seen frequently. The loss of the ciliated respiratory epithelium and the transudation of oedema fluid into the bronchial lumen, with interference with the action of the remaining ciliated cells, are considered to be the essential factors in the failure of clearance of the bronchial secretions in asthma. It is postulated that bronchospasm plays little or no part in the shedding of the bronchial mucosa or in the pathogenesis of the asthmatic attack.\u003C\u002Fjats:p>",{"EN":1414,"VI":1415},"THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA","BỆNH PHẨM HỌC CỦA BÊNH PHỔI KÍN, VỚI THAM CHIẾU ĐẶC BIỆT ĐẾN CÁC THAY ĐỔI TRONG NIÊM MẠC PHẾ QUẢN",{"VOID":1417},"13818688",{"VOID":1419},"10.1136\u002Fjcp.13.1.27",[110],[109],"https:\u002F\u002Fjcp.bmj.com\u002Flookup\u002Fdoi\u002F10.1136\u002Fjcp.13.1.27",[1424],{"id":1425,"sortIndex":25,"researcher":24,"roles":1426,"affiliations":1427,"properties":1436},"79387a49-8039-48cc-a0f6-cab1969a8028",[],[1428],{"id":1429,"sortIndex":25,"affiliation":1430,"properties":24},"2ba7aaa9-1b14-4657-9245-ddf14ab4e3bd",{"id":1429,"createTime":24,"updateTime":24,"relativeEntities":1431,"slug":24,"properties":1432,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1435,"statistic":24},[],{"title":1433},{"EN":1434},"Department of Pathology, the Radcliffe Infirmary, Oxford",[],{"title":1437,"openalex":1439},{"EN":1438},"M. S. Dunnill",{"VOID":1440},"A5080264064",{"url":24,"publisher":1442,"properties":1479},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1443,"slug":10,"properties":1444,"entityType":22,"verifyStatus":23,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":25,"subjectFields":1449,"manageAffiliations":1458,"indexDatabases":1464,"url":83,"thumbnailPath":24,"statistic":24,"gsStatistic":24,"type":24,"analyzePriority":24},[],{"country":1445,"eissn":1446,"issn":1447,"title":1448},{"VOID":13},{"VOID":15},{"VOID":17},{"EN":19},[1450,1454],{"id":28,"createTime":24,"updateTime":24,"relativeEntities":1451,"label":1452,"description":1453,"parentId":24,"standard":24,"scholarHubFieldId":24},[],{"EN":31},{},{"id":34,"createTime":24,"updateTime":24,"relativeEntities":1455,"label":1456,"description":1457,"parentId":24,"standard":24,"scholarHubFieldId":24},[],{"EN":37},{},[1459],{"id":41,"createTime":24,"updateTime":24,"relativeEntities":1460,"slug":24,"properties":1461,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1463,"statistic":24},[],{"title":1462},{"EN":45},[],[1465,1472],{"id":49,"indexDatabase":1466,"url":60,"indexYears":61,"academicFieldIds":1471,"indexDatabaseRanking":65},{"id":51,"createTime":24,"updateTime":24,"relativeEntities":1467,"label":1468,"description":1469,"key":57,"publicationTags":1470,"standard":24},[],{"EN":54,"VI":54},{"EN":54,"VI":56},[59],[63,64],{"id":67,"indexDatabase":1473,"url":80,"indexYears":24,"academicFieldIds":1478,"indexDatabaseRanking":24},{"id":69,"createTime":24,"updateTime":24,"relativeEntities":1474,"label":1475,"description":1476,"key":76,"publicationTags":1477,"standard":24},[],{"EN":72,"VI":72},{"EN":74,"VI":75},[78,79],[82],{"issue":1480,"pages":1482,"volume":1484},{"VOID":1481},"1",{"VOID":1483},"27-33",{"VOID":1485},"13",1008,{"total":1486,"publishYear":1488,"statisticByYear":1489},1960,{"2012":277,"2013":277,"2014":401,"2015":208,"2016":123,"2017":435,"2018":224,"2019":125,"2020":129,"2021":207,"2022":204,"2023":125,"2024":126},"1960-01-01",[78,65],[1493,1496,1499,1503,1506,1509,1513,1517,1521,1525,1529,1532,1535,1539,1542,1545,1549,1553],{"id":24,"text":1494,"url":24,"identifiers":1495},"Cohen, R. C., and Prentice, A. I. D. (1959). Tubercle (Lond.), 40,44.",{},{"id":24,"text":1497,"url":24,"identifiers":1498},"Curschmann, H. (1883). Dtsch. Arch. klin. Med., 32, 1.",{},{"id":24,"text":1500,"url":24,"identifiers":1501},"Dixon, F. J., and Warren, S. (1950). Amer. J. med. Sci., 219, 414.",{"doi":1502},"10.1097\u002F00000441-195004000-00007",{"id":24,"text":1504,"url":24,"identifiers":1505},"Ellis, A. G. (1908). Ibid., 136, 407.",{},{"id":24,"text":1507,"url":24,"identifiers":1508},"Florey, H. W. (1958). In General Pathology, ed. H. W. Florey, 2nd ed., p. 120. Lloyd-Luke, London.",{},{"id":24,"text":1510,"url":24,"identifiers":1511},"Gough, J. (1955). Lancet, 1, 161.",{"doi":1512},"10.1016\u002FS0140-6736(55)91902-4",{"id":24,"text":1514,"url":24,"identifiers":1515},"Hilding, A. (1932). Amer. J. Physiol., 100, 664.",{"doi":1516},"10.1152\u002Fajplegacy.1932.100.3.664",{"id":24,"text":1518,"url":24,"identifiers":1519},"Holden, W. S., and Ardran, G. M. (1957). J. Fac. Radiol. (Lond.), 8, 267. Houston, J.",{"doi":1520},"10.1016\u002FS0368-2242(57)80027-X",{"id":24,"text":1522,"url":24,"identifiers":1523},"R. (1953). Thorax, 8, 207.",{"doi":1524},"10.1136\u002Fthx.8.3.207",{"id":24,"text":1526,"url":24,"identifiers":1527},"Lander, F. P. L.. and Davidson, M. (1938). Brit. J. Radiol., 11, 65.",{"doi":1528},"10.1259\u002F0007-1285-11-122-65",{"id":24,"text":1530,"url":24,"identifiers":1531},"Liebow, A. A., Hales, M. R., and Lindskog, G. E. (1949). Amer. J. Path., 25, 211.",{},{"id":24,"text":1533,"url":24,"identifiers":1534},"Otto, H., and Wagner, H. (1956). Beitr. path. Anat., 116, 436.",{},{"id":24,"text":1536,"url":24,"identifiers":1537},"Reid, Lynne McA. (1954). Lancet, 1, 275.",{"doi":1538},"10.1016\u002FS0140-6736(54)91030-2",{"id":24,"text":1540,"url":24,"identifiers":1541},"Robb-Smith, A. Segal, M. S., and H. T. (1952).",{},{"id":24,"text":1543,"url":24,"identifiers":1544},"In Clinical Cardiopulmonary Physiology [American College of Chest Physiciansl, ed. B. L.",{},{"id":24,"text":1546,"url":24,"identifiers":1547},"Sheldon, M. B., and Otis, A. B. (1951). J. appl. Physiol., 3, 513.",{"doi":1548},"10.1152\u002Fjappl.1951.3.9.513",{"id":24,"text":1550,"url":24,"identifiers":1551},"Wilhelm, D. L. (1953). J. Path. Bact., 65, 543.",{"doi":1552},"10.1002\u002Fpath.1700650226",{"id":24,"text":1554,"url":24,"identifiers":1555},"Young, F. H. (1959). Chest and Heart Bull., 8, 4t.",{},{"id":1557,"createTime":1558,"updateTime":1558,"relativeEntities":1559,"slug":1560,"properties":1561,"entityType":959,"verifyStatus":106,"verifyTime":1558,"verifyNote":960,"languages":1574,"translateLanguages":24,"viewCount":25,"primaryUrl":1575,"fullTextUrl":24,"authors":1576,"publicationType":999,"publisherRelationship":1609,"citationCount":1653,"citationInfo":1654,"publishDate":1657,"publishYear":1655,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":1658,"openAccess":24,"references":1659,"isForceReanalyzing":1058},"95a09672-0acf-471a-9a4f-7ccd283f8c5c","2024-10-08T01:54:54.817+00:00",[],"A-Rapid-and-Simple-Method-for-the-Determination-of-Esterified-Fatty-Acids-and-for-Total-Fatty-Acids-in-Blood",{"openalex":1562,"mag":1564,"title":1566,"pm":1568,"doi":1570,"pmc":1572},{"VOID":1563},"W2040735261",{"VOID":1565},"2040735261",{"EN":1567},"A Rapid and Simple Method for the Determination of Esterified Fatty Acids and for Total Fatty Acids in Blood",{"VOID":1569},"13052741",{"VOID":1571},"10.1136\u002Fjcp.6.2.158",{"VOID":1573},"1023578",[110],"http:\u002F\u002Fjcp.bmj.com\u002Fcgi\u002Fdoi\u002F10.1136\u002Fjcp.6.2.158",[1577,1594],{"id":1578,"sortIndex":25,"researcher":24,"roles":1579,"affiliations":1580,"properties":1589},"7eb5b8f4-08c0-4e8f-94d2-1f106e7b9dea",[],[1581],{"id":1582,"sortIndex":25,"affiliation":1583,"properties":24},"761083c8-8ef3-4e57-ac76-b8032fcacdcc",{"id":1582,"createTime":24,"updateTime":24,"relativeEntities":1584,"slug":24,"properties":1585,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1588,"statistic":24},[],{"title":1586},{"EN":1587},"From the Laboratory for Pathological Physiology, the Hebrew University, Jerusalem, Israel",[],{"title":1590,"openalex":1592},{"EN":1591},"I. 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C., Jr., and Hirsch, E. F. (1949). Arch. Biochem., 20, 242.",{},{"id":24,"text":1664,"url":24,"identifiers":1665},"Feigi, F. (1949). Chemistry of Specific, Selective and Sensitive",{},{"id":24,"text":1667,"url":24,"identifiers":1668},"Hestnn, S. (1949). J. biol. Chem., 180, 249.",{"doi":1669},"10.1016\u002FS0021-9258(18)56740-5",{"id":24,"text":1671,"url":24,"identifiers":1672},"Lipmann, F., and Tuttle, L. C. (1945). Ibid., 159, 21.",{},{"id":24,"text":1674,"url":24,"identifiers":1675},"Lipmann, F., and Tuttle, L. C. (1950). Biochim. biophys. Acta, 4, 301.",{"doi":1676},"10.1016\u002F0006-3002(50)90036-9",{"id":1678,"createTime":1679,"updateTime":1680,"relativeEntities":1681,"slug":1682,"properties":1683,"entityType":959,"verifyStatus":106,"verifyTime":1679,"verifyNote":960,"languages":1700,"translateLanguages":1701,"viewCount":25,"primaryUrl":1702,"fullTextUrl":24,"authors":1703,"publicationType":999,"publisherRelationship":1795,"citationCount":1839,"citationInfo":1840,"publishDate":1845,"publishYear":1841,"citationAnalyzeStatus":23,"lastCitationAnalyze":24,"indexDatabases":1846,"openAccess":24,"references":1847,"isForceReanalyzing":1058},"21d1069b-cf4f-499e-bc74-b5779cbe6a6a","2024-10-17T09:00:54.433+00:00","2025-01-11T17:25:30.958+00:00",[],"Autopsy-in-suspected-COVID-19-cases",{"mag":1684,"keywords":1686,"openalex":1688,"abstract":1690,"title":1693,"pm":1696,"doi":1698},{"VOID":1685},"3010697991",{"VI":1687},"COVID-19, giải phẫu, SARS-CoV-2, bệnh lý, hướng dẫn",{"VOID":1689},"W3010697991",{"VI":1691,"EN":1692},"\u003Cjats:p>Sự bùng phát của hội chứng hô hấp cấp tính nghiêm trọng (SARS)-coronavirus-2 (CoV-2) ở Vũ Hán, Trung Quốc hiện đã lan ra nhiều quốc gia trên toàn thế giới, bao gồm cả Vương quốc Anh, với số lượng tử vong ngày càng tăng. Điều này chắc chắn sẽ dẫn đến sự gia tăng số lượng trường hợp nghi ngờ tử vong liên quan đến bệnh coronavirus 2019 (COVID-19) tại các cuộc giải phẫu tử thi. Viện Hàn lâm Y học Hoàng gia đã đáp ứng mối lo ngại này bằng cách công bố một hướng dẫn về thực hành giải phẫu liên quan đến COVID-19. Bài viết sau đây là tóm tắt và diễn giải những hướng dẫn này. Nó bao gồm mô tả về các sinh vật nhóm nguy cơ 3, danh mục mà SARS-CoV-2 đã được phân loại, một mô tả ngắn gọn về những gì hiện đang được biết đến về các phát hiện về bệnh lý và giải phẫu trong COVID-19, tóm tắt các khuyến nghị cho việc thực hiện giải phẫu trong các trường hợp nghi ngờ mắc COVID-19 và các kỹ thuật để đưa ra chẩn đoán tại giải phẫu. Bài viết kết thúc bằng việc xem xét mối tương quan lâm sàng-bệnh lý và thông báo các trường hợp như vậy.\u003C\u002Fjats:p>","\u003Cjats:p>The severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) outbreak in Wuhan, China has now spread to many countries across the world including the UK with an increasing death toll. This will inevitably lead to an increase in the number of suspected coronavirus disease 2019 (COVID-19)-related deaths at autopsy. The Royal College of Pathologists has responded to this concern with the release of a briefing on autopsy practice relating to COVID-19. The following article is a summary and interpretation of these guidelines. It includes a description of hazard group 3 organisms, the category to which SARS-CoV-2 has been assigned, a brief description of what is currently known about the pathological and autopsy findings in COVID-19, a summary of the recommendations for conducting autopsies in suspected COVID-19 cases and the techniques for making the diagnosis at autopsy. It concludes by considering the clinicopathological correlation and notification of such cases.\u003C\u002Fjats:p>",{"EN":1694,"VI":1695},"Autopsy in suspected COVID-19 cases","Giải phẫu bệnh trong các trường hợp nghi ngờ mắc COVID-19",{"VOID":1697},"32198191",{"VOID":1699},"10.1136\u002Fjclinpath-2020-206522",[110],[109],"https:\u002F\u002Fjcp.bmj.com\u002Flookup\u002Fdoi\u002F10.1136\u002Fjclinpath-2020-206522",[1704,1723,1742,1759,1776],{"id":1705,"sortIndex":25,"researcher":24,"roles":1706,"affiliations":1707,"properties":1716},"664b28af-3065-4057-82f4-124b18e78161",[],[1708],{"id":1709,"sortIndex":25,"affiliation":1710,"properties":24},"940661a2-88ad-4495-8c9f-a39e03b5a3af",{"id":1709,"createTime":24,"updateTime":24,"relativeEntities":1711,"slug":24,"properties":1712,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1715,"statistic":24},[],{"title":1713},{"EN":1714},"Cellular Pathology, Imperial College London NHS Trust, London, UK",[],{"orcid":1717,"title":1719,"openalex":1721},{"VOID":1718},"https:\u002F\u002Forcid.org\u002F0000-0003-4130-920X",{"EN":1720},"Brian Hanley",{"VOID":1722},"A5060745448",{"id":1724,"sortIndex":118,"researcher":24,"roles":1725,"affiliations":1726,"properties":1735},"8300d2d4-c81e-4859-be94-42551a4bd329",[],[1727],{"id":1728,"sortIndex":25,"affiliation":1729,"properties":24},"6ea3770d-cb49-48f7-8902-033745e96e91",{"id":1728,"createTime":24,"updateTime":24,"relativeEntities":1730,"slug":24,"properties":1731,"entityType":24,"verifyStatus":24,"verifyTime":24,"verifyNote":24,"languages":24,"translateLanguages":24,"viewCount":24,"url":24,"parentIds":1734,"statistic":24},[],{"title":1732},{"EN":1733},"Department of Histopathology, GKT, Medical school in London, London, UK",[],{"orcid":1736,"title":1738,"openalex":1740},{"VOID":1737},"https:\u002F\u002Forcid.org\u002F0000-0002-8718-0002",{"EN":1739},"Sebastian 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Available: https:\u002F\u002Fwww.gov.uk\u002Fgovernment\u002Fpublications\u002Fwuhan-novel-coronavirus-initial-investigation-of-possible-cases\u002Finvestigation-and-initial-clinical-management-of-possible-cases-of-wuhan-novel-coronavirus-wn-cov-infection",{},{"id":24,"text":1887,"url":24,"identifiers":1888},"10.1002\u002Fpath.1440",{"doi":1887},{"id":24,"text":1890,"url":24,"identifiers":1891},"10.1016\u002Fj.ajpath.2015.10.024",{"doi":1890},{"id":24,"text":1893,"url":24,"identifiers":1894},"Lucas S . Autopsies on people with high-risk infections. In: The hospital autopsy: a manual of fundamental autopsy practice. 3rd edition. London, UK: Hodder Arnold, 2010.",{"doi":1895},"10.1201\u002Fb13395-7",{"id":24,"text":1897,"url":24,"identifiers":1898},"NBS T . Hbn 20 facilities for mortuary and post-mortem room services (3rd edition). secondary HbN 20 facilities for mortuary and post-mortem room services (3rd edition), 2005. 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Available: https:\u002F\u002Fwww.gov.uk\u002Fgovernment\u002Fpublications\u002Fwuhan-novel-coronavirus-guidance-for-clinical-diagnostic-laboratories",{},{"id":24,"text":1910,"url":24,"identifiers":1911},"Henwood, 2020, Coronavirus disinfection in histopathology, J Histotechnol, 16, 1",{},{"id":1913,"createTime":1914,"updateTime":1915,"relativeEntities":1916,"slug":1917,"properties":1918,"entityType":959,"verifyStatus":106,"verifyTime":1914,"verifyNote":960,"languages":1939,"translateLanguages":1940,"viewCount":25,"primaryUrl":1941,"fullTextUrl":24,"authors":1942,"publicationType":999,"publisherRelationship":1960,"citationCount":779,"citationInfo":2004,"publishDate":2007,"publishYear":2005,"citationAnalyzeStatus":23,"lastCitationAnalyze":1915,"indexDatabases":2008,"openAccess":24,"references":2009,"isForceReanalyzing":1058},"acab8de1-6d79-47dc-8077-700835871f0b","2025-01-07T20:20:44.102+00:00","2026-03-29T15:09:29.279+00:00",[],"Methicillin-resistant-staphylococci",{"mag":1919,"gsPaper":1921,"keywords":1923,"pmc":1925,"openalex":1927,"abstract":1929,"title":1932,"pm":1935,"doi":1937},{"VOID":1920},"2123689798",{"VOID":1922},"[\"13170130993465289031\"]",{"VI":1924},"Staphylococcus, kháng methicillin, kháng thuốc, penicillin, nghiên cứu vi sinh",{"VOID":1926},"480239",{"VOID":1928},"W2123689798",{"VI":1930,"EN":1931},"\u003Cjats:p>Hai mươi bốn dòng vi khuẩn \u003Cjats:italic>Staph. pyogenes\u003C\u002Fjats:italic> (chín dòng nhạy cảm với penicillin và chín dòng có khả năng phá hủy penicillin) đã được nuôi cấy qua 40 đến 50 lần trên bề mặt đĩa Celbenin\u003Cjats:sup>1\u003C\u002Fjats:sup>.\u003C\u002Fjats:p>\u003Cjats:p>Tất cả các dòng vi khuẩn đều phát triển khả năng kháng lại Celbenin và tám dòng (bốn dòng nhạy cảm với penicillin và bốn dòng có khả năng phá hủy penicillin) có thể phát triển trong môi trường chứa 100 μg\u002Fml Celbenin hoặc cao hơn. Sự kháng thuốc này thuộc kiểu kháng thuốc có khả năng chịu đựng và không có văn hóa nào làm bất hoạt Celbenin. Có sự gia tăng liên quan trong khả năng chịu đựng với benzyl penicillin.\u003C\u002Fjats:p>\u003Cjats:p>Các dòng vi khuẩn có khả năng kháng Celbenin cao được tách ra từ các chủng staphylococci phá hủy penicillin hoàn toàn khác biệt với những dòng từ các chủng nhạy cảm với penicillin, cũng như với các staphylococci có khả năng chịu đựng penicillin G được tách ra \u003Cjats:italic>in vitro\u003C\u002Fjats:italic>, bởi vì chúng vẫn giữ được các đặc điểm văn hóa, hoạt tính đông tụ và hoạt tính hủy huyết, cùng với độ độc lực trên chuột của các dòng mẹ, và mức độ kháng thuốc vẫn ổn định sau nhiều lần nuôi cấy trong môi trường không có Celbenin.\u003C\u002Fjats:p>\u003Cjats:p>Ba dòng vi khuẩn kháng Celbenin xảy ra tự nhiên của \u003Cjats:italic>Staph. pyogenes\u003C\u002Fjats:italic> tách ra từ các quá trình nhiễm trùng cũng đã được nghiên cứu. Cả ba dòng đều phát triển mạnh mẽ trong nồng độ Celbenin lên đến 12,5 μg\u002Fml nhưng rất kém trong các nồng độ cao hơn.\u003C\u002Fjats:p>\u003Cjats:p>Ý nghĩa khả thi của những phát hiện này sẽ được thảo luận.\u003C\u002Fjats:p>","\u003Cjats:p>Eighteen strains of\u003Cjats:italic>Staph. pyogenes\u003C\u002Fjats:italic>(nine penicillin-sensitive and nine penicillin-destroying) were passaged 40 to 50 times on Celbenin\u003Cjats:sup>1\u003C\u002Fjats:sup>ditch plates.\u003C\u002Fjats:p>\u003Cjats:p>All strains developed an increase in resistance to Celbenin and eight strains (four penicillin-sensitive and four penicillin-destroying) were able to grow in 100 μg\u002Fml. or more Celbenin. Resistance was of the drug-tolerant type and none of the cultures inactivated Celbenin. There was an associated increase in tolerance to benzyl penicillin.\u003C\u002Fjats:p>\u003Cjats:p>The highly Celbenin-resistant cultures isolated from penicillin-destroying staphylococci were in sharp contrast to those from penicillin-sensitive strains, as well as to penicillin G-tolerant staphylococci isolated\u003Cjats:italic>in vitro\u003C\u002Fjats:italic>, because they retained the cultural characteristics, coagulase and haemolytic activity, and mouse virulence of the parent strains, and the degree of resistance remained stable after repeated passage in the absence of Celbenin.\u003C\u002Fjats:p>\u003Cjats:p>Three naturally occurring Celbenin-resistant strains of\u003Cjats:italic>Staph. pyogenes\u003C\u002Fjats:italic>isolated from infective processes were also studied. 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