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other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. 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Along with blood, plasma and urine, saliva is of increasing interest as an alternative matrix for HBM. This paper reviews studies that measure salivary background levels of hazardous substances, elevated levels after environmental or occupational exposure, as well as references which deal with physiological and toxicokinetic behaviour of saliva and salivary parameters, respectively. The studies revealed that the determination of biomarkers in saliva is a promising approach for HBM, even if only few substances showed a satisfying correlation with exposure data or established biomonitoring matrices such as blood, plasma and urine. Saliva has been proven to be particularly suitable for substances of low molecular weight such as organic solvents, selected pesticides, cotinine, and for some specific trace elements. Besides several advantages, serious problems and limitations were identified. Above all, the complex interactions between substance properties, sampling procedure, sample preparation, measurement techniques or individual factors, and the salivary analyte level are discussed. A major conclusion of the review is that more scientific studies are needed in order to systematically collect data on parameters, influencing salivary analyte levels. Crucially required is a harmonisation of the sampling as well as the sample preparation techniques and procedures, which is indispensable to achieve an overall comparability and interpretability of salivary biomarker levels.",{"EN":1042},"Saliva as a matrix for human biomonitoring in occupational and environmental medicine",{"VOID":1044},"Abdollahi M, Mostafalou S, Pournourmohammadi S, Shadnia S (2004) Oxidative stress and cholinesterase inhibition in saliva and plasma of rats following subchronic exposure to Malathion. Comp Biochem Physiol C: Toxicol Pharmacol 137:29–34\nAbdollahi M, Balali-Mood M, Akhgari M, Jannat B, Kebriaeezadeh A, Nikfar S (1996) A Survey of cholinesterase activity in healthy and organophosphate exposed populations. Iran J Med Sci 21:63–68\nAğaoğlu G, Arun T, Izgi B, Yarat A (2001) Nickel and chromium levels in the saliva and serum of patients with fixed orthodontic appliances. Angle Orthod 71:375–379\nAmini F, Jafari A, Amini P, Sepasi S (2012) Metal ion release from fixed orthodontic appliances—an in vivo study. Eur J Orthod 34:126–130\nAps JK, Martens LC (2005) Review: The physiology of saliva and transfer of drugs into saliva. Forensic Sci Int 150:119–131\nAtkinson JC, Dawes C, Ericson T, Fox PC, Gandara BK, Malamud D, Mandel ID, Navazesh M, Tabak LA (1993) Guidelines for saliva nomenclature and collection. Ann NY Acad Sci 694:xi–xii\nAufrich C, Tenner W, Salzer HR, Khoss AE, Wurst E, Herkner K (1992) Salivary IgA concentration is influenced by the saliva collection method. Eur J Clin Chem Clin Biochem 30:81–83\nAustralian Standards, AS 4760 (2006) Procedures for specimen collection and the detection and quantitation of drugs in oral fluid\nAyinampudi BK, Narsimhan MJ (2012) Salivary copper and zinc levels in oral pre-malignant and malignant lesions. Oral Maxillofac Pathol 16:178–182\nBales CW, Freeland-Graves JH, Askey S, Behmardi F, Pobocik RS, Fickel JJ, Greenlee P (1990) Zinc, magnesium, copper, and protein concentrations in human saliva: age- and sex-related differences. Am J Clin Nutr 51:462–469\nBarbosa F Jr, Tanus-Santos JE, Gerlach RF, Parsons PJ (2005) A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs. Environ Health Perspec 113:1669–1674\nBaričević M, Mravak-Stipetić M, Stanimirović A, Blanuša M, Kern J, Lončar B, Andabak A, Baričević D (2011) Salivary concentrations of nickel and chromium in patients with burning mouth syndrome. 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Ann NY Acad Sci 694:311–313\nShannon IL, Prigmore JR, Chauncey HH (1962) Modified Carlson-Crittenden device for the collection of parotid fluid. J Dent Res 41:778–783\nShern RJ, Fox PC, Cain JL, Li SH (1990) A method for measuring the flow of saliva from the minor salivary glands. J Dent Res 69:1146–1149\nShern RJ, Fox PC, Li SH (1993) Influence of age on the secretory rates of the human minor salivary glands and whole saliva. Arch Oral Biol 38:755–761\nShigemi T, Tanaka T, Hayashida Y, Maki K (2008) Study of salivary strontium and silver concentrations in primary school children related to dental caries. Biol Trace Elem Res 123:80–90\nSiegel IA (1992) Use of saliva to monitor drug concentrations. In: Sreebny LM (ed) The salivary system. CRC Press, Boca Raton, pp 157–202\nSighinolfi GP, Gorgoni C, Bonor O, Cantoni E, Martelli M, Simonetti L (1989) Comprehensive determination of trace elements in human saliva by ETA-AAS. Mikrochim Acta 1:171–179\nSilva MJ, Barr DB, Reidy JA, Kato K, Malek NA, Hodge CC, Hurtz D, Calafat AM, Needham LL, Brock JW (2003) Glucuronidation patterns of common urinary and serum monoester phthalate metabolites. Arch Toxicol 77:561–567\nSilva MJ, Barr DB, Reidy JA, Malek NA, Hodge CC, Caudill SP, Brock JW, Needham LL, Calafat AM (2004) Urinary levels of seven phthalate metabolites in the US population from the national health and nutrition examination survey (NHANES) 1999–2000. Environ Health Perspect 112:331–338\nSilva MJ, Reidy JA, Samandar E, Herbert AR, Needham LL, Calafat AM (2005) Detection of phthalate metabolites in human saliva. Arch Toxicol 79:647–652\nSlomiany BL, Murty VL, Slomiany A (1985) Salivary lipids in health and disease. Prog Lipid Res 24:311–324\nSlowey PD (2013) Commercial saliva collections tools. J Calif Dent Assoc 41(97–9):102–105\nSmidt D, Torpet LA, Nauntofte B, Heegaard KM, Pedersen AM (2010) Associations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older people community. Dent Oral Epidemiol 38:422–435\nSmith JN, Wang J, Lin Y, Klohe EM, Timchalk C (2012) Pharmacokinetics and pharmacodynamics of chlorpyrifos and 3, 5, 6-trichloro-2-pyridinol in rat saliva after chlorpyrifos administration. Toxicol Sci 130:245–256\nSmith JN, Wang J, Lin Y, Timchalk C (2010) Pharmacokinetics of the chlorpyrifos metabolite 3, 5, 6-trichloro-2-pyridinol (TCPy) in rat saliva. Toxicol Sci 113:315–325\nSonesson M (2011) On minor salivary gland secretion in children, adolescents and adults. Swed Dent J Suppl 215:9–64\nSpeirs RL (1984) Secretion of saliva by human lip mucous glands and parotid glands in response to gustatory stimuli and chewing. 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J Toxicol Environ Health A 67:635–650\nTimchalk C, Poet TS, Lin Y, Weitz KK, Zhao R, Thrall K (2001) Development of an integrated microanalytical system for analysis of lead in saliva and linkage to a physiologically based pharmaco-kinetic model describing saliva secretion. Am Ind Hyg Assoc J 62:295–302\nTomita M, Nishimura N (1982) Using salvia to estimate human exposure to organic solvents. Bull Tokyo Dent Coll 23:175–188\nTruelove EL, Bixler D, Merritt AD (1967) Simplified method for collection of pure submandibular saliva in large volumes. J Dent Res 46:1400–1403\nTurnlund JR, Keen CL, Smith RG (1990) Copper status and urinary and salivary copper in young men at three levels of dietary copper. Am J Clin Nutr 51:658–664\nvan Vunakis H, Tashkin DP, Rigas B, Simmons M, Gjika HB, Clark VA (1989) Relative sensitivity and specificity of salivary and serum cotinine in identifying tobacco-smoking status of self-reported nonsmokers and smokers of tobacco and\u002For Marijuana. Arch Environ Health 44:53–58\nWang VS, Chang TY, Lai CC, Chen SY, Huang LC, Chao KP (2012) Application of solid phase microextraction on dental composite resin analysis. J Chromatogr B 903:88–94\nWang VS, Lu MY (2009) Application of solid-phase microextraction and gas chromatography-mass spectrometry for measuring chemicals in saliva of synthetic leather workers. J Chromatogr B 877:24–32\nWang D, Du X, Zheng W (2008) Alteration of saliva and serum concentrations of manganese, copper, zinc, cadmium and lead among career welders. Toxicol Lett 176:40–47\nWatanabe K, Tanaka T, Shigemi T, Saeki K, Fujita Y, Morikawa K, Nakashima H, Takahashi S, Watanabe S, Maki K (2011) Al and Fe levels in mixed saliva of children related to elution behavior from teeth and restorations. J Trace Elem Med Biol 25:143–148\nWatanabe K, Tanaka T, Shigemi T, Hayashida Y, Maki K (2009) Mn and Cu concentrations in mixed saliva of elementary school children in relation to sex, age, and dental caries. J Trace Elem Med Biol 23:93–99\nWatanabe M, Asatsuma M, Ikui A, Ikeda M, Yamada Y, Nomura S, Igarashi A (2005) Measurements of several metallic elements and matrix metalloproteinases (MMPs) in saliva from patients with taste disorder. Chem Senses 30:121–125\nWhite MA, O’Hagan SA, Wright AL, Wilson HK (1992) The measurement of salivary cadmium by electrothermal atomic absorption spectrophotometry and its use as a biological indicator of occupational exposure. J Expo Anal Environ Epidemiol 2:195–206\nWilhelm M, Pesch A, Rostek U, Begerow J, Schmitz N, Idel H, Ranft U (2002) Concentrations of lead in blood, hair and saliva of German children living in three different areas of traffic density. Sci Total Environ 297:109–118\nWolff A, Begleiter A, Moskona D (1997) A novel system of human submandibular\u002Fsublingual saliva collection. J Dent Res 76:1782–1786\nYonamine M, Tawil N, Moreau RL, Silva OA (2003) Solid-phase micro-extraction-gas chromatography-mass spectrometry and headspace-gas chromatography of tetrahydrocannabinol, amphetamine, methamphetamine, cocaine and ethanol in saliva samples. J Chromatogr B 789:73–78\nZachariadis GA, Kapsimali DC (2008) Effect of sample matrix on sensitivity of mercury and methylmercury quantitation in human urine, saliva, and serum using GC-MS. J Sep Sci 31:3884–3893\nZahir S, Sarkar S (2006) Study of trace elements in mixed saliva of caries free and caries active children. Official publication of Indian Society of Pedodontics and Preventive Dentistry 24:27–29\nZaichick VA, Tsyb AF, Bagirov S (1995) Neutron activation analysis of saliva application in clinical chemistry, environmental and occupational toxicology. J Radioanal Nucl Chem 195:123–132\nZhang Z, Pawliszyn J (1993) Headspace solid-phase microextraction. 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secondary analysis of data from a national survey was carried out in order to assess the number of industrial workers exposed to noise and other adverse working conditions. This permitted us to study correlations with parameters of health. More than half of the male blue collar workers in industry and building trades (sample n = 311) reported a great deal of noise. Dirty work and strenuous physical activity were also frequently mentioned. Noise exposure is often present together with exposure to stench and dirty and dangerous work. A weak correlation exists between reported noise exposure and experienced ill-being and diminished satisfaction with their own health. This observed relationship probably underestimates the true risks.",{"EN":1188},"Non-auditory effects of noise in industry",{"VOID":1190},"Elsner G (1977) Lärmquellen and Möglichkeiten ihrer Bekämpfung im Urteil von Betriebsraten und Arbeitnehmern. Bundesministerium für Arbeit and Sozialordnung, Bonn\nElsner G, Preiser K (1978) Lärm als Leitbelastung. Zbl Arbeitsmed 28:75–78\nManninen O (1977) Environmental factors and employees' discomfort in three machine industry plants. University Tampere, Finland (Public Health Sciences M 32)\nVolkholz V (1977) Belastungsschwerpunkte und Praxis der Arbeitssicherheit. Bundesministerium für Arbeit und Sozialordnung, Bonn",{"VOID":1192},"10.1007\u002FBF00377890","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002FBF00377890",[1195,1210,1223],{"id":1196,"sortIndex":23,"researcher":22,"roles":1197,"affiliations":1198,"properties":1207},"40258c35-9ce6-43ed-848e-b3529ea9099f",[1054],[1199],{"id":1200,"sortIndex":23,"affiliation":1201,"properties":22},"d0bfe3e2-7d4e-4420-a97d-90bfa9dc648a",{"id":1200,"createTime":22,"updateTime":22,"relativeEntities":1202,"slug":22,"properties":1203,"entityType":22,"verifyStatus":22,"verifyTime":22,"verifyNote":22,"languages":22,"translateLanguages":22,"viewCount":22,"url":22,"parentIds":1206,"statistic":22},[],{"title":1204},{"VI":1205},"Coronel Laboratory for Occupational and Evironmental Health, Faculty of Medicine, University of Amsterdam, AMC, AZ Amsterdam, The Netherlands",[],{"title":1208},{"VI":1209},"J. H. A. M. 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steel (SS) welders usually spend some of their working time grinding, to finish and smoothen the welding groove. The aim of this study was to investigate possible relations between the concentrations of nickel (Ni) and chromium (Cr) in the work atmosphere generated by grinders grinding SS, and to compare the air levels to the levels of Cr and Ni in their biological fluids. Hereby, it might be possible to identify the contribution of grinding to the levels of Cr and Ni in biological fluids in SS welders. Also the airborne levels of Cr and Ni in SS grinders were compared to corresponding levels in SS welders. The subjects examined in this study were selected among SS grinders not performing welding. Nine grinders were monitored for 1 workweek, measuring Cr and Ni in air, blood and urine. They were questioned about their exposure to Cr and Ni during their working careers. Air levels of total Cr up to 95 μg\u002Fm3 and Ni levels up to 25 μg\u002Fm3 were measured. ChromiumVI (CrVI) was detectable only in five air samples; the levels in the remaining samples were below the detection limit. The levels of Cr in blood and urine were also low. The levels of Ni in urine were close to those for MMA and MIG\u002FMAG SS welders. In spite of high levels of total Cr and Ni observed in air, the levels found in biological fluids were low. The Cr levels in more than 50% of the whole blood and red cell samples and about 1\u002F3 of the Cr–plasma levels were below the detection limits. The mean blood levels for Cr were 0.43, 0.60 and 0.35 μg\u002Fl, in whole blood, plasma and red cells, respectively. The mean levels for Cr in the urine was 1.6, 1.4 and 1.4 μg\u002Fg creatinine for the first void, just before and just after work. For Ni the mean blood levels were 0.87 μg\u002Fl in whole blood and 0.68 μg\u002Fl in plasma. The mean levels and ranges of Ni from the first void, just before and after work in urine were 3.79 μg\u002Fg creatinine, 3.39 and 4.56, respectively. The Cr concentrations found in whole blood, plasma and red cells were approximately the same as those found in the unexposed controls and among TIG SS welders, while the urinary levels were somewhat higher, but still lower than in the welders applying other welding techniques. The mean levels of Ni in the urine of grinders were higher than those of welders, except for SS welders welding the MIG\u002FMAG-method. SS Grinding seems not to contribute significantly to the uptake of Cr, which may be explained by the fact that most of Cr in the air is present in the metallic (0-valent) or trivalent form, and hardly any as CrVI, and therefore hardly being taken up in the airways. The grinders’ uptake of Ni seems to take place to the same extent as in SS welders.",{"EN":1297},"Monitoring of chromium and nickel in biological fluids of grinders grinding stainless steel",{"VOID":1299},"Araki S, Aono H (1989) Effects of water restriction and water loading on daily urinary excretion of heavy metals and organic substances in metal workers. Br J Ind Med 46:389–392\nKarlsen JT, Farrants G, Torgrimsen T, Reith A (1992) Chemical composition and morphology of welding fume particles and grinding dusts. Am Ind Hyg Assoc J 53:290–297\nKarlsen JT, Torgrimsen T, Langård S, Farrants G, Reith A (1996) Exposure to solid aerosols during ordinary MIG\u002FMAG and TIG welding operations on stainless steel. Occup Hyg 3:377–387\nKoponen M, Gustafson T, Kalliomäki P-L, Kalliomäki K, Moilanen M (1981) Grinding dusts of alloyed steel and hard metal. Ann occup Hyg 24:191–204\nSchaller KH, Zober A (1982) Renale Ausscheidungen toxikologisch relevanter Metalle bei beruflich unbelasteten Personen. Das Ärztliche Laboratorium 28:209–214\nSchellhas H (1984) Medizinische Untersuchungen zur Gefährdung durch chromnickelhaltige Stäube in der Weiterverarbeitung von Edelstahl. Stahl u. Eisen 104:667–669\nStridsklev IC, Schaller KH, Raithel HJ, Hemmingsen B, Langård S (1993) Biologic monitoring of chromium and nickel among stainless steel welders using the manual metal arc method. Int Arch Occup Environ Health 65:209–219\nStridsklev IC, Schaller KH, Raithel HJ, Hemmingsen B, Langård S (1994) Biologic monitoring of chromium and nickel among stainless steel welders using the tungsten inert gas method. J Occup Med Toxicol 3:43–557\nStridsklev IC, Schaller KH, Langård S (2004) Monitoring of chromium and nickel in biological fluids of stainless steel welders using the flux cored wire (FCW) welding method. Int Arch Occup Environ Health 77:587–591\nTorgrimsen T (1982) Analysis of chromium. In: Langård S (ed) Biological and environmental aspects of chromium. Elsevier, Amsterdam, pp 149–160",{"VOID":1301},"10.1007\u002Fs00420-006-0142-3","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00420-006-0142-3",[1304,1319,1334],{"id":1305,"sortIndex":23,"researcher":22,"roles":1306,"affiliations":1307,"properties":1316},"ac34039a-f3d5-4502-8425-19bed7c2d135",[1054],[1308],{"id":1309,"sortIndex":23,"affiliation":1310,"properties":22},"22b6c264-6ab8-4d35-9953-7aa4f1167858",{"id":1309,"createTime":22,"updateTime":22,"relativeEntities":1311,"slug":22,"properties":1312,"entityType":22,"verifyStatus":22,"verifyTime":22,"verifyNote":22,"languages":22,"translateLanguages":22,"viewCount":22,"url":22,"parentIds":1315,"statistic":22},[],{"title":1313},{"VI":1314},"Håvundvegen125, Skien, Norway",[],{"title":1317},{"VI":1318},"Inger Cecilie 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of the occupational medical examination program in South Korea",{"VOID":1410},"10.1007\u002Fs004200050394",{"EN":1412}," The South Korean government carried out reforms in the occupational medical examination program over a period of 2 years from 1997 to 1998 in a response to the discontent of workers, who had complained that occupational medical examinations were merely ritualistic and unproductive. The purposes of this manuscript are to describe the reason for the remodeling, with a historical review of the existing occupational medical examination program in South Korea, and to discuss the main issues involved in remodeling the program. The existing occupational medical examination program in South Korea was reviewed and criticized. The basic philosophy and the main issues in remodeling South Korea's occupational medical examination program were also discussed. In conclusion, the occupational medical examination program should not be conducted in a uniform manner according to legal regulations, but should be a part of overall occupational health services. Individual workplaces should be given the autonomy to perform medical examinations according to the characteristics of the workplace. An enabling approach based on the participation of labor and management should be taken into consideration.","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs004200050394",[1415,1430,1443],{"id":1416,"sortIndex":23,"researcher":22,"roles":1417,"affiliations":1418,"properties":1427},"a9a1822d-5e4c-4240-9d13-7b879f9529b7",[1054],[1419],{"id":1420,"sortIndex":23,"affiliation":1421,"properties":22},"a0235baa-beae-49f0-8040-6e1615f398dc",{"id":1420,"createTime":22,"updateTime":22,"relativeEntities":1422,"slug":22,"properties":1423,"entityType":22,"verifyStatus":22,"verifyTime":22,"verifyNote":22,"languages":22,"translateLanguages":22,"viewCount":22,"url":22,"parentIds":1426,"statistic":22},[],{"title":1424},{"VI":1425},"Industrial Safety and Health Research Institute, Korea Industrial Safety Corporation (KISCO), 34-6 Kusan-dong, Bepyeong-ku, Inchon 403-711, South Korea, , KR",[],{"title":1428},{"VI":1429},"J. 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previously described experimental model for studying the effects on the central nervous system of rabbits, specifically the vestibular apparatus, has been applied to methylchloroform. To achieve a steady concentration the solvent was infused as a lipid emulsion. The blood and cerebrospinal fluid kinetics have been studied. The arterial blood level seems to be closely correlated to the concentration in the central nervous tissue. Vestibular function has been studied by recording the involuntary eye movements — nystagmus — which are elicited via central vestibulo-oculomotor connections. At blood levels of methylchloroform above 75 ppm a so called “positional nystagmus”, indicated vestibular disturbances, is demonstrated. The relationship between the present findings in rabbits and the reaction and blood concentrations in people exposed to industrial solvents, are discussed.",{"EN":1517},"Exposure of rabbits to methylchloroform. Vestibular disturbances correlated to blood and cerebrospinal fluid levels",{"VOID":1519},"American Conference of Governmental Industrial Hygienists. Threshold limit values for chemical substances and physical agents in the workroom environment with intended changes for 1973\nAschan, G.: Different types of alcohol nystagmus. Acta Otolaryngol. Suppl 140, 69–78 (1958)\nAschan, G.: Studies on the ascending vestibuloocular reflex arc. Wenner-Gren Symposium No. 15, Oxford, New York: Pergamon Press (1970)\nAschan, G., Bergstedt, M.: Balanssinnesfunktion vid alkoholintoxikation. Ann. Acad. Regiae Scient, Upsaliensis, 1, 36–52 (1957)\nAschan, G., Bergstedt, M.: Positional alcoholic nystagmus (PAN) in man following rapeated alcohol doses. Acta Otolaryngol. Suppl. 330, 15–29 (1975)\nAschan, G., Bergstedt, M., Goldberg, L., Laurell, L.: Positional nystagmus in man during and after alcohol intoxication. Quart. J. Stud. Alcohol 17, 381–405 (1956)\nAschan, G., Bergstedt, M., Goldberg, L.: Positional alcohol nystagmus in patients with unilateral and bilateral labyrinthine destructions. Confin. neurol. 24, 80–102 (1964a)\nAschan, G., Ekvall, L., Grant, G.: Nystagmus following stimulation in the central vestibular pathways using permanently implanted electrodes. Acta Otolaryngol. Suppl. 192, 63–77 (1964)\nAschan, G., Bunnfors, I., Hydên, D., Larsby, B., Ödkvist, L.M., Tham, R.: Xylene exposure. Electronystagmographic and gaschromatographic studies in rabbits. Acta Otolaryngol. 84, 370–376 (1977)\nÅstrand, I.: Uptake of solvents in the blood and tissues of man. A review. Scand. j. work environ. & health 1, 199–218 (1975)\nÅstrand, I., Kilbom, A., Wahlberg, I., Övrum, P.: Methylchloroform exposure. I. Concentration in alveolar air and blood at rest and during exposure. Work-environs health 10, 68–91 (1973)\nAxelsson, O., Hane, M., Hogstedt, C.: Neuropsychiatric ill-health in workers exposed to solvents — a case control study. Sv. Läkartidningen 73, 322–325 (1976)\nBrodie, B.: Kinetics of absorption, distribution, excretion and metabolism of drugs. In Animal and clinical pharmacologic techniques in drug evaluation. Ed. Nodine, J. and Siegler, P. Vol. I, p. 69–88, Year Bk. 1967\nDeutsche Forschungsgemeinschaft: MSK-Went; 1, 1, 1-Trichloroäthan; Weinheim: Verlag Chemie 1973\nGamberale, F., Hultengren, M.: Toluene exposure. II. Phychophysiological function. Workenviron.-health 9, 131–139 (1972)\nGamberale, G., Hultengren, M. Methylchloroform exposure. I. Psychophysiological functions. Work-environ.-health 10, 82–92 (1973)\nGoldstein, A., Aranow, L., Kalman, S.: Principles of drug action. The basis of pharmacology. New York, London: John Wiley 1974\nJapanese Association of Industrial Health: Recommended threshold limit values for 1973. Jap. J. industrial Health (Sangyo Igako) 15, 280–286 (1973)\nLarsby, B., Ödkvist, L.M., Hydén, D., Liedrgren, S.R.C.: Disturbances of the vestibular system by toxic agents. Acta Phys. Scand. Suppl. 440, (1976)\nPapper, E.M., Kitz, R.J.: Uptake and distribution of anasthetic agents. New York, Toronto, London: McGraw-Hill Book 1963\nReport of the Swedish National Board of Occupational Safety and Health: Threshold limits in the workroom environment 1974\nSalvini, M., Binaschi, S., Riva, M.: Evaluation of the psychophysiological functions in humans expsosed to the ‘Threshold Limit Value’ of 1, 1, 1-trichloroethane. Brit. J. industr. Med 28, 286–292 (1971)\nSeppäläinen, A.M.: Application of neurophysiological methods in occupational medicine. Scand. j. work environ. & health 1, 1–14 (1975)\nStewart, R.D., Guy, H.H., Schaffer, A.W., Erley, D.S., Rowe, V.K.: Experimental human exposure to methylchloroform vapor. Arch. environm. hlth 19, 467–472 (1969)\nStewart, R.D., Andrews, J.T.: Acute intoxication with methylchloroform. JAMA (March 14) 195, 120–122 (1966)\nTorkelson, T.R., Qyen, F., McCollister, D.D., Rowe, V.K.: Toxicity of 1, 1, 1-trichloroethane as determined on laboratory animals an human subjects. Amer. industr. hyg. Ass. 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surveillance in the work environment involves continuous biological monitoring and medical screening, with the purpose of primary and secondary prophylaxis of work-related diseases. Is this screening activity governed by a rationale based on knowledge of dangerous exposure and the availability of valid tests? In the USA, where health surveillance programmes are used extensively, a study has found screening activity to be associated more with plant size than wick relevant exposure. This study was done to elucidate the character and extent of use of health surveillance in the work environment in the EC countries with the aid of a questionnaire survey. The chief medical officers of the National Labour Inspectorates supplied information on substances covered by health surveillance programme in the EC member states, together with the legislative status and numbers of exposed workers. Belgium, France, Italy and the former Federal Republic of Germany made extensive use of health surveillance programmes in cases of known exposure to metals, organic solvents, carcinogenic and genotoxic substances, mineral dust, ionizing radiation, and biological agents. Denmark and Holland ran national programmes only for substances covered by EC directives, while England, Ireland, Spain, and Portugal comprised an intermediate user group. The result suggest that the use of health surveillance is related more to the national choice of standard regulatory instruments than to relevant exposure.",{"EN":1678},"Biological monitoring and medical screening at the workplace in the EC countries",{"VOID":1680},"Aitio A, Riihimaki V, Vainio H (eds) (1984) Biological monitoring and surveillance of workers exposed to chemicals, Hemisphere, Washington\nAngerer J, Schaller KH (eds) (1988) Analyses of hazardous substances in biological materials. Methods for biological monitoring, vol 2. DFG Deutsche Forschungsgemeinschaft. VCH, Weinheim\nAnonymous (1988) Berufsgenossenschaftliche Grundsätze für arbeitsmedizinische Vorsorgeuntersuchungen. Hautpverband der gewerblichen Berufsgenossenschafen e. V. Gentner, Stuttgart\nBerlin A, Yodaiken RE, Henman BA (eds) (1984) Assessment of toxic agents at the work place. Martinus Nejhoff, Boston\nBernard A, Lauwerys R (1986) Present status and trends in biological monitoring of exposure to industrial chemicals. J Occup Med 28:558–562\nHalperin WE, Ratcliffe J, Frazier TM, Wilson L, Becker SP, Schulte PA (1986) Medical screening in the workplace: proposed principles. J Occup Med 28:547–552\nLutsky I, Kalbfleish JH, Fink JN (1983) Occupational allergy to laboratory animals: employer practices. J Occup Med 25:372–376\nMcNeil B, Eddy DM (1982) The costs and effects of screening for cancer among asbestos-exposed workers. J Chron Dis 35:351–358\nMillar JD (1986) Screening and monitoring: tools for prevention. J Occup Med 28:544–547\nRasmussen K, Lunde-Jensen P, Svane O (1989) Biological monitoring and medical screening in the workplace. The Commission of the European Communities, Directorate-General for Employment, Social Affairs and Education, Luxembourg\nRathcliffe JM, Halperin WE, Frazier TM, Sundin DS, Delaney L, Horning RW (1986) The prevalence of screening in industry: report from the National Institute of Occupational Safety and Health, National Occupational Hazard Survey. J Occup Med 28:906–912\nZielhuis RL, Henderson PT (1986) Definitions of monitoring activities and their relevance for the practice of occupational health. 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1896 the lead smelting plant in MeŽa valley, Slovenia, Yugoslavia, is contaminating the environment with lead aerosols. From 1968 a broad ecological and epidemiological study on environmental contamination and human exposure is developed. Determination of lead in the soil represent a part of these complex investigations. On 33 sampling spots along the valley the soil and plant samples were taken every year in July and October. The results of the total lead content of the soil for 1968 and 1969 are presented, together with the data about quantitative distribution in the valley. However, investigations on adsorption coefficient (soil: plant) revealed that the total lead content does not represent a reliable parameter for such calculations. Therefore authors applied for the first time determination of lead in the acetate: lactate extract of the soil. This parameter is showing in some cases a better correlation between lead in soil and underground parts of plants. It seems that determination of AL-soluble lead from the soil represent a step forward (but not definite) in the determination of absorbable part of lead. The distribution of lead aerosols on the earth surface and factors influencing it are discussed.",{"EN":1787},"Lead contamination of environment in Meža valley",{"VOID":1789},"Djurić, D., Kerin, Ž.: Some considerations on lead content in soil and plants. Symposium on Human Ecology, Prague, 13 October 1970 (to be published).\nDjurić, D., Kerin, Ž., Graovac-Leposavić, Lj., Novak, Lj., Kop, M.: Environmental contamination by lead from a mine and smelter. A preliminary report. Arch. environm. Hlth 23, 275 (1971).\nJaworowski, Z.: Stable and radioactive lead in environment and human body. Warsaw: Nuclear Information Center Publication 1967.\nKerin, Ž.: Bestimmung von Mikromengen Blei in pflanzlichem Material. Mikrochmioa Acta 5, 927 (1968).\nMonography: 300 Let Mežiški Rudniki. Mežica 1965.\nRiehm, A.: Die Ammoniumlaktate-EssigsÄure-Methode zur Bestimmung des Kaliumversorgungsgrades von Boden. Agrochimica 1 (1958).\nWentzel, K. P.: Untersuchungen über die von einer Bleihütte ausgehenden Immissionen. 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We conducted a cross-sectional study to evaluate the lung function and respiratory symptoms of Hong Kong bus and tram drivers exposed to air pollutants. Methods: Demographic information, vital signs, pulmonary function, respiratory symptoms and blood lead levels in 358 male drivers of air-conditioned buses (ACB) were compared with 129 male drivers of non-air-conditioned buses and trams (NACB). Particulate matter (PM10), carbon dioxide (CO2) and carbon monoxide (CO) levels were measured in 16 air-conditioned and 15 non-air-conditioned trams along the same route. Results: Forced vital capacity, forced expiratory volume in 1 s and maximal voluntary ventilation were lower but blood lead levels were higher in the NACB drivers compared with ACB drivers. More NACB drivers compared to ACB drivers reported frequent productive cough, dry cough, as well as sore throat. The measured lung function parameters in the NACB drivers were lower than a cohort of personnel working in an academic environment. The work-year duration was longer and scheduled days off per month were shorter for NACB (13.4±8.8 years and 4.3±1.3 days) compared to ACB drivers (11.5±9 years and 5.4±0.8 days), respectively (P\u003C0.001). The PM10 and CO2 levels were higher in ACB (265±83 μg\u002Fm3 and 2,114±69.6 ppm) compared to non-air-conditioned trams (161±103 μg\u002Fm3 and 500 ppm, respectively) (P\u003C0.005). Conclusion: We hypothesise that prolonged exposure to air pollutants adversely affects lung function in our NACB drivers but air recirculation could result in higher blood lead levels in ACB drivers.",{"EN":1978},"Respiratory health of bus drivers in Hong Kong",{"VOID":1980},"American Thoracic Society (1995) Standardization of spirometry. 1994 update. Am J Respir Crit Care Med 152:1107–1136\nASHRAE (2005). American Society of Heating, Refrigerating and Air-conditioning Engineers. http:\u002F\u002Fwww.ashrae.org (last accessed August 2005)\nBenjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 57:289–300\nChao CY, Wong KK (2002) Residential indoor PM10 and PM2.5 in Hong Kong and the elemental composition. Atmos Environ 36:265–277\nD’Amato G (2002) Environmental urban factors (air pollution and allergens) and the rising trends in allergic respiratory diseases. Allergy 57(Suppl 72):30–33\nEPA (2005) Environmental Protection Agency, USA. http:\u002F\u002Fwww.airmonitoring.utah.gov\u002FPm10.htm (accessed August 2005)\nFinkelstein MM, Jerrett M, Sears MR (2004) Traffic air pollution and mortality rate advancement periods. Am J Epidemiol 160:173–177\nGuo L, Jin Y (2003) Outdoor air pollution and its health impacts. J Hyg Res 32:284–286\nHackley B, Katz-Jacobson A (2003) Lead poisoning in pregnancy: a case study with implications for midwives. J Midwifery Womens Health 48:30–38\nHKEPD (2003) Air quality in Hong Kong. Air Service Group, Environmental Protection Department, The Government of the Hong Kong Special Administrative Region. http:\u002F\u002Fwww.epd.gov.hk\u002Fepd\u002Fenglish\u002Fenvironmentinhk\u002Fair\u002Fair_quality\u002Faq_annualrpt.html (last accessed August 2005)\nHKTD (2005) Transport Department, Hong Kong. http:\u002F\u002Fwww.td.gov.hk\u002Ftransport_in_hong_kong\u002Ftransport_figures\u002Fmonthly_traffic_and_transport_digest\u002Findex.htm (last accessed September 2005)\nKa MW, Tanner PA (2001) Monitoring long-term variation of aerosol composition: a dual particle-size approach applied to Hong Kong. Environ Monit Assess 79:275–286\nKMB (2005) The Kowloon Motor Bus Co. http:\u002F\u002Fwww.kmb.hk\u002F (last accessed August 2005)\nPolosa R (2001) The interaction between particulate air pollution and allergens in enhancing allergic and airway responses. Curr Allergy Asthma Rep 1:102–107\nProPECC PN (2003) Practice Note for Managing Air Quality in Air-conditioned Public Transport Facilities. Environmental Protection Department, November 2003\nShi S, Chan Z, Liang Y (1995) Effect of lead on neurobehaviour and neurochemistry in rats (Chinese). Zhong Hua Yu Fang Yi Xue Za Zhi 29:80–82\nStaessen J (1995) Low-level lead exposure, renal function and blood pressure. Verhandelinger Koninklijke Academie voor Geneeskunde van Belgie 57:527–574\nStaudinger KC, Roth VS (1998) Occupational lead poisoning. Am Fam Physician 57:719–726\nTamura K, Jinsart W, Yano E, Karita K, Boudoung D (2003) Particulate air pollution and chronic respiratory symptoms among traffic policemen in Bangkok. Arch Environ Health 58:201–207\nTsaih SW, Korrick S, Schwartz J, Amarashiriwardena C, Aro A, Sparrow D, Hu H (2004) Lead, diabetes, hypertension, and renal function: the Normative Aging Study. Environ Health Perspect 112:1178–1182\nUlfvarson U, Alexandersson R, Aringer L, Svensson E, Hedenstierna G, Hogstedt C, Holmberg B, Rosen G, Sorsa M (1987) Effects of exposure to vehicle exhaust on health. Scand J Work Environ Health 13:505–512\nWorld Health Organization Regional Office for Europe (WHO) (1987) Air quality guidelines for Europe 22. WHO Regional Publication, Copenhagen, pp 242–261\nYee HY, Nelson JD, Jackson B (1994) Measurement of lead in blood by graphite furnace atomic absorption spectrometry. J Anal Toxicol 18:415–418",{"VOID":1982},"10.1007\u002Fs00420-005-0061-8","https:\u002F\u002Flink.springer.com\u002Farticle\u002F10.1007\u002Fs00420-005-0061-8",[1985,2000,2013],{"id":1986,"sortIndex":23,"researcher":22,"roles":1987,"affiliations":1988,"properties":1997},"09ecab13-4624-4f3d-8ad7-81be8bc330bb",[1054],[1989],{"id":1990,"sortIndex":23,"affiliation":1991,"properties":22},"b4eb7bf6-5e75-4249-94ce-32ab6425efcb",{"id":1990,"createTime":22,"updateTime":22,"relativeEntities":1992,"slug":22,"properties":1993,"entityType":22,"verifyStatus":22,"verifyTime":22,"verifyNote":22,"languages":22,"translateLanguages":22,"viewCount":22,"url":22,"parentIds":1996,"statistic":22},[],{"title":1994},{"VI":1995},"Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China",[],{"title":1998},{"VI":1999},"A. Y. M. 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aim of the study was to characterize the nature of the formaldehyde-induced nasal response consisting in symptoms of rhinitis and changes in nasal lavage fluid. Eleven healthy subjects and nine patients with specific skin sensitization were provoked in a toxicological chamber with formaldehyde at a dose of 0.5 mg\u002Fm3 over 2 h. Nasal lavage was performed prior to and immediately after provocation and 4 and 18 h later. Provocation with formaldehyde caused transient symptoms of rhinitis and prolonged changes in nasal washings. There were increases in the number and proportion of eosinophils and elevated albumin and total protein levels in nasal lavage fluid 4 and 18 h after provocation. No difference in the nasal response to formaldehyde was found between patients with skin sensitization and healthy subjects. These data confirm the irritative effects of formaldehyde and are also suggestive of nonspecific proinflammatory properties when formaldehyde is inhaled at a low (0.5 mg\u002Fm3) dose.",{"EN":2087},"Changes in nasal lavage fluid due to formaldehyde inhalation",{"VOID":2089},"Bardana JB, Montanaro A (1991) Formaldehyde: an analysis of its respiratory, cutaneous and immunologic effects. Ann Allergy 66:441–446\nBarnes PJ (1987) Neuropeptides in human airways: function and clinical implications. Am Rev Respir Dis 136:S16-S26\nBascom R, Pipkorn U, Lichtenstein LM, Naclerio RM (1988) The influx of inflammatory cells into nasal washings during the late response to antigen challenge; effect of systemic corticosteroids. Am Rev Respir Dis 138:406–412\nBrofeldt S, Mygind N, Sorensen CH, Marriot C (1986) Biochemical analysis of nasal secretions induced by methacholine, histamine and allergen provocations. Am Rev Respir Dis 133:1138–1142\nCastells M, Schwartz LB (1988) Tryptase levels in nasal-lavage fluid as an indicator of the immediate allergic response. J Allergy Clin Immunol 82:348–355\nChang JCF, Gross EA, Swenberg JA, et al. (1983) Nasal cavity deposition, histopathology and cell proliferation after single or repeated formaldehyde exposures in B6C3F mice and F344 rats. Toxicol Appl Pharmacol 68:161–171\nDrury RA (1967) Carleton's histological technique. Oxford University Press, New York p 309\nEdling C, Herlquist H, Odkvist L (1988) Occupational exposure to formaldehyde and histopathological changes in the nasal mucosa. Br J Ind Med 45:761–765\nGrammer LC, Harris KE, Shaughnessy MA, et al. (1990) Clinical and immunologic evaluation of 37 workers exposed to gaseous formaldehyde. J Allergy Clin Immunol 86:177–181\nGreiff L, Pipkorn U, Alkner U, Persson CGA (1990) The “nasal pool” device applies controlled concentrations of solutes on human nasal airway mucosa and samples its surface exudation\u002Fsecretions. Clin Exp Allergy 86:599–605\nHansel FK (1954) The cytology of secretions in allergy. In: Hansel FK (ed) Clinical allergy. CV Mosby, St. Louis, pp 408–419\nHewndrick DJ, Rando RJ, Lane DJ, et al. (1982) Formaldehyde asthma challenge exposure levels and late reactions after 5 years. J Occup Med 24:897\nKalendarian R, Raju L, Roth W, Schwartz LB (1988) Elevated histamine and tryptase levels in smoker's bronchoalveolar lavage fluid. Do lung mast cells contribute to smoker's emphysema? Chest 94:119–123\nLowry OL, Rosebrough MJ, Farr AL, Randall RJ (1951) Protein measurement with the folin-phenol reagent. J Biol Chem 193:265–275\nMaibach HI (1983) Formaldehyde: effects on animal and human skin. In: Gibson JE (ed) (1983) Formaldehyde toxicity. Hemisphere, pp 163–174\nMattson DE (1981) Statistics. C.V. Mosby, St. Louis.\nRaphael GD, Meredith SDF, Baraniuk JN, Druce HM, Banks SM, Kaliner MA (1989) Pathophysiology of rhinitis. II. Assessment of the sources of protein in histamine-induced nasal secretions. Am Rev Respir Dis 139:791–800\nRaphael GD, Igarashi Y White MV, Kaliner MA (1991) The pathophysiology of rhinitis. Sources of protein in allergen induced nasal secretions. J Allergy Clin Immunol 88:33–42\nWalker KB, Serwonska MJ, Valvone FJ et al. (1988) Distinctive patterns of release of neuroendocrine peptides after nasal challenge of allergic subjects with ryegrass antigen. J Clin Immunol 8:108–113\nZeiger RS, Yurdin DL, Colten HR (1976) Histamine metabolism, II. Cellular and subcellular of localization in the catabolic enzymes, histaminase and histamine methyl transferase in human leukocytes. 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