[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"_public_publisher_byId_602af22d-543e-434a-8059-d1d48d57d322":3,"_public_publication_all{\"sortAscending\":false,\"sortField\":\"updateTime\",\"page\":0,\"size\":10,\"facet\":true,\"searchKey\":\"publisherId:602af22d-543e-434a-8059-d1d48d57d322,\"}":62},{"code":4,"data":5,"meta":21},"SUCCESS",{"id":6,"createTime":7,"updateTime":8,"relativeEntities":9,"slug":10,"properties":11,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":24,"manageAffiliations":25,"indexDatabases":26,"url":27,"thumbnailPath":21,"statistic":28,"gsStatistic":21,"type":21,"analyzePriority":21},"602af22d-543e-434a-8059-d1d48d57d322","2023-06-13T09:26:08.551+00:00","2025-12-04T06:49:00.828+00:00",[],"Journal-of-108-Clinical-Medicine-and-Pharmacy",{"country":12,"issn":14,"title":16},{"VOID":13},"VN",{"VOID":15},"18592872",{"EN":17,"VI":18},"Journal of 108 - Clinical Medicine and Pharmacy","TẠP CHÍ Y DƯỢC LÂM SÀNG 108","PUBLISHER","VERIFIED",null,"PENDING",36,[],[],[],"https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Fabout",{"impactFactor":29,"impactFactorByYear":30,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":36,"totalCitation":46,"totalCitationByYear":47,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":54,"hindexLast5Year":61,"hindex":61},0,{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},0.02,0.03,0.06,0.01,2103,{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},14,200,165,258,366,395,334,275,96,286,{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},24,63,69,29,2,0.14,{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},0.18,0.15,0.24,0.19,0.16,0.09,5,{"meta":63,"data":65},{"total":64},"2103",[66,297,373,462,582,676,851,948,1025,1139],{"id":67,"createTime":68,"updateTime":69,"relativeEntities":70,"slug":71,"properties":72,"entityType":85,"verifyStatus":20,"verifyTime":68,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":87,"primaryUrl":88,"fullTextUrl":89,"authors":90,"publicationType":273,"publisherRelationship":274,"citationCount":21,"citationInfo":21,"publishDate":293,"publishYear":294,"citationAnalyzeStatus":22,"lastCitationAnalyze":295,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"6034d0ba-05f3-4ffd-afc2-521d7e289eb9","2023-08-22T16:21:05.810+00:00","2025-07-16T23:58:23.049+00:00",[],"T%C3%ACm-hi%E1%BB%83u-%C4%91%E1%BA%B7c-%C4%91i%E1%BB%83m-v%C3%A0-m%E1%BB%99t-s%E1%BB%91-y%E1%BA%BFu-t%E1%BB%91-li%C3%AAn-quan-%C4%91%E1%BA%BFn-t%C3%ACnh-tr%E1%BA%A1ng-h%E1%BA%A1-%C4%91%C6%B0%E1%BB%9Dng-huy%E1%BA%BFt-%E1%BB%9F-b%E1%BB%87nh-nh%C3%A2n-%C4%91%C3%A1i-th%C3%A1o-%C4%91%C6%B0%E1%BB%9Dng-t%C3%ADp-2-%C4%91i%E1%BB%81u-tr%E1%BB%8B-t%E1%BA%A1i-B%E1%BB%87nh-vi%E1%BB%87n-Trung-%C6%B0%C6%A1ng-Qu%C3%A2n-%C4%91%E1%BB%99i-108",{"gsPaper":73,"keywords":75,"abstract":77,"title":80,"doi":83},{"VOID":74},"9246020774893869864",{"VI":76},"hạ đường huyết,Đái tháo đường",{"EN":78,"VI":79},"Objective: To research the characteristic and some factors relative to the type 2 diabetic patients with complications of hypoglycemia hospitalized at 108 Militairy Central Hospital. Subject and method: Descriptive and cross-sectional study 107 hypoglycemic patients hospitalized at 108 Military Central hospital from 4\u002F2020 to 5\u002F2021. Result: The mean age was 74.0 ± 10.6 years. Male\u002Ffemale: 1.3\u002F1. Mean blood glucose was 1.99 ± 0.69mmol\u002Fl. Mean hemoglobin A1C was 6.4% ± 1.2%. Diabetes duration ranged over 10 years. Symptomatic patients accounted for 100% and 83.2% patients had neurologic symptoms. The rate of eating disorders\u002Fskipping meals was 71%. During the study we found that 89% diabetes melitus patients had hypertension and 66.3% had chronic kidney disease. 50.3% patients had hypoglycemia in the past. Symptomatic patients accounted for 100% and 83.2% patients had neurologic symptoms. The proportion of patients with hypoglycemia due to taking drugs including Insulin was the highest at 53.2% and including sulfunylure was 50.4%. Conclusion: Elderly diabetic patients who were on long term treatment, had renal failure and using Insulin or Sulfonylurea had the risk of hypoglycemia.","Mục tiêu: Tìm hiểu đặc điểm và một số yếu tố liên quan đến tình trạng hạ đường huyết ở bệnh nhân đái tháo đường típ 2 điều trị tại Bệnh viện Trung ương Quân đội 108. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang 107 bệnh nhân hạ đường huyết điều trị tại Bệnh viện Trung ương Quân đội 108 từ tháng 4\u002F2020 đến tháng 5\u002F2021. Kết quả: Tuổi trung bình là 74,0 ± 10,6 năm, tỷ lệ nam\u002Fnữ: 1,3\u002F1. Giá trị đường huyết trung bình lúc nhập viện là 1,99 ± 0,69mmol\u002Fl. HbA1c trung bình là 6,4% ± 1,2%. Tỷ lệ mắc bệnh trên 10 năm là 38,4%. 100% bệnh nhân có triệu chứng lâm sàng và 83,2% có rối loạn ý thức. Tỷ lệ ăn kém\u002Fbỏ ăn bị hạ đường huyết chiếm 71%. 89% bệnh nhân có bệnh lý tăng huyết áp đi kèm, 66,3% có suy thận kèm theo. Tỷ lệ các trường hợp có tiền căn hạ đường huyết chiếm 50,3%. Tỷ lệ bệnh nhân hạ đường huyết có dùng thuốc insulin là cao nhất sau đó là đến sulfonylurea với tỷ lệ lần lượt là 53,2% và 50,4%. Kết luận: Bệnh nhân đái tháo đường típ 2 tuổi cao, thời gian mắc bệnh kéo dài, có suy thận và sử dụng thuốc hạ đường huyết là insulin hoặc nhóm sulfonylurea thì có nguy cơ bị hạ đường huyết cao.",{"EN":81,"VI":82},"The research of the characteristic and some factors relative to the type 2 diabetic patients hospitalized at 108 Military Central Hospital","Tìm hiểu đặc điểm và một số yếu tố liên quan đến tình trạng hạ đường huyết ở bệnh nhân đái tháo đường típ 2 điều trị tại Bệnh viện Trung ương Quân đội 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báo","2021-08-09",2021,"2025-07-16T23:58:23.048+00:00",false,{"id":298,"createTime":299,"updateTime":300,"relativeEntities":301,"slug":302,"properties":303,"entityType":85,"verifyStatus":20,"verifyTime":314,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":315,"primaryUrl":316,"fullTextUrl":317,"authors":318,"publicationType":273,"publisherRelationship":352,"citationCount":29,"citationInfo":369,"publishDate":372,"publishYear":370,"citationAnalyzeStatus":22,"lastCitationAnalyze":300,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"1ef63b58-c0bb-4290-bf20-ad71e2b0f23d","2023-08-22T13:26:16.132+00:00","2024-12-30T23:58:07.693+00:00",[],"%C4%90%C3%A1nh-gi%C3%A1-k%E1%BA%BFt-qu%E1%BA%A3-sinh-thi%E1%BA%BFt-h%E1%BA%A1ch-c%E1%BB%ADa-c%C3%B3-%C4%91%E1%BB%8Bnh-h%C6%B0%E1%BB%9Bng-%C4%91%E1%BB%93ng-v%E1%BB%8B-ph%C3%B3ng-x%E1%BA%A1-k%E1%BA%BFt-h%E1%BB%A3p-v%E1%BB%9Bi-ch%E1%BA%A5t-ch%E1%BB%89-th%E1%BB%8B-m%C3%A0u-trong-ph%E1%BA%ABu-thu%E1%BA%ADt-%C4%91i%E1%BB%81u-tr%E1%BB%8B-ung-th%C6%B0-v%C3%BA-t%E1%BA%A1i-B%E1%BB%87nh-vi%E1%BB%87n-Ung-b%C6%B0%E1%BB%9Bu-Ngh%E1%BB%87-An",{"gsPaper":304,"keywords":306,"abstract":308,"title":311},{"VOID":305},"6513516455085360449",{"VI":307},"Sinh thiết hạch cửa,nạo hạch nách",{"EN":309,"VI":310},"Summary\r\nObjective: To evaluate the application of tumor marking technique and sentinel node biopsy in breast cancer treatment at Nghe An Oncology Hospital. Subject and method: From January 2017 to October 2018, we prospectively conducted 37 cases early breast cancer were treated with sentinel node biopsy (SNB) followed by completion axillary lymph node dissection (ALD). All sentinel and nonsentinel nodes were examined intraoperatively with frozen section and imprint, postoperatively with H&E staining. Identification and false-negative rate were defined. The value of this procedure is based on sensitivity, specificity, negative predictive values (NPV) and the accuracy. Result: The mean age was 50.7. Most tumors (83.8%) located at the upper lateral quarter. The mean diameter of tumors was 2.3cm, 70.3% patients were at stage IIa. Invasive ductal carcinoma accounted for 89.2%, histological grade 2 accounted for 67.5%. Sentinel node detection rate was 97.3%, in which 87.5% were determined by the radioactive method combined with color indicator, 12.5%. The mean number of sentinel node detected was 2.11 ± 0.75. Sensitivity was 100%, specificity was 96%, positive predictive valure was 91.7%, negative predictive value was 100%, overall accuracy value was 97.2%, false negative rate was 3.8%. Tumor diameter, histological grade did not affect the sentinel node detection rate. Conclusion: SNB with the radioactive method combined with color indicator is a safe and reliable technique with high accuracy in axillary staging for early breast cancer patients. This procedure is useful in early breast cancer treatment, reducing unnecessary axillary lymph node dissection for patients.\r\nKeywords: Sentinel node biopsy (SNB), axillary lymph node dissection (ALD).","Tóm tắt \r\nMục tiêu: Đánh giá kết quả sinh thiết hạch cửa có định hướng đồng vị phóng xạ kết hợp với chất chỉ thị màu trong phẫu thuật điều trị ung thư vú tại Bệnh viện Ung bướu Nghệ An. Đối tượng và phương pháp: Từ tháng 1\u002F2017 đến tháng 1\u002F2018, chúng tôi tiền cứu 37 bệnh nhân carcinôm vú giai đoạn 0-I-II được sinh thiết hạch cửa và nạo hạch nách. Tất cả hạch cửa được đánh giá bằng cắt lạnh và nhuộm H&E sau mổ. Ghi nhận tỷ lệ nhận diện, âm tính giả, dương tính giả. Giá trị của thủ thuật này dựa vào độ nhạy, độ đặc hiệu, giá trị tiên đoán âm tính và độ chính xác. Kết quả: Tuổi trung bình của bệnh nhân là 50,7 tuổi. Vị trí khối u đa số ở 1\u002F4 trên ngoài (83,8%). Kích thước khối u trung bình 2,3cm, 70,3% số bệnh nhân ở giai đoạn IIa.  Ung thư biểu mô thể ống xâm lấn chiếm tỷ lệ 89,2%, mô học độ 2 chiếm 67,5%. Tỷ lệ phát hiện hạch cửa là 97,3% trong đó 87,5% được xác định bằng có định hướng đồng vị phóng xạ kết hợp chỉ thị màu, 12,5%. Số lượng hạch cửa xác định được trung bình là 2,11 ± 0,75. Độ nhạy là 100%, độ đặc hiệu là 96%, giá trị dự báo dương tính là 91,7%, giá trị dự báo âm tính là 100%, độ chính xác toàn bộ là 97,2%, tỷ lệ âm tính giả là 0%, tỷ lệ dương tính giả 3,8%. Các yếu tố kích thước u, độ mô học không thấy có ảnh hưởng đến tỷ lệ phát hiện hạch cửa. Kết luận: Sinh thiết hạch cửa có định hướng đồng vị phóng xạ kết hợp chất chỉ thị màu là phương pháp an toàn, có độ chính xác cao. Thủ thuật này thực sự hữu ích trong điều trị ung thư vú giai đoạn sớm giúp bệnh nhân tránh được việc nạo vét hạch nách không cần thiết.\r\nTừ khóa: Sinh thiết hạch cửa, nạo hạch nách.\r\n",{"EN":312,"VI":313},"Application of tumor marking technique and sentinel node biopsy in breast cancer treatment at Nghe An Oncology Hospital","Đánh giá kết quả sinh thiết hạch cửa có định hướng đồng vị phóng xạ kết hợp với chất chỉ thị màu trong phẫu thuật điều trị ung thư vú tại Bệnh viện Ung bướu Nghệ An","2023-08-22T13:26:16.131+00:00",11,"https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F558","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F558\u002F331",[319,338],{"id":320,"sortIndex":29,"researcher":21,"roles":321,"affiliations":322,"properties":335},"7600138b-bcb2-46b9-b335-4338933d2d89",[],[323],{"id":21,"sortIndex":29,"affiliation":324,"properties":21},{"id":325,"createTime":326,"updateTime":327,"relativeEntities":328,"slug":329,"properties":330,"entityType":112,"verifyStatus":20,"verifyTime":333,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":334},"c3ea3dfc-c9f6-41e0-b9b5-510d4ac4367d","2023-05-17T06:58:08.480+00:00","2025-01-26T13:49:48.207+00:00",[],"B%E1%BB%87nh%20vi%E1%BB%87n%20Ung%20b%C6%B0%E1%BB%9Bu%20Ngh%E1%BB%87%20An",{"title":331},{"VI":332},"Bệnh viện Ung bướu Nghệ An","2023-09-28T07:15:20.860+00:00",18,{"title":336},{"VI":337},"Vũ  Đình Giáp",{"id":339,"sortIndex":29,"researcher":21,"roles":340,"affiliations":341,"properties":347},"ac909aba-1893-4dd9-bbd3-52592d220213",[],[342],{"id":21,"sortIndex":29,"affiliation":343,"properties":21},{"id":325,"createTime":326,"updateTime":327,"relativeEntities":344,"slug":329,"properties":345,"entityType":112,"verifyStatus":20,"verifyTime":333,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":334},[],{"title":346},{"VI":332},{"gsAuthor":348,"title":350},{"VOID":349},"KqxOJqAAAAAJ",{"VI":351},"Nguyễn   Quang Trung",{"url":316,"publisher":353,"properties":367},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":354,"slug":10,"properties":355,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":359,"manageAffiliations":360,"indexDatabases":361,"url":27,"thumbnailPath":21,"statistic":362,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":356,"issn":357,"title":358},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":363,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":364,"totalCitation":46,"totalCitationByYear":365,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":366,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":368},{"EN":291,"VI":292},{"total":29,"publishYear":370,"statisticByYear":371},2019,{},"2019-03-03",{"id":374,"createTime":375,"updateTime":376,"relativeEntities":377,"slug":378,"properties":379,"entityType":85,"verifyStatus":20,"verifyTime":376,"verifyNote":387,"syncStatus":22,"languages":388,"translateLanguages":21,"viewCount":29,"primaryUrl":390,"fullTextUrl":391,"authors":392,"publicationType":273,"publisherRelationship":444,"citationCount":21,"citationInfo":21,"publishDate":459,"publishYear":460,"citationAnalyzeStatus":22,"lastCitationAnalyze":21,"indexDatabases":21,"openAccess":21,"references":461,"isForceReanalyzing":296},"d88de48b-26e6-45df-9fd0-5d223e1e5b7b","2024-04-15T17:09:32.454+00:00","2025-01-21T23:55:12.883+00:00",[],"Relationships-between-some-apolipoproteins-and-atherosclerosis-condition-of-cerebral-infarction-patients",{"keywords":380,"abstract":382,"title":385},{"VI":381},"Nhồi máu não,apoA-I,apoB,vữa xơ động mạch",{"VI":383,"EN":384},"Tóm tắt \r\nMục tiêu: Nghiên cứu mối liên quan giữa nồng độ apolipoprotein A-I huyết tương, apolipoprotein B huyết tương, tỷ số apolipoprotein B\u002Fapolipoprotein A-I với tình trạng hẹp, tắc động mạch não của bệnh nhân nhồi máu não do vữa xơ động mạch. Đối tượng và phương pháp: 146 bệnh nhân nhồi máu não do vữa xơ động mạch được khám, điều trị tại Bệnh viện Trung ương Quân đội 108 từ tháng 10\u002F2017 đến tháng 12\u002F2019. Các bệnh nhân được khám lâm sàng, chẩn đoán hình ảnh và xét nghiệm apoA-I, apoB, tỷ số apoB\u002FapoA-I khi vào viện. Kết quả: Nồng độ apoA-I huyết tương của bệnh nhân hẹp, tắc 1 vị trí (1,32 ± 0,23g\u002Fl) cao hơn của bệnh nhân hẹp, tắc nhiều vị trí (1,22 ± 0,22g\u002Fl) với p<0,01. Nồng độ apoB huyết tương, tỷ số apoB\u002FapoA-I của bệnh nhân hẹp, tắc 1 vị trí (1,26 ± 0,29g\u002Fl, 0,99 ± 0,32) thấp hơn của bệnh nhân hẹp, tắc nhiều vị trí (1,37 ± 0,30g\u002Fl, 1,17 ± 0,34) với p<0,05 và p<0,01. Nồng độ apoA-I huyết tương của nhóm nhồi máu não do vữa xơ động mạch tương quan nghịch với mức độ hẹp, tắc động mạch (r = -0,297, p=0,001). Nồng độ apoB huyết tương, tỷ số apoB\u002FapoA-I của nhóm nhồi máu não do vữa xơ động mạch tương quan nghịch (r = 0,290, p=0,001 và r = 0,343, p=0,001) với mức độ hẹp, tắc động mạch. Kết luận: Có mối liên quan giữa nồng độ apoA-I, nồng độ apoB và tỷ số apoB\u002FapoA-I với tình trạng hẹp, tắc động mạch não của bệnh nhân nhồi máu não do vữa xơ động mạch.\r\nTừ khóa: Nhồi máu não, apoA-I, apoB, vữa xơ động mạch.\r\n ","Summary\r\nObjective: To study the relationships between concentrations of apolipoprotein A-I, apolipoprotein B, apolipoprotein B\u002Fapolipoprotein A-I ratio and cerebral artery stenosis, occlusion of patients with atherosclerotic cerebral infarction. Subject and method: 146 patients with atherosclerotic cerebral infarction were examined and treated at 108 Military Central Hospital from 10\u002F2017 - 12\u002F2019. Patients were examined clinically, diagnosed with imaging and tested apoA-I, apoB, apoB\u002FapoA-I ratio on admission. Result: The apoA-I concentration of patients with one site stenosis, occlusion (1.32 ± 0.23g\u002Fl) were higher than that of patients with multiple sites stenosis, occlusion (1.22 ± 0.22g\u002Fl) with p<0.01. The apoB concentration, the apoB\u002FapoA-I ratio of patients with one site stenosis, occlusion (1.26 ± 0.29g\u002Fl, 0.99 ± 0.32) were lower than that of patients with multiple sites stenosis, occlusion (1.37 ± 0.30g\u002Fl, 1.17 ± 0.34) with p<0.05 and p<0.01. The apoA-I concentration was inversely correlated with the degree of stenosis and occlusion (r = -0.297, p=0.001). The apoB concentration, the apoB\u002FapoA-I ratio were inversely correlated (r = 0.290, p=0.001 and r = 0.343, p=0.001) with the degree of cerebral artery stenosis, occlusion. Conclusion: There was a relationship between apoA-I concentration, apoB concentration, apoB\u002FapoA-I ratio and cerebral artery stenosis, occlusion of patients with atherosclerotic cerebral infarction.\r\nKeywords: Cerebral infarction, apoA-I, apoB, atherosclerosis.",{"EN":386},"Relationships between some apolipoproteins and atherosclerosis condition of cerebral infarction patients","Auto Verify",[389],"EN","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F489","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F489\u002F507",[393,410,427],{"id":394,"sortIndex":29,"researcher":21,"roles":395,"affiliations":396,"properties":407},"f6ae85be-dc81-4d13-9313-4a636bdb81fd",[],[397],{"id":398,"sortIndex":29,"affiliation":399,"properties":405},"883937a8-ba61-480a-bbf2-a97b14b143d9",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":400,"slug":102,"properties":401,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":402,"address":403,"abbreviation":404},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":406},{"VI":106},{"title":408},{"EN":409},"Nguyễn  Cẩm Thạch",{"id":411,"sortIndex":87,"researcher":21,"roles":412,"affiliations":413,"properties":424},"d1389eca-dfbc-4e4a-9152-7fbcc84c2cad",[],[414],{"id":415,"sortIndex":29,"affiliation":416,"properties":422},"2b7cabba-0c17-4baf-b19c-b81652b8ba45",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":417,"slug":102,"properties":418,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":419,"address":420,"abbreviation":421},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":423},{"VI":106},{"title":425},{"EN":426},"Nguyễn  Hoàng Ngọc",{"id":428,"sortIndex":52,"researcher":21,"roles":429,"affiliations":430,"properties":441},"85df157c-fcd5-4ba5-9d66-48eec2c3dad5",[],[431],{"id":432,"sortIndex":29,"affiliation":433,"properties":439},"7f112792-b33a-4e7a-a534-9a81768a73f8",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":434,"slug":102,"properties":435,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":436,"address":437,"abbreviation":438},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":440},{"VI":106},{"title":442},{"EN":443},"Nguyễn  Văn Tuyến",{"url":21,"publisher":445,"properties":21},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":446,"slug":10,"properties":447,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":451,"manageAffiliations":452,"indexDatabases":453,"url":27,"thumbnailPath":21,"statistic":454,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":448,"issn":449,"title":450},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":455,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":456,"totalCitation":46,"totalCitationByYear":457,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":458,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},"2020-07-07",2020,[],{"id":463,"createTime":464,"updateTime":465,"relativeEntities":466,"slug":467,"properties":468,"entityType":85,"verifyStatus":20,"verifyTime":464,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":29,"primaryUrl":481,"fullTextUrl":482,"authors":483,"publicationType":273,"publisherRelationship":563,"citationCount":21,"citationInfo":21,"publishDate":580,"publishYear":581,"citationAnalyzeStatus":22,"lastCitationAnalyze":465,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"e0affc6e-876b-474a-8ef5-b7b279dd4ce9","2023-08-22T12:27:52.188+00:00","2026-05-04T23:54:38.664+00:00",[],"%C4%90%C3%A1nh-gi%C3%A1-t%E1%BB%B7-l%E1%BB%87-t%E1%BB%93n-t%E1%BA%A1i-l%E1%BB%97-b%E1%BA%A7u-d%E1%BB%A5c-tr%C3%AAn-si%C3%AAu-%C3%A2m-tim-qua-th%E1%BB%B1c-qu%E1%BA%A3n-%E1%BB%9F-b%E1%BB%87nh-nh%C3%A2n-nh%E1%BB%93i-m%C3%A1u-n%C3%A3o-c%E1%BA%A5p",{"gsPaper":469,"keywords":471,"abstract":473,"title":476,"doi":479},{"VOID":470},"3788512093426656898",{"VI":472},"Siêu âm tim qua thực quản,tồn tại lỗ bầu dục,nhồi máu não",{"EN":474,"VI":475},"Objective: To determine the rate of patent foramen ovale on transesophageal echocardiography in patients with acute ischemic stroke. Subject and method: The study was implemented according to the cross-sectional study on patients with acute ischemic stroke who were implemented transesophageal echocardiography at Thong Nhat Hospital from June 2019 to February 2022. Result: A total of 400 patients with acute ischemic stroke met the inclusion criteria and were included in the study. The average age of the study population was 65.9 ± 12.1 years old, of which there were 286 patients (71.5%) ≥ 60 years old and 247 men patients (61.8%). The rate of the patent foramen ovale in the study was 27 patients (6.7%). There were no differences in age, sex, medical history, transthoracic and esophageal echocardiography, and brain magnetic resonance imaging between the two groups with and without patent foramen ovale. Conclusion: We found 6.7% of patients with acute ischemic stroke having patent foramen ovale detected on transesophageal echocardiography.","Mục tiêu: Xác định tỷ lệ tồn tại lỗ bầu dục trên siêu âm tim qua thực quản ở các bệnh nhân nhồi máu não cấp. Đối tượng và phương pháp: Nghiên cứu được thực hiện theo phương pháp cắt ngang trên các bệnh nhân nhồi máu não cấp được thực hiện siêu âm tim qua thực quản tại Bệnh viện Thống Nhất từ 6\u002F2019 đến 02\u002F2022. Kết quả: Có tổng cộng 400 bệnh nhân nhồi máu não cấp thỏa các tiêu chuẩn chọn bệnh và được đưa vào nghiên cứu. Độ tuổi trung bình của dân số nghiên cứu là 65,9 ± 12,1 tuổi, trong đó có 286 bệnh nhân (71,5%) ≥ 60 tuổi và có 247 bệnh nhân (61,8%) nam giới. Tỷ lệ tồn tại lỗ bầu dục trong nghiên cứu là 27 bệnh nhân (6,7%). Không có sự khác biệt về các đặc điểm tuổi, giới tính, bệnh lý nội khoa, đặc điểm siêu âm tim qua thành ngực và thực quản, đặc điểm tổn thương trên cộng hưởng từ sọ não giữa hai nhóm tồn tại lỗ bầu dục và không tồn tại lỗ bầu dục. Kết luận: Chúng tôi ghi nhận có 6,7% bệnh nhân nhồi máu não cấp tồn tại lỗ bầu dục được phát hiện trên siêu âm tim qua thực quản.",{"EN":477,"VI":478},"Evaluating the rate of patent foramen ovale on transesophageal echocardiography in patients with acute ischemic stroke","Đánh giá tỷ lệ tồn tại lỗ bầu dục trên siêu âm tim qua thực quản ở bệnh nhân nhồi máu não cấp",{"VOID":480},"10.52389\u002Fydls.v18i4.1853","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F1853","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F1853\u002F1541",[484,504,535],{"id":485,"sortIndex":29,"researcher":21,"roles":486,"affiliations":487,"properties":501},"50a0a1e0-2293-4c37-a345-b336f933db2d",[],[488],{"id":21,"sortIndex":29,"affiliation":489,"properties":21},{"id":490,"createTime":491,"updateTime":492,"relativeEntities":493,"slug":494,"properties":495,"entityType":112,"verifyStatus":20,"verifyTime":500,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":315},"802d2e15-068f-4435-8b28-e8ba9d931cd9","2023-06-13T16:03:35.127+00:00","2026-06-19T02:29:09.169+00:00",[],"Nguyen-Tat-Thanh-University",{"country":496,"title":497},{"VOID":13},{"EN":498,"VI":499},"Nguyen Tat Thanh University","Trường Đại học Nguyễn Tất Thành","2023-08-08T15:06:16.809+00:00",{"title":502},{"VI":503},"Nguyễn Quang  Huy",{"id":505,"sortIndex":29,"researcher":21,"roles":506,"affiliations":507,"properties":532},"7cdfb73c-601a-4ca4-ac79-a4db8c338feb",[],[508],{"id":509,"sortIndex":29,"affiliation":510,"properties":529},"018b87f7-06de-43d1-a9a5-4d06976c9969",{"id":511,"createTime":512,"updateTime":513,"relativeEntities":514,"slug":515,"properties":516,"entityType":112,"verifyStatus":20,"verifyTime":524,"verifyNote":525,"syncStatus":22,"languages":526,"translateLanguages":21,"viewCount":528},"7d3d2cd4-e09c-41e5-86fa-8d42de1e27b1","2023-05-09T04:35:56.332+00:00","2026-06-19T01:26:26.755+00:00",[],"B%E1%BB%87nh%20vi%E1%BB%87n%20Th%E1%BB%91ng%20Nh%E1%BA%A5t%20TP.%20H%E1%BB%93%20Ch%C3%AD%20Minh",{"country":517,"title":518,"address":521},{"VOID":13},{"EN":519,"VI":520},"Thong Nhat Hospital","Bệnh viện Thống Nhất",{"VI":522,"EN":523},"Số 1 đường Lý Thường Kiệt, Phường 7, quận Tân Bình, Thành phố Hồ Chí Minh, Việt Nam","No. 01 Ly Thuong Kiet Street, Tan Binh Dist, Ho Chi Minh City, Vietnam","2023-08-15T14:28:51.245+00:00","Verify when merge!",[527,389],"VI",23,{"title":530},{"VI":531},"Bệnh viện Thống Nhất, TP. Hồ Chí Minh",{"title":533},{"VI":534},"Nguyễn Văn Bé  Hai",{"id":536,"sortIndex":29,"researcher":21,"roles":537,"affiliations":538,"properties":560},"ad4e8b6c-69b2-4930-a75e-91e43dacfada",[],[539],{"id":540,"sortIndex":29,"affiliation":541,"properties":557},"3d615193-26cb-4046-9afb-75196a8b8317",{"id":542,"createTime":543,"updateTime":544,"relativeEntities":545,"slug":546,"properties":547,"entityType":112,"verifyStatus":20,"verifyTime":554,"verifyNote":525,"syncStatus":22,"languages":555,"translateLanguages":21,"viewCount":556},"a25af070-0db1-4848-8e1f-101acc4a1766","2023-05-09T04:37:48.554+00:00","2026-06-19T02:29:55.577+00:00",[],"Tr%C6%B0%E1%BB%9Dng%20%C4%90%E1%BA%A1i%20h%E1%BB%8Dc%20Y%20D%C6%B0%E1%BB%A3c%20TP.%20H%E1%BB%93%20Ch%C3%AD%20Minh",{"country":548,"title":549,"address":552},{"VOID":13},{"EN":550,"VI":551},"University of Medicine and Pharmacy at HCMC","Trường Đại học Y Dược Thành phố Hồ Chí Minh",{"VI":553},"Số 217 Hồng Bàng, Phường 11, Quận 5, Thành phố Hồ Chí Minh, Việt Nam","2023-08-13T09:18:30.020+00:00",[527,389],20,{"title":558},{"VI":559},"Đại học Y dược TP. Hồ Chí Minh",{"title":561},{"VI":562},"Nguyễn Thanh  Huân",{"url":481,"publisher":564,"properties":578},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":565,"slug":10,"properties":566,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":570,"manageAffiliations":571,"indexDatabases":572,"url":27,"thumbnailPath":21,"statistic":573,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":567,"issn":568,"title":569},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":574,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":575,"totalCitation":46,"totalCitationByYear":576,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":577,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":579},{"EN":291,"VI":292},"2023-02-23",2023,{"id":583,"createTime":584,"updateTime":585,"relativeEntities":586,"slug":587,"properties":588,"entityType":85,"verifyStatus":20,"verifyTime":601,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":602,"primaryUrl":603,"fullTextUrl":604,"authors":605,"publicationType":273,"publisherRelationship":657,"citationCount":21,"citationInfo":21,"publishDate":674,"publishYear":675,"citationAnalyzeStatus":22,"lastCitationAnalyze":585,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"c8ee7c89-4c6b-479e-b2da-1310437318ea","2023-08-22T08:21:31.416+00:00","2024-12-23T23:52:04.245+00:00",[],"Bi%E1%BB%83u-hi%E1%BB%87n-thanh-qu%E1%BA%A3n-c%E1%BB%A7a-b%E1%BB%87nh-gout-B%C3%A1o-c%C3%A1o-tr%C6%B0%E1%BB%9Dng-h%E1%BB%A3p-l%C3%A2m-s%C3%A0ng",{"gsPaper":589,"keywords":591,"abstract":593,"title":596,"doi":599},{"VOID":590},"2425090935049627355",{"VI":592},"Bệnh gout,thanh quản,gout thanh quản,hạt tophi thanh quản",{"EN":594,"VI":595},"Gout is a purine metabolic disorder that increases uric acid in the body and monosodium urate crystal deposition in tissues, a rare disease in the head and neck region, especially in the larynx. We report a case: A 37-year-old male patient, with a history of gout over 10 years, presented with hoarseness 3 months before admission, the initial lesion suspected of vocal cord cancer. Direct endoscopic biopsy results: Urate crystal deposition due to gout in the vocal cords. In the world, there are very few reports of gout manifesting in the larynx, in these report tophi of soft tissues in the larynx are extremely rare. This article, we discuss the pathophysiology, diagnosis and treatment for this case.","Gout là một bệnh rối loạn chuyển hóa các nhân purin làm tăng lượng acid uric trong cơ thể, gây lắng đọng tinh thể monosodium urat ở các mô, bệnh hiếm gặp ở vùng đầu cổ đặc biệt là thanh quản. Chúng tôi báo cáo trường hợp bệnh: Bệnh nhân nam 37 tuổi có tiền sử bệnh gout hơn 10 năm, biểu hiện khàn tiếng 3 tháng trước khi vào viện, ban đầu phát hiện tổn thương nghi ngờ ung thư dây thanh. Sinh thiết qua nội soi thanh quản trực tiếp cho kết quả: Lắng đọng tinh thể urat do gout ở dây thanh. Trên thế giới, có rất ít báo cáo về bệnh gout biểu hiện ở thanh quản, trong các báo cáo này hạt tophi của các mô mềm trong thanh quản là rất hiếm. Trong bài này, chúng tôi phân tích về sinh lý bệnh, chẩn đoán và điều trị ca bệnh hiếm gặp này.",{"EN":597,"VI":598},"Laryngeal manifestations of gout: A case report","Biểu hiện thanh quản của bệnh gout: Báo cáo trường hợp lâm sàng",{"VOID":600},"10.52389\u002Fydls.v17iDB.1446","2023-08-22T08:21:31.415+00:00",4,"https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F1446","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F1446\u002F1282",[606,623,640],{"id":607,"sortIndex":29,"researcher":21,"roles":608,"affiliations":609,"properties":620},"ca8b52f0-bb77-4e0f-8940-b74a819f8984",[],[610],{"id":611,"sortIndex":29,"affiliation":612,"properties":618},"86f0e75b-1b96-4738-b14e-888cbc624a15",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":613,"slug":102,"properties":614,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":615,"address":616,"abbreviation":617},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":619},{"EN":105,"VI":106},{"title":621},{"VI":622},"Vũ  Thị Ly",{"id":624,"sortIndex":29,"researcher":21,"roles":625,"affiliations":626,"properties":637},"9a3ee51b-c081-4e0f-9baf-bfd3d66dcee8",[],[627],{"id":628,"sortIndex":29,"affiliation":629,"properties":635},"801b4f9f-47e8-47d0-beaf-704173a20f82",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":630,"slug":102,"properties":631,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":632,"address":633,"abbreviation":634},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":636},{"EN":105,"VI":106},{"title":638},{"VI":639},"Nguyễn  Minh Ngọc",{"id":641,"sortIndex":29,"researcher":21,"roles":642,"affiliations":643,"properties":654},"de30e452-6764-4c36-a64c-89ca7c14408d",[],[644],{"id":645,"sortIndex":29,"affiliation":646,"properties":652},"123047e0-20c2-4d89-a8f2-225e0185e067",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":647,"slug":102,"properties":648,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":649,"address":650,"abbreviation":651},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":653},{"EN":105,"VI":106},{"title":655},{"VI":656},"Nguyễn  Văn Trường",{"url":603,"publisher":658,"properties":672},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":659,"slug":10,"properties":660,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":664,"manageAffiliations":665,"indexDatabases":666,"url":27,"thumbnailPath":21,"statistic":667,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":661,"issn":662,"title":663},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":668,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":669,"totalCitation":46,"totalCitationByYear":670,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":671,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":673},{"EN":291,"VI":292},"2022-11-12",2022,{"id":677,"createTime":678,"updateTime":679,"relativeEntities":680,"slug":681,"properties":682,"entityType":85,"verifyStatus":20,"verifyTime":691,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":52,"primaryUrl":692,"fullTextUrl":693,"authors":694,"publicationType":273,"publisherRelationship":831,"citationCount":29,"citationInfo":848,"publishDate":372,"publishYear":370,"citationAnalyzeStatus":22,"lastCitationAnalyze":850,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"4af4bdf1-00aa-4a93-89fb-9705df729241","2023-08-22T15:31:59.541+00:00","2025-11-25T23:50:05.779+00:00",[],"The-effects-of-combination-therapy-with-dutasteride-and-doxazosin-clinical-outcomes-in-men-with-symptomatic-benign-prostatic-hyperplasia",{"gsPaper":683,"keywords":685,"abstract":687,"title":689},{"VOID":684},"6061399270813719592",{"VI":686},"Dutasteride,doxazosin,benign prostatic hyperplasia",{"VI":688},"Objective: To investigate whether a combination of 0.5mg avodart plus 4mg doxazosin is more effective than 4mg doxazosin alone in treatment‐naïve men with moderately to severe symptomatic benign prostatic hyperplasia (BPH) at risk of progression. Subject and method: This was a multi-centre, randomised, open‐label, parallel‐group study in 100 men with an international prostate symptom score (IPSS) ≥ 8, prostate volume ≥ 30mL and total serum PSA level of < 4ng\u002FmL. Patients were randomised to 0.5mg avodart plus 4mg doxazosin (50 patients) or 4mg doxazosin alone (50) and followed for 6 months. The primary endpoint was symptomatic improvement from baseline to 6 months, measured by the IPSS. Secondary outcomes included BPH clinical progression, impact on quality of life (QoL), and safety. Result: The change in IPSS at 6 months was significantly greater for avodart plus doxazosin than doxazosin alone (-4.68 vs -0.02 points, p<0.05). With avodart plus doxazosin the risk of BPH progression was reduced by 36% (p<0.05), 18% and 12% of men in the doxazosin alone and avodart plus doxazosin groups had clinical progression, respectively, comprising symptomatic progression in most patients. Improvements in QoL (Question 8 of the IPSS) were seen in both groups but were significantly greater with avodart plus doxazosin groups compared with doxazosin alone, -1.46 vs 0.14, respectively (p<0.05). The occurrence of drug‐related AEs, was greater in the combined therapy group. The most commonly reported AEs across both groups were erectile dysfunction and retrograde ejaculation, which occurred in 6% vs 0% and 6% vs 4% patients in the combined therapy and doxazosin alone groups, respectively. Conclusion: The combined therapy with avodart plus doxazosin resulted in rapid and sustained improvements in men with moderate to severe BPH symptoms at risk of progression with significantly greater symptom and QoL improvements and a significantly reduced risk of BPH progression compared with doxazosin alone.",{"VI":690},"The effects of combination therapy with dutasteride and doxazosin clinical outcomes in men with symptomatic benign prostatic hyperplasia","2023-08-22T15:31:59.540+00:00","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F1129","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F1129\u002F750",[695,712,729,746,763,780,797,814],{"id":696,"sortIndex":29,"researcher":21,"roles":697,"affiliations":698,"properties":709},"f8dffb1f-7c0a-4e27-8b3b-ab66118f6691",[],[699],{"id":700,"sortIndex":29,"affiliation":701,"properties":707},"b2621751-b3ef-4574-8a83-51e389202800",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":702,"slug":102,"properties":703,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":704,"address":705,"abbreviation":706},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":708},{"EN":105,"VI":106},{"title":710},{"VI":711},"Nguyen  Manh Hung",{"id":713,"sortIndex":29,"researcher":21,"roles":714,"affiliations":715,"properties":726},"c0865ff7-9fad-4270-a1cc-14ce88a62023",[],[716],{"id":717,"sortIndex":29,"affiliation":718,"properties":724},"9783c7c8-020c-4b5c-8885-9774b9784be5",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":719,"slug":102,"properties":720,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":721,"address":722,"abbreviation":723},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":725},{"EN":105,"VI":106},{"title":727},{"VI":728},"Vu  Thi Phuong 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Kien",{"id":747,"sortIndex":29,"researcher":21,"roles":748,"affiliations":749,"properties":760},"6f1258f5-bc29-446e-ab57-f70c710dbbbb",[],[750],{"id":751,"sortIndex":29,"affiliation":752,"properties":758},"7007a47a-da8b-453b-9ae0-aa63a0cefdaa",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":753,"slug":102,"properties":754,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":755,"address":756,"abbreviation":757},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":759},{"EN":105,"VI":106},{"title":761},{"VI":762},"Vu  Dinh 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Trieu",{"id":798,"sortIndex":29,"researcher":21,"roles":799,"affiliations":800,"properties":811},"61355d35-dffc-4c19-84f4-2065b4df6112",[],[801],{"id":802,"sortIndex":29,"affiliation":803,"properties":809},"3813566f-65e3-48f2-b033-ca2699d473ad",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":804,"slug":102,"properties":805,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":806,"address":807,"abbreviation":808},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":810},{"EN":105,"VI":106},{"title":812},{"VI":813},"Nguyen  Duc Hai",{"id":815,"sortIndex":29,"researcher":21,"roles":816,"affiliations":817,"properties":828},"2347579c-f7f0-4358-9d15-9eb0fcf413f4",[],[818],{"id":819,"sortIndex":29,"affiliation":820,"properties":826},"f29cc5a6-6497-41b8-94aa-d0e6fd0bd178",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":821,"slug":102,"properties":822,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":823,"address":824,"abbreviation":825},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":827},{"EN":105,"VI":106},{"title":829},{"VI":830},"Nguyen  Thi Thu Huong",{"url":692,"publisher":832,"properties":846},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":833,"slug":10,"properties":834,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":838,"manageAffiliations":839,"indexDatabases":840,"url":27,"thumbnailPath":21,"statistic":841,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":835,"issn":836,"title":837},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":842,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":843,"totalCitation":46,"totalCitationByYear":844,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":845,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":847},{"EN":291,"VI":292},{"total":29,"publishYear":370,"statisticByYear":849},{},"2025-11-25T23:50:05.778+00:00",{"id":852,"createTime":853,"updateTime":854,"relativeEntities":855,"slug":856,"properties":857,"entityType":85,"verifyStatus":20,"verifyTime":870,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":871,"primaryUrl":872,"fullTextUrl":873,"authors":874,"publicationType":273,"publisherRelationship":927,"citationCount":87,"citationInfo":944,"publishDate":946,"publishYear":294,"citationAnalyzeStatus":22,"lastCitationAnalyze":947,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"e769a019-955a-45de-b5d5-87583cba023a","2023-08-22T05:48:30.226+00:00","2026-05-08T23:48:55.130+00:00",[],"M%E1%BB%99t-s%E1%BB%91-y%E1%BA%BFu-t%E1%BB%91-li%C3%AAn-quan-v%E1%BB%9Bi-ch%E1%BA%A5t-l%C6%B0%E1%BB%A3ng-cu%E1%BB%99c-s%E1%BB%91ng-%E1%BB%9F-b%E1%BB%87nh-nh%C3%A2n-cao-tu%E1%BB%95i-c%C3%B3-vi%C3%AAm-lo%C3%A9t-d%E1%BA%A1-d%C3%A0y-t%C3%A1-tr%C3%A0ng-m%E1%BA%A1n-t%C3%ADnh-t%E1%BA%A1i-B%E1%BB%87nh-vi%E1%BB%87n-L%C3%A3o-khoa-Trung-%C6%B0%C6%A1ng",{"gsPaper":858,"keywords":860,"abstract":862,"title":865,"doi":868},{"VOID":859},"14596053431209553315",{"VI":861},"Viêm loét dạ dày tá tràng,chất lượng cuộc sống,người cao tuổi",{"EN":863,"VI":864},"Objective: To explore some factors related to quality of life in the elderly with chronic gastritis and peptic ulcer. Subject and method: A cross-sectional study was performed in 108 patients aged 60 years or older, who was examined and treated at the National Geriatric Hospital. Subjects were interviewed by the unified medical record, their quality of life was assessed using SF-36 questionnaire. Result: The proportion of poor quality of life in the aspect of mental health, physical health and general quality of life in patients aged ≥ 70 years, male, living in rural areas were significantly higher than those in patients aged 60 - 69 years old, female, living in urban areas (p<0.05). The proportion of poor quality of life in the fields of mental health, physical health and general quality of life in patients with duration of gastritis\u002Fpeptic ulcer ≥ 1 year, had clinical symptoms and image of peptic ulcer on endoscopic results were significantly higher than those in patients with diseases’ duration < 1 year, had no clinical symptoms and image of chronic gastritis on endoscopic results (p<0.05). Conclusion: The proportion of patients with poor quality of life associated with mental, physical health and overall were 48.1%, 49.1% and 38%, respectively. Age ≥ 70 years, male, living in rural areas, duration of chronic gastritis\u002Fpeptic ulcer lasts ≥ 1 year, clinical symptoms, image of peptic ulcer on endoscopic results reduced quality of life in elderly patients.","Mục tiêu: Tìm hiểu một số yếu tố liên quan với chất lượng cuộc sống của bệnh nhân cao tuổi có viêm loét dạ dày tá tràng mạn tính. Đối tượng và phương pháp: Mô tả cắt ngang trên 108 bệnh nhân ≥ 60 tuổi có viêm loét dạ dày mạn điều trị tại Bệnh viện Lão khoa Trung ương. Bệnh nhân được phỏng vấn theo mẫu bệnh án thống nhất, chất lượng cuộc sống đánh giá bằng bộ câu hỏi SF-36. Kết quả: Tỷ lệ bệnh nhân có chất lượng cuộc sống không tốt ở các lĩnh vực sức khỏe tinh thần, sức khỏe thể chất và chất lượng cuộc sống chung của nhóm tuổi ≥ 70, giới nam, sống ở nông thôn cao hơn nhóm tuổi 60 - 69, giới nữ, sống ở thành thị có ý nghĩa thống kê với p<0,05. Tỷ lệ bệnh nhân có chất lượng cuộc sống không tốt ở các lĩnh vực sức khỏe tinh thần, sức khỏe thể chất và chất lượng cuộc sống chung của bệnh nhân có thời gian mắc viêm loét loét dạ dày tá tràng ≥ 1 năm, có triệu chứng lâm sàng và tổn thương trên nội soi là loét dạ dày tá tràng cao hơn bệnh nhân có thời gian mắc viêm loét loét dạ dày tá tràng < 1 năm, không có triệu chứng lâm sàng và tổn thương trên nội soi là viêm dạ dày mạn (p<0,05). Kết luận: Tỷ lệ bệnh nhân có chất lượng cuộc sống không tốt liên quan với sức khỏe tinh thần, thể chất và chất lượng cuộc sống không tốt nói chung tương ứng là 48,1%, 49,1% và 38%. Tuổi ≥ 70, giới nam, sống ở nông thôn, thời gian mắc viêm loét loét dạ dày tá tràng kéo dài ≥ 1 năm, có triệu chứng lâm sàng, tổn thương trên nội soi là loét loét dạ dày tá tràng làm giảm chất lượng cuộc sống ở bệnh nhân cao tuổi.",{"EN":866,"VI":867},"Factors related to quality of life in older patients with chronic gastritis and peptic ulcer at National Geriatrics Hospital","Một số yếu tố liên quan với chất lượng cuộc sống ở bệnh nhân cao tuổi có viêm loét dạ dày tá tràng mạn tính tại Bệnh viện Lão khoa Trung ương",{"VOID":869},"10.52389\u002Fydls.v16iDB4.996","2023-08-22T05:48:30.224+00:00",7,"https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F996","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F996\u002F629",[875,897,912],{"id":876,"sortIndex":29,"researcher":21,"roles":877,"affiliations":878,"properties":894},"4f66f069-1f16-41d6-829e-76be09000a93",[],[879],{"id":880,"sortIndex":29,"affiliation":881,"properties":891},"04bf62b6-f465-478e-acac-f572d98c0cbd",{"id":882,"createTime":883,"updateTime":884,"relativeEntities":885,"slug":886,"properties":887,"entityType":112,"verifyStatus":20,"verifyTime":890,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},"ce60c277-3ea6-4200-82a0-ff6db5176caf","2023-05-09T04:30:19.512+00:00","2026-06-18T23:32:17.053+00:00",[],"B%C3%AA%CC%A3nh%20vi%C3%AA%CC%A3n%20La%CC%83o%20khoa%20Trung%20%C6%B0%C6%A1ng",{"title":888},{"VI":889},"Bệnh viện Lão khoa Trung ương","2023-09-28T02:55:35.134+00:00",{"title":892},{"VI":893},"Bệnh viện Lão khoa Trung ương",{"title":895},{"VI":896},"Nguyễn   Trung Anh",{"id":898,"sortIndex":29,"researcher":21,"roles":899,"affiliations":900,"properties":909},"be56b274-be81-4ef4-aa3c-d3180e519a7a",[],[901],{"id":902,"sortIndex":29,"affiliation":903,"properties":907},"45116b80-d71e-4949-9059-a25c90560f3c",{"id":882,"createTime":883,"updateTime":884,"relativeEntities":904,"slug":886,"properties":905,"entityType":112,"verifyStatus":20,"verifyTime":890,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":906},{"VI":889},{"title":908},{"VI":893},{"title":910},{"VI":911},"Nguyễn  Thị Thu Hương",{"id":913,"sortIndex":29,"researcher":21,"roles":914,"affiliations":915,"properties":924},"157e54dd-cfc8-4395-83e7-8d80c2e87941",[],[916],{"id":917,"sortIndex":29,"affiliation":918,"properties":922},"7b9877c8-4612-40fc-8e37-1fa3489507a8",{"id":882,"createTime":883,"updateTime":884,"relativeEntities":919,"slug":886,"properties":920,"entityType":112,"verifyStatus":20,"verifyTime":890,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":921},{"VI":889},{"title":923},{"VI":893},{"title":925},{"VI":926},"Nguyễn  Mạnh Tưởng",{"url":872,"publisher":928,"properties":942},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":929,"slug":10,"properties":930,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":934,"manageAffiliations":935,"indexDatabases":936,"url":27,"thumbnailPath":21,"statistic":937,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":931,"issn":932,"title":933},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":938,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":939,"totalCitation":46,"totalCitationByYear":940,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":941,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":943},{"EN":291,"VI":292},{"total":87,"publishYear":294,"statisticByYear":945},{"2023":87},"2021-12-12","2026-05-08T23:48:55.129+00:00",{"id":949,"createTime":950,"updateTime":951,"relativeEntities":952,"slug":953,"properties":954,"entityType":85,"verifyStatus":20,"verifyTime":963,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":29,"primaryUrl":964,"fullTextUrl":21,"authors":965,"publicationType":273,"publisherRelationship":1007,"citationCount":21,"citationInfo":21,"publishDate":21,"publishYear":675,"citationAnalyzeStatus":22,"lastCitationAnalyze":1024,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"1cab2188-0460-4d54-8407-58ddce169b85","2023-08-22T08:18:00.724+00:00","2026-05-07T23:44:53.141+00:00",[],"Left-ventricular-function-assessed-with-two-dimensional-speckle-tracking-and-three-dimensional-echocardiography-in-patients-with-obstructive-sleep-apnea",{"gsPaper":955,"abstract":957,"title":959,"doi":961},{"VOID":956},"15191552639176022904",{"EN":958},"Objective: To investigate left ventricular function by two-dimensional (2D) speckle tracking and three-dimensional (3D) echocardiography in obstructive sleep apnea (OSA) patients. Subject and method: Patients who were diagnosed with OSA based on the results of full polysomnography and had apnea- hypopnea index values > 5 events\u002Fhour of sleep were included in the study. All patient underwent polysomnography recording. Comprehensive 2-dimensional echocardiography were performed to all subjects according to American Society of Echocardiography guidelines [5], followed by real-time 3D echocardiography. Result: From June 2021 to June 2022, there were 46 OSA patients were included in the study. Mean age of OSA patients 51.3 ± 11.7 years. Men 63% (29\u002F46), women 37% (15\u002F46). The apnea-hypopnea index, percentage of total sleep time with an oxygen saturation level < 90%, arousal index increased in OSA patients. E\u002FE’ increased (12.6 ± 4.3), GLS mildly reduced (-16.5 ± 3.8%) while other echocardiographic parameters were in normal range. Results of ANOVA showed an increase in the following LA parameters on 3D echocardiography according to the levels of OSA severity: LV mass index, 3D maximum LA volume, 3D maximum LA volume index, E\u002FE’ were significantly higher in the severe OSA group compared with the moderate OSA and the mild OSA (p<0.05 for all). There was a decrease in the E’ velocity and global longitudinal strain (GLS) (p<0.05 for all). Conclusion: In patients with obstructive sleep apnea, the severity of OSA was associated with lower E′ velocity, greater E\u002FE′ ratio, larger 3D LV volume, greater LV mass index, and poorer left ventricular global longitudinal strain.",{"VI":960},"Left ventricular function assessed with two-dimensional speckle tracking and three-dimensional echocardiography in patients with obstructive sleep apnea",{"VOID":962},"10.52389\u002Fydls.v17iTA.1635","2023-08-22T08:18:00.723+00:00","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F1635",[966,990],{"id":967,"sortIndex":29,"researcher":21,"roles":968,"affiliations":969,"properties":987},"f8f301f5-1cbf-4b94-88b2-2aa3b4497010",[],[970],{"id":971,"sortIndex":29,"affiliation":972,"properties":985},"942b2b71-eb64-45b6-a317-32ab6e00adaf",{"id":973,"createTime":974,"updateTime":975,"relativeEntities":976,"slug":977,"properties":978,"entityType":112,"verifyStatus":20,"verifyTime":983,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":984},"053efbfe-ef28-4a48-8865-fe5d3062fa75","2023-05-09T03:41:34.226+00:00","2026-06-19T02:13:31.221+00:00",[],"Vietnam%20National%20Heart%20Institute%2C%20Bach%20Mai%20Hospital",{"country":979,"title":980},{"VOID":13},{"EN":981,"VI":982},"Vietnam National Heart Institute, Bach Mai Hospital","Viện Tim Mạch Việt Nam, Bệnh Viện Bạch Mai","2023-08-10T14:10:55.481+00:00",12,{"title":986},{"VI":981},{"title":988},{"VI":989},"Nguyen Thi Thu  Hoai",{"id":991,"sortIndex":29,"researcher":21,"roles":992,"affiliations":993,"properties":1004},"0c4fc52b-5c7f-406c-ba4e-c5dd807a3bd6",[],[994],{"id":995,"sortIndex":29,"affiliation":996,"properties":1002},"650e2d51-6ed1-4084-84d2-5e266c5c4104",{"id":98,"createTime":99,"updateTime":100,"relativeEntities":997,"slug":102,"properties":998,"entityType":112,"verifyStatus":20,"verifyTime":113,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":114},[],{"title":999,"address":1000,"abbreviation":1001},{"EN":105,"VI":106},{"VI":108,"EN":109},{"VOID":111},{"title":1003},{"EN":105,"VI":106},{"title":1005},{"VI":1006},"Pham Nguyen  Son",{"url":964,"publisher":1008,"properties":1022},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1009,"slug":10,"properties":1010,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":1014,"manageAffiliations":1015,"indexDatabases":1016,"url":27,"thumbnailPath":21,"statistic":1017,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":1011,"issn":1012,"title":1013},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":1018,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":1019,"totalCitation":46,"totalCitationByYear":1020,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":1021,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":1023},{"EN":291,"VI":292},"2026-05-07T23:44:53.140+00:00",{"id":1026,"createTime":1027,"updateTime":1028,"relativeEntities":1029,"slug":1030,"properties":1031,"entityType":85,"verifyStatus":20,"verifyTime":1044,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":61,"primaryUrl":1045,"fullTextUrl":1046,"authors":1047,"publicationType":273,"publisherRelationship":1120,"citationCount":21,"citationInfo":21,"publishDate":1137,"publishYear":294,"citationAnalyzeStatus":22,"lastCitationAnalyze":1138,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"5edda000-5018-4b0e-b08c-dcf2716a9cb1","2023-08-22T14:29:26.867+00:00","2026-04-14T23:44:43.752+00:00",[],"Nghi%C3%AAn-c%E1%BB%A9u-m%E1%BB%99t-s%E1%BB%91-%C4%91%E1%BA%B7c-%C4%91i%E1%BB%83m-v%C3%A0-t%C3%A1c-%C4%91%E1%BB%99ng-c%E1%BB%A7a-t%E1%BA%BF-b%C3%A0o-g%E1%BB%91c-ph%C3%A2n-l%E1%BA%ADp-%C4%91%C6%B0%E1%BB%A3c-t%E1%BB%AB-m%C3%B4-m%E1%BB%A1-l%C3%AAn-nguy%C3%AAn-b%C3%A0o-s%E1%BB%A3i-da-tr%C3%AAn-in-vitro",{"gsPaper":1032,"keywords":1034,"abstract":1036,"title":1039,"doi":1042},{"VOID":1033},"6162838150699302496",{"VI":1035},"Tế bào gốc phân lập được từ mô mỡ,nguyên bào sợi da,nuôi cấy tế bào,tăng sinh tế bào",{"EN":1037,"VI":1038},"Objective: To describe some charateristics of Adipose-Derived Stem Cells (ADSCs) and to assess the effects of adipose-derived stem cells (ADSCs) on dermal fibroblasts responses via migration and proliferation in vitro. Subject and method: 10 samples of dermal fibroblasts and ADSCs were isolated from skin and adipose tissues of 10 healthy persons, who hospitalized at Plastic surgery Department, National Burn Hospital for plastic surgeries from June to December, 2020. We counted ADSCs after isolation and determined the morphological characterisation of ADSCs afer 72 hours, 7 days, 10 days of culture and chromosomes characterisation of ADSCs at the 5th passage. We also determined the effects of ADSCs on the proliferation and migration of dermal fibroblasts in vitro. Result: The average number of ADSCs after isolation was 2.63×106 ± 1.6×106 cells\u002F1 gram of adipose tissue (min - max: 2.5 - 2.7×106) and the percentage of healthy ADSCS was 96.6 ± 1.5% (min - max: 96.2 - 97.5). After 72 hours of culture, ADSCs adhered to the surface of cell culture plate. After 7 days of culture, ADSCs spreading was promoted by coating the cell culture plate. After 10 days of culture, the proliferation of ADSCs occurred strongly, they coved more than 80% of the surface area of cell culture plate. The ADSCs still had normal chromosomal structure in the 5th passage. The proliferation and migration rate of dermal fibroblasts in the culture medium which supplemented with ADSCs -conditionned medium (ADSCs-CM) was higher than that in the control group. These rates were the highest when replacing 50% of the culture medium of dermal fibroblasts with ADSCs-CM. Conclusion: The ADSCS that we isolated had all the morphological characterisation of the stem cells and still retained the normal chromosomal structure in the 5th passage. In vitro, ADSCs stimulated the proliferation and migration of dermal fibroblasts.","Mục tiêu: Mô tả đặc điểm của tế bào gốc phân lập được từ mô mỡ (TBGM) và đánh giá tác động của TBGM lên khả năng tăng sinh, di cư của nguyên bào sợi da (NBS) trên invitro. Đối tượng và phương pháp: Chúng tôi đã sử dụng 10 mẫu NBS và mô mỡ của 10 bệnh nhân (BN) khỏe mạnh làm phẫu thuật thẩm mỹ tại Bệnh viện Bỏng Quốc gia từ tháng 6 năm 2020 đến tháng 12 năm 2020, để triển khai nghiên cứu đặc điểm của TBGM (số lượng TBGM sau phân lập, hình dáng và đặc tính của TBGM sau nuôi cấy tăng sinh ở các thời điểm 72 giờ, 7 ngày và 10 ngày, đặc điểm của bộ nhiễm sắc thể của thế hệ TBGM sau 5 lần cấy chuyển - P5) và tác động của TBGM lên khả năng tăng sinh và di cư của NBS trên invitro. Kết quả: Số lượng TBGM thu được sau khi xử lý mẫu mô là 2,63×106 ± 1,6×106 tế bào\u002Fgram mô mỡ (min - max : 2,5 - 2,7×106), trong đó tỷ lệ TBGM sống là 96,6 ± 1,5% (min - max : 96,2 - 97,5). Sau 72 giờ nuôi cấy, nhiều TBGM đã bám vào bề mặt đĩa nuôi cấy, sau 7 ngày nuôi cấy TBGM có hình dạng tương tự NBS, mọc đơn lớp. Sau 10 ngày nuôi cấy, TBGM phát triển mạnh, đạt yêu cầu cấy chuyển (mật độ tế bào đạt trên 80% diện tích che phủ). Sau 5 lần cấy chuyển, tất cả 10 mẫu TBGM đều có cấu trúc bộ nhiễm sắc thể bình thường. Tốc độ tăng sinh và di cư của NBS trong môi trường nuôi cấy có bổ sung dịch chiết của TBGM tăng cao hơn so với nhóm chứng và tốc độ này là cao nhất khi bổ sung 50% dịch chiết từ TBGM vào môi trường nuôi cấy NBS. Kết luận: Chúng tôi đã phân lập thành công TBGM từ mô mỡ, TBGM phân lập được có đầy đủ đặc điểm hình thái và đặc tính của tế bào gốc và giữ nguyên cấu trúc nhiễm sắc thể sau 5 lần cấy chuyển. Trong nghiên cứu in vitro, TBGM có tác dụng kích thích sự tăng sinh và di cư của NBS.",{"EN":1040,"VI":1041},"Studying some charateristics and the effects of adipose-derived stem cells (ADSCs) on dermal fibroblast in vitro","Nghiên cứu một số đặc điểm và tác động của tế bào gốc phân lập được từ mô mỡ lên nguyên bào sợi da trên in vitro",{"VOID":1043},"10.52389\u002Fydls.v16i6.855","2023-08-22T14:29:26.866+00:00","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F855","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F855\u002F971",[1048,1079,1099],{"id":1049,"sortIndex":29,"researcher":21,"roles":1050,"affiliations":1051,"properties":1076},"c1d9caa0-50d8-4e04-822f-ac0754372b21",[],[1052],{"id":1053,"sortIndex":29,"affiliation":1054,"properties":1073},"16de9888-c74d-47a2-9ad0-d487e140a605",{"id":1055,"createTime":1056,"updateTime":1057,"relativeEntities":1058,"slug":1059,"properties":1060,"entityType":112,"verifyStatus":20,"verifyTime":1070,"verifyNote":21,"syncStatus":22,"languages":1071,"translateLanguages":21,"viewCount":1072},"01b1968a-9a0b-4420-b4b3-bdb698ef89d4","2023-05-19T07:42:09.167+00:00","2026-04-29T17:49:25.016+00:00",[],"B%E1%BB%87nh-vi%E1%BB%87n-B%E1%BB%8Fng-Qu%E1%BB%91c-gia-L%C3%AA-H%E1%BB%AFu-Tr%C3%A1c",{"country":1061,"title":1062,"address":1065,"abbreviation":1068},{"VOID":13},{"EN":1063,"VI":1064},"National Burn Hospital Le Huu Trac","Bệnh viện Bỏng Quốc gia Lê Hữu Trác",{"VI":1066,"EN":1067},"263 Phùng Hưng, Phúc La, Hà Đông, Hà Nội, Việt Nam","263 Phung Hung, Phuc La, Ha Dong, Hanoi, Vietnam",{"VOID":1069},"BV Bỏng Quốc gia","2023-08-08T15:48:06.804+00:00",[527,389],15,{"title":1074},{"VI":1075},"Bệnh viện Bỏng Quốc gia ",{"title":1077},{"VI":1078},"Nguyễn Thị  Hương",{"id":1080,"sortIndex":29,"researcher":21,"roles":1081,"affiliations":1082,"properties":1096},"340b95db-2cf5-458b-8ec6-3aef0835d3b9",[],[1083],{"id":1084,"sortIndex":29,"affiliation":1085,"properties":1093},"68e3ded6-e680-42cb-b87a-644dc2f571ae",{"id":1055,"createTime":1056,"updateTime":1057,"relativeEntities":1086,"slug":1059,"properties":1087,"entityType":112,"verifyStatus":20,"verifyTime":1070,"verifyNote":21,"syncStatus":22,"languages":1092,"translateLanguages":21,"viewCount":1072},[],{"country":1088,"title":1089,"address":1090,"abbreviation":1091},{"VOID":13},{"EN":1063,"VI":1064},{"VI":1066,"EN":1067},{"VOID":1069},[527,389],{"title":1094},{"VI":1095},"Bệnh viện Bỏng Quốc gia",{"title":1097},{"VI":1098},"Đinh Văn  Hân",{"id":1100,"sortIndex":29,"researcher":21,"roles":1101,"affiliations":1102,"properties":1115},"a8aae5d5-2908-4020-8073-3cfa10a0b8d3",[],[1103],{"id":1104,"sortIndex":29,"affiliation":1105,"properties":1113},"5762d3e7-868c-434c-b40b-111ce0eda352",{"id":1055,"createTime":1056,"updateTime":1057,"relativeEntities":1106,"slug":1059,"properties":1107,"entityType":112,"verifyStatus":20,"verifyTime":1070,"verifyNote":21,"syncStatus":22,"languages":1112,"translateLanguages":21,"viewCount":1072},[],{"country":1108,"title":1109,"address":1110,"abbreviation":1111},{"VOID":13},{"EN":1063,"VI":1064},{"VI":1066,"EN":1067},{"VOID":1069},[527,389],{"title":1114},{"VI":1095},{"gsAuthor":1116,"title":1118},{"VOID":1117},"tMYM4F4AAAAJ",{"VI":1119},"Nguyễn Tiến  Dũng",{"url":1045,"publisher":1121,"properties":1135},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1122,"slug":10,"properties":1123,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":1127,"manageAffiliations":1128,"indexDatabases":1129,"url":27,"thumbnailPath":21,"statistic":1130,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":1124,"issn":1125,"title":1126},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":1131,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":1132,"totalCitation":46,"totalCitationByYear":1133,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":1134,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":1136},{"EN":291,"VI":292},"2021-08-30","2026-04-14T23:44:43.751+00:00",{"id":1140,"createTime":1141,"updateTime":1142,"relativeEntities":1143,"slug":1144,"properties":1145,"entityType":85,"verifyStatus":20,"verifyTime":1158,"verifyNote":86,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":52,"primaryUrl":1159,"fullTextUrl":1160,"authors":1161,"publicationType":273,"publisherRelationship":1226,"citationCount":21,"citationInfo":21,"publishDate":1243,"publishYear":294,"citationAnalyzeStatus":22,"lastCitationAnalyze":1244,"indexDatabases":21,"openAccess":21,"references":21,"isForceReanalyzing":296},"1e62cb1b-5bc0-494d-8321-16467c90de1f","2023-08-22T14:17:49.130+00:00","2025-07-18T23:43:44.189+00:00",[],"N%E1%BB%93ng-%C4%91%E1%BB%99-adiponectin-v%C3%A0-leptin-huy%E1%BA%BFt-thanh-tr%C3%AAn-b%E1%BB%87nh-nh%C3%A2n-v%E1%BA%A3y-n%E1%BA%BFn-m%E1%BA%A3ng-t%E1%BA%A1i-B%E1%BB%87nh-vi%E1%BB%87n-Da-li%E1%BB%85u-Th%C3%A0nh-ph%E1%BB%91-H%E1%BB%93-Ch%C3%AD-Minh",{"gsPaper":1146,"keywords":1148,"abstract":1150,"title":1153,"doi":1156},{"VOID":1147},"9578537247564471836",{"VI":1149},"Vảy nến mảng,leptin,adiponectin",{"EN":1151,"VI":1152},"Objective: To evaluate of serum adiponectin, leptin levels and related factors in plaque psoriasis patients and controls at Ho Chi Minh City Dermatology Hospital. Subject and method: 48 cases of plaque psoriasis and 48 healthy people at Ho Chi Minh City Dermatology Hospital. Plaque psoriasis is diagnosed based on clinical manifestation and severity is calculated based on PASI score. Adiponectin level was measured by immunoturbidimetric assay and leptin was measured by sandwich ELISA. Result: The median of serum adiponectin level in the patient group was 4.27 (2.68 - 6.38) μg\u002Fml lower than which of the control group was 5.39 (3.66 - 7.98) μg\u002Fml, p=0.036. In the female subgroup, the serum adiponectin level of the patient group was 5.44 (3.84 - 6.64) μg\u002Fml, that was also lower than that of the control group which was 7.02 (4.83 - 10.4) μg\u002Fml (p=0.016). There was no statistically significant difference in serum leptin level in the psoriatic group and the control group (p=0.985). Serum leptin level was related to PASI severtity. Conclusion: The serum adiponectin level in the patient group was statistically significant lower than the control group, in general and in the female subgroup. There was no difference in leptin concentration between the disease group and the control group. Serum leptin concentration of psoriatic patients was related to PASI severity.","Mục tiêu: Đánh giá nồng độ adiponectin, leptin huyết thanh và các yếu tố liên quan trên bệnh nhân vảy nến mảng và nhóm chứng tại Bệnh viện Da liễu Thành phố Hồ Chí Minh. Đối tượng và phương pháp: 48 ca vảy nến mảng và 48 người khoẻ mạnh tại Bệnh viện Da liễu Thành phố Hồ Chí Minh. Vảy nến mảng được chẩn đoán dựa trên lâm sàng và phân độ nặng theo thang điểm PASI. Nồng độ adiponectin được đo bằng phương pháp miễn dịch đo độ đục và leptin được đo bằng phương pháp ELISA sandwich. Kết quả: Nồng độ adiponectin huyết thanh ở nhóm bệnh là 4,27 (2,68 - 6,38) μg\u002Fml thấp hơn nhóm chứng là 5,39 (3,66 - 7,98) μg\u002Fml, p=0,036. Ở nữ, nồng độ adiponectin huyết thanh của nhóm bệnh là 5,44 (3,84 - 6,64) μg\u002Fml cũng thấp hơn nhóm chứng là 7,02 (4,83 - 10,4) μg\u002Fml (p=0,016). Nồng độ leptin huyết thanh nhóm bệnh và nhóm chứng không có sự khác biệt có ý nghĩa thống kê (p=0,985). Nồng độ leptin huyết thanh bệnh nhân vảy nến mảng liên quan với độ nặng theo PASI. Kết luận: Nồng độ adiponectin huyết thanh ở nhóm bệnh thấp hơn nhóm chứng, tương tự ở nữ nồng độ này ở nhóm bệnh cũng thấp hơn nhóm chứng. Không có sự khác biệt nồng độ leptin giữa nhóm bệnh và nhóm chứng. Bệnh nhân vảy nến mảng có nồng độ leptin huyết thanh liên quan với mức độ nặng của bệnh.",{"EN":1154,"VI":1155},"Serum adiponectin and leptin levels of plaque psoriasis patients in Ho Chi Minh City Hospital of Dermatology and Venereology","Nồng độ adiponectin và leptin huyết thanh trên bệnh nhân vảy nến mảng tại Bệnh viện Da liễu Thành phố Hồ Chí Minh",{"VOID":1157},"10.52389\u002Fydls.v16i5.806","2023-08-22T14:17:49.129+00:00","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fview\u002F806","https:\u002F\u002Ftcydls108.benhvien108.vn\u002Findex.php\u002FYDLS\u002Farticle\u002Fdownload\u002F806\u002F931",[1162,1190,1208],{"id":1163,"sortIndex":29,"researcher":21,"roles":1164,"affiliations":1165,"properties":1187},"2452b4c1-f738-4d0b-9fa5-2a3b9a9300ec",[],[1166],{"id":1167,"sortIndex":29,"affiliation":1168,"properties":1184},"10ade41f-1a37-49ea-9c2b-01e1772fc55e",{"id":1169,"createTime":1170,"updateTime":1171,"relativeEntities":1172,"slug":1173,"properties":1174,"entityType":112,"verifyStatus":20,"verifyTime":1181,"verifyNote":1182,"syncStatus":22,"languages":1183,"translateLanguages":21,"viewCount":37},"c1c48c5a-3314-4926-b294-868819058794","2023-05-09T04:29:05.403+00:00","2026-06-19T02:29:40.368+00:00",[],"Tr%C6%B0%E1%BB%9Dng%20%C4%90%E1%BA%A1i%20h%E1%BB%8Dc%20Y%20Khoa%20Ph%E1%BA%A1m%20Ng%E1%BB%8Dc%20Th%E1%BA%A1ch",{"country":1175,"title":1176,"abbreviation":1179},{"VOID":13},{"EN":1177,"VI":1178},"Pham Ngoc Thach University of Medicine","Trường Đại học Y Khoa Phạm Ngọc Thạch",{"VOID":1180},"PNT","2023-08-17T07:04:09.382+00:00","Remove verified status because of duplicating",[527,389],{"title":1185},{"VI":1186},"Đại học Y khoa Phạm Ngọc Thạch",{"title":1188},{"VI":1189},"Trương Trần Bích  Ngân",{"id":1191,"sortIndex":29,"researcher":21,"roles":1192,"affiliations":1193,"properties":1203},"10fe9035-1d97-4930-bdd2-c1d1c7cffc13",[],[1194],{"id":21,"sortIndex":29,"affiliation":1195,"properties":21},{"id":1196,"createTime":1197,"updateTime":1197,"relativeEntities":1198,"slug":1199,"properties":1200,"entityType":112,"verifyStatus":22,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":29},"2fd8a18c-b29c-4773-8868-b47c7e8a3202","2024-04-14T19:49:38.158+00:00",[],"B%E1%BB%87nh-vi%E1%BB%87n-Da-li%E1%BB%85u-Th%C3%A0nh-ph%E1%BB%91-H%E1%BB%93-Ch%C3%AD-Minh-",{"title":1201},{"EN":1202},"Bệnh viện Da liễu Thành phố Hồ Chí Minh ",{"gsAuthor":1204,"title":1206},{"VOID":1205},"Xu-MrfgAAAAJ",{"VI":1207},"Nguyễn Thanh  Hùng",{"id":1209,"sortIndex":29,"researcher":21,"roles":1210,"affiliations":1211,"properties":1223},"05b411cb-1829-4d44-b8fb-6880aad30cbe",[],[1212],{"id":1213,"sortIndex":29,"affiliation":1214,"properties":1221},"0c935161-9417-4702-a26b-02d59456fc7f",{"id":1169,"createTime":1170,"updateTime":1171,"relativeEntities":1215,"slug":1173,"properties":1216,"entityType":112,"verifyStatus":20,"verifyTime":1181,"verifyNote":1182,"syncStatus":22,"languages":1220,"translateLanguages":21,"viewCount":37},[],{"country":1217,"title":1218,"abbreviation":1219},{"VOID":13},{"EN":1177,"VI":1178},{"VOID":1180},[527,389],{"title":1222},{"VI":1186},{"title":1224},{"VI":1225},"Ngô Minh  Vinh",{"url":1159,"publisher":1227,"properties":1241},{"id":6,"createTime":7,"updateTime":8,"relativeEntities":1228,"slug":10,"properties":1229,"entityType":19,"verifyStatus":20,"verifyTime":21,"verifyNote":21,"syncStatus":22,"languages":21,"translateLanguages":21,"viewCount":23,"subjectFields":1233,"manageAffiliations":1234,"indexDatabases":1235,"url":27,"thumbnailPath":21,"statistic":1236,"gsStatistic":21,"type":21,"analyzePriority":21},[],{"country":1230,"issn":1231,"title":1232},{"VOID":13},{"VOID":15},{"EN":17,"VI":18},[],[],[],{"impactFactor":29,"impactFactorByYear":1237,"i10Index":29,"i10IndexLast5Year":29,"totalPublication":35,"totalPublicationByYear":1238,"totalCitation":46,"totalCitationByYear":1239,"totalCitationPerPublication":53,"totalCitationPerPublicationByYear":1240,"hindexLast5Year":61,"hindex":61},{"2020":29,"2021":31,"2022":31,"2023":32,"2024":33,"2025":34},{"2017":37,"2018":38,"2019":39,"2020":40,"2021":41,"2022":42,"2023":43,"2024":44,"2025":45},{"2018":23,"2019":48,"2020":49,"2021":50,"2022":49,"2023":51,"2025":52},{"2018":55,"2019":56,"2020":57,"2021":58,"2022":59,"2023":60,"2025":31},{"title":1242},{"EN":291,"VI":292},"2021-07-31","2025-07-18T23:43:44.188+00:00"]