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Journal of Medicine and Pharmacy","Tạp chí Y Dược học Cần Thơ",{"EN":487,"VI":488},"\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">04\u002F10\u002F2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 \u002FGP-BTTTT)\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">07\u002F16\u002F2015 Can Tho journal of medicine and pharmacy is internationally recognized: ISSN 2354-1210\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The content published\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The journal is divided into 3 categories:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Scientific research article: are valuable scientific works, which have been researched and accepted.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Overview of medicine, biology and pharmacy: serving the objective of continuing training in the fields of medicine, biology and pharmacy; to systematize classical and modern knowledge.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Update information on new knowledge about medicine, biology, pharmacy in the country and in the world.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Scope\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Publication and introduction of scientific research in the fields:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Medicine (internal medicine, surgery, pediatrics, obstetrics and gynecology, odonto-stomatology, laboratory, oncology, traditional medicine, nursing).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Biology (genetics, biotechnology).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">+ Pharmacology (pharmaceutics, drug quality analysis-control, synthetic pharmaceutical chemistry, biochemistry, pharmacognosy, botany, clinical pharmacy).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- To enhance the quality of undergraduate, postgraduate education, scientifically researching and meet the necessary treatment in hospital.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Introducing the updated domestic and oversea information about science technology to promote scientific research and exchanging technology in local, other universities.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">- Exchanging pharmaceutical and medical information for social health developing in the Mekong Delta and Vietnam.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">The object\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Postgraduate students, student of Can Tho University of Medicine and Pharmacy, scientists from schools, research institutes, hospitals, health centers, pharmaceutical companies of the Mekong Delta; other provinces and regions in Vietnam and other country.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Address\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Headquarters of Can Tho Journal of Medicine and Pharmacy, located Scientific Research and International Cooperation Office: 179 Nguyen Van Cu Street, An Khanh Ward, Ninh Kieu District, Can Tho City, Vietnam.\u003C\u002Fspan>\u003C\u002Fp>","\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Ngày 16\u002F7\u002F2015, Tạp chí Y Dược học Cần Thơ được cấp chỉ số quốc tế: ISSN 2354-1210.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 4\u002F2016, Tạp chí đã được Hội đồng Giáo sư ngành Y đưa vào danh sách các tạp chí khoa học Y học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Năm 2020 Tạp chí Y Dược học Cần Thơ đã được phê duyệt vào danh mục của các Hội đồng Giáo sư ngành Dược học được tính điểm công trình 0-0,5 điểm cho một bài báo đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ ra 12 số\u002Fnăm, 180-200 trang\u002Fsố.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Từ tháng 12\u002F2022 Tạp chí Y Dược học Cần Thơ là thành viên của hệ thống Crossref và từ tháng 01\u002F2023 tạp chí thực hiện bình duyệt online kín 2 chiều nhằm tăng tính minh bạch, tin cậy của các công trình nghiên cứu khoa học và đảm bảo tốt nhất chất lượng khoa học của bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ, mục đích và phạm vi của tạp chí\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tôn chỉ và mục đích hoạt động của tạp chí: xuất bản nhằm mục đích phổ biến kết quả từ các đề tài nghiên cứu khoa học; giao lưu trao đổi khoa học, chia sẻ kinh nghiệm, học tập, đồng thời cập nhật thông tin khoa học mới trong các lĩnh vực y, sinh, dược học trong và ngoài nước.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phạm vi của tạp chí: Tạp chí xuất bản được chia thành 3 chuyên mục: (i) Bài báo nghiên cứu khoa học là kết quả công trình nghiên cứu khoa học có giá trị đã được triển khai nghiên cứu, (ii) Bài tổng quan y, sinh, dược học: phục vụ mục tiêu đào tạo liên tục trong lĩnh vực y, sinh, dược học; nhằm hệ thống hóa những kiến thức kinh điển và hiện đại; (iii) Thông tin cập nhật kiến thức mới về y, sinh, dược học trong nước và trên thế giới.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Chính sách truy cập mở\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ áp dụng chính sách truy cập mở đối với các bài báo đã xuất bản đến với độc giả, nhằm mở rộng cơ hội tiếp cận các kết quả nghiên cứu chất lượng cao và tăng cường trao đổi kiến thức. Tạp chí đăng tải trực tuyến (miễn phí) toàn văn các bài báo được công bố trên website của Tạp chí (https:\u002F\u002Ftapchi.ctump.edu.vn).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đạo đức xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ cam kết tuân thủ đạo đức xuất bản phù hợp với các hướng dẫn và tiêu chuẩn của the Committee on Publication Ethics (COPE), tuân thủ các nguyên tắc của COPE’s Core Practices, Best Practices Guidelines for Journal Editors và Guidelines on Good Publication Practices.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Bản thảo bài báo chỉ được chấp nhận khi được tác giả chịu trách nhiệm chính cam kết các nội dung sau: Các nội dung của bản thảo chưa được đăng tải toàn bộ hoặc một phần ở các tạp chí khác; Tất cả các tác giả đều có đóng góp một cách đáng kể vào quá trình nghiên cứu hoặc chuẩn bị bản thảo và cùng chịu trách nhiệm về các nội dung của bản thảo; Tuân thủ các biện pháp đảm bảo đạo đức nghiên cứu (ví dụ thỏa thuận đồng ý tham gia nghiên cứu).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Cam kết bảo mật\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí cam kết thực hiện và tuân thủ các quy định của luật và các văn bản hướng dẫn liên quan đến bảo mật thông tin cá nhân trên không gian mạng. Các thông tin mà người dùng (tác giả, độc giả, biên tập viên, người phản biện) nhập vào các biểu mẫu trên Hệ thống Quản lý xuất bản trực tuyến của tạp chí chỉ được sử dụng vào các mục đích đã được tuyên bố rõ ràng và sẽ không được cung cấp cho bất kỳ bên thứ ba nào khác, hay dùng vào bất kỳ mục đích nào khác.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Phí gửi bài\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng bài: 1.000.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Lệ phí gửi đăng nhanh: 1.500.000đ\u002Fbài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với tác giả là cán bộ viên chức thuộc Trường Đại học Y Dược Cần Thơ thì được hỗ trợ 50% lệ phí gửi đăng bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Đối với sinh viên thực hiện đề tài nghiên cứu khoa học cấp trường được hỗ trợ 100% lệ phí đăng bài ( Tác giả gửi đính kèm “ Quyết định về việc giao tổ chức thực hiện đề tài nghiên cứu khoa học cấp Trường của sinh viên”).\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Hình thức nộp lệ phí:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Tiền mặt:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Nộp trực tiếp tại Phòng Tài chính - Kế toán, Trường Đại học Y Dược Cần Thơ, số 179 Nguyễn Văn Cừ, P. An Khánh, Q. Ninh Kiều, thành phố Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Chuyển khoản:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tên Tài khoản: Trường ĐHYD Cần Thơ, Số TK: 0111000115668, tại ngân hàng Vietcombank chi nhánh Cần Thơ.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Thời gian: Áp dụng từ ngày 01\u002F02\u002F2023.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">* Phí gửi bài không được hoàn trả khi bài viết bị từ chối hoặc tác giả xin rút bài viết.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Quy trình phản biện bài báo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tạp chí Y Dược học Cần Thơ thực hiện quy trình phản biện kín hai chiều nghiêm ngặt. Danh tính của những người phản biện không được tiết lộ cho các tác giả và ngược lại. Quy trình thẩm định bài báo đăng gồm các bước sau:\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tiếp nhận bản thảo\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Tác giả liên hệ gửi bản thảo đến Tạp chí qua hệ thống trực tuyến tại website: https:\u002F\u002Ftapchi.ctump.edu.vn. Hướng dẫn về cách đăng ký, gửi bài và chuẩn bị bản thảo được cung cấp trên website của Tạp chí.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sàng lọc sơ bộ\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Sau khi Tòa soạn nhận được bài báo của tác giả, Ban Thư ký sẽ tiến hành kiểm tra sơ bộ bài báo (các yêu cầu về nội dung và hình thức). Những bài báo không đúng quy cách hoặc có nội dung không phù hợp hoặc vi phạm bản quyền sẽ bị từ chối (Ban Thư ký thông báo phản hồi đến tác giả trong vòng 1 tuần). Những bài báo đủ điều kiện, được Ban Thư ký tòa soạn chuyển đến Ban Biên tập có cùng chuyên môn với nội dung bài báo để đề xuất người phản biện. Thời gian kể từ khi Ban Biên tập nhận bài báo đến khi đề xuất người phản biện bài báo chậm nhất là 5 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Vòng phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký gửi bài và yêu cầu phản biện đến 02 phản biện độc lập.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Các phản biện gởi nhận xét cho Ban Thư ký. Thời gian từ khi gửi bài cho phản biện đến khi nhận ý kiến của phản biện tối đa là 20 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xử ký kết quả phản biện\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Nếu ý kiến đồng ý cho đăng và không cần chỉnh sửa, Ban Thư ký tiếp tục đăng bài theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Nếu ý kiến đồng ý đăng và cần chỉnh sửa, Ban Thư ký sẽ thông tin đến tác giả chỉnh sửa theo yêu cầu của người phản biện. Thời gian chỉnh sửa và gửi lại kéo dài không quá 2 tuần, từ khi tác giả bài báo nhận được thông tin (Quá trình này có thể lặp lại tối đa 2 lần\u002F1 bài báo). Khi có sự thống nhất, đồng ý của người phản biện; bài báo được tiếp tục đăng theo qui trình.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Những bài báo có chất lượng không đạt yêu cầu, cả 2 phản biện không đồng ý cho đăng sẽ bị Tòa soạn từ chối đăng.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">Xuất bản\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">1. Ban Thư ký tổng hợp các bản thảo đã được tác giả hoàn thiện sau thẩm định trình Ban Biên tập xem xét, Tổng Biên tập phê duyệt, quyết định bài đăng theo các tiêu chí: sự phù hợp nội dung với tôn chỉ và mục đích, thể loại bài viết (ưu tiên các bài có bài có nghiên cứu chuyên sâu, hàm lượng khoa học cao), đóng góp mới bài báo, bài báo được ưu tiên đăng trong số gần nhất của Tạp chí theo thứ tự: tính thời sự, chất lượng bài báo và thời gian gửi bài.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">2. Ban Biên tập và Ban Thư ký biên tập bản thảo, chế bản, đọc rà soát lỗi. Thời gian hoàn thành từ 10-15 ngày.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">3. Ban Thư ký có trách nhiệm thông báo cho tác giả bài báo (bằng e-mail) về tình hình phê duyệt bài báo, thời gian, số kỳ, tập xuất bản bài báo theo qui định.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(0, 0, 0);\">4. Danh sách bài báo theo số Tạp chí được in ấn và phát hành trong năm định kỳ được công bố chính thức trên website: https:\u002F\u002Ftapchi.ctump.edu.vn\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>",{"VOID":490},"wcQ1uqwAAAAJ","2023-05-30T08:17:21.868+00:00",[],[494],{"id":495,"createTime":28,"updateTime":28,"relativeEntities":496,"slug":28,"properties":497,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":507,"parentIds":508,"statistic":28},"6413896b-eca9-442b-a73f-182a58a0ce40",[],{"title":498,"address":501,"country":504,"abbreviation":505},{"EN":499,"VI":500},"Can Tho University of Medicine and Pharmacy","Trường Đại học Y Dược Cần Thơ",{"EN":502,"VI":503},"No 179, Nguyen Van Cu street, An Khanh ward, Ninh Kieu district, Can Tho city, Vietnam","Số 179, đường Nguyễn Văn Cừ, phường An Khánh, quận Ninh Kiều, thành phố Cần Thơ, Việt Nam",{"VOID":15},{"VOID":506},"ctump","http:\u002F\u002Fwww.ctump.edu.vn\u002F",[],[],"https:\u002F\u002Ftapchi.ctump.edu.vn\u002Findex.php\u002Fctump",{"impactFactor":32,"impactFactorByYear":512,"i10Index":32,"i10IndexLast5Year":32,"totalPublication":514,"totalPublicationByYear":515,"totalCitation":520,"totalCitationByYear":521,"totalCitationPerPublication":108,"totalCitationPerPublicationByYear":523,"hindexLast5Year":45,"hindex":45},{"2022":513,"2023":111,"2024":106},0.01,1556,{"2020":47,"2021":516,"2022":517,"2023":518,"2024":519,"2025":122},57,306,801,358,161,{"2021":146,"2022":280,"2023":522},99,{"2021":524,"2022":318,"2023":104},0.23,{"impactFactor":28,"impactFactorByYear":28,"i10Index":123,"i10IndexLast5Year":123,"totalPublication":526,"totalPublicationByYear":527,"totalCitation":526,"totalCitationByYear":528,"totalCitationPerPublication":40,"totalCitationPerPublicationByYear":531,"hindexLast5Year":49,"hindex":49},476,{"0":205,"2019":123,"2021":139,"2022":459,"2023":451,"2024":357,"2025":49,"2026":48},{"2021":42,"2022":123,"2023":161,"2024":529,"2025":360,"2026":530},136,83,{"2021":105,"2022":513,"2023":532,"2024":127,"2025":533,"2026":534},0.62,25.43,13.83,{"id":536,"createTime":537,"updateTime":382,"relativeEntities":538,"slug":539,"properties":540,"entityType":25,"verifyStatus":26,"verifyTime":28,"verifyNote":28,"languages":552,"translateLanguages":28,"viewCount":133,"subjectFields":553,"manageAffiliations":554,"indexDatabases":555,"url":556,"thumbnailPath":557,"statistic":558,"gsStatistic":594,"type":55,"analyzePriority":28},"6984a56a-db70-403b-9cc4-4013e1ceaffa","2023-05-09T06:47:40.346+00:00",[],"T%E1%BA%A1p%20ch%C3%AD%20Nghi%C3%AAn%20c%E1%BB%A9u%20n%C6%B0%E1%BB%9Bc%20ngo%C3%A0i",{"country":541,"issn":542,"title":544,"introduce":547,"gsId":550},{"VOID":15},{"VOID":543},"25252445",{"EN":545,"VI":546},"VNU Journal of Foreign Studies","Tạp chí Nghiên cứu nước ngoài",{"EN":548,"VI":549},"{\"ops\":[{\"insert\":\"\\n\\nThe \\n\"},{\"attributes\":{\"italic\":true},\"insert\":\"VNU Journal of Science\"},{\"insert\":\"\\n was established in 1985 for the publication of national and international research papers in all fields of natural sciences and technology, social sciences and humanities. 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Science Citation Index Expanded",{"EN":921,"VI":922},"SCIE database","Cơ sở dữ liệu SCIE","scie",[925,813],"SCIE","https:\u002F\u002Fmjl.clarivate.com\u002Fsearch-results?issn=1474-760X",[928,929],"a88c02c1-1408-46e6-b021-2667e298d14d","2d71e6a0-13e8-4e73-be80-f04d8aefea97",{"impactFactor":32,"impactFactorByYear":931,"i10Index":42,"i10IndexLast5Year":40,"totalPublication":933,"totalPublicationByYear":934,"totalCitation":935,"totalCitationByYear":936,"totalCitationPerPublication":698,"totalCitationPerPublicationByYear":937,"hindexLast5Year":42,"hindex":42},{"2018":932,"2019":705,"2022":222,"2023":118},1.78,137,{"2000":49,"2001":49,"2002":47,"2003":45,"2004":48,"2005":45,"2006":45,"2007":48,"2008":46,"2009":46,"2010":48,"2011":42,"2012":45,"2014":40,"2016":123,"2017":49,"2018":42,"2019":46,"2020":46,"2021":205,"2022":45,"2023":48,"2024":134},121,{"2017":451,"2021":126},{"2017":938,"2021":939},15.57,1.2,{"meta":941,"data":943},{"total":942},"4911",[944,1081,1155,1374,1533,1854,2721,2799,2868,3104],{"id":945,"createTime":946,"updateTime":947,"relativeEntities":948,"slug":949,"properties":950,"entityType":959,"verifyStatus":26,"verifyTime":947,"verifyNote":960,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":961,"fullTextUrl":28,"authors":962,"publicationType":1031,"publisherRelationship":1032,"citationCount":28,"citationInfo":28,"publishDate":1077,"publishYear":1078,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":1079,"openAccess":28,"references":28,"isForceReanalyzing":1080},"0007cd82-2cee-47bd-9b09-01af6f8cb140","2024-01-10T17:33:58.645+00:00","2025-01-14T03:36:22.175+00:00",[],"Reference-flow-reducing-reference-bias-using-multiple-population-genomes",{"abstract":951,"title":953,"references":955,"doi":957},{"EN":952},"Most sequencing data analyses start by aligning sequencing reads to a linear reference genome, but failure to account for genetic variation leads to reference bias and confounding of results downstream. Other approaches replace the linear reference with structures like graphs that can include genetic variation, incurring major computational overhead. We propose the reference flow alignment method that uses multiple population reference genomes to improve alignment accuracy and reduce reference bias. Compared to the graph aligner vg, reference flow achieves a similar level of accuracy and bias avoidance but with 14% of the memory footprint and 5.5 times the speed.",{"EN":954},"Reference flow: reducing reference bias using multiple population genomes",{"VOID":956},"Church DM, Schneider VA, Steinberg KM, Schatz MC, Quinlan AR, Chin CS, Kitts PA, Aken B, Marth GT, Hoffman MM, Herrero J, Mendoza ML, Durbin R, Flicek P. Extending reference assembly models. Genome Biol. 2015; 16:13.\nBrandt DY, Aguiar VR, Bitarello BD, Nunes K, Goudet J, Meyer D. Mapping bias overestimates reference allele frequencies at the HLA genes in the 1000 genomes project phase I data. 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Genome Biol. 2018; 19(1):220.\nShukla HG, Bawa PS, Srinivasan S. hg19KIndel: ethnicity normalized human reference genome. BMC Genomics. 2019; 20(1):459.\nDewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, et al. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. 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Read-mapping using personalized diploid reference genome for RNA sequencing data reduced bias for detecting allele-specific expression. In: 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops: 2012. p. 718–24, IEEE.\nChen N-C, Solomon B, Mun T, Iyer S, Langmead B. Reference flow software. 2020. Github https:\u002F\u002Fgithub.com\u002Flangmead-lab\u002Freference_flow.\nChen N-C, Solomon B, Mun T, Iyer S, Langmead B. Reference flow software. 2020. Zenodo https:\u002F\u002Fdoi.org\u002F10.5281\u002Fzenodo.4287778.\nChen N-C, Solomon B, Mun T, Iyer S, Langmead B. Software for reference flow study experiments. 2020. Github https:\u002F\u002Fgithub.com\u002Flangmead-lab\u002Freference_flow-experiments.\nChen N-C, Solomon B, Mun T, Iyer S, Langmead B. Software for reference flow study experiments. 2020. Zenodo https:\u002F\u002Fdoi.org\u002F10.5281\u002Fzenodo.4287729.\nChen N-C, Solomon B, Mun T, Iyer S, Langmead B. Raw data for reference flow experiments. 2020. Zenodo http:\u002F\u002Fdoi.org\u002F10.5281\u002Fzenodo.4287794.\nChen N-C, Solomon B, Mun T, Iyer S, Langmead B. Reference flow VCF for pre-built genomes. 2020. Zenodo http:\u002F\u002Fdoi.org\u002F10.5281\u002Fzenodo.4289428.",{"VOID":958},"10.1186\u002Fs13059-020-02229-3","PUBLICATION","Auto Verify","https:\u002F\u002Fgenomebiology.biomedcentral.com\u002Farticles\u002F10.1186\u002Fs13059-020-02229-3",[963,979,992,1005,1018],{"id":964,"sortIndex":32,"researcher":28,"roles":965,"affiliations":967,"properties":976},"bde26728-2116-40af-a1e1-e1a86d90042f",[966],"AUTHOR",[968],{"id":969,"sortIndex":32,"affiliation":970,"properties":28},"626c1556-39bc-4517-b1ec-6aa290193c7c",{"id":969,"createTime":28,"updateTime":28,"relativeEntities":971,"slug":28,"properties":972,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":975,"statistic":28},[],{"title":973},{"EN":974},"Department of Computer Science; Johns Hopkins University; Baltimore USA",[],{"title":977},{"VI":978},"Nae-Chyun 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cells have three types of RNA polymerases (Pols), Pol I, II, and III. However, the extent to which these polymerases are cross-regulated and the underlying mechanisms remain unclear. We employ genome-wide profiling after acute depletion of Pol I, Pol II, or Pol III to assess cross-regulatory effects between these Pols. We find that these enzymes mainly affect the transcription of their own target genes, while certain genes are transcribed by the other polymerases. Importantly, the most active type of crosstalk is exemplified by the fact that Pol III depletion affects Pol II transcription. Pol II genes with transcription changes upon Pol III depletion are enriched in diverse cellular functions, and Pol III binding sites are found near their promoters. However, these Pol III binding sites do not correspond to transfer RNAs. Moreover, we demonstrate that Pol III regulates Pol II transcription and chromatin binding of the facilitates chromatin transcription (FACT) complex to alter local chromatin structures, which in turn affects the Pol II transcription rate. Our results support a model suggesting that RNA polymerases show cross-regulatory effects: Pol III affects local chromatin structures and the FACT-Pol II axis to regulate the Pol II transcription rate at certain gene loci. This study provides a new perspective for understanding the dysregulation of Pol III in various tissues affected by developmental diseases.",{"EN":1165},"Cross-regulome profiling of RNA polymerases highlights the regulatory role of polymerase III on mRNA transcription by maintaining local chromatin architecture",{"VOID":1167},"Roeder RG, Rutter WJJN. Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature. 1969;224:234–7.\nCramer P. Eukaryotic transcription turns 50. Cell. 2019;179:808–12.\nLis JT. 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Gene Expression Omnibus. 2018. https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fgeo\u002Fquery\u002Facc.cgi?acc=GSE90906.",{"VOID":1169},"10.1186\u002Fs13059-022-02812-w","https:\u002F\u002Fgenomebiology.biomedcentral.com\u002Farticles\u002F10.1186\u002Fs13059-022-02812-w",[1172,1187,1200,1213,1246,1259,1286,1313],{"id":1173,"sortIndex":32,"researcher":28,"roles":1174,"affiliations":1175,"properties":1184},"e76ae4ce-28cf-44eb-abae-7fb5bf2ed5c2",[966],[1176],{"id":1177,"sortIndex":32,"affiliation":1178,"properties":28},"67b60a31-d991-428d-b88c-6f3063423621",{"id":1177,"createTime":28,"updateTime":28,"relativeEntities":1179,"slug":28,"properties":1180,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1183,"statistic":28},[],{"title":1181},{"VI":1182},"Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, 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in cell-cell interactions are a key feature of cancer. However, little is known about the systematic effects of cell-cell interaction on global gene expression in cancer. We used an ex vivo model to simulate tumor-stroma interaction by systematically co-cultivating breast cancer cells with stromal fibroblasts and determined associated gene expression changes with cDNA microarrays. In the complex picture of epithelial-mesenchymal interaction effects, a prominent characteristic was an induction of interferon-response genes (IRGs) in a subset of cancer cells. In close proximity to these cancer cells, the fibroblasts secreted type I interferons, which, in turn, induced expression of the IRGs in the tumor cells. Paralleling this model, immunohistochemical analysis of human breast cancer tissues showed that STAT1, the key transcriptional activator of the IRGs, and itself an IRG, was expressed in a subset of the cancers, with a striking pattern of elevated expression in the cancer cells in close proximity to the stroma. In vivo, expression of the IRGs was remarkably coherent, providing a basis for segregation of 295 early-stage breast cancers into two groups. Tumors with high compared to low expression levels of IRGs were associated with significantly shorter overall survival; 59% versus 80% at 10 years (log-rank p = 0.001). In an effort to deconvolute global gene expression profiles of breast cancer by systematic characterization of heterotypic interaction effects in vitro, we found that an interaction between some breast cancer cells and stromal fibroblasts can induce an interferon-response, and that this response may be associated with a greater propensity for tumor progression.",{"EN":1384},"Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer",{"VOID":1386},"Cunha GR, Hom YK: Role of mesenchymal-epithelial interactions in mammary gland development. 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Am J Pathol. 2002, 161: 1557-1565.",{"VOID":1388},"10.1186\u002Fgb-2007-8-9-r191","https:\u002F\u002Fgenomebiology.biomedcentral.com\u002Farticles\u002F10.1186\u002Fgb-2007-8-9-r191",[1391,1406,1421,1436,1451,1464],{"id":1392,"sortIndex":32,"researcher":28,"roles":1393,"affiliations":1394,"properties":1403},"a76c7b66-24aa-44f6-9f51-9eed9ab3a2a2",[966],[1395],{"id":1396,"sortIndex":32,"affiliation":1397,"properties":28},"13bf078e-ae2b-4d15-a9ed-8e93f238cb3e",{"id":1396,"createTime":28,"updateTime":28,"relativeEntities":1398,"slug":28,"properties":1399,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1402,"statistic":28},[],{"title":1400},{"VI":1401},"Department of Biochemistry, Stanford University School of Medicine, Stanford, USA",[],{"title":1404},{"VI":1405},"Martin 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Hastie",{"id":1437,"sortIndex":42,"researcher":28,"roles":1438,"affiliations":1439,"properties":1448},"ed7b8ea0-a86b-4841-b5c2-e9ff65131a4d",[966],[1440],{"id":1441,"sortIndex":32,"affiliation":1442,"properties":28},"61e0b005-6116-42de-a348-2cccff1be6cd",{"id":1441,"createTime":28,"updateTime":28,"relativeEntities":1443,"slug":28,"properties":1444,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1447,"statistic":28},[],{"title":1445},{"VI":1446},"Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada",[],{"title":1449},{"VI":1450},"Torsten 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USA",[],{},{"title":1484},{"VI":1485},"Patrick O Brown",{"url":1389,"publisher":1487,"properties":1526},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1488,"slug":872,"properties":1489,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1492,"manageAffiliations":1501,"indexDatabases":1507,"url":28,"thumbnailPath":28,"statistic":1521,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":1490,"title":1491},{"VOID":875},{"EN":877},[1493,1497],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":1494,"label":1495,"description":1496,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":1498,"label":1499,"description":1500,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[1502],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":1503,"slug":28,"properties":1504,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1506,"statistic":28},[],{"title":1505},{"EN":900},[],[1508,1514],{"id":904,"indexDatabase":1509,"url":910,"indexYears":911,"academicFieldIds":28,"indexDatabaseRanking":912},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":1510,"label":1511,"description":1512,"key":781,"publicationTags":1513,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],{"id":914,"indexDatabase":1515,"url":926,"indexYears":28,"academicFieldIds":1520,"indexDatabaseRanking":28},{"id":916,"createTime":28,"updateTime":28,"relativeEntities":1516,"label":1517,"description":1518,"key":923,"publicationTags":1519,"standard":28},[],{"EN":919,"VI":919},{"EN":921,"VI":922},[925,813],[928,929],{"impactFactor":32,"impactFactorByYear":1522,"i10Index":42,"i10IndexLast5Year":40,"totalPublication":933,"totalPublicationByYear":1523,"totalCitation":935,"totalCitationByYear":1524,"totalCitationPerPublication":698,"totalCitationPerPublicationByYear":1525,"hindexLast5Year":42,"hindex":42},{"2018":932,"2019":705,"2022":222,"2023":118},{"2000":49,"2001":49,"2002":47,"2003":45,"2004":48,"2005":45,"2006":45,"2007":48,"2008":46,"2009":46,"2010":48,"2011":42,"2012":45,"2014":40,"2016":123,"2017":49,"2018":42,"2019":46,"2020":46,"2021":205,"2022":45,"2023":48,"2024":134},{"2017":451,"2021":126},{"2017":938,"2021":939},{"pages":1527,"volume":1528},{"VOID":1074},{"VOID":1529},"8","2007-09-14",2007,[925,912],{"id":1534,"createTime":1535,"updateTime":1536,"relativeEntities":1537,"slug":1538,"properties":1539,"entityType":959,"verifyStatus":26,"verifyTime":1536,"verifyNote":960,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":1548,"fullTextUrl":28,"authors":1549,"publicationType":1031,"publisherRelationship":1806,"citationCount":28,"citationInfo":28,"publishDate":1851,"publishYear":1852,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":1853,"openAccess":28,"references":28,"isForceReanalyzing":1080},"002ecf6c-f0c0-4586-ab59-d45a4f1e0900","2024-01-12T19:47:25.327+00:00","2025-02-10T11:37:26.487+00:00",[],"Genomic-signatures-accompanying-the-dietary-shift-to-phytophagy-in-polyphagan-beetles",{"abstract":1540,"title":1542,"references":1544,"doi":1546},{"EN":1541},"The diversity and evolutionary success of beetles (Coleoptera) are proposed to be related to the diversity of plants on which they feed. Indeed, the largest beetle suborder, Polyphaga, mostly includes plant eaters among its approximately 315,000 species. In particular, plants defend themselves with a diversity of specialized toxic chemicals. These may impose selective pressures that drive genomic diversification and speciation in phytophagous beetles. However, evidence of changes in beetle gene repertoires driven by such interactions remains largely anecdotal and without explicit hypothesis testing. We explore the genomic consequences of beetle-plant trophic interactions by performing comparative gene family analyses across 18 species representative of the two most species-rich beetle suborders. We contrast the gene contents of species from the mostly plant-eating suborder Polyphaga with those of the mainly predatory Adephaga. We find gene repertoire evolution to be more dynamic, with significantly more adaptive lineage-specific expansions, in the more speciose Polyphaga. Testing the specific hypothesis of adaptation to plant feeding, we identify families of enzymes putatively involved in beetle-plant interactions that underwent adaptive expansions in Polyphaga. There is notable support for the selection hypothesis on large gene families for glutathione S-transferase and carboxylesterase detoxification enzymes. Our explicit modeling of the evolution of gene repertoires across 18 species identifies putative adaptive lineage-specific gene family expansions that accompany the dietary shift towards plants in beetles. These genomic signatures support the popular hypothesis of a key role for interactions with plant chemical defenses, and for plant feeding in general, in driving beetle diversification.",{"EN":1543},"Genomic signatures accompanying the dietary shift to phytophagy in polyphagan beetles",{"VOID":1545},"Farrell BD. “Inordinate Fondness” explained: why are there so many beetles? Science. 1998;281:555–9.\nGrimaldi DA, Engel MS. 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Waterhouse",{"id":1785,"sortIndex":126,"researcher":28,"roles":1786,"affiliations":1787,"properties":1803},"6bd20b78-c042-418c-b478-ad86e03266c4",[966],[1788,1794],{"id":1555,"sortIndex":32,"affiliation":1789,"properties":28},{"id":1555,"createTime":28,"updateTime":28,"relativeEntities":1790,"slug":28,"properties":1791,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1793,"statistic":28},[],{"title":1792},{"VI":1560},[],{"id":1795,"sortIndex":40,"affiliation":1796,"properties":1802},"20945387-ed7f-40b0-9598-b9afe9369365",{"id":1795,"createTime":28,"updateTime":28,"relativeEntities":1797,"slug":28,"properties":1798,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1801,"statistic":28},[],{"title":1799},{"VI":1800},"Geneva Natural History Museum, Geneva, Switzerland",[],{},{"title":1804},{"VI":1805},"Nadir Alvarez",{"url":1548,"publisher":1807,"properties":1846},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":1808,"slug":872,"properties":1809,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":1812,"manageAffiliations":1821,"indexDatabases":1827,"url":28,"thumbnailPath":28,"statistic":1841,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":1810,"title":1811},{"VOID":875},{"EN":877},[1813,1817],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":1814,"label":1815,"description":1816,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":1818,"label":1819,"description":1820,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[1822],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":1823,"slug":28,"properties":1824,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":1826,"statistic":28},[],{"title":1825},{"EN":900},[],[1828,1834],{"id":904,"indexDatabase":1829,"url":910,"indexYears":911,"academicFieldIds":28,"indexDatabaseRanking":912},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":1830,"label":1831,"description":1832,"key":781,"publicationTags":1833,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],{"id":914,"indexDatabase":1835,"url":926,"indexYears":28,"academicFieldIds":1840,"indexDatabaseRanking":28},{"id":916,"createTime":28,"updateTime":28,"relativeEntities":1836,"label":1837,"description":1838,"key":923,"publicationTags":1839,"standard":28},[],{"EN":919,"VI":919},{"EN":921,"VI":922},[925,813],[928,929],{"impactFactor":32,"impactFactorByYear":1842,"i10Index":42,"i10IndexLast5Year":40,"totalPublication":933,"totalPublicationByYear":1843,"totalCitation":935,"totalCitationByYear":1844,"totalCitationPerPublication":698,"totalCitationPerPublicationByYear":1845,"hindexLast5Year":42,"hindex":42},{"2018":932,"2019":705,"2022":222,"2023":118},{"2000":49,"2001":49,"2002":47,"2003":45,"2004":48,"2005":45,"2006":45,"2007":48,"2008":46,"2009":46,"2010":48,"2011":42,"2012":45,"2014":40,"2016":123,"2017":49,"2018":42,"2019":46,"2020":46,"2021":205,"2022":45,"2023":48,"2024":134},{"2017":451,"2021":126},{"2017":938,"2021":939},{"pages":1847,"volume":1849},{"VOID":1848},"1-14",{"VOID":1850},"20","2019-05-17",2019,[925,912],{"id":1855,"createTime":1856,"updateTime":1857,"relativeEntities":1858,"slug":1859,"properties":1860,"entityType":959,"verifyStatus":880,"verifyTime":1857,"verifyNote":1869,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":1870,"fullTextUrl":28,"authors":1871,"publicationType":1031,"publisherRelationship":2675,"citationCount":28,"citationInfo":28,"publishDate":2719,"publishYear":1852,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":2720,"openAccess":28,"references":28,"isForceReanalyzing":1080},"003ee121-d971-410a-aaa7-3acce9e67c25","2024-01-15T11:21:19.143+00:00","2025-02-09T07:01:30.430+00:00",[],"Comparative-genomic-analysis-of-six-Glossina-genomes-vectors-of-African-trypanosomes",{"abstract":1861,"title":1863,"references":1865,"doi":1867},{"EN":1862},"Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate viviparity), a vertebrate blood-specific diet by both sexes, and obligate bacterial symbiosis. This work describes the comparative analysis of six Glossina genomes representing three sub-genera: Morsitans (G. morsitans morsitans, G. pallidipes, G. austeni), Palpalis (G. palpalis, G. fuscipes), and Fusca (G. brevipalpis) which represent different habitats, host preferences, and vectorial capacity. Genomic analyses validate established evolutionary relationships and sub-genera. Syntenic analysis of Glossina relative to Drosophila melanogaster shows reduced structural conservation across the sex-linked X chromosome. Sex-linked scaffolds show increased rates of female-specific gene expression and lower evolutionary rates relative to autosome associated genes. Tsetse-specific genes are enriched in protease, odorant-binding, and helicase activities. Lactation-associated genes are conserved across all Glossina species while male seminal proteins are rapidly evolving. Olfactory and gustatory genes are reduced across the genus relative to other insects. Vision-associated Rhodopsin genes show conservation of motion detection\u002Ftracking functions and variance in the Rhodopsin detecting colors in the blue wavelength ranges. Expanded genomic discoveries reveal the genetics underlying Glossina biology and provide a rich body of knowledge for basic science and disease control. They also provide insight into the evolutionary biology underlying novel adaptations and are relevant to applied aspects of vector control such as trap design and discovery of novel pest and disease control strategies.",{"EN":1864},"Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes",{"VOID":1866},"Lyons M. The colonial disease. A social history of sleeping sickness in norther Zaire, 1900–1940. 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in the postgenomic era: simple or complex?",{"VOID":2731},"10.1186\u002Fgb-2000-1-4-reports4018",{"EN":2733},"A report on the Third Genetic Effects on Aging Meeting, The Jackson Laboratory, Bar Harbor, Maine, August 4-8, 2000.","https:\u002F\u002Fgenomebiology.biomedcentral.com\u002Farticles\u002F10.1186\u002Fgb-2000-1-4-reports4018",[2736],{"id":2737,"sortIndex":32,"researcher":28,"roles":2738,"affiliations":2739,"properties":2748},"f781188c-7f39-4db2-ac71-861c3ea347db",[966],[2740],{"id":2741,"sortIndex":32,"affiliation":2742,"properties":28},"473d9b57-8cff-4208-9c9f-c5d97df02d27",{"id":2741,"createTime":28,"updateTime":28,"relativeEntities":2743,"slug":28,"properties":2744,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2747,"statistic":28},[],{"title":2745},{"VI":2746},"Department of Genetics, North Carolina State University, Raleigh, USA",[],{"title":2749},{"VI":2750},"Trudy FC Mackay",{"url":2734,"publisher":2752,"properties":2791},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":2753,"slug":872,"properties":2754,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":2757,"manageAffiliations":2766,"indexDatabases":2772,"url":28,"thumbnailPath":28,"statistic":2786,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":2755,"title":2756},{"VOID":875},{"EN":877},[2758,2762],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":2759,"label":2760,"description":2761,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":2763,"label":2764,"description":2765,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[2767],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":2768,"slug":28,"properties":2769,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2771,"statistic":28},[],{"title":2770},{"EN":900},[],[2773,2779],{"id":904,"indexDatabase":2774,"url":910,"indexYears":911,"academicFieldIds":28,"indexDatabaseRanking":912},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":2775,"label":2776,"description":2777,"key":781,"publicationTags":2778,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],{"id":914,"indexDatabase":2780,"url":926,"indexYears":28,"academicFieldIds":2785,"indexDatabaseRanking":28},{"id":916,"createTime":28,"updateTime":28,"relativeEntities":2781,"label":2782,"description":2783,"key":923,"publicationTags":2784,"standard":28},[],{"EN":919,"VI":919},{"EN":921,"VI":922},[925,813],[928,929],{"impactFactor":32,"impactFactorByYear":2787,"i10Index":42,"i10IndexLast5Year":40,"totalPublication":933,"totalPublicationByYear":2788,"totalCitation":935,"totalCitationByYear":2789,"totalCitationPerPublication":698,"totalCitationPerPublicationByYear":2790,"hindexLast5Year":42,"hindex":42},{"2018":932,"2019":705,"2022":222,"2023":118},{"2000":49,"2001":49,"2002":47,"2003":45,"2004":48,"2005":45,"2006":45,"2007":48,"2008":46,"2009":46,"2010":48,"2011":42,"2012":45,"2014":40,"2016":123,"2017":49,"2018":42,"2019":46,"2020":46,"2021":205,"2022":45,"2023":48,"2024":134},{"2017":451,"2021":126},{"2017":938,"2021":939},{"pages":2792,"volume":2794},{"VOID":2793},"1-6",{"VOID":2795},"1","2000-10-16",2000,[925,912],{"id":2800,"createTime":2801,"updateTime":2802,"relativeEntities":2803,"slug":2804,"properties":2805,"entityType":959,"verifyStatus":880,"verifyTime":2802,"verifyNote":1869,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":2812,"fullTextUrl":28,"authors":2813,"publicationType":1031,"publisherRelationship":2821,"citationCount":28,"citationInfo":28,"publishDate":2865,"publishYear":2866,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":2867,"openAccess":28,"references":28,"isForceReanalyzing":1080},"00523e0c-1d06-4153-9927-9b1bede1dbd1","2023-11-29T08:24:35.714+00:00","2025-01-11T00:02:42.561+00:00",[],"Alternate-cell-death-program-identified",{"title":2806,"references":2808,"doi":2810},{"EN":2807},"Alternate cell-death program identified",{"VOID":2809},"A.G. Yakolev, A.I. Faden, \"Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies,\" Neurorx, 1:5-16, January 2004.\nA. Degterev et al., \"Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury,\" Nat Cell Biol, DOI:10.1038\u002Fnchembio711, May 29, 2005., [http:\u002F\u002Fwww.nature.com\u002Fnchembio\u002F]\nJunying Yuan, [http:\u002F\u002Fcellbio.med.harvard.edu\u002Ffaculty\u002Fyuan\u002F]\nShai Shaham, [http:\u002F\u002Fwww.rockefeller.edu\u002Flabheads\u002Fshaham\u002Fshaham-lab.php]\nH. Matsumura et al., \"Necrotic death pathway in Fas receptor signaling,\" J Chem Biol, 151:1247-56, December 11, 2000.\nAlan I. Faden, [http:\u002F\u002Fwww.neuro.georgetown.edu\u002Ffaden.htm]\nE.H. Lo et al., \"Mechanisms, challenges and opportunities in stroke,\" Nat Rev Neurosci. 4:399-415, May 2003.",{"VOID":2811},"10.1186\u002Fgb-spotlight-20050603-01","http:\u002F\u002Fgenomebiology.biomedcentral.com\u002Farticles\u002F10.1186\u002Fgb-spotlight-20050603-01",[2814],{"id":2815,"sortIndex":32,"researcher":28,"roles":2816,"affiliations":2817,"properties":2818},"05f34d18-870e-414b-b048-68cd1a9884cd",[966],[],{"title":2819},{"VI":2820},"Melissa Lee Phillips",{"url":2812,"publisher":2822,"properties":2861},{"id":868,"createTime":869,"updateTime":870,"relativeEntities":2823,"slug":872,"properties":2824,"entityType":25,"verifyStatus":880,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":32,"subjectFields":2827,"manageAffiliations":2836,"indexDatabases":2842,"url":28,"thumbnailPath":28,"statistic":2856,"gsStatistic":28,"type":55,"analyzePriority":28},[],{"issn":2825,"title":2826},{"VOID":875},{"EN":877},[2828,2832],{"id":883,"createTime":28,"updateTime":28,"relativeEntities":2829,"label":2830,"description":2831,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":886},{},{"id":889,"createTime":28,"updateTime":28,"relativeEntities":2833,"label":2834,"description":2835,"parentId":28,"standard":28,"scholarHubFieldId":28},[],{"EN":892},{},[2837],{"id":896,"createTime":28,"updateTime":28,"relativeEntities":2838,"slug":28,"properties":2839,"entityType":28,"verifyStatus":28,"verifyTime":28,"verifyNote":28,"languages":28,"translateLanguages":28,"viewCount":28,"url":28,"parentIds":2841,"statistic":28},[],{"title":2840},{"EN":900},[],[2843,2849],{"id":904,"indexDatabase":2844,"url":910,"indexYears":911,"academicFieldIds":28,"indexDatabaseRanking":912},{"id":775,"createTime":28,"updateTime":28,"relativeEntities":2845,"label":2846,"description":2847,"key":781,"publicationTags":2848,"standard":28},[],{"EN":778,"VI":778},{"EN":778,"VI":780},[783],{"id":914,"indexDatabase":2850,"url":926,"indexYears":28,"academicFieldIds":2855,"indexDatabaseRanking":28},{"id":916,"createTime":28,"updateTime":28,"relativeEntities":2851,"label":2852,"description":2853,"key":923,"publicationTags":2854,"standard":28},[],{"EN":919,"VI":919},{"EN":921,"VI":922},[925,813],[928,929],{"impactFactor":32,"impactFactorByYear":2857,"i10Index":42,"i10IndexLast5Year":40,"totalPublication":933,"totalPublicationByYear":2858,"totalCitation":935,"totalCitationByYear":2859,"totalCitationPerPublication":698,"totalCitationPerPublicationByYear":2860,"hindexLast5Year":42,"hindex":42},{"2018":932,"2019":705,"2022":222,"2023":118},{"2000":49,"2001":49,"2002":47,"2003":45,"2004":48,"2005":45,"2006":45,"2007":48,"2008":46,"2009":46,"2010":48,"2011":42,"2012":45,"2014":40,"2016":123,"2017":49,"2018":42,"2019":46,"2020":46,"2021":205,"2022":45,"2023":48,"2024":134},{"2017":451,"2021":126},{"2017":938,"2021":939},{"pages":2862,"volume":2863},{"VOID":1149},{"VOID":2864},"6","2005-06-03",2005,[925,912],{"id":2869,"createTime":2870,"updateTime":2871,"relativeEntities":2872,"slug":2873,"properties":2874,"entityType":959,"verifyStatus":880,"verifyTime":2871,"verifyNote":1869,"languages":28,"translateLanguages":28,"viewCount":32,"primaryUrl":2883,"fullTextUrl":28,"authors":2884,"publicationType":1031,"publisherRelationship":3058,"citationCount":28,"citationInfo":28,"publishDate":3102,"publishYear":1372,"citationAnalyzeStatus":880,"lastCitationAnalyze":28,"indexDatabases":3103,"openAccess":28,"references":28,"isForceReanalyzing":1080},"0060de1c-4153-48e1-9bd4-1058ffa6d124","2023-12-28T07:20:03.201+00:00","2025-01-15T11:40:51.933+00:00",[],"Functional-genomics-analysis-identifies-T-and-NK-cell-activation-as-a-driver-of-epigenetic-clock-progression",{"abstract":2875,"title":2877,"references":2879,"doi":2881},{"EN":2876},"Epigenetic clocks use DNA methylation (DNAm) levels of specific sets of CpG dinucleotides to accurately predict individual chronological age. A popular application of these clocks is to explore whether the deviation of predicted age from chronological age is associated with disease phenotypes, where this deviation is interpreted as a potential biomarker of biological age. This wide application, however, contrasts with the limited insight in the processes that may drive the running of epigenetic clocks. We perform a functional genomics analysis on four epigenetic clocks, including Hannum’s blood predictor and Horvath’s multi-tissue predictor, using blood DNA methylome and transcriptome data from 3132 individuals. The four clocks result in similar predictions of individual chronological age, and their constituting CpGs are correlated in DNAm level and are enriched for similar histone modifications and chromatin states. Interestingly, DNAm levels of CpGs from the clocks are commonly associated with gene expression in trans. The gene sets involved are highly overlapping and enriched for T cell processes. Further analysis of the transcriptome and methylome of sorted blood cell types identifies differences in DNAm between naive and activated T and NK cells as a probable contributor to the clocks. Indeed, within the same donor, the four epigenetic clocks predict naive cells to be up to 40 years younger than activated cells. The ability of epigenetic clocks to predict chronological age involves their ability to detect changes in proportions of naive and activated immune blood cells, an established feature of immuno-senescence. This finding may contribute to the interpretation of associations between clock-derived measures and age-related health outcomes.",{"EN":2878},"Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression",{"VOID":2880},"Bocklandt S, Lin W, Sehl ME, Sanchez FJ, Sinsheimer JS, Horvath S, et al. Epigenetic predictor of age. PLoS One. 2011\u002F07\u002F07 ed. 2011;6:e14821.\nHannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2012\u002F11\u002F28 ed. 2013;49:359–67.\nHorvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013\u002F10\u002F22 ed. 2013;14:R115.\nHorvath S, Oshima J, Martin GM, Lu AT, Quach A, Cohen H, et al. Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies. Aging (Albany NY). 2018\u002F07\u002F27 ed. 2018;10:1758–75.\nZhang Q, Vallerga CL, Walker RM, Lin T, Henders AK, Montgomery GW, et al. Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Med. 2019\u002F08\u002F25 ed, 54. 2019;11.\nBell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, et al. DNA methylation aging clocks: challenges and recommendations. 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Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics. BMJ Open. 2015\u002F09\u002F01 ed. 2015;5:e006772.\nWestendorp RG, van Heemst D, Rozing MP, Frolich M, Mooijaart SP, Blauw GJ, et al. Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study. J Am Geriatr Soc. 2009\u002F08\u002F18 ed. 2009;57:1634–7.\nBoomsma DI, Vink JM, van Beijsterveldt TC, de Geus EJ, Beem AL, Mulder EJ, et al. Netherlands Twin Register: a focus on longitudinal research. Twin Res. 2003\u002F01\u002F23 ed. 2002;5:401–6.\nHofman A, Brusselle GG, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, et al. The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol. 2015\u002F09\u002F21 ed. 2015;30:661–708.\nHuisman MH, de Jong SW, van Doormaal PT, Weinreich SS, Schelhaas HJ, van der Kooi AJ, et al. Population based epidemiology of amyotrophic lateral sclerosis using capture-recapture methodology. J Neurol Neurosurg Psychiatry. 2011\u002F05\u002F31 ed. 2011;82:1165–70.\nvan Iterson M, Cats D, Hop P, Consortium B, Heijmans BT. omicsPrint: detection of data linkage errors in multiple omics studies. Bioinformatics. 2018\u002F02\u002F09 ed. 2018;34:2142–3.\nDekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, et al. Blood lipids influence DNA methylation in circulating cells. Genome Biol. 2016\u002F06\u002F29 ed. 2016;17:138.\nSlieker RC, van Iterson M, Luijk R, Beekman M, Zhernakova DV, Moed MH, et al. Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. Genome Biol. 2016\u002F09\u002F23 ed. 2016;17:191.\nHop PJ, Luijk R, Daxinger L, van Iterson M, Dekkers KF, Jansen R, et al. Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference. 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J Comput Biol. 2011, 18: 1693-1707. 10.1089\u002Fcmb.2011.0171.\nLi W, Jiang T: Transcriptome assembly and isoform expression level estimation from biased RNA-Seq reads. Bioinformatics. 2012, 28: 2914-2921. 10.1093\u002Fbioinformatics\u002Fbts559.\nMezlini AM, Smith EJM, Fiume M, Buske O, Savich GL, Shah S, Aparicio S, Chiang DY, Goldenberg A, Brudno M: iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data. Genome Res. 2013, 23: 519-529. 10.1101\u002Fgr.142232.112.\nTomescu AI, Kuosmanen A, Rizzi R, Mäkinen V: A novel min-cost flow method for estimating transcript expression with RNA-Seq. BMC Bioinformatics. 2013, 14: S15-\nBernard E, Jacob L, Mairal J, Vert J-P: Efficient RNA isoform identification and quantification from RNA-Seq data with network flows. 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